Ouchi Hitoshi 大内仁志

Researcher Number	70798842
Other IDs
Affiliation (based on the past Project Information) *help	2020 – 2025: 静岡県立大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related Except Principal Investigator Science and Engineering
Keywords	Principal Investigator カイニン酸受容体 / ドウモイ酸 / カイノイド / 全合成 Except Principal Investigator フェアリーリング / 植物ホルモン / フェアリー化合物

ビスピペリジン骨格を有する天然有機化合物の合成法開発Principal Investigator
- Principal Investigator
  
  大内仁志
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  University of Shizuoka
Synthetic study of new kainate receptors selective molecules based on the total synthesis of domoic acidPrincipal Investigator
- Principal Investigator
  
  Ouchi Hitoshi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  University of Shizuoka
Science of fairy chemicals and their application development
- Principal Investigator
  
  河岸洋和
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
- Research Institution
  Shizuoka University

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] The role of xanthine dioxygenase in the biosynthetic pathway of 2-aza-8-oxohypoxanthine of Lepista sordida2023
- Author(s)
  Kotajima, M., Choi, J.-H., Suzuki, T., Wu, J., Hirai, H., Nelson, D. C., Ouchi, H., Inai, M., Dohra, H., Kawagishi, H.
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 87 Issue: 4 Pages: 420-425
- DOI
  10.1093/bbb/zbad005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22330, KAKENHI-PROJECT-22K06531, KAKENHI-PROJECT-20H05620
[Journal Article] Identification of Biosynthetic and Metabolic Genes of 2-Azahypoxanthine in Lepista sordida Based on Transcriptomic Analysis2023
- Author(s)
  37)Kotajima, M., Choi, J.-H., Suzuki, H., Suzuki, T., Wu, J., Hirai, H., Nelson, D. C., Ouchi, H., Inai, M., Dohra, H., Kawagishi, H.
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 86 Issue: 4 Pages: 710-718
- DOI
  10.1021/acs.jnatprod.2c00789
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19174, KAKENHI-PROJECT-19K22330, KAKENHI-PROJECT-22K06531, KAKENHI-PROJECT-20H05620
[Journal Article] Role of hypoxanthine-guanine phosphoribosyltransferase in the salvage pathway of fairy chemicals in rice2023
- Author(s)
  38)Takemura, H., Choi, J-H., Fushimi, K., Narikawa, R., Kondo, M., Wu, J., Nelson, D. C., Suzuki, T., Ouchi, H., Inai, M., Hirai, H., and Kawagishi, H.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 21 Issue: 12 Pages: 2556-2561
- DOI
  10.1039/d3ob00026e
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19174, KAKENHI-PROJECT-19K22330, KAKENHI-PROJECT-22K06531, KAKENHI-PROJECT-20H05620
[Journal Article] 1,2,3-Triazine formation mechanism of the fairy chemical 2-azahypoxanthine in the fairy ring-forming fungus Lepista sordida2022
- Author(s)
  Ito Akinobu、Choi Jae-Hoon、Yokoyama-Maruyama Waki、Kotajima Mihaya、Wu Jing、Suzuki Tomohiro、Terashima Yurika、Suzuki Hyogo、Hirai Hirofumi、Nelson David C.、Tsunematsu Yuta、Watanabe Kenji、Asakawa Tomohiro、Ouchi Hitoshi、Inai Makoto、Dohra Hideo、Kawagishi Hirokazu
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 20 Issue: 13 Pages: 2636-2642
- DOI
  10.1039/d2ob00328g
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05866, KAKENHI-PROJECT-19K22330, KAKENHI-PROJECT-22K06531, KAKENHI-PROJECT-20H05620
[Journal Article] S-Adenosylhomocysteine Analogue of a Fairy Chemical, Imidazole-4-carboxamide, as its Metabolite in Rice and Yeast and Synthetic Investigations of Related Compounds2021
- Author(s)
  Hitoshi Ouchi , Takuya Namiki , Kenji Iwamoto , Nobuo Matsuzaki , Makoto Inai , Mihaya Kotajima , Jing Wu , Jae-Hoon Choi , Yoko Kimura , Hirofumi Hirai , Xiaonan Xie , Hirokazu Kawagishi , Toshiyuki Kan
- Journal Title
  
  J Nat Prod .
  
