Tanaka Kohichi 田中光一

… Alternative Names

TAKANO Kohichi 田中光一

田中光一タナカコウイチ

Less

Researcher Number	80171750
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2014 – 2023: 東京医科歯科大学, 難治疾患研究所, 教授 2007 – 2011: Tokyo Medical and Dental University, 大学院・疾患生命科学研究部, 教授 2009: Tokyo Medical and Dental University, 疾患生命科学研究部, 教授 2006: 東京医科歯科大学, 大学院疾患生命科学研究部, 教授 2003 – 2005: 東京医科歯科大学, 大学院・疾患生命科学研究部, 教授 … More 1998 – 2002: 東京医科歯科大学, 難治疾患研究所, 教授 2000: 東京医科歯科大学, 難治症患研究所, 教授 1997: 国立精神・神経センター, 神経研究所・疾病四部, 室長 1995: 国立精神, 神経センター・神経研究所・疾病研究第4部, 室長 1995: 国立精神・神経センター, 神経研究所・疾病研究第四部, 室長 1993 – 1994: 国立精神・神経センター, 神経研究所・疾病4部, 室長 1993: 国立精神・神経センター, 神経研究所疾病4部, 室長 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Neurochemistry/Neuropharmacology / Medium-sized Section 51:Brain sciences and related fields / Neurochemistry/Neuropharmacology / Basic / Social brain science / Biological Sciences / Neurochemistry/Neuropharmacology Except Principal Investigator Neurochemistry/Neuropharmacology / Cerebral neurosurgery
Keywords	Principal Investigator グルタミン酸 / トランスポーター / 神経科学 / 欠損マウス / 発生・分化 / 脳神経 / シナプス伝達 / アストロサイト / 神経伝達物質 / 小脳 … More / 興奮毒性 / ゲノム編集 / 抑制性ニューロン / 発達 / アポトーシス / グリア細胞 / 星状細胞 / 籠細胞 / ノッチ / グリア / 網膜 / 脳・神経 / 細胞移動 / 中枢神経系 / 発生 / 可塑性 / 神経細胞死 / 神経変性疾患 / 神経細胞 / 分化転換 / CRISPR/Cas / ゲノム記録 / DNA / 記録 / 神経活動 / 間接路 / 直接路 / 線条体 / 体温調節 / glial cells / knockout mice / glutamate / development and differentiation / brain and neuron / neuroscience / knockout mouse / epilepsy / Plasticity / excitotoxicity / synaptic transmission / transporter / Glutamate / てんかん発作 / てんかん / 脳神経疾患 / プルキン細胞 / シナプス / 登状線維 / プルキンエ細胞 / 神経前駆細胞 / 遺伝子欠損マウス / 抑制性神経細胞 / 酸化ストレス / 緑内障 / 移動 / 神経幹細胞 / 脳 / グルタミン酸受容体 / Clチャンネル / C1チャネル / GABA / ノックアウトマウス / トサンスポーター / 放出過程 … More Except Principal Investigator GLT-1 / ischemia / 脳虚血 / 海馬CA1野 / KO mouse / microdialysis / hippocampus / glia / transporter / glutamate neurotoxicity / GLT-1ノックアウトマウス / グルタミン酸毒性 / ノックアウトマウス / マイクロダイアリシス / グリア細胞 / グルタミン酸トランスポーター / グルタミン酸神経毒性 / hippocambal CA1 / gene / neuronal death / hypothermia / ニューロン死防御 / 海馬CA1 / 保護機構 / 低温 / 遺伝子 / ニューロン死 / 虚血 / 脳低温 / プロモーター / in situ hybridization / mRNA / 遺伝子クローニング / トランスポーター / グルタミン酸 Less

Functional reconstruction of neural circuits using differentiation of astrocytes into neuronsPrincipal Investigator
- Principal Investigator
  
  Tanaka Kohichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 51:Brain sciences and related fields
- Research Institution
  Tokyo Medical and Dental University
Recording neuronal activities onto DNAPrincipal Investigator
- Principal Investigator
  
  Tanaka Kohichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 51:Brain sciences and related fields
- Research Institution
  Tokyo Medical and Dental University
Circuit-specific neuron-astrocyte cross-talk in the striatumPrincipal Investigator
- Principal Investigator
  
  Tanaka Kohichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Basic / Social brain science
- Research Institution
  Tokyo Medical and Dental University
アストロサイトによる体温調節機序の解明Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Molecular mechanisms of astrocyte heterogeneityPrincipal Investigator
- Principal Investigator
  
  Tanaka Kohichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo Medical and Dental University
Molecular mechanisms of subcellular synapse organization in cerebellar Purkinje neuronsPrincipal Investigator
- Principal Investigator
  
  TANAKA Kohichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo Medical and Dental University
抑制性神経前駆細胞の実体解明と神経分化におけるノッチシグナルの役割Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
グリア伝達物質の機能解析Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
グルタミン酸トランスポーターの発現細胞による機能的差異Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
The differentiation and function of molecular-layer interneurons in the cerebellumPrincipal Investigator
- Principal Investigator
  
  TAKANO Kohichi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo Medical and Dental University
グリア伝達物質の機能解析Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
脳の発達におけるグルタミン酸トランスポーターの役割Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
脳の発達におけるグルタミン酸トランスポーターの役割Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
グリア細胞に存在するNMDA受容体の機能解析Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
興奮性神経伝達物質としてのGABAの機能的役割Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
脳の発達におけるグルタミン酸トランスポーターの役割Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Role of glial cells in brain developmentPrincipal Investigator
- Principal Investigator
  
  TANAKA Kohichi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo Medical and Dental University
脳の発達におけるグルタミン酸トランスポーターの役割Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
中枢神経系系形成シグナル分子としてのグルタミン酸の役割Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
脳の発達におけるグルタミン酸トランスポーターの役割Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
The effect of hypothermia on gene expression in the ischemic hippocampal CAI
- Principal Investigator
  
  MITANI Akira
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  KYOTO UNIVERSITY
Functional Change of Glutamate Transporter GLT-1 during Ischemia
- Principal Investigator
  
  MITANI Akira
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  KYOTO UNIVERSITY
  Ehime University
グルタミン酸トランスポーター欠損マウスを用いた可塑性遺伝子の検索Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tokyo Medical and Dental University
Analysis of the mechanisms of epilepsy induced by dysfunction of glutamate transportersPrincipal Investigator
- Principal Investigator
  
  TANAKA Kohichi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo Medical and Dental University
グルタミン酸トランスポーター欠損マウスを用いたグルタミン酸細胞死機序の解析Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Center of Neurology and Psychiatry
グルタミン酸トランスポーターの生理学的・病態生理学的役割の解明Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Center of Neurology and Psychiatry
ニューロンの興奮性・抑制性の選択を決定する分子機構の解明
- Principal Investigator
  
  和田圭司
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Center of Neurology and Psychiatry
シナプスにおけるグルタミン酸の動態に関与する機能分子の単離Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Center of Neurology and Psychiatry
グルタミン酸トランスポーターのグルタミン酸輸送機構の解明Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Center of Neurology and Psychiatry
グルタミン酸放出過程に関与する新機能分子の体系的検索Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Center of Neurology and Psychiatry
グルタミン酸トランスポーターのクローニングとその特性解析Principal Investigator
- Principal Investigator
  
  田中光一
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Center of Neurology and Psychiatry

[Book] 精神神経疾患におけるグルタミン酸トランスポーターの役割、細胞工学2012
- Author(s)
  田中光一
- Data Source
  KAKENHI-PROJECT-21300137
[Book] アストロサイトと精神神経疾患、Clinical Neuroscience2011
- Author(s)
  田中光一
- Data Source
  KAKENHI-PROJECT-21300137
[Book] 自閉症、Clinical Neuroscience2010
- Author(s)
  相田知海、田中光一
- Data Source
  KAKENHI-PROJECT-21300137
[Book] グルタミン酸トランスポーター、生体の科学2010
- Author(s)
  相田知海、田中光一
- Data Source
  KAKENHI-PROJECT-21300137
[Journal Article] Functional synergy of a human-specific and an ape-specific metabolic regulator in human neocortex development2024
- Author(s)
  Xing Lei、Gkini Vasiliki、Nieminen Anni I.、Zhou Hui-Chao、Aquilino Matilde、Naumann Ronald、Reppe Katrin、Tanaka Kohichi、Carmeliet Peter、Heikinheimo Oskari、P??bo Svante、Huttner Wieland B.、Namba Takashi
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1
- DOI
  10.1038/s41467-024-47437-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19425
[Journal Article] Astrotactin 2 ( <scp>ASTN2</scp> ) regulates emotional and cognitive functions by affecting neuronal morphogenesis and monoaminergic systems2023
- Author(s)
  Ito Takahiro、Yoshida Mikio、Aida Tomomi、Kushima Itaru、Hiramatsu Yuka、Ono Maiko、Yoshimi Akira、Tanaka Kohichi、Ozaki Norio、Noda Yukihiro
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: in press Issue: 2 Pages: 211-229
- DOI
  10.1111/jnc.15790
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06719, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-22K06755, KAKENHI-PROJECT-21K19425
[Journal Article] Glial modulation of the parallel memory formation2023
- Author(s)
  Kanaya Teppei、Ito Ryo、Morizawa Yosuke M.、Sasaki Daichi、Yamao Hiroki、Ishikane Hiroshi、Hiraoka Yuichi、Tanaka Kohichi、Matsui Ko
- Journal Title
  
  Glia
  
  Volume: 71 Issue: 10 Pages: 2401-2417
- DOI
  10.1002/glia.24431
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KJ0152, KAKENHI-PROJECT-21K19425, KAKENHI-PROJECT-22KJ0262, KAKENHI-PLANNED-20H05896, KAKENHI-PUBLICLY-23H04659, KAKENHI-PROJECT-23K23976
[Journal Article] Synaptic pruning through glial synapse engulfment upon motor learning2022
- Author(s)
  Morizawa Yosuke M.、Matsumoto Mami、Nakashima Yuka、Endo Narumi、Aida Tomomi、Ishikane Hiroshi、Beppu Kaoru、Moritoh Satoru、Inada Hitoshi、Osumi Noriko、Shigetomi Eiji、Koizumi Schuichi、Yang Guang、Hirai Hirokazu、Tanaka Kohichi、Tanaka Kenji F.、Ohno Nobuhiko、Fukazawa Yugo、Matsui Ko
- Journal Title
  
  Nature Neuroscience
  
  Volume: 25 Issue: 11 Pages: 1458-1469
- DOI
  10.1038/s41593-022-01184-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19425, KAKENHI-PROJECT-22K15202, KAKENHI-PLANNED-20H05896, KAKENHI-PLANNED-20H05902, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-21H04786, KAKENHI-PROJECT-22KJ0153, KAKENHI-PROJECT-21K19309, KAKENHI-PROJECT-23K23976
[Journal Article] Exacerbation of Epilepsy by Astrocyte Alkalization and Gap Junction Uncoupling2021
- Author(s)
  Mariko Onodera, Jan Meyer, Kota Furukawa, Yuichi Hiraoka, Tomomi Aida, Kohichi Tanaka, Kenji F. Tanaka, Christine R. Rose and Ko Matsui
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 41 Issue: 10 Pages: 2106-2118
- DOI
  10.1523/jneurosci.2365-20.2020
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05046, KAKENHI-ORGANIZER-20H05894, KAKENHI-PLANNED-20H05896, KAKENHI-PROJECT-19H03338, KAKENHI-PROJECT-19J12139, KAKENHI-PROJECT-18K19494
[Journal Article] Dorsal telencephalon-specific Nprl2- and Nprl3-knockout mice: novel mouse models for GATORopathy2021
- Author(s)
  Ishida Saeko、Zhao Di、Sawada Yuta、Hiraoka Yuichi、Mashimo Tomoji、Tanaka Kohichi
- Journal Title
  
  Human Molecular Genetics
  
  Volume: - Issue: 9 Pages: 1519-1530
- DOI
  10.1093/hmg/ddab337
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05987, KAKENHI-PROJECT-21K19425
[Journal Article] Glial glutamate transporter GLT ‐1 determines susceptibility to spreading depression in the mouse cerebral cortex2020
- Author(s)
  Aizawa Hidenori、Sun Weinan、Sugiyama Kaori、Itou Yukiko、Aida Tomomi、Cui Wanpeng、Toyoda Saori、Terai Haruhi、Yanagisawa Michiko、Tanaka Kohichi
- Journal Title
  
  Glia
  
  Volume: 68 Issue: 12 Pages: 2631-2642
- DOI
  10.1002/glia.23874
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19H05723, KAKENHI-PROJECT-18K19494
[Journal Article] Establishment of a tTA-dependent photoactiveatable Cre recombinease knock-in mouse model for optogenetic genome engineering.2020
- Author(s)
  9.Takao, T., Hiraoka, Y., Kawabe, K., Yamada, D., Ming, L., Tanaka, K., Sato, M., Takarada, T.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 526 Issue: 1 Pages: 213-217
- DOI
  10.1016/j.bbrc.2020.03.015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19494, KAKENHI-PROJECT-19K18705, KAKENHI-PROJECT-17H02216, KAKENHI-PROJECT-17H04399
[Journal Article] Dopaminergic signaling in the nucleus accumbens modulates stress-coping strategies during inescapable stress.2020
- Author(s)
  Cui, W., Aida, T., Ito, H., Kobayashi, K., Wada, Y., Kato, S., Nakano, T., Zhu, M., Isa, K., Kobayashi, K., Isa, T., Tanaka, K. and Aizawa, H.
- Journal Title
  
  J Neurosci.
  
  Volume: 40 Issue: 38 Pages: 7241-7254
- DOI
  10.1523/jneurosci.0444-20.2020
- NAID
  120007170786
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06912, KAKENHI-PLANNED-19H05723, KAKENHI-PROJECT-18K06504, KAKENHI-PROJECT-18K19494
[Journal Article] Functional roles of glial glutamate transporter (GLAST) in emotional and cognitive abnormalities of mice after repeated phencyclidine administration.2019
- Author(s)
  chida, M., Hida, H., Mori, K., Yoshimi, A., Kitagaki, S., Yamada, K., Hiraoka, Y., Aida, T., Tanaka, K., Ozaki, N., Noda, Y.
- Journal Title
  
  European Neuropsychopharmacology
  
  Volume: 29 Issue: 8 Pages: 914-924
- DOI
  10.1016/j.euroneuro.2019.06.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19494, KAKENHI-PROJECT-17H02216, KAKENHI-PROJECT-17K16403
[Journal Article] Loss of cerebellar glutamate transporters EAAT4 and GLAST differentially affects the spontaneous firing pattern and survival of Purkinje cells2018
- Author(s)
  Perkins Emma M、Clarkson Yvonne L、Suminaite Daumante、Lyndon Alastair R、Tanaka Kohichi、Rothstein Jeffrey D、Skehel Paul A、Wyllie David J A、Jackson Mandy
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 27 Issue: 15 Pages: 2614-2627
- DOI
  10.1093/hmg/ddy169
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02216
[Journal Article] Glutamate transporter Slc1a3 mediates inter‐niche stem cell activation during skin growth2018
- Author(s)
  Reichenbach Bettina、Classon Johanna、Aida Tomomi、Tanaka Kohichi、Genander Maria、G?ritz Christian
- Journal Title
  
  The EMBO Journal
  
  Volume: 37 Issue: 9
- DOI
  10.15252/embj.201798280
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02216
[Journal Article] Spinal cord-specific deletion of the glutamate transporter GLT1 causes motor neuron death in mice2018
- Author(s)
  Sugiyama Kaori、Tanaka Kohichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 497 Issue: 2 Pages: 689-693
- DOI
  10.1016/j.bbrc.2018.02.132
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01383, KAKENHI-PROJECT-17H02216, KAKENHI-PROJECT-15J04805
[Journal Article] Region-specific deletions of the glutamate transporter GLT1 differentially affect nerve injury-induced neuropathic pain in mice2018
- Author(s)
  Zhao Zhuoyang、Hiraoka Yuichi、Ogawa Hiroshi、Tanaka Kohichi
- Journal Title
  
  Glia
  
  Volume: 66 Issue: 9 Pages: 1988-1998
- DOI
  10.1002/glia.23452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H02216
[Journal Article] Biased genome editing using the local accumulation of DSB repair molecules system.2018
- Author(s)
  Nakade S, Mochida K, Kunii A, Nakamae K, Aida T, Tanaka K, Sakamoto N, Sakuma T, Yamamoto T
- Journal Title
  
  Nature Communications
  
  Volume: 9(1) Issue: 1 Pages: 3270-3270
- DOI
  10.1038/s41467-018-05773-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07241, KAKENHI-PROJECT-18K19494, KAKENHI-PROJECT-17H01409, KAKENHI-PROJECT-17H02216, KAKENHI-PROJECT-16K07085, KAKENHI-PROJECT-17K15045
[Journal Article] Regulation of visual Wulst cell responsiveness by imprinting causes stimulus-specific activation of rostral cells.2017
- Author(s)
  Nakamori T, Kato T, Sakagami H, Tanaka K, Ohki-Hamazaki H.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 42927-42927
- DOI
  10.1038/srep42927
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01383, KAKENHI-PROJECT-26290021, KAKENHI-PROJECT-15K06717, KAKENHI-PROJECT-15K16571
[Journal Article] Calpain-Dependent Degradation of Nucleoporins Contributes to Motor Neuron Death in a Mouse Model of Chronic Excitotoxicity2017
- Author(s)
  Sugiyama Kaori、Aida Tomomi、Nomura Masatoshi、Takayanagi Ryoichi、Zeilhofer Hanns U.、Tanaka Kohichi
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 37 Issue: 36 Pages: 8830-8844
- DOI
  10.1523/jneurosci.0730-17.2017
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01383, KAKENHI-PROJECT-17H02216, KAKENHI-PROJECT-15J04805
[Journal Article] Association of impaired neuronal migration with cognitive deficits in extremely preterm infants.2017
- Author(s)
  Kubo K, Deguchi K, Nagai T, Ito Y, Yoshida K, Endo T, Benner S, Shan W, Kitazawa A, Aramaki M, Ishii K, Shin M, Matsunaga Y, Hayashi K, Kakeyama M, Tohyama C, Tanaka KF, Tanaka K, Takashima S, Nakayama M, Itoh M, Hirata Y, Antalffy B, Armstrong DD, Yamada K, Inoue K, Nakajima K
- Journal Title
  
  JCI Insight
  
  Volume: 印刷中
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01383
[Journal Article] Association of impaired neuronal migration with cognitive deficits in extremely preterm infants.2017
- Author(s)
  Kubo K, Deguchi K, Nagai T, Ito Y, Yoshida K, Endo T, Benner S, Shan W, Kitazawa A, Aramaki M, Ishii K, Shin M, Matsunaga Y, Hayashi K, Kakeyama M, Tohyama C, Tanaka KF, Tanaka K, Takashima S, Nakayama M, Itoh M, Hirata Y, Antalffy B, Armstrong DD, Yamada K, Inoue K, Nakajima K
- Journal Title
  
  JCI Insight
  
  Volume: 印刷中
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290021
[Journal Article] Region-specific deletions of the glutamate transporter GLT1 differentially affect seizure activity and neurodegeneration in mice2017
- Author(s)
  Sugimoto Junya、Tanaka Moeko、Sugiyama Kaori、Ito Yukiko、Aizawa Hidenori、Soma Miho、Shimizu Tomoko、Mitani Akira、Tanaka Kohichi
- Journal Title
  
  Glia
  
  Volume: 66 Issue: 4 Pages: 777-788
- DOI
  10.1002/glia.23281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19459, KAKENHI-PUBLICLY-16H01383, KAKENHI-PLANNED-26112010, KAKENHI-PROJECT-17H02216, KAKENHI-PROJECT-15J04805
[Journal Article] Effect of geranylgeranylacetone on the protection of retinal ganglion cells in a mouse model of normal tension glaucoma.2016
- Author(s)
  Dong Z, Shinmei Y, Dong Y, Inafuku S, Fukuhara J, Ando R, Kitaichi N, Kanda A, Tanaka K, Noda K, Harada T, Chin S, Ishida S.
- Journal Title
  
  Heliyon
  
  Volume: 2 Issue: 10 Pages: e00191-e00191
- DOI
  10.1016/j.heliyon.2016.e00191
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01383, KAKENHI-PROJECT-15H04999, KAKENHI-PROJECT-16H05484, KAKENHI-PROJECT-26290021, KAKENHI-PROJECT-26462675, KAKENHI-PROJECT-16K11279, KAKENHI-PROJECT-15K20241
[Journal Article] Gene cassette knock-in in mammalian cells and zygotes by enhanced MMEJ.2016
- Author(s)
  Aida T, Nakade S, Sakuma T, Izu Y, Oishi A, Mochida K, Ishikubo H, Usami T, Aizawa H, Yamamoto T, Tanaka K.
- Journal Title
  
  BMC Genomics
  
  Volume: 17 Issue: 1 Pages: 979-979
- DOI
  10.1186/s12864-016-3331-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01383, KAKENHI-PLANNED-26112010, KAKENHI-PROJECT-16J03164, KAKENHI-PROJECT-26290021, KAKENHI-PROJECT-26290070, KAKENHI-PROJECT-26430008, KAKENHI-PROJECT-15K19988, KAKENHI-PROJECT-16K07085, KAKENHI-PROJECT-16K18478
[Journal Article] Posterior cerebellar Purkinje cells in an SCA5/SPARCA1 mouse model are especially vulnerable to the synergistic effect of loss of β-III spectrin and GLAST.2016
- Author(s)
  Perkins EM, Suminaite D, Clarkson YL, Lee SK, Lyndon AR, Rothstein JD, Wyllie DJ, Tanaka K, Jackson M.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 25 Pages: 4448-4461
- DOI
  10.1093/hmg/ddw274
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01383, KAKENHI-PROJECT-26290021
[Journal Article] Positive feedback of NR2B-containing NMDA receptor activity is the initial step toward visual imprinting: a model for juvenile learning.2015
- Author(s)
  Nakamori T, Sato K, Kinoshita M, Kanamatsu T, Sakagami H, Tanaka K, Ohki-Hamazaki H.
- Journal Title
  
  Journal of Neurochemistory
  
  Volume: 132 Issue: 1 Pages: 110-123
- DOI
  10.1111/jnc.12954
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J10484, KAKENHI-PROJECT-24500388, KAKENHI-PROJECT-24500466, KAKENHI-PROJECT-25640025, KAKENHI-PROJECT-26290021, KAKENHI-PROJECT-15K06720
[Journal Article] Valproic acid prevents retinal degeneration in a murine model of normal tension glaucoma2015
- Author(s)
  Kimura, A., Guo, X., Noro, T., Harada, C., Tanaka, K., Namekata, K. and Harada, T
- Journal Title
  
  Neuroscience Letters
  
  Volume: 588 Pages: 108-113
- DOI
  10.1016/j.neulet.2014.12.054
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25430082, KAKENHI-PROJECT-25462766, KAKENHI-PROJECT-25640043, KAKENHI-PROJECT-26290021, KAKENHI-PROJECT-26640048, KAKENHI-PROJECT-26861479
[Journal Article] Cloning-free CRISPR/Cas system facilitates functional cassette knockin in mice2015
- Author(s)
  Aida T, Chiyo K, Usami T, Ishikubo H, Imahashi R, Wada Y, Tanaka K, Sakuma T, Yamamoto T, Tanaka K
- Journal Title
  
  Genome Biol
  
  Volume: 16 Issue: 1 Pages: 87-87
- DOI
  10.1186/s13059-015-0653-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25890014, KAKENHI-PROJECT-26290021, KAKENHI-PLANNED-25117005, KAKENHI-PROJECT-15H03123, KAKENHI-PROJECT-26830131
[Journal Article] Astroglial Glutamate Transporter Deficiency Increases Synaptic Excitability and Leads to Pathological Repetitive Behaviors in Mice.2015
- Author(s)
  Aida T, Yoshida J, Nomura M, Tanimura A, Iino Y, Soma M, Bai N, Ito Y, Cui W, Aizawa H, Yanagisawa M, Nagai T, Takata N, Tanaka KF, Takayanagi R, Kano M, Gotz M, Hirase H, Tanaka K.
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: in press Issue: 7 Pages: 1660-1660
- DOI
  10.1038/npp.2015.26
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23680042, KAKENHI-PUBLICLY-25115726, KAKENHI-PROJECT-25430011, KAKENHI-PROJECT-26290021, KAKENHI-PROJECT-15KT0111, KAKENHI-PLANNED-25117005, KAKENHI-PROJECT-15H03123, KAKENHI-PROJECT-25000015
[Journal Article] Neuronal heterotopias affect the activities of distant brain areas and lead to behavioral deficits2015
- Author(s)
  Kazuhiro Ishii, Ken-ichiro Kubo, Toshihiro Endo, Keitaro Yoshida, Seico Benner, Yukiko Ito, Hidenori Aizawa, Michihiko Aramaki, Akihiro Yamanaka, Kohichi Tanaka, Norio Takata, Kenji Tanaka, Masaru Mimura, Chiahru Tohyama, Masaki Kakeyama, and Kazunori Nakajima
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 35 Issue: 36 Pages: 12432-45
- DOI
  10.1523/jneurosci.3648-14.2015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0111, KAKENHI-PROJECT-26430075, KAKENHI-PROJECT-26640041, KAKENHI-PUBLICLY-15H01293, KAKENHI-PUBLICLY-15H01428, KAKENHI-PUBLICLY-15H01586, KAKENHI-PROJECT-26241016, KAKENHI-PROJECT-15H03123, KAKENHI-PROJECT-25430011, KAKENHI-PROJECT-26290021, KAKENHI-PROJECT-26293046, KAKENHI-PROJECT-15H02355
[Journal Article] Arundic acid attenuates retinal ganglion cell death by increasing glutamate/aspartate transporter expression in a model of normal tension glaucoma.2015
- Author(s)
  Yanagisawa, M., Aida, T., Takeda, T., Namekata, K., Harada, T., Shinagawa, R. and *Tanaka. K.
- Journal Title
  
  Cell Death and Disease
  
  Volume: 6 Issue: 3 Pages: e1693-e1693
- DOI
  10.1038/cddis.2015.45
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25640043, KAKENHI-PROJECT-26290021, KAKENHI-PROJECT-15H04999, KAKENHI-PROJECT-26640048
[Journal Article] A CDC42EP4/septin-based perisynaptic glial scaffold facilitates glutamate clearance.2015
- Author(s)
  Ageta-Ishihara N, Yamazaki M, Konno K, Nakayama H, Abe M, Hashimoto K, Nishioka T, Kaibuchi K, Hattori S, Miyakawa T, Tanaka K, Huda F, Hirai H, Hashimoto K, Watanabe M, Sakimura K, Kinoshita M.
- Journal Title
  
  Nat Commun.
  
  Volume: 6 Issue: 1 Pages: 10090-10090
- DOI
  10.1038/ncomms10090
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350979, KAKENHI-PROJECT-15K18342, KAKENHI-PUBLICLY-15H01297, KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-25117006, KAKENHI-PROJECT-24240048, KAKENHI-PROJECT-15H04274, KAKENHI-PROJECT-26640007, KAKENHI-PROJECT-26290021, KAKENHI-PROJECT-26440095, KAKENHI-PROJECT-25242078, KAKENHI-PUBLICLY-15H01429
[Journal Article] Glial dysfunction in the mouse habenula causes depressive-like behaviors and sleep disturbance.2014
- Author(s)
  Cui W, Mizukami H, Yanagisawa M, Aida T, Nomura M, Isomura Y, Takayanagi R, Ozawa K, Tanaka K, and Aizawa H.
- Journal Title
  
  J. Neurosci.
  
  Volume: 34 Issue: 49 Pages: 16273-16285
- DOI
  10.1523/jneurosci.1465-14.2014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390247, KAKENHI-PLANNED-26112010, KAKENHI-PROJECT-26290021, KAKENHI-PROJECT-26430008
[Journal Article] Neuronal glutamate transporters regulate glial excitatory transmission2012
- Author(s)
  Tsai, M-C., Tanaka, K., Overstreet-Wadiche, L., Wadiche, JI.
- Journal Title
  
  J Neurosci
  
  Volume: 32 Pages: 1528-1535
- Data Source
  KAKENHI-PROJECT-21300137
[Journal Article] RBP-J promotes the maturation of neuronal progenitors2011
- Author(s)
  Komine, O., Nagaoka, M., Hiraoka, Y., Hoshino, M., Kawaguchi, Y., Pear, E. S., Tanaka, K.
- Journal Title
  
  Dev Bio
  
  Volume: 354 Pages: 44-54
- Data Source
  KAKENHI-PROJECT-21300137
[Journal Article] Zones of enhanced glutamate release from climbing fibers in the mammalian cerebellum2010
- Author(s)
  Paukert, M., Huang, Y. H., Tanaka, K., Rothstein, J. D., Bergles, D. E.
- Journal Title
  
  J Neurosci
  
  Volume: 30 Pages: 7290-7299
- Data Source
  KAKENHI-PROJECT-21300137
[Journal Article] Development of the mouse amygdala as revealed by enhanced green fluorescent protein gene transfer by means of in utero electroporation2009
- Author(s)
  Soma, M., Aizawa, H., Ito, Y., Maekawa,M., Osumi, N., Nakahira, E., Okamoto,H., Tanaka, K., Yuasa, S.
- Journal Title
  
  J Comp Neurol 513
  
  Pages: 113-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300127
[Journal Article] グルタミン酸トランスポーターと精神神経疾患2008
- Author(s)
  相田知海、田中光一
- Journal Title
  
  遺伝子医学MOOK 12
  
  Pages: 212-217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300127
[Journal Article] アストロサイトにおけるグルタミン酸トランスポーターの機能2008
- Author(s)
  田中光一
- Journal Title
  
  Brain and Nerve 59
  
  Pages: 677-688
- Data Source
  KAKENHI-PROJECT-19300127
[Journal Article] Loss of Glial Glutamate and Aspartate Transporter(Excitatory Amino Acid Transporter 1)Causes Locomotor Hyperactivity and Exaggerated Responses to Psychotomimetics : Rescus by Haloperidol and Metabotropic Glutamate 2/3 Agonist2008
- Author(s)
  Karlsson, RM., Tanaka, K., Heilig, M., Holmes, A.
- Journal Title
  
  Biol Psychiatry 64
  
  Pages: 810-814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300127
[Journal Article] 神経幹細胞の分化過程のメカニズム2008
- Author(s)
  田中光一
- Journal Title
  
  分子精神医学 7
  
  Pages: 86-91
- Data Source
  KAKENHI-PROJECT-19300127
[Journal Article] Glutamate transporters regulate lesion-induced plasticity in the developing somatosensory cortex2008
- Author(s)
  Takasaki, C., Okada, R., Mitani, A., Fukaya, M., Yamasaki, M., Fujihara, Y., Shirakawa, T., Tanaka, K., Watanabe, M.
- Journal Title
  
  J Neurosci 28
  
  Pages: 4995-5006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300127
[Journal Article] グルタミン酸トランスポーターの中枢神経系における役割2008
- Author(s)
  相田知海、田中光一
- Journal Title
  
  Clinical Neuroscience 26
  
  Pages: 1072-1076
- Data Source
  KAKENHI-PROJECT-19300127
[Journal Article] Activation of cholecystokinin neurons in the dorsal pallium of the telencephalon is indispensable for the acquisition of chick imprinting behavior2007
- Author(s)
  Maekawa, F., Nakamori, T., Uchimura,M., Fujiwara, K., Yada, T., Tsukahara,S., Kanamatsu, T., Tanaka, K., Ohki-Hamazaki, H
- Journal Title
  
  J Neurochem 102
  
  Pages: 645-1657
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300127
[Journal Article] Contribution of glutamate transporter GLT-1 to removal of synaptically released glutamate at climbing fiber-Purkinje cell synapses2007
- Author(s)
  Takatsuru, Y., Iino, M., Tanaka, K., Ozawa, S
- Journal Title
  
  Neurosci Lett 420
  
  Pages: 85-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300127
[Journal Article] The potential role of glutamate transporters in the pathogenesis of normal tension glaucoma2007
- Author(s)
  Harada, T., Harada, C., Nakamura, K.,Qua, H-M.A., Okumura, A., Namekata, K., Saeki, T., Aihara, M., Yoshida, H., Mitani, A., Tanaka, K
- Journal Title
  
  J Clin Invest 117
  
  Pages: 1763-1770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300127
[Journal Article] characterization of GLT1(+/-)mice as a model of mild glutamatergic hyperfunction2007
- Author(s)
  Kiryk, A., Aida, T., Tanaka, K., Banerjee, P., Wilczynski, G.M., Meyza,K., Knapska, E., Filipkowaski, R.K., Kaczmarek, L., Danysz, W. Behavioral
- Journal Title
  
  Neurotox Res 13
  
  Pages: 19-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300127
[Journal Article] The monolayer formation of Bergmann glial cells is regulated by Notch/RBP-J signaling2007
- Author(s)
  Komine, O., Nagaoka, M., Watase, K., Gutmann, D.H., Tanigaki, K., Honjo, T., Radtke, F., Saito, C., Chiba, S., Tanaka, K.
- Journal Title
  
  Dev Biol 311
  
  Pages: 238-250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300127
[Journal Article] Proteomics in retina of Excitory Acid Carrier 1(EAAC1)knockout mice2007
- Author(s)
  Tanimoto, S., Suzuki, M., Ue, T., Okumichi, H., Aoyama, H., Souchelnytskyi, S., Tanaka, K., Agarwal, N., Mishima, H.K., Kanamoto, T.
- Journal Title
  
  Proteome Science 5
  
  Pages: 13-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300127
[Journal Article] activation of metabotropic glutamate receptors in cerebellar Purkinje cells in glutamate transporter EAAT4-deficient mice2007
- Author(s)
  Nikkuni, O., Takayasu, Y., Iino, M., Tanaka, K., Ozawa, S. Facilitated
- Journal Title
  
  Neurosci Res 59
  
  Pages: 296-303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300127
[Journal Article] Glutamate transporter in retinal Muller cells from glutamate/aspartate transporter (GLAST) knockout mice.2005
- Author(s)
  Sarthy, V.P., Pignataro, L., Pannicke, T., Weick, M., Reichenbach, A., Harada, T., Tanaka K., Marc, R.
- Journal Title
  
  Glia 49
  
  Pages: 184-196
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Journal Article] Antibiotics rescue neurons from glutamate attack2005
- Author(s)
  Tanaka K
- Journal Title
  
  Trends Mol Med. 11
  
  Pages: 259-262
- Data Source
  KAKENHI-PROJECT-16047206
[Journal Article] Role of Neurotrophin-4/5 in Neural Cell Death during Retinal Development and Ischemic Retinal Injury in Vivo.2005
- Author(s)
  Harada, C., Harada, T., Quah, H-M A., Namekata, K., Yoshida, K., Ohno, S., Tanaka K., Parada, L.F.
- Journal Title
  
  Invest Ophthalmol Vis Sci 46
  
  Pages: 669-673
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Journal Article] Astrocyte glutamate transporters regulate metabotropic glutamate receptor-mediated excitation of hippocampal interneurons.2004
- Author(s)
  Huang, Y.H., Tanaka, K., Rothstein J.D., Bergles D.E.
- Journal Title
  
  J.Neurosci. 24
  
  Pages: 4498-4509
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Journal Article] The contribution of a glial glutamate transporter to GABA synthesis in the retina.2004
- Author(s)
  Sarthy, V.P., Pignataro, L., Marc, R., Tanaka, K.
- Journal Title
  
  NeuroReport 15
  
  Pages: 1895-1898
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Journal Article] The glutamate transporter GLT1a is expressed in excitatory axon terminals of mature hippocampal neurons.2004
- Author(s)
  Chen, W., Mahadomrongkul, V., Berger, U.V., Bassan, M., DeSilva, T., Tanaka K., Irwin, N., Aoki, C., Rosenberg, P.A.
- Journal Title
  
  J.Neurosci. 24
  
  Pages: 1136-1148
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Journal Article] Distributions of two chicken bonbesin receptors, bombesin receptor subtype-3.5 (chBRS-3.5) and gastrin-releasing peptide receptor (chGRP-R) mRNA's in chicken telencephalon.2004
- Author(s)
  Maekawa, F., Tsukahara, S., Tanaka K., Ohki-Hamazaki, H.
- Journal Title
  
  Neuroscience 125
  
  Pages: 569-582
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Journal Article] Leptin resistance and enhancement of feeding facilitation by melanin-concentrating hormone in mice lacking bombesin receptor subtype-3.2004
- Author(s)
  Maekawa, E, Quah, H.-M.A., Tanaka, K., Ohki-Hamazaki, H.
- Journal Title
  
  Diabetes 53
  
  Pages: 570-576
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Journal Article] Diverse NF-kB expression in epiretinal membranes after human diabetic retinopathy and proliferative vitreoretinopaty.2004
- Author(s)
  Harada, C., Harada, T., Mitamura, Y., Quah, H-M.A., Ohtsuka, K., Kotake, S., Ohno, S., Wada, K., Takeuchi, S., Tanaka K.
- Journal Title
  
  Mol.Vision 10
  
  Pages: 31-36
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Journal Article] Retinal glucose metabolism in mice lacking the L-glutamate/aspartate transporter.2004
- Author(s)
  Sarthy, V.P., Dudley, V.J., Tanaka, K.
- Journal Title
  
  Vis.Neurosci. 21
  
  Pages: 637-643
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Journal Article] Role of ubiquitin carboxy terminal hydrolase-L1 in neural cell apoptosis induced by ischemic retinal injury in vivo.2004
- Author(s)
  Harada, T., Harada, C., Wang, Y-U., Osaka, H., Amanai, K., Tanaka K., Takizawa, S., Setsuie, R., Sakurai, M., Sato, Y., Noda, M., Wada, K.
- Journal Title
  
  Am.J.Pathol. 164
  
  Pages: 59-64
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Journal Article] Climbing fiber activation of EAAT4 transporters and kainite receptors in cerebellar Purkinje cells.2004
- Author(s)
  Huang, Y., Dykes Hoberg, M., Tanaka.K., Rothstein J.D., Bergles D.E.
- Journal Title
  
  J.Neurosci. 24
  
  Pages: 103-111
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Journal Article] Potential role of glial cell line-derived neurotrophic factor receptors in Muller glial cells during light-induced retinal degeneration.2003
- Author(s)
  Harada, C., Harada, T., Quah, H.-M.A., Maekawa, F., Yoshida, K., Ohno, S., Wada, K., Parada, L.F., Tanaka, K.
- Journal Title
  
  Neuroscience 122
  
  Pages: 229-235
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Journal Article] Glial glutamate transporters mediate a functional metabolic crosstalk between neurons and astrocytes in the mouse developing cortex.2003
- Author(s)
  Voutsinos-Porche, B., Bonvento, G., Tanaka.K., Welker, E., Chatton, J.-Y., Magistretti, P.J., Pellerin, L.
- Journal Title
  
  Neuron 37
  
  Pages: 275-286
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Journal Article] Long-term potentiation in the hippocampal CA1 area and dentate gyrus plays different roles in spatial learning.2003
- Author(s)
  Okada, T., Yamada, N., Tsuzuki, K., Horikawa, PM., Tanaka, K., Ozawa, S.
- Journal Title
  
  Eur.J.Neurosci. 17
  
  Pages: 341-349
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Journal Article] Functional changes of glial glutamate transporter GLT-1 during ischemic : An in vivo study in the hippocampal CA1 of normal mice and of mutant mice lacking GLT-1.2003
- Author(s)
  Mitani, A., Tanaka, K.
- Journal Title
  
  J.Neurosci. 23
  
  Pages: 7176-7182
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Journal Article] NF-kB in epiretinal membranes after human diabetic retinopathy.2003
- Author(s)
  Mitamura, Y., Harada, T., Harada, C., Ohtsuka, K., Kotake, S., Ohno, S., Tanaka, K., Takeuchi, S., Wada, K.
- Journal Title
  
  Diabetologia 46
  
  Pages: 699-703
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Journal Article] Glial glutamate transporters and maturation of the mouse somatosensory cortex.2003
- Author(s)
  Voutsinos-Porche, B., Knott, G., Tanaka, K., Quairiaux, C., Welker, E., Bonvento, G.
- Journal Title
  
  Cereb.Cortex 13
  
  Pages: 1110-1121
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Journal Article] Expression of GLAST in the developing mouse cochlea.2003
- Author(s)
  Jin, Z.H., Kikuchi, T, Tanaka, K., Kobayashi, T.
- Journal Title
  
  Tohoku J.Exp.Med. 200
  
  Pages: 137-144
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Journal Article] Molecular cloning and characterization of avian bombesin-like peptide receptors : New tools for investigating molecular basis for ligand selectivity.2003
- Author(s)
  Iwabuchi, M., Ui-Tei, K., Yamada, Y., Matsuda, Y., Sakai, Y., Tanaka.K., Ohki-Hamazaki, H.
- Journal Title
  
  Brit.J.Pharmacol. 139
  
  Pages: 555-566
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Journal Article] Assessment of glutamate transporter GLAST(EAAT1)deficient mice for phenotypes relevant to the negative and executive/cognitive symptoms of schizophrenia
- Author(s)
  Karlsson, RM., Tanaka, K., Saksida,LM., Bussey, TJ., Heilig, M., Holmes, A.
- Journal Title
  
  Neuropsychopharmacology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300127
[Patent] 簡便で高効率の遺伝子改変非ヒト哺乳動物の作製方法2014
- Inventor(s)
  田中光一、相田知海、和田悠作
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学、株式会社ファスマック
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-232963
- Filing Date
  2014-11-17
- Data Source
  KAKENHI-PROJECT-26290021
[Patent] グルタミン酸トランスポーターGLAST機能欠損マウス2004
- Inventor(s)
  田中光一
- Industrial Property Rights Holder
  田中光一
- Filing Date
  2004-04-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Patent] グルタミン酸トランスポーターGLAST機能欠損マウス2003
- Inventor(s)
  田中光一
- Industrial Property Rights Holder
  田中光一
- Filing Date
  2003-04-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14208092
[Presentation] Neuronal heterotopias affect the activities of distant brain areas and lead to behavioral deficits2015
- Author(s)
  Kazuhiro Ishii, Ken-ichiro Kubo1, Toshihiro Endo, Keitaro Yoshida, Seico Benner, Yukiko Ito, Hidenori Aizawa, Michihiko Aramaki, Akihiro Yamanaka, Kohichi Tanaka, Norio Takata, Kenji F. Tanaka, Masaru Mimura, Chiharu Tohyama, Masaki Kakeyama, and Kazunori Nakajima
- Organizer
  Neuroscience 2105
- Place of Presentation
  シカゴ（イリノイ州・米国）
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290021
[Presentation] Cloning-free genome editing in mice2015
- Author(s)
  Kohichi Tanaka, Tomomi Aida, Keiho Chiyo, Takako Usami, Harumi Ishikubo, Risa Imahashi, Yusaku Wada, Kenji F. Tanaka, Tetsushi Sakuma, Takashi Yamamoto
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸ポートアイランド（神戸市・兵庫県）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26290021
[Presentation] Loss of glial glutamate transporters induces motor neuron death in mice.2015
- Author(s)
  Kaori Sugiyama, Tomomi Aida, Masatoshi Nomura, Ryoichi Takayanagi, Kohichi Tanaka
- Organizer
  第38回日本分子生物学会
- Place of Presentation
  神戸ポートアイランド（神戸市・兵庫県）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26290021
[Presentation] Analyses of the pathological roles of the altered brain cytoarchitectures with ectopic neurons2015
- Author(s)
  Ken-ichiro Kubo, Kazuhiro Ishii, Toshihiro Endo, Keitaro Yoshida, Seico Benner, Yukiko Ito, Hidenori Aizawa, Michihiko Aramaki, Akihiro Yamanaka, Kohichi Tanaka, Norio Takata, Kenji F. Tanaka, Masaru Mimura, Chiharu Tohyama, Masaki Kakeyama, and Kazunori Nakajima
- Organizer
  第58回日本神経化学会大会
- Place of Presentation
  大宮ソニックシティ（さいたま市・埼玉県）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-26290021
[Presentation] Loss of glial glutamate transporter GLT-1 during development causes behavioral abnormalities relevant to the symptoms of schizophrenia2015
- Author(s)
  Kaori Sugiyama, Daiki Nagaoka, Tomomi Aida, Kenji F Tanaka, Shigeyoshi Itohara, Kohichi Tanaka
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸ポートアイランド（神戸市・兵庫県）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26290021
[Presentation] NR2B/NR1依存的な神経可塑的変化が幼少期の学習効率を上げている2014
- Author(s)
  中森智啓、佐藤勝重、木下雅恵、田中光一、浜崎浩子
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-11
- Data Source
  KAKENHI-PROJECT-26290021
[Presentation] グルタミン酸トランスポーターの欠損は過剰な繰り返し行動を引き起こす2014
- Author(s)
  相田知海、吉田純一、野村政壽、谷村あさみ、飯野祐介、相馬美歩、Bai Ning、伊藤亨子、Cui Wangpeng、相澤秀紀、永井てるみ、高田則雄、髙栁涼一、狩野方伸、Magdalena Götz、平瀬肇、田中光一
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PROJECT-26290021
[Presentation] グリア型グルタミン酸トランスポータGLT-1は皮質拡延性抑制に対する感受性を制御する2014
- Author(s)
  豊田早織、孫偉楠、伊藤亨子、崔万鵬、相田知海、柳澤美智子、野村政壽、高柳涼一、田中光一、相澤秀紀
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PROJECT-26290021
[Presentation] Glial glutamate transporter GLT-1 determines sensitivity to the cortical spreading depression2014
- Author(s)
  Hidenori Aizawa, Weinan Sun, Yukiko Ito, Saori Toyoda, Wangpeng Cui, Tomomi Aida, Masatoshi Nomura, Michiko Yanagisawa, Ryoichi Takayanagi, Kohichi Tanaka
- Organizer
  Annual Meeting of the Society for Neuroscience
- Place of Presentation
  Washington, DC（米国）
- Year and Date
  2014-11-16
- Data Source
  KAKENHI-PROJECT-26290021
[Presentation] グリア型グルタミン酸トランスポーターGLT1の脳部位特異的機能解析2014
- Author(s)
  杉本潤哉、伊藤亨子、相馬美歩、崔万鵬、三谷章、野村政壽、高柳涼一、相澤秀紀、田中光一
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-11
- Data Source
  KAKENHI-PROJECT-26290021
[Presentation] 機能カセットノックインマウスのためのCRISPR/Casを用いたin vivoゲノム編集2014
- Author(s)
  相田知海、張景閎、佐久間哲史、宇佐美貴子、石久保春美、今橋里沙、田中謙二、山本卓、田中光一
- Organizer
  日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-26290021
[Presentation] 高速・高効率in vivoゲノム編集によるノックインマウス作出2014
- Author(s)
  今橋里沙、相田知海、張景ほう、佐久間哲史、宇佐美貴子、石久保春美、Pawel Obrocki、山本卓、田中光一
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PROJECT-26290021
[Presentation] グルタミン酸トランスポーターのうつ様行動における役割2014
- Author(s)
  相澤秀紀、崔万鵬、水上浩明、柳澤美智子、相田知海、野村政壽、礒村宜和、高柳涼一、小澤敬也、田中光一
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PROJECT-26290021
[Presentation] Enhancement of glutamate clearance via cortical glial glutamate transport (GLT-1) induced resiliency to stress2014
- Author(s)
  Mouna Banasr, Ashley E Lepack, Jaime Maldonado-Aviles, Carly L Kiselycznyk, Vanja Duric, Jie Zhang, Stacey Wilber, Kohichi Tanaka, PRalph J DiLeone, Ronald S Duman, Gerard Sanacora
- Organizer
  Annual Meeting of the Society for Neuroscience
- Place of Presentation
  Washington, DC（米国）
- Year and Date
  2014-11-19
- Data Source
  KAKENHI-PROJECT-26290021
[Presentation] Glial dysfunction in the mouse habenula causes depressive behaviors and sleep disturbance2014
- Author(s)
  Wangpeng Cui, Hiroaki Mizukami, Michiko Yanagisawa, Tomomi Aida, Masatoshi Nomura, Yoshikazu Isomura, Ryoichi Takayanagi, Keiya Ozawa, Kohichi Tanaka, Hidenori Aizawa
- Organizer
  Annual Meeting of the Society for Neuroscience
- Place of Presentation
  Washington, DC（米国）
- Year and Date
  2014-11-19
- Data Source
  KAKENHI-PROJECT-26290021
[Presentation] グリア型グルタミン酸トランスポーターGLT-1を前頭前野特異的に欠損したマウスは統合失調症様の行動異常を引き起こす2014
- Author(s)
  橋本真理子、相澤秀紀、相田知海、崔万鵬、水上浩明、小澤敬也、野村政壽、高柳涼一、田中光一
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PROJECT-26290021
[Presentation] Deficiency of glutamate transporter in astrocyte increases brain excitability and induces Tourette’s Syndrome-like excessive repetitive behaviours in mice2014
- Author(s)
  Tomomi Aida, Junichi Yoshida, Masatoshi Nomura, Asami Tanimura, Yusuke Iino, Miho Soma, Ning Bai, Yukiko Ito, Wangpeng Cui, Hidenori Aizawa, Terumi Nagai, Norio Takata, Ryoichi Takayanagi, Masanobu Kano, Magdalena Götz, Hajime Hirase, Kohichi Tanaka
- Organizer
  Annual Meeting of the Society for Neuroscience
- Place of Presentation
  Washington, DC（米国）
- Year and Date
  2014-11-18
- Data Source
  KAKENHI-PROJECT-26290021
[Presentation] グルタミン酸トランスポーターGLASTのヒトレアバリアントは網膜神経節細胞の脆弱性にin vivoで寄与する2014
- Author(s)
  今橋里沙、相田知海、柳澤美智子、佐久間哲史、宇佐美貴子、石久保春美、山本卓、田中光一
- Organizer
  日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-26290021
[Presentation] 脊髄におけるグリア型グルタミン酸トランスポーターの欠損はALS様症状を引き起こす2014
- Author(s)
  杉山香織、相田知海、野村政壽、高柳涼一、田中光一
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PROJECT-26290021
[]

1. MITANI Akira (50200043)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 和田圭司 (70250222)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. OKADA Takashi (00242082)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. HASEGAWA Mamoru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KAKU Gyourei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. YOSHIDA Keitaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. KATO Shigeki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 小澤敬也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 佐久間哲史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 田中謙二

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 松井広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 相澤秀紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 伊佐正

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 高田則雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 野田幸裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 行方和彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 石田紗恵子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 阿部学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 坂本尚昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanaka Kohichi 田中 光一

TAKANO Kohichi 田中 光一

田中 光一 タナカ コウイチ

Research Projects

Research Products

Co-Researchers

Functional reconstruction of neural circuits using differentiation of astrocytes into neuronsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Recording neuronal activities onto DNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Circuit-specific neuron-astrocyte cross-talk in the striatumPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アストロサイトによる体温調節機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of astrocyte heterogeneityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms of subcellular synapse organization in cerebellar Purkinje neuronsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

抑制性神経前駆細胞の実体解明と神経分化におけるノッチシグナルの役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

グリア伝達物質の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

グルタミン酸トランスポーターの発現細胞による機能的差異Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The differentiation and function of molecular-layer interneurons in the cerebellumPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

グリア伝達物質の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脳の発達におけるグルタミン酸トランスポーターの役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脳の発達におけるグルタミン酸トランスポーターの役割Principal Investigator

Principal Investigator

Tanaka Kohichi 田中光一

TAKANO Kohichi 田中光一

田中光一タナカコウイチ