FUJIWARA KENJI 藤原研司

… Alternative Names

Researcher Number	80101088
Other IDs
External Links
Affiliation (Current)	2022: 独立行政法人労働者健康安全機構横浜労災病院(臨床病態研究センター), 臨床病態研究センター, 名誉院長
Affiliation (based on the past Project Information) *help	1994 – 2004: 埼玉医科大学, 医学部, 教授 1998: Saitama Medical School, Faculty of Medicine, Professor and Chairman, 医学部, 教授 1995: Saitama medical school : professor, 附属病院, 教授 1992 – 1993: 東京大学, 医学部(病), 講師 1990: University of Tokyo, Faculty of Medicine, Lecturer., 医学部・附属病院, 講師 … More
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator Gastroenterology
Keywords	Principal Investigator 劇症肝炎 / 肝再生 / Osteopontin / 肝細胞膜 / liver regeneration / クッパー細胞 / 類洞内皮細胞 / 肝移植 / 肝類洞内皮細胞 / VEGF … More Except Principal Investigator VEGF / COX-2 / 肝再生 / 肝細胞 / 肝類洞内皮細胞 / TFPI / 肝星細胞 / PCPE / PDGF / KDR / flk-1 / Liver Regeneration / TNF / NFκB / マクロファージ / プロスタグランジン / PPAR / prostaglandin / 上皮成長因子 / 肝細胞膜 / 細胞増殖 / 肝細胞増殖 / 蛋白 / hepatocytes / plasma membrane / cell growth / 肝移植 / 肝不全 / トロンボモジュリン / 類洞内皮細胞 / Liver transplantation / Liver failure / Sinusoidal endothelial cell / Thrombomodulin / RNA結合蛋白 / 平滑筋αアクチン / コラゲン / bFGF / TGFβ / Hepatic Stellate Cell / RNA-binding Protein / Smooth Muscle α Actin / 劇症肝炎 / flt-1 / fet-1 / Fulminant Hepatic Failure / Sinusoidal Endothelial Cells / ft-1 / アポトーシス / IAP(inhibitor of apoptosis) / D-galactosamine / エンドトキシン / 肝壊死 / apoptosis / IAP (inhibitor of apoptosis protein) / hepatocyte / macrophage / 大腸癌 / 大腸腺腫 / 受容体 / 血管内皮増殖因子 / PPARγ / colon cancer / CIX-2 / 胃過形成性ポリープ / 胃腺腫 / ヘリコバクター・ピロリ / cDNAマイクロアレイ / 血管新生 / 癌化 / 胃癌 / gastric hyperplastic polyp / gastric adenoma / Helicobacter pylori / cDNA microarray / angiogenesis / carcinogenesis / 急性肝不全 / グルカゴン・インスリン療法 / 血漿交換 / 抗トロンビン【III】 / オルニチンデカルボキシラーゼ / プロスタグランヂン誘導体 / 肝障害 / 交換輸血 / 血管内凝固 / アンチトロンビン【III】 / インスリン・グルカゴン療法 / Acute liver failure / Liver regeneration / Cytoprotection / Exchange transfusion / Glucagon / Insulin / Ornithine decarboxylase / 増殖因子 / 血小板 / イムノアッセイ / Epidermal Growth Factor / Growth Factor / Platelet Less

Genetic Polymorphisms in Promoter Regions of Osteopontin Gene as Host Factors to Determine Th1 Immune Reactions against Hepatitis Virus.Principal Investigator
- Principal Investigator
  
  FUJIWARA Kenji
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Saitama Medical School
Role of COX-2 in the development of gastric tumor by Helicobacter Pylori
- Principal Investigator
  
  ARAI Shin
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Saitama Medical School
Roles of cell surface membrane and nuclear prostaglandin receptors in growth factor production during colon carcinogenesis
- Principal Investigator
  
  OTA Shinichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Saitama Medical School
Study on Strategies for Non-Heart Beating LiverPrincipal Investigator
- Principal Investigator
  
  FUJIWARA Kenji
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Saitama Medical School
Mechanisms of Development of Massive Necrosis and Regeneration after Liver Injury Regulated by Activated Sinusoidal Macrophages
- Principal Investigator
  
  NAGOSHI Sumiko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Saitama Medical School
The Mechanisms of Hepatic Stellate Cell Activation : Possible Contribution of Type I Procollagen C-Proteinase Enhancer Protein.
- Principal Investigator
  
  MATSUI Atsushi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Saitama Medical School
The Mechanisms of Impaired Liver Regeneration in Fulminant Hepatic Failure : The Significance of Sinusoidal Endothelial Cell Proliferation.
- Principal Investigator
  
  MOCHIDA Satoshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Saitama Medical School
Anticoagulant Targeting the Hepatic Sinusoids for Liver Injury Following Orthotopic Liver Transplantation
- Principal Investigator
  
  MOCHIDA Satoshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Saitama Medical School
New devices in anticoagulant therapy for massive hepatic necrosis through sinusoidal fibrin depositionPrincipal Investigator
- Principal Investigator
  
  FUJIWARA Kenji
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Saitama Medical School
purification of growth stimulatory factor in rat liver plasma membrane
- Principal Investigator
  
  HIRATA Keiichi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tokyo
Purification of hepatocyte comitogenic factor in plasma membrane and its action site (s) in hepatocyte proliferation.Principal Investigator
- Principal Investigator
  
