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Himeoka Yusuke  姫岡 優介

ORCIDConnect your ORCID iD *help
Researcher Number 70903160
Other IDs
Affiliation (Current) 2025: 東京大学, 大学院理学系研究科(理学部), 助教
Affiliation (based on the past Project Information) *help 2021 – 2025: 東京大学, 大学院理学系研究科(理学部), 助教
Review Section/Research Field
Principal Investigator
Transformative Research Areas, Section (II) / Basic Section 43040:Biophysics-related / 0701:Biology at molecular to cellular levels, and related fields
Keywords
Principal Investigator
ネットワーク / 力学系 / 数理モデル / 化学反応 / 微分方程式 / 休眠状態 / ダイナミクス / 代謝モデル / 代謝 / システム生物学 … More / デザイン / 分子システム / 適応度地形 / 化学反応ネットワーク / 人工反応系 / 無細胞翻訳系 / シミュレーション / 化学反応動力学 / PUREシステム / 反応動力学 / 動力学モデル / 細胞 / 動力学 / 休眠 / 微生物 Less
  • Research Projects

    (7 results)
  • Research Products

    (44 results)
  •  A unified science of "life/non-life transition" encompassing cells and artificial cellsArea Organizer

    • Area Organizer
      姫岡 優介
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
  •  『生命-非生命転移』学の創出Principal Investigator

    • Principal Investigator
      姫岡 優介
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (II)
    • Research Institution
      The University of Tokyo
  •  大腸菌における『生命-非生命転移境界』の可逆的横断Principal Investigator

    • Principal Investigator
      姫岡 優介
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (II)
    • Research Institution
      The University of Tokyo
  •  数理モデルを用いた分子システム適応度地形のデザイン原理の解明Principal Investigator

    • Principal Investigator
      姫岡 優介
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (II)
    • Research Institution
      The University of Tokyo
  •  人工的代謝ネットワークを用いた静止相における細胞代謝ダイナミクスの研究Principal Investigator

    • Principal Investigator
      姫岡 優介
    • Project Period (FY)
      2022 – 2026
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      The University of Tokyo
  •  化学反応動力学理論を用いた頑健な反応経路設計アルゴリズムの開発Principal Investigator

    • Principal Investigator
      姫岡 優介
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (II)
    • Research Institution
      The University of Tokyo
  •  Exploring roles of the metabolic network structure in bacterial dormancyPrincipal Investigator

    • Principal Investigator
      Himeoka Yusuke
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0701:Biology at molecular to cellular levels, and related fields
    • Research Institution
      The University of Tokyo

All 2024 2023 2022

All Journal Article Presentation Book

  • [Book] システム生物学入門2023

    • Author(s)
      畠山 哲央、姫岡 優介
    • Total Pages
      288
    • Publisher
      講談社
    • ISBN
      9784065334348
    • Data Source
      KAKENHI-PROJECT-22K15069
  • [Journal Article] Perturbation-response analysis of<i>in silico</i>metabolic dynamics in nonlinear regime: Hard-coded responsiveness in the cofactors and network sparsity2024

    • Author(s)
      Himeoka Yusuke、Furusawa Chikara
    • Journal Title

      eLife (to be appeared)

      Volume: -

    • DOI

      10.1101/2023.10.18.562862

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K15069, KAKENHI-PROJECT-22K21344, KAKENHI-PUBLICLY-22H05403
  • [Journal Article] Evolution of hierarchy and irreversibility in theoretical cell differentiation model2023

    • Author(s)
      Nakamura Yoshiyuki T、Himeoka Yusuke、Saito Nen、Furusawa Chikara
    • Journal Title

      PNAS Nexus

      Volume: 3 Issue: 1 Pages: 454-454

    • DOI

      10.1093/pnasnexus/pgad454

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K15069, KAKENHI-PROJECT-22K21344, KAKENHI-PUBLICLY-22H05403
  • [Journal Article] Emergence of growth and dormancy from a kinetic model of the <i>Escherichia coli</i> central carbon metabolism2022

    • Author(s)
      Himeoka Yusuke、Mitarai Namiko
    • Journal Title

      Physical Review Research

      Volume: 4 Issue: 4 Pages: 043223-043223

    • DOI

      10.1103/physrevresearch.4.043223

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20626
  • [Journal Article] Structural determinants of relaxation dynamics in chemical reaction networks2022

    • Author(s)
      Himeoka Yusuke、Kirkegaard Julius B.、Mitarai Namiko、Krishna Sandeep
    • Journal Title

      bioRxiv

      Volume: -

    • DOI

      10.1101/2022.05.25.493374

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15069, KAKENHI-PUBLICLY-22H05403
  • [Presentation] 大腸菌代謝動力学モデルの恒常性と死2024

    • Author(s)
      姫岡優介
    • Organizer
      第11回定量生物学の会年会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] Terraced NK modelにおける遺伝子型の自由度と進化速度の関係2024

