OYAMA Yasuo 小山保夫

Researcher Number	80214229
Other IDs
Affiliation (based on the past Project Information) *help	2017 – 2018: 徳島大学, 大学院社会産業理工学研究部(生物資源産業学域), 教授 2016: 徳島大学, 大学院生物資源産業学研究部, 教授 2011 – 2015: 徳島大学, 大学院ソシオ・アーツ・アンド・サイエンス研究部, 教授 2000 – 2002: 徳島大学, 総合科学部, 教授 1996: Faculty of Integrated Arts and Sciences, The University of Tokushima, Professor, 総合科学部, 教授 … More 1994 – 1995: 徳島大学, 総合科学部, 助教授 1991 – 1992: 徳島大学, 総合科学部, 助教授 1989 – 1990: Tohoku University School of Medicine, Assistant Researcher, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator General pharmacology / 環境影響評価(含放射線生物学) / Risk sciences of radiation and chemicals / Risk sciences of radiation/Chemicals Except Principal Investigator Neurophysiology and muscle physiology / 環境影響評価(含放射線生物学) / 応用薬理学・医療系薬学
Keywords	Principal Investigator 細胞毒性 / 神経毒性 / NMDA / 有機錫 / 環境影響評価 / カルシウム / 亜鉛 / 亜鉛イオン / フローサイトメーター / 蛍光プローブ … More / immunotoxicity / neurotoxicity / cytotoxicity / environmental pollution / apoptosis / organotin / tri-n-butyltin / トリフェニル錫 / アポトーシス / 細胞死 / 胸腺細胞 / 脳神経細胞 / トリプチル錫 / 免疫毒性 / 環境汚染 / トリブチル錫 / Ionic channels / Brain neuron / Ca permeability / Cytosol calcium / Tributyltin / Triphenyltin / Triorganotin / Neurotoxicity / 細胞内カルシウム / 光化学測定法 / ナトリウム電流 / 電圧固定法 / 単離細胞 / 中枢神経細胞 / 細胞内器官 / 小脳顆粒細胞 / イオン・チャネル / 有機スズ化合物 / 細胞内カルシウムイオン / 抗菌剤 / 防汚剤 / 酸化ストレス / 国際情報交換 / レーザー共焦点顕微鏡 / ethidium / fluo-3 / 膜イオン透過性 / amyloid β-protein … More Except Principal Investigator NMDA / ラット / T-type Ca channel / strychnine / Cl^- response / glycine / isolated neuron / hypothalamus / rat / ストリキニーネ / 交叉脱感作 / 用量反応曲線 / Cl応答 / 単離ニューロン / N-メチル-D-アスパラギン酸 / 脊随後角 / 孤束核 / 視床下部腹内側角 / T型Caチャネル / ストリキニ-ネ / Cl^-応答 / グリシン / 単離ニュ-ロン / 視床下部腹内側核 / Cell viability / Intracellular Ca / Organometal / 蛍光化学 / 細胞内カルシウムイオン / レーザー共焦点顕微鏡 / フローサイトメーター / ethidium / fluo-3 / 蛍光プローブ / 膜イオン透過性 / 神経毒性 / 細胞毒性 / 細胞内カルシウム / 有機金属化合物 / Quinolone / Non-steroidal anti-inflammatory / gamma-Aminobutyric acid-A response / Rat hippocampal neuron / 4ービフェニル酢酸(BPA) / 痙攣誘発作用 / 非ステロイド系抗炎症剤 / 新キノロン剤 / 脳虚血 / 周令差 / 受容器間の修飾 / N-メチルーD-アスパラギン酸 / アセチルコリン / 単離中枢神経細胞 / パッチクランプ法 Less

Effects of zinc ion on the cytotoxicity of chemicalsPrincipal Investigator
- Principal Investigator
  
  OYAMA Yasuo
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  The University of Tokushima
toxicolgical role of Zn2+ in cell death induced by chemical stressPrincipal Investigator
- Principal Investigator
  
  OYAMA Yasuo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  The University of Tokushima
Analysis on various toxic actions of organotins including tri-n-butyltinPrincipal Investigator
- Principal Investigator
  
  OYAMA Yasuo
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  The University of Tokushima
Amyloid β-protein fragmentによる細胞膜の透過性の解析Principal Investigator
- Principal Investigator
  
  小山保夫
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  The University of Tokushima
Cytometric analysis on roganometal-induced increase in intracellular Ca
- Principal Investigator
  
