KITAGAWA Takayuki 北川隆之

Researcher Number	80092188
External Links
Affiliation (based on the past Project Information) *help	2013 – 2014: 岩手医科大学, 薬学部, 教授 1999 – 2000: 国立感染症研究所, 細胞化学部, 室長 1997: NATIONAL INSTITUTE OF INFECTIOUS DESEASES (NIID), DEPARTMENT OF BIOCHEMISTRY AND CELL BIOLOGY,LABORATORY CHIEF, 細胞化学部, 室長 1992 – 1996: 国立予防衛生研究所, 細胞化学部, 室長 1995: NATL INST HEALTH,of JAPAN,Laboratory Chief … More 1986 – 1991: 国立予防衛生研究所, 化学部, 室長 1990: Natl. Inst. Hlth, Dept. Chem., Section Chief, 化学部, 化学療法剤室長 1990: 国立予防衛生研究所, 化学部・化学療療剤室長 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Tumor therapeutics Except Principal Investigator Biological pharmacy
Keywords	Principal Investigator 癌抑制遺伝子 / 糖輸送タンパク質 / HUMAN TUMOR CELLS / ヒトがん病態 / MEMBRANE PROTEINS / TUMOR SUPPRESSOR / N-LINKED GLYCOPROTEIN / GLUCOSE TRANSPORTER / カベオリン / N-結合型糖鎖修飾 … More / ヒトがん細胞 / 糖鎖修飾 / GLUT1タンパク質 / グルコース輸送 / がん化学療法 / Cancer chemotherapy / Transformed cells / Calmodulin antagonists / Membrane variant / ATP effect / Membrane permeability / 細胞膜透過性 / 抗癌剤作用の増強 / 膜透過性修飾 / 透過性修飾 / がん細胞 / カルモジュリン阻害剤 / 膜変異株 / ATP作用 / 表面膜透過性 / Caveolin promoter / Transcription Factors / Glucose Transporter / Tumor Suppressor Gene / Membrane Proteins / がん病態 / 脂質臆ドメイン / 脂質膜ドメイン / 転写調節 / 膜タンパク質 / CAVEOLIN / 11番染色体 / グルコース輸送タンパク質 / ヒト融合細胞 / CA VEOLIN / 細胞膜タンパク質 / TUMOR SUPPRESSOR GENE / TGF geta / GROWTH FACTORS / GLYCOSYLATION / GLUT1 PROTEIN / GLUCOSE TRANSPORT / マウス線維芽細胞 / TGF-β / 細胞増殖因子 / 糖輸送 / TGFbeta / グルコース輸送活性 / TGFβ / 増殖因子 / エキソソーム / シグナル伝達 / 化学ライブラリー / 分子標的薬 / がん / がん分子標的薬 / GSK3阻害剤 / 膜たんぱく質 / 糖代謝 / 分子標的治療薬 / 腫瘍生物学 … More Except Principal Investigator CHO cell / LPS / ホスファチジルセリン / phospholipid metabolism / phosphatidylserine / phospholipid-base exchange enzyme / macrophage / enveloped RNA virus / mammalian cell variant / ホスホリパーゼ / ホスファチジルセリン合成系 / 脂質塩基交換反応 / RAW264細胞株 / ホスホリパーゼA_2 / リン脂質代謝 / リン脂質塩基交換酵素 / マクロファージ / 被膜RNAウィルス / CHO細胞株 / 動物細胞変異株 / Phosphatidylserine / Membrane permeability / Macrophage / Mutant / Phospholipid / Mammalian cells / ホスホリパ-ゼA_2 / アラキドン酸 / ホスファチジルイノシト-ル / スフィンゴミエリン / 細胞表面膜透過性 / マクロファ-ジ系細胞 / CHO細胞 / 変異株 / リン脂質 / 動物細胞 Less

Searching for new types of anti-cancer agents which modulate glucose transporter expressionPrincipal Investigator
- Principal Investigator
  
  KITAGAWA Takayuki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor therapeutics
- Research Institution
  Iwate Medical University
Functional analysis in the search for a putative tumor suppressor gene based upon the changes in the expression of membrane proteins in human tumor cellsPrincipal Investigator
- Principal Investigator
  
