Matsumoto Tomohiro 松本智裕

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MATSUMOTO Tomohiro 松本智裕

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Researcher Number	80212223
Other IDs
Affiliation (Current)	2025: 京都大学, 生命科学研究科, 教授
Affiliation (based on the past Project Information) *help	2020 – 2022: 京都大学, 生命科学研究科, 教授 2010 – 2016: 京都大学, 放射線生物研究センター, 教授 2011: 京都大学, 放射線生物研究センター, センター長 2002 – 2007: 京都大学, 放射線生物研究センター, 教授
Review Section/Research Field	Principal Investigator Biological Sciences / Risk sciences of radiation/Chemicals / Basic Section 43010:Molecular biology-related / Cell biology / Risk sciences of radiation and chemicals / Biological Sciences Except Principal Investigator Functional biochemistry
Keywords	Principal Investigator スピンドルチェックポイント / Mad2 / セントロメア / クロマチン / p31comet / 染色体 / 有糸分裂期 / DNCI / 損傷修復 / Cenp-A … More / 細胞周期 / 減数分裂 / Cenp-Aヒストン / Cenp-A ヒストン / 分裂酵母 / CENP-A / spindle checkpoint / mitosis / EB1 / Mad1 / ユビキチン化 / 紡錘糸 / 動原体 / 染色体安定性 / 放射線感受性 / 酵母 / 染色体凝縮 / テロメア / プロテアソーム / 均等配分 / ゲノム安定性 / 均等分配 / チェックポイント / 紡錘糸阻害剤 / 染色体配分 / オーロラキナーゼ / アポトーシス / 染色体分配 / p53 / DNA損傷 / 放射線 … More Except Principal Investigator Medaka / Atomic force microscopy / DNA repair / Kinetochore / Telomere / Mitosis / Cell cycle / Chromosome / 組み換え / 修復 / 細胞周期 / 生命継承 / 細胞分裂周期 / 原子間力顕微鏡 / テロメア / DNA修復 / 酵母 / 紡錘体 / 原動体 / 染色体 / アミノ酸透過酵素 / ユビキチンリガーゼ / TSC / 栄養源枯渇 / シグナル伝達 / 細胞情報伝達機構 Less

Analysis of the mechanism of centtome disassemblyPrincipal Investigator
- Principal Investigator
  
  Matsumoto Tomohiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Kyoto University
核膜アンカーに依存したセントロメアクロマチン制御機構の解析Principal Investigator
- Principal Investigator
  
  松本智裕
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Impact and response to DNA damage in mitosisPrincipal Investigator
- Principal Investigator
  
  Matsumoto Tomohiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyoto University
Analysis of Cenp-A and HJURP at damage sitesPrincipal Investigator
- Principal Investigator
  
  MATSUMOTO Tomohiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
スピンドルチェックポイントの解除機構の解明Principal Investigator
- Principal Investigator
  
  松本智裕
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Regulation of genome stability undernutritionalstarvation
- Principal Investigator
  
  NAKASE Yukiko
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  Kyoto University
ゲノム安定性を維持するスピンドルチェックポイントの分子機構Principal Investigator
- Principal Investigator
  
  松本智裕
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
有糸分裂期の放射線応答Principal Investigator
- Principal Investigator
  
  松本智裕
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
The signal cascade of the spindle checkpointPrincipal Investigator
- Principal Investigator
  
  MATSUMOTO Tomohiro
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
Maintenance and Inheritance of Diverse Life by Chromosome Dynamics
- Principal Investigator
  
  YANAGIDA Mitsuhiro
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for COE Research
- Research Institution
  Kyoto University

