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AOYAGI Haruhiko  青柳 東彦

ORCIDConnect your ORCID iD *help
Researcher Number 80037267
Affiliation (based on the past Project Information) *help 2002 – 2003: 長崎大学, 工学部, 教授
1998 – 2000: 長崎大学, 工学部, 教授
1992: Nagasaki University Faculty of Engineering,Professor, 工学部, 教授
1989 – 1991: Kyushu University, Faculty of Science, Associate Professor, 理学部, 助教授
1986 – 1988: Kyushu University, 理学部, 助手
1986: 九大, 理学部, 助手
Review Section/Research Field
Principal Investigator
ポストゲノムのナノサイエンス / Bioorganic chemistry / 天然物有機化学
Except Principal Investigator
天然物有機化学 / 物質生物化学 / 応用微生物学・応用生物化学 / Physical pharmacy
Keywords
Principal Investigator
両親媒性ペプチド / Cultured cells / Transfection / Amphiphilic peptide / Dendrimer / Gene carrier / 培養細胞 / トランスフェクション / デンドリマー / 遺伝子キャリアー … More / galactose modification / nucleic acid carrier / hemolytic activity / lectin / antibacterial activity / phosphilipid membrane / model peptide / amphiphilic peptide / αヘリシティ / β構造 / アミノ酸置換アナログ / DNA細胞内移入 / コンジュゲート / 膜破壊能 / ガラクトース修飾 / 核酸キャリア / 溶血活性 / レクチン / 抗菌活性 / リン脂質膜 / モデルペプチド / 抗菌活性-構造相関 / ペプチドによる蛍光物質漏出 / 両親媒性α-ヘリックス / ペプチド合成 / 抗菌性塩基性ペプチド … More
Except Principal Investigator
cDNA / 抗菌活性 / アミノ酸配列 / ハブ毒 / 遺伝子工学 / アイソザイム / コンホメーション / ペプチド合成 / 環状ペプチド / Peptide synthesis / Chymotrypsin inhibitory peptide / Trypsin inhibitory peptide / Plant inhibitor / Protease inhibitor / 植物起源インヒビター / プロテアーゼインヒビター / トリプシン阻害ペプチド / キモトリプシン阻害ペプチド / トリプトシン阻害ペプチド / 植物起源インヒビタ- / プロテア-ゼインヒビタ- / Energy Calculation / Cyclicpeptide / Conformation / エネルギー計算 / NMR / X-ray crystallography / toxin / hemolysin / self-defense / invertebrate / calcium / carbohydrate-binding protein / lectin / 立体構造 / 溶血活性 / ペプチド / カルシウムイオン / X線結晶構造解析 / 毒素 / 溶血素 / 生体防御 / 無脊椎動物 / カルシウム / 糖結合タンパク質 / レクチン / Amphiphthic / planar bilayer / model peptide / ion channel / 二次構造 / 平面膜法 / Kチャネル / 合成ペプチド / 両親媒性 / 脂質平面膜 / モデルペプチド / イオンチャネル / Zinc protease inhibitor / Zinc proteases / Inhibitor against myolytie factor / Lys-49-phospholipase A_2 / Myolytic factor / Trimeresurus flavoviridis serum inhibitor / Trimeresurus flavoviridis venom enzyme / T_2-プロテア-ゼ結合タンパク質 / T_2-プロテア-ゼ / ハブ毒酵素結合タンパク質 / 脱分極 / N端アミノ酸配列 / 糖タンパク質 / 塩基性タンパク質I結合タンパク質 / ハブ血液 / 筋壊死活性 / 塩基性タンパク質I / 亜鉛プロテアーゼインヒビター / 亜鉛プロテアーゼ / 筋壊死因子インヒビター / 筋壊死因子 / Lys-49-ホスホリパーゼA_2 / ハブ血清インヒビター / ハブ毒酵素 / Physiological activities / Accelerated substitutions / Gene Structures / Expression / cDNAs / Isozymes / Phospholipase A2 / Trimeresurus floavoviridis / ポリモルフィズム / 僞遺伝子 / ゲノム遺伝子 / 発現 / 低活性型Lysー49ーホスホリパ-ゼA_2 / 高活性型Aspー49ーホスホリパ-ゼA_2 / 徳之島ハブ毒 / 融合タンパク質 / 変異タンパク質 / ダーウィン進化 / 分子進化 / 遺伝子 / ホスホリパーゼA_2 / ハブ毒腺 / Genome DNA / Genetic engineering / Isozyme / Phospholipase A_2 / Trimeresurus flavoviridis / イソ酵素 / α→β転位 / アクロモバクタ-プロテア-ゼI / ゲノムDNA / ホスホリパ-ゼA_2 / 奄美ハブ毒 / 植物毒 / 特異構造アミノ酸 Less
  • Research Projects

