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IKOTA Nobuo  伊古田 暢夫

ORCIDConnect your ORCID iD *help
… Alternative Names

伊古田 暢夫  イコタ ノブオ

NOBUO IKOTA  伊古田 暢夫

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Researcher Number 80159649
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2007 – 2008: Shujitsu University, 薬学部, 教授
2006: National Institute of Radiological Sciences, Researcher, 放射線医学総合研究所, 研究員
2006: National Institute of Radiological Sciences, Director of Special Research, 特別上席研究員
2005 – 2006: 放射線医学総合研究所, 研究員
2004 – 2005: 独立行政法人放射線医学総合研究所, レドックス制御研究グループ, グループリーダー … More
2002: National Institute of Radiological Sciences, Redox Regulation Research group, Group Leader, レドックス制御研究グループ, グループリーダ
2001: 放射線医学総合研究所, レドックス制御研究グループ, グループリーダー
2000: National Institute of Radiological Sciences, 1st Research group, subgroup leader, 第一研究グループ, サブグループリーダー
1999 – 2000: 放射線医学総合研究所, 第一研究グループ, 研究員
1995: 放射線医学総合研究所, 第一研究グループ・第四サブグループリーダー
1994: 放射線医学総合研究所, 薬理化学研究部, 主任研究官
1990: 放射線医学総合研究所, 薬理化学研究部, 主任研究官
1988: National Institute of Radiological Sciences, 薬理化学研究部, 主任研究官
1987: 放射線医学総合研究所, 化学薬学研究部, 主任研究官 Less
Review Section/Research Field
Principal Investigator
Chemical pharmacy / 医薬分子機能学 / Drug development chemistry
Except Principal Investigator
Physical pharmacy
Keywords
Principal Investigator
superoxide / reactive oxygen species / 抗酸化剤 / スーパーオキシド / 活性窒素 / 活性酸素 / スワインソニン / AI-77-B / antioxidant / hydroxyl radical … More / peroxynitrite / reactive nitrogen species / ヒドロキシルラジカル / パーオキシナイトライト / 放射線防護剤 / ポリヒドロキシピロリジン / (S)-ピログルタミン酸 / (S)ーピログルタミン酸 / 免疫賦活物質 / 光学活性化合物 / Geissmann-Waiss lactone / swainsonine / (S)-pyroglutamic acid / immunomodulator / glycosidase inhibitor / optically active compound / (S)-グルタミン酸 / キャスタノスペルミン / 免疫賊活物質 / バーチ還元 / ガイスマン-バイス ラクトン / 立体選択的合成 / AIー77ーB / ガイスマン・バイス ラクトン / グリコシダーゼ阻害物質 / vitamin E derivatives / radioprotector / bioregulation substances / free radical / インドール / ラジカル消去剤 / ラジカル / ESR / 活性酸素消去剤 / ビタミンE誘導体 / 生体制御物質 / フリーラジカル / redox regulation / oxidative stress / DMPO / レドックス制御 / 酸化ストレス / polyphenol / spintrapping method / nitrotyrosine / ジチロシン / フラボノイド / ポリフェノール / スピントラッピング法 / ニトロチロシン / 放射線 / 生理活性 / 薬学 / 有機化学 / 生理活性物質 / 酸化的障害 / 酸化的ストレス / アレキシン / 重複不斉反応 / アニソマイシン / α,β-不飽和-トランス-エステル / 立体選択的アリル化 / D-リボノラクトン / シス-ジヒドロキシル化 / α、β-不飽和ラクタム / 立体選択的アリル化反応 … More
Except Principal Investigator
ESR / Imaging / Nitroxyl radical / Redox / Oxidative stress / 両像解析 / 酸化的ストレス / 画像解析 / ニトロキシルラジカル / 生体レドックス / 酸化ストレス Less
  • Research Projects

    (9 results)
  • Research Products

    (118 results)
  • Co-Researchers

    (7 People)
  •  Studies on Development of Protective Compounds against Oxidative DamagesPrincipal Investigator

    • Principal Investigator
      IKOTA Nobuo
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Shujitsu University
  •  Study on non-invasive measurement of biological redox for diagnosis of chronic diseases

    • Principal Investigator
      TAKESHITA Keizo
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Sojo University
  •  Study on Development of Bio-Regulatative Substances Against Free Radicals.Principal Investigator

    • Principal Investigator
      IKOTA Nobuo
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      National Institute of Radiological Sciences
  •  Study on Development of Redox Regulatative Substances Against Oxidative Stress.Principal Investigator

    • Principal Investigator
      ITOKA Nobuo
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      医薬分子機能学
    • Research Institution
      National Institute of Radiological Sciences
  •  Study on Development of Bioregurative Substances Related with Generation and Elimination for Active Oxygen and Nitrogen Species.Principal Investigator

    • Principal Investigator
      IKOTA Nobuo
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      医薬分子機能学
    • Research Institution
      National Institute of Radiological Sciences
  •  光学活性なポリヒドロキシアミン類の立体選択的な合成研究Principal Investigator

    • Principal Investigator
      伊古田 暢夫
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      National Institute of Radiological Sciences
  •  光学活性なヒドロキシピロリジノン誘導体を用いる生理活性物質の合成Principal Investigator

    • Principal Investigator
      伊古田 暢夫
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      National Institute of Radiological Sciences
  •  光学活性な免疫賦活物質の合成Principal Investigator

    • Principal Investigator
      伊古田 暢夫
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      National Institute of Radiological Sciences
  •  Studies on the synthesis of optically active glycosidase inhibitorsPrincipal Investigator

    • Principal Investigator
      NOBUO IKOTA
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      National Institute of Radiological Sciences

All 2009 2008 2007 2006 2005 2004 2001 2000 1999

All Journal Article Presentation Book Patent

  • [Book] 生体内一酸化窒素(NO)実験プロトコール2000

    • Author(s)
      中川秀彦, 小澤俊彦, 伊古田暢夫 (分担), 吉村哲彦編
    • Total Pages
      288
    • Publisher
      共立出版
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-11672222
  • [Journal Article] Heat-Treated Mineral-Yeast as a Potent Post-irradiation Radioprotector2008

    • Author(s)
      Kazunori Anzai, Nobuo Ikota, Megumi Ueno, Minako Nyui, Tsutomu V. Kagiya
    • Journal Title

      J. Radiat. Res. 49

      Pages: 425-430

    • NAID

      110006820182

    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Modification of Nitroxyl Contrast Agents with Multiple Spins and Their Proton T_1 Relaxivity.2008

    • Author(s)
      K. Matsumoto, H. Yakumaru, M, Narazaki, Nakagawa. K. Anzai, H. I kehira. N. Ikota
    • Journal Title

      Magn. Reson. Imaging査読有 26

      Pages: 117-121

    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Heavy-ion Induced Scrose and L-α-Alanine Radicals Investigated by EPR2008

    • Author(s)
      Kouichi Nakagawa, Nobuo Ikota, Yukio Sato
    • Journal Title

      Appl. Magn. Reson. 査読有 33

      Pages: 111-116

    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Scrose radical-production cross section regarding heavy-ion irradiation, Spectrochimica Acta Part A2008

    • Author(s)
      Kouichi Nakagawa, Nobuo Ikota, and Kazunori Anzai
    • Journal Title