  TOMIYOSHI Fukiyo
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  The University of Tokushima
Evaluation on neurotoxicity using dissociated mammalian CNS neuronsPrincipal Investigator
- Principal Investigator
  
  OYAMA Yasuo
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  The University of Tokushima
Interaction of various-non-steroidal anti-inflammatories and quinolone antimicrobials on GABA response in rat dissociated hippocampal pyramidal neurons
- Principal Investigator
  
  NAKAYE Toshio
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tohoku University
細胞内遊離CaイオンによるGABA受容器・CCチャネル複合体の制御機構
- Principal Investigator
  
  AKAIKE Norio
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
Macro- and microscopic analysis of glycine-gated response in isolated CNS neurons.
- Principal Investigator
  
  AKAIKE Norio
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  TOHOKU UNIVERSITY
  Kyushu University

All 2019 2018 2017 2016 2015 2014 2013 2012 2011

All Journal Article

[Journal Article] Modification of cell vulnerability to oxidative stress by N-(3-oxododecanoyl)-L-homoserine-lactone, a quorum sensing molecule, in rat thymocytes2019
- Author(s)
  Yumiko Nishimura-Danjobara, Keisuke Oyama, Tomohiro Oyama, Kumio Yokoigawa, Yasuo Oyama
- Journal Title
  
  Chemico-Biological Interactions
  
  Volume: 302 Pages: 143-148
- DOI
  10.1016/j.cbi.2019.02.006
- NAID
  120006797337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26340039, KAKENHI-PROJECT-18K02204
[Journal Article] Membrane hyperpolarization and depolarization of rat thymocytes by azoxystrobin, a post harvest fungicide2019
- Author(s)
  Naohiro Imura, Masamichi Ae, Rin Hoshino, Masami Abe, Tatsuya Yamamuro, Keisuke Oyama, Yasuo Oyama
- Journal Title
  
  Chemico-Biological Interactions
  
  Volume: 300 Pages: 35-39
- DOI
  10.1016/j.cbi.2019.01.006
- NAID
  120006776194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Captan-induced increase in the concentrations of intracellular Ca2+ and Zn2+ and its correlation with oxidative stress in rat thymic lymphocytes2018
- Author(s)
  Tomomi Inoue, Maika Kinoshita, Keisuke Oyama, Norio Kamemura, Yasuo Oyama
- Journal Title
  
  Environmental Toxicology and Pharmacology
  
  Volume: 63 Pages: 78-83
- DOI
  10.1016/j.etap.2018.08.017
- NAID
  120006714025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Conflicting actions of 4-vinylcatechol in rat lymphocytes under oxidative stress induced by hydrogen peroxid2018
- Author(s)
  Takumi Kishida, Yurie Funakoshi, Yuya Fukuyama, Sari Honda, Toshiya Masuda & Yasuo Oyama
- Journal Title
  
  Drug and Chemical Toxicology
  
  Volume: － Issue: 4 Pages: 1-6
- DOI
  10.1080/01480545.2018.1492604
- NAID
  120006706954
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02892, KAKENHI-PROJECT-26340039
[Journal Article] Zinc-dependent and independent actions of hydroxyhydroquinone on rat thymic lymphocytes2018
- Author(s)
  Honoka Wada, Keisuke Oyama, Risa Kamae, Toshiya Masuda, Kaori Kanemaru, Kumio Yokoigawa and Yasuo Oyama
- Journal Title
  
  Drug and Chemical Toxicology
  
  Volume: 9 Issue: 5 Pages: 1-6
- DOI
  10.1080/01480545.2018.1429462
- NAID
  120006560582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K02204, KAKENHI-PROJECT-15H02892, KAKENHI-PROJECT-26340039
[Journal Article] Hyperpolarization by N-(3-oxododecanoyl)-L-homoserine-lactone, a quorum sensing molecule, in rat thymic lymphocytes2018
- Author(s)
  Yumiko Nishimura-Danjobara, Keisuke Oyama, Kumio Yokoigawa and Yasuo Oyama
- Journal Title
  
  Chemico-Biological Interactions
  
  Volume: 283 Pages: 91-96
- DOI
  10.1016/j.cbi.2018.02.008
- NAID
  120006556226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K02204, KAKENHI-PROJECT-26340039
[Journal Article] Cellular adverse actions of dibromoacetonitrile, a water bacterial control, at sublethal levels in rat thymocytes2018
- Author(s)
  Takumi Kishida, Kenji Akiyoshi, Erdenedalai Erdenebat, Enhetomuru Anu, Shoji Imai, Yasuo Oyama
- Journal Title
  