    (11 results)
  • Co-Researchers

    (12 People)
  •  Analyses of carbohydrate-recognition mechanism of calcium-dependent lectins and its application to construct novel functional proteins

    • Principal Investigator
      HATAKEYAMA Tomomitsu
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      Nagasaki University
  •  Development of easy and high efficient gene transfection using peptide-DNA complexPrincipal Investigator

    • Principal Investigator
      AOYAGI Haruhiko
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      ポストゲノムのナノサイエンス
    • Research Institution
      Nagasaki University
  •  Study on Design of Amphiphilic Functional Peptides and Their Action to Lipid MembranesPrincipal Investigator

    • Principal Investigator
      AOYAGI Haruhiko
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bioorganic chemistry
    • Research Institution
      Nagasaki University
  •  Protein Engineering and Gene Analysis of Trimeresurus flavoviridis Phospholipase A_2 Isozymes

    • Principal Investigator
      OHNO Motonori
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      Kyushu University
  •  Protein Chemistry and Basic Research for Application of Inhibitors from Trimeresurus flavoviridis Serum against Its Venom Enzymes

    • Principal Investigator
      OHNO Motonori
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      天然物有機化学
    • Research Institution
      KYUSHU UNIVERSITY
  •  Synthetic Model Peptides for the Study of Structure-Activity Relationship of Ion Channels Using Planar Lipid Bilayer Technique

    • Principal Investigator
      ANZAI Kazunori
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Kyushu University
  •  Analysis of the Structural Elements Required for Highly Efficient Catalysis

    • Principal Investigator
      OHNO Motonori
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      Kyushu University
  •  Design and Synthesis of Novel Inhibitors Modeled on Plant Protease Inhibitors

    • Principal Investigator
      WAKI Michinori
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      天然物有機化学
    • Research Institution
      Kyushu University
  •  特異構造アミノ酸を含む植物毒環状ペプチドの合成と構造機能相関

    • Principal Investigator
      脇 道典
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      天然物有機化学
    • Research Institution
      Kyushu University
  •  抗グラム陰性菌ペプチドの設計,合成と構造活性相関Principal Investigator

    • Principal Investigator
      青柳 東彦
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      天然物有機化学
    • Research Institution
      Kyushu University
  •  Relationship between Conformation and Primary Structure of Cyclic Tetrahpeptides

    • Principal Investigator
      KATO Tetsuo
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      天然物有機化学
    • Research Institution
      Kyushu University
  • 1.  WAKI Michinori (30037212)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  OHNO Motonori (30038434)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  KATO Tetsuo (20037188)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  SHIMOHIGASHI Yasuyuki (00211293)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  OGAWA Tomohisa (80240901)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  HATTORI Shosaku (00164864)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  ANZAI Kazunori (70128643)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  HATAKEYAMA Tomomitsu (50228467)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  NIIDOME Takuro (20264210)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  広野 修一 (30146328)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KIHARA Hiroshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  OHGA Yoshinobu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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