KOGA Nobuyuki 古賀信幸

Researcher Number	80136514
Other IDs
Affiliation (based on the past Project Information) *help	2012 – 2015: 中村学園大学, 栄養科学部, 教授 2013 – 2014: 中村学園大学, 公私立大学の部局等, 教授 2010: 中村学園大学, 栄養科学部, 教授 2002 – 2004: 中村学園大学, 栄養科学部, 教授 2000 – 2001: 中村学園大学, 家政学部, 教授 1995 – 1999: 中村学園大学, 家政学部, 助教授
Review Section/Research Field	Principal Investigator Environmental pharmacy Except Principal Investigator 家政学 / Biological pharmacy / Eating habits / Risk sciences of radiation/Chemicals / Chemistry related to living body
Keywords	Principal Investigator CB187 / CB118 / toxicological assessment / cytochrome P450 / 毒性評価 / チトクロムP450 / hydroxy-metabolite / 環境ホルモン / 胎児培養法 / 代謝物 … More / 代謝 / ダイオキシン類 / 胎児培養 / CB138 / flavin contaning monooxygenase / methylsulfone / polychlorinated biphenyl / メチルスルホン体 / フラビン含有モノオキシゲナーゼ / メチルスルホン / ポリ塩素化ビフェニル … More Except Principal Investigator 抗酸化活性 / 環境動態 / 海藻 / FOOD LIFE / RECEPTORS / PROTECTION OF ATHEROSCLEROSIS / LIPOPROTEIN HIGH DENSITY / 高密度リボ蛋白質 / 食生活 / レセプター / 動脈硬化予防 / 高密度リポ蛋白質 / enzyme inhibition / enzyme induction / cytochrome P450 / rat liver microsomes / epicatechins / caffeine / 酵素誘導と阻害 / シトクロムP-450 / ラット肝ミクロゾーム / 酵素阻害 / 酵素誘導 / シトクロムP450 / ラット肝ミクロソーム / カテキン類 / カフェイン / in vitro代謝 / 肝ミクロゾーム / heptamethosyflavone / HPLC / 脱メチル化 / in vivo代謝 / ラット / natsudaidain / ポリメトキシフラボノイド類 / heptamethoxyflavone / nobiletin / 生体内動態 / 熱安定性 / カラマンダリン果皮 / ポリメトキシフラボン類 / 内分泌かく乱性 / クジラ / 血清 / 臭素化合物 / ヒト / 代謝 / ハロゲン化ビピロール / methoxy PBDE / イタチザメ / 海洋哺乳動物 / 生産菌 / 培養 / hydroxy-PBDE / 海綿 / メチル化 / Hydroxy-PBDE / 生物濃縮 / 食物連鎖 / 天然臭素化合物 Less

Biotransformation of naturally occurring polymethoxyflavones and the effect of cooking processing on their anti-oxidative activity.
- Principal Investigator
  
  OHTA CHIHO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Nakamura Gakuen College
Metabolic activation of naturally porduced halogenated compounds in human
- Principal Investigator
  
  KOICHI Haraguchi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Daiichi University, College of Pharmaceutical Sciences
Formation and bioconcentration of natural organohalogen compounds in Asia-Pacific food web
- Principal Investigator
  
  HARAGUCHI Koichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Daiichi University, College of Pharmaceutical Sciences
Study on a new method for toxicological assessment of non-dioxin-tipe halogenated compoundsPrincipal Investigator
- Principal Investigator
  
  KOGA Nobuyuki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Nakamura Gakuen University
A mechanism on the formation of hightpersistant PCB metabolites, methylsulfonePCBs, and their toxicological assessimentPrincipal Investigator
- Principal Investigator
  
  KOGA Nobuyuki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Nakamura Gakuen University
NEW ASPECTS OF THE PROTECTIVES ON ATHEROSCLEROSIS BY FOODLIFE-REKATION WITH HDL-RECEPORS
- Principal Investigator
  
  HARA Takayuki
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  家政学
- Research Institution
  NAKAMURA GAKUEN UNUVERSITY
Search for food constituents having ability to induce or inhibit liver enzymes and their safety assessment
- Principal Investigator
  