  Toxicology In Vitro
  
  Volume: 51 Pages: 145-149
- DOI
  10.1016/j.tiv.2018.05.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Cytometrical analysis of the adverse effects of indican, indoxyl, indigo, and indirubin on rat thymic lymphocytes2018
- Author(s)
  Yurie Funakoshi, Ayako Azuma, Mizuki Ishikawa, Satoru Itsuki, Yasuaki Tamura, Kaori Kanemaru, Shogo Hirai and Yasuo Oyama
- Journal Title
  
  Toxicology Research
  
  Volume: 7 Issue: 3 Pages: 513-520
- DOI
  10.1039/c7tx00244k
- NAID
  120006592857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Some adverse actions of chlorothalonil at sublethal levels in rat thymic lymphocytes: Its relation to Zn2+2018
- Author(s)
  Mizuki Ikeda, Junji Deguchi, Shota Fukushima, Ai Qingyu, Norihiro Katayama, Hajime Miura, Yasuo Oyama
- Journal Title
  
  Environmental Toxicology and Pharmacology
  
  Volume: 59 Pages: 61-65
- DOI
  10.1016/j.etap.2018.03.006
- NAID
  120006592856
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26340039, KAKENHI-PROJECT-15K01276
[Journal Article] Ziram, a dithiocarbamate fungicide, exhibits pseudo-cytoprotective actions against oxidative stress in rat thymocytes: Possible environmental risks.2018
- Author(s)
  Kanemoto-Kataoka Y, Oyama K, Oyama TM, Ishibashi H, Oyama Y
- Journal Title
  
  Environmental Research
  
  Volume: 160 Pages: 232-238
- DOI
  10.1016/j.envres.2017.09.027
- NAID
  120006732206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K13050, KAKENHI-PROJECT-26340039, KAKENHI-PROJECT-15H03046
[Journal Article] N-(3-oxododecanoyl)-L-homoserine-lactone, a quorum sensing molecule, affects cellular content of nonprotein thiol content in rat lymphocytes: Its relation with intracellular Zn2+2018
- Author(s)
  Yumiko Nishimura-Danjobara, Keisuke Oyama, Kaori Kanemaru, Keiko Takahashi, Kumio Yokoigawa and Yasuo Oyama
- Journal Title
  
  Chemico-Biological Interactions
  
  Volume: 280 Pages: 28-32
- DOI
  10.1016/j.cbi.2017.12.013
- NAID
  120006542676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K02204, KAKENHI-PROJECT-26340039
[Journal Article] Cetylpyridinium chloride at sublethal levels increases the susceptibility of rat thymic lymphocytes to oxidative stress2017
- Author(s)
  Hiroto Imai, Fumiya Kita, Sho Ikesugi, Masami Abe, Shizuka Sogabe, Yumiko Nishimura-Danjobara, Hajime Miura and Yasuo Oyama
- Journal Title
  
  Chemosphere
  
  Volume: 170 Pages: 118-123
- DOI
  10.1016/j.chemosphere.2016.12.023
- NAID
  120006542675
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Zinc-related actions of sublethal levels of benzalkonium chloride: Potentiation of benzalkonium cytotoxicity by zinc2017
- Author(s)
  Tsuyoshi Mitani, Ahmed Elhossany Elmarhomy Ibrahim, Luvsandorj Dulamjav, Enkhtumur Anu, Shohei Saitoh, Shiro Ishida and Yasuo Oyama
- Journal Title
  
  Chemico-Biological Interactions
  
  Volume: 268 Pages: 31-36
- DOI
  10.1016/j.cbi.2017.02.017
- NAID
  120006404392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Hydroxyhydroquinone, a by-product of coffee bean roasting, increases intracellular Ca2+ concentration in rat thymic lymphocytes2017
- Author(s)
  Risa Kamae, Shoko Nojima, Kenji Akiyoshi, Shoki Setsu, Sari Honda, Toshiya Masuda and Yasuo Oyama
- Journal Title
  
  Food and Chemical Toxicology
  
  Volume: 102 Pages: 39-45
- DOI
  10.1016/j.fct.2017.01.025
- NAID
  120006382862
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26340039, KAKENHI-PROJECT-15H02892, KAKENHI-PROJECT-16J03454
[Journal Article] Zinc is a determinant of the cytotoxicity of Ziram, a dithiocarbamate fungicide, in rat thymic lymphocytes: Possible environmental risk2017
- Author(s)
  Yumiko Kanemoto-Kataoka, Tomohiro Oyama, Hitoshi Ishibashi and Yasuo Oyama
- Journal Title
  