      Molecular and Biomolecular Spectroscopy 63

      Pages: 1384-1387

    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Effect of Methyl Substitution on Antioxidative Property and Genotoxicity of Resveratrol2008

    • Author(s)
      Kiyoshi Fukuhara, Ikuo Nakanishi, Atsuko Matsuoka, Tomohiro Matsumura, S. Honda, M. Hayashi, Y. Matsuda, Toshihiko Ozawa, Khinichi Saito, Nobuo Ikota, Haruhiro Okuda
    • Journal Title

      Chem. Res. Toxicol. 査読有 21

      Pages: 282-287

    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Heavy-ion Induced Scrose and L-α-Alanine Radicals Investigated by EPR2008

    • Author(s)
      Kouichi Nakagawa, Nobuo Ikota, and Yukio Sato
    • Journal Title

      Appl. Magn. Reson 33

      Pages: 111-116

    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Modification of Nitroxyl Contrast Agents with Multiple Spins and Their Proton T_1 Relaxivity2008

    • Author(s)
      K. Matsumoto, H. Yakumaru, M. Narazaki, H. Nakagawa, K. Anzai, H.I kehira, N. Ikota
    • Journal Title

      Magn. Reson. Imaging 26

      Pages: 117-121

    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Enhanced Radical-Scavenging Activity of Naturally-Oriented Artepillin C Derivatives2008

    • Author(s)
      Sushma Manda, Ikuo Nakanishi, Kei Ohkubo, Yoshihiro Uto, Tomonori Kawashima, Kiyoshi Fukuhara, Haruhiro Okuda, Hitoshi Hori, Toshihiko Ozawa, Nobuo Ikota, Shunichi Fukuzumi, and Kazunori Anzai
    • Journal Title

      Chem. Commun.

      Pages: 626-628

    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Effect of Methyl Substitution on Antioxidative Property and Genotoxicity of Resveratrol2008

    • Author(s)
      Kiyoshi Fukuhara, Ikuo Nakanishi, Atsuko Matsuoka, Tomohiro Matsumura, S. Honda, M. Hayashi, Y. Matsuda, Toshihiko Ozawa, Shinichi Saito, Nobuo Ikota, and Haruhiro Okuda
    • Journal Title

      Chem. Res. Toxicol. 21

      Pages: 282-287

    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Heat-Treated Mineral-Yeast as a Potent Post-irradiation Radioprotector2008

    • Author(s)
      Kazunori Anzai, Nobuo Ikota. Megumi Ueno Minako Nyui, Tsutomu V. Kagiya
    • Journal Title

      J. Radiat. Res. 査読有 49

      Pages: 425-430

    • NAID

      110006820182

    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Scrose radical-production cross section regarding heavy-ion irradiation2008

    • Author(s)
      Kouichi Nakagawa, Nobuo Ikota, Kazunori Anzai.
    • Journal Title

      Spectrochimica Ada Part A査読有 63

      Pages: 1384-1387

    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Enhanced Radical-Scavenging Activity of Naturally-Oriented Artepillin C Derivatives2008

    • Author(s)
      Sushma Manda, Ikuo Nakanishi, Kei Ohkubo Yoshihiro Uto, Tomonori Kawashima, Kiyosh Fukuhara, Haruhiro Okuda, Hitoshi Hori, Toshihiko Ozawa, Nobuo Ikota, Shunich Fukuzumi, Kazunori Anzai
    • Journal Title

      Chem. Commun. 査読有 21

      Pages: 626-628

    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Comparisons of EPR imaging and T1-weighted MRI for Efficient Detection of Nitroxyl Contrast Agents2007

    • Author(s)
      K. Matsumoto, M. Narazaki, H. Ikehira, K. Anzai, N. Ikota
    • Journal Title

      J. Magn. Reson. 187

      Pages: 155-162

    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Scandium Ion-accelated Scavenging Reaction of Cumylperoxyl Radical by a Cyclic Nitroxyl Radical via Electron Transfer2007

    • Author(s)
      Ikuo Nakanishi, Kumiko Kawaguchi, Kei Ohkubo, Tomonori Kawashima, Sushma Manda, Hideko Kanazawa, Keizo Takeshita, Kazunori Anzai, Toshihiko Ozawa, Shunichi Fukuzumi, and Nobuo Ikota
    • Journal Title

      Chem. Lett. 36

      Pages: 378-379

    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Scandium Ion-accelerated Scavenging Reaction of Cumylperoxyl Radical by a Cyclic Nitroxyl Radical via Electron Transfer2007

    • Author(s)
      I.Nakanishi, K.Kawaguchi, K.Ohkubo, T.Kawashima, S.Manda, H.Kanazawa, K.Takeshita, K.Anzai, T.Ozawa, S.Fukuzumi, N.Ikota
    • Journal Title

      Chem. Lett.

    • NAID

      10018829397

    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] A Long-Lived o-Semiquinone Radical Anion is Formed from N--alanyl-5-S-glutathionyl-3,4-dihydroxy-phenylalanine (5-S-GAD), an Insect-derived Antibacte- rial Substance2007

    • Author(s)
      Nobuko Akiyama, Ikuo Nakanishi, Kei Ohkubo, Kazue Satoh, Koichiro Tsuchiya, Takeshi Nishikawa, Shunichi Fukuzumi, Nobuo Ikota, Toshihiko Ozawa, Masafumi Tsujimoto, and Shunji Natori
    • Journal Title

      J. Biochem. 142

      Pages: 41-48

    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Nitration of Specific Tyrosine Residues of Cytochrome c Is Associated with Caspase-cascade Inactivation.2007

    • Author(s)
      H.Nakagawa, N.Komai, M.Takusagawa, Y.Miura, T.Toda, N.Miyata, T.Ozawa, N.Ikota.
    • Journal Title

      Biol. Pharm. Bull. 30

      Pages: 15-20

    • NAID

      110006153259

    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Scandium Ion-accelated Scavenging Reaction of Cumylperoxyl Radical by a Cyclic Nitroxyl Radical via Electron Transfer2007

    • Author(s)
      Ikuo Nakanishi, Kumiko Kawaguchi, Kei Ohkubo, Tomonori Kawashima, Sushma Manda, Hideko Kanazawa, Keizo Takeshita, Kazunori Anzai, Toshihiko Ozawa, Shunichi Fukuzumi, Nobuo Ikota
    • Journal Title

      Chem.Lett 36

      Pages: 378-379

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Nitration of Specific Tyrosine Residues of Cytochrome c is Associated with Caspase- cascade Inactivation2007

    • Author(s)
      Hidehiko Nakagawa, Nobuko Komai, Mitsuko Takusagawa, Yuri Miura, Tosifusa Toda, Naoki Miyata, Toshihiko Ozawa, and Nobuo Ikota
    • Journal Title

      Biol. Pharm. Bull. 30

      Pages: 15-20

    • NAID

      110006153259

    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Effect of Solvent Polarity on the One-Electron Oxidation of Cyclic Nitroxyl Radicals2007

    • Author(s)
      Sushma Manda, Ikuo Nakanishi, Kei Ohkubo, Tomonori Kawashima, Ken-ichiro Matsumoto, Toshihiko Ozawa, Shunichi Fukuzumi, Nobuo Ikota, Kazunori Anzai
    • Journal Title

