WATANABE TSUYOSHI 渡部剛

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WATANABE Tsuyoshi 渡部剛

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Researcher Number	80220903
Other IDs
Affiliation (Current)	2025: 旭川医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2014 – 2023: 旭川医科大学, 医学部, 教授 2010 – 2012: 旭川医科大学, 医学部, 教授 2000 – 2008: 旭川医科大学, 医学部, 教授 1999 – 2000: 大阪大学, 医学系研究科, 助教授 1995 – 1998: 大阪大学, 医学部, 助教授 1993 – 1994: 筑波大学, 基礎医学系, 講師
Review Section/Research Field	Principal Investigator General anatomy (including Histology/Embryology) / General anatomy (including Histology/Embryology) / General anatomy (including histology/embryology) / Basic Section 48010:Anatomy-related Except Principal Investigator General anatomy (including Histology/Embryology) / Nerve anatomy/Neuropathology / Functional biochemistry / Chemical biology / General anatomy (including Histology/Embryology)
Keywords	Principal Investigator 分泌顆粒 / 免疫組織化学 / 性腺刺激ホルモン産生細胞 / 下垂体前葉 / セクレトグラニン / クロモグラニン / 内分泌細胞 / 電子顕微鏡観察 / ゴルジ装置 / 雌雄差 … More / グラニン蛋白 / ホルモン分泌調節 / Yeast two hybrid system / 細胞内小胞輸送 / 分泌顆粒形成 / コルヒチン / 細胞極性 / 中心小体 / 微小管 / 電子顕微鏡 / 遺伝子導入法 / 視床下部 / 下垂体後葉 / 生活習慣病 / ストレス応答 / 膵島β細胞 / プロセシング / crinophagy / 細胞・組織 / 精子形成 / クリノファジー / 曲精細管上皮 / GnRH誘導体 / 視床下部-下垂体-精巣系 / sex steroids / gonadotropes / sex-related difference / gonadotropins / immunocytochemistry / DNA microarray / secretory granules / anterior pituitary / 性ステロイド / DNAマイクロアレイ / rat / immunocyto chemistry / endocrine cells / sorting mechanism / Secretory granules / Secretogranin / Chromogranin / 蛋白間相互作用 / ペプチドホルモン / Yeast Two Hybrid / 免疫組織化学法 / セクレトグラニンIII / クロモグラニンA / 蛋白選別輸送 / グラニン蛋白群 / Yeast-two hybrid法 / Yeast two hybrid法 / セレクトグラニン / ラット / 選別輸送機構 / セクトレグラニン / ホルモン分泌 / 分泌経路 / 実験内分泌学 / 分泌細胞 / 微小管構築 / 甲状腺濾胞上皮細胞 / 実験内分泌学的動物モデル / ホルモン療法 / 粗面小胞体 / 細胞内膜系小器官 / leuprorelin / LHRH誘導体 / ステロイドホルモン / GFP / ソーティングシグナル / エストラジオール / テストステロン / 蛋白分泌経路 / 性腺刺激ホルモン / ホルモン分泌機構 … More Except Principal Investigator 分泌顆粒 / アポトーシス / PC12細胞 / コレステロール / カテプシンD / カテプシンB / リソソーム / secretogranins / chromogranins / immunocytochemistry / secretory granules / anterior pituitary / セクレトグラニン / クロモグラニン / 免疫組織化学 / 下垂体前葉 / PCTF35 / bcl-2 / 神経栄養因子 / グラニンタンパク質 / 内分泌細胞 / プロテアーゼインヒビター / リソゾーム / NASH / イリジウム錯体 / 非アルコール性脂肪性肝炎 / イメージング / GM1 ganglioside / cholesterol / lipid rafts / GM1ガングリオシド / 脂質ラフト / sexual maturation / gonadotropes / postnatal development / 細胞分化 / 甲状腺刺激ホルモン産生細胞 / プロラクチン産生細胞 / 性成熟 / 性腺刺激ホルモン産生細胞 / 生後発達 / Secretion / Induction / Primary culture / TGF-b1 / Glyosis / Astrocytes / Brain injuries / NGF / 神経突起 / 神経細胞死 / 脊髄後根神経節 / ラット新生仔 / 錐体神経細胞 / 海馬CA1領域 / 低酸素虚血障害 / 栄養因子 / TGFB1 / 分泌 / 発現誘導 / 初代培養 / TGFβ1 / グリオーシス / アストログリア / 脳障害 / Confocal laser scanning microscopy / Exocine / Intercellular Ca^<2+> wave / Photodamage / Nitric oxide / Intranuclear Ca^<2+> dynamics / Intracellular Ca^<2+> dynamics / Tissue bioimaging / ATP / フリーラディカル / 生組織・細胞標本 / 画像解析 / 細胞核内カルシウムイオン / 細胞内カルシウムイオン / 共焦点レーザー顕微鏡 / 外分泌 / 細胞間カルシウム伝播 / 光障害 / 一酸化窒素 / 核内カルシウム動態 / 細胞内カルシウム動態 / 組織バイオイメージング / Dorsal roof ganglion / Lysosomes / Cathepsin D / Cathepsin B / Neurotrophic factor / Bcl-2 gene / PC12 Cells / Apoptosis / CAl錐体細胞 / オートファジ- / 脳虚血 / nedd-2 / cDNAクローニング / 遺伝子導入 / bcl-2遺伝子 / 後根神経節 / bc1-2遺伝子 / ホルモン分泌 / 膜脂質組成 / ペプチドホルモン / セクレトグラニンIII / ホルモンと生理活性物質 / マンノース6-リン酸リセプター / オートファジー / アンチセンス / 海馬CA1錐体細胞 / アスパルギン酸プロテ-ゼ / システインプロテアーゼ / 自食小胞 / CPP32 Less

Physiological significance of the granin protein family in the endocrine function, revealed by analyzing the phenotypes of newly established Sg2- and Sg3-deficient mice.Principal Investigator
- Principal Investigator
  
  Watanabe Tsuyoshi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Asahikawa Medical College
A novel experimental framework by using GnRH analogues to clarify the intracellular degradation processes of organelle outdated in their target cells/organs.Principal Investigator
- Principal Investigator
  