  Toxicology Research
  
  Volume: 6 Issue: 4 Pages: 499-504
- DOI
  10.1039/c7tx00052a
- NAID
  120006490502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Change in plasma membrane potential of rat thymocytes by tert-butylhydroquinone, a food additive: Possible risk on lymphocytes2017
- Author(s)
  Maki Takeda, Keisuke Oyama, Norio Kamemura, Kaori Kanemaru, Keizo Yuasa, Kumio Yokoigawa and Yasuo Oyama
- Journal Title
  
  Food and Chemical Toxicology
  
  Volume: 109 Pages: 296-301
- DOI
  10.1016/j.fct.2017.09.017
- NAID
  120006510951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26340039, KAKENHI-PROJECT-15K00784
[Journal Article] Cytometric analysis on cytotoxicity of 4,4′-methylenediphenyl diisocyanate, a chemical allergen, in rat thymocytes2017
- Author(s)
  Keisuke Oyama, Norikazu Miyoshi and Yasuo Oyama
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 4 Issue: 4 Pages: 173-178
- DOI
  10.2131/fts.4.173
- NAID
  130005791103
- ISSN
  2189-115X
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Diverse cellular actions of tert-butylhydroquinone, a food additive, on rat thymocyte2017
- Author(s)
  Norio Kamemura, Keisuke Oyama, Kaori Kanemaru, Kumio Yokoigawa and Yasuo Oyama
- Journal Title
  
  Toxicology Research
  
  Volume: 6 Issue: 6 Pages: 922-929
- DOI
  10.1039/c7tx00183e
- NAID
  120006524488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26340039, KAKENHI-PROJECT-15K00784
[Journal Article] Cytotoxic actions of 2, 2-dibromo-3-nitrilopropionamide, a biocide in hydraulic fracturing fluids, on rat thymocytes2016
- Author(s)
  Mizuki Ishikawa, Ryosuke Muraguchi, Ayako Azuma, Shogo Nawata, Tetsuya Katsuur, Mutsumi Miya, Tohru Naito and Yasuo Oyama
- Journal Title
  
  Toxicology Research
  
  Volume: 5 Issue: 5 Pages: 1329-1334
- DOI
  10.1039/c6tx00027d
- NAID
  120006324297
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Chlorhexidine possesses unique cytotoxic actions in rat thymic lymphocytes: Its relation with electrochemical property of membranes2016
- Author(s)
  Kayo Nonami, Shohei Saitoh, Yumiko Nishimura-Danjobara, Shiro Ishida and Yasuo Oyama
- Journal Title
  
  Environmental Toxicology and Pharmacology
  
  Volume: 48 Pages: 17-21
- DOI
  10.1016/j.etap.2016.09.024
- NAID
  120006365853
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Zinc increases vulnerability of rat thymic lymphocytes to arachidonic acid under in vitro conditions.2016
- Author(s)
  Eiko Niwa, Tsuyoshi Mitani, Shohei Saitoh, Kaori Kanemaru, Shiro Ishida, Kumio Yokoigawa and Yasuo Oyama
- Journal Title
  
  Food and Chemical Toxicology
  
  Volume: 96 Pages: 177-182
- DOI
  10.1016/j.fct.2016.08.008
- NAID
  120006334175
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Cytotoxic actions of N-(2,4,6-trichlorophenyl)maleimide (IT-354), an antifouling agent, in rat thymic lymphocytes2015
- Author(s)
  Eri Fukunaga, Shohei Saitoh, Yuya Kurumi, Yurie Ohiwa, Eri Kurozumi and Yasuo Oyama
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 2 Pages: 217-222
- NAID
  130005111716
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Cell death process induced by hydrogen peroxide is accelerated by clioquinol in rat thymocytes2015
- Author(s)
  Tomohiro Oyama, Eri Fukunaga and Yasuo Oyama
- Journal Title
  
  Natural Science Research
  
  Volume: 29 Pages: 31-33
- NAID
  110010016078
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Zn<sup>2+</sup>-dependent increase in cells with phosphatidylserine-exposed membranes after treatment with submicromolar concentrations of 2-<i>n</i>-octyl-4-isothiazolin-3-one in rat thymocytes2015
- Author(s)
  Eri Fukunaga, Sari Honda, Yuji Hashimoto, Yasuaki Tamaru, Shiro Ishida and Yasuo Oyama
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 2 Issue: 5 Pages: 209-216
- DOI
  10.2131/fts.2.209
- NAID
  130005109680
- ISSN
  2189-115X
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Zn2+-dependence of the synergistic increase in rat thymocyte cell lethality caused by simultaneous application of 4,5-dichloro-2-octyl-4-isothiazolin-3-one (DCOIT) and H2O22015
- Author(s)
  Shohei Saitoh, Eri Fukunaga, Hana Ohtani and Yasuo Oyama
- Journal Title
  
