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HORIIKE Kihachiro  堀池 喜八郎

ORCIDConnect your ORCID iD *help
Researcher Number 80089870
Other IDs
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Affiliation (Current) 2022: 滋賀医科大学, 医学部, 非常勤講師
Affiliation (based on the past Project Information) *help 2001 – 2003: 滋賀医科大学, 医学部, 教授
1998 – 1999: 滋賀医科大学, 医学部, 教授
1995 – 1996: Shiga University of Medical Science, Department of Biochemistry I,Professor, 医学部, 教授
1994: 滋賀医科大学, 医学部, 助教授
1987 – 1991: Shiga University of Medical Science, Associate Professor, 医学部, 助教授
1986: 滋医大, 医学部, 助教授
Review Section/Research Field
Principal Investigator
Pathological medical chemistry / Science and Engineering / 代謝生物化学 / General medical chemistry
Except Principal Investigator
General medical chemistry / Functional biochemistry / Science and Engineering
Keywords
Principal Investigator
カテコール / 酸素添加酵素 / 非ヘム鉄 / D-アミノ酸 / D-アミノ酸酸化酵素 / 中枢神経系 / Astrocyte / フラビン酵素 / D-Amino acid oxidase / Flavoenzyme … More / オキシゲナーゼ / ジオキシゲナーゼ / 二原子酸素添加酵素 / 金属酵素 / 酸素の活性化 / D-セリン / グリア細胞 / 星状グリア細胞 / NMDA受容体 / D-Amino Acid / D-Serine / D-Amino Acid Oxidase / Central Nervous System / Glia / NMDA Receptor / 酵素反応機構 / カテコール2,3-ジオキシゲナーゼ / 酸素活性化 / 置換基効果 / ホモプロトカテク酸 / 結晶構造 / 2,3-ジヒドロキシビフェニール / 電荷移動錯体 / ニトロフェノール / 酵素添加酵素 / カテコール2,3-ジオキゲナーゼ / 酸素分子 / oxygenase / reaction mechanism / non-heme iron / catechol 2,3-dioxygenase / catechol / oxygen activation / substituent effect / homoprotocatechuic acid / 共役過酸化法 / チアゾリジンー2-カルボン酸 / 神経膠細胞 / ベルクマン膠細胞 / 星状膠細胞 / Central nervous system / Thiazolidine-2-carboxylate / Coupled peroxidation method / Neuroglia / ペルオキシソ-ム / D-アミノ酸オキシダ-ゼ / D-アスパラギン酸オキシダ-ゼ / L-α-ヒドロキシ酸オキシダ-ゼ / SH基含有化合物 / Dーアミノ酸オキシダ-ゼ / Dーアスパラギン酸オキシダ-ゼ / Lーαーヒドロキシ酸オキシダ-ゼ / ペルオキシソーム / Dーアミノ酸オキシダーゼ / グリコール酸オキシダーゼ / システアミン / グリオキシル酸 / チアゾリジンー2ーカルボン酸 / Peroxisome / D-Aspartate oxidase / L-alpha-Hydroxy acid oxidase / Sulfhydryl compounds … More
Except Principal Investigator
酸素添加酵素 / ポルフィリン / カテコ-ル1,2一二原子酸素添加酵素 / カテコ-ル2,3一二原子酸素添加酵素 / 3,5ジクロロカテコ-ル1,2ー二原子酸素添加酵素 / 非ヘム鉄酵素 / 遺伝子クロ-ニング / 〇一ニトロフェノ-ル / 電荷移動複合物 / カテコ-ル2,3ー二原子酸素添加酵素 / 非ヘム鉄酸素 / 2,4ージクロロフェノキシ酢酸 / カテコ-ル1,2-二原子酸素添加酵素 / カテコ-ル2,3-二原子酸素添加酵素 / アミノ酸配列 / 塩基配列 / oーニトロフェノ-ル / 電荷移動複合体 / Oxygenase / Catechol 1, 2-dioxygenase / Catechol 2, 3-dioxygenase / 3, 5-Dichlorocatechol dioxygenase / Nonheme iron containing enzyme / omicron-Nitrophenol / Gene cloning / Charge transfer complex / チトクロームc_3 / 硫酸還元細菌 / プレコリン 2 / ウロポルフィリノーゲンIII / コプロポルフィリノーゲンIII / チトクロームC3 / Porphyrin / Cytochrome c3 / Sulfate-reducing bacteria / Precorrin 2 / Uroporphyrinogen III / Coproporphyrinogen III / 硫酸還元菌 / プレコリン / 生合成経路 / S-アデノシルメチオニン / sulfate-reducing bacteria / porphyrin / precorrin-2 / biosynthesis / oxygenase / S-adenosyl-L-methionine / コンポジット生体触媒 / 補酵素 / 構造活性相関 / ピリドキサルリン酸 / コバラミン / フラビン / ヘム / ビルトイン補酵素 / キノヘムプロテイン / composite biocatalyst / coenzyme / structure activity relationship / pyridoxal phosphate / cobalamin / flavin / heme / built-in cofactor Less
  • Research Projects

