ARAI SHINPEI 新井慎平

… Alternative Names

Arai Shinpei 新井慎平

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Researcher Number	70866053
Other IDs
Affiliation (Current)	2025: 信州大学, 学術研究院保健学系, 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 信州大学, 学術研究院保健学系, 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related Except Principal Investigator Basic Section 52010:General internal medicine-related
Keywords	Principal Investigator フィブリン重合反応 / フィブリノゲン蓄積病 / フィブリノゲン / Ca動態 / リコンビナントタンパク / フォールディング異常 / 先天性フィブリノゲン異常症 / セルスタック / ローラーボトル / 大量培養 … More / 免疫沈降 / 小胞体ストレス / ケミカルシャペロン / 小胞体ストレス応答 / 先天性フィブリノゲン低下症 … More Except Principal Investigator NETs / 形質転換能 / 遊走能 / 皮膚線維芽細胞 / 血管内皮細胞 / フィブリン / THP-1 / M1-マクロファージ / NETｓ形成能 / 好中球 / NETs形成能 / 内皮間葉転換能 / 細胞遊走能 / アミロイドβ1-42 / M1-Mφ分化 / 管状構造形成能 / 異常フィブリノゲン / フィブリノゲン Less

フィブリノゲンの重合機能部位の異常に着目したフィブリノゲン蓄積病の病態解明Principal Investigator
- Principal Investigator
  
  新井慎平
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Shinshu University
Analysis of fibrinogen function and storage kinetics using model cells of fibrinogen storage diseasePrincipal Investigator
- Principal Investigator
  
  Arai Shinpei
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Shinshu University
Evaluation for extra-cellular function of dysfunctional fibrinogen and identification of its important residues
- Principal Investigator
  
  Okumura Nobuo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Shinshu University

All 2023 2022 2021 2020

All Journal Article Presentation Book

[Book] 日本血栓止血学会誌【特集：凝固波形解析（CWA）のアップデート】凝固波形解析によるフィブリノゲン異常の検査診断2023
- Author(s)
  新井慎平、奥村伸生
- Total Pages
  7
- Publisher
  日本血栓止血学会
- Data Source
  KAKENHI-PROJECT-21K15945
[Book] 臨床検査【検査血液学レッスン　検査結果の乖離をどう判断するか】(4章)凝固　フィブリノゲンの偽低値　IgA M蛋白血症2022
- Author(s)
  新井慎平
- Total Pages
  4
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-21K15945
[Journal Article] フィブリノゲン異常症を背景とした包括的高度慢性下肢虚血の治療経験2023
- Author(s)
  水島大地, 水島大地, 多田裕樹, 多田裕樹, 新井慎平, 吉田正宏, 小林大太, 菊地信介, 東信良, 赤坂伸之
- Journal Title
  
  血管外科
  
  Volume: 42巻 Pages: 61-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15945
[Journal Article] Laboratory diagnosis of fibrinogen disorder using clot waveform analysis2023
- Author(s)
  新井慎平、奥村伸生
- Journal Title
  
  Japanese Journal of Thrombosis and Hemostasis
  
  Volume: 34 Issue: 1 Pages: 22-28
- DOI
  10.2491/jjsth.34.22
- ISSN
  0915-7441, 1880-8808
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07799
[Journal Article] フィブリノゲンの偽低値　IgA M蛋白血症2022
- Author(s)
  新井慎平
- Journal Title
  
  臨床検査
  
  Volume: 66 Pages: 1236-1239
- Data Source
  KAKENHI-PROJECT-20K07799
[Journal Article] Screening method for congenital dysfibrinogenemia and hypodysfibrinogenemia using clot waveform analysis with the Clauss method2021
- Author(s)
  Arai S, Kamijo T, Hayashi F, Shinohara S, Arai N, Sugano M, Uehara T, Honda T, Okumura N.
- Journal Title
  
  Int J Lab Hematol
  
  Volume: 43 Issue: 2 Pages: 281-289
- DOI
  10.1111/ijlh.13358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07799, KAKENHI-PROJECT-21K15945
[Journal Article] Automated screening procedure for phenotype of congenital fibrinogen disorder using novel parameters, |min1|c and Ac/|min1|c obtained from clot waveform analysis of Clauss method2021
- Author(s)
  Arai S, Kamijo T, Kaido T, Yoda M, Shinohara S, Suzuki T, Arai N, Sugano M, Uehara T, Okumura N.
- Journal Title
  