  YOSHIMURA Hidetoshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nakamura Gakuen University

All 2016 2015 2014 2013 2011 2010 2008 2005 2004 2003 2002 Other

All Journal Article Presentation

[Journal Article] 黒ショウガ成分5,7,3',4'-Tetramethoxyflavoneのラット肝ミクロゾームによる代謝．2016
- Author(s)
  太田千穂、緒方　瞳、山本健太、原口浩一、加藤善久、遠藤哲也、古賀信幸
- Journal Title
  
  中村学園大学・中村学園短期大学部研究紀要
  
  Volume: 48 Pages: 155-161
- NAID
  120005850758
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25350115
[Journal Article] Distribution and excretion of 2,2',3,4',5,5'-heptachlorobiphenyl (CB187) and its metabolites in rats and guinea pigs.2015
- Author(s)
  Ohta C, Haraguchi K, Kato Y, Endo T, Kimura O, Koga N。
- Journal Title
  
  Chemosphere
  
  Volume: 118 Pages: 5-11
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25350115
[Journal Article] Distribution and excretion of　2,2′,3,4′,5,5′,6-heptachlorobiphenyl (CB187) and its metabolites in rats and guinea pigs.2015
- Author(s)
  Ohta, C.; Haraguchi, K.; Kato, Y.; Endo, T.; Kimura, O.; Koga, N.
- Journal Title
  
  Chemosphere
  
  Volume: 118 Pages: 5-11
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24310049
[Journal Article] Carrier-mediated uptake of nobiletin, a citrus polymethoxyflavonoid, in human intestinal Caco-2 cells.2014
- Author(s)
  Kimura O, Ohta C, Koga N, Haraguchi K, Kato Y, Endo T.
- Journal Title
  
  Food Chemistry
  
  Volume: 154 Pages: 145-150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25350115
[Journal Article] 3,3′,4,4′-Tetrachlorobiphenyl-Mediated Decrease of Serum Thyroxine Level in C57BL/6 and DBA/2 Mice Occurs Mainly through Enhanced Accumulation of Thyroxine in the Liver2014
- Author(s)
  Yoshihisa Kato, Koichi Haraguchi, Mao Onishi, Shinichi Ikushiro, Tetsuya Endo, Chiho Ohta, Nobuyuki Koga, Shizuo Yamada, and Masakuni Degawa
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 37 Issue: 3 Pages: 504-509
- DOI
  10.1248/bpb.b13-00775
- NAID
  130003382126
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23510083, KAKENHI-PROJECT-24310049, KAKENHI-PROJECT-26340043
[Journal Article] Uptake of Aristolochic Acid I into Caco-2 Cells by Monocarboxylic Acid Transporters2014
- Author(s)
  Osamu Kimura, Koichi Haraguchi, Chiho Ohta, Nobuyuki Koga, Yoshihisa Kato, Tetsuya Endo
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 37 Issue: 9 Pages: 1475-1479
- DOI
  10.1248/bpb.b14-00219
- NAID
  130004684786
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510083, KAKENHI-PROJECT-24310049, KAKENHI-PROJECT-25303011, KAKENHI-PROJECT-26340043
[Journal Article] Uptake of aristolochic acid Ⅰinto caco-2 cells by monocarboxylic acid transporters.2014
- Author(s)
  Kimura O, Haraguchi K, Ohta C, Koga N, Kato Y, Endo T.
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 37（9） Pages: 1-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25350115
[Journal Article] ラットおよびモルモットの腎および小腸におけるノビレチンの代謝2013
- Author(s)
  太田千穂、加藤善久、原口浩一、遠藤哲也、古賀信幸
- Journal Title
  
  中村学園大学・短期大学部研究紀要
  
  Volume: 45 Pages: 141-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25350115
[Journal Article] Levels of Mercury in Muscle and Liver of Star-Spotted Dogfish (Mustelus manazo) from the Northern Region of Japan: A Comparison with Spiny Dogfish (Squalus acanthias).2013
- Author(s)
  Tetsuya Endo
- Journal Title
  
  Arch. Environ. Contam. Toxicol.
  
