• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Yoshihara Motojiro  吉原 基二郎

ORCIDConnect your ORCID iD *help
… Alternative Names

YOSHIHARA Motojiro  吉原 基二郎

Less
Researcher Number 80222397
Other IDs
Affiliation (Current) 2025: 国立研究開発法人情報通信研究機構, 未来ICT研究所神戸フロンティア研究センター, シニアマネージャー
Affiliation (based on the past Project Information) *help 2021 – 2025: 国立研究開発法人情報通信研究機構, 未来ICT研究所神戸フロンティア研究センター, 上席研究員
2021: 国立研究開発法人情報通信研究機構, 未来ICT研究所神戸フロンティア研究センター, 研究マネージャー
2020: 国立研究開発法人情報通信研究機構, 未来ICT研究所神戸フロンティアセンター, 上席研究員
2019 – 2020: 国立研究開発法人情報通信研究機構, 未来ICT研究所フロンティア創造総合研究室, 総括研究員
2015: 国立研究開発法人情報通信研究機構, 未来ICT研究所バイオICT研究室, 主任研究員 … More
2015: 国立研究開発法人情報通信研究機構, 未来ICT研究所・バイオICT研究室, 主任研究員
2014: 独立行政法人情報通信研究機構, 未来ICT研究所バイオICT研究室, 主任研究員
2000: 群馬大, 医学部, 助手
1993 – 2000: 群馬大学, 医学部, 助手
1996: 助手
1994: 群馬大学, 医学部・行動医学研究施設, 助手
1993: 群馬大学, 医学部・行動生理, 助手 Less
Review Section/Research Field
Principal Investigator
遺伝 / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / Biological Sciences / Genetics/Chromosome dynamics
Except Principal Investigator
神経・脳内生理学
Keywords
Principal Investigator
ショウジョウバエ / 神経筋接合部 / シナプス形成 / フィーディング・ニューロン / シナプス可塑性 / 記憶 / ローカルフィードバック仮説 / 遺伝解析 / 飛翔行動 / 標的認識 … More / 電気生理 / コマンドニューロン / シナプトブレビン / シナプス / 突然変異体 / エンハンサートラップ法 / 変態期 / 神経筋接合 / フィ-ディング・ニューロン / パブロフ条件反射 / 連合学習 / エングラム / 遺伝学 / 神経科学 / カルシウムイメージング / ライブイメージング / 条件反射 / NPプロジェクト / エンハンサー・トラップ / cAMP / シナプス電流 / シナプス伝達 / 成長錘 / エンバンサートラップ法 / 共焦点レーザー顕微鏡 / エンハンサートラップ … More
Except Principal Investigator
ショウジョウバエ / シナプス形成 / Drosophila / cAMP / 突然変異体 / グルタミン酸受容体 / rutabaga / dunce / reserve pool / endo cycling pool / exo / FM1-43 / mutants / シナプトブレビン / synaptic transmission / シナプス伝達 / 神経筋シナプス / シナプス小胞リサイクリング / グルタミン酸受容体分布 / ショウジョウバエ変異株 / シナプス電流 / 微小シナプス電流 / 受容体集積 / synaptic vesicle pools / metabotropic glutamate receptors / neuromuscular junctions / synaptobrevin / patch-clamp / パッチクランプ / PKA cascade / stimulation frequency / synaptic vesicles / cyclosporin A / forskolin / quantal content / cytochalasin D / high rate stimulation / low rate stimulation / synaptic vesicle / synaptic vesicle fusion / cyclic AMP / miniature synaptic currents / neuronal-synaptobrevin / SNARE hypothesis / リサイクリング / シナプス小胞 / shibire / 自発性微小シナプス電流 / 誘発性シナプス電流 / シナプス / csp / シナプス小胞融合 / 神経型シナプトブレビン / SNARE仮説 / Ca^<2+>imaging / Ca^<2+>influx / cysteine-string protein / synaptic vesicle iecycling / shibire mutant / presynaptic Ca^<2+>channel / Drosophila melanogaster / csp mutants / CSP変異株 / shibire変異株 / shibire変異種 / Ca channel / Ca流入 / Ca感受性色素 / csp変異株 / channel kinetics / ion permeation / receptor accumulation / glutamate receptor / genes / synapse formation / チャネルキネテイクス / イオン透過機序 / 受容体チャネル / 遺伝子 / 半致死株 / エンハンサートラップ / シナプス外型チャネル / シナプス型チャネル / シナプス前終末 / グルタミン酸受容体チャネル / シナプス増強 / 記憶・学習 / 代謝型グルタミン酸受容体 / Para変異株 / 神経活動依存性 / 温度感受性変異体 / 蛍光抗体染色 Less
  • Research Projects