  Chemosphere
  
  Volume: 135 Pages: 447-452
- DOI
  10.1016/j.chemosphere.2014.10.089
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Increase in intracellular Ca2+ level by phenylsulfamide fungicides, tolylfluanid and dichlofluanid, in rat thymic lymphocytes2015
- Author(s)
  Eri Fukunaga, Kana Enma, Shohei Saitoh, Yumiko Nishimura-Danjyobara, Yasuo Oyama and Norio Akaike
- Journal Title
  
  Environmental Toxicology and Pharmacology
  
  Volume: 40 Issue: 1 Pages: 149-155
- DOI
  10.1016/j.etap.2015.06.004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Effects of N,N-dimethyldodecylamine-N-oxide on some cellular parameters of rat thymocytes2015
- Author(s)
  Eri Fukunaga, Yurie Ohiwa, Mari Yamada, Ayaka Sumi, Masaya Satoh and Yasuo Oyama
- Journal Title
  
  Natural Science Research
  
  Volume: 29 Pages: 1-4
- NAID
  110010016063
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Modulation of excitatory synaptic transmission in rat hippocampal CA3 neurons by triphenyltin, an environmental pollutant2015
- Author(s)
  Masahito Wakita, Yasuo Oyama, Yuko Takase and Norio Akaike
- Journal Title
  
  Chemosphere
  
  Volume: 120 Pages: 598-607
- DOI
  10.1016/j.chemosphere.2014.09.073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Dithiocarbamate fungicides increase intracellular Zn2+ levels by increasing influx of Zn2+ in rat thymic lymphocytes2015
- Author(s)
  Yumiko Kanemoto-Kataoka, Tomohiro Oyama, Hitoshi Ishibashi and Yasuo Oyama
- Journal Title
  
  Chemico-Biological Interactions
  
  Volume: 237 Pages: 80-86
- DOI
  10.1016/j.cbi.2015.05.014
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Elevation of the intracellular Zn2+ level by 2-n-octyl-4-isothiazolin-3-one in rat thymocytes: an involvement of a temperature-sensitive Zn2+ pathway2015
- Author(s)
  Eri Fukunaga, Tomohiro M. Oyama, Yasuo Oyama
- Journal Title
  
  Toxicology Research
  
  Volume: 4 Issue: 1 Pages: 65-70
- DOI
  10.1039/c4tx00060a
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Clioquinol, a lipophilic Zn2+ chelator, augments and attenuates the cytotoxicity of H2O2: A bell-shaped response curve of the effects of the drug,2014
- Author(s)
  Tomohiro Oyama, Keisuke Oyama, Eri Fukunaga, Hitoshi Ishibashi and Yasuo Oyama
- Journal Title
  
  Toxicology Research
  
  Volume: 3 Issue: 2 Pages: 110-117
- DOI
  10.1039/c3tx50097g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078, KAKENHI-PROJECT-24590739, KAKENHI-PROJECT-26340039
[Journal Article] Effects of tetracaine and lidocaine on intracellular Zn^<2+> levels in rat neurons : Preliminary analysis with FluoZin-3 fluorescence2014
- Author(s)
  Eri Fukunaga, Yasuo Oyama
- Journal Title
  
  Natural Science Research
  
  Volume: Vol. 28, No. 1 Pages: 1-5
- NAID
  110009915546
- URL
  http://web.ias.tokushima-u.ac.jp/bulletin/nat/nat28-1-1.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Changes in cellular thiol content and intracellular Zn2+ level by 1, 4-naphthoquinone in rat thymocytes2014
- Author(s)
  Eri Fukunaga, Shiro Ishida, Yasuo Oyama
- Journal Title
  
