SHIBATA Osamu 柴田治

… Alternative Names

柴田治シバタオサム

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Researcher Number	80136671
Other IDs
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Affiliation (based on the past Project Information) *help	2009: Nagasaki University, 病院, 准教授 2007 – 2008: Nagasaki University, 医学部・歯学部附属病院, 准教授 2003 – 2005: 長崎大学, 医学部・歯学部附属病院, 助教授 2002: 長崎大学, 医学部附属病院, 助教授 1997 – 2001: NAGASAKI UNIVERSITY,School of Medicine Hospital, Assistant Professor, 医学部・附属病院, 助教授 … More 1996 – 1997: Nagasaki University, Medicine, Hospital, Assistant Professor, 医学部附属病院, 助教授 1995 – 1996: 長崎大学, 医学部, 助教授 1986: 長崎大, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / 麻酔学 Except Principal Investigator Anesthesiology/Resuscitation studies
Keywords	Principal Investigator 気道平滑筋 / ラット / カテコラミン / イノシトールリン脂質代謝 / ファスジル / Rhoキナーゼ阻害薬 / small intestine / liver / dopamine / catecholamine … More / カテコールアミン / 抱合型 / 遊離型 / 消化管組織 / ドパミン負荷 / 胆汁 / 尿 / 血漿 / 腎 / 消化菅 / 肝臓 / ドーパミン / Rat / Muscarinic M3 receptor / Phosphatidylinositol / Rho-kinase / Anticholinesterases / Y-27632 / 抗コリンエステラーゼ / コリンエステラーゼ / Phosphatidylinositol response / Inositol monophosphate / Intravenous anesthetics / Spinal cord / 気管平滑筋 / クロニジン / イノシトールソン脂質 / 麻酔薬 / イノシトールリン脂質 / ノルアドレナリン / 脊髄 / potassium channel opener / airway smooth muscle / phosphatidylinositol / イノシトールリン脂 / Kチャネル / Kチャネル開口薬 / PIレスポンス / ベータ遮断薬 / アスジル / 連続性フィールド電気刺激 / Rhoキナーゼ / β遮断薬 … More Except Principal Investigator ERK / JNK / SAPK / ノルエピネフリン / isoflurane / Ischemia-Reperfusion / p38 MAPK / 腎機能障害 / 麻酔薬 / 薬理学的プレコンディショニング / イソフルラン / 虚血-再灌流障害 / p38MAPK / rat / cerebral cortex / norepinephrine / intravenous anesthetics / volatile anesthetics / phosphatidylinositol turnover / セボフルレン / イソフルレン / ハロセン / ラット / 大脳皮質 / ノルエピネクリン / 静脈麻酔薬 / 揮発性麻酔薬 / イノシトール燐脂質代謝回転 / 受容体サブタイプ / クロニジン / イノシトール-燐酸 / PI代謝回転 / αアドレナリン受容体 / 血管平滑筋 Less

Mechanisms of contraction/relaxation of airway smooth muscle : relationship between β-antagonist and Rho-kinase pathwayPrincipal Investigator
- Principal Investigator
  
  SHIBATA Osamu
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Nagasaki University
Mechanisms of airway smooth muscle contraction : physio-pharmacologic factors and intracellular signaling pathwayPrincipal Investigator
- Principal Investigator
  
  SHIBATA Osamu
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Nagasaki University Hospital of Medicine and Dentistry
Pharmacological preconditioning effect of isoflurane against renal ischemia/reperfusion injury in rats.
- Principal Investigator
  
  MOROOKA Hiroaki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Nagasaki University
血管平滑筋収縮におけるαアドレナリン受容体サブタイプと細胞内情報伝達機構の役割
- Principal Investigator
  
  IWANAGA Shu
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Nagasaki University
Effects of Intravenous anesthetics on Phosphatidylinositol Response of Spinal Descending Inhibitory Pathways of RatPrincipal Investigator
- Principal Investigator
  