  Clinica Chimica ACTA
  
  Volume: 521 Pages: 170-176
- DOI
  10.1016/j.cca.2021.07.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07799, KAKENHI-PROJECT-21K15945
[Journal Article] A novel variant fibrinogen, AαE11del, demonstrating the important of AαE11 residue in thrombin binding2021
- Author(s)
  Kaido T, Yoda M, Kamijo T, Arai S, Yamauchi K, Okumura N
- Journal Title
  
  Int J Hematology
  
  Volume: 114 Issue: 5 Pages: 591-598
- DOI
  10.1007/s12185-021-03200-z
- NAID
  120007180889
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07799, KAKENHI-PROJECT-21K07310, KAKENHI-PROJECT-21K15945
[Journal Article] 28年間で解析した長野県内のフィブリノゲン異常症18家系28例2021
- Author(s)
  上條途夢, 海藤貴大, 依田将宏, 平千明, 樋口由美子, 新井慎平, 竹澤由夏, 奥村伸生
- Journal Title
  
  長臨技会誌
  
  Volume: 10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15945
[Journal Article] 28年間で解析した長野県内のフィブリノゲン異常症18家系28例2021
- Author(s)
  上條途夢，海藤貴大, 依田将宏, 平千明,　樋口由美子，新井慎平,　竹澤由夏，奥村伸生．
- Journal Title
  
  長臨技会誌
  
  Volume: 10 Pages: 1-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07799
[Journal Article] Novel variant fibrinogen γ p.C352R produced hypodysfibrinogenemia leading to a bleeding episode and failure of infertility treatment2021
- Author(s)
  Yoda M, Kaido T, Kamijo T, Taira C, Higuchi Y, Arai S, Okumura N.
- Journal Title
  
  Int J Hematology
  
  Volume: 114 Issue: 3 Pages: 325-333
- DOI
  10.1007/s12185-021-03174-y
- NAID
  120007180888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07799, KAKENHI-PROJECT-21K15945
[Journal Article] Recombinant γY278H fibrinogen shows normal secretion from CHO cells, but a corresponding heterozygous patient showed hypofibrinogenemia2021
- Author(s)
  KamijoT, Kaido T, Yoda M, Arai S, Yamauchi K, Okumura N.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 22 Issue: 10 Pages: 5218-5218
- DOI
  10.3390/ijms22105218
- NAID
  120007180886
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07799, KAKENHI-PROJECT-21K07310, KAKENHI-PROJECT-21K15945
[Journal Article] Congenital fibrinogen disorder with a compound heterozygote possessing two novel FGB mutations, one qualitative and the other quantitative2020
- Author(s)
  Yoda M, Kaido T, Taira C, Higuchi Y, Arai S, Okumura N.
- Journal Title
  