  Watanabe Tsuyoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Asahikawa Medical College
non-alcoholic steatohepatitis imaging with iridium cpmplexes
- Principal Investigator
  
  Hosaka Masahiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemical biology
- Research Institution
  Akita Prefectural University
Diversity in the global organization of the Golgi apparatus in differentiated secretory cells.Principal Investigator
- Principal Investigator
  
  WATANABE Tsuyoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Asahikawa Medical College
Study for protein binding to the cholesterol-rich secretory granule membrane in neuroendocrine cells
- Principal Investigator
  
  HOSAKA Masahiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Akita Prefectural University
The cholesterol metabolism of neuroendocrine cells and crosstalk of the hormone secretion
- Principal Investigator
  
  HOSAKA Masahiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Akita Prefectural University
  Gunma University
Characteristics in the overall organization and dynamics of the Golgi apparatus in the anterior pituitary endocrine cells.Principal Investigator
- Principal Investigator
  
  WATANABE Tsuyoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Asahikawa Medical College
Effects of LHRH analogues on the ultrastructure of male rat pituitary gonadotropesPrincipal Investigator
- Principal Investigator
  
  WATANABE Tsuyoshi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Asahikawa Medical College
Roles of the lipid raft-like microdomain in the secretory granule biogenesis within endocrine cells.
- Principal Investigator
  
  SAKAI Yuko
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Asahikawa Medical College
cDNA microarray analyses on the gene expression in the pituitary glands under the physiological and experimental conditions.Principal Investigator
- Principal Investigator
  
  WATANABE Tsuyoshi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Asahikawa Medical College
Analyzes of the diversity of secretory granules in the anterior pituitary endocrine cells.
- Principal Investigator
  
  SAKAI Yuko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Asahikawa Medical College
Visualization of intracellular signalling in living tissue: Application of real-time confocal microscopy
- Principal Investigator
  
  SATO Yoh-ichi
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Iwate Medical University
MOLECULAR CELL BIOLOGICAL SYUDY OF A NOVEL NEUROTROPHIC PROTEIN, PCTF35
- Principal Investigator
  
  UCHIYAMA Yasuo
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Osaka University
Analyses on the secretory granule formation by using a yeast two hybrid systemPrincipal Investigator
- Principal Investigator
  
  WATANABE Tsuyoshi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Asahikawa Medical College
  Osaka University
リソゾームカテプシン群による神経細胞死の新たな制御機構について
- Principal Investigator
  
  内山安男
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
リソゾームカテプシン群による神経細胞死の新たな制御機構について
- Principal Investigator
  
  内山安男
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
性ステロイドホルモン投与実験動物モデルを用いた分泌顆粒形成機構の解析Principal Investigator
- Principal Investigator
  
  渡部剛
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Osaka University
原型癌遺伝子bcl-2の遺伝子発現による神経細胞死の回避とその生理的意義
- Principal Investigator
  
  UCHIYAMA Yasuo
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
GFP融合蛋白を用いた分泌顆粒形成機構および放出機構の解析Principal Investigator
- Principal Investigator
  
  渡部剛
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Osaka University
遺伝子導入法を用いたクロモグラニン・セクレトグラニン蛋白群の機能解析Principal Investigator
- Principal Investigator
  
  渡部剛
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Osaka University
Apoptosis of CA1 pyramidal neurons in the hippocampus after brief forebrain ischemia and its prevention
- Principal Investigator
  
  UCHIYAMA Yasuo
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Osaka University
下垂体性腺刺激ホルモン産生細胞における蛋白分泌機構の雌雄差に関する研究Principal Investigator
- Principal Investigator
  
  渡部剛
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  University of Tsukuba
ラット下垂体性腺刺激ホルモン産生細胞における蛋白分泌経路の免疫組織科学的研究Principal Investigator
- Principal Investigator
  
  渡部剛
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  University of Tsukuba

[Journal Article] Optimizing the reaction temperature to facilitate an efficient osmium maceration procedure2020
- Author(s)
  Koga D, Kusumi S, Watanabe T.
- Journal Title
  
  Biomed Res.
  
  Volume: 41 Issue: 4 Pages: 161-168
- DOI
  10.2220/biomedres.41.161
- NAID
  130007887495
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07261, KAKENHI-PUBLICLY-20H04896, KAKENHI-PROJECT-20H03411
[Journal Article] Culture in 10% O2 enhances the production of active hormones in neuro-endocrine cells by up-regulating the expression of processing enzymes2019
- Author(s)
  Sato E, Maeda Y, Sato Y, Hinata A, Gomi H, Koga D, Torii S, Watanabe T, Hosaka M
- Journal Title
  
  Biochem. J.
  
  Volume: 476 Issue: 5 Pages: 827-842
- DOI
  10.1042/bcj20180832
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08458, KAKENHI-PROJECT-17K08528, KAKENHI-PROJECT-18K05443, KAKENHI-PROJECT-16K08078, KAKENHI-PROJECT-17K08505
[Journal Article] Differential effects of depot formulations of GnRH agonist leuprorelin and antagonist degarelix on the seminiferous epithelium of the rat testis 2018
- Author(s)
 Hori J, Koga D, Kakizaki H, Watanabe T
- Journal Title
 
 Biomed. Res.
 
 Volume: 39 Issue: 4 Pages: 197-214
- DOI
 10.2220/biomedres.39.197
- NAID
 130007432831
- ISSN
 0388-6107, 1880-313X
- Year and Date
 2018-08-01
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-16K08458, KAKENHI-PROJECT-17K08505
[Journal Article] Backscattered electron imaging of resin-embedded sections2018
- Author(s)
  Koga D, Kusumi S, Watanabe T
- Journal Title
  
  Microscopy
  
  Volume: 67 Issue: 4 Pages: 196-206
- DOI
  10.1093/jmicro/dfy028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08458, KAKENHI-PROJECT-17K08505
[Journal Article] Impaired processing of prohormones in secretogranin III null mice causes maladaptation to an inadequate diet and stress.2018
- Author(s)
  Yoshinori Maeda, Saki Kudo, Ken Tsushima, Eri Sato, Chisato Kubota, Aika Kayamori, Hiroki Bochimoto, Daisuke Koga, Seiji Torii, Hiroshi Gomi, Tsuyoshi Watanabe, Masahiro Hosaka
- Journal Title
  
  Endocrinology
  
  Volume: 159 Issue: 2 Pages: 1213-1227
- DOI
  10.1210/en.2017-00636
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08078, KAKENHI-PROJECT-16K08458, KAKENHI-PROJECT-17K08505, KAKENHI-PROJECT-17K08528, KAKENHI-PROJECT-15K18951, KAKENHI-PROJECT-17J40226
[Journal Article] Integrative method for three-dimensional imaging of the entire Golgi apparatus by combining thiamine pyrophosphatase cytochemistry and array tomography using backscattered electron-mode scanning electron microscopy 2017
- Author(s)
 Koga D, Kusumi S, Ushiki T and Watanabe T
- Journal Title
 
 Biomed. Res.
 