  SHIBATA Osamu
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Nagasaki University
ROLES OF PHOSPHATIDYLINOSITOL IN THE MECHANISMS INVOLVED IN THE AIRWAY SMOOTH MUSCLE RELAXATION INDUCED BY ATP-SENSITIVE POTASSIUM CHANNEL OPENERSPrincipal Investigator
- Principal Investigator
  
  SHIBATA Osamu
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  NAGASAKI UNIVERSITY
Effects of Volatile Anesthetics on Phosphatidylinositol Turnover in Rat Cerebral Cortex.
- Principal Investigator
  
  TODOROKI Sachiko
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  NAGASAKI UNIVERSITY
Importance of Digestive Tract in Inactivation of CatecholaminesPrincipal Investigator
- Principal Investigator
  
  SHIBATA Osamu, 柴田治
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  麻酔学
- Research Institution
  Nagasaki University School of Medicine

All 2009 2008 2006 2004

All Journal Article Presentation

[Journal Article] Effects of amitriptyline, a tricyclic antidepressant, on smooth muscle reactivity in isolated rat trachea2009
- Author(s)
  Matsunaga S, Shibata O, Nishioka K, Tsuda A, Makita T, Sumikawa K
- Journal Title
  
  J Anesth 23(3)
  
  Pages: 385-91
- NAID
  10027264183
- Data Source
  KAKENHI-PROJECT-19591804
[Journal Article] Hyperosmolarity attenuates the contraction of rat trachea hrough the inhibition of phosphatidylinositol response2008
- Author(s)
  Saito M, Shibata O, Tsuda A, Makita T, Sumikawa K
- Journal Title
  
  ActaMedicaNagasakiensia 52
  
  Pages: 107-110
- Data Source
  KAKENHI-PROJECT-19591804
[Journal Article] High concentrations of landiolol, a beta(1)-adrenoceptor antagonist, stimulate smooth muscle contraction of the rat trachea through the Rho-kinase pathway2008
- Author(s)
  Shibata O, Nishioka K, Yamaguchi M, Makita T, Sumikawa K
- Journal Title
  
  J Anesth 22(1)
  
  Pages: 21-6
- NAID
  10024128507
- Data Source
  KAKENHI-PROJECT-19591804
[Journal Article] High concentrations of landiolol, a β1-adrenoceptor antagonist, stimulates smooth muscle contraction of the rat trachea through the Rho-kinase pathway2008
- Author(s)
  Osamu Shibata
- Journal Title
  
  J Anesth 22
  
  Pages: 21-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591804
[Journal Article] Anticholinesterase drugs stimulate smooth muscle contraction of the rat trachea through the Rho-kinase pathway.2006
- Author(s)
  Shibata O, Saito M, Yoshimura M, Yamaguchi M, Nishioka K, Makita T, Sumikawa K.
- Journal Title
  
  Anesth Analg. 102
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591638
[Journal Article] Anticholine sterase dmgs stimulate smooth muscle contraction of the rat trachea through the Rho-kinase pathway2006
- Author(s)
  Shibata O
- Journal Title
  
  Anesth Analg (in press)
- Data Source
  KAKENHI-PROJECT-15591638
[Journal Article] Propofol attenuates ovalbumin-induced smooth muscle contraction of the sensitized rat trachea; inhibition of serotonergic and cholinergic signaling.2006
- Author(s)
  Yamaguchi M, Shibata O, Nishioka K, Makita T, Sumikawa K.
- Journal Title
  
  Anesth Analg. (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591638
[Journal Article] Metoclopramide causes airway smooth muscle relaxation through inhibition of muscarinic M3 receptor in the rat trachea.2004
- Author(s)
  Saito M, Shibata O, Yamaguchi M, Yoshimura M, Makita T, Niwa M, Sumikawa K.
- Journal Title
  
  Anesth Analg. 98
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591638
[Journal Article] Selegiline, an MAO-B inhibitor, attenuates airway smooth muscle contraction in the rat trachea2004
- Author(s)
  Yoshimura M, Shibata O, Saito M, Yamaguchi M, Nishioka K, Makita T, Sumikawa K.
- Journal Title
  