  Chemico-Biological Interactions
  
  Volume: 222 Pages: 1-6
- DOI
  10.1016/j.cbi.2014.08.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] The paradoxical effect of 1,4-naphthoquinone on the process of cell death induced by hydrogen peroxide in rat thymocytes2014
- Author(s)
  Hana Ohtani, Eri Fukunaga, Yasuo Oyama, Shiro Ishida, Norio Akaike
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 1 Pages: 123-129
- NAID
  130005083349
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26340039
[Journal Article] Triclocarban-induced change in intracellular Ca2+ level in rat thymocytes: Cytometric analysis with Fluo-3 under Zn2+-free conditions.2014
- Author(s)
  Yukari Miura, Xiaohui Chen, Saki Yamada, Aya Sugihara, Molomjamts Enkhjargal, Yuanzhi Sun, Keiko Kuroda, Masaya Satoh and Yasuo Oyama
- Journal Title
  
  Environmental Toxicology and Pharmacology
  
  Volume: 37 Issue: 2 Pages: 563-570
- DOI
  10.1016/j.etap.2014.01.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Nanomolar concentration of triclocarban increases the vulnerability of rat thymocytes to oxidative stress2013
- Author(s)
  Yasuhiro Kanbara, Kazuhiro Murakane, Yumiko Nishimura, Masaya Satoh, Yasuo Oyama
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: Vol. 38, No. 1 Pages: 49-55
- NAID
  10031138726
- URL
  https://www.jstage.jst.go.jp/article/jts/38/1/38.../_pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Effect of triclocarban on membrane potential of rat thymocytes: Assessment with bis-(1,3-dibutylbarbituric acid)trimethine oxonol2013
- Author(s)
  Yuanzhi Sun, Molomjamts Enkhjargal, Aya Sugihara, Saki Yamada, Xiaohui Chen, Yukari Miura, Eri Fukunaga, Masaya Satoh and Yasuo Oyama
- Journal Title
  
  Natural Science Research
  
  Volume: 27 Pages: 51-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Synergistic increase in cell lethality by dieldrin and H2O2 in rat thymocytes: Effect of dieldrin on the cells exposed to oxidative stress.2013
- Author(s)
  Tsolmon Chimeddorj, Tomoko Suzuki, Kazuhiro Murakane, Miyuki Inai, Masaya Satoh and Yasuo Oyama
- Journal Title
  
  Chemosphere
  
  Volume: 93 Issue: 2 Pages: 353-358
- DOI
  10.1016/j.chemosphere.2013.04.092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Effect of triclocarban on membrane potential of rat thymocytes : Assessment with bis-(1,3-dibutylbarbituric acid) trimethine oxonol2013
- Author(s)
  Yuanzhi Sun, Molomjamts Enkhjargal, Aya Sugihara, Saki Yamada, Xiaohui Chen, Yukari Miura, Eri Fukunaga, Masaya Satoh, Yasuo Oyama
- Journal Title
  
  Natural Science Research
  
  Volume: Vol. 27, No. 4 Pages: 51-57
- URL
  http://www.lib.tokushima-u.ac.jp/repository/metadata/105960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Nanomolar concentration of triclocarban increases the vulnerability of rat thymocytes to oxidative stress2013
- Author(s)
  Yasuhiro Kanbara, Kazuhiro Murakane, Yumiko Nishimura, Masaya Satoh and Yasuo Oyama
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 38 Issue: 1 Pages: 49-55
- DOI
  10.2131/jts.38.49
- NAID
  10031138726
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Role of Zn2+ in restoration of nonprotein thiol content in the cells under chemical stress induced by triclocarban2013
- Author(s)
  Eri Fukunaga, Yasuhiro Kanbara, Yumi Hirao and Yasuo Oyama
- Journal Title
  
  Natural Science Research
  
  Volume: 27 Pages: 1-5
- NAID
  110009915516
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Role of Zn^<2+> in restoration of nonprotein thiol content in the cells under chemical stress induced by triclocarban2013
- Author(s)
  Eri Fukunaga, Yasuhiro Kanbara, Yumi Hirao, Yasuo Oyama
- Journal Title
  
  Natural Science Research
  
  Volume: Vol. 27, No. 1 Pages: 1-5
- NAID
  110009915516
- URL
  http://www.lib.tokushima-u.ac.jp/repository/metadata/104978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Decrease in intracellular Zn^<2+> level by propranolol : A model experiment using rat thymocytes2012
- Author(s)
  Yasuhiro Kanbara, Hakaru Seo, Yumiko Nishimura, Yasuo Oyama
- Journal Title
  
  Natural Science Research
  
  Volume: Vol. 26, No. 3 Pages: 11-16
- NAID
  110009517155
- URL
  http://www.lib.tokushima-u.ac.jp/repository/file/96890/20120620154747/LID201206201003.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Yttrium decreases the intracellular Zn2+ concentration in rat thymocytes by attenuating a temperature-sensitive Zn2L influx2012
- Author(s)
  Yusuke Takahashi et al.
- Journal Title
  