All 2015 2014 2012 2011 2010 2009 2008 2007 2006 2005 2004 2002 Other

All Journal Article Presentation Book

[Book] Molecular mechanisms and function of the spindle checkpoint, a puardian of the chromosome stability, in Polyploidization and Cancer2008
- Author(s)
  Daisuke Ito and Tomohiro Matsumoto
- Total Pages
  12
- Publisher
  Landes Bioscience
- Data Source
  KAKENHI-PROJECT-17013044
[Book] The dream of every chromosome; equal segregation for a healthy life of the host. Genome Instability and Cancer Development, Chapter3.32006
- Author(s)
  Matsumoto, T., et al.
- Total Pages
  30
- Publisher
  Springer
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13CE2006
[Book] The dream of every chromosome ; equal segregation for a healthy life of the host2005
- Author(s)
  Matsumoto, T., Yanagida, M.
- Publisher
  Genome Instability and Cancer Development, Kluwer Academic Publishers(印刷中)
- Data Source
  KAKENHI-PROJECT-13CE2006
[Book] The dream of every chromosome ; equal segregation for a healthy life of the host. Genome Instability and Cancer Development, in Advances in Experimental Medicine and Biology2005
- Author(s)
  Matsumoto, T., et al.
- Total Pages
  30
- Publisher
  Springer
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13CE2006
[Book] Genome Instability and Cancer Development2005
- Author(s)
  Matsumoto, T, Yanagida, M.
- Publisher
  Kluwer Academic Publishers
- Data Source
  KAKENHI-PROJECT-13CE2006
[Book] The dream of every chromosome ; equal segregation for a healthy life of the host. Genome Instability and Cancer Development, in Advances in Experimental Medicine and Biology2005
- Author(s)
  Matsumoto, T., et al.
- Total Pages
  30
- Publisher
  Springer
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15370085
[Book] Genome Instability and Cancer Development(The dream of every chromosome ; equal segregation for a healthy life of the host)
- Author(s)
  Matsumoto, T., Yanagida, M.
- Publisher
  Kluwer Academic Publishers(in press)
- Data Source
  KAKENHI-PROJECT-15370085
[Journal Article] The 19S proteasome subunit Rpt3 regulates distribution of CENP-A by associating with centromeric chromatin2014
- Author(s)
  T. Kitagawa, K. Ishii, K. Takeda, T. Matsumoto
- Journal Title
  
  Nature Communications
  
  Volume: 5 Issue: 1 Pages: 3597-3597
- DOI
  10.1038/ncomms4597
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22125001, KAKENHI-PLANNED-22125004, KAKENHI-PROJECT-24370003, KAKENHI-PROJECT-24651047, KAKENHI-PROJECT-25440093, KAKENHI-PROJECT-25650122, KAKENHI-PUBLICLY-26116508, KAKENHI-PROJECT-26650124
[Journal Article] Centromere-tethered Mpsl pombe homolog (Mphl) kinase is a sufficient marker for recruitment of the spindle checkpoint protein Bubl, but not Madl2012
- Author(s)
  Ito D, Saito Y, Matsumoto T
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 109 Issue: 1 Pages: 209-214
- DOI
  10.1073/pnas.1114647109
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22019020
[Journal Article] A mutation of the fission yeast EB1 overcomes negative regulation by phosphorylation and stabilizes microtubules2012
- Author(s)
  Iimori, M.
- Journal Title
  
  Exp Cell Res
  
  Volume: 318 Issue: 3 Pages: 262-275
- DOI
  10.1016/j.yexcr.2011.11.006
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-20114001, KAKENHI-PLANNED-20114002, KAKENHI-PLANNED-20114006, KAKENHI-PUBLICLY-22019020, KAKENHI-PROJECT-22370074, KAKENHI-PROJECT-23247003, KAKENHI-PROJECT-23501267, KAKENHI-PROJECT-24370071
[Journal Article] Intracellular trafficking and ubiquitination of the Schizosac charomyces pombe amino acid2012
- Author(s)
  Nakase M, Nakase Y, ChardwiriyapreechaS, Kakinuma Y, Matsumoto T, Takegawa K
- Journal Title
  
  Microbiology
  
  Volume: 158(Pt 3) Issue: 3 Pages: 659-73
- DOI
  10.1099/mic.0.053389-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19657039
[Journal Article] Distinctive responses to nitrogen starvation in the dominant active mutants of the fission yeast Rheb GTPase2009
- Author(s)
  Murai T, Nakase Y, Fukuda K, ChikashigeY, Tsutsumi C, Hiraoka Y, Matsumoto T
- Journal Title
  
  Genetics
  
  Volume: 183(2) Issue: 2 Pages: 517-27
- DOI
  10.1534/genetics.109.105379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19657039
[Journal Article] Distinctive responses to nitrogen starvation in the dominant active mutants of the fission yeast Rheb GTPase2009
- Author(s)
  Tomoka Murai, Yukiko Nakase, Keiko Fukuda, Yuji Chikashige, Chihiro Tsutsumi, Yasushi Hiraoka, Tomohiro Matsumoto
- Journal Title
  
  Genetics 20
  
  Pages: 517-527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19657039
[Journal Article] A defect in protein farnesylation suppresses a loss of Schizosaccharmyces pombe tsc2+, a homolog of human gene predisposing tuberous sclerosis complex (TSC)2006
- Author(s)
  Nakase, Y., Fukuda, K., Chikashige, Y., Tsutsumi, C., Morita, D., Kawamoto, S., Ohnuki, M., Hiraoka, Y., Matsumoto, T
- Journal Title
  
  Genetics 173
  
  Pages: 569-578
- Data Source
  KAKENHI-PROJECT-17013044
[Journal Article] Low Concentrations of Taxol Cause Mitotic Delay Followed by Premature Dissociation of p55CDC from Mad2 and BubR1 and Abrogation of the Spindle checkpoint, Leading to Aneuploidy.2005
- Author(s)
  Ikui AE, Yang CPH, Matsumoto T, Horwitz SB
- Journal Title
  
