Kobayashi Mako 小林真子

Researcher Number	70908912
Other IDs
Affiliation (Current)	2025: 東北大学, 工学研究科, 助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 東北大学, 工学研究科, 助教 2021: 東京医科歯科大学, 生体材料工学研究所, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 90120:Biomaterials-related / 0403:Biomedical engineering and related fields Except Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields
Keywords	Principal Investigator 3Dバイオプリンティング / 脱細胞化組織 / がん / 細胞外マトリクス / 細胞担持微粒子 / 脱細胞化生体組織 / サポートバス Except Principal Investigator 骨ナノ組織工学 / 中空チタンナノファイバー / 骨オルガノイド … More / 細胞外小胞体 / 埋込型医療デバイス / マトリックス結合型ベシクル / 細胞外マトリックス / 免疫反応 / 細胞外小胞 / 再生医療 / 脱細胞化組織 / 組織工学 Less

Challenges to develop bone-nano tissue engineering using metallic hollow tubes
- Principal Investigator
  
  山本雅哉
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Tohoku University
細胞外マトリクスの特性が3Dがん微小環境構築に与える影響の解明Principal Investigator
- Principal Investigator
  
  小林真子
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Tohoku University
Elucidating the effects of the spatial location and density of cancer cells within the extracellular matrix on cell behavior and function.Principal Investigator
- Principal Investigator
  
  Kobayashi Mako
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0403:Biomedical engineering and related fields
- Research Institution
  Tohoku University
  Tokyo Medical and Dental University
Investigation of Decellularized Tissue Functions to Obtain Guidelines for Designing Destination Use Devices
- Principal Investigator
  
  岸田晶夫
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Tokyo Medical and Dental University

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] In Vitro Tissue Reconstruction Using Decellularized Pericardium Cultured with Cells for Ligament Regeneration2022
- Author(s)
  Suzuki Mika、Kimura Tsuyoshi、Yoshida Yukina、Kobayashi Mako、Hashimoto Yoshihide、Takahashi Hironobu、Shimizu Tatsuya、Anzai Shota、Nakamura Naoko、Kishida Akio
- Journal Title
  
  Polymers
  
  Volume: 14 Issue: 12 Pages: 2351-2351
- DOI
  10.3390/polym14122351
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04954
[Journal Article] A novel approach for the endothelialization of xenogeneic decellularized vascular tissues by human cells utilizing surface modification and dynamic culture2022
- Author(s)
  Ho Wen-Jin、Kobayashi Mako、Murata Kozue、Hashimoto Yoshihide、Izumi Kenji、Kimura Tsuyoshi、Kanemitsu Hideo、Yamazaki Kazuhiro、Ikeda Tadashi、Minatoya Kenji、Kishida Akio、Masumoto Hidetoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 22294-22294
- DOI
  10.1038/s41598-022-26792-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08918, KAKENHI-PROJECT-22K08934, KAKENHI-PROJECT-22K08956, KAKENHI-PROJECT-21H04954, KAKENHI-PROJECT-20H03764, KAKENHI-PROJECT-20K09125, KAKENHI-PROJECT-23K24420
[Journal Article] Extraction and Biological Evaluation of Matrix-Bound Nanovesicles (MBVs) from High-Hydrostatic Pressure-Decellularized Tissues2022
- Author(s)
  Kobayashi Mako、Ishida Naoki、Hashimoto Yoshihide、Negishi Jun、Saga Hideki、Sasaki Yoshihiro、Akiyoshi Kazunari、Kimura Tsuyoshi、Kishida Akio
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 16 Pages: 8868-8868
- DOI
  10.3390/ijms23168868
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04954
[Journal Article] Preparation of mineralized pericardium by alternative soaking for soft?hard interregional tissue application2022
- Author(s)
  Suzuki Mika、Kimura Tsuyoshi、Nakano Yuta、Kobayashi Mako、Okada Masahiro、Matsumoto Takuya、Nakamura Naoko、Hashimoto Yoshihide、Kishida Akio
- Journal Title
  
