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Shichino Shigeyuki  七野 成之

ORCIDConnect your ORCID iD *help
Researcher Number 70822435
Other IDs
Affiliation (Current) 2022: 東京理科大学, 研究推進機構生命医科学研究所, 助教
Affiliation (based on the past Project Information) *help 2022: 東京理科大学, 付置研究所, 助教
2018 – 2022: 東京理科大学, 研究推進機構生命医科学研究所, 助教
Review Section/Research Field
Principal Investigator
Basic Section 49030:Experimental pathology-related / Transformative Research Areas, Section (III)
Except Principal Investigator
Complex systems / Immunology / Basic Section 49030:Experimental pathology-related / Basic Section 53030:Respiratory medicine-related
Keywords
Principal Investigator
T細胞応答 / TCRレパトワ解析 / single-cell TCR-seq / single-cell RNA-seq / シングルセルTCR-seq / がん免疫 / 1細胞トランスクリプトーム / T細胞 / T細胞受容体 / バイオインフォマティクス … More
Except Principal Investigator
… More 肺線維症 / 免疫学 / 遺伝子 / 病理学 / モデル化 / 情報工学 / single-cell RNA-seq / 細胞間相互作用 / シングルセルトランスクリプトーム / 転写因子 / 線維芽細胞 / トランスクリプトーム / 線維症 / 脂質代謝 / TCRレパトア / 単一細胞解析 / 腫瘍免疫 / がん免疫 / T細胞 / T細胞受容体 / 1細胞解析 / じん肺 / 肺線維化 / シングルセル解析 / 肺がん / 病理 Less
  • Research Projects

    (6 results)
  • Research Products

    (59 results)
  • Co-Researchers

    (33 People)
  •  間葉系細胞-間質性細胞相互作用の肺-骨髄間クロストークの意義の解明Principal Investigator

    • Principal Investigator
      七野 成之
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Tokyo University of Science
  •  増殖の臓器指向性と一細胞遺伝子発現解析に基づく治療最適抗腫瘍T細胞クローンの同定

    • Principal Investigator
      上羽 悟史
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Tokyo University of Science
  •  新規シングルセル解析法を用いたじん肺発症-進展における包括的基盤研究

    • Principal Investigator
      山野 荘太郎
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Japan Organization of Occupational Health and Safety Japan Bioassay Research Center
  •  Investigation of the immune response of the tumor-infilteating T cells by novel scTCR-seq methodsPrincipal Investigator

    • Principal Investigator
      Shichino Shigeyuki
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Tokyo University of Science
  •  Inflammation cellular society in pulmonary fibrosis

    • Principal Investigator
      Matsushima Kouji
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Tokyo University of Science
      The University of Tokyo
  •  Mechanisms of transcriptional regulation of fibroblast activation in pulmonary fibrosis

    • Principal Investigator
      Matsushima Kouji
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Tokyo University of Science
      The University of Tokyo

All 2021 2020 2019 2018 2017 2016

All Journal Article Presentation Patent

  • [Journal Article] Transient Depletion of CD4+ Cells Induces Remodeling of the TCR Repertoire in Gastrointestinal Cancer.2021

    • Author(s)
      Aoki H, Ueha S, Shichino S, Ogiwara H, Shitara K, Shimomura M, Suzuki T, Nakatsura T, Yamashita M, Kitano S, Kuroda S, Wakabayashi M, Kurachi M, Ito S, Doi T, Matsushima K.
    • Journal Title

      Cancer Immunol Res

      Volume: 0 Pages: 0-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16620
  • [Journal Article] Transient Depletion of CD4 + Cells Induces Remodeling of the TCR Repertoire in Gastrointestinal Cancer2021

    • Author(s)
      Aoki H, Ueha S, Shichino S, Ogiwara H, Shitara K, Shimomura M, Suzuki T, Nakatsura T, Yamashita M, Kitano S, Kuroda S, Wakabayashi M, Kurachi M, Ito S, Doi T, Matsushima K.
    • Journal Title

      Cancer Immunol Res.