  Cell Cycle 4
  
  Pages: 1385-1388
- Data Source
  KAKENHI-PROJECT-17013044
[Journal Article] The dream of every chromosome ; equal segregation for a healthy life of the host.2005
- Author(s)
  Matsumoto, T., et al.
- Journal Title
  
  Genome Instability and Cancer Development, in Advances in Experimental Medicine and Biology, Springer, Nigg, Erich A. (Ed.) Vol. 570
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13CE2006
[Journal Article] Low Concentrations of Taxol Cause Mitotic Delay Followed by Premature Dissociation of p55CDC from Mad2 and BubR1 and Abrogation of the Spindle checkpoint, Leading to Aneuploidy.2005
- Author(s)
  Ikui AE, Yang CPH, Matsumoto T, Horwitz SB
- Journal Title
  
  Cell Cycle 4
  
  Pages: 1385-1388
- Data Source
  KAKENHI-PROJECT-15370085
[Journal Article] Low Concentrations of Taxol Cause Mitotic Delay Followed by Premature Dissociation of p55CDC from Mad2 and BubR1 and Abrogation of the Spindle checkpoint, Leading to Aneuploidy.2005
- Author(s)
  Ikui AE, Yang CPH, Matsumoto T, Horwitz SB.
- Journal Title
  
  Cell Cycle 4
  
  Pages: 1385-1388
- Data Source
  KAKENHI-PROJECT-13CE2006
[Journal Article] Conformation-specific binding of p31^<comet> to Mad2 antagonizes the function of Mad2 in the spindle checkpoint.2004
- Author(s)
  Guohong Xia, Xuelian Luo, Toshiyuki Habu, Josep Rizo, Tomohiro Matsumoto, Yu, H.
- Journal Title
  
  EMBO J. 23
  
  Pages: 3133-3143
- Data Source
  KAKENHI-PROJECT-15370085
[Journal Article] Conformation-specific binding of p31^<comet> to Mad2 antagonizes the function of Mad2 in the spindle checkpoint.2004
- Author(s)
  Guohong Xia, Xuelian Luo, Toshiyuki Habu, Josep Rizo, Tomohiro Matsumoto, Yu, H.
- Journal Title
  
  EMBO J. 23
  
  Pages: 3133-3143
- Data Source
  KAKENHI-PROJECT-13CE2006
[Journal Article] Conformational signaling by Mad2 in the mitotic spindle checkpoint2004
- Author(s)
  Luo X., Tang Z., Xia, G., Wassmann X., Matsumoto T., Rizo, J., Yu H
- Journal Title
  
  Nature Structural & Molecular Biology 11
  
  Pages: 338-345
- Data Source
  KAKENHI-PROJECT-13CE2006
[Journal Article] Conformational signaling by Mad2 in the mitotic spindle checkpoint2004
- Author(s)
  Luo X., Tang Z., Xia, G., Wassmann K., Matsumoto T., Rizo, J., Yu H
- Journal Title
  
  Nature Structural & Molecular Biology 11
  
  Pages: 338-345
- Data Source
  KAKENHI-PROJECT-15370085
[Journal Article] Role of fission yeast Tsc1-Tsc2 complex in signaling and transport across cell membrane.2002
- Author(s)
  Matsumoto, S., et al.
- Journal Title
  
  Genetics 161
  
  Pages: 1053-1063
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13CE2006
[Journal Article] Role of fission yeast Tscl -Tsc2 complex in signaling and transport across cell membrane.2002
- Author(s)
  Matsumoto, S., et al.
- Journal Title
  
  Genetics 161
  
  Pages: 1053-1063
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13CE2006
[Journal Article] The 19S proteasome subunit Rpt3 regulates distribution of CENP-A by associating with centromeric chromatin
- Author(s)
  Teppei Kitagawa, Kojiro Ishii, Kojiro Takeda and Tomohiro Matsumoto.
- Journal Title
  