      Chem.Lett 36

      Pages: 914-915

    • NAID

      10019745653

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Scandium ion-accelerated scavenging reaction of cumylperoxyl radical by a cyclic nitroxyl radical via electron transfer.2007

    • Author(s)
      Ikuo Nakanishi, Kumiko Kawaguchi, Kei Ohkubo, Tomobori Kawashima, Sushma Manda, Hideko Kanazawa, Keizo Takeshita, Kazunori Anzai, Toshihiko Ozawa, Shunichi Fukuzumi, Nobuo Ikota
    • Journal Title

      Chem.Lett. 36(3)

      Pages: 378-379

    • NAID

      10018829397

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590047
  • [Journal Article] Nitration of Specific TyrosineResidues of Cytochrome c is Associated with Caspase-cascade Inactivation2007

    • Author(s)
      Hidehiko Nakagawa, Nobuko Komai, Mitsuko Takusagawa, Yuri Miura, Tosifusa Toda, Naoki Miyata, Toshihiko Ozawa, Nobuo Ikota
    • Journal Title

      Biol.Pharm.Bull 30

      Pages: 15-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Nitroxyl radicals: Electrochemical redox behaviour and structure-activity relationships2007

    • Author(s)
      Sushma Manda, Ikuo Nakanishi, Kei Ohkubo, Haruko Yakumaru, Ken-ichiro Matsumoto, Toshihiko Ozawa, Nobuo Ikota, Shunichi Fukuzumi, and Kazunori Anzai
    • Journal Title

      Org. Biomol. Chem. 5

      Pages: 3951-3955

    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Involvement of Electron Transfer in the Radical-Scavengvng Reaction of Resveratrol2007

    • Author(s)
      Ikuo Nakanishi, Tomokazu Shimada, Kei Ohkubo, Sushma Manda, Takehiko Shimizu, Shiro Urano, Haruhiro Okuda, Naoki Miyata, Toshihiko Ozawa, Kazunori Anzai, Shunichi Fukuzumi, Nobuo Ikota, Kiyoshi Fukuhazr
    • Journal Title

      Chem.Let 36

      Pages: 1276-1277

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Involvement of Electron Transfer in the Radical-Scavenging Reaction of Resveratrol2007

    • Author(s)
      Ikuo Nakanishi, Tomokazu Shimada, Kei Ohkubo, Sushma Manda, Takehiko Shimizu, Shiro Urano, Haruhiro Okuda, Naoki Miyata, Toshihiko Ozawa, Kazunori Anzai, Shunichi Fukuzumi, Nobuo Ikota, and Kiyoshi Fukuhara
    • Journal Title

      Chem. Lett. 36

      Pages: 1276-1277

    • NAID

      10019962015

    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] A Long-Lived o-Semiquinone Rdical Anion is Formed from N-β-alanyl-5-S-glutathionyl-3,4-dihydroxy-phenylalanine(5-S-GAD),an Insect-derived Antibacterial Substance2007

    • Author(s)
      Nobuko Akiyama, Ikuo Nakanishi, Kei Ohkubo, Kazue Satoh, Koichiro Tsuchiya, Takeshi Nishikawa, Shunichi Fuzumi, Nobuo Ikota, Toshihiko Ozawa, Masafumi Tsujimoto, Shunji Natori
    • Journal Title

      J. Biochem 142

      Pages: 41-48

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Comparisons of EPR imaging and T_1-weighted MRI for Efficient Detection of Nitroxyl Contrast Agents2007

    • Author(s)
      K. Matsumoto, M. Narazaki, H. Ikehira, K. Anzai, N. Ikota
    • Journal Title

      J.Magn.Reson 187

      Pages: 155-162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Effect of Solvent Polarity on the One-Electron Oxidation of Cyclic Nitroxyl Radicals2007

    • Author(s)
      Sushma Manda, Ikuo Nakanishi, Kei Ohkubo, Tomonori Kawashima, Ken-ichiro Matsumoto, Toshihiko Ozawa, Shunichi Fukuzumi, Nobuo Ikota, and Kazunori Anzai
    • Journal Title

      Chem. Lett. 36

      Pages: 914-915

    • NAID

      10019745653

    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Nitroxyl radicals:Electrochemical redox behaviour and structure-activity relationships2007

    • Author(s)
      Sushma Manda, Ikuo Nakanishi, Kei Ohkubo, Haruko Yakumazu, Ken-ichiro Matsumoto, Toshihiko Ozawa, Nobuo Ikota, Shunichi Fukuzumi, Kazunori Anzai
    • Journal Title

      Org.Biomol.Chem 5

      Pages: 3951-3955

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Journal Article] Structural Basis for DNA-Cleaving Activity of Resveratrol in the Presence of Cu(II)2006

    • Author(s)
      K.Fukuhara, M.Nagakawa, I.Nakanishi, K.Ohkubo, K.Imai, S.Urano, S.Fukuzumi, T.Ozawa, N.Ikota, M.Mochizuki, N.Miyata, H.Okuda
    • Journal Title

      Bioorganic & Medicinal Chemistry 14(5)

      Pages: 1437-1443

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Comparison of Stable Nitroxide, 3-Substituted PROXYLs, with Respect to Protection from Radiation, Prevention of DNA Damage and Distribution in Mice2006

    • Author(s)
      Kazunori Anzai, Megumi Ueno, Akira Yoshida, Masako Furuse, Winn Aung, Ikuo Nakanishi, Takashi Moritake, Keizo Takeshita, Nobuo Ikota
    • Journal Title

      Free Radic.Biol.Med. 40(7)

      Pages: 1170-1178

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590047
  • [Journal Article] Structural Basis for DNA-Cleaving Activity of Resveratrol in the Presence of Cu(II)2006

    • Author(s)
      K.Fukuhara, I.Nakanishi, S.Fukuzumi, N.Ikota, M.Mochizuki, N.Miyata, et al.
    • Journal Title

      Bioorganic Medicinal Chemistry 14

      Pages: 1437-1443

    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Structural Basis for DNA-Cleaving Activity of Resveratrol in the Presence of Cu(II)2006

    • Author(s)
      K.Fukuhara, M.Nagakawa., I.Nakanishi, K.Ohkubo., K.Imai., S.Urano., S.Fukuzumi., T.Ozawa, N.Ikota, M.Mochizuki., N.Miyata., H.Okuda
    • Journal Title

      Bioorganic & Medicinal Chemistry 14

      Pages: 1437-1443

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Comparison of Stable Nitroxide, 3-Substituted 2,2,5,5-tetramethylpyrrolidine-N-oxyls, with Respect to Protection from Radiation, Prevention of DNA Damage and Distribution in Mice2006

    • Author(s)
      K.Anzai, M.Ueno, I.Nakanishi, N.Ikota, et al.
    • Journal Title

      Free Radical Biology and Medicine 40

      Pages: 1170-1178

    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Planar Catechin Analogues with Alkyl Side Chains : A Potent Antioxidant and an alpha-Glucosidase Inhibitor2006

    • Author(s)
      W.Hakamata., I.Nakanishi, Y.Masuda., T.Shimizu., H.Higuchi., Y.Nakamura., S.Saito., S.Urano., T.Oku., T.Ozawa, N.Ikota, N.Miyata, H.Okuda., K.Fukuhara.
    • Journal Title

      Journal of the American Chemical Society 128

      Pages: 6524-6525

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Planar Catechin Analogues with Alkyl Side Chains : A Potent Antioxidant and an alpha-Glucosidase Inhibitor2006