  Thromb Res
  
  Volume: 196 Pages: 152-158
- DOI
  10.1016/j.thromres.2020.08.031
- NAID
  120007180892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07799
[Journal Article] A novel amino acid substitution, fibrinogen Bβp.Pro234Leu, associated with hypofibrinogenemia causing impairment of fibrinogen assembly and secretion2020
- Author(s)
  Kaido T, Yoda M, Kamijo T, Arai S, Taira C, Higuchi Y, Okumura N.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 21 Issue: 24 Pages: 9422-9422
- DOI
  10.3390/ijms21249422
- NAID
  120007180887
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07799
[Presentation] 異常フィブリノゲンが創傷治癒に及ぼす影響の解析とその評価法の検討2023
- Author(s)
  新井慎平, 上條途夢, 海藤貴大
- Organizer
  第70回日本臨床検査医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15945
[Presentation] フィブリノゲンによるマクロファージ分化誘導能評価系の構築2023
- Author(s)
  服部周生, 大下竜登, 新井慎平, 大谷ひかる, 市川友喜, 藤村哲士, 松田和之, 樋口由美子
- Organizer
  第70回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15945
[Presentation] γHis340Asp・γThr371Ile変異を有するフィブリノゲン蓄積病モデル細胞の解析2023
- Author(s)
  新井慎平, 海藤貴大
- Organizer
  第24回日本検査血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15945
[Presentation] 私のキャリアデザイン～臨床検査技師出身の教員として～2023
- Author(s)
  新井慎平
- Organizer
  第47回長野県臨床検査学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15945
[Presentation] 新規変異BβCys76Pheを伴った低フィブリノゲン血症の1症例2023
- Author(s)
  菅崎幹樹, 中村信元, 新井慎平, 漆原南実, 寺本継脩, 秦真公人, 井上雄介, 中尾隆之, 西岡安彦, 佐田政隆
- Organizer
  第24回日本検査血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15945
[Presentation] Novel approach for the phenotypes of congenital fibrinogen disorders using alternative fibrinogen value, |min1|c, obtained from clot waveform analysis2022
- Author(s)
  Shinpei Arai, Tomu Kamijo, Takahiro Kaido, Sho Shinohara, Takeshi Suzuki, Nobuo Arai, Takeshi Uehara, Nobuo Okumura
- Organizer
  The 17th Congress of Asian Society of Clinical Pathology and Laboratory Medicine（ASCPaLM）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15945
[Presentation] Novel approach for the phenotypes of congenital fibrinogen disorders using alternative fibrinogen value, |min1|c, obtained from clot waveform analysis2022
- Author(s)
  Shinpei Arai, Tomu Kamijo, Takahiro Kaido, Sho Shinohara, Takeshi Suzuki, Nobuo Arai, Takeshi Uehara, Nobuo Okumura
- Organizer
  The 17th Congress of Asian Society of Clinical Pathology and Laboratory Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07799
[Presentation] 先天性フィブリノゲン異常症の変異フィブリノゲンとアミロイドβの結合性の検討2021
- Author(s)
  新井慎平, 上條途夢, 海藤貴大
- Organizer
  第68回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15945
[Presentation] 先天性フィブリノゲン異常症の変異フィブリノゲンとアミロイドβの結合性の検討2021
- Author(s)
  新井慎平、上條途夢、海藤貴大
- Organizer
  第68回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07799
[Presentation] 凝固波形解析パラメーター|min1|から算出したフィブリノゲン値を用いた先天性フィブリノゲン異常症の検出2021
- Author(s)
  新井慎平, 竹澤由夏, 上條途夢, 海藤貴大, 篠原翔, 鈴木健史, 新井信夫, 上原剛, 奥村伸生
- Organizer
  第22回日本検査血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15945

1. Okumura Nobuo (60252110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
2. 樋口由美子 (40757241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. 平千明 (40779310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results

ARAI SHINPEI 新井 慎平

Arai Shinpei 新井 慎平

Research Projects

Research Products

Co-Researchers

フィブリノゲンの重合機能部位の異常に着目したフィブリノゲン蓄積病の病態解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of fibrinogen function and storage kinetics using model cells of fibrinogen storage diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Evaluation for extra-cellular function of dysfunctional fibrinogen and identification of its important residues

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 日本血栓止血学会誌【特集：凝固波形解析（CWA）のアップデート】凝固波形解析によるフィブリノゲン異常の検査診断2023

Author(s)

Total Pages

Publisher

Data Source

[Book] 臨床検査【検査血液学レッスン 検査結果の乖離をどう判断するか】(4章)凝固 フィブリノゲンの偽低値 IgA M蛋白血症2022

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] フィブリノゲン異常症を背景とした包括的高度慢性下肢虚血の治療経験2023

Author(s)

Journal Title

Data Source

[Journal Article] Laboratory diagnosis of fibrinogen disorder using clot waveform analysis2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] フィブリノゲンの偽低値 IgA M蛋白血症2022

Author(s)

Journal Title

Data Source

[Journal Article] Screening method for congenital dysfibrinogenemia and hypodysfibrinogenemia using clot waveform analysis with the Clauss method2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Automated screening procedure for phenotype of congenital fibrinogen disorder using novel parameters, |min1|c and Ac/|min1|c obtained from clot waveform analysis of Clauss method2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel variant fibrinogen, AαE11del, demonstrating the important of AαE11 residue in thrombin binding2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] 28年間で解析した長野県内のフィブリノゲン異常症18家系28例2021

Author(s)

Journal Title

Data Source

[Journal Article] 28年間で解析した長野県内のフィブリノゲン異常症18家系28例2021

Author(s)

Journal Title

Data Source

[Journal Article] Novel variant fibrinogen γ p.C352R produced hypodysfibrinogenemia leading to a bleeding episode and failure of infertility treatment2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Recombinant γY278H fibrinogen shows normal secretion from CHO cells, but a corresponding heterozygous patient showed hypofibrinogenemia2021

Author(s)

ARAI SHINPEI 新井慎平

Arai Shinpei 新井慎平

[Book] 臨床検査【検査血液学レッスン　検査結果の乖離をどう判断するか】(4章)凝固　フィブリノゲンの偽低値　IgA M蛋白血症2022

[Journal Article] フィブリノゲンの偽低値　IgA M蛋白血症2022