HAYASHI FUMIO 林文夫

… Alternative Names

Researcher Number	80093524
Other IDs
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Affiliation (Current)	2020: 神戸大学, 理学研究科, 名誉教授
Affiliation (based on the past Project Information) *help	2017 – 2020: 神戸大学, 理学研究科, 名誉教授 2017: 神戸大学, 大学院理学系研究科, 名誉教授 2014 – 2016: 神戸大学, 理学(系)研究科(研究院), 名誉教授 2007: Kobe University, Graduate Sch. Sci., Biology, Professor 2000 – 2006: 神戸大学, 理学部, 教授 … More
Review Section/Research Field	Principal Investigator Biophysics / Nanomaterials/Nanobioscience / Functional biochemistry / 分子遺伝学・分子生理学 / 広領域 Except Principal Investigator Biophysics / Basic Section 43040:Biophysics-related / 分子遺伝学・分子生理学 / Constructive Systems Biology
Keywords	Principal Investigator cGMP / 視細胞 / photoreceptor / phosphodiesterase / phosphorylation / G蛋白質 / G protein / phosphatidylinositol / トランスデューシン / transducin … More Except Principal Investigator 人工膜 / 生体膜 / 膜タンパク質 / 受容体 / 脂質ラフト / ロドプシン / GPCR / ラフト / ロドプシン光受容体 / イノシトールリン脂質 / タンパク質リン酸化酵素 / チロシンキナーゼ / 阻害剤 / ポリホスホイノシチド / ウシガエル / 視細胞外節膜 / 情報変換機構 / カルシウム / GTP結合タンパク質 / ホスホリパーゼC / イノシトール3リン酸 / Phototransduction / Phosphoinositides / Phospholipase C / Calcium / GTP-binding protein / Inositoltrisphosphate / Frog / 光シグナル伝達 / 擬結晶 / 2次元秩序構造 / Gタンパク質共役型受容体 / GPIアンカー型タンパク質 / ナノ空間 / 1分子計測 / ナノ流路 / 光受容体 / 高速原子間力顕微鏡 / バイオイメージング Less

光受容体タンパク質が形成する超分子構造とシグナル伝達の分子動態機構の解明Ongoing
- Principal Investigator
  
  山下隼人
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Osaka University
Measuring molecular properties of membrane proteins using a synthetic cell micro-environment conposed of a model cell membrane and a nanometric spaceOngoing
- Principal Investigator
  
  森垣憲一
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Kobe University
光受容体タンパク質が自発的に作る2次元秩序構造についての構成的研究Ongoing
- Principal Investigator
  
  森垣憲一
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Constructive Systems Biology
- Research Institution
  Kobe University
Evaluating the affinity of membrane proteins and lipid raft using a patterned model membrane platformOngoing
- Principal Investigator
  
  森垣憲一
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Kobe University
Model biological membrane having a nanometric gap structure
- Principal Investigator
  
  Morigaki Kenichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biophysics
- Research Institution
  Kobe University
Evaluating the raftophilicity of membrane proteins in a patterned model membrane
- Principal Investigator
  
  Morigaki Kenichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Kobe University
Single Molecular Biochemistry of The Operating Mechanism of Photoreoeptor G protein and its Trafficking Mechanism.Principal Investigator
- Principal Investigator
  
  HAYASHI Fumio
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  Kobe University
Single Molecular Biochemistry of G protein signaling system in photoreceptor cellPrincipal Investigator
- Principal Investigator
  
  HAYASHI Fumio
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  Kobe University
特殊な両親媒性物質による表在性膜蛋白質の選択的可溶化Principal Investigator
- Principal Investigator
  
  林文夫
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  Kobe University
Regulation of Photo-Chemical Signal Transduction in Photoreceptor by Cdk5 and PhosphatasePrincipal Investigator
- Principal Investigator
  
  HAYASHI Fumio
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  広領域
- Research Institution
  Kobe University
光情報を伝達する低分子量G-タンパク質の性質と機能Principal Investigator
- Principal Investigator
  
  林文夫
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biophysics
- Research Institution
  Kobe University
Molecular mechanisms underlying the high temporal resolution of photoreceptors.Principal Investigator
- Principal Investigator
  
  HAYASHI Fumio
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  KOBE UNIVERSITY
視細胞光依存性cGMP加水分解酵素阻害サブユニットのリン酸化と明順応Principal Investigator
- Principal Investigator
  
  林文夫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Kobe University
Regulation mechanisms of visual excitationPrincipal Investigator
- Principal Investigator
  