  KITAGAWA Takayuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Infectious Diseases
Molecular mechanisms for mammalian glucose transporter expression and its function associated with human tumorigenesis.Principal Investigator
- Principal Investigator
  
  KITAGAWA Takayuki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Infectious Diseases, Tokyo, Japan.
MOLECULAR MECHANISMS FOR REGULATION OF MAMMALIAN GLUCOSE TRANSPORTER EXPRESSION AND ITS FUNCTIONPrincipal Investigator
- Principal Investigator
  
  KITAGAWA Takayuki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  NATIONAL INSTITUTE OF HEALTH,JAPAN
REGULATION OF GLUCOSE TRANSPORT AND GLUCOSE TRANSPORTER GENE EXPRESSION BY GRAWTH FACTORS IN ANIMAL CELLSPrincipal Investigator
- Principal Investigator
  
  KITAGAWA Takayuki
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  NATIONAL INSTITUTE OF HEALTH
Studies on the regulatory mechanisms and the biological significance of metabolisms of membrane phospholipids in mammalian cells by using technics of biochemical genetics.
- Principal Investigator
  
  AKAMATSU Yuzuru
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Health, Japan
Control of Membrane Permeability by External ATP in Animal Cells And its Application to Cancer ChemotherapyPrincipal Investigator
- Principal Investigator
  
  KITAGAWA Takayuki
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  国立予防衛生研究所
Studies on the regulatory mechanisms of phospholipid metabolism and membrane functions by using cultured mammalian cell variants defective in phospholipid biosynthesis.
- Principal Investigator
  
  AKAMATSU Yuzuru
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Health, Japan

All 2015 2014 2013 2000 1999 Other

All Journal Article Presentation

[Journal Article] A new cationic liposome for efficient gene delivery with serum into cultured human cells : a quantitative analysis using two fluorescent probes.2000
- Author(s)
  T.Serikawa, T.Kitagawa, 他3名
- Journal Title
  
  Biochim.Biophys.Acta 1467
  
  Pages: 419-430
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-11672205
[Journal Article] A new cationic liposome for efficient gene delivery with serum into cultured human cells : a quantitative analysis using two independent fluorescent probes.2000
- Author(s)
  T.Serikawa, T.Kitagawa, et al.
- Journal Title
  
  Biochim.Biophys.Acta 1467
  
  Pages: 419-430
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-11672205
[Journal Article] Enhanced expression of Glut3 in tumorigenic Hela cell hybrids associated with tumor suppressor dysfunction.1999
- Author(s)
  T.Suzuki, T.Kitagawa, 他5名
- Journal Title
  
  Eur.J.Biochem. 262
  
  Pages: 534-540
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-11672205
[Journal Article] Enhanced expression of Glut3 in tumorigenic Hela cell hybrids associated with tumor suppressor dysfunction.1999
- Author(s)
  T.Suzuki, T.Kitagawa, et al.
- Journal Title
  
