KAWAI TOMOKO 川合智子

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川合智子カワイトモコ

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Researcher Number	70839654
Other IDs	https://orcid.org/0009-0006-5130-8728
Affiliation (Current)	2025: 岡山大学, 医歯薬学域, 助教
Affiliation (based on the past Project Information) *help	2024: 岡山大学, 医歯薬学域, 助教 2021: 広島大学, 統合生命科学研究科(生), 助教 2013 – 2014: 広島大学, 生物圏科学研究科, 特別研究員(DC2)
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Applied animal science / Basic Section 42010:Animal production science-related
Keywords	Principal Investigator レチノイン酸 / 受精 / 精子機能 / 不妊症 / 副交感神経系 / DNAメチル化 / 細胞分化 / エピジェネティック / 卵成熟 / LH受容体 … More / 卵胞発育 / 胚性ゲノム / 受精卵 / 胚性因子 / 母性因子 / 発生運命 / 母体栄養 Less

Elucidation of the regulatory mechanism of sperm motility and fertility by the parasympathetic nervous and the demonstration using a sperm culture systemPrincipal Investigator
- Principal Investigator
  
  川合智子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Okayama University
新規母性レチノールと胚性レチノイン酸合成系による受精卵の発生運命決定機構の解明Principal Investigator
- Principal Investigator
  
  川合智子
- Project Period (FY)
  2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Hiroshima University
アセトアルデヒド脱水素酵素群の基質選択性に着目した卵胞発育機構の分子内分泌的解析Principal Investigator
- Principal Investigator
  
  川合智子
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Applied animal science
- Research Institution
  Hiroshima University

All 2021 2020 2014 Other

All Journal Article Presentation

[Journal Article] Large-scale DNA demethylation occurs in proliferating ovarian granulosa cells during mouse follicular development.2021
- Author(s)
  Kawai T, Richards JS, Shimada M.
- Journal Title
  
  Commun Biol.
  
  Volume: 4 Issue: 1 Pages: 1334-1334
- DOI
  10.1038/s42003-021-02849-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K14961, KAKENHI-PROJECT-19H03108
[Journal Article] Adverse effect of superoxide-induced mitochondrial damage in granulosa cells on follicular development in mouse ovaries.2020
- Author(s)
  Hoque SAM, Umehara T, Kawai T, Shimada M
- Journal Title
  
  Free Radic Biol Med.
  
  Volume: 163 Pages: 344-355
- DOI
  10.1016/j.freeradbiomed.2020.12.434
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03108, KAKENHI-PROJECT-21K14961
[Journal Article] Targeted disruption of Nrg1 in granulosa cells alters the temporal progression of oocyte maturation.2014
- Author(s)
  Kawashima I, Umehara T, Noma N, Kawai T, Shitanaka M, Richards JS, Shimada M.
- Journal Title
  
  Mol Endocrinol.
  
  Volume: 28(5) Pages: 706-721
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J02153
[Presentation] ミトコンドリア活性化による酸化ストレスが2細胞期胚停止を引きおこす.2021
- Author(s)
  川合智子、川島千佳、島田昌之.
- Organizer
  第39回日本受精着床学会
- Data Source
  KAKENHI-PROJECT-21K14961
[Presentation] 卵胞発育期におけるLhcgrプロモーター領域脱メチル化の排卵に果たす生理的意義
- Author(s)
  川合智子, 島田昌之.
- Organizer
  第8回生殖細胞の会
- Place of Presentation
  千葉
- Year and Date
  2014-11-06 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-13J02153
[Presentation] 卵胞発育期におけるLH 受容体発現のレチノイン酸を介したエピジェネティック制御機構
- Author(s)
  川合智子, 島田昌之.
- Organizer
  第32回日本受精着床学会
- Place of Presentation
  東京
- Year and Date
  2014-07-31 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-13J02153
[Presentation] Retinoic acid regulates methylation of the promoter and expression of Lhcgr granulosa cells during follicular development.
- Author(s)
  Tomoko Kawai, Noriyuki Yanaka, Yasuhisa Yamashita, JoAnne S. Richards, Masayuki Shimada.
- Organizer
  The Society for the Study of Reproduction
- Place of Presentation
  Michigan, USA
- Year and Date
  2014-07-19 – 2014-07-23
- Data Source
  KAKENHI-PROJECT-13J02153

1. 島田昌之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAWAI TOMOKO 川合 智子

川合 智子 カワイ トモコ

Research Projects

Research Products

Co-Researchers

Elucidation of the regulatory mechanism of sperm motility and fertility by the parasympathetic nervous and the demonstration using a sperm culture systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新規母性レチノールと胚性レチノイン酸合成系による受精卵の発生運命決定機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

アセトアルデヒド脱水素酵素群の基質選択性に着目した卵胞発育機構の分子内分泌的解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Large-scale DNA demethylation occurs in proliferating ovarian granulosa cells during mouse follicular development.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Adverse effect of superoxide-induced mitochondrial damage in granulosa cells on follicular development in mouse ovaries.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Targeted disruption of Nrg1 in granulosa cells alters the temporal progression of oocyte maturation.2014

Author(s)

Journal Title

Data Source

[Presentation] ミトコンドリア活性化による酸化ストレスが2細胞期胚停止を引きおこす.2021

Author(s)

Organizer

Data Source

[Presentation] 卵胞発育期におけるLhcgrプロモーター領域脱メチル化の排卵に果たす生理的意義

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 卵胞発育期におけるLH 受容体発現のレチノイン酸を介したエピジェネティック制御機構

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Retinoic acid regulates methylation of the promoter and expression of Lhcgr granulosa cells during follicular development.

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

KAWAI TOMOKO 川合智子

川合智子カワイトモコ