  Environmental Toxicology and Pharmacology
  
  Volume: 34 Issue: 2 Pages: 574-578
- DOI
  10.1016/j.etap.2012.07.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] A comaprison of the cellular actions of polaprezinc (zinc-L-carnosine) and ZnCl22012
- Author(s)
  Hakaru Seo et al.
- Journal Title
  
  Life Science
  
  Volume: 90 Issue: 25-26 Pages: 1015-1019
- DOI
  10.1016/j.lfs.2012.05.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Further analysis on lidocaine-induced increase in intracellular Zn2+ concentration: Cytometric model study using FlioZin-3, 5-chloromethylfluorescein, and rat thymocytes2012
- Author(s)
  Yumiko Nishimura and Yasuo Oyama
- Journal Title
  
  Natural Science Research
  
  Volume: 26 Pages: 7-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Triclosan, an antibacterial agent, increases intracellular Zn^<2+> concentration in rat thymocytes : Its relation to oxidative stress2012
- Author(s)
  Ikumi Tamura, Yasuhiro Kanbara, Minoru Saito, Kanna Horimono, Masaya Satoh, Hiroshi Yamamoto, Yasuo Oyama
- Journal Title
  
  Chemosphere
  
  Volume: Vol. 86, No. 1 Issue: 1 Pages: 70-75
- DOI
  10.1016/j.chemosphere.2011.09.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Clioquinol-induced increase and decrease in the intracellular Zn2+ level in rat thymocytes2012
- Author(s)
  Tomohiro Oyama et al.
- Journal Title
  
  Life Science
  
  Volume: 91 Issue: 23-24 Pages: 1216-1220
- DOI
  10.1016/j.lfs.2012.09.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Nanomolar concentrations of zinc pyrithione increase cell susceptability to oxidative stress induced by hydrogen peroxide in rat thymocytes2012
- Author(s)
  Tomohiro Oyama et al.
- Journal Title
  
  Chemosphere
  
  Volume: 87 Issue: 11 Pages: 1316-1322
- DOI
  10.1016/j.chemosphere.2012.01.052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Elevation of intarcellular Zn2+ level by nanomolar concentrations of triclocarban in rat thymocytes2012
- Author(s)
  Junpei Morita et al.
- Journal Title
  
  Toxixology Letters
  
  Volume: 215 Issue: 3 Pages: 208-213
- DOI
  10.1016/j.toxlet.2012.10.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Further analysis on lidocaine-induced increase in intracellular Zn^<2+> concentration : Cytometric model study using FluoZin-3, 5-chloromethylfluorescein, and rat thymocytes2012
- Author(s)
  Yumiko Nishimura, Yasuo Oyama
- Journal Title
  
  Natural Science Research
  
  Volume: Vol. 26, No. 2 Pages: 7-10
- NAID
  110009517148
- URL
  http://www.lib.tokushima-u.ac.jp/repository/file/96861/20120517114206/LID201205171003.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] NOR-3, a donor of nitric oxide, increases intracellular Zn^<2+> concentration and decreases cellular thiol content : A model experiment using rat thymocytes, FluoZin-3, and 5-chloromethylfluorescein2011
- Author(s)
  Soya Harada, Chiharu Kubota, Natsuho Kitano, Takuya Kawanai, Kazuki Koizumi, Yasuo Oyama, Akio Kinazaki, Shiro Ishida and Yoshiro Okano
- Journal Title
  
  Natural Science Research
  
  Volume: Vol. 25, No. 1 Pages: 1-6
- NAID
  110008761209
- URL
  http://web.ias.tokushima-u.ac.jp/bulletin/nat/nat25-1-1.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Putative role of intracellular Zn^<2+> release during oxidative stress : A trigger to restore cellular thiol content that is decreased by oxidative stress2011
- Author(s)
  Akio Kinazaki, Hongqin Chen, Kazuki Koizumi, Takuya Kawanai, Tomohiro Oyama, Masaya Satoh, Shiro Ishida, Yoshiro Okano, Yasuo Oyama
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: Vol. 61, No. 5 Issue: 5 Pages: 403-409
- DOI
  10.1007/s12576-011-0160-0
- NAID
  10029575751
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Zinc-pyrithione exerts diverse actions on human leukemia K562 cells : A preliminary study on hormetic action2011
- Author(s)
  Yosuke Endo, Zhehao Han, Jun Kurochi, Masahiro Sakata, Akinori Maetaka, Takayasu Yonezawa, Kazuki Koizumi, Yasuo Oyama
- Journal Title
  