 Volume: 38 Issue: 5 Pages: 285-296
- DOI
 10.2220/biomedres.38.285
- NAID
 130006179815
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-16K08458, KAKENHI-PROJECT-17K08505
[Journal Article] Novel scanning electron microscopy methods for analyzing the 3D structure of the Golgi apparatus.2017
- Author(s)
  Koga D, Ushiki T, Watanabe T
- Journal Title
  
  Anat Sci Int
  
  Volume: 92 Issue: 1 Pages: 37-49
- DOI
  10.1007/s12565-016-0380-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460263
[Journal Article] Changes in the three-dimensional ultrastructure of membranous organelles in male rat pituitary gonadotropes after castration2017
- Author(s)
 Koga D, Bochimoto H, Kusumi S, Ushiki T, Watanabe T
- Journal Title
 
 Biomed. Res.
 
 Volume: 38 Issue: 1 Pages: 1-18
- DOI
 10.2220/biomedres.38.1
- NAID
 130005242939
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-26460263, KAKENHI-PROJECT-26860128, KAKENHI-PROJECT-16K08458, KAKENHI-PROJECT-15K18951
[Journal Article] Expression of Secretogranin III in Chicken Endocrine Cells: Its Relevance to the Secretory Granule Properties of Peptide Prohormone Processing and Bioactive Amine Content.2015
- Author(s)
  Gomi H, Morikawa S, Shinmura N, Moki H, Yasui T, Tsukise A, Torii S, Watanabe T, Maeda Y, Hosaka M
- Journal Title
  
  J Histochem Cytochem
  
  Volume: 印刷中 Issue: 5 Pages: 350-366
- DOI
  10.1369/0022155415575032
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390050, KAKENHI-PROJECT-25440052, KAKENHI-PROJECT-25450471
[Journal Article] Correlative Light and Scanning Electron Microscopy for Observing the Three-Dimensional Ultrastructure of Membranous Cell Organelles in Relation to their Molecular Components.2015
- Author(s)
  Koga D, Kusumi S, Bochimoto H, Watanabe T, Ushiki T
- Journal Title
  
  J Histochem Cytochem
  
  Volume: 63 Issue: 12 Pages: 968-979
- DOI
  10.1369/0022155415609099
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460263, KAKENHI-PROJECT-15K18951, KAKENHI-PROJECT-26860128
[Journal Article] Functional Implications of the Golgi and Microtubular Network in Gonadotropes2014
- Author(s)
  ②Watanabe T, Bochimoto H, Koga D, Hosaka M, Ushiki T
- Journal Title
  
  Molecular and Cellular Endocrinology
  
  Volume: vol.385(1-2) Issue: 1-2 Pages: 88-96
- DOI
  10.1016/j.mce.2013.10.003
- NAID
  120005496543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890012, KAKENHI-PROJECT-25440052
[Journal Article] Functional Implications of the Golgi and Microtubular Network in Gonadotropes.2014
- Author(s)
  Watanabe, T., Bochimoto, H., Koga, D., Hosaka, M., Ushiki, T.
- Journal Title
  
  Mol Cell Endocrinol.
  
  Volume: 385 Pages: 88-96
- NAID
  120005496543
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25440052
[Journal Article] Multiple sorting systems for secretory granules ensure the regulated secretion of peotide hormones2013
- Author(s)
  Sun, M., Watanabe, T., Bochimoto, H., Sakai, Y., Torii, S., Takeuchi, T., Hosaka, M.
- Journal Title
  
  Traffic
  
  Volume: 14 Pages: 205-218
- Data Source
  KAKENHI-PROJECT-22570133
[Journal Article] Multiple sorting systems for secretory granules ensure the regulated secretion of peptide hormones.2013
- Author(s)
  Sun M
- Journal Title
  
  Traffic
  
  Volume: 14 Issue: 2 Pages: 205-218
- DOI
  10.1111/tra.12029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689007, KAKENHI-PROJECT-22570133, KAKENHI-PROJECT-22590185, KAKENHI-PROJECT-24890012, KAKENHI-PROJECT-25440052
[Journal Article] A unique ball-shaped Golgi apparatus in the rat pituitary gonadotrope: its functional implications in relation to the arrangement of the microtubule network.2012
- Author(s)
  Watanabe T, Sakai Y, Koga D, Bochimoto H, Hira Y, Hosaka M, Ushiki T.
- Journal Title
  
  J Histochem Cytochem.
  
  Volume: 60 Issue: 8 Pages: 588-602
- DOI
  10.1369/0022155412448791
- NAID
  120006522770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570133, KAKENHI-PROJECT-22590185
[Journal Article] A unique ball-shapeed Golgi apparatus in the rat pituitary ganadotrope: its functional implications in relation to the arrangement of microtuble network2012
- Author(s)
  Watanabe, T., Sakai, Y., Koga, D., Bochimoto, H., Hira, Y., Hosaka, M., Ushiki, T.
- Journal Title
  
  J. Histochem. Cytochem
  
  Volume: 60 Pages: 588-602
- Data Source
  KAKENHI-PROJECT-22570133
[Journal Article] A unique ball-shaped Golgi apparatus in the rat pituitary gonadotrope : its functional implications in relation to the arrangement of the microtubule network2012
- Author(s)
  Watanabe T, et al.
- Journal Title
  
  J Histochem Cytochem
  
  Volume: 60(in press)
- NAID
  120006522770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590185
[Journal Article] Secretogranin lll : a bridge between core homone aggregates and the secretory granule membrane.2010
- Author(s)
  Hosaka M, Watanabe T
- Journal Title
  
