Tokairin Kikutaro 東海林菊太郎

… Alternative Names

東海林菊太郎トウカイリンキクタロウ

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Researcher Number	70883164
Other IDs
Affiliation (Current)	2025: 北海道大学, 医学研究院, 客員研究員
Affiliation (based on the past Project Information) *help	2023 – 2024: 北海道大学, 医学研究院, 客員研究員 2023: 北海道大学, 大学病院, 医員 2020: 北海道大学, 大学病院, 医員
Review Section/Research Field	Principal Investigator 0803:Pathology, infection/immunology, and related fields Except Principal Investigator Basic Section 56010:Neurosurgery-related
Keywords	Principal Investigator 分化誘導 / 血管内皮細胞 / 血管平滑筋細胞 / 平滑筋細胞 / 内皮細胞 / iPS細胞 / もやもや病 Except Principal Investigator Moyamoya disease / microRNA / Epigenome … More / Pial synangiosis / 創始者変異 / RNF213 / エピゲノム / 血漿microRNA / 病態修飾因子 / 発症素因 / もやもや病 / pial synangiosis / angiogenesis / epigenome / blood biomarker / circulating microRNA Less

Epigenetic regulation analysis in angiogenesis/pial synangiosis on the meninges in Moyamoya disease
- Principal Investigator
  
  伊東雅基
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hokkaido University
Exploration of pathology in Moyamoya disease; co-culture model of vascular endothelial and smooth muscle cells derived from induced pluripotent stem cellsPrincipal Investigator
- Principal Investigator
  
  東海林菊太郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0803:Pathology, infection/immunology, and related fields
- Research Institution
  Hokkaido University
Comprehensive validation of circulating microRNA signatures for Moyamoya disease early detection as an epigenome blood biomarker
- Principal Investigator
  
  Ito Masaki
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hokkaido University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Predictive value of the hemispheric magnetic resonance angiography score on the development of indirect pial synangiosis after combined revascularization surgery for adult moyamoya disease2024
- Author(s)
  UCHINO Haruto, ITO Masaki, FUJIMA Noriyuki, TOKAIRIN Kikutaro, TATEZAWA Ryota, SUGIYAMA Taku, FUJIMURA Miki
- Journal Title
  
  Acta Neurochir (Wien)
  
  Volume: 166(1) Pages: 181-181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Association of RNF213 polymorphism and cortical hyperintensity sign on fluid-attenuated inversion recovery images after revascularization surgery for moyamoya disease: possible involvement of intrinsic vascular vulnerability2023
- Author(s)
  UCHINO Haruto、ITO Masaki、TOKAIRIN Kikutaro、TATEZAWA Ryota、SUGIYAMA Taku、KAZUMATA Ken、FUJIMURA Miki
- Journal Title
  
  Neurosurgical Review
  
  Volume: 46 Issue: 1 Pages: 119-119
- DOI
  10.1007/s10143-023-02030-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Impact of RNF213 c.14576G>A Variant on the Development of Direct and Indirect Revascularization in Pediatric Moyamoya Disease2022
- Author(s)
  Kawabori Masahito、Ito Masaki、Kazumata Ken、Tokairin Kikutaro、Hatanaka Kanako C.、Ishikawa Susumu、Houkin Kiyohiro、Fujimura Miki
- Journal Title
  
  Cerebrovascular Diseases
  
  Volume: 51 Issue: 2 Pages: 1-6
- DOI
  10.1159/000526089
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09362, KAKENHI-PROJECT-19H03765
[Journal Article] Impact of RNF213 founder polymorphism (p.R4810K) on the postoperative development of indirect pial synangiosis after direct/indirect combined revascularization surgery for adult Moyamoya disease2022
- Author(s)
  Ito Masaki、Kawabori Masahito、Sugiyama Taku、Tokairin Kikutaro、Tatezawa Ryota、Uchino Haruto、Kazumata Ken、Houkin Kiyohiro、Fujimura Miki
- Journal Title
  