    • Author(s)
      池田雄太郎, 姫岡優介, 古澤力
    • Organizer
      第11回定量生物学の会年会
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] 細菌の休眠状態と代謝ダイナミクスの安定性2024

    • Author(s)
      姫岡優介
    • Organizer
      多細胞休止を研究する会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] Solving differential equations for chemical kinetics using quantics tensor train2024

    • Author(s)
      Rihito Sakurai, Wataru Mizukami, Yuta Mizuno, Yusuke Himeoka, Hiroshi Shinaoka
    • Organizer
      APS March Meeting 2024
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] Updating parameters of in silico PURE system model ePURE ) based on experimental observations2024

    • Author(s)
      Shunnosuke Ban, Yusuke Himeoka, Tomoaki Matsuura, Yoshihiro Shimizu, Chikara Furusawa
    • Organizer
      Korea-Japan Joint Workshop of Bottom-up Synthetic Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15069
  • [Presentation] Solving differential equations for chemical kinetics using quantics tensor train2024

    • Author(s)
      Rihito Sakurai, Wataru Mizukami, Yuta Mizuno, Yusuke Himeoka, Hiroshi Shinaoka
    • Organizer
      APS March Meeting 2024
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15069
  • [Presentation] in silico細胞死2024

    • Author(s)
      姫岡優介
    • Organizer
      非平衡系の物理
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] Updating parameters of in silico PURE system model ePURE ) based on experimental observations2024

    • Author(s)
      Shunnosuke Ban, Yusuke Himeoka, Tomoaki Matsuura, Yoshihiro Shimizu, Chikara Furusawa
    • Organizer
      Korea-Japan Joint Workshop of Bottom-up Synthetic Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] Emergence of Complex Host-Parasite networks of replicating RNA molecules: A Computational Analysis2023

    • Author(s)
      Kei Nishida, Yusuke Himeoka, Chikara Furusawa
    • Organizer
      Statphys28 Satellite meeting Statistical Physics and Information-Processing in Living Systems
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15069
  • [Presentation] Disruption of homeostasis and death in kinetic models of Escherichia coli metabolism2023

    • Author(s)
      Yusuke HImeoka, Chikara Furusawa
    • Organizer
      Statphys28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15069
  • [Presentation] Solving differential equations for chemical kinetics using quantics tensor train2023

    • Author(s)
      Rihito Sakurai, Wataru Mizukami, Yuta Mizuno, Yusuke Himeoka, Hiroshi Shinaoka
    • Organizer
      Computational Approaches to Quantum Many-Body Systems
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15069
  • [Presentation] 代謝ネットワークの構造と摂動への応答性の関係2023

    • Author(s)
      姫岡優介, 古澤力
    • Organizer
      「細胞を創る」研究会16.0
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] Simulating fast and slow chemical kinetics with dynamic mode decomposition2023

    • Author(s)
      Yuta Mizuno, Yosuke Sumiya, Yusuke Himeoka
    • Organizer
      38th Symposium on Chemical Kinetics and Dynamics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] Solving differential equations for chemical kinetics using quantics tensor train2023

    • Author(s)
      Rihito Sakurai, Wataru Mizukami, Yuta Mizuno, Yusuke Himeoka, Hiroshi Shinaoka
    • Organizer
      Computational Approaches to Quantum Many-Body Systems
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] Disruption of metabolic homeostasis: Responsiveness due to the cofactor dynamics and network sparsity2023

    • Author(s)
      姫岡優介, 古澤力
    • Organizer
      日本生物物理学会第61回年会
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] Disruption of metabolic homeostasis: Sensitivity due to the network structure2023

    • Author(s)
      Yusuke HImeoka, Chikara Furusawa
    • Organizer
      Statphys28 Satellite meeting Statistical Physics and Information-Processing in Living Systems
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15069
  • [Presentation] Exploring Host-Parasite Networks of Replicating RNA through Computational Simulations2023

    • Author(s)
      西田慧,姫岡優介,古澤力
    • Organizer
      日本進化学会第25回大会
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] Disruption of metabolic homeostasis: Sensitivity due to the network structure2023

    • Author(s)
      Yusuke HImeoka, Chikara Furusawa
    • Organizer
      Statphys28 Satellite meeting Statistical Physics and Information-Processing in Living Systems
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] Emergence of Complex Host-Parasite networks of replicating RNA molecules: A Computational Analysis2023

    • Author(s)
      Kei Nishida, Yusuke Himeoka, Chikara Furusawa
    • Organizer
      Statphys28 Satellite meeting Statistical Physics and Information-Processing in Living Systems
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] 代謝反応ダイナミクスの摂動応答関係とネットワーク構造2023