  FUJIWARA Kenji
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tokyo
Factors Associated with Insufficient Liver Regeneration in Fulminant Hepatic FailurePrincipal Investigator
- Principal Investigator
  
  FUJIWARA Kenji
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tokyo
Platelet Epidermal Growth Factor and Liver Regeneration
- Principal Investigator
  
  IKEDA Hitoshi, 岡裕爾
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tokyo
ROLE OF SUPEROXIDE FROM MACROPHAGES IN HEPATIC FIBROSISPrincipal Investigator
- Principal Investigator
  
  FUJIWARA Kenji
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tokyo
TREATMENT OF ACUTE LIVER FAILURE BY STIMULATION OF LIVER REGENERATION AND CYTOPROTECTION
- Principal Investigator
  
  OKA Hiroshi
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo University

All 2004 2003 Other

All Journal Article Patent

[Journal Article] Plasma Osteopontin Levels in Patients with Fulminant Hepatitis2004
- Author(s)
  Matsui A, Mochida S, Ohno A, Nagoshi S, Hirose T, Fujiwara K
- Journal Title
  
  Hepatology Res 22
  
  Pages: 202-206
- NAID
  10018024812
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370191
[Journal Article] Genetic Polymorphisms in Promoter Region of Osteopontin Gene May be a Marker Reflecting Hepatitis Activity in Chronic Hepatitis C Patients2004
- Author(s)
  Mochida S, Hashimoto M, Matsui A, Naito M, Inao M, Nagoshi S, Egashira T, Mishiro S, Fujiwara K
- Journal Title
  
  Biochem Biophys Res Commun 313
  
  Pages: 1079-1085
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370191
[Journal Article] Transgenic Mice Expressing Osteopontin in Hepatocytes as a Model of Autoimmune Hepatitis2004
- Author(s)
  Mochida S, Yamamoto T, Mimura S, Matsui A, Ohno A, Koh H, Saitoh E, Nagoshi S, Fujiwara K
- Journal Title
  
  Biochem Biophys Res Commun 317
  
  Pages: 114-120
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370191
[Journal Article] Extrahepatic manifestation in Transgenic Mice of Osteopontin in Hepatocytes : A Clue to Advent of Pathological State in Various Organs of Chronic Hepatitis C Patients
- Author(s)
  Saitoh E, Matsui A, Inao M, Mimura S, Koh H, Ohno A, Nagoshi S, Kayano H, Yoshimoto T, Mochida S, Fujiwara K
- Journal Title
  
  Hepatol Res (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370191
[Journal Article] SNPs in the Promoter Region of Osteopontin Gene as a Marker Predicting the Efficacy of Interferon-Based Therapies in Chronic Hepatitis C
- Author(s)
  Naito M, Matsui A, Inao M, Nagoshi S, Nagano M, Ito N, Egashira T, Hashimoto M, Mishiro S, Mochida S, Fujiwara K
- Journal Title
  
  J Gastroenterol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370191
[Journal Article] Increased Cytoprotective Function in the Liver of Transgenic Mice Expressing Osteopontin in Hepatocytes
- Author(s)
  Koh H, Matsui A, Mimura S, Inao M, Saitoh E, Ohno A, Nagoshi S, Yoshimoto T, Mochida S, Fujiwara K
- Journal Title
  
  Hepatol Res (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370191
[Patent] 感染による病変の程度を予測するためのデータを収集する方法2003
- Inventor(s)
  持田智, 藤原研司, 三代俊治, 他
- Industrial Property Rights Holder
  株式会社東芝
- Filing Date
  2003-09-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370191
[Patent] 感染による病変の程度を予測するためのデータを収集する方法2003
- Inventor(s)
  持田智, 藤原研司, 三代俊治, 他
- Industrial Property Rights Holder
  株式会社東芝
- Filing Date
  2003-09-24
- Data Source
  KAKENHI-PROJECT-14370191

1. MOCHIDA Satoshi (20219968)

# of Collaborated Projects: 7 results

# of Collaborated Products: 6 results
2. NAGOSHI Sumiko (50306271)

# of Collaborated Projects: 6 results

# of Collaborated Products: 6 results
3. INAO Mie (70286037)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
4. MATSUI Atsushi (40260484)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
5. OGATA Itsuo (80169169)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. TOMIYA Tomoaki (90227637)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. HIRATA Keiichi (50199064)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. OTA Shinichi (30185269)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. ARAI Shin (20306294)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. OKA Yuji (20160658)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. OHTA Yasuhiko (60124666)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. IKEDA Hitoshi (80202422)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. YAMANOBE Fumio (90286097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OKA Hiroshi (10010258)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 佐藤譲

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SATO Yuzuru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

FUJIWARA KENJI 藤原 研司

FUJIWARA Kenji 藤原 研司

Research Projects

Research Products

Co-Researchers

Genetic Polymorphisms in Promoter Regions of Osteopontin Gene as Host Factors to Determine Th1 Immune Reactions against Hepatitis Virus.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Study on Strategies for Non-Heart Beating LiverPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New devices in anticoagulant therapy for massive hepatic necrosis through sinusoidal fibrin depositionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Purification of hepatocyte comitogenic factor in plasma membrane and its action site (s) in hepatocyte proliferation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Factors Associated with Insufficient Liver Regeneration in Fulminant Hepatic FailurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ROLE OF SUPEROXIDE FROM MACROPHAGES IN HEPATIC FIBROSISPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

FUJIWARA KENJI 藤原研司

FUJIWARA Kenji 藤原研司