  Journal of Biomedical Materials Research Part A
  
  Volume: 111 Issue: 2 Pages: 198-208
- DOI
  10.1002/jbm.a.37445
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04954, KAKENHI-PROJECT-21H03123
[Presentation] Preparation of bioink containing decellularized tissue powder for 3D cancer microenvironment.2024
- Author(s)
  Mako Kobayashi
- Organizer
  Global Young Scientist Summit (GYSS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17207
[Presentation] マクロファージ分極を指標とした種々の脱細胞化組織の生体受容性評価.2024
- Author(s)
  木村剛, 萩原萌子, 石垣瑠梨, 橋本良秀, 小林真子, 野村渉, 山本雅哉, 岸田晶夫.
- Organizer
  第22回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-21H04954
[Presentation] 3D-cultured cancer spheroid behavior within decellularized extracellular matrix (dECM) powder based bioink.2023
- Author(s)
  Mako Kobayashi
- Organizer
  TERMIS-AP
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17207
[Presentation] Freeform Reversible Embedding of Suspended Hydrogel (FRESH) 3D bioprinting using Decellularized Extracellular Matrix (dECM) powder based bio-ink.2023
- Author(s)
  Lucas COLLET, Mako Kobayashi, Masaya Yamamoto
- Organizer
  TOHOKU University 2022-2023 FALL Semester JYPE & COLABS
- Data Source
  KAKENHI-PROJECT-21K20512
[Presentation] 脱細胞化脳・胎盤由来マトリクス結合型ナノベシクル（MBV）の抽出と神経機能修復への効果検討2023
- Author(s)
  小林真子, 石田直樹, 橋本良秀, 根岸淳, 佐々木善浩, 秋吉一成, 山本雅哉, 木村剛, 岸田晶夫
- Organizer
  第35回代用臓器・再生医学研究会総会日本バイオマテリアル学会北海道ブロック第7回研究会
- Data Source
  KAKENHI-PROJECT-21K20512
[Presentation] Factors contributing to the functionality of decellularized tissues.2023
- Author(s)
  Mako Kobayashi
- Organizer
  JSPS-NRF Bilateral Program Mini-Symposium on Advanced Biomaterials for Tissue Engineering, and Tissue Synthesis and Manipulation
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20512
[Presentation] 3D細胞外マトリクス中のがんスフェロイド挙動評価2023
- Author(s)
  小林真子
- Organizer
  日本金属学会2023年秋季大会
- Data Source
  KAKENHI-PROJECT-23K17207
[Presentation] 細胞外マトリクス環境に着目したがん微小環境構築の検討2023
- Author(s)
  小林真子
- Organizer
  2023年度東北大学金属材料研究所共同研究ワークショップ日本バイオマテリアル学会東北ブロック交流会
- Invited
- Data Source
  KAKENHI-PROJECT-23K17207
[Presentation] A novel approach for pre-implant endothelialization of xenogeneic decellularized vascular tissues by human endothelial cells utilizing tissue surface modification and dynamic culture2022
- Author(s)
  Wen-Jin Ho, Hidetoshi Masumoto, Mako Kobayashi, Kozue Murata, Tadashi Ikeda, Yoshihide Hashimoto, Tsuyoshi Kimura, Kenji Minatoya, Akio Kishida
- Organizer
  American Heart Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04954
[Presentation] 種々の脱細胞化組織由来マトリクス結合型ナノベシクルの評価2022
- Author(s)
  小林真子, 橋本良秀, 根岸淳, 嵯峨秀樹, 佐々木善浩, 秋吉一成, 木村剛, 岸田晶夫
- Organizer
  令和3年度生体医歯工学共同研究拠点成果報告会
- Data Source
  KAKENHI-PROJECT-21K20512
[Presentation] The effect of decellularized tissue-derived hydrogels on cancer cell behavior.2022
- Author(s)
  Mako Kobayashi, Tsuyoshi Kimura, Akio Kishida, Masaya Yamamoto
- Organizer
  The 7th International Symposium on Biomedical Engineering (ISBE2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20512
[Presentation] The effects of matrix-bound nanovesicles (MBVs) derived from high-hydrostatic pressure decellularized tissues on neural regeneration2022
- Author(s)
  Mako Kobayashi, Naoki Ishida, Yoshihide Hashimoto, Jun Negishi, Hideki Saga, Takehiro Iwanaga, Yoshihiro Sasaki, Kazunari Akiyoshi, Tsuyoshi Kimura, Akio Kishida.
- Organizer
  TERMIS-AP
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04954
[Presentation] 種々の脱細胞化組織由来マトリクス結合型ナノベシクル（MBV）の神経再生への効果2022
- Author(s)
  小林真子, 石田直樹, 橋本良秀, 根岸淳, 嵯峨秀樹, 佐々木善浩, 秋吉一成, 山本雅哉, 木村剛, 岸田晶夫
- Organizer
  第12回DDS再生医療研究会・第14回多血小板血漿（PRP）療法研究会
- Data Source
  KAKENHI-PROJECT-21K20512
[Presentation] The effects of matrix-bound nanovesicles (MBVs) derived from high-hydrostatic pressure decellularized tissues on neural regeneration.2022
- Author(s)
  Mako Kobayashi, Naoki Ishida, Yoshihide Hashimoto, Jun Negish, Hideki Saga, Takehiro Iwanaga, Yoshihiro Sasaki, Kazunari Akiyoshi, Tsuyoshi Kimura, Akio Kishida
- Organizer
  TERMIS AP 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20512
[Presentation] 脱細胞化角膜実質足場における角膜上皮・内皮細胞の挙動.2022
- Author(s)
  橋本良秀, 大橋慶子, 萩原萌子, 木村剛，小林尚俊，岸田晶夫.
- Organizer
  第44回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-21H04954
[Presentation] 高静水圧法により作製した脱細胞化組織由来マトリクス結合型ナノベシクル（MBVs）の神経再生への機能評価2022
- Author(s)
  小林真子, 石田直樹, 橋本良秀, 根岸淳, 嵯峨秀樹, 佐々木善浩, 秋吉一成, 木村剛, 岸田晶夫.
- Organizer
  第9回日本細胞外小胞学会学術集会
- Data Source
  KAKENHI-PROJECT-21H04954
[Presentation] 高静水圧法により作製した脱細胞化組織由来マトリクス結合型ナノベシクル（MBVs）の神経再生への機能評価2022
- Author(s)
  小林真子, 石田直樹, 橋本良秀, 根岸淳, 嵯峨秀樹, 佐々木善浩, 秋吉一成, 木村剛, 岸田晶夫
- Organizer
  第9回日本細胞外小胞学会学術集会
- Data Source
  KAKENHI-PROJECT-21K20512
[Presentation] The evaluation of matrix-bound nanovesicles (MBVs) derived from various high-hydrostatic pressure decellularized tissues2021
- Author(s)
  Mako Kobayashi, Yoshihide Hashimoto, Jun Negishi, Hideki Saga, Yoshihiro Sasaki, Kazunari Akiyoshi, Tsuyoshi Kimura, Akio Kishida
- Organizer
  第43回日本バイオマテリアル学会大会第8回アジアバイオマテリアル学会併催
- Data Source
  KAKENHI-PROJECT-21K20512
[Presentation] Extraction of matrix-bound nanovesicles (MBVs) from high-hydrostatic pressure decellularized tissue and evaluation on vascular endothelial cells2021
- Author(s)
  Mako Kobayashi, Naoki Ishida, Yoshihide Hashimoto, Jun Negishi, Hideki Saga, Yoshihiro Sasaki, Kazunari Akiyoshi, Tsuyoshi Kimura, Akio Kishida
- Organizer
  TERMIS-2021(Tissue Engineering and Regenerative Medicine International Society-World Congress2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K20512
[Presentation] 高静水圧法により作製した種々の脱細胞化組織由来マトリクス結合型ナノベシクルの評価2021
- Author(s)
  小林真子, 石田直樹, 橋本良秀, 根岸淳, 嵯峨秀樹, 佐々木善浩, 秋吉一成, 木村剛, 岸田晶夫
- Organizer
  第8回日本細胞外小胞学会学術集会
- Data Source
  KAKENHI-PROJECT-21K20512

