Sugiyama Kiyoshi 杉山清

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SUGIYAMA Kiyoshi 杉山清

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Researcher Number	80145713
Other IDs	https://orcid.org/0000-0001-5558-9906
External Links
Affiliation (Current)	2025: 星薬科大学, 薬学部, 特任教授
Affiliation (based on the past Project Information) *help	2010: 星薬科大学, 薬学部, 教授 2008: Hoshi University, 教授 2008: Hoshi University, 星薬科大学, 教授 2007 – 2008: Hoshi University, 薬学部, 教授 2003 – 2005: Hoshi University, Faculty of Pharmacy, professor, 薬学部, 教授 2002: 星薬科大学, 薬学部, 助教授
Review Section/Research Field	Principal Investigator Medical pharmacy / General internal medicine (including Psychosomatic medicine) Except Principal Investigator Obstetrics and gynecology / Medical pharmacy
Keywords	Principal Investigator Germ Freeマウス / 薬物動態 / 薬物代謝 / CYP3A / 抗生物質 / 核内受容体 / FXR / PXR / シプロフロキサシン / リトコール酸 … More / チトクロムP450 / 腸内細菌 / PPARγ / 黄連解毒湯 / 脂肪細胞 / PPAR_Y / berberine / KK-A^yマウス / 抗肥満作用 … More Except Principal Investigator GVH / MHC / cell traffic / auto immunity / CD4 T cell / MHC restriction / pregnancy / materno-fatal relation / 母子間細胞移行 / 自己免疫疾患 / CD_4^+T細胞 / MHC拘束性 / 妊娠 / 母子免疫 / Cyp3a / 肥満 / 薬物動態 / 薬物間相互作用 / 糖尿病治療薬 / 薬物トランスポーター / 薬物代謝酵素 / 薬物動態変動 / 糖尿病 Less

Alteration in the drug disposition in the mouse model of diabetes/obesity.
- Principal Investigator
  
  ITO Kiyomi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Hoshi University
Effects of intestinal flora on cytochrome P450 and transporterPrincipal Investigator
- Principal Investigator
  
  SUGIYAMA Kiyoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Hoshi University
脂肪組織からのアディポサイトカイン産生・分泌に及ぼす漢方薬の影響Principal Investigator
- Principal Investigator
  
  杉山清
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Hoshi University
Maternal Fatal cell traffic by DNA analysis and New approach for Autoinunune disorder
- Principal Investigator
  
  YAMAGUCHI Nobuo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KANAZAWA MEDICAL UNIVERSITY

All 2010 2009 2008 2004 Other

All Journal Article Presentation

[Journal Article] Differences in the pharmacokinetics of Cyp3a substrates in TSOD and streptzotocin-induced diabetic mice2010
- Author(s)
  Kudo T., Toda T., Ushiki T., Ohi K., Ikarashi N., Ochiai W., Sugiyama K.
- Journal Title
  
  Xenobiotica 40(4)
  
  Pages: 282-290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590160
[Journal Article] Use of clearance concepts and modeling techniques in the prediction of metabolic drug-drug interactions.2010
- Author(s)
  Ito, K., Sugiyama, Y.
- Journal Title
  
  Trends Pharmacol.Sci.
  
  Volume: 31 Pages: 351-355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590160
[Journal Article] Use of clearance concepts and modeling techniques in the prediction of metabolic drug-drug interactions2010
- Author(s)
  Ito K., Sugiyama Y.
- Journal Title
  
  Trends Pharmacol. Sci. 31(8)
  
  Pages: 351-355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590160
[Journal Article] Intestinal flora induces the expression of Cyp3a in the mouse liver2009
- Author(s)
  Takahiro Toda, Nobutomo Ikarashi, Kiyomi Ito, Kiyoshi Sugiyama et.al.
- Journal Title
  
  Xenobiotica 39
  
  Pages: 323-334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590163
[Journal Article] 抗生物質を投与するとリトコール酸産生菌の減少に伴ってマウスの肝臓におけるCyp3aが減少する2009
- Author(s)
  戸田雄大, 五十嵐信智, 伊藤清美, 杉山清, 他
- Journal Title
  
  YAKUGAKU ZASSHI 129
  
  Pages: 601-608
- NAID
  130000136164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590163
[Journal Article] Alterd expression of CYP in TSOD mice : a model of type 2 diabetes and obesity2009
- Author(s)
  Kudo T., Shimada T., Toda T., Igeta S., Suzuki W., Ikarashi N., Ochiai W., Ito K., Aburada M., Sugiyama K.
- Journal Title
  
