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OGAWA Tomohiko  小川 知彦

ORCIDConnect your ORCID iD *help
Researcher Number 80160761
Other IDs
Affiliation (based on the past Project Information) *help 2007: 朝日大, 歯学部, 教授
1998 – 2006: Asahi University, School of Dentistry, Department of Oral Microbiology, Professor, 歯学部, 教授
1991 – 1997: Department of Oral Microbiology, Osaka University Faculty of Dentistry, 歯学部, 助教授
1990: 大阪大学, 歯学部, 講師
1986 – 1990: 大阪大学, 歯学部, 助手
Review Section/Research Field
Principal Investigator
Morphological basic dentistry / Pathobiological dentistry/Dental radiology / Biological Sciences
Except Principal Investigator
小児・社会系歯学 / Conservative dentistry / Surgical dentistry / Periodontal dentistry / Functional basic dentistry / 細菌学
Keywords
Principal Investigator
Porphyromonas gingivalis / 歯周病 / 線毛 / サイトカイン / Cytokine / Immunobiological activity / リピドA / 合成ペプチド / Treponema medium / Endotoxic property … More / LPS / Helicobacter pylori / Periodontal disease / Toll様受容体 / 歯肉上皮細胞 / 内毒素 / 炎症性サイトカイン / Toll-like receptor / Human gingival eptithelial cell / Outer membrane / Oral treponema / ヒト歯肉上皮細胞 / 菌体表層タンパク質 / 複合糖質画分 / 細胞応答 / 菌体成分 / 口腔スピロヘータ / Chemical structure / Glycolipid / Porphyromonas gingiuvalis / 内毒素活性 / リポ多糖体 / 口腔トレポネーマ / compound 506 / lipid A / Helicobacter phyori / 免疫生物学的作用 / 慢性胃炎 / Paper point / Antibody / Diagnosis / Serum / Epitope of B cell / Fimbriae / ペ-パ-ポイント / 抗体 / 診断 / 血清 / B細胞エピトープ / Porphyromanas gingivalis / エピトープ / 化学合成 / ワクチン / リポペプチド / 歯垢 / 病原因子 / 病原因子関連分子パターン / リポタンパク質 / Porphyromonas ginigvalis / リスク因子 / 唾液 / ダイオキシン / 細胞内情報伝達 / ヒト単核球細胞 / ヘルパーT細胞 / T細胞エピトープ / 化学走化性 / マクロファージ / 単球 / Pophyromonas gingivalis / 赤血球 / 免疫応答 / ELISPOT / ELISA / 抗体産生細胞 / 免疫グロブリン … More
Except Principal Investigator
Streptococcus mutans / Periodontal disease / 歯周病 / IgG / Bacteroides gingivalis / ラテックス凝集反応 / う蝕 / Fimbriae / 抗体 / サイトカイン / 線毛 / クラス / 免疫応答 / 抗体産生細胞 / 線毛タンパク / Bacteroides / Antibody / Latex agglutination / ポリクロナール抗体 / モノクロナール抗体 / ラテックス凝集法 / LPS / Ltex beads / Monoclonal antibodies / Dental caties / 抗原抗体反応 / 凝集反応 / 診断キット / S.mutans / モノクローン抗体 / cytokine / endotoxemia / keratinocyte / lipopolysaccharide / cutaneous wound healing / RT-PCR / 遺伝子発現 / エンドトキシン血症 / 表皮角化細胞 / 内毒素性リポ多糖 / 創傷治癒 / 16 sRNA gene / Quantitative PCR / Plaque microflora / Immunological profile / Cytokine genes / Host-parasite interaction / 遺伝子プロファイル / 16 sRNA遺伝子 / 16sRNA遺伝子 / 定量的PCR / プラーク細菌叢 / 免疫学的プロファイル / サイトカイン遺伝子 / 宿主-細菌相互作用 / Egg yolk antibody / Dental caries / Oral passive immunization / Glucosyltransferase / 受動免疫 / Stroptococcus mutans / 卵黄抗体 / 経口受動免疫 / グルコシルトランスフェラ-ゼ / Adjuvant / Cytokine / Local Immunity / Immunoglobulin / Porphyromanas gingivalis / 菌体成分 / Hー2ハプロタイプ / サブクラス / ELISPOT / ELISA / アジュバント / 局所免疫 / 免疫グロブリン / Porphyromonas gingivalis / Administration route / Periodontopathic bacteria / Gingival tissues / Immune response / Antibody-secreting cells / Immunoglobulin classes / Fimbrial protein / 投与経路 / 歯周病原性細菌 / 歯肉組織 / 免疫グロブリンクラス / インターロイキシ6 / インターフェロン / 腫瘍壊死因子 / BRM / ムラミルペプチド / リピドA / 内毒素 Less
  • Research Projects

    (20 results)
  • Co-Researchers

    (24 People)
  •  TLRリガンドを結合した歯周病感染防御ペプチドワクチンの創出Principal Investigator

    • Principal Investigator
      小川 知彦
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Asahi University
  •  歯周病原細菌由来の新しい病原関連分子パターンの構造学的・免疫分子生物学的研究Principal Investigator

    • Principal Investigator
      小川 知彦
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Asahi University
  •  歯周病リスク因子としての唾液蓄積ダイオキシン類の解析Principal Investigator

    • Principal Investigator
      小川 知彦
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Asahi University
  •  Molecular biological properties of oral treponemes and their outer membrane extractsPrincipal Investigator

    • Principal Investigator
      OGAWA Tomohiko
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Asahi University
  •  Development of a new diagnostic strategy of periodontal disease based on the gene profile associated with host defense mechanisms.

