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Kobayashi Mako  小林 真子

ORCIDConnect your ORCID iD *help
Researcher Number 70908912
Other IDs
Affiliation (Current) 2025: 東北大学, 工学研究科, 助教
Affiliation (based on the past Project Information) *help 2022 – 2024: 東北大学, 工学研究科, 助教
2021: 東京医科歯科大学, 生体材料工学研究所, 特任研究員
Review Section/Research Field
Principal Investigator
Basic Section 90120:Biomaterials-related / 0403:Biomedical engineering and related fields
Except Principal Investigator
Medium-sized Section 90:Biomedical engineering and related fields
Keywords
Principal Investigator
3Dバイオプリンティング / 脱細胞化組織 / がん / 細胞外マトリクス / 細胞担持微粒子 / 脱細胞化生体組織 / サポートバス
Except Principal Investigator
骨ナノ組織工学 / 中空チタンナノファイバー / 骨オルガノイド … More / 細胞外小胞体 / 埋込型医療デバイス / マトリックス結合型ベシクル / 細胞外マトリックス / 免疫反応 / 細胞外小胞 / 再生医療 / 脱細胞化組織 / 組織工学 Less
  • Research Projects

    (4 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (8 People)
  •  Challenges to develop bone-nano tissue engineering using metallic hollow tubes

    • Principal Investigator
      山本 雅哉
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Tohoku University
  •  細胞外マトリクスの特性が3Dがん微小環境構築に与える影響の解明Principal Investigator

    • Principal Investigator
      小林 真子
    • Project Period (FY)
      2023 – 2027
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 90120:Biomaterials-related
    • Research Institution
      Tohoku University
  •  Elucidating the effects of the spatial location and density of cancer cells within the extracellular matrix on cell behavior and function.Principal Investigator

    • Principal Investigator
      Kobayashi Mako
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0403:Biomedical engineering and related fields
    • Research Institution
      Tohoku University
      Tokyo Medical and Dental University
  •  Investigation of Decellularized Tissue Functions to Obtain Guidelines for Designing Destination Use Devices

    • Principal Investigator
      岸田 晶夫
    • Project Period (FY)
      2021 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Tokyo Medical and Dental University

All 2024 2023 2022 2021

All Journal Article Presentation

  • [Journal Article] In Vitro Tissue Reconstruction Using Decellularized Pericardium Cultured with Cells for Ligament Regeneration2022

    • Author(s)
      Suzuki Mika、Kimura Tsuyoshi、Yoshida Yukina、Kobayashi Mako、Hashimoto Yoshihide、Takahashi Hironobu、Shimizu Tatsuya、Anzai Shota、Nakamura Naoko、Kishida Akio
    • Journal Title

      Polymers

      Volume: 14 Issue: 12 Pages: 2351-2351

    • DOI

      10.3390/polym14122351

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H04954
  • [Journal Article] A novel approach for the endothelialization of xenogeneic decellularized vascular tissues by human cells utilizing surface modification and dynamic culture2022

    • Author(s)
      Ho Wen-Jin、Kobayashi Mako、Murata Kozue、Hashimoto Yoshihide、Izumi Kenji、Kimura Tsuyoshi、Kanemitsu Hideo、Yamazaki Kazuhiro、Ikeda Tadashi、Minatoya Kenji、Kishida Akio、Masumoto Hidetoshi
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 22294-22294

    • DOI

      10.1038/s41598-022-26792-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08918, KAKENHI-PROJECT-22K08934, KAKENHI-PROJECT-22K08956, KAKENHI-PROJECT-21H04954, KAKENHI-PROJECT-20H03764, KAKENHI-PROJECT-20K09125, KAKENHI-PROJECT-23K24420
  • [Journal Article] Extraction and Biological Evaluation of Matrix-Bound Nanovesicles (MBVs) from High-Hydrostatic Pressure-Decellularized Tissues2022

    • Author(s)
      Kobayashi Mako、Ishida Naoki、Hashimoto Yoshihide、Negishi Jun、Saga Hideki、Sasaki Yoshihiro、Akiyoshi Kazunari、Kimura Tsuyoshi、Kishida Akio
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 16 Pages: 8868-8868

    • DOI

      10.3390/ijms23168868

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H04954
  • [Journal Article] Preparation of mineralized pericardium by alternative soaking for soft?hard interregional tissue application2022