    • Author(s)
      W.Hakamata, I.Nakanishi, Y.Masuda, T.Shimizu, H.Higuchi, Y.Nakamura, S.Saito, S.Urano, T.Oku, T.Ozawa, N.Ikota, N.Miyata, H.Okuda, K.Fukuhara
    • Journal Title

      Journal of the American Chemical Society 128

      Pages: 6524-6525

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Drastic effect of several caffeic acid derivatives on the induction of heme oxygenase-1 expression revealed by quantitative real-time RT-PCR2006

    • Author(s)
      K.Suzuki, I.Tanaka, I.Nakanishi, A.Kurematsu, H.Yakumaru, N.Ikota, H.Ishihara
    • Journal Title

      BioFactors 28

      Pages: 151-158

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Comparison of Stable Nitroxide, 3-Substituted 2,2,5,5-tetramethylpyrrolidine-N-oxyls, with Respect to Protection from Radiation, Prevention of DNA Damage and Distribution in Mice2006

    • Author(s)
      K.Anzai, M.Ueno, A.Yoshida, M.Furuse, A.Winn, I.Nakanishi, T.Moritake, K.Takeshita, N.Ikota
    • Journal Title

      Free Radical Biology and Medicine 40

      Pages: 1170-1178

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Hydroxyl radical generation via photoreduction of a simple pyridine N-oxide by an NADH analogue2005

    • Author(s)
      Ikuo Nakanishi, Chiho Nishizawa, Kei Ohkubo, Keizo Takeshita, Kazuo T.Suzuki, Toshihiko Ozawa, Sidney M.Hecht, Masayuki Tanno, Shoko Sueyoshi, Naoki Miyata, Haruhiro Okuda, Shunichi Fukuzumi, Nobuo Ikota, Kiyoshi Fukuhara
    • Journal Title

      Org.Biomol.Chem. 3(18)

      Pages: 2363-3265

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590047
  • [Journal Article] Hydroxyl Radical Generation via Photoreduction of a Simple Pyridine N-Oxide by an NADH Analogue.2005

    • Author(s)
      Ikuo Nakanishi, Chiho Nishizawa, Toshihiko Ozawa, Nobuo Ikota, Kiyoshi Fukuhara et al.
    • Journal Title

      Org.Biomol.Chem. 3

      Pages: 3263-3265

    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Evaluation of Distribution Patterns for Copper and Zink in Metallothionein and Superoxide Dismutase in Chronic Liver Diseases and Hepatocellular Carcinoma Using High-Performance Liquid Chromatography(HPLC).2005

    • Author(s)
      S.Kubo, H.Fukuda, M.Ebara, N.Ikota, H.Saisho, H.Nakagawa, T.Ozawa, et al.
    • Journal Title

      Biol.Pharm.Bull. 28

      Pages: 1137-1141

    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Quantitative measurements of oxidative stress in mouse skin induced by X-ray irradiation2005

    • Author(s)
      C.Cuiping, R.Tanaka, Y.Okuda, N.Ikota, H.Yamamoto., S.Urano., T.Ozawa, K.Anzai
    • Journal Title

      Chemical & Pharmaceutical Bulletin 53

      Pages: 1411-1415

    • NAID

      10016784293

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Quantitative measurements of oxidative stress in mouse skin induced by X-ray irradiation2005

    • Author(s)
      C.Cuiping, R.Tanaka, Y.Okuda, N.Ikota, H.Yamamoto, S.Urano, T.Ozawa, K.Anzai
    • Journal Title

      Chemical & Pharmaceutical Bulletin 53(11)

      Pages: 1411-1415

    • NAID

      10016784293

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] N-[18F]Fluoroethylpiperidin-4ylmethyl Acetate, a Novel Lipophilic Acetylcholine Analogue for PET Measurement of Brain Acetylcholinesterase Activity2005

    • Author(s)
      T.Kikuchi, M.Zhang, N.Ikota, K.Fukushi, T.Okamura, K.Suzuki, Y.Arano, T.Irie
    • Journal Title

      Journal of Medicinal Chemistry 48

      Pages: 2577-2583

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Electron-Transfer Mechanism in Radical-Scavenging Reactions by a Vitamin E Model in a Protic Medium2005

    • Author(s)
      I.Nakanishi, T.Kawashima, K.Ohkubo., H.Kanazawa., K.Inami., M.Mochizuki., K.Fukuhara., H.Okuda., T.Ozawa, S.Itoh., S.Fukuzumi., N.Ikota
    • Journal Title

      Organic & Biomolecular Chemistry 3

      Pages: 626-629

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] N-[18F]Fluoroethylpiperidin-4ylmethyl acetate, a Novel Lipophilic Acetylcholine Analogue for PET Measurement of Brain Acetylcholinesterase Activity2005

    • Author(s)
      Tatsuya Kikuchi, Nobuo Ikota, Kazutoshi Suzuki, Yasushi Arano, Toshiaki Irie et al.
    • Journal Title

      Journal of Medicinal Chemistry 48

      Pages: 2577-2583

    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Hydroxyl Radical Generation via Photoreduction of a Simple Pyridine N-Oxide by an NADH Analogue2005

    • Author(s)
      I.Nakanishi, C.Ni shizawa, K.Ohkubo, K.Takeshita, K.Suzuki, T.Ozawa, S.Hecht, M.Tanno, S.Sueyoshi, N.Miyata, H.Okuda, S.Fukuzumi, N.Ikota, K.Fukuhara
    • Journal Title

      Organic & Biomolecular Chemistry 3(18)

      Pages: 3263-3265

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Quantitative measurements of oxidative stress in mouse skin induced by X-ray irradiation2005

    • Author(s)
      Cuiping Chi, Ryoko Tanaka, Yohei Okuda, Nobuo Ikota, Toshihiko Ozawa, Kazunori Anzai, et al.
    • Journal Title

      Chem.Pharm.Bull. 53

      Pages: 1411-1415

    • NAID

      10016784293

    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] In-vivo PET imaging of inducible D2R reporter transgene expression using [11C]FLB 457 as reporter probe in living rats2005

    • Author(s)
      A.Winn, T.Okauchi, M.Satou, T.Saito, H.Nakagawa, H.Ishihara, N.Ikota, T.Suhara, K.Anzai
    • Journal Title

      Nuclear Medicine Communications 26(3)

      Pages: 259-268

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] N-[18F]Fluoroethylpiperidin-4ylmethyl Acetate, a Novel Lipophilic Acetylcholine Analogue for PET Measurement of Brain Acetylcholinesterase Activity2005

    • Author(s)
      T.Kikuchi, M.Zhang, N.Ikota, K.Fukushi, T.Okamura, K.Suzuki, Y.Arano, T.Irie
    • Journal Title

      Journal of Medicinal Chemistry 48(7)

      Pages: 2577-2583

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Electron-Transfer Mechanism in Radical-Scavenging Reactions by a Vitamin E Model in a Protic Medium2005

    • Author(s)
      I.Nakanishi, T.Kawashima, K.Ohkubo, H.Kanazawa, K.Inami, M.Mochizuki, K.Fukuhara, H.Okuda, T.Ozawa, S.Itoh, S.Fukuzumi, N.Ikota
    • Journal Title

      Organic & Biomolecular Chemistry 3(4)