    • Principal Investigator
      SHIMAUCHI Hidetoshi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Periodontal dentistry
    • Research Institution
      TOHOKU UNIVERSITY
  •  Molecular biological analysis for regenerated epithelial tissues on cutaneous wound healing process

    • Principal Investigator
      TAKAI Yoshiaki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Asahi University
  •  Chemical analysis and immunobiological activities of lipid A molecules derived from oral spirochetePrincipal Investigator

    • Principal Investigator
      OGAWA Tomohiko
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Asahi University
  •  Molecular biological properties of lipidA derived from chronic inflammatory pathogensPrincipal Investigator

    • Principal Investigator
      OGAWA Tomohiko
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Asahi University
      Osaka University
  •  歯周病原性細菌由来リピドAのヒト単核球細胞活性化による細胞内情報伝達機構の解析Principal Investigator

    • Principal Investigator
      小川 知彦
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Osaka University
  •  歯周病原性細菌線毛のヘルパーT細胞活性化機構に関する免疫分子生物学的研究Principal Investigator

    • Principal Investigator
      小川 知彦
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Osaka University
  •  Development of diagnostic system in periodontal disease using synthetic peptides containing epitopes of surface protein of periodontopathic bacteriaPrincipal Investigator

    • Principal Investigator
      OGAWA Tomohiko
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Osaka University
  •  歯周病の感染・発症機構の解明に関する免疫分子生物学的研究Principal Investigator

    • Principal Investigator
      小川 知彦
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Osaka University
  •  歯周病の感染機構の解明に関する免疫分子生物学的研究Principal Investigator

    • Principal Investigator
      小川 知彦
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Osaka University
  •  歯周病原菌染防御システムに関する免疫分子生物学的研究Principal Investigator

    • Principal Investigator
      小川 知彦
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Osaka University
  •  Immunobiological Studies on the Pathogenic Mechanisms of Periodontal Disease

    • Principal Investigator
      HAMADA Shigeyuki
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University Faculty of Dentistry
  •  Studies on the pathogenesis of periodontal disease from the viewpoint of local immunity

    • Principal Investigator
      HAMADA Shigeyuki
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Osaka University
  •  Development of Passive Immunization System Against Dental Caries by Hen Egg Yolk Antibodies of Streptococcus Mutans.

    • Principal Investigator
      OOSHIMA Takashi
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B).
    • Research Field
      小児・社会系歯学
    • Research Institution
      Osaka University Faculty of Dentistry
  •  合成ムラミルペプチドによる低毒性リピドA類縁体の生体反応調節(BRM)作用の増強

    • Principal Investigator
      TAKADA Haruhiko
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      細菌学
    • Research Institution
      Osaka University
  •  DEVELOPMENT OF LATEX AGGLUTINATION TEST FOR SPECIFIC DETECTION OF BACTEROIDES GINGIVALIS

    • Principal Investigator
      HAMADA Shigeyuki
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Conservative dentistry
    • Research Institution
      OSAKA UNIVERSITY
  •  Rapid Method for Identification of S. mutans from Human Clinical Specimens Using Monospecific Antibodies

    • Principal Investigator
      HAMADA Shigeyyki
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      小児・社会系歯学
    • Research Institution
      Osaka University
  • 1.  TAKADA Haruhiko (30135743)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  HAMADA Shigeyuki (60028777)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  ASAI Yasuyuki (30329487)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  MORISAKI Ichijiro (30116115)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  SUDA Yasuo (70179282)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  玉井 利代子 (90367566)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  OOSHIMA Takashi (80116003)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  IZUMITANI Akira (70168277)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  UMEMOTO Tohihiko (80076033)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  HASHIMOTO Masahito (30333537)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  SHIMAUCHI Hidetoshi (70187425)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  IKAWA Motohide (80176065)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  IIYAMA Masao (00193152)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  NEMOTO Eiji (40292221)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  TAKAI Yoshiaki (70197044)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  SAITOH Masanori (30308663)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  KOGA Thoshihiko (10037541)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  KIMURA Shigenobu (10177917)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  牧村 裕 (00387474)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  向井 徹 (50209970)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  山本 浩代 (50329497)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  KIYONO Hiroshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  MCGHEE Jerry R.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  三原 丞二
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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