Yamashita Hitomi 山下瞳

… Alternative Names

山下瞳ヤマシタヒトミ

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Researcher Number	70869015
Other IDs
Affiliation (Current)	2025: 島根大学, 学術研究院医学・看護学系, 助教
Affiliation (based on the past Project Information) *help	2025: 島根大学, 学術研究院医学・看護学系, 助教 2022 – 2023: 島根大学, 学術研究院医学・看護学系, 助教
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related
Keywords	Principal Investigator 希少がん / 婦人科希少がん / オルガノイドライブラリー

子宮体癌におけるPARP阻害薬とICI併用療法の有効性と分子基盤の解明Principal Investigator
- Principal Investigator
  
  山下瞳
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Shimane University
婦人科希少がんオルガノイドライブラリーを基盤とした新規治療法の開発Principal Investigator
- Principal Investigator
  
  山下瞳
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Shimane University

All 2023 2022

All Journal Article Presentation

[Journal Article] The Case of an Endometrial Cancer Patient with Breast Cancer Who Has Achieved Long-Term Survival via Letrozole Monotherapy2023
- Author(s)
  Ishikawa M, Nakayama K, Razia S, Yamashita H, Ishibashi T, Haraga H, Kanno K, Ishikawa N, Kyo S.
- Journal Title
  
  Curr Issues Mol Biol.
  
  Volume: 45 Issue: 1 Pages: 2908-2916
- DOI
  10.1186/s12905-021-01302-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16860
[Journal Article] Promising Therapeutic Impact of Immune Checkpoint Inhibitors in TypeⅡ Endometrial Cancer Patients with Deficient Mismatch Repair Status.2023
- Author(s)
  Sawada K, Nakayama K, Razia S, Yamashita H, Ishibashi T, Ishikawa M, Kanno K, Sato S, Nakayama S, Otsuki Y, Kyo S.
- Journal Title
  
  Healthcare (Basel).
  
  Volume: 11 Issue: 8 Pages: 1073-1073
- DOI
  10.3390/healthcare11081073
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16860, KAKENHI-PROJECT-22K09596, KAKENHI-PROJECT-21K09472, KAKENHI-PROJECT-21K16793
[Journal Article] Identifying the Carcinogenic Mechanism of Malignant Struma Ovarii Using Whole-Exome Sequencing and DNA Methylation Analysis2023
- Author(s)
  Yamashita Hitomi、Nakayama Kentaro、Kanno Kosuke、Ishibashi Tomoka、Ishikawa Masako、Sato Seiya、Iida Koji、Razia Sultana、Kyo Satoru
- Journal Title
  
  Current Issues in Molecular Biology
  
  Volume: 45 Issue: 3 Pages: 1843-1851
- DOI
  10.3390/cimb45030118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16793, KAKENHI-PROJECT-22K16860, KAKENHI-PROJECT-22K09596, KAKENHI-PROJECT-21K09472
[Journal Article] Histological and Genetic Diversity in Ovarian Mucinous Carcinomas:A Pilot Study.2023
- Author(s)
  Razia S, Nakayama K, Yamashita H, Ishibashi T, Ishikawa M, Kanno K, Sato S, Kyo S.
- Journal Title
  
  Curr Oncol.
  
  Volume: 30 Issue: 4 Pages: 4052-4059
- DOI
  10.3390/curroncol30040307
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16860, KAKENHI-PROJECT-22K09596, KAKENHI-PROJECT-21K09472, KAKENHI-PROJECT-21K16793
[Journal Article] Ovarian Endometrioid and Clear Cell Carcinomas with Low Prevalence of Microsatellite Instability: A Unique Subset of Ovarian Carcinomas Could Benefit from Combination Therapy with Immune Checkpoint Inhibitors and Other Anticancer Agents2022
- Author(s)
  Nonomura Yuki、Nakayama Kentaro、Nakamura Kohei、Razia Sultana、Yamashita Hitomi、Ishibashi Tomoka、Ishikawa Masako、Sato Seiya、Nakayama Satoru、Otsuki Yoshiro、Kyo Satoru
- Journal Title
  
