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Sekii Yosuke  関井 洋輔

ORCIDConnect your ORCID iD *help
Researcher Number 70824770
Other IDs
Affiliation (Current) 2025: 大阪大学, 大学院医学系研究科, 招へい教員
Affiliation (based on the past Project Information) *help 2022 – 2023: 大阪大学, 大学院医学系研究科, 招へい教員
2019 – 2021: 大阪大学, 医学部附属病院, 医員
Review Section/Research Field
Principal Investigator
Basic Section 56030:Urology-related
Except Principal Investigator
Basic Section 56030:Urology-related
Keywords
Principal Investigator
マウス / 動物モデル / 夜間多尿 / 水素 / 酸化ストレス / シリコンナノ粒子 / 活性酸素 / 高血圧 / 新規動物モデル / 時計遺伝子 … More / 夜間多尿動物モデル / 遠位尿細管 / NCC / nitric oxide / Naトランスポーター / 塩分 … More
Except Principal Investigator
一酸化窒素 / 夜間多尿 Less
  • Research Projects

    (3 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (6 People)
  •  酸化ストレスが夜間多尿に与える影響と新規治療ターゲットの探索Principal Investigator

    • Principal Investigator
      関井 洋輔
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Osaka University
  •  The impact of exercise on nocturnal polyuria and the development of therapeutic strategies based on the pathophysiology

    • Principal Investigator
      Kiuchi Hiroshi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Osaka University
  •  Exploration of therapeutic strategies for nocturnal polyuria using a novel animal modelPrincipal Investigator

    • Principal Investigator
      Sekii Yosuke
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Osaka University

All 2022 2021 2020

All Journal Article Presentation Book

  • [Book] 排尿障害プラクティス2021

    • Author(s)
      関井洋輔
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-19K18582
  • [Journal Article] Dietary salt with nitric oxide deficiency induces nocturnal polyuria in mice via hyperactivation of intrarenal angiotensin II-SPAK-NCC pathway2022

    • Author(s)
      Y. Sekii, H. Kiuchi, K. Takezawa, T. Imanaka, S. Kuribayashi, K. Okada, Y. Inagaki, N. Ueda, S. Fukuhara, R. Imamura, H. Negoro & N. Nonomura
    • Journal Title

      Communications Biololgy

      Volume: 5 Issue: 1 Pages: 175-175

    • DOI

      10.1038/s42003-022-03104-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K18582
  • [Journal Article] Decreased renal function increases the nighttime urine volume rate by carryover of salt excretion to the nighttime2021

    • Author(s)
      Kentaro Takezawa , Sohei Kuribayashi , Koichi Okada , Yosuke Sekii , Yusuke Inagaki , Shinichiro Fukuhara , Hiroshi Kiuchi , Toyofumi Abe , Kazutoshi Fujita , Motohide Uemura , Ryoichi Imamura , Norio Nonomura
    • Journal Title

      Scientific reports

      Volume: 11 Issue: 1 Pages: 10587-10587

    • DOI

      10.1038/s41598-021-90166-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K18582
  • [Presentation] Oxidative stress drives nocturnal polyuria via intrarenal SPAK-NCC pathway: a therapeutic potential of a novel antioxidant, Silicon component agents.2022

    • Author(s)
      Yosuke Sekii
    • Organizer
      AUA2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K16789
  • [Presentation] シリコン成分剤は加齢に伴う腎の酸化ストレスを軽減しマウスの夜間多尿を改善させる新規治療法となりうる2022

    • Author(s)
      関井 洋輔
    • Organizer
      JUA2022
    • Data Source
      KAKENHI-PROJECT-22K16789
  • [Presentation] シリコン成分剤は加齢に伴う腎の酸化ストレスを軽減しマウスの夜間多尿を改善させる新規治療法となりうる.2021

    • Author(s)
      関井洋輔、竹澤健太郎、今中岳洋、栗林宗平、 岡田紘一、福原慎一郎、 木内 寛、植村元秀、今村亮一、小林悠輝、小林 光、野々村祝夫
    • Organizer
      2021年日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-19K18582
  • [Presentation] 新規夜間多尿動物モデルを用いた夜間多尿の病態解明:腎臓内RAS系-SPAK-NCC経路の過剰活性化によるナトリウム排泄抑制が夜間多尿をひきおこす2021

    • Author(s)
      関井 洋輔 ,竹澤 健太郎 ,今中 岳洋 ,栗林 宗平 ,岡田 紘一 ,稲垣 裕介 ,福原 慎一郎 ,木内 寛 ,野々村 祝夫
    • Organizer
      2021年日本排尿機能学会学会賞受賞
    • Data Source
      KAKENHI-PROJECT-19K18582
  • [Presentation] New insights into the molecular mechanisms of nocturnal polyuria using a novel animal model: Insufficient sodium excretion by hyperactivation of the renal RAS-SPAK-NCC pathway causes nocturnal polyuria2021

    • Author(s)
      Sekii Y, Takezawa K, Imanaka T, Kuribayashi S, Okada K, Fukuhara S, Kiuchi H, Nonomura N
    • Organizer
      2021年International Continence Society best non-clinical award および2021年日本排尿機能学会河邊賞受賞
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K18582
  • [Presentation] The Firmicutes/Bacteroidetes ratio of the gut microbiota is associated with prostate enlargement. Takezawa K, Imanaka T, Kuribayashi S, Okada K, Sekii Y, Fukuhara S, Kiuchi H, Nonomura N2021

    • Author(s)
      Takezawa K, Imanaka T, Kuribayashi S, Okada K, Sekii Y, Fukuhara S, Kiuchi H, Nonomura N
    • Organizer
      2021年日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-19K18582
  • [Presentation] アルドステロン過剰状態が下部尿路症状へ与える影響2020

    • Author(s)
      関井洋輔
    • Organizer
      日本排尿機能学会
    • Data Source
      KAKENHI-PROJECT-19K18582
  • [Presentation] 塩分摂取が夜間多尿に与える影響は高血圧患者と正常血圧患者で異なる2020

    • Author(s)
      関井洋輔
    • Organizer
      日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-19K18582
  • 1.  Kiuchi Hiroshi (70403053)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  岡田 紘一 (30845194)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  稲垣 裕介 (80804400)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  竹澤 健太郎 (90648015)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  福原 慎一郎 (20609870)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  野々村 祝夫 (30263263)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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