  Natural Science Research
  
  Volume: Vol. 25, No. 3 Pages: 15-19
- NAID
  110008761219
- URL
  http://web.ias.tokushima-u.ac.jp/bulletin/nat/nat25-3-1.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Elevation of intracellular Ca^<2+> level by triclosan in rat thymic lymphocytes : Increase in membrane Ca^<2+> permeability and induction of intracellular Ca^<2+> release2011
- Author(s)
  Ikumi Tamura, Minoru Saito, Yumiko Nishimura, Masaya Satoh, Hiroshi Yamamoto and Yasuo Oyama
- Journal Title
  
  Journal of Health Science
  
  Volume: Vol. 57, No. 6 Pages: 540-546
- NAID
  130001869871
- URL
  http://jhs.pharm.or.jp/data/57(6)/57_540.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Tetracaine decreases intracellular Zn^<2+> concentration by inhibiting Zn^<2+> influx in rat thymocytes2011
- Author(s)
  Kaori Kimura, Yumiko Nishimura, Keisuke Oyama, Takuya Kawanai, Erika Hashimoto, Yasuo Oyama
- Journal Title
  
  Natural Science Research
  
  Volume: Vol. 25, No. 2 Pages: 7-13
- NAID
  110008761213
- URL
  http://web.ias.tokushima-u.ac.jp/bulletin/nat/nat25-2-1.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078
[Journal Article] Some characteristics of membrane Cd^<2+> transport in rat thymocytes: An analysis using Fluo-32011
- Author(s)
  Takuya Kawanai, Masahiro Fujinaga, Kazuki Koizumi, Isao Kurotani, Erika Hashimoto, Masaya Satoh, Shoji Imai, Norikazu Miyoshi, Yasuo Oyama
- Journal Title
  
  Biometals
  
  Volume: Vol. 24, No. 5 Issue: 5 Pages: 903-914
- DOI
  10.1007/s10534-011-9444-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510078

1. AKAIKE Norio (30040182)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. NAKAYE Toshio (20155659)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. TOKUTOMI Naofumi (30227582)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TOMIYOSHI Fukiyo (20035819)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KANEMARU Kaori (00243676)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 津田泰夫 (20036495)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 池本清海 (90091272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Masuda Akiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 増田俊哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 横井川久己男

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
11. 石橋仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OYAMA Yasuo 小山 保夫

Research Projects

Research Products

Co-Researchers

Effects of zinc ion on the cytotoxicity of chemicalsPrincipal Investigator

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toxicolgical role of Zn2+ in cell death induced by chemical stressPrincipal Investigator

Principal Investigator

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Analysis on various toxic actions of organotins including tri-n-butyltinPrincipal Investigator

Principal Investigator

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Amyloid β-protein fragmentによる細胞膜の透過性の解析Principal Investigator

Principal Investigator

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Research Institution

Cytometric analysis on roganometal-induced increase in intracellular Ca

Principal Investigator

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Evaluation on neurotoxicity using dissociated mammalian CNS neuronsPrincipal Investigator

Principal Investigator

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Research Institution

Interaction of various-non-steroidal anti-inflammatories and quinolone antimicrobials on GABA response in rat dissociated hippocampal pyramidal neurons

Principal Investigator

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Research Category

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Research Institution

細胞内遊離CaイオンによるGABA受容器・CCチャネル複合体の制御機構

Principal Investigator

Project Period (FY)

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Research Institution

Macro- and microscopic analysis of glycine-gated response in isolated CNS neurons.

Principal Investigator

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Research Institution

[Journal Article] Modification of cell vulnerability to oxidative stress by N-(3-oxododecanoyl)-L-homoserine-lactone, a quorum sensing molecule, in rat thymocytes2019

Author(s)

Journal Title

DOI

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Data Source

[Journal Article] Membrane hyperpolarization and depolarization of rat thymocytes by azoxystrobin, a post harvest fungicide2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Captan-induced increase in the concentrations of intracellular Ca2+ and Zn2+ and its correlation with oxidative stress in rat thymic lymphocytes2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Conflicting actions of 4-vinylcatechol in rat lymphocytes under oxidative stress induced by hydrogen peroxid2018

Author(s)

Journal Title

DOI

NAID

OYAMA Yasuo 小山保夫