      Volume: -

    • DOI

      10.1158/2326-6066.cir-20-0989

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-17K07207
  • [Journal Article] Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer2021

    • Author(s)
      Nishina T, Deguchi Y, Ohshima D, Takeda W, Ohtsuka M, Shichino S, Ueha S, Yamazaki S, Kawauchi M, Nakamura E, Nishiyama C, Kojima Y, Adachi-Akahane S, Hasegawa M, Nakayama M, Oshima M, Yagita H, Shibuya K, Mikami T, Inohara N, Matsushima K, Tada N, Nakano H.
    • Journal Title

      Nat Commun

      Volume: 12 Pages: 0-0

    • DOI

      10.1038/s41467-021-22450-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06859, KAKENHI-PROJECT-20H02939, KAKENHI-PROJECT-20H03475, KAKENHI-PROJECT-19K16620
  • [Journal Article] The Increased Frequency of Methicillin-Resistant Staphylococcus Aureus With Low MIC of Beta-Lactam Antibiotics Isolated From Hospitalized Patients2020

    • Author(s)
      Iwata Y、Sakai N、Yoneda I、Satou K、Furuichi K、Senda Y、Sakai-Takemori Y、Wada T、Fujita S、Ogura H、Sato K、Minami T、Yamaguchi K、Kitajima S、Toyama T、Yamamura Y、Miyagawa T、Hara A、Shimizu M、Sakai Y、Ikeo K、Shichino S、Ueha S、Nakajima T、Matsushima K、Wada T
    • Journal Title

      J Infect Chemother

      Volume: 26 Pages: 604-610

    • DOI

      10.1016/j.jiac.2020.01.016

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06392, KAKENHI-PLANNED-17H06399, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06394
  • [Journal Article] Transcriptome network analysis identifies protective role of the LXR/SREBP-1c axis in murine pulmonary fibrosis2019

    • Author(s)
      Shichino S, Ueha S, Hashimoto S, Otsuji M, Abe J, Tsukui T, Deshimaru S, Nakajima T, Kosugi-Kanaya M, Shand FH, Inagaki Y, Shimano H, Matsushima K.
    • Journal Title

      JCI Insight

      Volume: 4(1) Pages: 122163-122163

    • DOI

      10.1172/jci.insight.122163

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-17H04166, KAKENHI-PROJECT-16K08730, KAKENHI-PROJECT-17K19546, KAKENHI-ORGANIZER-17H06391
  • [Journal Article] Mesenchymal-Epithelial Interactome Analysis Reveals Essential Factors Required for Fibroblast-Free Alveolosphere Formation.2019

    • Author(s)
      Shiraishi Kazushige、Shichino Shigeyuki、Ueha Satoshi、Nakajima Takuya、Hashimoto Shinichi、Yamazaki Satoshi、Matsushima Kouji
    • Journal Title

      iScience.

      Volume: 11 Pages: 318-333

    • DOI

      10.1016/j.isci.2018.12.022

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05095, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-17H05086, KAKENHI-PROJECT-16K08730
  • [Journal Article] In vitro expansion of endogenous human alveolar epithelial type II cells in fibroblast-free spheroid culture2019

    • Author(s)
      Shiraishi Kazushige、Nakajima Takuya、Shichino Shigeyuki、Deshimaru Shungo、Matsushima Kouji、Ueha Satoshi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 515 Pages: 579-585

    • DOI

      10.1016/j.bbrc.2019.05.187

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Journal Article] Engraftment and proliferation potential of embryonic lung tissue cells in irradiated mice with emphysema.2019

    • Author(s)
      Shiraishi Kazushige、Shichino Shigeyuki、Tsukui Tatsuya、Hashimoto Shinichi、Ueha Satoshi、Matsushima Kouji
    • Journal Title

      Sci Rep.

