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Yoshimoto Sho  吉本 翔

ORCIDConnect your ORCID iD *help
Researcher Number 70909168
Affiliation (Current) 2025: 麻布大学, 獣医学部, 特命研究員
Affiliation (based on the past Project Information) *help 2024: 麻布大学, 獣医学部, 特命研究員(2024年4月1日~)、特別研究員(~2024年3月31日)
2021 – 2023: 麻布大学, 獣医学部, 学振研究員
Review Section/Research Field
Principal Investigator
Basic Section 42020:Veterinary medical science-related
Except Principal Investigator
Medium-sized Section 42:Veterinary medical science, animal science, and related fields
Keywords
Principal Investigator
CAR-T細胞 / スイッチレセプター / 免疫チェックポイント / 免疫抑制 / 共抑制分子 / 腫瘍 / 遺伝子改変 / イヌ / がん / がん免疫 / PD-1/PD-L1 / 免疫チェックポイント分子 / T細胞の疲弊 … More
Except Principal Investigator
… More 細胞療法 / 遺伝子改変T細胞療法 / 腫瘍免疫 / 腫瘍 / T細胞 / 免疫 / CAR-T細胞 / 腫瘍免疫療法 / 免疫療法 / 固形腫瘍 / 犬 / CAR-T細胞療法 Less
  • Research Projects

    (3 results)
  • Research Products

    (5 results)
  • Co-Researchers

    (3 People)
  •  Development of canine chimeric antigen receptor-T cell with multiple switch receptors to overcome immune suppression within solid tumorPrincipal Investigator

    • Principal Investigator
      吉本 翔
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Azabu University
  •  Investigation of exhaustion-inducing factors and the mechanisms of exhaustion in canine chimeric antigen receptor T cellsPrincipal Investigator

    • Principal Investigator
      Yoshimoto Sho
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Azabu University
  •  犬固形腫瘍に有効なCAR-T細胞のシグナル分子の解明

    • Principal Investigator
      中川 貴之
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 42:Veterinary medical science, animal science, and related fields
    • Research Institution
      The University of Tokyo

All 2024 2023 2022 2021

All Journal Article Presentation

  • [Journal Article] Development and pharmacokinetic assessment of a fully canine anti-PD-1 monoclonal antibody for comparative translational research in dogs with spontaneous tumors2023

    • Author(s)
      Yoshimoto Sho、Chester Nicholas、Xiong Ailian、Radaelli Enrico、Wang Hong、Brillantes Marc、Gulendran Gayathri、Glassman Patrick、Siegel Don L.、Mason Nicola J.
    • Journal Title

      mAbs

      Volume: 15 Issue: 1 Pages: 2287250-2287250

    • DOI

      10.1080/19420862.2023.2287250

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15018, KAKENHI-PROJECT-22KJ2967
  • [Journal Article] Expression of podoplanin in various types of feline tumor tissues2021

    • Author(s)
      KAMOTO Satoshi、SHINADA Masahiro、KATO Daiki、TSUBOI Masaya、YOSHIMOTO Sho、YOSHITAKE Ryohei、ETO Shotaro、IKEDA Namiko、TAKAHASHI Yosuke、HASHIMOTO Yuko、CHAMBERS James、UCHIDA Kazuyuki、YAMADA Shinji、KANEKO Mika K.、NISHIMURA Ryohei、KATO Yukinari、NAKAGAWA Takayuki
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 83 Issue: 11 Pages: 1795-1799

    • DOI

      10.1292/jvms.20-0608

    • NAID

      130008119831

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03141, KAKENHI-PROJECT-21K20614, KAKENHI-PROJECT-20KK0153, KAKENHI-PROJECT-22KJ2967
  • [Presentation] A PD-1/CD28 chimeric switch receptor augments canine chimeric antigen receptor T cell function against PD-L1 expressing target cells2024

    • Author(s)
      Sho Yoshimoto, Antonia Rotolo, Kay Foos, Lauren Olnenick, Satoshi Takagi, Nicola J. Mason
    • Organizer
      World Veterinary Cancer Congress 2024
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15018
  • [Presentation] ヒトへの臨床応用に役立てるためのイヌの腫瘍患者を対象とした CAR-T 細胞の開発と評価2022

    • Author(s)
      吉本 翔、カスパーブライアン、ロトロ アントニア、中川 貴 之、高木 哲、メイソン ニコラ
    • Organizer
      第81回 日本癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-20KK0153
  • [Presentation] Developing and evaluating CAR-T cells for use in canine cancer patients to inform human clinical translation2022

    • Author(s)
      Yoshimoto S, Kasper B, Rotolo A, Nakagawa T, Takagi S, Mason NJ
    • Organizer
      第81回 日本癌学会学術総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15018
  • 1.  中川 貴之 (40447363)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  加藤 大貴 (60843216)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  酒居 幸生 (90844192)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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