  Volume: 64 Issue: 3 Pages: 467-474
- DOI
  10.1007/s00244-012-9858-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510083, KAKENHI-PROJECT-24310049, KAKENHI-PROJECT-25303011
[Journal Article] Detection of adulterated Shikuwasha juice by sensory evalution, colorimetric value and volatile components.2013
- Author(s)
  Yamamoto K, Yahada A, Sasaki K, Funakoshi-Yoshida A, Ohta C, Koga N, Ohta H.
- Journal Title
  
  Food Science and Technology Research
  
  Volume: 19(5) Pages: 843-848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25350115
[Journal Article] A possible mechanism for 2,3',4,4',5'-pentachlorobiphenyl-mediated decrease in serum thyroxine level in mice.2013
- Author(s)
  Kato, Y., Onishi, M., Haraguchi, K., Ikushiro, S., Ohta, C., Koga, N., Endo, T., Yamada, S., Degawa, M.
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 36 Pages: 1594-1601
- NAID
  130003361538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310049
[Journal Article] Marine sponge : A potential source for methoxylated polybromiated diphenyl ethers in the Asia-Pacific food web2011
- Author(s)
  Haraguchi K, Kato Y, Ohta C, Koga N, Endo T.
- Journal Title
  
  J. Agric. Food Chem
  
  Volume: 59 Pages: 13102-13109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20404006
[Journal Article] Species differences in tissue distribution of catechol and methylsulphonyl metabolites of polychlorinated biphenyls in rats, mice, hamsters and guinea pigs.2005
- Author(s)
  K.Haraguchi, Y.Kato, N.Koga, M.Degawa
- Journal Title
  
  Xenobiotica (in press)
- Data Source
  KAKENHI-PROJECT-14572119
[Journal Article] Species differences in tissue distribution of catechol and methylsulphonyl metabolites of polychlorinated biphenyls in rats, mice, hamsters, and guinea pigs.2005
- Author(s)
  K.Haraguchi, Y.Kato, N.Koga, M.Degawa
- Journal Title
  
  Xenobiotica. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572119
[Journal Article] Comparative metabolism of polychlorinated biphenyls and tissue distribution of persistent metabolites in rats, hamsters and guinea pigs.2005
- Author(s)
  K.Haraguchi, N.Koga, Y.Kato
- Journal Title
  
  Drug Metab.Dispos. 33
  
  Pages: 373-380
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572119
[Journal Article] In vitro metabolism of 2,2',3,4'5,5',6-heptachlorobiphenyl (CB187) by liver microsoms from rats, hamsters and guinea pigs.2005
- Author(s)
  C.Ohta, K.Haraguchi, Y.Kate, N.Koga
- Journal Title
  
  Xenobiotica. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572119
[Journal Article] In vitro metabolism of 2,2',3,4',5,5',6-heptachlorobilphenyl (CB187) with liver microsomes from rats, hamsters and guinea pigs.2005
- Author(s)
  C.Ohta, K.Haraguchi, Y.Kato, N.Koga
- Journal Title
  
  Xenobiotica (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572119
[Journal Article] Metabolism of polychlorinated biphenyls by Gunn rats : Identification and serun retention of catechol metabolites.2004
- Author(s)
  K.Haraguchi, Y.Kato, N.Koga, M.Degawa
- Journal Title
  
  Chem.Res.Toxicol. 17
  
  Pages: 1684-1691
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572119
[Journal Article] Reduction of the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice using an antiulcer drug geranylgeranylacetone.2004
- Author(s)
  T.Ishida, T.Oshimo, A.Nishimura, J.Mutoh, Y.Ishii, N.Koga, H.Yamada, I.Hashiguchi, A.Akamine, K.Oguri
- Journal Title
  
  Biol.Pharm.Bull. 27
  
  Pages: 1397-1402
- NAID
  110003608983
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572119
[Journal Article] In vitro metabolism of 2,2',3,4',5,5',6-heptachlorobiphenyl (CB187) with liver microsomes from rats, hamsters and guinea pigs.2004
- Author(s)
  N.Koga, C.Ohta, K.Haraguchi, T.Kanamaru, Y.Kato, S.Yamada
- Journal Title
  