    (20 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (11 People)
  •  “記憶の局所フィードバック仮説”-シナプス新生の記憶時リアルタイム追跡による検証Principal Investigator

    • Principal Investigator
      吉原 基二郎
    • Project Period (FY)
      2025 – 2029
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
    • Research Institution
      National Institute of Information and Communications Technology
  •  “記憶の局所フィードバック仮説” - 単一細胞上での短・長期記憶の追跡による検証Principal Investigator

    • Principal Investigator
      吉原 基二郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
    • Research Institution
      National Institute of Information and Communications Technology
  •  中枢単一同定ニューロンでのエングラム形成と消去のin vivoリアルタイム解析Principal Investigator

    • Principal Investigator
      吉原 基二郎
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute of Information and Communications Technology
  •  Testing the "local feedback hypothesis" as a basic mechanism of memory in the single identified neuronPrincipal Investigator

    • Principal Investigator
      Yoshihara Motojiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
    • Research Institution
      National Institute of Information and Communications Technology
  •  Genetic and physiological study of plasticity in neural circuit during Pavlovian conditioning.Principal Investigator

    • Principal Investigator
      Yoshihara Motojiro
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Genetics/Chromosome dynamics
    • Research Institution
      National Institute of Information and Communications Technology
  •  シナプス形成の遺伝解析Principal Investigator

    • Principal Investigator
      吉原 基二郎
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      遺伝
    • Research Institution
      Gunma University
  •  Analysis of Synaptic Transmission using Molecular Genetics

    • Principal Investigator
      KIDOKORO Yoshiaki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      神経・脳内生理学
    • Research Institution
      GUNMA UNIVERSITY SCHOOL OF MEDICINE
  •  シナプス伝達がシナプス形成に及ぼす影響

    • Principal Investigator
      城所 良明
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Gunma University
  •  Synaptic vesicle pools and vesicle recycling in nerve terminals

    • Principal Investigator
      KUROMI Hiroshi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      神経・脳内生理学
    • Research Institution
      Gunma University, School of Medicine, Institute for Behavioral Science
  •  シナプス形式の遺伝解析Principal Investigator

    • Principal Investigator
      吉原 基二郎
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      遺伝
    • Research Institution
      Gunma University
  •  Molecular Genetic Dissection of Synaptic Transmission

    • Principal Investigator
      KIDOKORO Yoshiaki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      神経・脳内生理学
    • Research Institution
      GUNMA UNIVERSITY SCHOOL OF MEDICINE
  •  シナプス形成の遺伝解析Principal Investigator

    • Principal Investigator
      吉原 基二郎
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      遺伝
    • Research Institution
      Gunma University
  •  Gene Control of Synaptic Transmission

    • Principal Investigator
      KIDOKORO Yoshiaki
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      神経・脳内生理学
    • Research Institution
      Gunma University
  •  シナプス形成に関与する遺伝子と可塑性

    • Principal Investigator
      城所 良明
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Gunma University
  •  ショウジョウバエ運動ニューロンによる標的認識の遺伝解析Principal Investigator