  Neurosurgical Review
  
  Volume: online ahead of print Issue: 3 Pages: 2305-2313
- DOI
  10.1007/s10143-022-01749-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03765, KAKENHI-PROJECT-20K09362
[Journal Article] Intraoperative Early Venous Filling Phenomenon as an Intrinsic Sign of the Local Hemodynamic Change after Revascularization Surgery in a Patient with Adult Moyamoya Disease: Implications of a Potential Arteriovenous Shunt2021
- Author(s)
  TOKAIRIN Kikutaro、SUGIYAMA Taku、ITO Masaki、FUJIMURA Miki
- Journal Title
  
  NMC Case Report Journal
  
  Volume: 8 Issue: 1 Pages: 755-760
- DOI
  10.2176/nmccrj.cr.2021-0181
- NAID
  130008113035
- ISSN
  2188-4226
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03765, KAKENHI-PROJECT-20K09362
[Journal Article] Rescue extracranial-intracranial bypass for ischemic stroke secondary to progressive human immunodeficiency virus-associated vasculopathy2021
- Author(s)
  Mizushima M, Sugiyama T, Eguchi K, Tarisawa M, Tokairin K, Ito M, Hashimoto D, Yabe I, Fujimura M
- Journal Title
  
  J Neurol Surg A Cent Eur Neurosurgery
  
  Volume: online ahead of print Issue: 01 Pages: 088-093
- DOI
  10.1055/a-1779-4142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Association of cognitive function with cerebral blood flow in children with moyamoya disease2020
- Author(s)
  Kazumata Ken、Tokairin Kikutaro、Sugiyama Taku、Ito Masaki、Uchino Haruto、Osanai Toshiya、Kawabori Masahito、Nakayama Naoki、Houkin Kiyohiro
- Journal Title
  
  Journal of Neurosurgery: Pediatrics
  
  Volume: 25 Issue: 1 Pages: 62-68
- DOI
  10.3171/2019.7.peds19312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Immersive 3-Dimensional Virtual Reality Modeling for Case-Specific Presurgical Discussions in Cerebrovascular Neurosurgery2020
- Author(s)
  Sugiyama Taku、Clapp Tod、Nelson Jordan、Eitel Chad、Motegi Hiroaki、Nakayama Naoki、Sasaki Tsukasa、Tokairin Kikutaro、Ito Masaki、Kazumata Ken、Houkin Kiyohiro
- Journal Title
  
  Operative Neurosurgery
  
  Volume: 20 Issue: 3 Pages: 289-299
- DOI
  10.1093/ons/opaa335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Vascular Smooth Muscle Cell Derived from IPS Cell of Moyamoya Disease - Comparative Characterization with Endothelial Cell Transcriptome2020
- Author(s)
  Tokairin Kikutaro、Hamauchi Shuji、Ito Masaki、Kazumata Ken、Sugiyama Taku、Nakayama Naoki、Kawabori Masahito、Osanai Toshiya、Houkin Kiyohiro
- Journal Title
  
  Journal of Stroke and Cerebrovascular Diseases
  
  Volume: 29 Issue: 12 Pages: 105305-105305
- DOI
  10.1016/j.jstrokecerebrovasdis.2020.105305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03765
[Journal Article] Brain Structure, Connectivity, and Cognitive Changes Following Revascularization Surgery in Adult Moyamoya Disease2019
- Author(s)
  Kazumata Ken、Tha Khin Khin、Tokairin Kikutaro、Ito Masaki、Uchino Haruto、Kawabori Masahito、Sugiyama Taku
- Journal Title
  
