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KAWAZOE Yutaka  川添 豊

ORCIDConnect your ORCID iD *help
Researcher Number 80106252
External Links
Affiliation (based on the past Project Information) *help 1986 – 1996: 名古屋市立大学, 薬学部, 教授
Review Section/Research Field
Principal Investigator
Chemical pharmacy / Biological pharmacy / 医薬分子機能学
Except Principal Investigator
Chemical pharmacy
Keywords
Principal Investigator
リグニン / 合成リグニン / エイズ / 変異原性 / キノリン / 抗菌性 / 遺伝毒性 / 代謝 / 抗ウイルス剤 / Anti-HIV … More / lignins / quinoline / 制がん剤 / 静止期細胞 / 抗ウイルス活性 / BRM / 抗ウイルス性 / Quinolines / Microsomal enzyme / Metabolic activation / Fluorine derivative / Genotoxicity / Carcinogenicity / Heteroaromatics / Metabolism / 芳香族アミン / アミノキノリン / フッ素置換 / キノリン誘導体 / ミクロゾ-ム酵素 / 発癌活性化 / フッ素置換体 / 発癌性 / 含窒素複素環化合物 / AIDS / carcinogenicity / genotoxicity / mutagenicity / metabolism / lignin / nitrogen-containing aromatics / 発癌 / 含窒素芳香族化合物 / N-amino nucleic acid bases / antiviral activity / antitumor activity / alkylating agents / N-nitrosoureas / 抗がん剤 / N-アミノ化合物 / ニトロソ尿素 / N-ニトロソ尿素 / N-アミノ核酸塩基 / アルキル化剤 / N-ニトロン尿素 / antiviral / lignified materials / Anti-tumor promoter / bacterial infection / synthetic lignins / 木質化素材 / 細胞毒性物質 / 発癌プロモーター活性 / 感染予防 / 抗発癌プロモーター活性 / 抗 / 水質化素材 / pharmacology / AIDS treatment / 細胞毒性 / HIV / エイズ治療薬 / liver microsomal enzymes / detoxication / metabolic activation / enamine epoxide / ベイ領域エポキシド / エナミンエポキシド説 / 発がん性 / エナミンエポキシド仮説 / 肝ミクロゾーム酵素 / 解毒代謝 / 代謝活性化 / エナミンエポキシド仮設 / 固型がん / 一次スクリーニング / 抗腫瘍薬 / スクリーニング法 / 培養細胞 / 固型癌 / 制癌剤 / 免疫反応 / 日和見感染症 / マクロファ-ジ / 好中球 / 免疫賦活 / 木質化天然物 … More
Except Principal Investigator
アミノ化 / 鶏卵法 / ヒト固型腫瘍 / 合成制癌剤 / ダイデムニンB / Guanine / Guanosine / Deoxyguanosine / Amination / アリールヒドロキシルアミン / Nーアミノグアニン / N-アミノグアニン / グアニン / グアノシン / デオキシグアノシン / Physicochemical approach / Design of drugs / Macrolides / Sugars / Peptides / Structures / Efficient synthesis / Biologically active compounds / 効率的合成法 / 物理化学的アプロ-チ / 物理化学的アプローチ / 薬物創製 / マクロリド / 糖 / 生理活性ペプチド / 作用発現構造 / 効率的合成 / 生理活性物質 / 2'-メチリデンシチジン / 動物腫瘍 / ヌードマウス / 分化誘導活性 / 複素環化合物 / 新規合成制癌剤 / 8ーヒドロキシグアニン / serylーAMP / 4HAQO / 4NQO / 新規核酸関連化合物 / ミセル形成型白金錯体 / B16メラノーマ / ヒト前髓球性白血病細胞 / 分化誘導 / 受精鶏卵法 / 細胞分化誘導効果 / 3,5-ジ-t-ブチルカルコンカルボン酸 / ポルフイリンインターカレータ / 含フッ素アルキルスルホン酸 / N-アセチルノイラミン酸含有二糖変型ヌクレオシド / 2′-メチリデンシチジン類 / 大腸発がん / ホルボールエステル / フェルラ酸 / リグニン / 抗発がんイニシエーション / 抗発がんプロモーション / 発癌 / DNA修飾 / 核酸塩基 / DNA付加体 / 化学発癌 / 核酸 / 転移抑制物質の開発 / 形質転換細胞 / 転移腫瘍検出法 / PCR法 / 癌遺伝子 / 転移・浸潤 / ヒト腫瘍培養株 / トリフルオロ酢酸 / ジエチルリン酸シアニド / 立体選択的合成 / 海洋産ペプチド / 細胞毒性 / ドラスタチン10 / イソキノリン誘導体 / 5ーデアザフラビン誘導体 / 2'ーシアノシチジン / 制癌剤耐性 / 休止期細胞 / 癌転移抑制 / 抗腫瘍性 / ユリチアサイクラマイド / 立体配座 / 毒性発現機構 / 構造活性相関 / 制癌活性 / 合成 / 海洋産環状ペプチド / シコニン類 / 5ーデアザフラビン類 / シクロヘキサンジアミン白金錯体 / Cーキナーゼ / Aーキナーゼ / 蛋白リン酸化酵素 / エチルイミダゾールリボシド / 5ーフルオロー2'ーメチリデンシチジン Less
  • Research Projects