  Eur.J.Biochem. 262
  
  Pages: 534-540
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-11672205
[Presentation] ヒト大腸癌細胞におけるGSK3inhibitorⅨの有効性検討2015
- Author(s)
  及川亜美、佐京智子、奈良場博昭、北川隆之
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学ほか(兵庫県・神戸市）
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-25640092
[Presentation] GSK3 阻害剤の in vivo 抗腫瘍効果と GLUT3 発現抑制2015
- Author(s)
  大久保美希、藤盛真衣、榎本俊介、佐京智子、奈良場博昭、北川隆之
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学ほか(兵庫県・神戸市）
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-25640092
[Presentation] GSK3阻害剤によるヒト大腸がん由来Caco-2細胞の増殖抑制とGLUT3発現抑制2014
- Author(s)
  佐京智子, 佐々木かな恵, 三浦佳奈子, 川口未央, 奈良場博昭, 北川隆之
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25640092
[Presentation] in vivoにおけるGSK3阻害剤の腫瘍抑制効果及びGLUT3発現抑制の検討2014
- Author(s)
  榎本俊介、佐京智子、川口未央、奈良場博昭、北川隆之
- Organizer
  第53回日本薬学会東北支部大会
- Place of Presentation
  いわき明星大学キャンパス(福島県・いわき市）
- Year and Date
  2014-10-05
- Data Source
  KAKENHI-PROJECT-25640092
[Presentation] Caco-2細胞におけるGSK-3阻害剤のGLUT3発現抑制と細胞増殖抑制2014
- Author(s)
  三浦佳奈子、佐々木かな恵、佐京智子、川口未央、奈良場博昭、北川隆之
- Organizer
  日本生化学会東北支部第80例会・シンポジウム
- Place of Presentation
  秋田パークホテル(秋田県・秋田市）
- Year and Date
  2014-05-10
- Data Source
  KAKENHI-PROJECT-25640092
[Presentation] GSK3阻害剤のin vivo抗腫瘍効果とGLUT3発現抑制の検討2014
- Author(s)
  藤盛真衣、佐京智子、奈良場博昭、川口未央、北川隆之
- Organizer
  第53回日本薬学会東北支部大会
- Place of Presentation
  いわき明星大学キャンパス(福島県・いわき市）
- Year and Date
  2014-10-05
- Data Source
  KAKENHI-PROJECT-25640092
[Presentation] 糖輸送タンパク質を分子標的とする新規抗がん治療薬の探索2013
- Author(s)
  北川隆之、佐京智子、渡辺勝
- Organizer
  第17回日本がん分子標的治療学会・学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25640092
[Presentation] 糖輸送タンパク質を分子標的とする新規抗がん治療薬の探索2013
- Author(s)
  北川隆之、渡辺勝、佐京智子、川口未央、奈良場博昭
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25640092
[Presentation] Caco-2細胞におけるGSK3阻害剤によるGLUT3発現と増殖阻害
- Author(s)
  佐々木かな恵、佐京智子、川口未央、奈良場博昭、北川隆之
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25640092

1. AKAMATSU Yuzuru (00072900)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. AMANO Fumio (90142132)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. NISHIJIMA Nasahiro (60072956)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KUZE Yohko (50178000)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TANAKA Yasuhito (30113484)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. KUGE Osamu (30177977)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. SAKYO Tomoko (00405755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
8. MASUMI Atsuko (70165728)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YAMAKAWA Yoshio (50100102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SUZUKI Toshikazu (70270527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. IWAZAKI Ayano

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KITAGAWA Takayuki 北川 隆之

Research Projects

Research Products

Co-Researchers

Searching for new types of anti-cancer agents which modulate glucose transporter expressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis in the search for a putative tumor suppressor gene based upon the changes in the expression of membrane proteins in human tumor cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms for mammalian glucose transporter expression and its function associated with human tumorigenesis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MOLECULAR MECHANISMS FOR REGULATION OF MAMMALIAN GLUCOSE TRANSPORTER EXPRESSION AND ITS FUNCTIONPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

REGULATION OF GLUCOSE TRANSPORT AND GLUCOSE TRANSPORTER GENE EXPRESSION BY GRAWTH FACTORS IN ANIMAL CELLSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the regulatory mechanisms and the biological significance of metabolisms of membrane phospholipids in mammalian cells by using technics of biochemical genetics.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Control of Membrane Permeability by External ATP in Animal Cells And its Application to Cancer ChemotherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the regulatory mechanisms of phospholipid metabolism and membrane functions by using cultured mammalian cell variants defective in phospholipid biosynthesis.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A new cationic liposome for efficient gene delivery with serum into cultured human cells : a quantitative analysis using two fluorescent probes.2000

Author(s)

Journal Title

Description

Data Source

[Journal Article] A new cationic liposome for efficient gene delivery with serum into cultured human cells : a quantitative analysis using two independent fluorescent probes.2000

Author(s)

Journal Title

Description

Data Source

[Journal Article] Enhanced expression of Glut3 in tumorigenic Hela cell hybrids associated with tumor suppressor dysfunction.1999

Author(s)

Journal Title

Description

Data Source

[Journal Article] Enhanced expression of Glut3 in tumorigenic Hela cell hybrids associated with tumor suppressor dysfunction.1999

Author(s)

Journal Title

Description

Data Source

[Presentation] ヒト大腸癌細胞におけるGSK3inhibitorⅨの有効性検討2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] GSK3 阻害剤の in vivo 抗腫瘍効果と GLUT3 発現抑制2015

Author(s)

KITAGAWA Takayuki 北川隆之