OZAKI Iwata 尾崎岩太

… Alternative Names

尾崎岩太オザキイワタ

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Researcher Number	80214120
Other IDs
Affiliation (based on the past Project Information) *help	2013: 佐賀大学, 学内共同利用施設等, 准教授 2012: 佐賀大学, 保健管理センター, 准教授 2004 – 2006: 佐賀大学, 保健管理センター, 助教授 1992: 佐賀医科大学, 医学部, 助手
Review Section/Research Field	Except Principal Investigator Gastroenterology / Public health/Health science / Gastroenterology
Keywords	Except Principal Investigator 5-FU / Vitamin K2 / Interferon treatment / Follow-up survey / Screening for liver disease / Prevention for liver cancer / HCV carriers / インターフェロン治療 / 追跡調査 / 肝疾患検診 … More / 肝癌発症予防 / C型肝炎 / matrix metalloproteinase / cyclin D1 / hepatoma cells / vitamin K2 / CDK inhibitor / 転写因子NF-kB / 増殖抑制効果 / Cvclin D1 / 細胞外マトリックス分解酵素 / Cyclin D1 / 肝癌細胞 / Liverdysfunction / Liver fibrosis / Liver regeneration / Laminin / 肝線維化 / 細胞外マトリックス / 線維肝 / 肝障害 / 肝再生 / ラミニン / Hepatocellular carcinoma / Sorafenib Less

肝癌の分子標的治療におけるＶｉｔａｍｉｎ　Ｋ２アジュバント効果の基礎的研究
- Principal Investigator
  
  MIZUTA Toshihiko
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Saga University
Follow-up survey of about 11,000 individuals with positive for anti-HCV identified in Saga screening system and its preventive effect for occurrence of hepatocellular carcinoma
- Principal Investigator
  
  YASUTAKE Tsutomu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Public health/Health science
- Research Institution
  Saga University
Analysis on the mechanism of growth inhibition by vitamin K2 in hepatoma cells
- Principal Investigator
  
  MIZUTA Toshihiko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Saga University
Sigmficance of novel laminin in liver regeneration, acute injury and chronic fibrosis.
- Principal Investigator
  
  SAKAI Takahiro
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  SAGA MEDICAL SCHOOL

All 2014 2013 2012 2007

All Journal Article Presentation

[Journal Article] Control of a tumor suppressor PDCD4: Degradation mechanisms of the protein in hepatocellular carcinoma cells2014
- Author(s)
  Matsuhashi S, Hamajima H, Xia JH, Zhang H, Mizuta T, Anzai K, Ozaki I
- Journal Title
  
  Cell Signal
  
  Volume: 26 Issue: 3 Pages: 603-610
- DOI
  10.1016/j.cellsig.2013.11.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590982
[Journal Article] The role of PKC isoforms in the inhibition of NF-κB activation by vitamin K2 in human hepatocellular carcinoma cells.2012
- Author(s)
  Xia J, Matsuhashi S, Hamajima H, Iwane S, Takahashi H, Eguchi Y, Mizuta T, Fujimoto K, Kuroda S, Ozaki I.
- Journal Title
  
  J Nutr Biochem
  
  Volume: 23 Issue: 12 Pages: 1668-1675
- DOI
  10.1016/j.jnutbio.2011.11.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590982
[Journal Article] Menatetrenone, a vitamin K2 analogue, inhibits hepatocellular carcinoma cells by suppressing cyclin D1 expression through the NF-kB activation inhibition.2007
- Author(s)
  Ozaki I
- Journal Title
  
  Clin Cancer Res 13
  
  Pages: 2236-2245
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390188
[Journal Article] Menatetrenone, a vitamin K2 analogue, inhibits hepatocellular carcinoma cells by suppressing cyclin D1 expression through the NF-kB activation inhibition.2007
- Author(s)
  Ozaki I
- Journal Title
  