  Xenobiotica 39(12)
  
  Pages: 889-902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590160
[Journal Article] 抗肥満作用を有する生薬の検索2004
- Author(s)
  杉山清
- Journal Title
  
  日本薬学会第124年会要旨集 4
  
  Pages: 54-54
- Data Source
  KAKENHI-PROJECT-16659176
[Journal Article] Ciprofloxacin suppresses Cyp3a in the mouse liver by reducing lithocholic acid-producing intestinal flora
- Author(s)
  Takahiro Toda, Nobutomo Ikarashi, Kiyomi Ito, Kiyoshi Sugiyama et.al.
- Journal Title
  
  Drug Metab. Pharmacokinet. (in press)
- NAID
  10025723402
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590163
[Presentation] 肝臓における薬物トランスポーターの発現に及ぼす腸内細菌の影響2008
- Author(s)
  大井かんな, 五十嵐信智, 伊藤清美, 杉山清, 他
- Organizer
  医療薬学フォーラム2008/第16回クリニカルファーマシーシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590163
[Presentation] 肝臓におけるCYPの発現に及ぼす腸内細菌の影響2008
- Author(s)
  戸田雄大, 五十嵐信智, 伊藤清美, 杉山清, 他
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590163
[Presentation] 肝臓におけるCYPの発現に及ぼす腸内細菌の影響2008
- Author(s)
  戸田雄大, 五十嵐信智, 伊藤清美, 杉山清, 他
- Organizer
  第25回和漢医薬学会大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590163
[Presentation] Effect of intestinal microbiota on the expression of CYP enzymes2008
- Author(s)
  Kiyomi Ito, Nobutomo Ikarashi, Kiyoshi Sugiyama et.al.
- Organizer
  23^<rd> the Japanese Society for the Study of Xenobiotics Annual Meeting
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-19590163
[Presentation] 肝臓における薬物トランスポーターの発現に及ぼす腸内細菌の影響2008
- Author(s)
  井桁慎太郎, 五十嵐信智, 伊藤清美, 杉山清, 他
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590163

1. ITO Kiyomi (60232435)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
2. IKARASHI Nobutomo (40409363)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. KUDO Toshiyuki (10584815)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. YAMAGUCHI Nobuo (10106916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NORIYOSHI Ogawa (80308618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. IKAWA Hiromichi (20124935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MATSUBA Shintaro (40367462)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SHIMIZU Shoji (30150759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 宗志平 (80216572)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Sugiyama Kiyoshi 杉山 清

SUGIYAMA Kiyoshi 杉山 清

Research Projects

Research Products

Co-Researchers

Alteration in the drug disposition in the mouse model of diabetes/obesity.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of intestinal flora on cytochrome P450 and transporterPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脂肪組織からのアディポサイトカイン産生・分泌に及ぼす漢方薬の影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Maternal Fatal cell traffic by DNA analysis and New approach for Autoinunune disorder

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Differences in the pharmacokinetics of Cyp3a substrates in TSOD and streptzotocin-induced diabetic mice2010

Author(s)

Journal Title

Data Source

[Journal Article] Use of clearance concepts and modeling techniques in the prediction of metabolic drug-drug interactions.2010

Author(s)

Journal Title

Data Source

[Journal Article] Use of clearance concepts and modeling techniques in the prediction of metabolic drug-drug interactions2010

Author(s)

Journal Title

Data Source

[Journal Article] Intestinal flora induces the expression of Cyp3a in the mouse liver2009

Author(s)

Journal Title

Data Source

[Journal Article] 抗生物質を投与するとリトコール酸産生菌の減少に伴ってマウスの肝臓におけるCyp3aが減少する2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Alterd expression of CYP in TSOD mice : a model of type 2 diabetes and obesity2009

Author(s)

Journal Title

Data Source

[Journal Article] 抗肥満作用を有する生薬の検索2004

Author(s)

Journal Title

Data Source

[Journal Article] Ciprofloxacin suppresses Cyp3a in the mouse liver by reducing lithocholic acid-producing intestinal flora

Author(s)

Journal Title

NAID

Data Source

[Presentation] 肝臓における薬物トランスポーターの発現に及ぼす腸内細菌の影響2008

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 肝臓におけるCYPの発現に及ぼす腸内細菌の影響2008

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 肝臓におけるCYPの発現に及ぼす腸内細菌の影響2008

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Effect of intestinal microbiota on the expression of CYP enzymes2008

Author(s)

Sugiyama Kiyoshi 杉山清

SUGIYAMA Kiyoshi 杉山清