    (25 results)
  • Co-Researchers

    (26 People)
  •  静止期がん細胞を標的とした抗がん剤の一次スクリーニング法:固型がん治療薬の選別を目指してPrincipal Investigator

    • Principal Investigator
      川添 豊
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya City University
  •  Synthesis of N-thiocarbamoyl derivatives of N-amino nucleic acid bases and their antiviral activityPrincipal Investigator

    • Principal Investigator
      KAWAZOE Yutaka
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University
  •  高分子性リグニン類の発癌抑制作用の検討 -特に、消化器癌を標的として

    • Principal Investigator
      TAKAHASHI Kazuhiko
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya City University
  •  新しい視点からの一次スクリーニング法の確立を目指してPrincipal Investigator

    • Principal Investigator
      川添 豊
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya City University
  •  Diverse Biological Activities of Lignins : Structure-Activity RelationshipPrincipal Investigator

    • Principal Investigator
      KAWAZOE Yutaka
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      医薬分子機能学
    • Research Institution
      Nagoya City University
  •  制癌性BRMの新しいリード化合物を求めて一天然リグニンと関連ポリフェノールPrincipal Investigator

    • Principal Investigator
      川添 豊
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya City University
  •  核酸塩基の求電子的アミノ化反応:N-アミノ体を中間体とする新規修飾塩基類の合成

    • Principal Investigator
      幸田 光復
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya City University
  •  Pharmacological study on lignins as a class of anti-HIV agentsPrincipal Investigator

    • Principal Investigator
      KAWAZOE Yutaka
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Nagoya City University
  •  休止期細胞の動員と転移抑制効果を有する新合成制癌剤の探索

    • Principal Investigator
      佐々木 琢磨
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kanazawa University
  •  制癌性BRMの新しいリ-ド化合物を求めてー天然リグニンと関連ポリフェノ-ルPrincipal Investigator

    • Principal Investigator
      川添 豊
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya City University
  •  核酸塩基の求電子的アミノ化反応ーN.アミノ体を中間体とする新規修飾塩基類の合成

    • Principal Investigator
      幸田 光復
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya City University
  •  Mechanism of genotoxic quinoline derivatives : the Enamine Epoxide TheoryPrincipal Investigator

    • Principal Investigator
      KAWAZOE Yutaka
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Nagoya City University
  •  休止期細胞の動員と転移抑制効果を有する新合成制癌剤の探索

    • Principal Investigator
      佐々木 琢磨
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kanazawa University
  •  細胞毒性を有する海洋産環状ペプチドの合成と制癌への応用

    • Principal Investigator
      塩入 孝之
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya City University
  •  医薬品資源としての木質素材:リグニン分画の抗ウイルス活性と免疫賦活化能Principal Investigator

    • Principal Investigator
      川添 豊
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University
  •  Synthesis and Design of Structures of Biologically Active Compounds

    • Principal Investigator
      SHIOIRI Takayuki
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University
  •  休止期細胞の動員と転移抑制効果を有する新合成制癌剤の探索

    • Principal Investigator
      佐々木 琢磨
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kanazawa University
  •  生物活性を有する海洋産環状ペプチドの合成と制癌への応用

    • Principal Investigator
      SHIOIRI Takayuki
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya City University
  •  新しい合成制癌剤の開発

    • Principal Investigator
      佐々木 琢磨
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kanazawa University
  •  Metabolism of N-Containing Polycyclic Aromatic HydrocarbonsPrincipal Investigator

    • Principal Investigator
      KAWAZOE Yutaka
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Nagoya City University
  •  Deprivation of Genotoxicity of N-Containing Heteroaromatics: Effect of Fluorine SubstitutionPrincipal Investigator

    • Principal Investigator
      KAWAZOE Yutaka
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University
  •  4NQO処理細胞DNAにおける8ーヒドロキシグアニン残基の生成機構

    • Principal Investigator
      幸田 光復
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya City University
  •  Amination of nucleic acid bases-A basic study on the reaction mechanism of aminating carcinogens

    • Principal Investigator
      KOHDA Kohfuku
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Nagoya City University
  •  新しい合成制癌剤の開発

    • Principal Investigator
      佐々木 琢磨
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  新しい合成制癌剤の研究

    • Principal Investigator
      佐々木 琢磨
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kanazawa University
  • 1.  KOHDA Kohfuku (60124286)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 2.  KAIYA Toyo (10080201)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  TAKAHASHI Kazuhiko (40117833)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 4.  佐々木 琢磨 (90109976)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 5.  米田 文郎 (80040327)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 6.  兼松 顕 (70023041)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 7.  上田 亨 (00001032)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 8.  HAMADA Yasumasa (90117846)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  SHIOIRI Takayuki (20012627)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  首藤 紘一 (50012612)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  大場 義樹 (10012634)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  前田 満和 (60157146)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  坂上 宏 (50138484)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  YONEMITSU Osamu (60001038)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  IKEGAMI Shiro (10119555)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  ARATA Yoji (40011499)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  SUZUKI Hideo (50013321)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SAEKI Kenichi (60254306)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  宮本 謙一 (30100514)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  多田 万里子 (90073113)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  KONNO Kunio
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  GORROD John
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  YAGI Haruhiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  JERINA Donald
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  NONOYJAMA Me
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  NONOYAMA Meihan
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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