    • Author(s)
      Suzuki Mika、Kimura Tsuyoshi、Nakano Yuta、Kobayashi Mako、Okada Masahiro、Matsumoto Takuya、Nakamura Naoko、Hashimoto Yoshihide、Kishida Akio
    • Journal Title

      Journal of Biomedical Materials Research Part A

      Volume: 111 Issue: 2 Pages: 198-208

    • DOI

      10.1002/jbm.a.37445

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H04954, KAKENHI-PROJECT-21H03123
  • [Presentation] Preparation of bioink containing decellularized tissue powder for 3D cancer microenvironment.2024

    • Author(s)
      Mako Kobayashi
    • Organizer
      Global Young Scientist Summit (GYSS)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K17207
  • [Presentation] マクロファージ分極を指標と した種々の脱細胞化組織の生体受容性評価.2024

    • Author(s)
      木村剛, 萩原萌子, 石垣瑠梨, 橋本良秀, 小林真子, 野村 渉, 山本雅哉, 岸田晶夫.
    • Organizer
      第22回日 本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-21H04954
  • [Presentation] 3D-cultured cancer spheroid behavior within decellularized extracellular matrix (dECM) powder based bioink.2023

    • Author(s)
      Mako Kobayashi
    • Organizer
      TERMIS-AP
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K17207
  • [Presentation] Freeform Reversible Embedding of Suspended Hydrogel (FRESH) 3D bioprinting using Decellularized Extracellular Matrix (dECM) powder based bio-ink.2023

    • Author(s)
      Lucas COLLET, Mako Kobayashi, Masaya Yamamoto
    • Organizer
      TOHOKU University 2022-2023 FALL Semester JYPE & COLABS
    • Data Source
      KAKENHI-PROJECT-21K20512
  • [Presentation] 脱細胞化脳・胎盤由来 マトリクス結合型ナノベシクル(MBV)の 抽出と神経機能修復への効果検討2023

    • Author(s)
      小林真子, 石田直樹, 橋本良秀, 根岸淳, 佐々木善浩, 秋吉一成, 山本雅哉, 木村剛, 岸田晶夫
    • Organizer
      第35回代用臓器・再生医学研究会総会 日本バイオマテリアル学会北海道ブロック第7回研究会
    • Data Source
      KAKENHI-PROJECT-21K20512
  • [Presentation] Factors contributing to the functionality of decellularized tissues.2023

    • Author(s)
      Mako Kobayashi
    • Organizer
      JSPS-NRF Bilateral Program Mini-Symposium on Advanced Biomaterials for Tissue Engineering, and Tissue Synthesis and Manipulation
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20512
  • [Presentation] 3D細胞外マトリクス中のがんスフェロイド挙動評価2023

    • Author(s)
      小林真子
    • Organizer
      日本金属学会2023年秋季大会
    • Data Source
      KAKENHI-PROJECT-23K17207
  • [Presentation] 細胞外マトリクス環境に着目したがん微小環境構築の検討2023

    • Author(s)
      小林真子
    • Organizer
      2023年度東北大学金属材料研究所共同研究ワークショップ 日本バイオマテリアル学会東北ブロック交流会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K17207
  • [Presentation] A novel approach for pre-implant endothelialization of xenogeneic decellularized vascular tissues by human endothelial cells utilizing tissue surface modification and dynamic culture2022

    • Author(s)
      Wen-Jin Ho, Hidetoshi Masumoto, Mako Kobayashi, Kozue Murata, Tadashi Ikeda, Yoshihide Hashimoto, Tsuyoshi Kimura, Kenji Minatoya, Akio Kishida
    • Organizer
      American Heart Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H04954
  • [Presentation] 種々の脱細胞化組織由来マトリクス結合型ナノベシクルの評価2022

    • Author(s)
      小林真子, 橋本良秀, 根岸淳, 嵯峨秀樹, 佐々木善浩, 秋吉一成, 木村剛, 岸田晶夫
    • Organizer
      令和3年度生体医歯工学共同研究拠点成果報告会
    • Data Source
      KAKENHI-PROJECT-21K20512
  • [Presentation] The effect of decellularized tissue-derived hydrogels on cancer cell behavior.2022

    • Author(s)
      Mako Kobayashi, Tsuyoshi Kimura, Akio Kishida, Masaya Yamamoto
    • Organizer
      The 7th International Symposium on Biomedical Engineering (ISBE2022)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20512
  • [Presentation] The effects of matrix-bound nanovesicles (MBVs) derived from high-hydrostatic pressure decellularized tissues on neural regeneration2022