      Volume: 9 Pages: 1-12

    • DOI

      10.1038/s41598-019-40237-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-16K08730, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H01540
  • [Journal Article] First-in-human phase 1 study of IT1208, a defucosylated humanized anti-CD4 depleting antibody, in patients with advanced solid tumors2019

    • Author(s)
      Shitara K、Ueha S、Shichino S、Aoki H、Ogiwara H、Nakatsura T、Suzuki T、Shimomura M、Yoshikawa T、Shoda K、Kitano S、Yamashita M、Nakayama T、Sato A、Kuroda Sakiko、Wakabayashi Masashi、Nomura Shogo、Yokochi Shoji、Ito Satoru、Matsushima Kouji、Doi Toshihiko
    • Journal Title

      Journal for ImmunoTherapy of Cancer

      Volume: 7 Pages: 195-195

    • DOI

      10.1186/s40425-019-0677-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Journal Article] Gli signaling pathway modulates fibroblast activation and facilitates scar formation in pulmonary fibrosis.2019

    • Author(s)
      Tsukui Tatsuya、Ueha Satoshi、Shichino Shigeyuki、Hashimoto Shinichi、Nakajima Takuya、Shiraishi Kazushige、Kihara Miho、Kiyonari Hiroshi、Inagaki Yutaka、Matsushima Kouji
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 514 Pages: 30879-4

    • DOI

      10.1016/j.bbrc.2019.05.011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22627, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-17H04166, KAKENHI-PROJECT-17H01540
  • [Journal Article] Reduction of proliferating olfactory cells and low expression of extracellular matrix genes are hallmarks of the aged olfactory mucosa2018

    • Author(s)
      Ueha R, Shichino S, Ueha S, Kondo K, Kikuta S, Nishijima H, Matsushima K, Yamasoba T.
    • Journal Title

      Frontiers in Aging Neuroscience

      Volume: 10 Pages: 1-13

    • DOI

      10.3389/fnagi.2018.00086

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08730, KAKENHI-PROJECT-17K19546, KAKENHI-PROJECT-16K20231, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-15F15113, KAKENHI-PROJECT-17K11353, KAKENHI-PROJECT-18K09341, KAKENHI-PROJECT-18KK0448, KAKENHI-PROJECT-15K20185, KAKENHI-PROJECT-18K16832
  • [Journal Article] Lung fibroblasts express a miR-19a-19b-20a sub-cluster to suppress TGF-β-associated fibroblast activation in murine pulmonary fibrosis2018

    • Author(s)
      Souma Kunihiko、Shichino Shigeyuki、Hashimoto Shinichi、Ueha Satoshi、Tsukui Tatsuya、Nakajima Takuya、Suzuki Hiroshi I.、Shand Francis H. W.、Inagaki Yutaka、Nagase Takahide、Matsushima Kouji
    • Journal Title

      Scientific Reports

      Volume: 8 Pages: 1-14

    • DOI

      10.1038/s41598-018-34839-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-17H04166, KAKENHI-PROJECT-16K08730, KAKENHI-PROJECT-17K19546
  • [Journal Article] Long-lasting graft-Derived Donor T cells contribute to the Pathogenesis of chronic graft-versus-host Disease in Mice.2017

    • Author(s)
      Kosugi-Kanaya M, Ueha S, Abe J, Shichino S, Shand FHW, Morikawa T, Kurachi M, Shono Y, Sudo N, Yamashita A, Suenaga F, Yokoyama A, Yong W, Imamura M, Teshima T, Matsushima K.
    • Journal Title

      Front Immunol

      Volume: 8 Pages: 1842-1842

    • DOI

      10.3389/fimmu.2017.01842

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08730, KAKENHI-PROJECT-17K19546, KAKENHI-PROJECT-17K19641, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-17H04206, KAKENHI-PROJECT-15F15113
  • [Journal Article] Simian Immunodeficiency Virus Targeting of CXCR3+CD4+T Cells in Secondary Lymphoid Organs Is Associated with Robust CXCL10 Expression in Monocyte/Macrophage Subsets2017

    • Author(s)
      Fujino, M., H. Sato, T. Okamura, A. Uda, S. Takeda, N. Ahmed, S. Shichino, T. Shiino, Y. Saito, S. Watanabe, C. Sugimoto, M. Kuroda, M. Ato, Y. Nagai, S. Izumo, K. Matsushima, M. Miyazawa, A. Ansari, F. Villinger, and K. Mori
    • Journal Title