  Volume: 84 Issue: 2 Pages: 453-458
- DOI
  10.1021/acs.jnatprod.0c01269
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06620, KAKENHI-PROJECT-18K05452, KAKENHI-PROJECT-19K05460, KAKENHI-PROJECT-20K15958, KAKENHI-PROJECT-20H05620
[Journal Article] Total Synthesis of Sophoraflavanone H and Confirmation of Its Absolute Configuration2020
- Author(s)
  Murakami Haruka、Asakawa Tomohiro、Muramatsu Yoshihiro、Ishikawa Ryo、Hiza Aiki、Tsukaguchi Yuta、Tokumaru Yohei、Egi Masahiro、Inai Makoto、Ouchi Hitoshi、Yoshimura Fumihiko、Taniguchi Tohru、Ishikawa Yoshinobu、Kondo Mitsuru、Kan Toshiyuki
- Journal Title
  
  Organic Letters
  
  Volume: 22 Issue: 10 Pages: 3820-3824
- DOI
  10.1021/acs.orglett.0c01063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05460, KAKENHI-PROJECT-20K06946, KAKENHI-PROJECT-20K15958, KAKENHI-PROJECT-18K07315
[Journal Article] Biosynthesis of the Fairy Chemicals, 2-Azahypoxanthine and Imidazole-4-carboxamide, in the Fairy Ring-Forming FungusLepista sordida2020
- Author(s)
  Ito Akinobu、Choi Jae-Hoon、Takemura Hirohide、Kotajima Mihaya、Wu Jing、Tokuyama Shinji、Hirai Hirofumi、Asakawa Tomohiro、Ouchi Hitoshi、Inai Makoto、Kan Toshiyuki、Kawagishi Hirokazu
- Journal Title
  
  Journal of Natural Products
  
  Volume: 83 Issue: 8 Pages: 2469-2476
- DOI
  10.1021/acs.jnatprod.0c00394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05460, KAKENHI-PROJECT-20K15958, KAKENHI-PLANNED-17H06402, KAKENHI-PROJECT-18J21506, KAKENHI-PROJECT-20J14421, KAKENHI-PROJECT-20H05620
[Journal Article] Synthetic Studies on Pactamycin: A Synthesis of Johnson’s Intermediate2020
- Author(s)
  Miura Yusuke、Ouchi Hitoshi、Inai Makoto、Osawa Taisei、Yoshimura Fumihiko、Kanazawa Junichiro、Uchiyama Masanobu、Kondo Mitsuru、Kan Toshiyuki
- Journal Title
  
  Organic Letters
  
  Volume: 22 Issue: 9 Pages: 3515-3518
- DOI
  10.1021/acs.orglett.0c00959
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K23621, KAKENHI-PROJECT-19K05460, KAKENHI-PROJECT-20K15958, KAKENHI-PROJECT-17H06173
[Journal Article] Pactamycin and Its Derivatives: Improved Synthesis Route2020
- Author(s)
  Kohki Ohmi, Yusuke Miura, Yuta Nakao, Atsumi Goto, Satoshi Yoshimura, Hitoshi Ouchi, Makoto Inai, Tomohiro Asakawa, Fumihiko Yoshimura, Mitsuru Kondo, Toshiyuki Kan
- Journal Title
  