1. 岸田晶夫 (60224929)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
2. 木村剛 (10393216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. 橋本良秀 (40638384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
4. 中村奈緒子 (70754878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 佐々木善浩 (90314541)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 山本雅哉 (10332735)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 池田義

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 升本英利

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kobayashi Mako 小林 真子

Research Projects

Research Products

Co-Researchers

Challenges to develop bone-nano tissue engineering using metallic hollow tubes

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞外マトリクスの特性が3Dがん微小環境構築に与える影響の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating the effects of the spatial location and density of cancer cells within the extracellular matrix on cell behavior and function.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of Decellularized Tissue Functions to Obtain Guidelines for Designing Destination Use Devices

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] In Vitro Tissue Reconstruction Using Decellularized Pericardium Cultured with Cells for Ligament Regeneration2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel approach for the endothelialization of xenogeneic decellularized vascular tissues by human cells utilizing surface modification and dynamic culture2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Extraction and Biological Evaluation of Matrix-Bound Nanovesicles (MBVs) from High-Hydrostatic Pressure-Decellularized Tissues2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Preparation of mineralized pericardium by alternative soaking for soft?hard interregional tissue application2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Preparation of bioink containing decellularized tissue powder for 3D cancer microenvironment.2024

Author(s)

Organizer

Data Source

[Presentation] マクロファージ分極を指標と した種々の脱細胞化組織の生体受容性評価.2024

Author(s)

Organizer

Data Source

[Presentation] 3D-cultured cancer spheroid behavior within decellularized extracellular matrix (dECM) powder based bioink.2023

Author(s)

Organizer

Data Source

[Presentation] Freeform Reversible Embedding of Suspended Hydrogel (FRESH) 3D bioprinting using Decellularized Extracellular Matrix (dECM) powder based bio-ink.2023

Author(s)

Organizer

Data Source

[Presentation] 脱細胞化脳・胎盤由来 マトリクス結合型ナノベシクル（MBV）の 抽出と神経機能修復への効果検討2023

Author(s)

Organizer

Data Source

[Presentation] Factors contributing to the functionality of decellularized tissues.2023

Author(s)

Organizer

Data Source

[Presentation] 3D細胞外マトリクス中のがんスフェロイド挙動評価2023

Author(s)

Organizer

Data Source

[Presentation] 細胞外マトリクス環境に着目したがん微小環境構築の検討2023

Author(s)

Organizer

Data Source

Kobayashi Mako 小林真子

[Presentation] マクロファージ分極を指標とした種々の脱細胞化組織の生体受容性評価.2024

[Presentation] 脱細胞化脳・胎盤由来マトリクス結合型ナノベシクル（MBV）の抽出と神経機能修復への効果検討2023