      J Virol

      Volume: 印刷中

    • DOI

      10.1128/jvi.00439-17

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01268, KAKENHI-PROJECT-15K10043, KAKENHI-PROJECT-17K19546, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-16H05199, KAKENHI-PROJECT-16H05203
  • [Patent] ビーズ担体を用いたcDNA増幅方法2019

    • Inventor(s)
      松島 綱治, 七野 成之、青木 寛泰、伊藤 哲、上羽 悟史
    • Industrial Property Rights Holder
      松島 綱治, 七野 成之、青木 寛泰、伊藤 哲、上羽 悟史
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2019-129017
    • Filing Date
      2019
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] 肺線維症のsingle cell transcriptome解析に基づく治療標的候補分子探索2021

    • Author(s)
      七野成之
    • Organizer
      ゲノム創薬・創発フォーラム第5回シンポジウム
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] 肺線維症のsingle cell transcriptome解析に基づく治療標的候補分子探索2021

    • Author(s)
      七野 成之
    • Organizer
      ゲノム創薬・創発フォーラム第5回シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K16620
  • [Presentation] シングルセルトランスクリプトーム解析の現状と、それに基づく肺線維症治療標的候補分子探索2021

    • Author(s)
      七野成之
    • Organizer
      第20回分子予防環境医学研究会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] シングルセルトランスクリプトーム解析の現状と、それに基づく肺線維症治療標的候補分子探索2021

    • Author(s)
      七野 成之
    • Organizer
      第20回分子予防環境医学研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K16620
  • [Presentation] 1細胞遺伝子発現解析から観る腫瘍浸潤樹状細胞の多様性2020

    • Author(s)
      上羽悟史, 七野成之, 小川達郎, 荻原春, 松島綱治
    • Organizer
      第24回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] 新規single-cell RNA-seq解析法TAS-Seqを用いた肺線維症における細胞間相互作用ネットワークにおけるハブ因子の同定2020

    • Author(s)
      七野 成之
    • Organizer
      第43回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K16620
  • [Presentation] 新規single-cell RNA-seq解析を用いた肺線維症における脂質代謝関連遺伝子変動とその役割の解析2020

    • Author(s)
      七野 成之
    • Organizer
      第93回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K16620
  • [Presentation] 新規single-cell RNA-seq解析法TAS-Seqを用いた肺線維症における細胞間相互作用ネットワークにおけるハブ因子の同定2020

    • Author(s)
      七野成之
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] 新規single-cell RNA-seq解析を用いた肺線維症における脂質代謝関連遺伝子変動とその役割の解析2020

    • Author(s)
      七野成之
    • Organizer
      第93回日本生化学会大会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] 末梢血-腫瘍間で重複するTCRレパトアは、消化器癌患者に対するPD-1阻害療法の有効性を予測しうる2020

    • Author(s)
      青木寛泰, 上羽悟史, 中村能章, 七野成之, 中島裕理, 下村真菜美, 中面哲也, 吉野孝之, 松島綱治
    • Organizer
      第24回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] Anti CD4 Monoclonal Antibody Immunotherapy Exerts an Antitumor Effect by Replacing the T Cell Receptor Repertoire in Patients with Gastrointestinal Cancer.2019

    • Author(s)
      Aoki H, Shitara K、Ueha S、Shichino S、Ogiwara H、Nakatsura T、Suzuki T、Shimomura M、Yoshikawa T、Shoda K、Kitano S、Yamashita M、Nakayama T、Sato A、Kuroda Sakiko、Wakabayashi Masashi、Nomura Shogo、Yokochi Shoji、Ito Satoru、Matsushima Kouji、Doi Toshihiko
    • Organizer
      AACR Annual Meeting 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] 担がん患者における抗CD4抗体投与後のTCRレパトア変動2019

    • Author(s)
      青木寛泰, 上羽悟史, 七野成之, 荻原春, 設樂紘平, 中面哲也, 鈴木利宙, 下村真菜美, 北野滋久, 山下万貴子, 伊藤哲, 土井俊彦, 松島綱治
    • Organizer
      第28回日本癌病態治療研究会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] ブレオマイシン誘導マウス肺線維症モデルにおける経時的1細胞トランスクリプトーム解析.2019