  Endocrine J
  
  Volume: 57 Pages: 275-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570133
[Journal Article] Secretogranin III: a Bridge between Core Hormone Aggregates and the Secretory Granule Membrane2010
- Author(s)
  Hosaka M, Watanabe T
- Journal Title
  
  Endocr J
  
  Volume: 57 Issue: 4 Pages: 275-286
- DOI
  10.1507/endocrj.K10E-038
- NAID
  10029584142
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590185
[Journal Article] Secretograin lll : a bridge between core hormone aggregates and the secretory granule membrane2010
- Author(s)
  Hosaka M, Watanabe T
- Journal Title
  
  Endocrine J
  
  Volume: 57 Pages: 275-286
- Data Source
  KAKENHI-PROJECT-22590185
[Journal Article] Secretogranin III: a bridge between core hormone aggregates and the secretory granule membrane2010
- Author(s)
  Hosaka M, Watanabe T
- Journal Title
  
  Endocrine J
  
  Volume: 57 Pages: 275-286
- NAID
  10029584142
- Data Source
  KAKENHI-PROJECT-22570133
[Journal Article] 内分泌細胞における分泌顆粒形成機構2008
- Author(s)
  渡部剛、阪井裕子、他
- Journal Title
  
  顕微鏡 43(印刷中)
- NAID
  10021151701
- Data Source
  KAKENHI-PROJECT-17590144
[Journal Article] 内分泌細胞における分泌顆粒形成機構2008
- Author(s)
  渡部剛、阪井裕子, 他
- Journal Title
  
  顕微鏡 43
  
  Pages: 29-34
- NAID
  10021151701
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590144
[Journal Article] 内分泌細胞における分泌顆粒形成機構2008
- Author(s)
  渡部剛、阪井裕子、平義樹、暮地本宙己、穂坂正博
- Journal Title
  
  顕微鏡 43
  
  Pages: 29-34
- NAID
  10021151701
- Data Source
  KAKENHI-PROJECT-18590177
[Journal Article] Molecular and cellular basis for the secretory granule biogenesis in endocrine cells.2008
- Author(s)
  Watanabe T, Sakai Y, Hira Y, Bochimoto H, and Hosaka M
- Journal Title
  
  Kenbikyo (in Japanese) 43
  
  Pages: 29-34
- NAID
  10021151701
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590144
[Journal Article] 内分泌細胞における分泌穎粒形成機構2008
- Author(s)
  渡部剛, 他
- Journal Title
  
  顕微鏡 43
  
  Pages: 29-34
- Data Source
  KAKENHI-PROJECT-18590177
[Journal Article] A subset of p23 localized on secretory granules in pancreatic β-cells.2007
- Author(s)
  Hosaka M, Watanabe T, Yamauchi Y, Sakai Y, Suda M, Mizutani S, Takeuchi T, Isobe T, Izumi T
- Journal Title
  
  J Histochem Cytochem 55
  
  Pages: 235-245
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590144
[Journal Article] Effects of adepot formulation of the GnRH agonist leuprorelin on the ultrastructure of male rat pituitary gonadotropes2007
- Author(s)
  Kitahara K, Sakai Y, Hosaka M, Hira Y,Kakizaki H, Watanabe T
- Journal Title
  
  Arch Histol Cytol 70
  
  Pages: 79-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590177
[Journal Article] Effects of a depot formulation of the GnRH agonist leuprorelin on the ultrastructure of male rat pituitary gonadotropes.2007
- Author(s)
  Kitahara K, Sakai Y, Hosaka M, Hira Y, Kakizaki H, Watanabe T
- Journal Title
  
  Arch Histol Cytol 70
  
  Pages: 79-93
- NAID
  10019550961
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590144
[Journal Article] Interaction between secretogranin III and carboxypeptidase E facilitates prohormone sorting within secretory granules.2005
- Author(s)
  Hosaka M, Watanabe T, Sakai Y, Kato T, Takeuchi T
- Journal Title
  
  J Cell Sci 118
  
  Pages: 4785-4795
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590144
[Journal Article] Addition of phosphotungstic acid to ethanol for dehydration improves both the ultrastructure and antigenicity of pituitary tissue embedded in LR White acrylic resin.2005
- Author(s)
  Sakai Y, Hosaka M, Hira Y, Watanabe T
- Journal Title
  
  Arch Histol Cytol 68
  
  Pages: 337-347
- NAID
  10017244286
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590144
[Journal Article] Addition of phosphotungstic acid to ethanol for dehydration improves both the infrastructure and antigenicity of pituitary tissue embedded in LR White acrylic resin.2005
- Author(s)
  Sakai Y, Hosaka M, Hira Y, Watanabe T
- Journal Title
  
  Arch Histol Cytol 68
  
  Pages: 337-347
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590152
[Journal Article] Interaction between secretogranin III and carboxypeptidase E facilitates prohormone sorting within secretory granules.2005
- Author(s)
  Hosaka M, Watanabe T, Sakai Y, Kato T, Takeuchi T
- Journal Title
  
  J Cell Sci 118
  
  Pages: 4785-4795
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590152
[Journal Article] Immunocytochemical localization of secretogranin III in the endocrine pancreas of male rats.2004
- Author(s)
  Sakai Y, Hosaka M, Yoshinaga A, Hira Y, Harumi T, Watanabe T
- Journal Title
  
  Arch Histol Cytol 67
  
  Pages: 57-64
- NAID
  10012846445
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570001
[Journal Article] Immunocytochemical localization of secretogranin III in the endocrine pancreas of male rats.2004
- Author(s)
  Sakai Y, Hosaka M, Yoshinaga A, Hira Y, Harumi T, Watanabe T
- Journal Title
  
  Arch Histol Cytol 67
  
  Pages: 57-64
- NAID
  10012846445
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590152
[Journal Article] Secretogranin III binds to cholesterol in the secretory granule membrane as an adapter for chromogranin A.2004
- Author(s)
  Hosaka M, Suda M, Sakai Y, Izumi T, Watanabe T, Takeuchi T
- Journal Title
  