  Healthcare
  
  Volume: 10 Issue: 4 Pages: 694-694
- DOI
  10.3390/healthcare10040694
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18232, KAKENHI-PROJECT-22K09596, KAKENHI-PROJECT-22K16860
[Journal Article] Mutation Profiles of Ovarian Seromucinous Borderline Tumors in Japanese Patients2022
- Author(s)
  Sasamori Hiroki、Nakayama Kentaro、Razia Sultana、Yamashita Hitomi、Ishibashi Tomoka、Ishikawa Masako、Sato Seiya、Nakayama Satoru、Otsuki Yoshiro、Fujiwaki Ritsuto、Ishikawa Noriyoshi、Kyo Satoru
- Journal Title
  
  Current Oncology
  
  Volume: 29 Issue: 5 Pages: 3658-3667
- DOI
  10.3390/curroncol29050294
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09472, KAKENHI-PROJECT-22K09596, KAKENHI-PROJECT-21K16793, KAKENHI-PROJECT-22K16860
[Journal Article] 特集専攻医のうちにマスターしたい産婦人科の外来･短期滞在手術総論 1.外陰･腟･子宮頸部の局所解剖2022
- Author(s)
  山下瞳、京哲
- Journal Title
  
  産婦人科の実際
  
  Volume: 71 Issue: 4 Pages: 341-345
- DOI
  10.18888/sp.0000002103
- ISSN
  0558-4728
- Year and Date
  2022-04-01
- Data Source
  KAKENHI-PROJECT-22K16860
[Journal Article] Clinical Landscape of PARP Inhibitors in Ovarian Cancer: Molecular Mechanisms and Clues to Overcome Resistance2022
- Author(s)
  Kyo Satoru、Kanno Kosuke、Takakura Masahiro、Yamashita Hitomi、Ishikawa Masako、Ishibashi Tomoka、Sato Seiya、Nakayama Kentaro
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 10 Pages: 2504-2504
- DOI
  10.3390/cancers14102504
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09631, KAKENHI-PROJECT-21K09472, KAKENHI-PROJECT-22K09596, KAKENHI-PROJECT-21K16793, KAKENHI-PROJECT-22K16860
[Journal Article] Promising Therapeutic Impact of a Selective Estrogen Receptor Downregulator, Fulvestrant, as Demonstrated In Vitro upon Low-Grade Serous Ovarian Carcinoma Cell Lines2022
- Author(s)
  Shanta Kamrunnahar、Nakayama Kentaro、Hossain Mohammad Mahmud、Razia Sultana、Ishibashi Tomoka、Ishikawa Masako、Yamashita Hitomi、Kanno Kosuke、Sato Seiya、Nakayama Satoru、Otsuki Yoshiro、Kyo Satoru
- Journal Title
  
  Current Oncology
  
  Volume: 29 Issue: 6 Pages: 4020-4033
- DOI
  10.3390/curroncol29060321
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09472, KAKENHI-PROJECT-22K09596, KAKENHI-PROJECT-21K16793, KAKENHI-PROJECT-22K16860
[Presentation] Investigating the mechanism of resistance to PARP inhibitors: Genetic analysis of an ovarian cancer patient with germline BRCA1 variant who became resistant to PARP inhibitors2023
- Author(s)
  Hitomi Yamashita, Kentaro Nakayama, Hikaru Haraga, Tomoka Ishibashi, Masako Ishikawa, Koji Iida, Satoru Kyo
- Organizer
  第75回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-22K16860
[Presentation] Investigating the mechanism of resistance to PARP inhibitors: Genetic analysis of an ovarian cancer patient with germline BRCA1 variant who became resistant to PARP inhibitors2023
- Author(s)
  Hitomi Yamashita, Kentaro Nakayama, Hikaru Haraga, Tomoka Ishibashi, Masako Ishikawa, Koji Iida, Satoru Kyo
- Organizer
  第65回日本婦人科腫瘍学会学術講演会
- Data Source
  KAKENHI-PROJECT-22K16860
[Presentation] EP267 Identifying Carcinogenic Mechanism for Malignant Struma Ovarii Based on Genetic2022
- Author(s)
  Hitomi Yamashita, Kentaro Nakayama, Kousuke Kanno, Yuki Nonomura, Kiyoka Sawada, Ruriko Fukushima, Tomoka Ishibashi, Masako Ishikawa, Seiya Sato, Koji Iida, Satoru Kyo
- Organizer
  第64回日本婦人科腫瘍学会学術講演会
- Data Source
  KAKENHI-PROJECT-22K16860
[Presentation] ARID1A deficiency is not suitable as a biomarker for immune checkpoint inhibitors in endometrial cancer2022
- Author(s)
  Hitomi Yamashita, Kentaro Nakayama, Kousuke Kanno, Yuki Nonomura, Kiyoka Sawada, Ruriko Fukushima, Tomoka Ishibashi, Masako Ishikawa, Seiya Sato, Koji Iida, Satoru Kyo
- Organizer
  第74回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-22K16860