    • Author(s)
      Mako Kobayashi, Naoki Ishida, Yoshihide Hashimoto, Jun Negishi, Hideki Saga, Takehiro Iwanaga, Yoshihiro Sasaki, Kazunari Akiyoshi, Tsuyoshi Kimura, Akio Kishida.
    • Organizer
      TERMIS-AP
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H04954
  • [Presentation] 種々の脱細胞化組織由来マトリクス結合型ナノベシクル(MBV)の神経再生への効果2022

    • Author(s)
      小林真子, 石田直樹, 橋本良秀, 根岸淳, 嵯峨秀樹, 佐々木善浩, 秋吉一成, 山本雅哉, 木村剛, 岸田晶夫
    • Organizer
      第12回DDS再生医療研究会・第14回多血小板血漿(PRP)療法研究会
    • Data Source
      KAKENHI-PROJECT-21K20512
  • [Presentation] The effects of matrix-bound nanovesicles (MBVs) derived from high-hydrostatic pressure decellularized tissues on neural regeneration.2022

    • Author(s)
      Mako Kobayashi, Naoki Ishida, Yoshihide Hashimoto, Jun Negish, Hideki Saga, Takehiro Iwanaga, Yoshihiro Sasaki, Kazunari Akiyoshi, Tsuyoshi Kimura, Akio Kishida
    • Organizer
      TERMIS AP 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20512
  • [Presentation] 脱細胞化角膜実質足場における角膜上皮・内皮細胞の挙動.2022

    • Author(s)
      橋本良秀, 大橋慶子, 萩原萌子, 木村剛,小林尚俊,岸田晶夫.
    • Organizer
      第44回日本バイオマテリアル学会大会
    • Data Source
      KAKENHI-PROJECT-21H04954
  • [Presentation] 高静水圧法により作製した脱細胞化組織由来マトリクス結合型ナノベシクル(MBVs)の神経再生への機能評価2022

    • Author(s)
      小林真子, 石田直樹, 橋本良秀, 根岸淳, 嵯峨秀樹, 佐々木善浩, 秋吉一成, 木村剛, 岸田晶夫.
    • Organizer
      第9回日本細胞外小胞学会学術集会
    • Data Source
      KAKENHI-PROJECT-21H04954
  • [Presentation] 高静水圧法により作製した脱細胞化組織由来マトリクス結合型ナノベシクル(MBVs)の神経再生への機能評価2022

    • Author(s)
      小林真子, 石田直樹, 橋本良秀, 根岸淳, 嵯峨秀樹, 佐々木善浩, 秋吉一成, 木村剛, 岸田晶夫
    • Organizer
      第9回日本細胞外小胞学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K20512
  • [Presentation] The evaluation of matrix-bound nanovesicles (MBVs) derived from various high-hydrostatic pressure decellularized tissues2021

    • Author(s)
      Mako Kobayashi, Yoshihide Hashimoto, Jun Negishi, Hideki Saga, Yoshihiro Sasaki, Kazunari Akiyoshi, Tsuyoshi Kimura, Akio Kishida
    • Organizer
      第43回日本バイオマテリアル学会大会 第8回アジアバイオマテリアル学会 併催
    • Data Source
      KAKENHI-PROJECT-21K20512
  • [Presentation] Extraction of matrix-bound nanovesicles (MBVs) from high-hydrostatic pressure decellularized tissue and evaluation on vascular endothelial cells2021

    • Author(s)
      Mako Kobayashi, Naoki Ishida, Yoshihide Hashimoto, Jun Negishi, Hideki Saga, Yoshihiro Sasaki, Kazunari Akiyoshi, Tsuyoshi Kimura, Akio Kishida
    • Organizer
      TERMIS-2021(Tissue Engineering and Regenerative Medicine International Society-World Congress2021)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20512
  • [Presentation] 高静水圧法により作製した種々の脱細胞化組織由来マトリクス結合型ナノベシクルの評価2021

    • Author(s)
      小林真子, 石田直樹, 橋本良秀, 根岸淳, 嵯峨秀樹, 佐々木善浩, 秋吉一成, 木村剛, 岸田晶夫
    • Organizer
      第8回日本細胞外小胞学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K20512
  • 1.  岸田 晶夫 (60224929)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 2.  木村 剛 (10393216)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 3.  橋本 良秀 (40638384)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 4.  中村 奈緒子 (70754878)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  佐々木 善浩 (90314541)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  山本 雅哉 (10332735)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  池田 義
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  升本 英利
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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