  HAYASHI Fumio
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  Kobe University
細胞増殖・がん化に伴うイノシトールリン脂質キナーゼの変化とチロシンキナーゼの役割
- Principal Investigator
  
  深見泰夫
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kobe University
The role of phosphoinositides in vertebrate phototransduction mechanism.
- Principal Investigator
  
  AMAKAWA Taisaku
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  Kobe University

All 2019 2018 2017 2016 2015 2007 Other

All Journal Article Presentation

[Journal Article] Inhibitory effect of several sphingolipid metabolites on calcineurin2018
- Author(s)
  Maruyama Yoko、Ueno Satoko、Morita Mitsuhiro、Hayashi Fumio、Maekawa Shohei
- Journal Title
  
  Neuroscience Letters
  
  Volume: 673 Pages: 132-135
- DOI
  10.1016/j.neulet.2018.03.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17KT0024, KAKENHI-PROJECT-17H03666, KAKENHI-PROJECT-26430071, KAKENHI-PROJECT-17K07110, KAKENHI-PROJECT-18KT0071
[Journal Article] Palmitoylation is a prerequisite for dimerization-dependent raftophilicity of rhodopsin2017
- Author(s)
  Seno Keiji、Hayashi Fumio
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 292 Pages: 15321-15328
- DOI
  10.1074/jbc.m117.804880
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17KT0024, KAKENHI-PROJECT-17H03666
[Journal Article] The Role of the Prod1 Membrane Anchor in Newt Limb Regeneration2017
- Author(s)
  Nomura, K., Tanimoto, Y., Hayashi, F., Harada, E., Shan, X.-Y., Shionyu, M., Hijikata, A., Shirai, T., Morigaki, K., Shimamoto, K.
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 56 Pages: 270-274
- DOI
  10.1002/anie.201609703
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26291031, KAKENHI-PROJECT-15K00411, KAKENHI-PROJECT-15K14489, KAKENHI-PROJECT-15K21487, KAKENHI-PROJECT-17KT0024, KAKENHI-PROJECT-17H03666
[Journal Article] Dynamic changes in the interchromosomal interaction of early histone gene loci during development of sea urchin2017
- Author(s)
  Matsushita Masaya、Ochiai Hiroshi、Suzuki Ken-ichi T.、Hayashi Sayaka、Yamamoto Takashi、Awazu Akinori、Sakamoto Naoaki
- Journal Title
  
  Journal of Cell Science
  
  Volume: 130 Pages: 4097-4107
- DOI
  10.1242/jcs.206862
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17KT0024, KAKENHI-PROJECT-17K05614, KAKENHI-PROJECT-17K07241
[Journal Article] Hybrid model membrane combining micropatterned lipid bilayer and hydrophilic polymer brush2017
- Author(s)
  Nishimura Toshiki、Tamura Fuyuko、Kobayashi Sawako、Tanimoto Yasushi、Hayashi Fumio、Sudo Yuki、Iwasaki Yasuhiko、Morigaki Kenichi
- Journal Title
  
  Langmuir
  
  Volume: 33 Pages: 5752-5759
- DOI
  10.1021/acs.langmuir.7b00463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17KT0024, KAKENHI-PUBLICLY-17H05726, KAKENHI-PLANNED-25104005, KAKENHI-PROJECT-15H04363, KAKENHI-PROJECT-17H03666, KAKENHI-PROJECT-17J02031, KAKENHI-PROJECT-15K14489, KAKENHI-PROJECT-17K20119
[Journal Article] Evaluating the raftophilicity of rhodopsin photoreceptor in a patterned model membrane2015
- Author(s)
  Tanimoto, Y., Okada, K., *Hayashi, F., Morigaki, K.
- Journal Title
  