    • Author(s)
      姫岡優介, 古澤力
    • Organizer
      研究会「理論と実験」
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] Disruption of homeostasis and death in kinetic models of Escherichia coli metabolism2023

    • Author(s)
      Yusuke HImeoka, Chikara Furusawa
    • Organizer
      Statphys28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] Solving differential equations for chemical kinetics using quantics tensor train2023

    • Author(s)
      Rihito Sakurai, Wataru Mizukami, Yuta Mizuno, Yusuke Himeoka, Hiroshi Shinaoka
    • Organizer
      Trends in the Theory of Quantum Materials 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] Solving differential equations for chemical kinetics using quantics tensor train2023

    • Author(s)
      Rihito Sakurai, Wataru Mizukami, Yuta Mizuno, Yusuke Himeoka, Hiroshi Shinaoka
    • Organizer
      Trends in the Theory of Quantum Materials 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15069
  • [Presentation] Perturbation-response analysis of in silico metabolic dynamics: Hard-coded responsiveness in the cofactor and network sparsity2023

    • Author(s)
      Yusuke Himeoka
    • Organizer
      Asia Synthetic Biology Association meeting 2023
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] ネットワークの構造と代謝状態の恒常性2023

    • Author(s)
      姫岡優介
    • Organizer
      日本生物物理学会サブグループ 人工細胞モデル&分子ロボティクス 第4回研究会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] Perturbation-response analysis of in silico metabolic dynamics: Hard-coded responsiveness in the cofactor and network sparsity2023

    • Author(s)
      Yusuke Himeoka
    • Organizer
      Asia Synthetic Biology Association meeting 2023
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15069
  • [Presentation] 代謝ホメオスタシスの擾乱とネットワークの構造の関係2023

    • Author(s)
      姫岡優介, 古澤力
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] Structure of catalytic reaction network for specialized compartments evolution2023

    • Author(s)
      Shunsuke Ichii, Yusuke Himeoka, Chikara Furusawa
    • Organizer
      STATPHYS28 Satellite Meeting 窶彜tatistical Physics and Information-Processing in Living Systems窶?
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15069
  • [Presentation] Simulating fast and slow chemical kinetics with dynamic mode decomposition2023

    • Author(s)
      Yuta Mizuno, Yosuke Sumiya, Yusuke Himeoka
    • Organizer
      38th Symposium on Chemical Kinetics and Dynamics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15069
  • [Presentation] Structure of catalytic reaction network for specialized compartments evolution2023

    • Author(s)
      Shunsuke Ichii, Yusuke Himeoka, Chikara Furusawa
    • Organizer
      STATPHYS28 Satellite Meeting Statistical Physics and Information-Processing in Living Systems窶?
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-22H05403
  • [Presentation] Emergence of growth and dormancy from a kinetic model of the Escherichia coli central carbon metabolism2022

    • Author(s)
      Yusuke Himeoka
    • Organizer
      Roles of Heterogeneity in Nonequilibrium Collective Dynamics 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20626
  • [Presentation] 大腸菌中心代謝ネットワークから生じる休眠状態様のダイナミクス2022

    • Author(s)
      姫岡優介
    • Organizer
      理論合成インシリコ生物学セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K20626
  • [Presentation] 大腸菌代謝モデルを用いた休眠状態への遷移ダイナミクスの研究2022

    • Author(s)
      姫岡優介
    • Organizer
      第2回深津ERATOプロジェクト全体会議
    • Data Source
      KAKENHI-PROJECT-21K20626
  • [Presentation] Emergence of growth and dormancy from a kinetic model of the Escherichia coli central carbon metabolism2022

    • Author(s)
      Yusuke Himeoka
    • Organizer
      RIKEN iTHEMS Seminar
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K20626
  • [Presentation] 人工的な代謝ネットワークの緩和特性とネットワーク構造2022

    • Author(s)
      姫岡優介
    • Organizer
      日本物理学会
    • Data Source
      KAKENHI-PROJECT-21K20626
  • [Presentation] Disruption of metabolic homeostasis : Sensitivity due to the network structure2022

    • Author(s)
      Yusuke Himeoka
    • Organizer
      Quantitative Biology of Non-growing Microbes,
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20626
  • [Presentation] 人工的な代謝ネットワークの緩和特性とネットワーク構造2022

    • Author(s)
      姫岡優介
    • Organizer
      日本物理学会第 77 回年次大会
    • Data Source
      KAKENHI-PROJECT-22K15069
  • [Presentation] Emergence of growth and dormancy from a kinetic model of the Escherichia coli central carbon metabolism2022

    • Author(s)
      Yusuke HImeoka
    • Organizer
      , Major ideas in quantitative microbial physiology: Past, Present and Future,
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20626
  • [Presentation] 細胞の休眠ダイナミクスと代謝ネットワーク構造2022

    • Author(s)
      姫岡優介
    • Organizer
      ネットワーク科学研究会2022
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K20626

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