    (9 results)
  • Co-Researchers

    (15 People)
  •  Molecular Design and Evolution Engineering for Compositc Biochatalysts

    • Principal Investigator
      TORAYA Tetsuo
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      KYOTO UNIVERSITY
  •  Elucidation of the structural and mechanistic basis of pollutants-and signal-transmitter-degrading dioxygenases and their directed evolutionPrincipal Investigator

    • Principal Investigator
      HORIIKE Kihachiro
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      SHIGA UNIVERSITY OF MEDICAL SCIENCE
  •  Elucidation of a novel primitive pathway of aneorobic porphyrin biosynthesis

    • Principal Investigator
      ISHIDA Tetsuo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      Shiga University of Medical Science
  •  カテコール体ジオキシゲナーゼの補因子にはなぜ2価鉄を3価鉄の2種があるのかPrincipal Investigator

    • Principal Investigator
      堀池 喜八郎
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Shiga University of Medical Science
  •  An archaic pathway of porphyrin biosynthesis in prokaryotes

    • Principal Investigator
      SETO Akira
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Shiga University of Medical Science
  •  Does the distribution of free D-serine, which is a potent activator of the NMDA receptor complex, coincide with the localization of D-amino acid oxidase in brains?Principal Investigator

    • Principal Investigator
      HORIIKE Kihachiro
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Shiga University of Medical Science
  •  Comparative biochemical studies on structure, function and physiology of catechol dioxygenases

    • Principal Investigator
      NOZAKI Mitsuhiro
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Shiga University of Medical Science
  •  The Physiological Role of Flavin-dependent Oxidases in Mammalian PeroxisomePrincipal Investigator

    • Principal Investigator
      HORIIKE Kihachiro
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Shiga University of Medical Science
  •  The Physiological Role of D-Amino Acid Oxidase in the Mammalian Central Nervous SystemPrincipal Investigator

    • Principal Investigator
      HORIIKE Kihachiro
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      代謝生物化学
    • Research Institution
      Shiga University of Medical Science
  • 1.  ISHIDA Tetsuo (10176191)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  SANO Seiyo (60025533)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  NOZAKI Mitsuhiro (00025545)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  NAKAI Chieko (30111892)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  SETO Akira (00025636)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  TORAYA Tetsuo (50135597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  HAYASHI Hideyuki (00183913)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  HAYASHI Katsuyuki (20133134)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  TORAYA Tetsuo (70026318)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  SHIMADA Hideo (80095611)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  HIROTSU Ken (10047269)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KIMURA Takahide (70167378)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TANAKA Hiroyuki (10293820)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KITA Akiko (70273430)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  三浦 洌 (70093466)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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