    • Principal Investigator
      吉原 基二郎
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      遺伝
    • Research Institution
      Gunma University
  •  ショウジョウバエ神経筋接合部をテデルとしたシナプス形成機構の遺伝学的解析Principal Investigator

    • Principal Investigator
      吉原 基二郎
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Gunma University
  •  ショウジョウバエ変態期における神経軸索の標的認認に関する分子遺伝学的研究Principal Investigator

    • Principal Investigator
      吉原 基二郎
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      遺伝
    • Research Institution
      Gunma University
  •  Nerve-muscle interaction during synapse formation and the role of genes

    • Principal Investigator
      KIDOKORO Yoshiaki
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      神経・脳内生理学
    • Research Institution
      GUNMA UNIVERSITY SCHOOL OF MEDICINE
  •  ショウジョバエ神経筋接合部をモデルとしたシナップス形成機構の遺伝学的解析Principal Investigator

    • Principal Investigator
      吉原 基二郎
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Gunma University
  •  キイロショウジョウバエ変態期における神経軸索の標的認識に関する分子遺伝学的研究Principal Investigator

    • Principal Investigator
      吉原 基二郎
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      遺伝
    • Research Institution
      Gunma University

All 2021 2020 2019 2016 2015

All Journal Article Presentation Patent

  • [Journal Article] Synaptotagmin 7 switches short-term synaptic plasticity from depression to facilitation by suppressing synaptic transmission2021

    • Author(s)
      Fujii Takaaki、Sakurai Akira、Littleton J. Troy、Yoshihara Motojiro
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 4059-4059

    • DOI

      10.1038/s41598-021-83397-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16275, KAKENHI-PROJECT-19H00998, KAKENHI-PUBLICLY-19H04767
  • [Journal Article] Alteration in information flow through a pair of feeding command neurons underlies a form of Pavlovian conditioning in the Drosophila brain2021

    • Author(s)
      Sakurai Akira、Littleton J. Troy、Kojima Hiroaki、Yoshihara Motojiro
    • Journal Title

      Current Biology

      Volume: 31 Issue: 18 Pages: 4163-4171

    • DOI

      10.1016/j.cub.2021.07.021

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16275, KAKENHI-PROJECT-19H00998
  • [Patent] 条件付けに用いる刺激の付与方法、試験の方法、方法を実施する装置、及び、脳灌流液2021

    • Inventor(s)
      櫻井晃、吉原基二郎
    • Industrial Property Rights Holder
      櫻井晃、吉原基二郎
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-171185
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-19H00998
  • [Patent] 先合いばさみ2020

    • Inventor(s)
      吉原基二郎
    • Industrial Property Rights Holder
      吉原基二郎
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-029436
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-19H00998
  • [Patent] 先合いばさみ2020

    • Inventor(s)
      吉原基二郎
    • Industrial Property Rights Holder
      吉原基二郎
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-029436
    • Filing Date
      2020
    • Data Source
      KAKENHI-PUBLICLY-19H04767
  • [Presentation] Synaptotagmin 7 switches short-term synaptic plasticity from depression to facilitation by suppressing synaptic transmission2020

    • Author(s)
      Takaaki Fujii, Akira Sakurai, J. Troy Littleton, Motojiro Yoshihara
    • Organizer
      新学術スクラップビルド班会議
    • Data Source
      KAKENHI-PUBLICLY-19H04767
  • [Presentation] Functional change of a feeding command neuron underlies Pavlovian conditioning in the Drosophila brain2020

    • Author(s)
      Motojiro Yoshihara.
    • Organizer
      新学術"スクラップ&ビルド"班会議
    • Data Source
      KAKENHI-PROJECT-19H00998
  • [Presentation] Functional change of a feeding command neuron underlies Pavlovian conditioning in the Drosophila brain2020

    • Author(s)
      Motojiro Yoshihara.
    • Organizer
      新学術スクラップビルド班会議
    • Data Source
      KAKENHI-PUBLICLY-19H04767
  • [Presentation] Synaptotagmin 7 suppresses synaptic transmission and is not the high affinity Ca2+ sensor for facilitation or asynchronous release at Drosophila embryonic NMJs2019