  J Biol Chem 279
  
  Pages: 3627-3634
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590152
[Journal Article] Secretogranin III binds to cholesterol in the secretory granule membrane as an adapter for chromogranin A.2004
- Author(s)
  Hosaka M, Suda M, Sakai Y, Izumi T, Watanabe T, Takeuchi T
- Journal Title
  
  J Biol Chem 279
  
  Pages: 3627-3634
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570001
[Journal Article] Immunocytochemical localization of secretogranin III in the anterior lobe of male rat pituitary glands.2003
- Author(s)
  Sakai Y, Hosaka M, Hira Y, Harumi T, Ohsawa Y, Wang H, Takeuchi T, Uchiyama Y, Watanabe T
- Journal Title
  
  J Histochem Cytochem 51
  
  Pages: 227-238
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570001
[Journal Article] Identification of a chromogranin A domain that mediates binding to secretogranin III and targeting to secretory granules in pituitary cells and pancreatic β-cells.2002
- Author(s)
  Hosaka M, Watanabe T, Sakai Y, Uchiyama Y, Takeuchi T
- Journal Title
  
  Mol Biol Cell 13
  
  Pages: 3388-3399
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570001
[Journal Article] A unique ball-shapeed Golgi apparatus in the rat pituitary ganadotrope : its functional implications in relation to the arrangement of microtuble network
- Author(s)
  Watanabe, T., Sakai, Y., Koga, D., Bochimoto, H., Hira, Y., Hosaka, M., Ushiki, T.
- Journal Title
  
  J.Histochem.Cytochem.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570133
[Journal Article] Sustained treatment with a GnRH agonist (leuprorelin) affects the ultrastructural characteristics of membranous organelles in male rat pituitary gonadotropes
- Author(s)
  Bochimoto H, Koga D, Sakai Y, Hira Y, Hosaka M, Ushiki T, Watanabe T
- Journal Title
  