  Biophysical Journal
  
  Volume: 109 Pages: 2307-2316
- DOI
  10.1016/j.bpj.2015.10.015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K14489, KAKENHI-PROJECT-25286062, KAKENHI-PROJECT-26291031
[Presentation] Self-spreading of a phospholipid bilayer in the scaffold of polymerized lipid bilayer2019
- Author(s)
  Kenichi Morigaki, Fuyuko Tamura, Yasushi Tanimoto, Rurika Nagai, Misato Yamada, Fumio Hayashi
- Organizer
  257th ACS National Meeting and Exposition
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03666
[Presentation] 網膜桿体細胞内円盤膜上での脂質-光受容タンパク質秩序形成の数理モデル2019
- Author(s)
  金重先人, 谷本泰士, 西森拓, 林文夫, 森垣憲一, 粟津暁紀
- Organizer
  日本物理学会 2019春季大会
- Data Source
  KAKENHI-PROJECT-17KT0024
[Presentation] Self-spreading of a phospholipid bilayer in the scaffold of polymerized lipid bilayer2019
- Author(s)
  Kenichi Morigaki, Fuyuko Tamura, Yasushi Tanimoto, Rurika Nagai, Misato Yamada, Fumio Hayashi
- Organizer
  257th ACS National Meeting and Exposition
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0024
[Presentation] Raftophilicity and aggregation of membrane proteins in the photo-transduction2018
- Author(s)
  Kenichi Morigaki, Yasushi Tanimoto, Hayato Yamashita, Akinori Awazu, Fumio Hayashi
- Organizer
  日本生物物理学会第56回年会
- Invited
- Data Source
  KAKENHI-PROJECT-17KT0024
[Presentation] Raftophilicity and aggregation of membrane proteins in the photo-transduction2018
- Author(s)
  Kenichi Morigaki, Yasushi Tanimoto, Hayato Yamashita, Akinori Awazu, Fumio Hayashi
- Organizer
  第56回年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03666
[Presentation] Observing the interaction between rhodopsin cluster and transducin by high-speed AFM2018
- Author(s)
  Y. Tanimoto, H. Yamashita, K. Nomura, M. Abe, F. Hayashi, K. Morigaki
- Organizer
  日本生物物理学会第56回年会
- Data Source
  KAKENHI-PROJECT-17KT0024
[Presentation] A mathematical model of pattern formation of lipid-photoreceptor protein on disk membrane o retinal cells2018
- Author(s)
  金重先人, 谷本泰士, 西森拓, 林文夫, 森垣憲一, 粟津暁紀
- Organizer
  日本生物物理学会第56回年会
- Data Source
  KAKENHI-PROJECT-17KT0024
[Presentation] 網膜桿体細胞内円盤膜上での脂質-光受容タンパク質秩序形成の数理モデル2018
- Author(s)
  金重先人, 谷本泰士, 西森拓, 林文夫, 森垣憲一, 粟津暁紀
- Organizer
  定量生物学会
- Data Source
  KAKENHI-PROJECT-17KT0024
[Presentation] Reconstitution and quantitative analyses of membrane signal transduction by using micropatterned model system2017
- Author(s)
  Morigaki, K., Tanimoto, Y., Kojima, S., Awazu, A., Hayashi, F.
- Organizer
  ConBio 2017
- Invited
- Data Source
  KAKENHI-PROJECT-17KT0024
[Presentation] Hybrid model membrane combining micropatterned lipid bilayer and hydrophilic polymer brush2017
- Author(s)
  Morigaki, K., Nishimura, T., Tamura, F., Kobayashi, S., Tanimoto, Y., Sudo, Y., Hayashi, F., Iwasaki, K.
- Organizer
  253rd American Chemical Society National Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03666
[Presentation] Hybrid model membrane combining micropatterned lipid bilayer and hydrophilic polymer brush2017
- Author(s)
  Morigaki, K., Nishimura, T., Tamura, F., Kobayashi, S., Tanimoto, Y., Sudo, Y., Hayashi, F., Iwasaki, K.
- Organizer
  253rd American Chemical Society National Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0024
[Presentation] Hybrid model membrane combining micropatterned lipid bilayer and hydrophilic polymer brush2017
- Author(s)
  Morigaki, K., Nishimura, T., Tamura, F., Kobayashi, S., Tanimoto, Y., Sudo, Y., Hayashi, F., Iwasaki, K.
- Organizer
  253rd American Chemical Society National Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14489
[Presentation] Reconstitution and quantitative analyses of membrane signal transduction by using micropatterned model system2017
- Author(s)
  Morigaki, K., Tanimoto, Y., Kojima, S., Awazu, A., Hayashi, F.
- Organizer
  ConBio 2017
- Invited
- Data Source
  KAKENHI-PROJECT-15K14489
[Presentation] Reconstitution and quantitative analyses of membrane signal transduction by using micropatterned model system2017
- Author(s)
  Morigaki, K., Tanimoto, Y., Kojima, S., Awazu, A., Hayashi, F.
- Organizer
  ConBio 2017
- Invited
- Data Source
  KAKENHI-PROJECT-17H03666
[Presentation] Evaluating the raftophilicity of rhodopsin photoreceptor in a patterned model membrane2016
- Author(s)
  Morigaki, K., Tanimoto, Y., Hayashi, F.
- Organizer
  251st American Chemical Society National Meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-03-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291031
[Presentation] Evaluating the raftophilicity of rhodopsin photoreceptor in a patterned model membrane2016
- Author(s)
  Morigaki, K., Tanimoto, Y., Hayashi, F
- Organizer
  251st American Chemical Society National Meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-03-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14489
[Presentation] パターン化モデル生体膜を用いた、光シグナル伝達に関わる膜タンパク質の脂質ラフト親和性解析2015
- Author(s)
  谷本泰士、小嶋佐妃子、森垣憲一、林文夫
- Organizer
  第53 回日本生物物理学会年会
- Place of Presentation
  金沢大学
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-26291031
[Presentation] ロドプシンはラフト親和性の短寿命ナノドメインを形成しながら拡散している2015
- Author(s)
  林文夫、齋藤夏美、谷本泰士、森垣憲一、妹尾圭司
- Organizer
  第53 回日本生物物理学会年会
- Place of Presentation
  金沢大学
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-26291031
[Presentation] valuating the raftophilicity of rhodopsin in a patterned model membrane2015
- Author(s)
  Tanimoto, Yasushi; Hayashi, Fumio; Morigaki, Kenichi
- Organizer
  2015 International Chemical Congress of Pacific Basin Societies (Pacifichem 2015)
- Place of Presentation
  Honolulu, USA
- Year and Date
  2015-12-15
- Data Source
  KAKENHI-PROJECT-26291031
[Presentation] Frog photoreceptor rhodopsin is recruited to the raft upon dimerization2007
- Author(s)
  Keiji, Seno, Fumio, Hayashi
- Organizer
  The Biophysical Society of Japan, Annual Meeting
- Place of Presentation
  at Pcifico Yokohama
- Year and Date
  2007-12-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18310088
[Presentation] カエル視細胞のロドプシンは二量体化によって脂質ラフトへ移行する2007
- Author(s)
  妹尾圭司、林文夫
- Organizer
  日本生物物理学会第45回年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18310088
[Presentation] Single Molecule Tracking of Transducin and Rhodopsin in Rod Photoreceptor Disk Membranes2007
- Author(s)
  Fumio, Hayashi, Shibata, Nobuyuki, Toshi, Takahashi, Keiji, Seno
- Organizer
  The Biophysical Society of Japan, Annual Meeting
- Place of Presentation
  at Pcifico Yokohama
- Year and Date
  2007-12-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18310088
[Presentation] 視細胞円板膜上でのトランスデューシン及びロドプシンの一分子追跡2007
- Author(s)
  林文夫, 他4名
- Organizer
  日本生物物理学会第45回年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18310088
[Presentation] モデル生体膜を用いたロドプシン光受容体の脂質ラフト親和性解析
- Author(s)
  谷本　泰士, 森垣　憲一, 林　文夫
- Organizer
  第52回日本生物物理学会年会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26291031