  Organohalogen Compounds 66
  
  Pages: 2923-2927
- Data Source
  KAKENHI-PROJECT-14572119
[Journal Article] Metabolism of polychlorinated biphenyls by Gunn rats : Identification and serum retention of catechol metabolites.2004
- Author(s)
  K.Haraguchi, Y.Kato, N.Koga, M.Degawa
- Journal Title
  
  Chem.Res.Toxicol. 17(12)
  
  Pages: 1684-1691
- Data Source
  KAKENHI-PROJECT-14572119
[Journal Article] Comparative metabolism of polychlorinated biphenyls and tissue distribution of persistent metabolites in rats, hamsters and guinea pigs.2004
- Author(s)
  K.Haraguchi, N.Koga, Y.Kato
- Journal Title
  
  Drug Metab.Dispos. (in press)
- Data Source
  KAKENHI-PROJECT-14572119
[Journal Article] Reduction of the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice using an antiulcer drug, geranylgeranylacetone.2004
- Author(s)
  T.Ishida, T.Oshimo, A.Nishimura, J.Mutoh, Y.Ishii, N.Koga, H.Yamada, I.Hashiguchi, A.Akamine, K.Oguri
- Journal Title
  
  Biol.Pharm.Bull. 27
  
  Pages: 1397-1402
- NAID
  110003608983
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572119
[Journal Article] Metabolism of polychlorinated biphenyls by Gunn rats : Identification and serum retention of catechol metabolites.2004
- Author(s)
  K.Haraguchi, Y.Kato, N.Koga, M.Degawa
- Journal Title
  
  Chem Res.Toxicol. 17
  
  Pages: 1684-1691
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572119
[Journal Article] Effects of Polychlorinated Biphenyls, Kanechlor-500, on Serum Thyroid Hormone Level in Rats and Mice.2003
- Author(s)
  Y.Kato, K.Haraguchi, T.Yamazaki, Y.Ito, S.Miyajima, K.Nemoto, N.Koga, R.Kimura, M.Degawa
- Journal Title
  
  Toxicol.Sci. 72
  
  Pages: 235-241
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572119
[Journal Article] 2,3,3',4,4'-五塩素化ビフェニール(CB105)のハムスターにおける代謝2003
- Author(s)
  古賀信幸, 原口浩一, 金丸知代, 加藤善久, 木村良平
- Journal Title
  
  福岡医誌 94
  
  Pages: 174-182
- NAID
  120002662608
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572119
[Journal Article] Effects of polychlorinated biphenyls, Kanechlor-500 on serum thyroid hormone levels in rats and mice.2003
- Author(s)
  Y.Kato, K.Haraguchi, T.Yamazahi, Y.Ito, S.Miyajima, K.Nemoto, N.Koga, R.Kimura, M.Degawa
- Journal Title
  
  Toxicol.Sci. 72
  
  Pages: 235-241
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572119
[Journal Article] Metabolism of 2,3,3',4,4'-pentachlorobiphenyl (CB105) in hamsters (in Japanese).2003
- Author(s)
  N.Koga, T.Kanamaru, H.Kuroki, K.Haraguchi, Y.Kato, R.Kimura
- Journal Title
  
  Fukuoka Acta Med. 94
  
  Pages: 174-182
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572119
[Journal Article] A metabolite of 2,2',4',5-tetrabromobiphenyl, 3-methlylsulfonyl-2,2',4',5-tetrabromobiphenyl, is a poent inducer of CYP2B1/2 in the rat.2002
- Author(s)
  Y.Kato, K.Haraguchi, S.Yumoto, T.Yamazaki, Y.Nagano, N.Koga, Y.Masuda, R.Kimura
- Journal Title
  
  Xenobiotica 32
  
  Pages: 289-303
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572119
[Journal Article] A metabolite of 2,2',4',5-tetrabromobiphenyl, 3-methylsulfonyl-2,2',4',5-tetrabromobiphenyl, is a potent inducer of CYP2B1/2 in the rat.2002
- Author(s)
  Y.Kato, K.Haraguchi, S.Yumoto, T.Yamazaki, Y.Nagano, N.Koga, Y.Masuda, R.Kimura
- Journal Title
  