1. 中村康平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 中山健太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 石橋朋佳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 高倉正博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamashita Hitomi 山下 瞳

山下 瞳 ヤマシタ ヒトミ

Research Projects

Research Products

Co-Researchers

子宮体癌におけるPARP阻害薬とICI併用療法の有効性と分子基盤の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

婦人科希少がんオルガノイドライブラリーを基盤とした新規治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] The Case of an Endometrial Cancer Patient with Breast Cancer Who Has Achieved Long-Term Survival via Letrozole Monotherapy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Promising Therapeutic Impact of Immune Checkpoint Inhibitors in TypeⅡ Endometrial Cancer Patients with Deficient Mismatch Repair Status.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identifying the Carcinogenic Mechanism of Malignant Struma Ovarii Using Whole-Exome Sequencing and DNA Methylation Analysis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Histological and Genetic Diversity in Ovarian Mucinous Carcinomas:A Pilot Study.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ovarian Endometrioid and Clear Cell Carcinomas with Low Prevalence of Microsatellite Instability: A Unique Subset of Ovarian Carcinomas Could Benefit from Combination Therapy with Immune Checkpoint Inhibitors and Other Anticancer Agents2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mutation Profiles of Ovarian Seromucinous Borderline Tumors in Japanese Patients2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 特集 専攻医のうちにマスターしたい産婦人科の外来･短期滞在手術 総論 1.外陰･腟･子宮頸部の局所解剖2022

Author(s)

Journal Title

DOI

ISSN

Year and Date

Data Source

[Journal Article] Clinical Landscape of PARP Inhibitors in Ovarian Cancer: Molecular Mechanisms and Clues to Overcome Resistance2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Promising Therapeutic Impact of a Selective Estrogen Receptor Downregulator, Fulvestrant, as Demonstrated In Vitro upon Low-Grade Serous Ovarian Carcinoma Cell Lines2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Investigating the mechanism of resistance to PARP inhibitors: Genetic analysis of an ovarian cancer patient with germline BRCA1 variant who became resistant to PARP inhibitors2023

Author(s)

Organizer

Data Source

[Presentation] Investigating the mechanism of resistance to PARP inhibitors: Genetic analysis of an ovarian cancer patient with germline BRCA1 variant who became resistant to PARP inhibitors2023

Author(s)

Organizer

Data Source

[Presentation] EP267 Identifying Carcinogenic Mechanism for Malignant Struma Ovarii Based on Genetic2022

Author(s)

Organizer

Data Source

[Presentation] ARID1A deficiency is not suitable as a biomarker for immune checkpoint inhibitors in endometrial cancer2022

Author(s)

Organizer

Data Source

Yamashita Hitomi 山下瞳

山下瞳ヤマシタヒトミ

[Journal Article] 特集専攻医のうちにマスターしたい産婦人科の外来･短期滞在手術総論 1.外陰･腟･子宮頸部の局所解剖2022