    • Author(s)
      七野成之, 橋本真一, 上羽悟史, 松島綱治.
    • Organizer
      第18回分子予防環境医学研究会大会
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] 肺におけるデコリン陽性線維芽細胞の局在と線維化に対する予防効果2019

    • Author(s)
      中島拓弥, 七野成之, 上羽悟史, 松島綱治
    • Organizer
      第40回日本炎症・再生医学会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] 新規高感度包括的1細胞トランスクリプトーム法の開発と線維化肺における解析2019

    • Author(s)
      七野成之, 橋本真一, 上羽悟史, 北畠正大, 伊藤利洋, 松島綱治
    • Organizer
      第5回骨免疫学会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] Mesenchymal-epithelial interactome analysis during alveologenesis revealed essential factors required for fibroblast-free mouse alveolosphere formation and human alveolar type 2 cell monoculture2019

    • Author(s)
      Kazushige Shiraishi, Shigeyuki Shichino, Takuya Nakajima, Satoshi Ueha, Shinichi Hashimoto, Satoshi Yamazaki, Kouji Matsushima
    • Organizer
      Gordon Research Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] マウス肺線維症モデルへの移入ルートおよびドナーによる移入効率と治療効果の解析2019

    • Author(s)
      中島拓弥・七野成之・上羽悟史・松島綱治
    • Organizer
      第18回分子予防環境医学研究会大会
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] TCR sequencing reveals the generation and expansion of tumor-specific CD8+T cell clones after anti-CD4 antibody treatment in tumor-bearing mice2018

    • Author(s)
      Satoshi Ueha, Aoki Hiroyasu, Shigeyuki Shichino, Ogiwara Haru, Shinichi Hashimoto, Kazuhiro Kakimi, Kouji Matsushima
    • Organizer
      Keystone Symposia
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] Single-cell transcriptome identifies cytokine/chemokine expression signatures of lung cell subsets in murine pulmonary fibrosis2018

    • Author(s)
      Shigeyuki Shichino, Shin-ichi Hashimoto, Satoshi Ueha, Kouji Matsushima.
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] マウス肺線維症モデルへの間葉系幹細胞の移入ルートおよびドナーによる移入効率と治療効果の解析2018

    • Author(s)
      中島拓弥・七野成之・上羽悟史・松島綱治
    • Organizer
      第39回日本炎症・再生医学会
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] Single-cell transcriptomeによるマウス線維化肺のサイト カイン・ケモカイン発現プロファイルの解明2018

    • Author(s)
      七野成之, 橋本真一, 上羽悟史, 松島綱治
    • Organizer
      第83回日本インターフェロン・サイトカイン学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] TCR sequencing reveals the generation and expansion of tumor-specific CD8+T cell clones after anti-CD4 antibody treatment in tumor-bearing mice2018

    • Author(s)
      Satoshi Ueha, Aoki Hiroyasu, Shigeyuki Shichino, Ogiwara Haru, Shinichi Hashimoto, Kazuhiro Kakimi, Kouji Matsushima
    • Organizer
      Keystone Symposia
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] 担がんマウスにおけるCD8+ T細胞レパトアの臓器別解析2018

    • Author(s)
      七野 成之, 青木 寛泰, 橋本 真一, 荻原 春, 上羽 悟史, 松島 綱治
    • Organizer
      第17回分子予防環境医学研究会大会
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] 細胞と分子の動きから観る臓器線維化2018

    • Author(s)
      七野 成之, 津久井 達也, 橋本 真一, 大辻 幹哉, 上羽 悟史, 稲垣 豊, 島野 仁, 松島 綱治
    • Organizer
      「炎症の慢性化機構の解明と制御に向けた基盤技術の創出」研究開発領域公開シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] An organ-wide transcriptome of stromal cells identifies the core signature of steady-state murine fibroblasts2017

    • Author(s)
      Shigeyuki SHICHINO, Satoshi UEHA, Shin-ichi HASHIMOTO, Inagaki YUTAKA, Kouji MATSUSHIMA
    • Organizer
      4th Lymphoid tissue meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] TCR sequencing reveals the generation and expansion of tumor-specific CD8+ T cell clones after anti-CD4 antibody treatment in tumor-bearing mice2017