  Xenobiotica. 32
  
  Pages: 289-303
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572119
[Presentation] Caco-2細胞におけるアリストロキア酸Iの膜透過に及ぼすケルセチンの影響2016
- Author(s)
  ①木村　治，藤井由希子，原口浩一，太田千穂，古賀信幸，加藤善久，遠藤哲也．
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜・パシフィコ横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-25350115
[Presentation] 黒ショウガ成分3,5,7,4'-Tetramethoxyflavoneの動物肝ミクロゾームおよびヒトチトクロムP450による代謝2015
- Author(s)
  山本健太，太田千穂，原口浩一，遠藤哲也，加藤善久，古賀信幸
- Organizer
  平成27年度（公社）日本栄養・食糧学会九州・沖縄支部および（公社）日本食品科学工学会西日本支部合同大会
- Place of Presentation
  沖縄・ネストホテル那覇
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-25350115
[Presentation] In vitro metabolism of nobiletin in the small intestine and kidney of rats and guinea pigs.2015
- Author(s)
  Ohta C, Kato Y, Haraguchi K, Endo T, Koga N
- Organizer
  12th Asian Congress of Nutrition
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2015-05-14
- Data Source
  KAKENHI-PROJECT-25350115
[Presentation] In vitro metabolism of kaempherol tetramethylether by rat liver microsomes.2015
- Author(s)
  Yamamoto K, Ohta C, Ogata H, Endo T, Kimura O, Kato Y, Haraguchi K, Koga N
- Organizer
  12th Asian Congress of Nutrition
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2015-05-14
- Data Source
  KAKENHI-PROJECT-25350115
[Presentation] Caco-2細胞におけるアリストロキア酸の細胞内取込み機構2014
- Author(s)
  遠藤哲也，木村　治，原口浩一，太田千穂，古賀信幸，加藤善久
- Organizer
  第134年会日本薬学会
- Place of Presentation
  熊本市総合体育館・熊本大学、熊本市
- Data Source
  KAKENHI-PROJECT-25350115
[Presentation] Kaempferol tetramethyletherのラット肝ミクロゾームによる代謝2014
- Author(s)
  山本健太，緒方　瞳，太田千穂，原口浩一，遠藤哲也，木村　治，加藤善久，古賀信幸
- Organizer
  第68回日本栄養・食糧学会大会
- Place of Presentation
  酪農学園大学、札幌・北海道
- Data Source
  KAKENHI-PROJECT-25350115
[Presentation] In vitro metabolism of 2,2’,4,4’,5-pentachlorobiphenyl (CB99) by rat and guinea pig liver microsomes2013
- Author(s)
  Ohta C, Haraguchi K, Kato Y, Endo T, Kimura O, Koga N.
- Organizer
  33rd International Symposium on Halogenated Persistent Organic Pollutants and POPs
- Place of Presentation
  Daegu, Korea
- Data Source
  KAKENHI-PROJECT-24310049
[Presentation] テトラメトキシフラボノイド類のラット肝ミクロゾームによる代謝2013
- Author(s)
  緒方　瞳，太田千穂，山本健太，加藤善久，原口浩一，古賀信幸
- Organizer
  平成25年度日本栄養・食糧学会九州・沖縄支部および日本食品科学工学会西日本支部合同大会
- Place of Presentation
  九州大学農学部、福岡市
- Data Source
  KAKENHI-PROJECT-25350115
[Presentation] In vitro metabolism of 3,5,6,7,8,3',4'-heptamethoxyflavone by rat liver microsomes.2013
- Author(s)
  Koga N, Matsuoka M, Ohta C, Kato Y, Haraguchi K Kimura O, Endo T,
- Organizer
  20th International Congress of Nutrition (ICN 2013)
- Place of Presentation
  The Granada Congress Center, Granada, Spain
- Data Source
  KAKENHI-PROJECT-25350115
[Presentation] In vitro metabolism of diosmetin and hesperetin by rat liver microsomes.2013
- Author(s)
  Ohta C, Kato Y, Haraguchi K, Koga N.
- Organizer
  20th International Congress of Nutrition (ICN 2013)
- Place of Presentation
  The Granada Congress Center, Granada, Spain
- Data Source
  KAKENHI-PROJECT-25350115
[Presentation] 海洋生物由来2,2’-dimethoxy-BB80のラット肝ミクロゾームによる代謝と抗酸化活性2013
- Author(s)
  西村恵理、太田千穂、原口浩一、遠藤哲也、加藤善久、古賀信幸
- Organizer
  フォーラム2013, 衛生薬学・環境トキシコロジー学会
- Place of Presentation
  九州大学（福岡市東区）