1. Morigaki Kenichi (10358179)

# of Collaborated Projects: 6 results

# of Collaborated Products: 23 results
2. 鈴木健一 (50423059)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 笠井倫志 (20447949)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 山下隼人 (10595440)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 粟津暁紀 (00448234)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. AMAKAWA Taisaku (70031359)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 深見泰夫 (00156746)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SHIONYU Masafumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 森田光洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 土方敦司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 坂本尚昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 須藤雄気

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 岩崎泰彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HAYASHI FUMIO 林 文夫

Hayashi Fumio 林 文夫

HAYASHI Fumio 林 文夫

Research Projects

Research Products

Co-Researchers

光受容体タンパク質が形成する超分子構造とシグナル伝達の分子動態機構の解明Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Measuring molecular properties of membrane proteins using a synthetic cell micro-environment conposed of a model cell membrane and a nanometric spaceOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

光受容体タンパク質が自発的に作る2次元秩序構造についての構成的研究Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluating the affinity of membrane proteins and lipid raft using a patterned model membrane platformOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Model biological membrane having a nanometric gap structure

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluating the raftophilicity of membrane proteins in a patterned model membrane

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Single Molecular Biochemistry of The Operating Mechanism of Photoreoeptor G protein and its Trafficking Mechanism.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Single Molecular Biochemistry of G protein signaling system in photoreceptor cellPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

特殊な両親媒性物質による表在性膜蛋白質の選択的可溶化Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of Photo-Chemical Signal Transduction in Photoreceptor by Cdk5 and PhosphatasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

光情報を伝達する低分子量G-タンパク質の性質と機能Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms underlying the high temporal resolution of photoreceptors.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

視細胞光依存性cGMP加水分解酵素阻害サブユニットのリン酸化と明順応Principal Investigator

Principal Investigator

HAYASHI FUMIO 林文夫

Hayashi Fumio 林文夫

HAYASHI Fumio 林文夫