  Arch Histol Cytol
  
  Volume: (in press)
- NAID
  130005087927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590185
[Presentation] 分泌顆粒へのホルモン輸送機構が冗長性を持つ意義:生活習慣病の危険因子としてのグラニンタンパク質不全2024
- Author(s)
  穂坂正博、五味浩司、渡部剛
- Organizer
  先端モデル動物支援プラットフォーム成果発表会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03411
[Presentation] セクレトグラニンが制御する下垂体前葉ホルモンの分泌/産生2023
- Author(s)
  河田秋音、平島優花、五味浩司、渡部剛、穂坂正博
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20H03411
[Presentation] インスリン分泌でセクレトグラニンが果たす役割2023
- Author(s)
  平島優花、河田秋音、五味浩司、渡部剛、穂坂正博
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20H03411
[Presentation] コルヒチン脳室内投与ラットの視床下部神経分泌細胞におけるグラニン蛋白発現部位の同定2022
- Author(s)
  森永涼介、甲賀大輔、穂坂正博、渡部剛
- Organizer
  日本解剖学会第68回東北・北海道連合支部学術集会
- Data Source
  KAKENHI-PROJECT-20H03411
[Presentation] 視床下部下垂体系におけるグラニン蛋白の局在と機能的意義2022
- Author(s)
  森永涼介、甲賀大輔、穂坂正博、渡部剛
- Organizer
  日本解剖学会第127回総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-20H03411
[Presentation] 視床下部-下垂体系におけるグラニン蛋白の発現パターンの差異2021
- Author(s)
  森永涼介、甲賀大輔、穂坂正博、渡部剛
- Organizer
  日本解剖学会第67回東北・北海道連合支部学術集会
- Data Source
  KAKENHI-PROJECT-20H03411
[Presentation] 視床下部-下垂体後葉系で発現するグラニン蛋白2021
- Author(s)
  森永涼介、渡部剛
- Organizer
  第126回日本解剖学会全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20H03411
[Presentation] セクレトグラニンIII欠損マウスにおいて高脂肪/高糖質食負荷時に顕在化する耐糖能異常2021
- Author(s)
  渡部剛、甲賀大輔、森永涼介、穂坂正博
- Organizer
  第126回日本解剖学会全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20H03411
[Presentation] 分泌動線とゴルジ装置の大局的構造を指標とした分泌細胞の類型化2019
- Author(s)
  渡部剛、甲賀大輔
- Organizer
  日本顕微鏡学会北海道支部学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08505
[Presentation] セクレトグラニンIII (SgIII) ノックアウトマウスで見られた内分泌学的ストレスに対する脆弱性2019
- Author(s)
  渡部剛、甲賀大輔、穂坂正博
- Organizer
  第65回日本解剖学会東北・北海道連合支部学術集会
- Data Source
  KAKENHI-PROJECT-17K08505
[Presentation] GnRH agonistとantagonist持続投与により生じるラット曲精細管の組織学的変化の比較2018
- Author(s)
  渡部剛、堀淳一、柿崎秀宏、甲賀大輔
- Organizer
  第123回日本解剖学会全国学術集会
- Data Source
  KAKENHI-PROJECT-17K08505
[Presentation] 連続切片SEM法による内分泌細胞ゴルジ装置の3D構造解析2017
- Author(s)
  甲賀大輔、久住聡、柴田昌宏、渡部剛
- Organizer
  日本解剖学会第122回全国学術集会
- Place of Presentation
  長崎市
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-26460263
[Presentation] GnRH誘導体持続投与により生じるラット曲精細管の組織学的変化2017
- Author(s)
  渡部剛、堀淳一、柿崎秀宏、甲賀大輔
- Organizer
  第63回日本解剖学会東北・北海道連合支部学術集会
- Data Source
  KAKENHI-PROJECT-17K08505
[Presentation] ゴルジ装置の大局的構造と分泌動線から見た分泌細胞の類型化の試み2016
- Author(s)
  渡部剛、暮地本宙己、甲賀大輔
- Organizer
  日本解剖学会　第121回全国学術集会
- Place of Presentation
  郡山市
- Year and Date
  2016-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-26460263
[Presentation] GnRH antagonist 持続投与による下垂体前葉性腺刺激ホルモン産生細胞の微細構造変化2016
- Author(s)
  堀淳一、暮地本宙己、甲賀大輔、柿崎秀宏、渡部剛
- Organizer
  日本解剖学会第62回東北・北海道連合支部学術集会
- Place of Presentation
  帯広市
- Year and Date
  2016-09-03
- Data Source
  KAKENHI-PROJECT-26460263
[Presentation] セクレトグラニンIIIが膵島インスリン生合成と分泌で果たす役割について2015
- Author(s)
  前田佳紀、工藤咲希、暮地本宙己、村田知里、鳥居征司、渡部剛、穂坂正博
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25440052
[Presentation] 脳下垂体内分泌細胞の低酸素環境におけるホルモン分泌の解析2015
- Author(s)
  佐藤瑛理、前田佳紀、暮地本宙己、渡部剛、穂坂正博
- Organizer
  第81回日本生化学会東北支部例会
- Place of Presentation
  仙台
- Year and Date
  2015-05-09
- Data Source
  KAKENHI-PROJECT-25440052
[Presentation] セクレトグラニンIIIが生体のインスリン生合成と分泌で果たす役割2015
- Author(s)
  前田佳紀、工藤咲希、暮地本宙己、村田知里、鳥居征司、渡部剛、穂坂正博
- Organizer
  第81回日本生化学会東北支部例会
- Place of Presentation
  仙台
- Year and Date
  2015-05-09
- Data Source
  KAKENHI-PROJECT-25440052
[Presentation] Ring-shaped Golgi apparatus observed in the epithelial cells of rat thyroid follicles.2015
- Author(s)
  渡部　剛、暮地本宙己
- Organizer
  第120回日本解剖学会総会・全国学術集会/第92回日本生理学会大会　合同大会
- Place of Presentation
  神戸国際会議場・展示場、神戸
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-26460263
[Presentation] 脳下垂体内分泌細胞の低酸素環境におけるACTH分泌について2015
- Author(s)
  佐藤瑛理、前田佳紀、暮地本宙己、渡部剛、穂坂正博
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25440052
[Presentation] ラット甲状腺濾胞上皮細胞におけるゴルジ装置と微小管の構築2015
- Author(s)
  渡部剛、暮地本宙己、甲賀大輔
- Organizer
  日本解剖学会　第61回東北・北海道連合支部学術集会
- Place of Presentation
  盛岡市
- Year and Date
  2015-08-29
- Data Source
  KAKENHI-PROJECT-26460263
[Presentation] 内分泌細胞の分泌顆粒に局在するセクレトグラニンIIIの役割2014
- Author(s)
  前田佳紀、暮地本宙己、村田知里、鳥居征司、渡部剛、穂坂正博
- Organizer
  第80回生化学会東北支部例会
- Place of Presentation
  秋田
- Year and Date
  2014-05-10
- Data Source
  KAKENHI-PROJECT-25440052
[Presentation] Overall Shape of the Golgi Apparatus and Intracellular Organization of Secretory Cells: The Significance of the Spherical Golgi in the Pituitary Gonadotropes.2014
- Author(s)
  Tsuyoshi Watanabe
- Organizer
  Gordon Research Conference: Protein processing, Trafficking & Secretion
- Place of Presentation
  Colby-Sawyer College, New London, NH, USA
- Year and Date
  2014-07-23
- Invited
- Data Source
  KAKENHI-PROJECT-26460263
[Presentation] 下垂体前葉におけるゴルジ装置構築の多様性2013
- Author(s)
  渡部剛、暮地本宙己
- Organizer
  微小管構築との関連性に着目して」第118回日本解剖学会全国学術集会
- Place of Presentation
  高松
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-22590185
[Presentation] 分泌顆粒形成でセクレトグラニンIIIが果たす役割2013
- Author(s)
  穂坂正博、暮地本宙己、渡部剛
- Organizer
  第28回日本下垂体研究会
- Place of Presentation
  花巻温泉（ホテル千秋閣：岩手）
- Data Source
  KAKENHI-PROJECT-25440052
[Presentation] Multiple sorting systems for the secretory granules ensure the regulated secretion of peptide hormones in endocrine cells2013
- Author(s)
  Masahiro Hosaka, Hiroki Bochimoto, Tsuyoshi Watanabe
- Organizer
  第65回日本細胞生物学会
- Place of Presentation
  ウインクあいち（愛知県産業労働センター；名古屋））
- Data Source
  KAKENHI-PROJECT-25440052
[Presentation] 下垂体前葉におけるゴルジ装置構築の多様性：微小管構築との関連性に着目して2013
- Author(s)
  渡部剛
- Organizer
  第118回日本解剖学会全国学術集会
- Place of Presentation
  高松
- Data Source
  KAKENHI-PROJECT-22590185
[Presentation] GnRH レセプター刺激を受けたラット下垂体前葉性腺刺激ホルモン産生細胞に出現する粗面小胞体の変化2013
- Author(s)
  暮地本宙己、甲賀大輔、穂坂正博、牛木辰男、渡部剛
- Organizer
  第118回日本解剖学会全国学術集会
- Place of Presentation
  高松
- Year and Date
  2013-03-29
- Data Source
  KAKENHI-PROJECT-22590185
[Presentation] ゴルジ装置の構築から見た内分泌細胞と外分泌細胞・組織の比較2012
- Author(s)
  渡部剛、暮地本宙己
- Organizer
  第117回日本解剖学会全国学術集会
- Place of Presentation
  甲府
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-22590185
[Presentation] 様々な分泌刺激に対する細胞内膜系小器官の応答の解析: 下垂体前葉性腺刺激ホルモン産生細胞をモデルとして2012
- Author(s)
  暮地本宙己、甲賀大輔、穂坂正博、牛木辰男、渡部剛
- Organizer
  第117回日本解剖学会全国学術集会・シンポジウム「細胞外シグナルと下垂体細胞の発達、機能発現への形態学的アプローチ」
- Place of Presentation
  甲府
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PROJECT-22590185
[Presentation] ゴルジ装置の構築から見た内分泌細胞と外分泌細胞・組織の比較2012
- Author(s)
  渡部剛, 他
- Organizer
  日本解剖学会第117回全国学術集会
- Place of Presentation
  甲府
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-22590185
[Presentation] 様々な分泌刺激に対する細胞内膜系小器官の応答の解析:下垂体前葉性腺刺激ホルモン産生細胞をモデルとして2012
- Author(s)
  暮地本宙己、甲賀大輔、穂坂正博、牛木辰男、渡部剛
- Organizer
  第117回日本解剖学会総会
- Place of Presentation
  甲府
- Data Source
  KAKENHI-PROJECT-22570133
[Presentation] コルヒチン投与による性腺刺激ホルモン産生細胞(LH/FSH 産生細胞)のゴルジ装置の微細構造変化2012
- Author(s)
  渡部剛、暮地本宙己、穂坂正博
- Organizer
  第58回日本解剖学会東北・北海道連合支部学術集会
- Place of Presentation
  山形
- Year and Date
  2012-09-22
- Data Source
  KAKENHI-PROJECT-22590185
[Presentation] 様々な分泌刺激に対する細胞内膜系小器官の応答の解析:下垂体前葉性腺刺激ホルモン産生細胞をモデルとして2012
- Author(s)
  暮地本宙己、甲賀大輔、穂坂正博、牛木辰男、渡部剛
- Organizer
  第117回日本解剖学会総会
- Place of Presentation
  甲府市
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PROJECT-22570133
[Presentation] コルヒチン投与による性腺刺激ホルモン産生細胞（LH/FSH産生細胞）のゴルジ装置の微細構造変化2012
- Author(s)
  渡部剛
- Organizer
  第58回日本解剖学会東北・北海道連合支部学術集会
- Place of Presentation
  山形
- Data Source
  KAKENHI-PROJECT-22590185
[Presentation] 内分泌細胞の分泌顆粒形成におけるグラニンタンパク質の役割2012
- Author(s)
  穂坂正博, 孫夢, 鳥居征司, 竹内利行, 暮地本宙己, 渡部剛
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22570133
[Presentation] 内分泌細胞の分泌顆粒形成におけるグラニンタンパク質の役割2012
- Author(s)
  穂坂正博, 孫夢, 鳥居征司, 竹内利行, 暮地本宙己, 渡部剛
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-22570133
[Presentation] プロピルチオウラシル(PTU) 投与後のラット下垂体前葉甲状腺刺激ホルモン(TSH) 産生細胞における細胞内膜系小器官の変化2012
- Author(s)
  暮地本宙己、赤木康司、渡部剛
- Organizer
  第58回日本解剖学会東北・北海道連合支部学術集会
- Place of Presentation
  山形
- Year and Date
  2012-09-22
- Data Source
  KAKENHI-PROJECT-22590185
[Presentation] 内分泌細胞の分泌顆粒形成におけるグラニンタンパク質の役割2012
- Author(s)
  穂坂正博、孫夢、暮地本宙己、渡部剛
- Organizer
  第20回秋田応用生命科学研究会
- Place of Presentation
  秋田
- Data Source
  KAKENHI-PROJECT-22570133
[Presentation] AtT20細胞におけるセクレトグフニンIII(SgIII)の発現抑制はトランスゴルジネットワーク(TGN)の空胞化と調節性分泌の部分的障害を誘起する2011
- Author(s)
  渡部剛, 他
- Organizer
  日本解剖学会第57回東北・北海道連合支部学術集会
- Place of Presentation
  盛岡
- Year and Date
  2011-09-10
- Data Source
  KAKENHI-PROJECT-22590185
[Presentation] 去勢刺激を受けた下垂体前葉性腺刺激ホルモン産生細胞(LH/FSH 産生細胞)の微細構造に対するGnRH アゴニスト持続投与の影響2011
- Author(s)
  暮地本宙己、甲賀大輔、阪井裕子、平義樹、牛木辰男、渡部剛
- Organizer
  第57回日本解剖学会東北・北海道連合支部学術集会
- Place of Presentation
  盛岡
- Year and Date
  2011-09-10
- Data Source
  KAKENHI-PROJECT-22590185
[Presentation] 内分泌学細胞の分泌顆粒形成におけるグラニン蛋白の役割2011
- Author(s)
  渡部剛, 他
- Organizer
  日本解剖学会第116回全国学術集会
- Place of Presentation
  横浜(震災のため誌上開催)
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-22590185
[Presentation] AtT-20 細胞におけるセクレトグラニンIII (SgIII) の発現抑制はトランスゴルジネットワーク(TGN) の空胞化と調節性分泌の部分障害を誘起する2011
- Author(s)
  渡部剛、暮地本宙己、穂坂正博
- Organizer
  第57回日本解剖学会東北・北海道連合支部学術集会
- Place of Presentation
  盛岡
- Year and Date
  2011-09-10
- Data Source
  KAKENHI-PROJECT-22590185
[Presentation] GnRH アゴニストを持続投与した去勢術後ラットの下垂体前葉性腺刺激ホルモン産生細胞における細胞内膜系の変化2011
- Author(s)
  暮地本宙己、甲賀大輔、阪井裕子、平義樹、牛木辰男、渡部剛
- Organizer
  第88回日本生理学会大会/第116回日本解剖学会全国学術集会・合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590185
[Presentation] 「内分泌細胞の分泌顆粒形成におけるグラニン蛋白の役割」第88回日本生理学会大会/第116回日本解剖学会全国学術集会・合同大会2011
- Author(s)
  渡部剛、暮地本宙己、穂坂正博
- Organizer
  シンポジウム「内分泌細胞における新たな分泌制御機構と分泌現象」
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590185
[Presentation] 実験内分泌学的アプローチを活用した細胞内過程の解析細胞内輸送と代謝2009
- Author(s)
  渡部剛、阪井裕子、暮地本宙己
- Organizer
  第114回解剖学会全国学術集会シンポジウム
- Place of Presentation
  岡山
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-18590177
[Presentation] 実験内分泌学的アプローチを活用した細胞内過程の解析2009
- Author(s)
  渡部剛, 他
- Organizer
  日本解剖学会第114回全国学術集会
- Place of Presentation
  岡山
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-18590177
[Presentation] ラット下垂体前葉の性腺刺激ホルモン産生細胞におけるゴルジ装置の形態と微小管の走行2008
- Author(s)
  阪井裕子、平義樹、河野透、渡部剛
- Organizer
  第113回解剖学会全国学術集会
- Place of Presentation
  大分・由布市
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-18590177
[Presentation] 内分泌細胞における分泌顆粒形成とそれに係わるグラニン蛋白と脂質ラフトの役割分泌現象と生体膜、そしてその可視化2008
- Author(s)
  渡部剛、阪井裕子、穂坂正博
- Organizer
  第81回日本内分泌学会学術総会シンポジウム
- Place of Presentation
  青森
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-18590177
[Presentation] 遺伝子発現から見た下垂体の雌雄差視床下部-下垂体研究の最前線-新しい発見と新たな概念の提言-2007
- Author(s)
  渡部剛、伊藤恵美、阪井裕子、渡辺慎哉
- Organizer
  第112回解剖学会全国学術集会シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2007-03-27
- Data Source
  KAKENHI-PROJECT-18590177
[Presentation] ラット下垂体前葉における分泌蛋白の品質管理過程の多様性について2007
- Author(s)
  阪井裕子、平義樹、渡部剛
- Organizer
  第112回解剖学会全国学術集会
- Place of Presentation
  大阪
- Year and Date
  2007-03-29
- Data Source
  KAKENHI-PROJECT-18590177
[Presentation] 神経・内分泌細胞における分泌蛋白の動線の再考-ゴルジ装置の極性が示すもの-2006
- Author(s)
  渡部剛、阪井裕子、穂坂正博
- Organizer
  NPO法人綜合画像研究支援・第3回可視化技術ワークショップ
- Place of Presentation
  東京都文京区
- Year and Date
  2006-11-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590144
[Presentation] 神経・内分泌細胞における分泌蛋白の動線の再考-ゴルジ装置の極性が示すもの-平義樹ゴルジ装置と物質輸送のイメージング2006
- Author(s)
  渡部剛、穂坂正博、阪井裕子、平義樹
- Organizer
  NPO法人綜合画像研究支援・第3回可視化技術ワークショップ
- Place of Presentation
  東京
- Year and Date
  2006-11-11
- Data Source
  KAKENHI-PROJECT-18590177
[Presentation] Traffic lines of secretory proteins within neuroendocrine cells.2006
- Author(s)
  Watanabe T, Sakai Y, Hosaka M, Hira Y
- Organizer
  The 3rd Workshop on the Visualization Techniques (by Integrated Imaging Research Support)
- Year and Date
  2006-11-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590144
[Presentation] Roles of granins and lipid rafts in secretory granule biogenesis.2005
- Author(s)
  Watanabe T, Sakai Y, Hosaka M
- Organizer
  The 20th Meeting of the Japan Society for Pituitary Research
- Place of Presentation
  Nago (Okinawa)
- Year and Date
  2005-06-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590144
[Presentation] 内分泌顆粒形成におけるグラニン蛋白と脂質ラフトの役割2005
- Author(s)
  渡部剛、阪井裕子、穂坂正博
- Organizer
  第20回日本下垂体研究会
- Place of Presentation
  沖縄県名護市
- Year and Date
  2005-07-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590144
[Presentation] 内分泌細胞の分泌顆粒形成におけるグラニンタンパク質の役割
- Author(s)
  穂坂正博、暮地本宙己、渡部剛
- Organizer
  第7９回日本生化学会東北支部会例会
- Place of Presentation
  東北大学（仙台）
- Data Source
  KAKENHI-PROJECT-25440052
[Presentation] 神経内分泌細胞の分泌顆粒に局在するセクレトグラニンIIIの生体で果たす役割
- Author(s)
  前田佳紀、暮地本宙己、村田知里、鳥居征司、渡部剛、穂坂正博
- Organizer
  第87回生化学会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25440052
[Presentation] GnRHアゴニスト持続投与によりラットLH/FSH 産生細胞で生じるLH 分泌・産生機能の変化
- Author(s)
  暮地本宙己、穂坂正博、板東良雄、甲賀大輔、平義樹、牛木辰男、渡部剛
- Organizer
  日本解剖学会第60回東北・北海道連合支部学術集会
- Place of Presentation
  福島
- Year and Date
  2014-09-06 – 2014-09-07
- Data Source
  KAKENHI-PROJECT-25440052
[Presentation] 内分泌細胞の分泌顆粒形成におけるグラニンタンパク質の役割
- Author(s)
  穂坂正博、孫夢、暮地本宙己、渡部剛
- Organizer
  第20回秋田応用生命科学研究会
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-22570133