  Nature Communications
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-24651047
[Presentation] Cnp1の局在制御に関与するCnp3の機能解析2015
- Author(s)
  須摩美智子、松本智裕
- Organizer
  酵母遺伝学フォーラム
- Place of Presentation
  広島大学東広島キャンパス
- Year and Date
  2015-08-31
- Data Source
  KAKENHI-PUBLICLY-26116508
[Presentation] 19SプロテアソームはCut8依存的にセントロメアに結合しCENP-Aの取り込みを限定する2012
- Author(s)
  北川哲平、石井浩二郎、田岡万悟、礒辺俊明、松本智裕
- Organizer
  第31回染色体ワークショップ
- Place of Presentation
  淡路夢舞台国際会議場にて
- Data Source
  KAKENHI-PROJECT-24651047
[Presentation] TSC-Rhebシグナル伝達経路はユビキチンリガーゼPub1とアレスチン様タンパク質Any1の機能を介してアミノ酸トランスポーターの局在を制御している2012
- Author(s)
  中瀬由起子、中瀬舞、村井朋香、大坪瑶子、山本正幸、竹川薫、松本智裕
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2012-12-01
- Data Source
  KAKENHI-PROJECT-19657039
[Presentation] 「19SプロテアソームはCut8依存的にセントロメアに結合しCENP-Aの取り込みを限定する」2012
- Author(s)
  北川哲平、石井浩二郎、田岡万悟、礒辺俊明、松本智裕
- Organizer
  第31回染色体ワークショップ
- Place of Presentation
  淡路夢舞台国際会議場
- Data Source
  KAKENHI-PROJECT-24651047
[Presentation] 動原体に強制局在させた分裂酵母Mph1キナーゼはスピンドルチェックポイントの恒常的な活性化を引き起こす2011
- Author(s)
  伊藤大一輔、齊藤優、松本智裕
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  北海道大学
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PUBLICLY-22019020
[Presentation] TSC-Rhebシグナル伝達経路はユビキチンリガーゼPub1とアレスチン様タンパク質Any1の機能を介してアミノ酸トランスポーターの局在を制御している2011
- Author(s)
  中瀬由起子、中瀬舞、村井朋香、大坪瑶子、山本正幸、竹川薫、松本智裕
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  横浜(招待講演)
- Year and Date
  2011-12-01
- Data Source
  KAKENHI-PROJECT-19657039
[Presentation] TSC-Rhb-TORシグナル伝達経路におけるアミノ酸透過酵素の制御機構2010
- Author(s)
  中瀬由起子、村井朋香、中瀬舞、竹川薫、松本智裕
- Organizer
  酵母遺伝学フォーラム
- Place of Presentation
  奈良
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-19657039
[Presentation] TSC-Rheb-Tor経路とエンドサイトーシス経路との関わり2009
- Author(s)
  中瀬由起子、村井朋香、松本智裕
- Organizer
  弟9回日本分子生物学会
- Place of Presentation
  宮崎
- Year and Date
  2009-05-11
- Data Source
  KAKENHI-PROJECT-19657039
[Presentation] p31cometによるp53の質的制御2008
- Author(s)
  土生敏行、松本智裕
- Organizer
  第25回染色体ワークショップ
- Place of Presentation
  熱海
- Year and Date
  2008-01-30
- Data Source
  KAKENHI-PROJECT-17013044
[Presentation] p31cometの細胞周期における機能2007
- Author(s)
  土生敏行、松本智裕
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-17013044
[Presentation] 紡錘糸チェックポイントの分子機構と癌抑制機構2007
- Author(s)
  松本智裕
- Organizer
  日本環境変異原学会公開シンポジウム2007
- Place of Presentation
  東京
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-17013044
[Presentation] Involvement of S. pombe Aurora kinase in the regulation of heterochromatic imprint at the subtelomere.
- Author(s)
  Masahiro Takado, Tatsuki Kunoh, Yuji Chikashige, Tomohiro Matsumoto
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26550027

1. HABU Toshiyuki (70346071)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
2. NAKASE Yukiko (80402923)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. YANAGIDA Mitsuhiro (80025428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. TAKEDA Shunichi (60188191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TAKEYASU Kunio (40135695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. ISHIKAWA Fuyuki (30184493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 西田栄介 (60143369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ISHII Kojiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 石井俊輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Matsumoto Tomohiro 松本 智裕

MATSUMOTO Tomohiro 松本 智裕

Research Projects

Research Products

Co-Researchers

Analysis of the mechanism of centtome disassemblyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

核膜アンカーに依存したセントロメアクロマチン制御機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Impact and response to DNA damage in mitosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of Cenp-A and HJURP at damage sitesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

スピンドルチェックポイントの解除機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of genome stability undernutritionalstarvation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ゲノム安定性を維持するスピンドルチェックポイントの分子機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

有糸分裂期の放射線応答Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The signal cascade of the spindle checkpointPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Maintenance and Inheritance of Diverse Life by Chromosome Dynamics

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Book] Molecular mechanisms and function of the spindle checkpoint, a puardian of the chromosome stability, in Polyploidization and Cancer2008

Author(s)

Total Pages

Publisher

Data Source

[Book] The dream of every chromosome; equal segregation for a healthy life of the host. Genome Instability and Cancer Development, Chapter3.32006

Author(s)

Total Pages

Publisher

Description

Data Source

[Book] The dream of every chromosome ; equal segregation for a healthy life of the host2005

Author(s)

Publisher

Data Source

[Book] The dream of every chromosome ; equal segregation for a healthy life of the host. Genome Instability and Cancer Development, in Advances in Experimental Medicine and Biology2005

Matsumoto Tomohiro 松本智裕

MATSUMOTO Tomohiro 松本智裕