YAMAGUCHI Tadatoshi 山口忠敏

Researcher Number	80037598
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2011 – 2013: 崇城大学, 薬学部, 教授 2003 – 2004: 宮崎大学, 医学部, 助教授 1996 – 2001: 宮崎医科大学, 医学部, 助教授 1988 – 1991: Dept. of Hygiene, Miyazaki Medical College. Associate Professor, 医学部, 助教授 1986 – 1987: 宮崎医科大学, 講師 1986: 宮崎医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Hygiene / Biological pharmacy / Neurology Except Principal Investigator Environmental pharmacy / 広領域 / Hygiene
Keywords	Principal Investigator dihydropyrazine / DNA strand-breakage / carbon-centered radical / D-glucosamine / TDP Kinase / DNA strand breakage / dihydrodiazepine / diabetes / cultured cell / apoptosis … More Except Principal Investigator ジヒドロピラジン / 糖化反応 / 毒性 / 酸化的ストレス / 糖尿病 / 細胞障害 / HepG2 細胞 / ジヒドロピラジン類 / 細胞障害性 / グルタチオンバランス / 糖化反応中間体 / 遺伝子障害 / アミノ糖 / D-グルコサミン / pBR322プラスミド / DNA切断 / 活性酸素 / マキサム・ギルバート法 / pBR322 / プラスミド / DNA / DNA切断反応 / Dーグルコサミン / 3ーアミノー3ーデオキシアロース / Aminosugars / D-glucosamine / DNA damage / デュシェンヌ型筋ジストロフィー症 / 遺伝性疾患 / 遺伝子診断 / サザンブロット・ハイブリッド法 / 遺伝性筋肉疾患 / パルスフィールドゲル電気泳動 / DMD / PFG / 遺伝子診断制限酵素断片長多型 / RFLP / サザンブロットハイブリダイゼイション / 白血球DNA / Duchenne muscular dystrophy / Genetic disease / genetic diagnosis Less

The involvement of dihydropyrazine-induced gene damage in diabetic complication
- Principal Investigator
  
  ISHIDA TAKUMI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Sojo University
The analysis of onset of familial amyotrophic lateral sclerosis(FALS) with His46Arg point mutationPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Tadatoshi, 大井長和
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  University of Miyazaki
  宮崎医科大学
Basic research in the connection of the cause of development of symptoms of diabetes and its complicationPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Tadatoshi
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Miyazaki Medical College
Dihydropyrazine体による核酸鎖切断作用Principal Investigator
- Principal Investigator
  
  山口忠敏
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  宮崎医科大学
The nutritional attempt to investigate progressive muscular dystrophy with Duchenne type in human.Principal Investigator
- Principal Investigator
  
  YAMAGUCHI Tadatoshi
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Miyazaki Medical College
Genetic Diagnosis of Muscular Dystrophy
- Principal Investigator
  
  FUKAMACHI Seijiro
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Dept. of Hygiene, Miyazaki Medical College.
Amino sugars and their related compounds having nucleic acid- scissoring activity.
- Principal Investigator
  
  WATANABE kenji
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  広領域
- Research Institution
  Fukuoka University

All 2012

All Journal Article Presentation

[Journal Article] Possible involvement of glutathione balance disruption in dihydropyrazine-induced cytotoxicity on human hepatoma HepG2 cells2012
- Author(s)
  Takumi Ishida, Shinji Takechi and Tadatoshi Yamaguchi
- Journal Title
  
  J. Toxicol. Sci
  
  Volume: 37 Pages: 1065-1069
- NAID
  10030876809
- URL
  https://www.jstage.jst.go.jp/browse/jts/37/5/_contents/-char/ja/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590160
[Journal Article] Possible involvement of glutathione balance disruption in dihydropyrazine-induced cytotoxicity on human hepatoma HepG2 cells.2012
- Author(s)
  Takumi Ishida, Shinji Takechi, and tadatoshi Yamaguchi
- Journal Title
  
  Journal of Toxicological Sciences
  
  Volume: 37 Pages: 1065-1069
- NAID
  10030876809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590160
[Presentation] 糖化反応中間体dihydropyrazineによるglutathione balanceへの影響2012
- Author(s)
  石田卓巳, 山口忠敏, 武知進士
- Organizer
  フォーラム2012:衛生薬学・環境トキシコロジー
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590160

1. WATANABE kenji (40078689)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. HAMADA Minoru (90039529)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. NOMURA Hajime (80253839)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. ISHIDA TAKUMI (10301342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. TAKECHI Shinji (10222100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. KASHIGE Nobuhiro (80185751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KAKITA Yukari (80194679)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NAKASHIMA Yukihiko (50164174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SUMOTO Kunihiro (00078677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MIHASHI Kunihide (60078681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. FUKAMACHI Seijiro (90117458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TAKENAKA Hitoshi (10179658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 松本茂信 (70073038)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 大井長和 (80135615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 林田みき枝 (50173050)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAMAGUCHI Tadatoshi 山口 忠敏

Research Projects

Research Products

Co-Researchers

The involvement of dihydropyrazine-induced gene damage in diabetic complication

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The analysis of onset of familial amyotrophic lateral sclerosis(FALS) with His46Arg point mutationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic research in the connection of the cause of development of symptoms of diabetes and its complicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Dihydropyrazine体による核酸鎖切断作用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The nutritional attempt to investigate progressive muscular dystrophy with Duchenne type in human.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genetic Diagnosis of Muscular Dystrophy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Amino sugars and their related compounds having nucleic acid- scissoring activity.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Possible involvement of glutathione balance disruption in dihydropyrazine-induced cytotoxicity on human hepatoma HepG2 cells2012

Author(s)

Journal Title

NAID

URL

Data Source

[Journal Article] Possible involvement of glutathione balance disruption in dihydropyrazine-induced cytotoxicity on human hepatoma HepG2 cells.2012

Author(s)

Journal Title

NAID

Data Source

[Presentation] 糖化反応中間体dihydropyrazineによるglutathione balanceへの影響2012

Author(s)

Organizer

Place of Presentation

Data Source

YAMAGUCHI Tadatoshi 山口忠敏