  Clin Cancer Res (in press)
- Data Source
  KAKENHI-PROJECT-17390188
[Presentation] Factors associated with long-term administration of sorafenib in patients with advanced hepatocellular carcinoma2014
- Author(s)
  Chika Tsuji, Saori Kamachi, Shunya Nakashita, Yasushi Ide, Taiga Otsuka, Iwata Ozaki, Toshihiko Mizuta
- Organizer
  APASL Liver Week 2014
- Place of Presentation
  Brisbane
- Data Source
  KAKENHI-PROJECT-24590982
[Presentation] Mitogen- and phosphorylation site-specific degradation mechanisms of tumor suppressor PDCD4 in human HCC cells2013
- Author(s)
  Iwata Ozaki, Hiroshi Hamajima, Jinghe Xia, Jingyan Qi, Toshihiko Mizuta, Keizo Anzai, Sachiko Matsuhashi
- Organizer
  AASLD 64rd The Liver Meeting 2013
- Place of Presentation
  Washington DC
- Data Source
  KAKENHI-PROJECT-24590982
[Presentation] Protein kinase C(PKC)による低酸素誘導HIF-1誘導増強効果とVitamin K２による調節2013
- Author(s)
  Jinghe Xia、尾崎岩太、Jingyan Qi、桑代卓也、岩根紳治、井手康史、江口有一郎、水田敏彦、安西慶三、松橋幸子
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590982
[Presentation] 進行肝細胞癌に対するソラフェニブ治療におけるビタミンK２併用の効果2013
- Author(s)
  中下俊哉、小平俊一、蒲池紗央里、岩根紳治、井手康史、大塚大河、江口有一郎、川添聖治、尾崎岩太、水田敏彦
- Organizer
  第49回日本肝癌研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590982
[Presentation] 進行肝細胞癌に対する化学療法におけるビタミンK2のアジュバント効果2013
- Author(s)
  中下俊哉、蒲池紗央里、小平俊一、岩根紳治、井手康史、大塚大河、江口有一郎、川添聖治、安西慶三、尾崎岩太、水田敏彦
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590982
[Presentation] Adjuvant effect of administration of vitamin K2 combined with sorafenib in subjects with advanced hepatocellular carcinoma2013
- Author(s)
  Shunya Nakashita, Taiga Otsuka, Chika Tsuji, Saori Kamachi, Yasushi Ide, Seiji Kawazoe, Yuichiro Eguchi, Iwata Ozaki, Toshihiko Mizuta
- Organizer
  ILCA 2013
- Place of Presentation
  Washington DC
- Data Source
  KAKENHI-PROJECT-24590982
[Presentation] 進行肝細胞癌に対するソラフェニブ＋ビタミンK2併用療法2013
- Author(s)
  中下俊哉、小平俊一、蒲池紗央里、岩根紳治、井手康史、大塚大河、江口有一郎、川添聖治、尾崎岩太、水田敏彦
- Organizer
  第7回日本肝がん分子標的治療研究会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-24590982
[Presentation] Vitamin K2 inhibits HIF-1α activity by suppressing PKC-δ in normoxic but not hypoxic level in hepatocellular carcinoma cells.2012
- Author(s)
  Xia JingHe、尾崎岩太、松橋幸子、斉ジンヤン、岩根紳治、高橋宏和、江口有一郎、水田敏彦、安西慶三
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590982
[Presentation] 肝細胞癌でのNF-κB活性化におけるprotein kinase C isoformの役割2012
- Author(s)
  尾崎岩太、夏京合、松橋幸子、斉女青言、岩根紳治、高橋宏和、江口有一郎、水田敏彦
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-24590982
[Presentation] 高齢者肝癌に対するsorafenib療法の安全性および有用性2012
- Author(s)
  中下俊哉、岡田倫明、磯田広史、岩根紳治、高橋宏和、大塚大河、江口有一郎、川添聖治、尾崎岩太、水田敏彦
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590982
[Presentation] 肝細胞癌に対するソラフェニブ療法とリザーバー動注療法（New FP療法）に関する比較検討2012
- Author(s)
  中下俊哉、岡田倫明、磯田広史、高橋宏和、岩根紳治、大塚大河、江口有一郎、川添聖治、尾崎岩太、水田敏彦
- Organizer
  第54回日本消化器病学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24590982
[Presentation] Sorafenib versus hepatic arterial infusion chemotherapy for treatment of advanced hepatocellular carcinoma: a comparison of efficacy.2012
- Author(s)
  Shunya Nakashita, Taiga Otsuka, Seiji Kawazoe, Yuichiro Eguchi, Saori Kamachi, Hiroshi Isoda, Takumi Akiyama, Hirokazu Takahashi, Shinji Iwane, Masaru Fujimoto, Iwata Ozaki, Toshihiko Mizuta
- Organizer
  6th ILCA Annual Conference
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-24590982

1. MIZUTA Toshihiko (80253607)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
2. SAKAI Takahiro (30010367)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. YASUTAKE Tsutomu (20336126)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. EGUCHI Yuichiro (80343341)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OZAKI Iwata 尾崎 岩太

尾崎 岩太 オザキ イワタ

Research Projects

Research Products

Co-Researchers

肝癌の分子標的治療におけるＶｉｔａｍｉｎ Ｋ２アジュバント効果の基礎的研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Follow-up survey of about 11,000 individuals with positive for anti-HCV identified in Saga screening system and its preventive effect for occurrence of hepatocellular carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis on the mechanism of growth inhibition by vitamin K2 in hepatoma cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Sigmficance of novel laminin in liver regeneration, acute injury and chronic fibrosis.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Control of a tumor suppressor PDCD4: Degradation mechanisms of the protein in hepatocellular carcinoma cells2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The role of PKC isoforms in the inhibition of NF-κB activation by vitamin K2 in human hepatocellular carcinoma cells.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Menatetrenone, a vitamin K2 analogue, inhibits hepatocellular carcinoma cells by suppressing cyclin D1 expression through the NF-kB activation inhibition.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Menatetrenone, a vitamin K2 analogue, inhibits hepatocellular carcinoma cells by suppressing cyclin D1 expression through the NF-kB activation inhibition.2007

Author(s)

Journal Title

Data Source

[Presentation] Factors associated with long-term administration of sorafenib in patients with advanced hepatocellular carcinoma2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Mitogen- and phosphorylation site-specific degradation mechanisms of tumor suppressor PDCD4 in human HCC cells2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Protein kinase C(PKC)による低酸素誘導HIF-1誘導増強効果とVitamin K２による調節2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 進行肝細胞癌に対するソラフェニブ治療におけるビタミンK２併用の効果2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 進行肝細胞癌に対する化学療法におけるビタミンK2のアジュバント効果2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Adjuvant effect of administration of vitamin K2 combined with sorafenib in subjects with advanced hepatocellular carcinoma2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 進行肝細胞癌に対するソラフェニブ＋ビタミンK2併用療法2013

Author(s)

OZAKI Iwata 尾崎岩太

尾崎岩太オザキイワタ

肝癌の分子標的治療におけるＶｉｔａｍｉｎ　Ｋ２アジュバント効果の基礎的研究