1. HOSAKA Masahiro (80311603)

# of Collaborated Projects: 7 results

# of Collaborated Products: 42 results
2. UCHIYAMA Yasuo (10049091)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. OHSAWA Yoshiyuki (30273642)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. WAGURI Satoshi (30244908)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. SAKAI Yuko (40041826)

# of Collaborated Projects: 3 results

# of Collaborated Products: 23 results
6. ISHIHARA Kyoko (30303944)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. GOTOW Takahiro (20135693)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. YAMADA Keiichi (70323334)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. BOCHIMOTO HIROKI (60632841)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
10. SATO Yoh-ichi (40118253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ONODERA Satoru (40137493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HABARA Yoshiaki (30142813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MIYATA Setsuya (30316351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SAINO Tomoyuki (40305991)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KAMETAKA Satoshi (10303950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Tobita Seiji (30164007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 似鳥徹 (90128934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 佐藤昇 (00254756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 春見達郎 (00261404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 甲賀大輔 (30467071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
21. TORII Seiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. 五味浩司

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

WATANABE TSUYOSHI 渡部 剛

WATANABE Tsuyoshi 渡部 剛

Research Projects

Research Products

Co-Researchers

Physiological significance of the granin protein family in the endocrine function, revealed by analyzing the phenotypes of newly established Sg2- and Sg3-deficient mice.Principal Investigator

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A novel experimental framework by using GnRH analogues to clarify the intracellular degradation processes of organelle outdated in their target cells/organs.Principal Investigator

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Diversity in the global organization of the Golgi apparatus in differentiated secretory cells.Principal Investigator

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Characteristics in the overall organization and dynamics of the Golgi apparatus in the anterior pituitary endocrine cells.Principal Investigator

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Effects of LHRH analogues on the ultrastructure of male rat pituitary gonadotropesPrincipal Investigator

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cDNA microarray analyses on the gene expression in the pituitary glands under the physiological and experimental conditions.Principal Investigator

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Analyses on the secretory granule formation by using a yeast two hybrid systemPrincipal Investigator

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WATANABE TSUYOSHI 渡部剛

WATANABE Tsuyoshi 渡部剛