  J Pharm Pharmacol. 56
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591638
[Presentation] ラット気管平滑筋における連続性フィールド電気刺激誘発性収縮に対するセボフルレンおよびRhoキナーゼ阻害薬ファスジルの影響2009
- Author(s)
  柴田治
- Organizer
  第56日本麻酔科学会
- Place of Presentation
  神戸
- Year and Date
  2009-08-17
- Data Source
  KAKENHI-PROJECT-19591804
[Presentation] Fasudil, a Rho-kinase inhibitor, potentiates the relaxant effect of sevoflurane on continuous electrical field stimulation-induced smooth muscle contraction of rat trachea2009
- Author(s)
  O. Shibata, S. Matsunaga, A. Tsuda, T. Makita, K. Sumikawa
- Organizer
  Eur J Anaesthesiol
- Data Source
  KAKENHI-PROJECT-19591804
[Presentation] ラット気管平滑筋における連続性フィールド電気刺激誘発性収縮に対するセボフルレンおよびRhoキナーゼ阻害薬ファスジルの影響2009
- Author(s)
  柴田治、松永祥志、津田敦、槙田徹次、澄川耕二
- Organizer
  日本麻酔科学会56
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19591804
[Presentation] ラット気管平滑筋におけるElectrical field stimulation誘発性収縮に対するRhoキナーゼ阻害薬フアスジルの影響2008
- Author(s)
  柴田治
- Organizer
  日本麻酔科学会第5 5回学術集会
- Place of Presentation
  横浜
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-19591804
[Presentation] ラット気管平滑筋におけるElectrical field stimulation誘発性収縮に対するRhoキナーゼ阻害薬ファスジルの影響2008
- Author(s)
  柴田治、松永祥志、津田敦、槙田徹次、澄川耕二
- Organizer
  日本麻酔科学会55
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19591804

1. SHIBATA Osamu (10180994)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. IWANAGA Shu (80274661)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. TODOROKI Sachiko (50039541)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MOROOKA Hiroaki (70230175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MAKITA Tetsuji (00229337)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. YAMAGUCHI Masakazu (80363498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 橋本茂 (70295062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 三好由紀子 (00174227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIBATA Osamu 柴田 治

柴田 治 シバタ オサム

Research Projects

Research Products

Co-Researchers

Mechanisms of contraction/relaxation of airway smooth muscle : relationship between β-antagonist and Rho-kinase pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of airway smooth muscle contraction : physio-pharmacologic factors and intracellular signaling pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pharmacological preconditioning effect of isoflurane against renal ischemia/reperfusion injury in rats.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

血管平滑筋収縮におけるαアドレナリン受容体サブタイプと細胞内情報伝達機構の役割

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of Intravenous anesthetics on Phosphatidylinositol Response of Spinal Descending Inhibitory Pathways of RatPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ROLES OF PHOSPHATIDYLINOSITOL IN THE MECHANISMS INVOLVED IN THE AIRWAY SMOOTH MUSCLE RELAXATION INDUCED BY ATP-SENSITIVE POTASSIUM CHANNEL OPENERSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of Volatile Anesthetics on Phosphatidylinositol Turnover in Rat Cerebral Cortex.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Importance of Digestive Tract in Inactivation of CatecholaminesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Effects of amitriptyline, a tricyclic antidepressant, on smooth muscle reactivity in isolated rat trachea2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Hyperosmolarity attenuates the contraction of rat trachea hrough the inhibition of phosphatidylinositol response2008

Author(s)

Journal Title

Data Source

[Journal Article] High concentrations of landiolol, a beta(1)-adrenoceptor antagonist, stimulate smooth muscle contraction of the rat trachea through the Rho-kinase pathway2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] High concentrations of landiolol, a β1-adrenoceptor antagonist, stimulates smooth muscle contraction of the rat trachea through the Rho-kinase pathway2008

Author(s)

Journal Title

Data Source

[Journal Article] Anticholinesterase drugs stimulate smooth muscle contraction of the rat trachea through the Rho-kinase pathway.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Anticholine sterase dmgs stimulate smooth muscle contraction of the rat trachea through the Rho-kinase pathway2006

Author(s)

Journal Title

Data Source

SHIBATA Osamu 柴田治

柴田治シバタオサム