- Data Source
  KAKENHI-PROJECT-24310049
[Presentation] A potential source for hydroxylated and methyoxylated analogs of brominated diphenyl ethers in the Asia-Pacific food web2011
- Author(s)
  Haraguchi K, Kato Y, Ohta C, Koga N, Endo T.
- Organizer
  31^<th> Intern Symposium on Halogenated Persistent Organic Pollutants(POPs)
- Place of Presentation
  Brussels, Belgium, Organohalogen Compounds
- Data Source
  KAKENHI-PROJECT-20404006
[Presentation] 新規PBDE関連物質の鯨類組織分布および地域差2010
- Author(s)
  原口浩一, 伊藤美子, 太田千穂, 古賀信幸, 遠藤哲也
- Organizer
  フォーラム2010・衛生環境トキシコロジー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20404006
[Presentation] 海洋哺乳動物におけるPCB代謝:鯨類の肝臓にみられるmethylsulfoneおよびdihydroxy体の蓄積特性2008
- Author(s)
  原口浩一、久道洋輔、遠藤哲也、加藤善久、太田千穂、古賀信幸
- Organizer
  フォーラム2008 :衛生薬学・環境トキシコロジー
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-20404006
[Presentation] GC/MS-EI/SIMによる天然ハロゲン化合物の定量:サメにおける蓄積特性2008
- Author(s)
  久道洋輔、遠藤哲也、加藤善久、太田千穂、古賀信幸、原口浩一
- Organizer
  フォーラム2008 :衛生薬学・環境トキシコロジー
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-20404006
[Presentation] In vitro metabolism of nobiletin in the small intestine and kidney of rats and guinea pigs.
- Author(s)
  Ohta C, Kato Y, Haraguchi K, Endo T, Koga N.
- Organizer
  12th Asian Congress of Nutrition
- Place of Presentation
  Yokohama、Japan
- Year and Date
  2015-05-14 – 2015-05-18
- Data Source
  KAKENHI-PROJECT-25350115
[Presentation] 海洋生物由来のTetrabromo-1,4-dimethoxybenzene(TDB)の動物肝ミクロゾームによる代謝
- Author(s)
  太田千穂、西村理恵、原口浩一、遠藤哲也、加藤善久、山元健太、古賀信幸
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24310049
[Presentation] トリメチル化apigeninおよびgenisteinのラット肝ミクロゾームによる代謝
- Author(s)
  緒方　瞳、太田千穂、山本健太、原口浩一、遠藤哲也、木村　治、加藤善久、古賀信幸
- Organizer
  平成26年度日本栄養・食糧学会九州・沖縄支部大会
- Place of Presentation
  熊本県立大学、熊本県
- Year and Date
  2014-10-11 – 2014-10-12
- Data Source
  KAKENHI-PROJECT-25350115
[Presentation] 海洋生物由来のtetrabromoveratrole(TBV)の動物肝ミクロゾームによる代謝
- Author(s)
  太田千穂、西村恵理、原口浩一、遠藤哲也、加藤善久、山本健太、古賀信幸
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本市中央区）
- Data Source
  KAKENHI-PROJECT-24310049
[Presentation] メチルトリクロサンのマウス代謝活性化と乳汁分泌
- Author(s)
  久我歩佳、木下真璃伽、藤井由希子、櫻田司、原口浩一、太田千穂、古賀信幸、遠藤哲也
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24310049
[Presentation] 海洋生物由来のTetrabromo-1,4-dimethoxybenzen (TDB)の動物肝ミクロゾームによる代謝
- Author(s)
  太田千穂、西村恵理、原口浩一、遠藤哲也、加藤善久、山本健太、古賀信幸
- Organizer
  第135年会日本薬学会
- Place of Presentation
  神戸サンボーホール、兵庫県
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25350115
[Presentation] 海洋生物由来2,2’-dimethoxy-BB80のラットにおけるin vivo代謝
- Author(s)
  西村恵理、太田千穂、原口浩一、遠藤哲也、加藤善久、山本健太、古賀信幸
- Organizer
  フォーラム2014衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-24310049
[Presentation] Kaempherol tetramethyletherのラット肝ミクロゾームによる代謝
- Author(s)
  山本健太、緒方　瞳、太田千穂、原口浩一、遠藤哲也、木村　治、加藤善久、古賀信幸
- Organizer
  第68回日本栄養・食糧学会大会
- Place of Presentation
  酪農学園大学、札幌・北海道
- Year and Date
  2014-05-30 – 2014-06-01
- Data Source
  KAKENHI-PROJECT-25350115
[Presentation] 海洋生物由来2,2'-dimethoxy-BB80のラットにおけるin vivo代謝
- Author(s)
  西村恵理、太田千穂、原口浩一、遠藤哲也、加藤善久、山本健太、古賀信幸
- Organizer
  フォーラム2014：衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば国際会議場、茨木県
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-25350115

