OUCHI Yasuyoshi 大内尉義

… Alternative Names

大内尉義オオウチヤスヨシ

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Researcher Number	80168864
External Links
Affiliation (based on the past Project Information) *help	2007 – 2010: 東京大学, 医学部附属病院, 教授 2008: 東京大学, 医学部・附属病院, 教授 2002 – 2005: 東京大学, 医学部附属病院, 教授 2003: 東京大学, 大学院・医科系研究科, 教授 2002 – 2003: 東京大学, 大学院・医学系研究科, 教授 … More 2000 – 2001: 東京大学, 医学部・附属病院, 教授 1999: 東京大学, 医学部・付属病院, 教授 1996 – 1997: 東京大学, 医学部・附属病院, 教授 1995: 東京大学, 医学部(病), 教授 1992 – 1994: 東京大学, 医学部(病), 講師 1991: 東京大学, 医学部・(病), 講師 1989: 東京大学, 医学部(病), 講師 1988: 東京大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Circulatory organs internal medicine / General internal medicine (including Psychosomatic medicine) Except Principal Investigator Circulatory organs internal medicine / Circulatory organs internal medicine / Medical sociology / 基礎・地域看護学 / 内分泌・代謝学
Keywords	Principal Investigator 血管平滑筋細胞 / 動脈硬化 / DNA chip / 血管内皮細胞 / Gas6 / adeno virus vector / vascular smooth muscle cells / estrogen receptor / アポトーシス / エストロゲン受容体 … More / 副甲状腺ホルモン関連ペプチド / カルシトニン遺伝子関連ペプチド / 細胞内カルシウム / apoptosis / Na-dependent Pi cotransporter / human aortic smooth muscle cells / vascular calcification / 糖尿病 / ヒト大動脈由来血管平滑筋細胞 / AGE / デキサメサゾン / VitD3 / 石灰化 / ビスフォスフォネート / GAS / 平滑筋細胞石灰化 / スタチン / Na依存性リン共輸送体 / 血管石灰化 / 骨量 / トランジェニックラット / 卵巣摘除 / マイクロアレイ / ERβ / ERα / ラロキシフェン / エストロゲン / DNAチップ / アデノウィルスベクター / 増殖 / 平滑筋細胞 / 内皮細胞 / アデノウイルスベクター / トランスジェニック・ラット / 血圧日内変動 / 本態性高血圧症 / 自然発症高血圧ラット / 血圧 / カルシウム / 長寿遺伝子 / 老年症候群 / 性差 / 性ホルモン / 女性外来 / 健康寿命延長 / 生体システム / ニューラルネットワーク / 生体信号解析 / 数理モデル / 分子生物学 / ゆらぎ / 循環調節 / ホメオスタシス / 神経細胞死 / ApolipoproteinE受容体 / ApolipoproteinEイソ蛋白 / ApolipoproteinE / 内皮機能 / 血圧動揺性 / サイトカイン / 細胞内Ca^<++>濃度 / 電位依存性カルシウムチャンネル / Zuckerラット / 細胞内カルシウム濃度 / インスリン抵抗性 / インスリン / 交感神経 / Pclymerase chain reaction / サイクリックAMP / 成長因子 / 脳動脈 / 冠動脈 … More Except Principal Investigator Sirt1 / Sir2 / 高齢者 / 退院支援 / 一酸化窒素 / 血管内皮細胞 / 血管平滑筋細胞 / endothelial dysfunction / atherosclerosis / cardiovascular disease / aging / senescence / 酸化ストレス / 細胞増殖 / 内皮機能障害 / 動脈硬化 / 心血管疾患 / エイジング / 老化 / the elder inpatients / discharge planning / 機能評価 / Nurse / Support skill / Follow-up / Long-Term Care Insurance / National Survey / Elderly / Discharge Planning / 在院日数 / フォローアップ / 看護師 / 支援技術 / フォロアップ / 介護保険 / 全国調査 / dedifferentiation / transcription / vascular smooth muscle cells / neointima / vasodilatation / nitric oxide / vascular endothelial cells / arteriosclerosis / 脱分化 / 転写調節 / 新生内膜 / 血管拡張 / 動脈硬化症 / Gas6-Axl経路 / Gas6-x1 / 細胞アポトーシス / Gas6-Axl / アポトーシス / 高リン血症 / 血管石灰化 / スカベンジャー受容体 / マクロファージの泡沫化 / フォリスタチン / アクチビン / 内皮依存性血管拡張反応 / C-fos / エンドセリン / 大動脈 / エストロゲン受容体 / エストロゲン / 分子生物学 / 骨粗鬆症 / 破骨細胞 / 骨芽細胞 / アンドロゲンレセプター / エストロゲンレセプター / 性ホルモン Less

Investigation for the establishment of gender-sensitive geriatric medicinePrincipal Investigator
- Principal Investigator
  
  OUCHI Yasuyoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  The University of Tokyo
Vascular calcification by restoring Gas6-Axl survival pathway
- Principal Investigator
  
  IIJIMA Katsuya
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
The Role of Sirtl in Vascular Senescence and Funcrion
- Principal Investigator
  
  AKISHITA Masahiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
Molecular mechanisms and novel therapeutic approaches for cardiovascular calcificationPrincipal Investigator
- Principal Investigator
  
  OUCHI Yasuyoshi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
Comparison of discharge planning for the elder inpatients in the medical institutions where functions differ.
- Principal Investigator
  
  NAGANO Koichiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical sociology
- Research Institution
  The University of Tokyo
Research on the effectiveness of discharge planning program for aged inpatients
- Principal Investigator
  
  MURASHIMA Sachiyo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  基礎・地域看護学
- Research Institution
  The University of Tokyo
Investigation and clinical application to the prevention of estrogen receptor α and β prevent vascular disease.Principal Investigator
- Principal Investigator
  
  OUCHI Yasuyoshi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
Role of asymmetric dimethylarginine (ADMA) and its hydrolases (DDAH I and II) in atnerogenesis
- Principal Investigator
  
  YOSHIZUMI Masao
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
Investigation and clinical application of estrogen receptor α and β prevent vascular diseasePrincipal Investigator
- Principal Investigator
  
  OUCHI Yasuyoshi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
神経細胞死とアポリポ蛋白受容体についてPrincipal Investigator
- Principal Investigator
  
  大内尉義
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
循環系のホメオスタシスとその異常の基本原理に関する新しい統合的アプローチPrincipal Investigator
- Principal Investigator
  
  大内尉義
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
血管内皮細胞機能に及ぼす血圧日内変動の影響Principal Investigator
- Principal Investigator
  
  大内尉義
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
アクチビン/フォリスタチンの動脈硬化進展にかかる機序に関する研究
- Principal Investigator
  
  KOZAKI Koichi
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
血管機能調節機構におけるエストロゲンおよびエストロゲン受容体の役割
- Principal Investigator
  
  AKISHITA Masahiro
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
新しい内皮由来血管拡張因子としての副甲状腺ホルモン関連ペプチドPrincipal Investigator
- Principal Investigator
  
  大内尉義
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
血管組織における副甲状腺ホルモン関連ペプチドの発現-動脈硬化の発症、進展におけるその意義Principal Investigator
- Principal Investigator
  
  大内尉義
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
性ホルモン受容体の発現調節と機能からみた骨粗鬆症の成因に関する分子生物学研究
- Principal Investigator
  
  折茂肇
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  The University of Tokyo
インスリン抵抗性と高血圧に関する実験的研究-血管平滑筋Caチャンネル異常の検討Principal Investigator
- Principal Investigator
  
  大内尉義
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
心血管系組織におけるカルシトニン遺伝子関連ペプチドの発現ーー病態との関連Principal Investigator
- Principal Investigator
  
  大内尉義
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
動脈硬化の発症抑制因子としてのカルシトニン遺伝子関連ペプチドに関する研究Principal Investigator
- Principal Investigator
  
  大内尉義
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
血管壁細胞機能の部位特異性に関する研究Principal Investigator
- Principal Investigator
  
  大内尉義
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
カルシウム摂取と高血圧の研究Principal Investigator
- Principal Investigator
  
  大内尉義
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo

All 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book

[Book] 新老年学第3版2010
- Author(s)
  大内尉義, 秋山弘子, 折茂肇編
- Total Pages
  2142
- Publisher
  東京大学出版会・東京
- Data Source
  KAKENHI-PROJECT-20249041
[Book] 新老年学第3版2010
- Author(s)
  大内尉義,秋山弘子,折茂肇編
- Publisher
  東京大学出版会・東京
- Data Source
  KAKENHI-PROJECT-20249041
[Book] 性差とは何か:ジェンダー研究と生物学の対話2008
- Author(s)
  大内尉義、他
- Total Pages
  311
- Publisher
  日本学術協力財団編
- Data Source
  KAKENHI-PROJECT-20249041
[Book] 性差医療の考え方と課題性差とは何か-ジェンダー研究と生物学との対話2008
- Author(s)
  大内尉義、日本学術協力財団編
- Publisher
  日本学術協力財団・東京
- Data Source
  KAKENHI-PROJECT-20249041
[Book] 改訂高齢女性の健康増進のためのホルモン補充療法ガイドライン(武谷雄二、大内尉義/編)2004
- Author(s)
  大内尉義, 他
- Total Pages
  326
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Induction of Endothelial Nitric Oxide Synthase, SIRT 1, and Catalase by Statins Inhibits Endothelial Senescence Through the Akt Pathway.2011
- Author(s)
  Ota H, Eto M, Kano MR, Kahyo T, Setou M, Ogawa S, Iljima K, AkishitaM, Ouchi Y.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: in press(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] Induction of endothelial nitric oxide synthase, SIRT1, and catalase by statins inhibits endothelial senescence through the Akt pathway2010
- Author(s)
  Ota H, Eto M, Kano MR, Kahyo T, Setou M, Ogawa S, Iijima K, Akishita M, Ouchi Y
- Journal Title
  
  Arterioscler Thromb Vasc Biol. 30
  
  Pages: 2205-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] Visceral fat accumulation and metabolic risk factor clustering in older adults2010
- Author(s)
  Nomura K, Eto M, Kojima T, Ogawa S, Iijima K, Nakamura T, Araki A, Akishita M, Ouchi Y
- Journal Title
  
  J Am Geriatr Soc. 58
  
  Pages: 1658-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] Aortic arch calcification detectable on chest X-ray is a strong independent predictor of cardiovascular events beyond traditional risk factors2010
- Author(s)
  Iijima K, Hashimoto H, Hashimoto M, Son BK, Ota H, Ogawa S, Eto M, Akishita M, Ouchi Y
- Journal Title
  
  Atherosclerosis 210
  
  Pages: 137-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] Androgen receptor-dependent activation of endothelial nitric oxide synthase in vascular endothelial cells : role of phosphatidylinositol 3-kinase/akt pathway.2010
- Author(s)
  Yu J, Akishita M, Eto M, Ogawa S, Son BK, Kato S, Ouchi Y, Okabe T.
- Journal Title
  
  Endocrinology 151
  
  Pages: 1822-1828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] Androgen receptor-dependent activation of endothelial nitric oxide synthase in vascular endothelial cells: Role of PI3-kinase/Akt pathway2010
- Author(s)
  Yu J, Akishita M, Eto M, Ogawa S, Son BK, Kato S, Ouchi Y, Okabe T
- Journal Title
  
  Endocrinology 151
  
  Pages: 1822-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] Plasma sex hormone levels and mortality in disabled older men and women2010
- Author(s)
  Fukai S, Akishita M, Yamada S, Ogawa S, Yamaguchi K, Kozaki K, Toba K, Ouchi Y
- Journal Title
  
  Geriatr Gerontol Int. (Epub ahead of print)
- NAID
  10029333495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] Association of low testosterone with metabolic syndrome and its components in middle-aged Japanese men2010
- Author(s)
  Akishita M, Fukai S, Hashimoto M, Kameyama Y, Nomura K, Nakamura T, Ogawa S, Iijima K, Eto M, Ouchi Y
- Journal Title
  
  Hypertens Res 33
  
  Pages: 587-91
- NAID
  10026397148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] Androgen receptor-dependent transactivation of growth arrest-specific gene 6 mediates inhibitory effects of testosterone on vascular calcification2010
- Author(s)
  Son BK, Akishita M, Iijima K, Ogawa S, Maemura K, Yu J, Takeyama K, Kato S, Eto M, Ouchi Y
- Journal Title
  
  J Biol Chem 285
  
  Pages: 7537-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] Visceral fat accumulation and metabolic risk factor clustering in older adults.2010
- Author(s)
  Nomura K, Eto_M, Kojima T, Ogawa S, Iljima K, Nakamura T, Araki A, Akishita M, Ouchi Y.
- Journal Title
  
  JAm Geriatr Soc.
  
  Volume: 58 Pages: 1658-1663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] Effects of testosterone in older men with mild to moderate cognitiveiunpaument2010
- Author(s)
  Fukai S, Akishita M, Yamada S, Toba K, Ouchi Y.
- Journal Title
  
  JAm Geriatr Soc.
  
  Volume: 158 Pages: 1419-1421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] Low testosterone level as a predictor of cardiovascular events in Japanese men with coronary risk factors2010
- Author(s)
  Akishita M, Hashimoto M, Ohike Y, Ogawa S, Iijima K, Eto M, Ouchi Y
- Journal Title
  
  Atherosclerosis 210
  
  Pages: 232-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] Validity and usefulness of aortic arch calcification in chest X-ray2009
- Author(s)
  Hashimoto H, Iijima K, Hashimoto M, Son BK, Ota H, Ogawa S, Eto M, Akishita M, Ouchi Y
- Journal Title
  
  J Atheroscler Thromb. 16
  
  Pages: 256-64
- NAID
  10025765733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] Association of plasma sex hormone levels with functional decline in elderly men and women2009
- Author(s)
  Fukai S, Akishita M, Yamada S, Hama T, Ogawa S, Iijima K, Eto M, Kozaki K, Toba K, Ouchi Y
- Journal Title
  
  Geriatr Gerontol Int. 9
  
  Pages: 282-9
- NAID
  10025637981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] A selective estrogen receptor modulator inhibits TNF-alpna-mcluced apoptosis by activating ERK1/2 signaling pathway in vascular endothelial cells.2009
- Author(s)
  Yu J, Eto M, Akishita M, Okabe T, Ouchi Y.
- Journal Title
  
  Vascul Pharmacol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] Sirolimus and Everolimus Induce Endothelial Cellular Senescence via Sirt1 Downregulation: Therapeutic Implication of Cilostazol after Drug-eluting Stent Implantation.2009
- Author(s)
  Ota H, Eto M, Ako J, Ogawa S, Iijima K, Akishita M, Ouchi Y.
- Journal Title
  
  J Am Coll Cardiol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] A selective estrogen receptor modulator inhibits TNF-alpha-induced apoptosis by activating ERK1/2 signaling pathway in vascular endothelial cells.2009
- Author(s)
  Yu J, Eto M, Akishita M, Okabe T, Ouchi Y.
- Journal Title
  
  Vascul Pharmacol 51
  
  Pages: 21-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] Validity and usefulness of aorticarch calcification in chest X-ray2009
- Author(s)
  Hashimoto H, Iijima K, Hashimoto M, SonBK, Ota H, Ogawa S, Eto M, Akishita M, Ouchi Y.
- Journal Title
  
  J Atheroscler Thromb (in press)
- NAID
  10025765733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590854
[Journal Article] Sirolimus and Everolimus Induce Endothelial Cellular Senescence via Sirtl Downregulation : Therapeutic Implication of Cilostazol after Drug-eluting Stent Implantation.2009
- Author(s)
  Ota H, Eto M, Ako J, Ogawa S, Iijima K, Akishita M, Ouchi Y.
- Journal Title
  
  J Am Coll Cardiol 53
  
  Pages: 2298-2305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] Sirolimus and everolimus induce endothelial cellular senescence via sirtuin 1 down-regulation : therapeutic implication of cilostazol after drug-eluting stent implantation2009
- Author(s)
  Ota H, Eto M, Ako J, Ogawa S, Iijima K, Akishita M, Ouchi Y
- Journal Title
  
  J Am Coll Cardiol. 53
  
  Pages: 2298-305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] Raloxifene analogue LY117018 suppresses oxidative stress-induced endothelial cell apoptosis through activation of ERK 1/2 signaling pathway.2008
- Author(s)
  Yu J, Eto M, Kozaki K, Akishita M, Okabe T, Ouchi Y.
- Journal Title
  
  Eur J Pharmacol (掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590801
[Journal Article] Cilostazol inhibitsoxidative stress-induced premature senescencevia upregulation of Sirt1 in human endothelialcells2008
- Author(s)
  Ota H, Eto M, Kano MR, Ogawa S, Iijima K,Akishita M, Ouchi Y.
- Journal Title
  
  Arterioscler Thromb Vasc Biol 28(9)
  
  Pages: 1634-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590854
[Journal Article] Cilostazol inhibits oxidative stress-induced premature senescence via upregulation of Sirt1 in human endothelial cells2008
- Author(s)
  Ota H, Eto M, Kano MR, Ogawa S, Iijima K, Akishita M, Ouchi Y
- Journal Title
  
  Arterioscler Thromb Vasc Biol. 28
  
  Pages: 1634-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] Mechanism of Pi-Induced vasacular calcificatin.2008
- Author(s)
  Son BK, Akishita M, lijima K, Eto M, Ouchi Y.
- Journal Title
  
  J Atheroscler Thromb. (掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590854
[Journal Article] Association of plasma dehydroepiandrosterone-sulfate levels with endothelial function in postmenopausal women with coronary risk factors.2008
- Author(s)
  Akishita M, Ogawa S, lijima K, Eto M, Ouchi Y, et. al.
- Journal Title
  
  Hypertens Res. (掲載確定)
- NAID
  10021261147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590801
[Journal Article] Adiponectin antagonizes stimulatory effect of TNF{alpha} on vascular smooth muscle cell calcification: Regulation of Gas6-mediated survival pathway by AMP-activated protein kinase.2008
- Author(s)
  Son BK,Akishita M,lijima K,Kozaki K, Maemura K,Eto M,Ouchi Y.
- Journal Title
  
  Endocrinology. 149
  
  Pages: 1646-1653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590854
[Journal Article] Nocturia in elderly people withhypertension--no influence of low-dosethiazide added to losartan2008
- Author(s)
  Kojima T, Akishita M, Iijima K, Eto M, Ouchi Y.
- Journal Title
  
  J Am Geriatr Soc 56(11)
  
  Pages: 2155-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590854
[Journal Article] Mechanism of Pi-induced Vascular Calcification.2008
- Author(s)
  Son BK,Akishita M,lijima K, Eto M,Ouchi Y.
- Journal Title
  
  J Atheroscler Thromb. 15
  
  Pages: 63-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590854
[Journal Article] Validity and usefulness of aortic arch calcification in chest X-ray.2008
- Author(s)
  Hashimoto H, Iijima K, Hashimoto M, Son BK, Ota H, Ogawa S, Eto M, Akishita M, Ouchi Y.
- Journal Title
  
  J Atheroscler Thromb. (in press)
- NAID
  10025765733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590854
[Journal Article] Mechanism of pi-induced vascularcal cification2008
- Author(s)
  Son BK, Akishita M, Iijima K, Eto M, Ouchi Y.
- Journal Title
  
  J Atheroscler Thromb 15(2)
  
  Pages: 63-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590854
[Journal Article] Adiponectin antagonizes stimulatory effect of TNF {alpha} on vascular smooth muscle cell calcification: Regulation of Gas6-mediated survival pathway by AMP-activated protein kinase.2008
- Author(s)
  Son BK, Akishita M, lijima K, Kozaki K, Maemura K, Eto M, Ouchi Y.
- Journal Title
  
  Endocrinology. 149
  
  Pages: 1646-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590854
[Journal Article] Cilostazol inhibits oxidative stress-induced premature senescence via upregulation of Sirtl in human endothelial cells.2008
- Author(s)
  Ota H, Eto M, Kano MR, Ogawa S, lijima K, Akishita M, Ouchi Y.
- Journal Title
  
  Arterioscler Thromb Vasc Biol. 28
  
  Pages: 1634-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249041
[Journal Article] Adiponectinantagonizes stimulatory effect of tumornecrosis factor-alpha on vascular smoothmuscle cell calcification2008
- Author(s)
  Son BK, Akishita M, Iijima K, Kozaki K,Maemura K, Eto M, Ouchi Y.
- Journal Title
  
  regulation of growtharrest-specific gene 6-mediated survivalpathway by adenosine5'-monophosphate-activated protein kinase.Endocrinology 149(4)
  
  Pages: 1646-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590854
[Journal Article] Association ofplasma dehydroepiandrosterone-sulfate levelswith endothelial function in postmenopausalwomen with coronary risk factors2008
- Author(s)
  Akishita M, Hashimoto M, Ohike Y, Ogawa S,Iijima K, Eto M, Ouchi Y.
- Journal Title
  
  Hypertens Res 31(1)
  
  Pages: 69-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590854
[Journal Article] Sirt1 modulates prematuresenescence-like phenotype in humanendothelial cells2007
- Author(s)
  Ota H, Akishita M, Eto M, Iijima K, KanekiM, Ouchi Y.
- Journal Title
  
  J Mol Cell Cardiol 43(5)
  
  Pages: 571-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590854
[Journal Article] Tako-tsubo-like left ventriculardysfunction in a patient with chronic totalocclusion of the left anterior descending artery2007
- Author(s)
  Kojima T, Ako J, Eto M, Iijima K, AkishitaM, Ouchi Y.
- Journal Title
  
  Int J Cardiol 119(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590854
[Journal Article] Gas6/Axl-PI, 3K/Aktpathway plays a central role in the effect ofstatins on inorganic phosphate-inducedcalcification of vascular smooth muscle cells2007
- Author(s)
  Son BK, Kozaki K, Iijima K, Eto M, Nakano T, Akishita M, Ouchi Y.
- Journal Title
  
  Eur J Pharmacol 556
  
  Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590854
[Journal Article] Sirt1 modulates premature senescence-like phenotype in human endothelial cells.2007
- Author(s)
  Ota H, Akishita M, Eto M, lijima K, Kaneki M, Ouchi Y.
- Journal Title
  
  J Mol Cell Cardiol. 43
  
  Pages: 571-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590801
[Journal Article] Gas6/Ax1-PI3K/Akt pathway plays a central role in the effect of statins on inorganic phosphate-induced calcification of vascular smooth muscle cells.2007
- Author(s)
  Son BK, Kozaki K, Iijima K, Eto M, Nakano T, Akishita M, Ouchi Y
- Journal Title
  
  Eur J Pharmacol. 556
  
  Pages: 1-8
- Data Source
  KAKENHI-PROJECT-18590801
[Journal Article] Low testosteronelevel is an independent determinant ofendothelial dysfunction in men2007
- Author(s)
  Akishita M, Hashimoto M, Ohike Y, OgawaS, Iijima K, Eto M, Ouchi Y.
- Journal Title
  
  Hypertens Res 30(11)
  
  Pages: 1029-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590854
[Journal Article] Gas6/Axl-Pl3K/Akt pathway plays a central role in the effect of statins on inorganic phosphate-induced calcification of vascular smooth musclece cells2007
- Author(s)
  Son BK, Kozaki K, lijima K, EtoM, Nakano T, Akishita M, Ouchi Y.
- Journal Title
  
  Eur J Pharmacol. 556
  
  Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590854
[Journal Article] Sirt1 modulates premature senescence-like phenotype In human endothelial cells2007
- Author(s)
  Ota H, Akishita M, Eto M, hijima K, Kaneki M, Ouchi Y
- Journal Title
  
  J Mol Cell Cardiol 43(5)
  
  Pages: 571-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590801
[Journal Article] Signaling pathway of nitric oxide production induced by ginsenoside rbl in buman aortic endothelial cell : A possible involvement of androgen receptor.2007
- Author(s)
  Yu J, Eto M, Akishita M, Kaneko A, Ouchi Y, Okabe T
- Journal Title
  
  Biochem Biophys Res Commun. 353
  
  Pages: 764-769
- Data Source
  KAKENHI-PROJECT-18590801
[Journal Article] Sirtl modulates premature senescence-like phenotype in human endothelial cells.2007
- Author(s)
  Ota H, Akishita M, Eto M, Iijima K, Kaneki M, Ouchi Y
- Journal Title
  
  J Mol Cell Cardio1 43(5)
  
  Pages: 571-9
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590801
[Journal Article] Statins protect human aortic smooth muscle cells from inorganic phosphate-induced calcification by restoring Gas6-axl survival pathway.2006
- Author(s)
  Son BK, Iijima K, Eto M, Kojirna T, Ouchi Y, et al.
- Journal Title
  
  Circulation Res (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Sirtl inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells.2006
- Author(s)
  Ota H, Iijima K, Eto M, Ouchi Y, et al.
- Journal Title
  
  Oncogene 25(2)
  
  Pages: 176-85
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Statins Protect Human Aortic Smooth Muscle Cells from Inorganic Phosphate-induced Calcification by Restoring Gas6-Axl Survival Pathway.2006
- Author(s)
  Son BK、Kozai K, Iijima K, Eto M, Kojima T, Ota H, Senda Y, Maemura K, Nakano T, Akishita M, Ouchi Y.
- Journal Title
  
  Circulation Res (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Statins protect human aortic smooth muscle cells from inorganic phosphate-induced calcification by restoring Gas6-Ax1 survival pathway.2006
- Author(s)
  Son BK, Kozaki K, Iijima K, Eto M, Kojima T, Ota H, Senda Y, Maemura K, Nakano T, Akishita M, Ouchi Y
- Journal Title
  
  Circ Res 98
  
  Pages: 1024-1031
- Data Source
  KAKENHI-PROJECT-18590801
[Journal Article] Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells. Oncogene.2006
- Author(s)
  Ota H, Tokunaga E, Chang K, Hikasa M, Iijima K, Eto M, Kozai K, Akishita M, Ouchi Y, Kaneki M.
- Journal Title
  
  Oncogene. 25(2)
  
  Pages: 176-185
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells.2006
- Author(s)
  Ota H, Iijima K, Eto M, Ouchi Y, et al.
- Journal Title
  
  Oncogene 25(2)
  
  Pages: 176-185
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Statins Protect Human Aortic Smooth Muscle Cells from Inorganic Phosphate-induced Calcification by Restoring Gas6-Axl Survival Pathway.2006
- Author(s)
  Son BK, Iijima K, Eto M, Kojima T, Ouchi Y, et al.
- Journal Title
  
  Circulation Res (in press)
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric NG. NG-dimethvlarginine2005
- Author(s)
  Ohike Y, Kozaki K, Ouchi Y, et al.
- Journal Title
  
  Circ J 69(2)
  
  Pages: 211-6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] VEGF-A and FGF-2 synergistically promote neoangiogenesis through enhancement of endogenous PDGF-B/PDGFR β signalling.2005
- Author(s)
  Kano MR, Morishita Y, Iwata C, Iwasaka S, Watanabe T, Ouchi Y, Miyazono K, Miyazawa K.
- Journal Title
  
  J Cell Sci. 118(Pt16)
  
  Pages: 3759-3768
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Impact of blood pressure variability on cardiovascular events in elderly patients with hypertension.2005
- Author(s)
  Eto M, Toba K, Akishita M, Kozaki K, Watanabe T, Kim S, Hashimoto M, Ako J, Iijima K, Sudoh N, Yoshizumi M, Ouchi Y.
- Journal Title
  
  Hypertens Res. 28(1)
  
  Pages: 1-7
- NAID
  10016430046
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric NG, NG-dimethylarginine.2005
- Author(s)
  Ohike Y, Kozaki K, Ouchi Y, et al.
- Journal Title
  
  Circ J. 69(2)
  
  Pages: 221-226
- NAID
  110002696075
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] VEGF-A and FGF-2 synergistically promote neoangiogenesis through enhancement of endogenous PDGF-B/PDGFR βsignaling.2005
- Author(s)
  Kano MR, Ouchi Y, Miyazono K, et al.
- Journal Title
  
  J Cell Sci 118(Pt 16)
  
  Pages: 3759-68
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] VEGF-A and FGF-2 synergistically promote neoangiogenesis through enhancement of endogenous PDGF-B/PDGFRβ signaling.2005
- Author(s)
  Kano MR, Ouchi Y, Miyazono K, et al.
- Journal Title
  
  J Cell Sci 118(Pt16)
  
  Pages: 3759-3768
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] HMG Co-A reductase inhibitors (stains) inhibit vascular muscle cell (VSMC) calcification through upregulation of Gas6-Axl survaival pathway2005
- Author(s)
  Son BK, Kozaki K, Ouchi Y, et al.
- Journal Title
  
  Circ J 69(Suppl 1)
  
  Pages: 555-555
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] HMG Co-A reductase inhibitors (stains) inhibit vascular muscle cell(VSMC) calcification through upregulation of Gas6-Axl survaival pathway2005
- Author(s)
  Son BK, Kozaki K, Ouchi Y, et al.
- Journal Title
  
  Circ J 69(Suppl 1)
  
  Pages: 555-555
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Impact of blood pressure variability on cardiovascular events in elderly patients with hypertension.2005
- Author(s)
  Eto M, Ouchi Y, et al.
- Journal Title
  
  Hypertens Res 28(1)
  
  Pages: 1-7
- NAID
  10016430046
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric NG, NG-dimethylarginine2005
- Author(s)
  Ohike Y, Kozaki K, Ouchi Y, et al.
- Journal Title
  
  Circ J 69(2)
  
  Pages: 221-226
- NAID
  110002696075
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric NG, NG-dimethylarginine.2005
- Author(s)
  Ohike Y, Kozaki K, Iijima K, Eto M, Kojima T, Ohga E, Santa T, Imai K, Hashimoto M, Yoshizumi M, Ouchi Y.
- Journal Title
  
  Circ J. 69(2)
  
  Pages: 221-226
- NAID
  110002696075
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Caveolin-1, ld3a and two LIM protein genes are upregulated by estrogen in vascular smooth muscle cells.2004
- Author(s)
  Watanabe T, Akishita M, Ouchi Y, et al.
- Journal Title
  
  Life Sci. 75(10)
  
  Pages: 1219-1229
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Caveolin-1, Id3a and two LIM protein genes are upregulated by estrogen in vascular smooth muscle cells.2004
- Author(s)
  Watanabe T, Akishita M, Ouchi Y, et al.
- Journal Title
  
  Life Sci. 75(10)
  
  Pages: 1219-1229
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Inhibitory effect of low-dose estrogen on neointimal formation after balloon injury of rat carotid artery.2004
- Author(s)
  Watanabe T, Miyahara Y, Ouchi Y, et al.
- Journal Title
  
  Eur J Pharmacol. 502(3)
  
  Pages: 265-270
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] 17 beta-estradiol inhibits cardiac fibroblast growth through both subtypes of estrogen receptor.2003
- Author(s)
  Watanabe T, Ouchi Y, et al.
- Journal Title
  
  Biochem Biophys Res Commun 311(2)
  
  Pages: 454-459
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Reduced endothelial vasomotor function and enhanced neointimal formation after vascular injury in a rat model of blood pressure lability.2003
- Author(s)
  Eto M, Ouchi Y, et al.
- Journal Title
  
  Hypertens Res. 26(12)
  
  Pages: 991-998
- NAID
  50000378359
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] HMG Co-A reductase inhibitors inhibit human vascular smooth muscle cell calcification ---Another pleiotropic effect of statins.2003
- Author(s)
  Son B, Ouchi Y, et al.
- Journal Title
  
  Atherosclerosis Supplements Vol.4
  
  Pages: 213-213
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Inhibitory effect of HMG Co-A reductase inhibitors on vascular smooth muscle cell calcification in vitro.2003
- Author(s)
  Son B, Ouchi Y, et al.
- Journal Title
  
  Circ J 67(suppl.1)
  
  Pages: 407-407
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Estrogen receptor beta mediates the inhibitory effect of estradiol on vascular smooth muscle cell proliferation.2003
- Author(s)
  Watanabe T, Ouchi Y, et al.
- Journal Title
  
  Cardiovasc Res. 59(3)
  
  Pages: 734-744
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Sirolimus andEverolimus induce endothelial cellularsenescence via sirt1 downregulation : Therapeutic implication of Cilostazol afterdrug-eluting stent implantation
- Author(s)
  Ota H, Eto M, Ako J, Ogawa S, Iijima K,Akishita M, Ouchi Y.
- Journal Title
  
  J Am Coll Cardiol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] Plasma Sex Hormone Levels and Mortality in Disabled Older Men2010
- Author(s)
  Fukai S, Ouchi Y, et al
- Organizer
  Men's Health World Congress
- Place of Presentation
  Nice, France
- Data Source
  KAKENHI-PROJECT-20249041
[Presentation] 長寿遺伝子Sirt1と血管の老化2010
- Author(s)
  大内尉義
- Organizer
  日本抗加齢医学会総会
- Place of Presentation
  京都
- Year and Date
  2010-06-13
- Data Source
  KAKENHI-PROJECT-20249041
[Presentation] Association of low testosterone level with the metabolic syndrome and its components in middle-aged Japanese men2010
- Author(s)
  Umeda-Kameyama Y, Ouchi Y, et al
- Organizer
  Men's Health World Congress
- Place of Presentation
  Nice, France
- Data Source
  KAKENHI-PROJECT-20249041
[Presentation] 地域在住高齢者における食品摂取状況の性差およびるい痩との関連性2010
- Author(s)
  柴崎孝二、大内尉義, ほか
- Organizer
  日本成人病(生活習慣病)学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20249041
[Presentation] 老年病科入院患者における老年症候群重積数からみた性差2010
- Author(s)
  亀山祐美、大内尉義, ほか
- Organizer
  日本性差医学・医療学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20249041
[Presentation] Src kinase mediates non-genomic pathway of endothelial nitric oxide synthase activation by testosterone in vascular endothelial cell2010
- Author(s)
  Yu J, Ouchi Y, et al
- Organizer
  日本動脈硬化学会学術集会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-20249041
[Presentation] 医学部生への性差医学・医療教育への取り組み-老年病科BSL中に実施している性差医学医療セミナーに関して-2010
- Author(s)
  宮尾益理子、大内尉義, ほか
- Organizer
  日本性差医学・医療学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20249041
[Presentation] Vascular endothelial cell senescence and Sir2/Sirt12010
- Author(s)
  大内尉義
- Organizer
  The World Economic Forum Annual Meeting 2010
- Place of Presentation
  Tianjin, China
- Data Source
  KAKENHI-PROJECT-20249041
[Presentation] 中高年男性の健康とアンドロゲン2010
- Author(s)
  大内尉義
- Organizer
  日本内科学会中国支部生涯教育講演会
- Place of Presentation
  岡山
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-20249041
[Presentation] 長寿遺伝子Sirtlと血管の老化2010
- Author(s)
  大内尉義
- Organizer
  第10回日本抗加齢医学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20249041
[Presentation] 【老年医学教育わが国における問題点と展望】基調講演:老年医学教育の過去・現在・未来.2009
- Author(s)
  大内尉義
- Organizer
  第51回日本老年医学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20249041
[Presentation] 高齢生活習慣病患者における易転倒性の加齢変化と性差2009
- Author(s)
  小島太郎、大内尉義, ほか
- Organizer
  日本老年医学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20249041
[Presentation] 血清テストステロン低値は血管内皮機能とは独立して中高年男性患者の心血管イベントに関連す2008
- Author(s)
  秋下雅弘, 橋本正良, 小島太郎, 飯島勝矢,江頭正人, 大内尉義
- Organizer
  第31回日本高血圧学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] Vascular calcification as therapeutic in CKD patients2008
- Author(s)
  秋下雅弘、飯島勝矢、大内尉義
- Organizer
  第72回日本循環器学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] Metabolic risk factor clustering and visceral fat accumulation in the elderly.2008
- Author(s)
  Ouchi Y.
- Organizer
  US-Japan Symposium on Nutrition and Metabolism.
- Place of Presentation
  Ho Chi Minn and Hanoi, Vi etnam.
- Data Source
  KAKENHI-PROJECT-20249041
[Presentation] Nitric oxide blocksoxidative stress induced premature endothelialsenescence by the longevity gene, Sirt 12008
- Author(s)
  大田秀隆、江頭正人、小川純人、飯島勝矢、秋下雅弘、大内尉義
- Organizer
  第72回日本循環器学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] ヒト血管内皮細胞におけるNO産生増加による細胞老化抑制機構2008
- Author(s)
  大田秀隆, 江頭正人, 小川純人, 飯島勝矢,秋下雅弘, 大内尉義
- Organizer
  第50回日本老年医学会学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] ヒト血管内皮細胞におけるNO産生増加薬剤による細胞老化抑制機構2008
- Author(s)
  大田秀隆, 江頭正人, 小川純人, 飯島勝矢, 秋下雅弘, 大内尉義
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] 脂肪細胞に異所性に発現するeNOSは脂肪分解に対し抑制的にはたらく2008
- Author(s)
  山田容子, 江頭正人, 伊藤友紀, 野村和至,大田秀隆, 孫輔卿, 小川純人, 飯島勝矢, 秋下雅弘, 大内尉義
- Organizer
  第40回日本動脈硬化学会学術集会
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] 胸部単純X 線における大動脈弓石灰化はどこまで心血管イベント発症に対する強い予測因子になりうるのか?2008
- Author(s)
  飯島勝矢, 橋本寛子, 橋本正良, 小川純人, 江頭正人, 秋下雅弘, 大内尉義
- Organizer
  第31回日本高血圧学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] 高齢者糖尿病患者におけるメタボリック・シンドロームは摂取カロリーよりもPhysical activity(生活活動強度)の低下が大きく関与す2008
- Author(s)
  飯島勝矢, 飯室聡, 大橋靖雄, 櫻井孝, 荒木厚, 大内尉義, 井藤英喜
- Organizer
  第50回日本老年医学会学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] 大動脈弓石灰化の評価による心血管イベントの予測慢性腎臓病CKDとの関連.2008
- Author(s)
  飯島勝矢,橋本寛子,江頭正人,大田秀隆,野村和志,山田容子,秋下雅弘,大内尉義.
- Organizer
  第50回日本老年医学会学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] 高齢女性における内臓脂肪増加および全身筋肉量低下とメタボリックシンドローム構成因子の重複に関する横断研究2008
- Author(s)
  野村和至, 江頭正人, 中村哲郎, 小島太郎,小川純人, 飯島勝矢, 荒木厚, 秋下雅弘, 大内尉義
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] 大動脈弓石灰化の評価による心血管イベントの予測慢性腎臓病CKDとの関連2008
- Author(s)
  飯島勝矢, 橋本寛子, 江頭正人, 大田秀隆, 野村和志, 山田容子, 秋下雅弘, 大内尉義
- Organizer
  第50回日本老年医学会学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] Cilostazol, a Selective Inhibitor of PDE3, Blocked Oxidative Stress-induced Premature Senescence of Human Endothelial Cells.2007
- Author(s)
  大田秀隆, 江頭正人, 向田修, 飯島勝矢, 秋下雅弘, 大内尉義
- Organizer
  第71回日本循環器学会総会・学術集会
- Place of Presentation
  神戸
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590801
[Presentation] Cilostazol, A selective inhibitor of PDE3, Increases Resistance Against Oxidative Stress-induced premature senescence in human endothelial cells2007
- Author(s)
  Ota H, Eto M, Ogawa S, Iijima K, Akishita M, Ouchi Y
- Organizer
  The 8th Asia/Oceania Regional Congress of Gerontology and Geriatrics
- Place of Presentation
  Beijing
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590801
[Presentation] The associationof polypharmacy and hypertension with fallrisks among the elderly patients2007
- Author(s)
  Kojima T, Akishita M, Yamaguchi K, OhikeY, Iijima K, Eto M, Ouchi Y.
- Organizer
  The 8thAsia/Oceania Regional Congress ofGerontology and Geriatrics
- Place of Presentation
  Beijing
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] PDE3阻害薬、シロスタゾールによるヒト血管内皮細胞のPremature senescence抑制機構2007
- Author(s)
  大田秀隆, 江頭正人, 小川純人, 飯島勝矢, 秋下雅弘, 大内尉義
- Organizer
  第49回日本老年医学会学術集会
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590801
[Presentation] 血管平滑筋細胞の石灰化に対するTNFαの促進作用及びadiponectinの拮抗作用2007
- Author(s)
  孫輔卿, 飯島勝矢, 江頭正人, 秋下雅弘,大内尉義
- Organizer
  第39回日本動脈硬化学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] 高齢者の動脈硬化危険因子の重複に内臓脂肪が及ぼす影響に関する臨床研究2007
- Author(s)
  野村和至, 秋下雅弘, 中村哲郎, 山田優子, 小島太郎, 大池裕美子, 飯島勝矢, 荒木厚, 江頭正人, 大内尉義
- Organizer
  第104回日本内科学会総会・講演会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] 高齢者の腹部大動脈石灰化と腎機能障害との関連についての検討2007
- Author(s)
  野村和至, 秋下雅弘, 中村哲郎, 小島太郎, 大池裕美子, 飯島勝矢, 江頭正人, 大内尉義
- Organizer
  第39回日本動脈硬化学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] PDE3阻害薬, シロスタゾールによる血管内皮prematuresenescence抑制作用メカニズム2007
- Author(s)
  大田秀隆, 江頭正人, 小川純人, 飯島勝矢, 秋下雅弘, 大内尉義
- Organizer
  第39回日本動脈硬化学会総会学術集会
- Place of Presentation
  大阪
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590801
[Presentation] SIRT1阻害によるヒト血管平滑筋細胞増殖抑制と細胞老化形質誘導2007
- Author(s)
  小林貴、大田秀隆、小川純人、飯島勝矢、江頭正人、秋下雅弘、金木正夫、大内尉義
- Organizer
  第39回日本動脈硬化学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] Cilostazol, a Selective Inhibitor of PDE3, Inhibited Oxidative Stress-induced Premature Senescence of Human Endothelial Cells2007
- Author(s)
  Ota H, Eto M, Ogawa S, Iijima K, Akishita M Ouchi Y
- Organizer
  The 49th Annual Meeting of the Japan Geriatrics Society
- Place of Presentation
  Sapporo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590801
[Presentation] 血管細胞老化と動脈硬化PDE3阻害薬、シロスタゾールによる血管内皮premature senescence 抑制作用メカニズム2007
- Author(s)
  大田秀隆, 江頭正人, 飯島勝矢, 秋下雅弘, 大内尉義
- Organizer
  第39回日本動脈硬化学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] PDE3阻害薬、シロスタゾールによる血管内皮細胞老化抑制作用2007
- Author(s)
  大田秀隆, 江頭正人, 小川純人, 飯島勝矢, 秋下雅弘, 大内尉義
- Organizer
  東京大学生命科学研究ネットワークシンポジウム
- Place of Presentation
  東京
- Year and Date
  2007-09-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590801
[Presentation] Angiotensin-II receptorblocker enhances the inhibitory effect ofstatins on vascular calcification in uremic ratsinduced by adenine diet2007
- Author(s)
  飯島勝矢、伊藤友紀、孫輔卿、江頭正人、小川純人、大池由美子、小島太郎、大田秀隆、野村和至、橋本寛子、山田容子、秋下雅弘、大内尉義
- Organizer
  第71回日本循環器学会総会・学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] 慢性腎臓病CKDにおける心血管石灰化2007
- Author(s)
  飯島勝矢, 孫輔卿, 伊藤友紀, 江頭正人, 大池裕美子, 小島太郎, 大田秀隆, 野村和至, 秋下雅弘, 大内尉義
- Organizer
  第39回日本動脈硬化学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-07-13
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] PDE3阻害薬、シロスタゾールによる血管内皮premature senescence抑制作用メカニズム2007
- Author(s)
  大田秀隆, 江頭正人, 飯島勝矢, 秋下雅弘, 大内尉義
- Organizer
  第39回日本動脈硬化学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-07-13
- Data Source
  KAKENHI-PROJECT-18590801
[Presentation] Cilostazol, a selectiveinhibitor of PDE3, blocked oxidativestress-induced premature senescence ofhuman endothelial cells2007
- Author(s)
  大田秀隆、江頭正人、向田修、飯島勝矢、秋下雅弘、大内尉義
- Organizer
  第71回日本循環器学会総会・学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] Blockade of Angiotensin II receptorenhances the inhibitory effect of statin onvascular calcification in renal failure rats2007
- Author(s)
  Iijima K, Ito Y, Son BK, Eto M, Ogawa S Ota H, Nomura K, Yamada Y, Akishita M, Ouchi Y.
- Organizer
  Scientific Sessions of American HeartAssociation, Orlando
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] Obstructivesleep apnea exacerbates endothelialdysfunction in patients with metabolicsyndrome2007
- Author(s)
  Akishita M, Ohike Y, Hashimoto M, Iijima K,Eto M, Teramoto S, Ouchi Y.
- Organizer
  Scientific Sessions of AmericanHeart Association, Orlando
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] Cilostazol, A selective inhibitor ofPDE3, Increases Resistance Against OxidativeStress-induced premature senescence inhuman endothelial cells2007
- Author(s)
  Ota H, Eto M, Ogawa S, Iijima K, AkishitaM Ouchi Y.
- Organizer
  The 8th Asia/OceaniaRegional Congress of Gerontology andGeriatrics
- Place of Presentation
  Beijing
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] Cilostazol, a Selective Inhibitor of PDE3, Blocked Oxidative, Stress-induced Premature Senescence of Human Endothelial Cells2007
- Author(s)
  Ota H, Eto M, Mukoda O, Iijima K, Akishita M, Ouchi Y
- Organizer
  The 71st Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  Kobe
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590801
[Presentation] PDE3阻害薬、シロスタゾールによるヒト血管内皮細胞のpremature senescence抑制機構2007
- Author(s)
  大田秀隆、江頭正人、向田修、小川純人、飯島勝矢、秋下雅弘、大内尉義
- Organizer
  第49回日本老年医学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] Inhibitory Effects of Cilostazol, a Selective Inhibitor of PDE3, On Oxidative Stress-induced Premature Senescence of Human Endothelial Cells2007
- Author(s)
  Ota H, Eto M, Ogawa S, Iijima K, Akishita M Ouchi Y
- Organizer
  The 39th Annual Scientific Meeting of the Japan Atherosclerosis Society
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590801
[Presentation] Adiponectinantagonizes the stimulatory effect of TNF alfaon vascular smooth muscle cell calcification2007
- Author(s)
  孫輔卿、飯島勝矢、神崎恒一、江頭正人、前村浩二、秋下雅弘、大内尉義
- Organizer
  第71回日本循環器学会総会・学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590854

1. AKISHITA Masahiro (00261975)

# of Collaborated Projects: 12 results

# of Collaborated Products: 79 results
2. ETO Masato (80282630)

# of Collaborated Projects: 8 results

# of Collaborated Products: 86 results
3. KOZAKI Koichi (80272540)

# of Collaborated Projects: 8 results

# of Collaborated Products: 7 results
4. IIJIMA Katsuya (00334384)

# of Collaborated Projects: 7 results

# of Collaborated Products: 78 results
5. INOUE Satoshi (40251251)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
6. OHIKE Yumiko (20359615)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
7. 折茂肇 (00143438)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. NAGANO Koichiro (30282627)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. TOBA Kenji (60155546)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. OGAWA Sumito (20323579)

# of Collaborated Projects: 2 results

# of Collaborated Products: 35 results
11. OTA Hidetaka (20431869)

# of Collaborated Projects: 2 results

# of Collaborated Products: 28 results
12. YOSHIZUMI Masao (20282626)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. MURASHIMA Sachiyo (60123204)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 服部明徳 (20198758)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 中村哲郎 (30172414)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. 阿古潤哉 (60292744)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. WATANABE Tokurnitsu

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. SANTA Tomohumi (30187306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. NAGATA Satoko (80323616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TAKAHASHI Ryutaro (20150881)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. HARUNA Megumi (00332601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KOJIMA Taro (40401111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
23. 難波吉雄 (80228113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 細井孝之 (40240709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 池田和彦 (30124663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 合原一幸 (40167218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 市丸雄平 (70038909)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 三村昌康 (50068128)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 熊田衛 (00110487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 金承範 (30254907)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 盛田俊介

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 水野有三

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 金木正夫

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 甘利俊一

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OUCHI Yasuyoshi 大内 尉義

大内 尉義 オオウチ ヤスヨシ

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Investigation for the establishment of gender-sensitive geriatric medicinePrincipal Investigator

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Molecular mechanisms and novel therapeutic approaches for cardiovascular calcificationPrincipal Investigator

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Investigation and clinical application to the prevention of estrogen receptor α and β prevent vascular disease.Principal Investigator

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Investigation and clinical application of estrogen receptor α and β prevent vascular diseasePrincipal Investigator

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神経細胞死とアポリポ蛋白受容体についてPrincipal Investigator

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循環系のホメオスタシスとその異常の基本原理に関する新しい統合的アプローチPrincipal Investigator

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血管内皮細胞機能に及ぼす血圧日内変動の影響Principal Investigator

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OUCHI Yasuyoshi 大内尉義

大内尉義オオウチヤスヨシ

[Book] 新老年学第3版2010

[Book] 新老年学第3版2010