    • Author(s)
      Satoshi Ueha, Yasuhiro Aoki, Shigeyuki Shichino, Haru Ogiwara, Shinichi Hashimoto, Kazuhiro Kakimi, Satoru Ito, Kouji Matsushima
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] TCR sequencing reveals the generation and expansion of tumor-specific CD8+T cell clones after anti-CD4 antibody treatment in tumor-bearing mice2017

    • Author(s)
      Satoshi Ueha, Aoki Hiroyasu, Shigeyuki Shichino, Ogiwara Haru, Shinichi Hashimoto, Kazuhiro Kakimi, Kouji Matsushima
    • Organizer
      The 46th Japanese Society for Immunology
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] 担がんマウスにおけるCD8+ T細胞レパトアの臓器別解析2017

    • Author(s)
      青木 寛泰、七野 成之、橋本 真一、上羽 悟史、松島 綱治
    • Organizer
      第3回日本骨免疫学会
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] TCR sequencing reveals the generation and expansion of tumor-specific CD8+ T cell clones after anti-CD4 antibody treatment in tumor-bearing mice2017

    • Author(s)
      Satoshi Ueha, Yasuhiro Aoki, Shigeyuki Shichino, Haru Ogiwara, Shinichi Hashimoto, Kazuhiro Kakimi, Satoru Ito, Kouji Matsushima
    • Organizer
      第21回日本がん免疫学会総会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] Transcriptome analysis reveals PDGF signaling-dependent regulation of myelofibrosis in murine chronic graft-versus-host diseases2017

    • Author(s)
      Shigeyuki Shichino, Satoshi Ueha, Naoto Sudo, Mizuha Kosugi-Kanaya, Francis HW Shand, Teppei Morikawa, Shin-ichi Hashimoto, Takanori Teshima, Kouji Matsushima
    • Organizer
      5th Annual Meeting of the International Cytokine and Interferon Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] 担がんマウスにおけるCD8+ T細胞レパトアの臓器別解析2017

    • Author(s)
      青木 寛泰、七野 成之、橋本 真一、上羽 悟史、松島 綱治
    • Organizer
      第3回日本骨免疫学会
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] Identification of a functional and transcriptional signature for tumor-infiltrating dendritic cells in mouse2017

    • Author(s)
      Satoshi Ueha, Haru Ogiwara, Shigeyuki Shichino, Jun Abe, Francis Shand, Shinichi Hashimoto, Kouji Matsushima
    • Organizer
      5th Annual Meeting of the International Cytokine and Interferon Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] Transcriptome network analysis reveals lipid-related transcription factors as hubs for fibroblast activation in murine pulmonary fibrosis2017

    • Author(s)
      Shigeyuki Shichino, Satoshi Ueha, Inagaki Yutaka, Shin-ichi Hashimoto, Hitoshi Shimano, and Kouji Matsushima
    • Organizer
      The 19th Takeda Science Foundation Symposium on Bioscience : Chronic Inflammation - initiation, Progression and Resolution
    • Place of Presentation
      武田薬品研修所(大阪府吹田市)
    • Year and Date
      2017-01-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] TCR sequencing reveals the generation and expansion of tumor-specific CD8+ T cell clones after anti-CD4 antibody treatment in tumor-bearing mice2017

    • Author(s)
      Satoshi Ueha, Yasuhiro Aoki, Shigeyuki Shichino, Haru Ogiwara, Shinichi Hashimoto, Kazuhiro Kakimi, Satoru Ito, Kouji Matsushima
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] 肺線維症における活性化線維芽細胞の起源とその活性化制御機構2017

    • Author(s)
      七野 成之, 上羽 悟史, 橋本 真一, 松島 綱治
    • Organizer
      第38回日本炎症・再生医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] Identification of a functional and transcriptional signature for tumor-infiltrating dendritic cells in mouse2017