  Neurosurgery
  
  Volume: 85 Issue: 5 Pages: E943-E952
- DOI
  10.1093/neuros/nyz176
- Data Source
  KAKENHI-PROJECT-19H03765
[Presentation] もやもや病のエピゲノム病態修飾因子＜血漿microRNA＞探索2024
- Author(s)
  伊東雅基、内野晴登、東海林菊太郎、杉山拓、川堀真人、岩田育子、矢部一郎、寳金清博、藤村幹
- Organizer
  第53回日本脳卒中の外科学会学術集会シンポジウム 02 (卒外SY02)
- Data Source
  KAKENHI-PROJECT-19H03765
[Presentation] RNF213創始者変異は成人もやもや病複合血行再建術後の間接バイパス路発達に寄与する2021
- Author(s)
  伊東雅基, 川堀真人, 杉山拓, 東海林菊太郎, 舘澤諒大, 内野晴登, 数又研, 寳金清博, 藤村幹
- Organizer
  第80回日本脳神経外科学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03765
[Presentation] 成人もやもや病に対する間接バイパス術に残された課題ーRNF213創始者変異術前検討の意義2021
- Author(s)
  伊東雅基, 川堀真人, 杉山拓, 東海林菊太郎, 舘澤諒大, 内野晴登, 数又研, 寳金清博, 藤村幹
- Organizer
  第51回　日本脳卒中の外科学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03765
[Presentation] 成人もやもや病複合血行再建術後バイパス路発達度におけるRNF213創始者変異の意義2021
- Author(s)
  伊東雅基、川堀真人、杉山拓、東海林菊太郎、舘澤諒大、内野晴登、数又研、寳金清博、藤村幹
- Organizer
  第39回 The Mt. Fuji workshop on CVD
- Data Source
  KAKENHI-PROJECT-19H03765
[Presentation] RNF213創始者変異は成人もやもや病複合血行再建術後の間接バイパス路発達に寄与する2021
- Author(s)
  伊東雅基, 川堀真人, 杉山拓, 東海林菊太郎, 舘澤諒大, 内野晴登, 数又研, 寳金清博, 藤村幹
- Organizer
  第64回　日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03765

1. Ito Masaki (10399850)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
2. 藤村幹 (00361098)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. 内野晴登 (40775144)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
4. 佐藤典宏 (50360912)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 矢部一郎 (60372273)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 杉山拓 (70748863)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
7. 寳金清博 (90229146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
8. 中山若樹 (40421961)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. 数又研 (60634144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
10. 浜内祝嗣 (70794387)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Tokairin Kikutaro 東海林 菊太郎

東海林 菊太郎 トウカイリン キクタロウ

Research Projects

Research Products

Co-Researchers

Epigenetic regulation analysis in angiogenesis/pial synangiosis on the meninges in Moyamoya disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploration of pathology in Moyamoya disease; co-culture model of vascular endothelial and smooth muscle cells derived from induced pluripotent stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive validation of circulating microRNA signatures for Moyamoya disease early detection as an epigenome blood biomarker

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Predictive value of the hemispheric magnetic resonance angiography score on the development of indirect pial synangiosis after combined revascularization surgery for adult moyamoya disease2024

Author(s)

Journal Title

Data Source

[Journal Article] Association of RNF213 polymorphism and cortical hyperintensity sign on fluid-attenuated inversion recovery images after revascularization surgery for moyamoya disease: possible involvement of intrinsic vascular vulnerability2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of RNF213 c.14576G>A Variant on the Development of Direct and Indirect Revascularization in Pediatric Moyamoya Disease2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of RNF213 founder polymorphism (p.R4810K) on the postoperative development of indirect pial synangiosis after direct/indirect combined revascularization surgery for adult Moyamoya disease2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intraoperative Early Venous Filling Phenomenon as an Intrinsic Sign of the Local Hemodynamic Change after Revascularization Surgery in a Patient with Adult Moyamoya Disease: Implications of a Potential Arteriovenous Shunt2021

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Rescue extracranial-intracranial bypass for ischemic stroke secondary to progressive human immunodeficiency virus-associated vasculopathy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association of cognitive function with cerebral blood flow in children with moyamoya disease2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immersive 3-Dimensional Virtual Reality Modeling for Case-Specific Presurgical Discussions in Cerebrovascular Neurosurgery2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vascular Smooth Muscle Cell Derived from IPS Cell of Moyamoya Disease - Comparative Characterization with Endothelial Cell Transcriptome2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Brain Structure, Connectivity, and Cognitive Changes Following Revascularization Surgery in Adult Moyamoya Disease2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] もやもや病のエピゲノム病態修飾因子＜血漿microRNA＞探索2024

Author(s)

Organizer

Data Source

[Presentation] RNF213創始者変異は成人もやもや病複合血行再建術後の間接バイパス路発達に寄与する2021

Tokairin Kikutaro 東海林菊太郎

東海林菊太郎トウカイリンキクタロウ