  European Journal of Organic Chemistry
  
  Volume: 2020 Issue: 4 Pages: 488-491
- DOI
  10.1002/ejoc.201901747
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04424, KAKENHI-PROJECT-17H03973, KAKENHI-PROJECT-19K05460, KAKENHI-PROJECT-20K15958
[Presentation] フェアリー化合物由来SAMとSAHアナログとメチル化機構の関係2024
- Author(s)
  久米こころ、崔宰熏、道羅英夫、謝肖男、大内仁志、稲井誠、滝田良、平井浩文、河岸洋和
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-20H05620
[Presentation] フェアリー化合物由来SAMとSAHアナログとメチル化機構の関係2023
- Author(s)
  久米こころ, 崔宰熏, 道羅英夫, 謝肖男, 大内仁志, 滝田良, 平井浩文, 河岸洋和
- Organizer
  植物化学調節学会第58回大会
- Data Source
  KAKENHI-PROJECT-20H05620
[Presentation] コムラサキシメジにおける2-azahypoxanthineに特異なトリアジン基の形成機構に関する研究2021
- Author(s)
  鈴木兵梧，伊藤彰将，古田島美颯，崔宰熏，鈴木智大，平井浩文，浅川倫宏，大内仁志，稲井誠，菅敏幸，道羅英夫，河岸洋和
- Organizer
  農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-20H05620
[Presentation] ICAの代謝産物であるS-ICAr-Hの存在意義についての研究2021
- Author(s)
  古田島美颯，崔宰熏，呉静，謝肖男，木村洋子，道羅英夫，大西利幸，平井浩文，浅川倫宏，大内仁志，稲井誠，菅敏幸，河岸洋和
- Organizer
  農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-20H05620
[Presentation] ケミカルバイオロジーを志向した天然物の全合成2021
- Author(s)
  大内仁志
- Organizer
  令和3年度有機合成化学協会東海支部若手研究者のためのセミナー
- Data Source
  KAKENHI-PROJECT-20K15958
[Presentation] フェアリー化合物の合成研究2021
- Author(s)
  岩本拳司，並木拓哉，大内仁志，稲井誠，吉村文彦，崔宰熏，河岸洋和，菅敏幸
- Organizer
  農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-20H05620
[Presentation] フェアリー化合物の合成研究2020
- Author(s)
  岩本拳司，並木拓哉，大内仁志，稲井誠，吉村文彦，崔宰熏，河岸洋和，菅敏幸
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会
- Data Source
  KAKENHI-PROJECT-20H05620
[Presentation] フェアリー化合物の生合成経路の解明と代謝産物の存在意義2020
- Author(s)
  古田島美颯，伊藤彰将，崔宰熏，呉静，道羅英夫，謝肖男，鈴木智大，徳山真治，平井浩文，浅川倫宏，大内仁志，稲井誠，菅敏幸，河岸洋和
- Organizer
  第62回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-20H05620

1. 河岸洋和 (70183283)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. 天池一真 (00866600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 鈴木智大 (10649601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 室井誠 (30261168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 高橋公咲 (30374622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 謝肖男 (30610323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 野村崇人 (60373346)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 一家崇志 (90580647)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 菅敏幸 (10221904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
10. 伊藤英人 (70706704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. DOHRA Hideo

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 木村洋子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 恒松雄太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 崔宰熏

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
15. 稲井誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 金澤純一朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ouchi Hitoshi 大内 仁志

Research Projects

Research Products

Co-Researchers

ビスピペリジン骨格を有する天然有機化合物の合成法開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Synthetic study of new kainate receptors selective molecules based on the total synthesis of domoic acidPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Science of fairy chemicals and their application development

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] The role of xanthine dioxygenase in the biosynthetic pathway of 2-aza-8-oxohypoxanthine of Lepista sordida2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of Biosynthetic and Metabolic Genes of 2-Azahypoxanthine in Lepista sordida Based on Transcriptomic Analysis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of hypoxanthine-guanine phosphoribosyltransferase in the salvage pathway of fairy chemicals in rice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 1,2,3-Triazine formation mechanism of the fairy chemical 2-azahypoxanthine in the fairy ring-forming fungus Lepista sordida2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] S-Adenosylhomocysteine Analogue of a Fairy Chemical, Imidazole-4-carboxamide, as its Metabolite in Rice and Yeast and Synthetic Investigations of Related Compounds2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Total Synthesis of Sophoraflavanone H and Confirmation of Its Absolute Configuration2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Biosynthesis of the Fairy Chemicals, 2-Azahypoxanthine and Imidazole-4-carboxamide, in the Fairy Ring-Forming FungusLepista sordida2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthetic Studies on Pactamycin: A Synthesis of Johnson’s Intermediate2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pactamycin and Its Derivatives: Improved Synthesis Route2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] フェアリー化合物由来SAMとSAHアナログとメチル化機構の関係2024

Author(s)

Organizer

Data Source

[Presentation] フェアリー化合物由来SAMとSAHアナログとメチル化機構の関係2023

Author(s)

Organizer

Data Source

[Presentation] コムラサキシメジにおける2-azahypoxanthineに特異なトリアジン基の形成機構に関する研究2021

Author(s)

Organizer

Data Source

[Presentation] ICAの代謝産物であるS-ICAr-Hの存在意義についての研究2021

Ouchi Hitoshi 大内仁志