1. HARAGUCHI Koichi (00258500)

# of Collaborated Projects: 4 results

# of Collaborated Products: 29 results
2. OHTA Chiho (80271435)

# of Collaborated Projects: 3 results

# of Collaborated Products: 33 results
3. ENDO Tetsuya (10133216)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
4. KANAMARU Tomoyo (50291836)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. KOTAKI Yuichi (30113278)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MATSUBARA Futoshi (60368975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KATO Yoshihisa (90161132)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. YAMAMOTO Kenta (50709582)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
9. YOSHIMURA Hidetoshi (00037566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KATO Sachiko (70069780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HARA Takayuki (10164998)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KUROKI Hiroaki (60258499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. AKITA Masaharu (30231822)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 柳瀬敏彦 (30239818)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. OGATA Hitomi

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
16. OHISHI Nahoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KOGA Nobuyuki 古賀 信幸

Research Projects

Research Products

Co-Researchers

Biotransformation of naturally occurring polymethoxyflavones and the effect of cooking processing on their anti-oxidative activity.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Metabolic activation of naturally porduced halogenated compounds in human

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Formation and bioconcentration of natural organohalogen compounds in Asia-Pacific food web

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on a new method for toxicological assessment of non-dioxin-tipe halogenated compoundsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A mechanism on the formation of hightpersistant PCB metabolites, methylsulfonePCBs, and their toxicological assessimentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

NEW ASPECTS OF THE PROTECTIVES ON ATHEROSCLEROSIS BY FOODLIFE-REKATION WITH HDL-RECEPORS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search for food constituents having ability to induce or inhibit liver enzymes and their safety assessment

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 黒ショウガ成分5,7,3',4'-Tetramethoxyflavoneのラット肝ミクロゾームによる代謝．2016

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Distribution and excretion of 2,2',3,4',5,5'-heptachlorobiphenyl (CB187) and its metabolites in rats and guinea pigs.2015

Author(s)

Journal Title

Data Source

[Journal Article] Distribution and excretion of 2,2′,3,4′,5,5′,6-heptachlorobiphenyl (CB187) and its metabolites in rats and guinea pigs.2015

Author(s)

Journal Title

Data Source

[Journal Article] Carrier-mediated uptake of nobiletin, a citrus polymethoxyflavonoid, in human intestinal Caco-2 cells.2014

Author(s)

Journal Title

Data Source

[Journal Article] 3,3′,4,4′-Tetrachlorobiphenyl-Mediated Decrease of Serum Thyroxine Level in C57BL/6 and DBA/2 Mice Occurs Mainly through Enhanced Accumulation of Thyroxine in the Liver2014

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Uptake of Aristolochic Acid I into Caco-2 Cells by Monocarboxylic Acid Transporters2014

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Uptake of aristolochic acid Ⅰinto caco-2 cells by monocarboxylic acid transporters.2014

KOGA Nobuyuki 古賀信幸

[Journal Article] Distribution and excretion of　2,2′,3,4′,5,5′,6-heptachlorobiphenyl (CB187) and its metabolites in rats and guinea pigs.2015