      Pages: 626-629

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] In-vivo PET imaging of inducible D2R reporter transgene expression using [11C]FLB 457 as reporter probe in living rats2005

    • Author(s)
      A.Winn, T.Okauchi, M.Satou, T.Saito, H.Nakagawa, H.Ishihara, N.Ikota, T.Suhara, K.Anzai
    • Journal Title

      Nuclear Medicine Communications 26

      Pages: 259-268

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Hydroxyl Radical Generation via Photoreduction of a Simple Pyridine N-Oxide by an NADH Analogue2005

    • Author(s)
      I.Nakanishi, C.Nishizawa, K.Ohkubo, K.Takeshita, K.Suzuki, T.Ozawa, S.Hecht., M.Tanno., S.Sueyoshi., N.Miyata., H.Okuda, S.Fukuzumi., N.Ikota, K.Fukuhara
    • Journal Title

      Organic & Biomolecular Chemistry 3

      Pages: 3263-3265

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Electron-transfer Mechanism in Radical-scavenging Reactions by a Vitamin E Model in a Protic Media2005

    • Author(s)
      Ikuo Nakanishi, Tomonori Kawasima, Masataka Mochizuki, Nobuo Ikota, et al.
    • Journal Title

      Organic Biomolecular Chemistry 3

      Pages: 626-629

    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Biting reduces acute stress-induced oxidative stress in the rat hypothalamus2005

    • Author(s)
      S.Miyake, K.Anzai, N.Ikota, T.Ozawa, M.Toyoda, S.Sato, M-C-i Lee, et al.
    • Journal Title

      Redox Report. 10

      Pages: 19-24

    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Biting reduces acute stress-induced oxidative stress in the rat hypothalamus2005

    • Author(s)
      S.Miyake., K.Sasaguri., N.Hori., H.Shoji., F.Yoshino., H.Miyazaki., K.Anzai, N.Ikota, T.Ozawa, M.Toyoda, S.Sato, M.Lee
    • Journal Title

      Redox Report 10

      Pages: 19-24

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Biting reduces acute stress-induced oxidative stress in the rat hypothalamus2005

    • Author(s)
      S.Miyake, K.Sasaguri, N.Hori, H.Shoji, F.Yoshino, H.Miyazaki, K.Anzai, N.Ikota, T.Ozawa, M.Toyoda, S.Sato, M.Lee
    • Journal Title

      Redox Report 10(1)

      Pages: 19-24

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Reactive oxygen species scavenging ability of a new compound derived from weathered coal2004

    • Author(s)
      J.Ueda, N.Ikota, T.Shinoduka., T.Yamaguchi
    • Journal Title

      Spectrochimica Acta Part A, Molecular and Biomolecular Spectroscopy 60

      Pages: 2487-2492

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Reactive oxygen species scavenging ability of a new compound derived from weathered coal2004

    • Author(s)
      J.Ueda, N.Ikota, T.Shinoduka., T.Yamaguchi
    • Journal Title

      Spectrochimica Acta Part A, Molecular andBiomolecular Spectroscopy 60

      Pages: 2487-2492

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] EPR Study on Stable Magnesium Complexes of the Phenoxyl Radicals Derived from a Vitamin E Model and Its Deuterated Derivatives2004

    • Author(s)
      I.Nakanishi, S.Matsumoto, K.Ohkubo., K.Fukuhara., H.Okuda., K.Inami., M.Mochizuki., T.Ozawa, S.Itoh., S.Fukuzumi, N.Ikota
    • Journal Title

      Bulletin of the Chemical Society of Japan 77(9)

      Pages: 1741-1744

    • NAID

      10013584659

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] A Planar Catechin Analogue Having a More Negative Oxidation Potential than (+)-Catechin as an Electron-Transfer Antioxidant against a Peroxyl Radical2004

    • Author(s)
      I.Nakanishi, K.Ohkubo, K.Miyazaki, W.Hakamata, S.Urano, T.Ozawa, H.Okuda, S.Fukuzumi, N.Ikota, K.Fukuhara
    • Journal Title

      Chemical Research in Toxicology 17(1)

      Pages: 26-31

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Selective scavenging property of the indole moiety for the nitrating species of peroxynitrite2004

    • Author(s)
      H.Nakagawa, M.Takusagawa, H.Arima., K.Furukawa, T.Ozawa, N.Ikota, et al.
    • Journal Title

      Chemical & Pharmaceutical Bulletin 52(1)

      Pages: 146-149

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Ternary Complexes from Cu(II)-Oligopeptide and N-Acetyl-Histidine, as Studied by Circular Dichroism Spectroscopy2004

    • Author(s)
      A.Hanaki, J.Ueda, N.Ikota.
    • Journal Title

      Bulletin of the Chemical Society of Japan 77(8)

      Pages: 1475-1477

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Stability of the Cu(II) Complexes of Tripeptodes, Cu(H_2L), in Dynamic Aspects; L=Tripeptides Composed of Various Combinations of alpha-, beta-, and gamma-Amino Acid Residues. Stopped-flow Kinetic Studies on the Reaction of Cu(H_2L) with Cysteine2004

    • Author(s)
      A.Hanaki, J.Ueda, N.Ikota
    • Journal Title

      Bulletin of the Chemical Society of Japan 77

      Pages: 1639-1645

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] In Vivo Radioprotection of Mice by 3-Methyl-1-phenyl-2-pyrazolin-5-one(Edaravone; Radicut), a Clinical Drug2004

    • Author(s)
      K.Anzai, M.Furuse, A.Yoshida, A.Matsuyama, T.Moritake, K.Tsuboi., N.Ikota
    • Journal Title

      Journal of Radiation Research 45

      Pages: 319-323

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Stability of the Cu(II) Complexes of Tripeptodes, Cu(H-2L), in Dynamic Aspects ; L=Tripeptides Composed of Various Combinations of α-,β-,and γ-Amino Acid Residues. Stopped-flow Kinetic Studies on the Reaction of Cu(H_<-2> with Cystein2004

    • Author(s)
      A.Hanaki, J.Ueda, N.Ikota
    • Journal Title

      Bull.Chem.Soc.Jpn. 77

      Pages: 1639-1645

    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] N-[18F]fluoroethylpiperidin-4-ylmethyl butyrate : a novel radiotracer for quantifying brain butyrylcholinesterase activity by positron emission tomography2004

    • Author(s)
      T.Kikuchi, M.Zhang, N.Ikota, K.Fukushi, T.Okamura, K.Suzuki, Y.Arano, T.Irie
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters 14

      Pages: 1927-1930

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Assessment of oxidative Stress in the Spontaneously Hypertensive rat Brain Using Elevtron Spin Resonance(ESR) Imaging and in vivo L-Band ESR.2004

    • Author(s)
      M-C Lee, H.Shoji, K.Anzai, N.Ikota, T.Oawa, et al.
    • Journal Title

      Hypertens Res. 27

      Pages: 485-492

    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] EPR Study on Stable Magnesium Complexes of the Phenoxyl Radicals Derived from a Vitamin E Model and Its Deuterated Derivatives2004

    • Author(s)
      I.Nakanishi, S.Matsumoto, T.Ozawa, N.Ikota, et al.
    • Journal Title

      Bull.Chem.Soc.Jpn 77

      Pages: 1741-1744

    • NAID

      10013584659

    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Selective Scavenging Property of the Indole Moiety for the Nitrating Intermediate of Peroxynitrite.2004

    • Author(s)
      H.Nakagawa, M.Takusakawa, T.Ozawa, N.Ikota, et al.
    • Journal Title

      Chem.Pharm.Bull 52

      Pages: 146-149

    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] In Vivo Radioprotection of Mice by 3-Methyl-l- pheny1-2-pyrazolin-5-one(Edaravone; Radicut), a Clinical Drug2004

    • Author(s)
      K.Anzai, M.Furuse, A.Yoshida, A.Matsuyama, T.Moritake, K.Tsuboi., N.Ikota
    • Journal Title

      Journal of Radiation Research 45(2)

      Pages: 319-323

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Water-Accelerated Radical-Scavenging Reaction of (+)-Catechin in an Aprotic Medium2004

    • Author(s)
      I.Nakanishi, T.Kawashima, K.Fukuhara., H.Kanazawa., H.Okuda., S.Fukuzumi., T.Ozawa, N.Ikota
    • Journal Title

      ITE Letters on Batteries, New Technologies &Medicine 5(6)

      Pages: 585-588

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] ater-Accelerated Radical-Scavenging Reaction of(+)-Catechin in an Aprotic Medium.2004

    • Author(s)
      I.Nakanishi, T.Kawashima, K.Fukuhara, T.Ozawa, N.Ikota, et al.
    • Journal Title

      ITE Letters on Batteries, New Technologies & Medicine 5

      Pages: 585-588

    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] A Planar Catechin Analogue Having a More Negative Oxidation Potential than (+)-Catechin as an Electron-Transfer Antioxidant against a Peroxyl Radical2004

    • Author(s)
      I.Nakanishi, K.Ohkubo, K.Miyazaki, W.Hakamata, S.Urano, T.Ozawa, H.Okuda, S.Fukuzumi, N.Ikota, K.Fukuhara
    • Journal Title

      Chemical Research in Toxicology 17

      Pages: 26-31

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Reactive oxygen species scavenging ability of a new compound derived from weathered coal2004

    • Author(s)
      J.Ueda, N.Ikota, T.Shinozuka, T.Yamaguchi
    • Journal Title

      Spectrochimica Acta Part A 60

      Pages: 2487-249

    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] A Planar Catechin Analogue Having a More Negative Oxidation Potential than (+)-Catechin as an Electron-Transfer Antioxidant against a Peroxyl Radical.2004

    • Author(s)
      I.Nakanishi, T.Ozawa, S.Fukuzumi, N.Ikota, et al.
    • Journal Title

      Chem.Res.Toxicol 17

      Pages: 26-31

    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] EPR Study on Stable Magnesium Complexes of the Phenoxyl Radicals Derived from a Vitamin E Model and Its Deuterated Derivatives2004

    • Author(s)
      I.Nakanishi, S.Matsumoto, K.Ohkubo., K.Fukuhara., H.Okuda., K.Inami., M.Mochizuki., T.Ozawa, S.Itoh., S.Fukuzumi, N.Ikota
    • Journal Title

      Bulletin of the Chemical Society of Japan 77

      Pages: 1741-1744

    • NAID

      10013584659

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] In Vivpo Radioprotection of Mice by 3-methyl-1-phenyl-2-pyrazolin-5-one, a Brain-Protecting Medicine2004

    • Author(s)
      K.Anzai, A.Matsuyama, T.Moritake, N.Ikota, et al.
    • Journal Title

      J.Radiat.Res. 45

      Pages: 319-323

    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Selective scavenging property of the indole moiety for the nitrating species of peroxynitrite2004

    • Author(s)
      H.Nakagawa, M.Takusagawa, H.Arima., K.Furukawa, T.Ozawa, N.Ikota, et al.
    • Journal Title

      Chemical & Pharmaceutical Bulletin 52

      Pages: 146-149

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Ternary Complexes from Cu(II)-Oligopeptide and N-Acetyl-Histidine, as Studied by Circular Dichroism Spectroscopy2004

    • Author(s)
      A.Hanaki, J.Ueda, N.Ikota
    • Journal Title

      Bulletin of the Chemical Society of Japan 77

      Pages: 1475-1477

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Stability of the Cu(II) Complexes of Tripeptodes, Cu(H_2L), in Dynamic Aspects; L=Tripeptides Composed of Various Combinations of alpha-, beta-, and gamma-Amino Acid Residues. Stopped-flow Kinetic Studies on the Reaction of Cu(H 2L) with Cysteine,2004

    • Author(s)
      A.Hanaki, J.Ueda, N.Ikota
    • Journal Title

      Bulletin of the Chemical Society of Japan 77(9)

      Pages: 1639-1645

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Ternary Complexes from Cu(II)-Oligopeptide and N-Acetyl-L-Histidine, as Studied by Circular Dichroism Spectroscopy.2004

    • Author(s)
      A.Hanaki, J.Ueda, N.Ikota
    • Journal Title

      Bull.Chem.Soc.Jpn. 77

      Pages: 1475-1479

    • NAID

      10013451461

    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Water-Accelerated Radical-Scavenging Reaction of (+)-Catechin in an Aprotic Medium2004

    • Author(s)
      I.Nakanishi, T.Kawashima, K.Fukuhara., H.Kanazawa., H.Okuda., S.Fukuzumi., T.Ozawa, N.Ikota
    • Journal Title

      ITE Letters 5

      Pages: 585-588

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Journal Article] Dose and time dependence of radiation-induced nitric oxide formation in as quantified with electron paramagnetic resonance.2001

    • Author(s)
      H.Nakagawa, N.Ikota, T.Ozawat, Y.Kotake
    • Journal Title

      Nitric Oxide : Biology and Chemistry (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-11672222
  • [Journal Article] Induction of Superoxide in Glioma Cell Line U87 Stimulated with Lipopolysaccharide and Interferon Gamma : ESR Using a New Flow-type Quartz Cell.2001

    • Author(s)
      Hidehiko Nakagawa, Nobuo Ikota, et al.
    • Journal Title

      FEBS Lett. 471

      Pages: 753-765

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-11672222
  • [Journal Article] Synthesis of N-Methyl-3-(1-Hydroxy-5-[^<123>I]Iodopent-4-enyl)-4-Acetoxypiperidine, A Novel Candidate of Acetylcholinesterase Activity Imaging Agent2001

    • Author(s)
      Takao Ueda, Toshiaki Irie, Nobuo Ikota, et al.
    • Journal Title

      J.Labelled Cpd.Radiopharm. 43

      Pages: 753-765

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-11672222
  • [Journal Article] Dose and time dependence of radiation-induced nitric oxide formation in as quantified with electron paramagnetic resonance.2001

    • Author(s)
      H.Nakagawa, N.Ikota, T.Ozawat, Y.Kotake
    • Journal Title

      Nitric Oxide : Biology and Chemistry. 5

      Pages: 47-52

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11672222
  • [Journal Article] Synthesis of Piperidinyl and Pyrrolidinyl Butyrates for In Vivo measurement of Cerebral Butyrylcholinesterase Activity.2001

    • Author(s)
      Kikuchi, Tatsuya, Fukushi, Kiyoshi, Ikota, Nobuo, Ueda, Takao, Nagatsuka, Shin-ichiro, Arano, Yasushi, Irie, Toshiaki
    • Journal Title

      J Labelled Cpd.Radiopharm. 43

      Pages: 753-765

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11672222
  • [Journal Article] Synthesis of N-Methyl-3-(1-Hydroxy-5-[^<123>I]Iodopent-4-enyl)-4-Acetoxypiperidine, A Novel Candidate of Acetylcholinesterase Activity Imaging Agent.2000

    • Author(s)
      Takao Ueda, Toshiaki Irie, Kiyoshi Fukushi, Nobuo Ikota, Keizo Takatoku, Isamu Yomoda, Shin-ichiro Nagatsuka
    • Journal Title

      J Labelled Cpd.Radiopharm. 43

      Pages: 753-765

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11672222
  • [Journal Article] Induction of Superoxide in Glioma Cell Line U87 Stimulated with Lipopolysaccharide and Interferon Gamma : ESR Using a New Flow-type Quartz Cell.2000

    • Author(s)
      Hidehiko Nakagawa, Takashi Moritake, Koji Tsuboi, Nobuo Ikota, Toshihiko Ozawa
    • Journal Title

      FEBS Lett. 471

      Pages: 187-190

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11672222
  • [Journal Article] Scavengers for Peroxynitrite : Inhibition of Tyrosine Nitration and Oxidation with Tryptamine Derivatives, α-Lipoic Acid and Synthetic Compounds2000

    • Author(s)
      Nakagawa, H., Ikota, N., et al.
    • Journal Title

      Chem.Pharm.Bull. 48

      Pages: 261-265

    • NAID

      110003635439

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-11672222
  • [Journal Article] Scavengers for Peroxynitrite : Inhibition of Tyrosine Nitration and Oxidation with Tryptamine Derivatives, α-Lipoic Acid and Synthetic Compounds2000

    • Author(s)
      Hidehiko Nakagawa, Erika Sumiki, Mitsuko Takusagawa, Nobuo Ikota, Yoshikazu Matsushima, Toshihiko Ozawa
    • Journal Title

      Chem.Pharm.Bull. 48

      Pages: 261-265

    • NAID

      110003635439

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11672222
  • [Journal Article] A New Synthesis of All Four Stereoisomers of 2-(2,3-Dihydroxypropyl)piperidines via Iterative Asymmetric Dihydroxylation to Cause Enantiomeric Enhancement. Application to Asymmetric Synthesis of Naturally Occurring Piperidine Related Alkaloids.1999

    • Author(s)
      Hiroki Takahata, Minoru Kubota, Nobuo Ikota
    • Journal Title

      J Org.Chem. 64

      Pages: 8594-8601

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11672222
  • [Journal Article] Enogenous and New Synthetic Antioxidants for Peroxynitrite : selctive Inhibitory Effect of 5-Methoxytryptamine and α-Lipic Acid on Tyrosine Nitration by Peroxynitrite.1999

    • Author(s)
      Nakagawa, H., Ikota, N.et al.
    • Journal Title

      Antioxidants and Redox Signaling 1

      Pages: 239-244

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-11672222
  • [Journal Article] Endogenous and new Synthetic Antioxidants for Peroxynitrite : Selctive Inhibitory Effect of 5-Methoxytryptamine and Lipoic Acid on Tyrosine Nitration by Peroxynitrite.1999

    • Author(s)
      Nakagawa, H., Sumiki, E., Ikota, N., Matsushima, Y., Ozawa, T.
    • Journal Title

      Antioxidants and Redox Signaling 1

      Pages: 239-244

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11672222
  • [Journal Article] Isolation and Cloning of Rat Poly(ADP-ribose) Glycohydrolase : Presence of a Potential Nuclear Export Signal Conserved in Mammalian Orthologs.1999

    • Author(s)
      Takashi Shimokawa, Mitsuko Masutani, Shingo Nagasawa, Tadashige Nozaki, Nobuo lkota, Yoshiro Aoki, Hitoshi Nakagama, Takashi Sugimura.
    • Journal Title

      J Biochemistry 126

      Pages: 748-755

    • NAID

      10005858785

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11672222
  • [Journal Article] A New Synthesis of All Four Stereoisomers of 2-(2,3-Dihydroxypropyl)piperidines via Iterative Asymmetric Dihydroxylation to Cause Enantiomeric Enhancement. Application to Asymmetric Synthesis of Naturally Occurring Piperidine Related Alkaloids.1999

    • Author(s)
      Takahata, H., Kubota, M., Ikota, N.
    • Journal Title

      J.Org.Chem. 1

      Pages: 8594-8601

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-11672222
  • [Journal Article] Isolation and Cloning of Rat Poly(ADP-ribose) Glycohydrolase : Presence of a Potential Nuclear Export Signal Conserved in Mammalian Orthologs.1999

    • Author(s)
      Shimokawa T., Masutani, M., Ikota, N., Sugimura, T.et al.
    • Journal Title

      J.Biochemistry 128

      Pages: 748-755

    • NAID

      10005858785

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-11672222
  • [Patent] トコフェロールまたはトコトリエノール類のエステル誘導体を有効成分とする放射線防護剤2006

    • Inventor(s)
      安西 和紀, 上野 恵美, 薬丸 晴子, 上田順市, 明石 真言, 小林 静子, 高田 二郎, 伊古田 暢夫
    • Industrial Property Rights Holder
      放医研
    • Industrial Property Number
      2006-325408
    • Filing Date
      2006-12-01
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Patent] トコフェロールまたはトコトリエノール類のエステル誘導体を有効成分とする放射線防護剤2006

    • Inventor(s)
      安西 和紀, 上野 恵美, 薬丸 晴子, 上田 順市, 明石 真言, 小林 静子, 高田 二郎, 伊古田 暢夫
    • Industrial Property Rights Holder
      放医研
    • Industrial Property Number
      2006-325408
    • Filing Date
      2006-12-01
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Patent] 酵母を有効成分とする放射線防護剤2005

    • Inventor(s)
      安西 和紀, 上野 恵美, 薬丸 晴子, 乳井 美奈子, 中西 郁夫, 鍵谷 勤, 伊古田 暢夫
    • Industrial Property Rights Holder
      放医研
    • Industrial Property Number
      2005-379185
    • Filing Date
      2005-12-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590090
  • [Presentation] ブラジル産プロポリスに含まれるフェノール性抗酸化物質およびその誘導体のラジカル消去機構2009

    • Author(s)
      中西 郁夫、宇都 義浩、大久保 敬、川島 知憲、松本 謙一郎、Manda Sushma、堀 均、福原 潔、奥田 晴宏、伊古田暢夫、小澤俊彦、安西和紀
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2009-03-26
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Presentation] ラジカル消去活性の増強を目的としたビタミンE誘導体の開発2009

    • Author(s)
      稲見 圭子、中西 郁夫、大久保 敬、福原 潔、奥田 晴宏、伊古田 暢夫、福住 俊一、小澤 俊彦、安西 和紀、望月 正隆
    • Organizer
      第20回ビタミンE研究会
    • Place of Presentation
      奈良県文化会館(奈良県奈良市)
    • Year and Date
      2009-01-24
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Presentation] ブラジル産プロポリスに含まれるフェノール性抗酸化物質およびその誘導体のラジカル消去活性2008

    • Author(s)
      中西 郁夫、大久保 敬、宇都 義浩、川島 知憲、Manda Sushma、堀 均、福原 潔、奥田 晴宏、小澤 俊彦、伊古田 暢夫、福住 俊一、安西 和紀
    • Organizer
      第41回酸化反応討論会
    • Place of Presentation
      九州大学西新プラザ(福岡県福岡市)
    • Year and Date
      2008-11-27
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Presentation] 放射線防護剤を指向した分子内に塩基性部位を有する新規ビタミンE誘導体の開発2008

    • Author(s)
      中西 郁夫、乳井 美奈子、薬丸 晴子、大久保 敬、川島 知憲、福原 潔、奥田 晴宏、稲見 圭子、福住 俊一、伊古田 暢夫、小澤 俊彦、安西 和紀
    • Organizer
      日本環境変異原学会第37回大会(JEMS 2008)
    • Place of Presentation
      沖縄コンベンションセンター(沖縄県宜野湾市)
    • Year and Date
      2008-12-04
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Presentation] ミネラル酵母の放射線防護効果2008

    • Author(s)
      安西 和紀、伊古田 暢夫、上野 恵美、乳井 美奈子、鍵谷 勤
    • Organizer
      第2回日本放射線防護(生体防御)研究会
    • Place of Presentation
      京大会館(京都市)
    • Year and Date
      2008-06-01
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Presentation] 天然抗酸化物質の生合成前駆体およびその類縁体のラジカル消去活性2008

    • Author(s)
      中西 郁夫、宇都 義浩、大久保 敬、Manda Sushma、松本 謙一郎、永澤 秀子、堀 均、福原 潔、奥田 晴宏、伊古田 暢夫、福住 俊一、安西 和紀、小澤 俊彦
    • Organizer
      第8回AOB研究会
    • Place of Presentation
      御殿山ガーデン ホテルラフォーレ東京(東京都品川区)
    • Year and Date
      2008-06-13
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Presentation] アルテピリンCおよびその誘導体のラジカル消去反応における構造活性相関2008

    • Author(s)
      中西 郁夫、大久保 敬、宇都 義浩、川島 知憲、松本 謙一郎、Manda Sushma、堀 均、福原 潔、奥田 晴宏、伊古田 暢夫、福住 俊一、小澤 俊彦、安西 和紀
    • Organizer
      第47回電子スピンサイエンス学会年会
    • Place of Presentation
      九州大学医学部百年講堂(福岡県福岡市)
    • Year and Date
      2008-10-01
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Presentation] 骨髄に対する放射線防護剤、加熱処理亜鉛酵母の防護作用の解明-マウスモデルを用いたマイクロアレイ発現解析-2008

    • Author(s)
      上野 恵美、岩川 眞由美、今留 香織、今井 高志、明石 真言、伊古田 暢夫、安西 和紀
    • Organizer
      第38回放射線による制癌シンポジウムおよび第47回日本医学放射線学会生物部会学術大会
    • Place of Presentation
      ホテル日航高知旭ロイヤル(高知市)
    • Year and Date
      2008-06-20
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Presentation] One-Step Hydrogen Atom Transfer in Radical-Scavenging Reactions by Artepillin C Derivatives Enhanced by Electron-Donating Groups2008

    • Author(s)
      Ikuo Nakanishi, Kei Ohkubo, Yoshihiro Uto, Tomonori Kawashima, Sushma Manda, Kiyoshi Fukuhara, Haruhiro Okuda, Hitoshi Hori, Nobuo Ikota, Shunichi Fukuzumi, Toshihiko Ozawa, Kazunori Anzai
    • Organizer
      15th Annual Meeting of the Society for Free Radical Biology and Medicine (SFRBM)
    • Place of Presentation
      Indianapolis Marriott Downtown
    • Year and Date
      2008-11-19
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Presentation] γ-TDMGによる被曝マウスの骨髄死抑制2008

    • Author(s)
      安西 和紀、上野 恵美、伊古田 暢夫、高田 二郎
    • Organizer
      第2回日本放射線防護(生体防御)研究会
    • Place of Presentation
      京大会館(京都市)
    • Year and Date
      2008-06-01
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Presentation] プロトン共役電子移動を経由するレスベラトロールのラジカル消去反応2008

    • Author(s)
      中西 郁夫、島田 知一、大久保 敬、Manda Sushma、清水健彦、浦野四郎、奥田晴宏、宮田直樹、小澤俊彦、安西和紀、福住俊一、伊古田暢夫、福原潔
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市
    • Year and Date
      2008-03-26
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Presentation] 天然フェノール性抗酸化物質を基本骨格にした新規抗酸化物質の開発2007

    • Author(s)
      中西 郁夫、大久保 敬、宇都 義浩、川島 知憲、Manda Sushma、福原 潔、奥田 晴宏、堀 均、伊古田暢夫、福住 俊一、安西 和紀、小澤 俊彦
    • Organizer
      第7回AOB研究会
    • Place of Presentation
      台大醫院國際會議中心(台北市)
    • Year and Date
      2007-06-01
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Presentation] X線照射後腹腔内投与でマウス骨髄死を防護するミネラル含有酵母2007

    • Author(s)
      安西 和紀、上野 恵美、乳井 美奈子、薬丸 晴子、中西 郁夫、上田 順市、伊古田 暢夫、鍵谷 勤
    • Organizer
      第1回日本放射線防護研究会
    • Place of Presentation
      京大会館(京都)
    • Year and Date
      2007-05-20
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Presentation] 抗酸化成分レスベラトロールのラジカル消去活性の増強と遺伝毒性の軽減2007

    • Author(s)
      福原 潔、中西 郁夫、小澤 俊彦、伊古田 暢夫、宮田 直樹、奥田 晴宏
    • Organizer
      第40回酸化反応討論会
    • Place of Presentation
      奈良女子大学文学部南棟2階218教室(奈良県奈良市)
    • Year and Date
      2007-11-17
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Presentation] 分子内にリジン部位を有する平面型カテキン誘導体のラジカル消去反応2007

    • Author(s)
      福原 潔、中西 郁夫、小原 美紀、大久保 敬、川島 知憲、小澤 俊彦、伊古田 暢夫、安西 和紀、福住 俊一、宮田 直樹、斎藤 慎一、奥田 晴宏
    • Organizer
      第22回生体機能関連化学シンポジウム
    • Place of Presentation
      東北大学多元物質科学研究所(宮城県仙台市)
    • Year and Date
      2007-09-28
    • Data Source
      KAKENHI-PROJECT-19590113
  • [Presentation] X線によるマウス骨髄死およびラット乳腺腫瘍発生対する水溶性ビタミンE誘導tocopherol monoglucoside(TMG)の防護効果2007

    • Author(s)
      安西 和紀、上野 恵美、稲野 宏志、小野田 眞、伊古田 暢夫、鍵谷 勤
    • Organizer
      第1回日本放射線防護研究会
    • Place of Presentation
      京大会館(京都)
    • Year and Date
      2007-05-20
    • Data Source
      KAKENHI-PROJECT-19590113
  • 1.  NAKANISHI Ikuo (70356137)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 50 results
  • 2.  SUZUKI Toshinori (90368697)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  NAKAGAWA Hidehiko (80281674)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 4.  TAKESHITA Keizo (70175438)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  ANZAI Kazunori (70128643)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  MASUMIZU Toshiki (30412737)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  OKAZAKI Shoko (40435152)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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