    • Author(s)
      Satoshi Ueha, Haru Ogiwara, Shigeyuki Shichino, Jun Abe, Francis Shand, Shinichi Hashimoto, Kouji Matsushima
    • Organizer
      5th Annual Meeting of the International Cytokine and Interferon Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06392
  • [Presentation] TCR sequencing reveals the generation and expansion of tumor-specific CD8+ T cell clones after anti-CD4 antibody treatment in tumor-bearing mice2017

    • Author(s)
      Satoshi Ueha, Yasuhiro Aoki, Shigeyuki Shichino, Haru Ogiwara, Shinichi Hashimoto, Kazuhiro Kakimi, Satoru Ito, Kouji Matsushima
    • Organizer
      第21回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] 慢性GVHDにおける骨髄線維化の分子メカニズムの検討2017

    • Author(s)
      七野 成之, 上羽 悟史, 須藤 直人、小杉 瑞葉, 松島 綱治
    • Organizer
      第3回日本骨免疫学会
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] TCR sequencing reveals the generation and expansion of tumor-specific CD8+T cell clones after anti-CD4 antibody treatment in tumor-bearing mice2017

    • Author(s)
      Satoshi Ueha, Aoki Hiroyasu, Shigeyuki Shichino, Ogiwara Haru, Shinichi Hashimoto, Kazuhiro Kakimi, Kouji Matsushima
    • Organizer
      The 46th Japanese Society for Immunology
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] 肺線維症における細胞動態2016

    • Author(s)
      上羽悟史、津久井達哉、七野成之、松島綱治
    • Organizer
      第40回日本リンパ学会総会
    • Place of Presentation
      東京大学伊藤国際学術研究センター(東京都文京区)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] 多臓器間網羅的トランスクリプトーム解析による線維芽細胞 core transcriptomic signatureの同定2016

    • Author(s)
      七野成之, 上羽悟史, 橋本真一, 松島綱治
    • Organizer
      第2回日本骨免疫学会
    • Place of Presentation
      ホテルモントレ沖縄スパ&リゾート(沖縄県国頭郡)
    • Year and Date
      2016-07-06
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] Intravascular staining identifies tissue compartment of myeloid cell subsets in fibrotic and cancer-bearing murine lungs2016

    • Author(s)
      Shigeyuki Shichino, Francis HW Shand, Satoshi Ueha, and Kouji Matsushima
    • Organizer
      第24回マクロファージ分子細胞生物学国際シンポジウム
    • Place of Presentation
      御茶ノ水ソラシティカンファレンスセンター(東京都千代田区)
    • Year and Date
      2016-06-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] Macrophage regulation of inflammation and tissue remodeling in pulmonary fibrosis2016

    • Author(s)
      Satoshi Ueha, Shigeyuki Shichino, Kouji Matsushima
    • Organizer
      第89回生化学会大会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-09-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05203
  • [Presentation] An organ-wide transcriptome of collagen-producing cells identifies the core signature of steady-state murine fibroblasts2016

    • Author(s)
      "Shigeyuki SHICHINO, Satoshi UEHA, Shin-ichi HASHIMOTO, Inagaki YUTAKA and Kouji MATSUSHIMA"
    • Organizer
      第45回日本免疫学会学術集会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄県宜野湾市)
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-16H05203
  • 1.  上羽 悟史 (00447385)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 48 results
  • 2.  Matsushima Kouji (50222427)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 54 results
  • 3.  橋本 真一 (00313099)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 32 results
  • 4.  伊藤 利洋 (00595712)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 5.  島岡 猛士 (90422279)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  山野 荘太郎 (80614528)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  杉原 英志 (50464996)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  Nakajima Takuya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 9.  Aoki Hiroyasu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 10.  INAGAKI Yutaka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 11.  YAMASHITA Makiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  OGURA Atsushi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  IWATA Yasunori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  FURUICHI Kengo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  WADA Takashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  FUJINO Masayuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  島野 仁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  韓 松伊
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  山崎 聡
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  上羽 瑠美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  近藤 健二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  菊田 周
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  西嶌 大宣
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  豊嶋 崇徳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  SHAND FRANCIS
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 26.  池尾 一穂
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  坂井 宣彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  宮澤 正顕
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  梨井 康
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  森 一泰
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  赤羽 悟美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  西山 千春
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  中野 裕康
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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