    • Author(s)
      Takaaki Fujii, Akira Sakurai, Akemi Kishi, J. Troy Littleton, and Motojiro Yoshihara
    • Organizer
      Cold Spring Harbor meeting, Neurobiology of Drosophila
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04767
  • [Presentation] Synaptotagmin 7 suppresses synaptic transmission and is not the high affinity Ca2+ sensor for facilitation or asynchronous release at Drosophila embryonic NMJs2019

    • Author(s)
      Takaaki Fujii, Akira Sakurai, Akemi Kishi, J. Troy Littleton, and Motojiro Yoshihara
    • Organizer
      Cold Spring Harbor Symposium, Neurobiology of Drosophila
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H00998
  • [Presentation] The Drosophila feeding circuit to connect synaptic plasticity to memory2019

    • Author(s)
      Motojiro Yoshihara.
    • Organizer
      新学術"スクラップ&ビルド"班会議
    • Data Source
      KAKENHI-PROJECT-19H00998
  • [Presentation] A neural correlate of Pavlovian conditioning in the Drosophila brain2019

    • Author(s)
      Akira Sakurai1,, J. Troy Littleton, Hiroaki Kojima, and Motojiro Yoshihara
    • Organizer
      Cold Spring Harbor Symposium, Neurobiology of Drosophila
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H00998
  • [Presentation] A neural correlate of Pavlovian conditioning in the Drosophila brain2019

    • Author(s)
      Akira Sakurai, J. Troy Littleton, Hiroaki Kojima, and Motojiro Yoshihara
    • Organizer
      Cold Spring Harbor meeting, Neurobiology of Drosophila
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04767
  • [Presentation] Feeding command neuron is a modification site in the Drosophila feeding neural circuit.2019

    • Author(s)
      Akira Sakurai, Hiroaki Kojima, Motojiro Yoshihara.
    • Organizer
      第42回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-19H00998
  • [Presentation] 脳が記憶をつくる"現場"をおさえる2016

    • Author(s)
      吉原基二郎
    • Organizer
      未来ICTシンポジウム
    • Place of Presentation
      東京ビッグサイト(東京都江東区)
    • Year and Date
      2016-01-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26891030
  • [Presentation] シナプス可塑性と記憶をつなぐ摂食コマンドニューロン-記憶のできる瞬 間を捉えるための新しいこころみ2015

    • Author(s)
      吉原基二郎
    • Organizer
      第1048回生物科学セミナー
    • Place of Presentation
      東京大学本郷2号館講堂(東京都文京区)
    • Year and Date
      2015-07-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-26891030
  • [Presentation] A neural correlate of Pavlovian conditioning in Drosophila brain2015

    • Author(s)
      Akira Sakurai, J. Troy Littleton, Hiroaki Kojima, and Motojiro Yoshihara
    • Organizer
      Cold Spring Harbor Symposium, Neurobiology of Drosophila
    • Place of Presentation
      Cold Spring Harbor Laboratory, New York, U.S.A.
    • Year and Date
      2015-09-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26891030
  • [Presentation] パブロフの条件反射に伴う摂食コマンドニューロンの可塑的変化2015

    • Author(s)
      櫻井晃、 J. Troy Littleton, 小嶋寛明、吉原基二郎
    • Organizer
      神経科学学会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-07-28
    • Data Source
      KAKENHI-PROJECT-26891030
  • 1.  KIDOKORO Yoshiaki (00053083)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  SAITOE Minoru (50261839)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  SAKURAI Akira (50749041)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 4.  KUROMI Hiroshi (30009633)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  SAKAI Takaomi (50322730)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  UMBACH JA
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  GUNDERSEN CB
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  GUNDERSEN Cameron.B
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  UMBACH Joy A.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  UMBACH Joy
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  GUNDERSEN Ca
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi