Toyama Kaoru 通山薫

… Alternative Names

TOHYAMA Kaoru 通山薫

通山薫トオヤマカオル

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Researcher Number	80227561
Other IDs
External Links
Affiliation (Current)	2025: 川崎医療福祉大学, 医療技術学部, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 川崎医療福祉大学, 医療技術学部, 教授 2008 – 2022: Kawasaki Medical School, 医学部, 教授 2003 – 2004: 川崎医科大学, 医学部, 教授 1994: 福井医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Laboratory medicine / Basic Section 52010:General internal medicine-related / Hematology Except Principal Investigator Basic Section 52010:General internal medicine-related / Medical and hospital managemen
Keywords	Principal Investigator 骨髄異形成症候群 / 遺伝子変異 / 白血病化 / 白血病移行 / シングルセル解析 / 造血障害 / 網羅的遺伝子解析 / 遺伝子 / 内科 / ゲノム … More / 網羅的ゲノム解析 / automated hematology analyzer / flow cytometry / minimal residual tumor cells / blast / acute myeloid leukemia / 自動検出法 / 白血病細胞 / 自動血球分析装置 / フローサイトメトリー / 微小残存腫瘍 / 芽球 / 急性骨髄性白血病 / 腫瘍関連遺伝子 / 好中球機能 / 食細胞機能 / 血球異形成 / 遺伝子ノックダウン法 / 細胞分化 / プロテオーム / マイクロアレイ / 血液学 / N-ras点突然変異 / 増殖因子依存性細胞株 / コロニー刺激因子 / CD34陽性細胞 … More Except Principal Investigator シグナル伝達 / 抗体療法 / daratumumab / CD38 / MPL / Calreticulin / チロシンキナーゼ / calreticulin / 骨髄増殖性腫瘍 / 知識データベース / SSMIX2 / データウエアハウス構築 / SS-MIX2 / FCS / スキャッターグラム / データウエアハウス / COVID-19 / MRSA感染症 / 自動血球計数装置 / 集団免疫 / 免疫応答 / データベース / スキャッタグラム / フローサイトメトリ / CBC Less

モデル細胞株のシングルセル解析による骨髄異形成症候群の急性白血病化機構の解明Principal Investigator
- Principal Investigator
  
  通山薫
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kawasaki University of Medical Welfare
抗CD38抗体による抗腫瘍効果の分子機構解明と新規併用療法の開発
- Principal Investigator
  
  北中明
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kawasaki Medical School
Strategy aiming at the inhibition of leukemic evolution of the myelodysplastic syndromes by the use of MDS-derived cell linesPrincipal Investigator
- Principal Investigator
  
  Tohyama Kaoru
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kawasaki Medical School
Elucidation of the molecular pathogenesis of myeloproliferative neoplasms with CALR mutations for the development of novel therapeutic strategies.
- Principal Investigator
  
  Kitanaka Akira
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kawasaki Medical School
Molecular mechanisms of leukemic transformation of myelodysplastic syndromes.Principal Investigator
- Principal Investigator
  
  TOHYAMA Kaoru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kawasaki Medical School
Elucidation of immune response pattern dynamics using automated hematology analyzer scattergram data.
- Principal Investigator
  
  Kataoka Hiromi
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical and hospital managemen
- Research Institution
  Kawasaki University of Medical Welfare
Search for the molecules involved in leukemic transformation of myelodysplastic syndromesPrincipal Investigator
- Principal Investigator
  
  TOHYAMA KAORU
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kawasaki Medical School
Approach to the molecular mechanisms of hematopoietic dysplasia aiming at elucidation of the pathogenesis of myelodysplastic syndromesPrincipal Investigator
- Principal Investigator
  
  TOHYAMA Kaoru
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kawasaki Medical School
Elucidation of the molecular mechanism leading to the dysplasia of blood cells in the myelodysplastic syndromesPrincipal Investigator
- Principal Investigator
  
  TOHYAMA Kaoru
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kawasaki Medical School
DEVELOPMENT OF A NEW DETECTION METHOD OF THE MINIMAL RESIDUAL TUMOR CELLSPrincipal Investigator
- Principal Investigator
  
  TOHYAMA Kaoru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  KAWASAKI MEDICAL SCHOOL
白血病・前白血病細胞の増殖機構と抗腫瘍剤およびサイトカインによるその制御の研究Principal Investigator
- Principal Investigator
  
  通山薫
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  福井医科大学

[Book] 血液専門医テキスト（改訂第4版）2023
- Author(s)
  日本血液学会（北中明, 通山薫 (担当:共著)）
- Total Pages
  668
- Publisher
  南江堂
- ISBN
  9784524203710
- Data Source
  KAKENHI-PROJECT-22K07488
[Book] 血液疾患最新の治療2020-20222019
- Author(s)
  北中　明, 通山　薫　部分執筆
- Total Pages
  390
- Publisher
  南江堂
- ISBN
  9784524249787
- Data Source
  KAKENHI-PROJECT-19K07880
[Book] 血液細胞アトラス　第6版2018
- Author(s)
  通山　薫、張替秀郎
- Total Pages
  418
- Publisher
  文光堂
- ISBN
  9784830614262
- Data Source
  KAKENHI-PROJECT-17K09026
[Book] 最新ガイドライン準拠　血液疾患　診断・治療方針2015
- Author(s)
  通山　薫
- Total Pages
  560
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-26460691
[Book] ブラッシュアップ骨髄不全症2015
- Author(s)
  通山　薫
- Total Pages
  193
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-26460691
[Book] スタンダード検査血液学　第3版2014
- Author(s)
  通山　薫
- Total Pages
  460
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-26460691
[Book] I.疾患編第3章血液・造血器疾患7.骨髄異形成症候群.わかりやすい内科学第3版2014
- Author(s)
  通山薫(井村裕夫総編集)
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-23590696
[Book] わかりやすい内科学第3版2014
- Author(s)
  通山　薫
- Total Pages
  992
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-23590696
[Book] 骨髄穿刺/骨髄生検.プリンシプル血液疾患の臨床・ここまできた白血病/MDS治療2013
- Author(s)
  通山薫(金倉譲総編集, 松村到専門編集)
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-23590696
[Book] プリンシプル血液疾患の臨床・ここまできた白血病/MDS治療2013
- Author(s)
  通山　薫
- Total Pages
  340
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-23590696
[Book] 腫瘍病理鑑別診断アトラス・造血器腫瘍2013
- Author(s)
  通山　薫
- Total Pages
  290
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-23590696
[Book] MDSにおけるリスク分類.腫瘍病理鑑別診断アトラス・造血器腫瘍2013
- Author(s)
  通山薫(定平吉都, 北川昌伸編集)
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-23590696
[Book] IV.血液像6.造血器腫瘍のWHO分類3.骨髄異形成症候群.顕微鏡検査ハンドブック―臨床に役立つ形態学2012
- Author(s)
  通山薫(菅野治重他編集)
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23590696
[Book] 顕微鏡検査ハンドブック―臨床に役立つ形態学2012
- Author(s)
  通山　薫
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23590696
[Book] 今日の治療指針2011
- Author(s)
  通山薫（分担執筆）
- Total Pages
  1978
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23590696
[Book] 骨髄異形成症候群D. MDSに対する新規治療薬.白血病・リンパ腫・骨髄腫―今日の診断と治療―第4版2011
- Author(s)
  松岡亮仁, 通山薫(木崎昌弘編著)
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23590696
[Book] 骨髄異形成症候群.今日の治療指針2011
- Author(s)
  通山薫(山口徹, 北原光夫, 福井次矢総編集)
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23590696
[Book] 血液専門医テキスト（日本血液学会　編集）2011
- Author(s)
  通山薫（分担執筆）
- Total Pages
  556
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-23590696
[Book] 主要な徴候と検査値異常2.貧血の鑑別.血液専門医テキスト2011
- Author(s)
  通山薫(日本血液学会編集)
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-23590696
[Book] 症候群ハンドブック2011
- Author(s)
  通山薫（分担執筆）
- Total Pages
  757
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-23590696
[Book] 5q-症候群.症候群ハンドブック2011
- Author(s)
  通山薫(井村裕夫総編集、福井次矢・辻省次編集)
- Total Pages
  336
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-23590696
[Book] 白血病・リンパ腫・骨髄腫―今日の診断と治療―第4版2011
- Author(s)
  松岡亮仁、通山薫
- Total Pages
  544
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23590696
[Book] WHO血液腫瘍分類～WHO分類2008をうまく活用するために～2010
- Author(s)
  通山薫(分担執筆)
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-20590591
[Book] WHO血液腫瘍分類～WHO分類2008をうまく活用するために～2010
- Author(s)
  通山薫
- Total Pages
  587
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-20590591
[Book] WHO分類第4版による白血病・リンパ系腫瘍の病態学2009
- Author(s)
  通山薫(分担執筆)
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20590591
[Journal Article] 骨髄系腫瘍概論/クローン性造血/骨髄系腫瘍を好発する遺伝性腫瘍症候群2023
- Author(s)
  北中明, 通山薫
- Journal Title
  
  臨床検査
  
  Volume: 67 Pages: 688-692
- Data Source
  KAKENHI-PROJECT-22K07488
[Journal Article] Integrated genetic and clinical prognostic factors for aggressive adult T-cell leukemia/lymphoma2023
- Author(s)
  Kameda Takuro、Kataoka Keisuke、Kamiunten Ayako、 et al
- Journal Title
  
  Haematologica
  
  Volume: - Issue: 8 Pages: 2178-2191
- DOI
  10.3324/haematol.2022.281510
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08479, KAKENHI-PROJECT-20K08715, KAKENHI-PROJECT-20H03514, KAKENHI-PROJECT-22K07488, KAKENHI-PROJECT-23K07840, KAKENHI-PROJECT-20K17403
[Journal Article] Histone deacetylase inhibitor, panobinostat, exerts anti-proliferative effect with partial normalization from aberrant epigenetic states on granulosa cell tumor cell lines.2022
- Author(s)
  Hazama Y, Tsujioka T, Kitanaka A, Tohyama K, Shimoya K.
- Journal Title
  
  PLoS One.
  
  Volume: 17(7) Issue: 7 Pages: 0271245-0271245
- DOI
  10.1371/journal.pone.0271245
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09505, KAKENHI-PROJECT-22K07488, KAKENHI-PROJECT-20H03582
[Journal Article] Prognosis of Indolent Adult T-Cell Leukemia/Lymphoma2022
- Author(s)
  Kameda T, Shide K, Tahira Y, Sekine M, Sato S, Ishizaki J, Takeuchi M, Akizuki K, Kamiunten A, Shimoda H, Toyama T, Maeda K, Yamashita K, Kawano N, Kawano H, Hidaka T, Yamaguchi H, Kubuki Y, Kitanaka A, Matsuoka H, Shimoda K
- Journal Title
  
  Viruses
  
  Volume: 14 Issue: 4 Pages: 710-710
- DOI
  10.3390/v14040710
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07880, KAKENHI-PROJECT-20K08715
[Journal Article] Preclinical characterisation and development of a novel myelodysplastic syndrome‐derived cell line2021
- Author(s)
  Shafiee Sahba、Gelebart Pascal、Popa Mihaela、Helles?y Monica、Hovland Randi、Brendsdal Forthun Rakel、Lee Jungwoo、Tohyama Kaoru、Molven Anders、Parekkadan Biju、Tore Gjertsen Bj?rn、Olsnes Kittang Astrid、McCormack Emmet
- Journal Title
  
  British Journal of Haematology
  
  Volume: 193 Issue: 2 Pages: 415-419
- DOI
  10.1111/bjh.17372
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03582
[Journal Article] VLX1570 induces apoptosis through the generation of ROS and induction of ER stress on leukemia cell lines2021
- Author(s)
  Kurozumi N, Tsujioka T, Ouchida M, Sakakibara K, Nakahara T, Suemori SI, Takeuchi M, Kitanaka A, Shibakura M, Tohyama K
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 8 Pages: 3302-3313
- DOI
  10.1111/cas.14982
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07880, KAKENHI-PROJECT-20H03582
[Journal Article] Higher average chemotherapy dose intensity improves prognosis in patients with aggressive adult T‐cell leukemia/lymphoma2020
- Author(s)
  Sekine M, Kameda T, Shide K, Maeda K, Toyama T, Kawano N, Takeuchi M, Kawano H, Sato S, Ishizaki J, Kukita T, Kamiunten A, Akizuki K, Tahira Y, Shimoda H, Hidaka T, Yamashita K, Matsuoka H, Kitanaka A, Kubuki Y, Shimoda K
- Journal Title
  
  European Journal of Haematology
  
  Volume: 106 Issue: 3 Pages: 398-407
- DOI
  10.1111/ejh.13565
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07880, KAKENHI-PROJECT-20K08715
[Journal Article] 細胞形態の特徴から診断し得た病初期の急性前骨髄球性白血病の1症例2020
- Author(s)
  小林美紀, 大倉貢, 向井祐子, 勝原祐香里, 安福明子, 通山薫, 北中明
- Journal Title
  
  日本検査血液学会雑誌
  
  Volume: 21 Pages: 207-213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07880
[Journal Article] Binimetinib, a novel MEK1/2 inhibitor, exerts anti-leukemic effects under inactive status of PI3Kinase/Akt pathway.2019
- Author(s)
  Sakakibara K, Tsujioka T, Kida JI, Kurozumi N, Nakahara T, Suemori SI, Kitanaka A, Arao Y, Tohyama K
- Journal Title
  
  International journal of hematology
  
  Volume: 110 Issue: 2 Pages: 213-227
- DOI
  10.1007/s12185-019-02667-1
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07880
[Journal Article] MDS細胞株とその亜株による研究応用2019
- Author(s)
  通山　薫
- Journal Title
  
  血液内科
  
  Volume: 78 Pages: 731-736
- NAID
  40021930439
- Data Source
  KAKENHI-PROJECT-17K09026
[Journal Article] Binimetinib, a novel MEK1/2 inhibitor, exerts anti-leukemic effects under inactive status of PI3Kinase/Akt pathway.2019
- Author(s)
  Sakakibara Kanae, Tsujioka Takayuki, Kida Jun-ichiro, Kurozumi Nami, Nakahara Takako, Suemori Shin-ichiro, Kitanaka Akira, Arao Yujiro, Tohyama Kaoru
- Journal Title
  
  Int J Hematol
  
  Volume: 110 Pages: 213-227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09026
[Journal Article] The augmented expression of the cytidine deaminase gene by 5-azacytidine predicts therapeutic efficacy in myelodysplastic syndromes2019
- Author(s)
  Murakami Yuichi、Kimura Yoshizo、Kawahara Akihiko、Mitsuyasu Shohei、Miyake Hidetoshi、Tohyama Kaoru、Endo Yoshio、Yoshida Nao、Imamura Yutaka、Watari Kosuke、Ono Mayumi、Okamura Takashi、Kuwano Michihiko
- Journal Title
  
  Oncotarget
  
  Volume: 10 Issue: 23 Pages: 2270-2281
- DOI
  10.18632/oncotarget.26784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09026
[Journal Article] Interobserver concordance of assessments of dysplasia and blast counts for the diagnosis of patients with cytopenia: From the Japanese central review study2018
- Author(s)
  Matsuda A, Kawabata H, Tohyama K, Maeda T, Araseki K, Hata T, Suzuki T, Kayano H, Shimbo K, Usuki K, Chiba S, Ishikawa T, Arima N, Nohgawa M, Ohta A, Miyazaki Y, Nakao S, Ozawa K, Arai S, Kurokawa M, Mitani K, Takaori-Kondo A
- Journal Title
  
  Leukemia Research
  
  Volume: 74 Pages: 137-143
- DOI
  10.1016/j.leukres.2018.06.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09026, KAKENHI-PROJECT-18K08371, KAKENHI-PROJECT-15K09489
[Journal Article] KIF20A, highly expressed in immature hematopoietic cells, supports the growth of HL60 cell line2018
- Author(s)
  Morita Hiroyuki、Matsuoka Akihito、Kida Jun-ichiro、Tabata Hiroyuki、Tohyama Kaoru、Tohyama Yumi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 108 Issue: 6 Pages: 607-614
- DOI
  10.1007/s12185-018-2527-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09026, KAKENHI-PROJECT-18K07432
[Journal Article] Present status and perspective of laboratory hematology in Japan: On the standardization of blood cell morphology including myelodysplasia: On behalf of the Japanese Society for Laboratory Hematology2018
- Author(s)
  Tohyama K.
- Journal Title
  
  International Journal of Laboratory Hematology
  
  Volume: 40 Issue: S1 Pages: 120-125
- DOI
  10.1111/ijlh.12819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09026
[Journal Article] An MDS-derived cell line and a series of its sublines serve as an in vitro model for the leukemic evolution of MDS2018
- Author(s)
  Kida Jun-ichiro、Tsujioka Takayuki、Suemori Shin-ichiro、Okamoto Shuichiro、Sakakibara Kanae、Takahata Takayuki、Yamauchi Takahiro、Kitanaka Akira、Tohyama Yumi、Tohyama Kaoru
- Journal Title
  
  Leukemia
  
  Volume: 32 Issue: 8 Pages: 1846-1850
- DOI
  10.1038/s41375-018-0189-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09026, KAKENHI-PROJECT-18K07294, KAKENHI-PROJECT-18K07432
[Journal Article] SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function2018
- Author(s)
  Sun J, He X, Zhu Y, Ding Z, Dong H, Feng Y, Du J, Wang H, Wu X, Zhang L, Yu X, Lin A, McDonald T, Zhao D, Wu H, Hua WK, Zhang B, Feng L, Tohyama K, Bhatia R, Oberdoerffer P, Chung YJ, Aplan PD, Boultwood J, Pellagatti A, Khaled S, Kortylewski M, Pichiorri F, Kuo YH, Carlesso N, Marcucci G, Jin H, Li L
- Journal Title
  
  Cell Stem Cell
  
  Volume: 23 Issue: 3 Pages: 355-369.e9
- DOI
  10.1016/j.stem.2018.07.018
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09026
[Journal Article] Validation of the revised International Prognostic Scoring System in patients with myelodysplastic syndrome in Japan: results from a prospective multicenter registry2017
- Author(s)
  Kawabata H, Tohyama K, Matsuda A, Araseki K, Hata T, Suzuki T, Kayano H, Shimbo K, Zaike Y, Usuki K, Chiba S, Ishikawa T, Arima N, Nogawa M, Ohta A, Miyazaki Y, Mitani K, Ozawa K, Arai S, Kurokawa M, Takaori-Kondo A
- Journal Title
  
  International Journal of Hematology
  
  Volume: 106 Issue: 3 Pages: 375-384
- DOI
  10.1007/s12185-017-2250-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09489, KAKENHI-PROJECT-16K09858, KAKENHI-PROJECT-17K09026
[Journal Article] A nationwide survey of hypoplastic myelodysplastic syndrome (a multicenter retrospective study)2017
- Author(s)
  Kobayashi T, Nannya Y, Ichikawa M, Oritani K, Kanakura Y, Tomita A, Kiyoi H, Kobune M, Kato J, Kawabata H, Shindo M, Torimoto Y, Yonemura Y, Tohyama K, et al
- Journal Title
  
  American Journal of Hematology
  
  Volume: 92 Issue: 12 Pages: 1324-1332
- DOI
  10.1002/ajh.24905
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09026, KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-17K09921, KAKENHI-PROJECT-17K09923, KAKENHI-PROJECT-15K09473, KAKENHI-PUBLICLY-16H01196, KAKENHI-PROJECT-15K09480
[Journal Article] Oxidative stress-induced JNK/AP-1 signaling is a major pathway involved in selective apoptosis of myelodysplastic syndrome cells by Withaferin-A2017
- Author(s)
  Oben KZ, Alhakeem SS, McKenna MK, Brandon JA, Mani R, Noothi SK, Jinpeng L, Akunuru S, Dhar SK, Singh IP, Liang Y, Wang C, Abdel-Latif A, Stills HF Jr, St Clair DK, Geiger H, Muthusamy N, Tohyama K, Gupta RC, Bondada S.
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 44 Pages: 77436-77452
- DOI
  10.18632/oncotarget.20497
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09026
[Journal Article] β-Catenin Is a Candidate Therapeutic Target for Myeloid Neoplasms with del(5q).2017
- Author(s)
  Li L, Sheng Y, Li W, Hu C, Mittal N, Tohyama K, Seba A, Zhao YY, Ozer H, Zhu T, Qian Z
- Journal Title
  
  Cancer Research
  
  Volume: 77 Issue: 15 Pages: 4116-4126
- DOI
  10.1158/0008-5472.can-17-0202
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09026
[Journal Article] Prognostic significance of Wilms tumor 1 mRNA expression levels in peripheral blood and bone marrow in patients with myelodysplastic syndromes.2016
- Author(s)
  Kobayashi S, Ueda Y, Nannya Y, Shibayama H, Tamura H, Ogata K, Akatsuka Y, Usuki K, Ito Y, Okada M, Suzuki T, Hata T, Matsuda A, Tohyama K, et al.
- Journal Title
  
  Cancer Biomarkers
  
  Volume: in press Issue: 1 Pages: 1-12
- DOI
  10.3233/cbm-160612
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460691, KAKENHI-PROJECT-15K09489
[Journal Article] Withaferin A suppresses the growth of myelodysplasia and leukemia cell lines by inhibiting cell cycle progression.2016
- Author(s)
  Okamoto S, Tsujioka T, Suemori SI, Kida JI, Kondo T, Tohyama Y, Tohyama K
- Journal Title
  
  Cancer Sci
  
  Volume: 107 Issue: 9 Pages: 1302-1314
- DOI
  10.1111/cas.12988
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460405, KAKENHI-PROJECT-26460691
[Journal Article] Five-aza-2'-deoxycytidine-induced hypomethylation of cholesterol 25-hydroxylase gene is responsible for cell death of myelodysplasia/leukemia cells.2015
- Author(s)
  Tsujioka T, Yokoi A, Itano Y, Takahashi K, Ouchida M, Okamoto S, Kondo T, Suemori S, Tohyama Y, Tohyama K
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 16709-16709
- DOI
  10.1038/srep16709
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460405, KAKENHI-PROJECT-26460691
[Journal Article] Rigosertib induces cell death of an MDS-derived cell line by DNA damage-induced G2/M arrest.2015
- Author(s)
  Hyoda T, Tsujioka T, Tohyama K, et al.
- Journal Title
  
  Cancer Science
  
  Volume: 106 Issue: 3 Pages: 287-293
- DOI
  10.1111/cas.12605
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460691
[Journal Article] An MDS xenograft model utilizing a patient-derived cell line.2014
- Author(s)
  Rhyasen GW, Kaoru Tohyama, et al.
- Journal Title
  
  Leukemia
  
  Volume: 未定 Issue: 5 Pages: 1142-1145
- DOI
  10.1038/leu.2013.372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] 〔特集臨床検査―ここまで進んだ検査の世界〕各論血液(赤血球と白血球)2014
- Author(s)
  通山薫
- Journal Title
  
  診断と治療
  
  Volume: 102 Pages: 93-99
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] Arsenic disulfide-triggered apoptosis and erythroid differentiation in myelodysplastic syndrome and acute myeloid leukemia cell lines.2014
- Author(s)
  Hu X-M, Tohyama K, et al.
- Journal Title
  
  Hematology
  
  Volume: 19 Issue: 6 Pages: 352-360
- DOI
  10.1179/1607845413y.0000000138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460691
[Journal Article] 〔特集造血器疾患―最新の治療戦略(赤血球系疾患)〕骨髄異形成症候群:最新の治療戦略2014
- Author(s)
  通山薫
- Journal Title
  
  臨床血液
  
  Volume: 55 Pages: 12-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] Delayed false elevation of circulating tacrolimus concentrations after cord blood transplantation in a patient with myelodysplastic syndrome.2014
- Author(s)
  Hayashi K, Tasaka T, Tohyama K, et al.
- Journal Title
  
  Internal Medicine
  
  Volume: 53 Pages: 2635-2638
- NAID
  130004713238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460691
[Journal Article] 〔特集　造血器疾患　―最新の治療戦略（赤血球系疾患）〕骨髄異形成症候群：最新の治療戦略．2014
- Author(s)
  通山　薫
- Journal Title
  
  臨床血液
  
  Volume: 55 Pages: 12-21
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] 骨髄異形成症候群の病態解明と診断の進歩．2014
- Author(s)
  通山　薫
- Journal Title
  
  最新医学
  
  Volume: 69 Pages: 2125-2133
- Data Source
  KAKENHI-PROJECT-26460691
[Journal Article] 〔特集　臨床検査―ここまで進んだ検査の世界〕各論　血液（赤血球と白血球）．2014
- Author(s)
  通山　薫
- Journal Title
  
  診断と治療
  
  Volume: 102 Pages: 93-99
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] Rab27a is essential for the formation of neutrophil extracellular traps (NETs) in neutrophil-like differentiated HL60 cells2014
- Author(s)
  Kawakami T, He J, Morita H, Yokoyama K, Kaji H, Tanaka C, Suemori S, Tohyama K, Tohyama Y
- Journal Title
  
  PLoS One
  
  Volume: 9(1) Issue: 1 Pages: e84704-e84704
- DOI
  10.1371/journal.pone.0084704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590374, KAKENHI-PROJECT-23590696
[Journal Article] Effects of DNA methyltransferase inhibitors (DNMTIs) on MDS-deribed cell lines.2013
- Author(s)
  Tsujioka T, Yokoi A, Kishimoto M, Kuyama A, Suemori S, Tohyama Y, Tohyama K
- Journal Title
  
  Exp Hematol
  
  Volume: 41 Issue: 2 Pages: 189-197
- DOI
  10.1016/j.exphem.2012.10.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590374, KAKENHI-PROJECT-23590696
[Journal Article] 〔特集白血病:診断と治療の進歩〕II.診断へのアプローチ1.FAB分類とWHO分類2013
- Author(s)
  通山薫
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 102 Pages: 1667-1675
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] 〔特集　白血病：診断と治療の進歩〕II.　診断へのアプローチ　１．FAB分類とWHO分類．2013
- Author(s)
  通山　薫
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 102 Pages: 1667-1675
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] Approach to new therapeutics : Investigation by the use of MDS-derived cell lines2012
- Author(s)
  Tsujioka T, Matsuoka A, Tohyama Y, Tohyama K
- Journal Title
  
  Curr Pharm Design
  
  Volume: 18 Pages: 3204-3214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] Rab27b regulates c-kit expression by controlling the secretion of stem cell factor.2012
- Author(s)
  Tanaka C
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 419 Issue: 2 Pages: 368-373
- DOI
  10.1016/j.bbrc.2012.02.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127, KAKENHI-PROJECT-23590374, KAKENHI-PROJECT-23590696
[Journal Article] Utility of DNA methyltransferase inhibitors for the treatment of myelodysplastic syndromes.2012
- Author(s)
  Kaoru Tohyama
- Journal Title
  
  Curr Pharm Design
  
  Volume: 18 Pages: 3190-3197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] Utility of DNA methyltransferase inhibitors for the treatment of myelodysplastic syndromes2012
- Author(s)
  Tohyama K
- Journal Title
  
  Curr Pharm Design
  
  Volume: 18 Pages: 3190-3197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] Morphologic analysis in myelodysplastic syndromes with del(5q) treated with lenalidomide. A Japanese multiinstitutional study2012
- Author(s)
  Matsuda A, Taniwaki M, Jinnai I, Harada H, Watanabe M, Suzuki K, Yanagita S, Suzuki T, Yoshida Y, Kimura A, Tsudo M, Tohyama K, Takatoku M, Ozawa K
- Journal Title
  
  Leuk Res
  
  Volume: (in press) Issue: 5 Pages: 575-580
- DOI
  10.1016/j.leukres.2011.11.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591206, KAKENHI-PROJECT-22591038, KAKENHI-PUBLICLY-23118518, KAKENHI-PROJECT-23590696, KAKENHI-PROJECT-23659493, KAKENHI-PROJECT-24591398
[Journal Article] 【難治性内科疾患の克服に向けて】特発性造血障害　特にMDS診療の展望2011
- Author(s)
  通山薫
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 100 Pages: 673-678
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] 骨髄異形成症候群診療の展望2011
- Author(s)
  通山薫
- Journal Title
  
  日本臨床
  
  Volume: 69 Pages: 2257-2266
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] MDSの過去、現在そして未来2011
- Author(s)
  通山薫
- Journal Title
  
  日本検査血液学会雑誌
  
  Volume: 12 Pages: 378-389
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] 5q- syndrome in Japan2011
- Author(s)
  Tasaka T, Tohyama K, Ohyashiki K, Ozawa K
- Journal Title
  
  Int J Hematol
  
  Volume: 93 Issue: 6 Pages: 827-829
- DOI
  10.1007/s12185-011-0868-x
- NAID
  10029535828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] 骨髄増殖性腫瘍におけるJAK2-V617F変異遺伝子比率と好中球アルカリホスファターゼスコアとの関連2011
- Author(s)
  奥野菜々子, 近藤敏範, 岸本光代, 辻岡貴之, 末盛晋一郎, 松岡亮仁, 久山亜紀, 田坂大象, 大倉貢, 野田幸代, 通山薫
- Journal Title
  
  日本検査血液学会雑誌
  
  Volume: 12 Pages: 170-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] MDSの新規治療2011
- Author(s)
  通山薫
- Journal Title
  
  臨床血液
  
  Volume: 52 Pages: 1535-1543
- NAID
  10029768845
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] Clinical utility of the neutrophil distribution pattern obtained using the CELL-DYN SAPPHIRE hematology analyzer for the diagnosis of myelodysplastic syndrome2011
- Author(s)
  Inaba T, Yuki Y, Yuasa S, Fujita N, Yoshitomi K, Kamisako T, Torii K, Okada T, Urasaki Y, Ueda T, Tohyama K
- Journal Title
  
  Int J Hematol
  
  Volume: 94 Issue: 2 Pages: 169-77
- DOI
  10.1007/s12185-011-0892-x
- NAID
  10029537093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] 第12回日本検査血液学会学術集会会長講演:MDSの過去、現在そして未来2011
- Author(s)
  通山薫
- Journal Title
  
  日本検査血液学会雑誌
  
  Volume: 12 Pages: 378-389
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] 第38回内科学の展望「難治性内科疾患の克服に向けて」8.特発性造血障害―特にMDS診療の展望2011
- Author(s)
  通山薫
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 100 Pages: 673-678
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] レナリドミドによる5q-MDS細胞の細胞分裂阻害2011
- Author(s)
  松岡亮仁, 通山薫
- Journal Title
  
  血液内科
  
  Volume: 62 Pages: 208-214
- NAID
  40019064661
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] Genome-wide identification of human microRNAs located in leukemia-associated genomic alterations2011
- Author(s)
  Starczynowski DT, Morin R, McPherson A, Lam J, Chari R, Wegrzyn J, Kuchenbauer F, Hirst M, Tohyama K, Humphries RK, Lam WL, Marra M, Karsan A
- Journal Title
  
  Blood
  
  Volume: 117 Issue: 2 Pages: 595-607
- DOI
  10.1182/blood-2010-03-277012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] 綜説シリーズ―現代医学の焦点「骨髄異形成症候群診療の展望」2011
- Author(s)
  通山薫
- Journal Title
  
  日本臨床
  
  Volume: 69 Pages: 2257-2266
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] Multicenter phase II trial of vitamin K_2 monotherapy and vitamin K_2 plus 1α-hydroxyvitamin D_3 combination therapy for low-risk myelodysplastic syndromes.2010
- Author(s)
  Akiyama N, Miyazawa K, Kanda Y, Tohyama K, Omine M, Mitani K, Ohyashiki K
- Journal Title
  
  Leukemia Research 34
  
  Pages: 1151-1157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590591
[Journal Article] Prognostic significance of WT1 mRNA and anti-WT1 antibody levels in peripheral blood in patients with myelodysplastic syndromes.2010
- Author(s)
  Tamura H, Dan K, Yokose N, Iwakiri R, Ohta M, Sakamaki H, Tohyama K, Kondo A, Hyodo H, Nakamura K, Yamashita T, Elisseeva OA, Oka Y, Oji Y, Sugiyama H, Ogata K
- Journal Title
  
  Leukemia Research 34
  
  Pages: 986-990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590591
[Journal Article] Lenalidomide induces cell death in an MDS-derived cell line with deletion of chromosome 5q by inhibition of cytokinesis.2010
- Author(s)
  Matsuoka A, Tochigi A, Kishimoto M, Nakahara T, Kondo T, Tsujioka T, Tasaka T, Tohyama Y, Tohyama K
- Journal Title
  
  Leukemia 24
  
  Pages: 748-755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590591
[Journal Article] Lenalidomide is active in Japanese patients with symptomatic anemia in low- or intermediate-1 risk myelodysplastic syndromes (MDS) with a deletion 5q abnormality.2009
- Author(s)
  Harada H, Watanabe M, Suzuki K, Yanagita S, Suzuki T, Yoshida Y, Kimura A, Tsudo M, Matsuda A, Tohyama K, Taniwaki M, Takeshita K, Takatoku M, Ozawa K
- Journal Title
  
  International Journal of Hematology 90
  
  Pages: 353-360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590591
[Journal Article] MDS診療の最近の進歩「5q-症候群の責任遺伝子とレナリドマイドの分子作用機序」2009
- Author(s)
  松岡亮仁、通山薫
- Journal Title
  
  血液・腫瘍科 59
  
  Pages: 33-39
- Data Source
  KAKENHI-PROJECT-20590591
[Journal Article] MDS診療の最近の進歩「5q-症候群の責任遺伝子とレナリドマイドの分子作用機序」2009
- Author(s)
  松岡亮仁, 通山薫
- Journal Title
  
  血液・腫瘍科 59
  
  Pages: 33-39
- Data Source
  KAKENHI-PROJECT-20590591
[Journal Article] High-resolution whole genome tiling path array CGH analysis of CD34^+ cells from patients with low-risk myelodysplastic syndromes reveals cryptic copy number alterations and predicts overall and leukemia-free survival.2008
- Author(s)
  Starczynowski DT, Vercauteren S, Telenius A, Sung S, Tohyama K, Brooks-Wilson A, Spinelli JJ, Eaves CJ, Eaves AC, Horsman DE, Lam WL, Karsan A
- Journal Title
  
  Blood 112
  
  Pages: 3412-3424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590591
[Journal Article] Myelodysplastic syndrome (MDS) with chromosome 5 abnormalities : a nation-wide survey in Japan.2008
- Author(s)
  Tasaka T, Tohyama K, Kishimoto M, Ohyashiki K, Mitani K, Hotta T, Kanamaru A, Okamoto S, Karasawa M, Kimura A, Tomonaga M, Uchiyama T, Ozawa K
- Journal Title
  
  Leukemia 22
  
  Pages: 1874-1881
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590591
[Journal Article] Improved Detection of Minimal Acute Myeloid Leukemia Cells by he Use of the Combined Parameters of XE-2100^<TM> Hematology Analyzer
- Author(s)
  Kaoru Tohyama, et al.
- Journal Title
  
  Cytometry (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590502
[Journal Article] Improved Detection of Minimal Acute Myeloid Leukemia Cells by the Use of the Combined Parameters of XE-2100^<TM> Hematology Analyzer
- Author(s)
  Kaoru Tohyama, 他8名
- Journal Title
  
  Cytometry (in press)
- Data Source
  KAKENHI-PROJECT-15590502
[Journal Article] Improved Detection of Minimal Acute Myeloid Leukemia Cells by the Use of the Combined Parameters of XE-2100^<TM> Hematology Analyzer
- Author(s)
  Kaoru Tohyama 他8名
- Journal Title
  
  Cytometry (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590502
[Presentation] 骨髄増殖性腫瘍の早期診断を目的とした好塩基球増加症スクリーニング体制の検討2023
- Author(s)
  近藤敏範, 今田昌秀, 内田圭一, 山本絵梨, 富岡菜々子, 小川千紘, 大倉尚子, 北中明, 通山薫, 近藤英生, 和田秀穂
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07488
[Presentation] 赤芽球系異形成が及ぼす再生不良性貧血の予後への影響2022
- Author(s)
  高折晃史, 通山薫, 北中明, 黒川峰夫, 三谷絹子（他12名、9番目）
- Organizer
  厚生労働科学研究費補助金「特発性造血障害に関する調査研究」令和4年度第1回班会議総会
- Data Source
  KAKENHI-PROJECT-22K07488
[Presentation] ヒト白血病細胞株における新規MEK1/2阻害剤ビニメチニブの効果2019
- Author(s)
  榊原佳奈枝, 辻岡貴之, 木田潤一郎, 中原貴子, 末盛晋一郎, 北中　明, 荒尾雄二郎, 通山　薫
- Organizer
  第66回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07880
[Presentation] 骨髄異形成症候群（MDS）の形態診断---WHO分類2017年版を踏まえて2019
- Author(s)
  通山　薫
- Organizer
  第58回日本血液学会中国四国地方会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09026
[Presentation] 血液形態診断のためのケースカンファレンス　前立腺癌治療中の好中球減少2019
- Author(s)
  小林美紀, 大倉　貢, 向井祐子, 勝原祐香里, 安福明子, 北中　明, 通山　薫
- Organizer
  第66回日本臨床検査医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07880
[Presentation] Srcチロシンキナーゼ抑制によるCALR変異を有する骨髄増殖性腫瘍の増殖抑制2019
- Author(s)
  木田潤一郎, 榊原佳奈枝, 辻岡貴之, 末盛晋一郎, 下田和哉, 通山　薫, 北中　明
- Organizer
  第66回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07880
[Presentation] MDSの形態診断～～異形成との遭遇2019
- Author(s)
  通山　薫
- Organizer
  第10回日本血液学会関東甲信越地方会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09026
[Presentation] 臨床検査からのメッセージ～～さまざまなご縁とともに2019
- Author(s)
  通山　薫
- Organizer
  第66回日本臨床検査医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09026
[Presentation] Challenges in laboratory hematology in different regions of the world: Perspectives from Japan.2018
- Author(s)
  Kaoru Tohyama
- Organizer
  ISLH 2018 in Brussels
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09026
[Presentation] 骨髄異形成症候群（MDS）の形態診断---WHO分類2017年版をふまえて2018
- Author(s)
  通山　薫
- Organizer
  第9回日本血液学会関東甲信越地方会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09026
[Presentation] 骨髄異形成症候群（MDS）の形態診断---WHO分類2017年版を踏まえて2018
- Author(s)
  通山　薫
- Organizer
  第58回日本血液学会中国四国地方会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09026
[Presentation] 蛍光顕微鏡を用いた巨核球中DNA量の解析2017
- Author(s)
  中原貴子, 末盛晋一郎, 辻岡貴之, 片岡浩巳, 柴倉美砂子, 通山薫
- Organizer
  第64回日本臨床検査医学会総会
- Data Source
  KAKENHI-PROJECT-17K09253
[Presentation] 骨髄系腫瘍へのアプローチ---形態学の視点から2016
- Author(s)
  通山　薫
- Organizer
  第14回日本検査血液学会北海道支部総会
- Place of Presentation
  札幌市（北海道大学医学部）
- Year and Date
  2016-06-11
- Invited
- Data Source
  KAKENHI-PROJECT-26460691
[Presentation] みんなで取り組もう、MDSの異形成判定2016
- Author(s)
  通山　薫
- Organizer
  日本検査血液学会　第14回冬季セミナー
- Place of Presentation
  パレス松洲（宮城）
- Year and Date
  2016-02-27
- Invited
- Data Source
  KAKENHI-PROJECT-26460691
[Presentation] 血球形態から分かる骨髄系腫瘍の病態2015
- Author(s)
  通山　薫
- Organizer
  第19回ILYH(Interactive Lectures for Young Hematologist)研究会
- Place of Presentation
  野村コンファレンスセンター新宿（東京）
- Year and Date
  2015-06-12
- Invited
- Data Source
  KAKENHI-PROJECT-26460691
[Presentation] 血液検査技師が知っておくべきMDS---血球の異形成の捉え方、考え方2015
- Author(s)
  通山　薫
- Organizer
  日本検査血液学会　第13回冬季セミナー
- Place of Presentation
  クロスウェーブ幕張（千葉）
- Year and Date
  2015-02-14
- Invited
- Data Source
  KAKENHI-PROJECT-26460691
[Presentation] 小酒井望賞受賞講演「『白血病細胞の分化過程の解析と分化誘導の評価診断に関する研究』およびその後の進展―血液形態学から骨髄異形成症候群へのアプローチ」2014
- Author(s)
  通山薫
- Organizer
  平成25年度公益信託臨床検査医学研究振興基金授賞式
- Place of Presentation
  東京都(東京ジョンブル)
- Year and Date
  2014-02-07
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 形態異常からわかる病態2014
- Author(s)
  通山　薫
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場（大阪）
- Year and Date
  2014-10-31
- Invited
- Data Source
  KAKENHI-PROJECT-26460691
[Presentation] MDSの診断と治療2014
- Author(s)
  通山薫
- Organizer
  日本血液学会中四国地方会・教育セミナー
- Place of Presentation
  徳島市(ザ・グランドパレス徳島)
- Year and Date
  2014-02-28
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 「造血器腫瘍の先端医療を支える臨床検査」：診断確定・病型分類のための血液検査・形態診断～骨髄異形成症候群．2014
- Author(s)
  通山　薫
- Organizer
  第61回日本臨床検査医学会学術集会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2014-11-25
- Invited
- Data Source
  KAKENHI-PROJECT-26460691
[Presentation] MDS 診断への道しるべ　---　形態とどのように付き合うか？2014
- Author(s)
  通山　薫
- Organizer
  平成26年度日本臨床衛生検査技師会　中部圏支部臨床血液部門研修会
- Place of Presentation
  岐阜大学医学部（岐阜）
- Year and Date
  2014-12-14
- Invited
- Data Source
  KAKENHI-PROJECT-26460691
[Presentation] 特別講演「MDSの形態診断～異形成をどのように捉えるか」2014
- Author(s)
  通山薫
- Organizer
  第9回Kyoto Hematology Forum
- Place of Presentation
  京都市(ウェスティン都ホテル京都)
- Year and Date
  2014-02-01
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 講演「骨髄異形成症候群(MDS)の形態的特徴から診断まで」2013
- Author(s)
  通山薫
- Organizer
  静岡県臨床衛生検査技師会第14回静岡血液フォーラム
- Place of Presentation
  静岡市(市立静岡病院)
- Year and Date
  2013-12-15
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 教育講演「骨髄異形成症候群の形態診断---骨髄判定を担うあなたのために」2013
- Author(s)
  通山薫
- Organizer
  第19回関甲信支部・首都圏支部合同血液検査研修会
- Place of Presentation
  栃木県(獨協医科大学)
- Year and Date
  2013-09-29
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 教育講演「骨髄異形成症候群の形態診断」2013
- Author(s)
  通山薫
- Organizer
  第11回骨髄病理研究会
- Place of Presentation
  倉敷市(川崎医科大学)
- Year and Date
  2013-09-01
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 特別講演「骨髄異形成症候群の形態学的診断」2013
- Author(s)
  通山薫
- Organizer
  東京血液レジデント勉強会
- Place of Presentation
  東京都(コートヤード・マリオット銀座東武ホテル)
- Year and Date
  2013-04-26
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 講演「血球形態学への誘い(いざない)～そして骨髄像のプロフェッショナルへ～」2013
- Author(s)
  通山薫
- Organizer
  神奈川県臨床検査技師会血液研究班平成25年度研修会
- Place of Presentation
  横浜市(かながわ労働プラザ)
- Year and Date
  2013-07-13
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 特別講演「MDSの形態診断」2013
- Author(s)
  通山薫
- Organizer
  第12回自治医大クリニカルヘマトロジーセミナー
- Place of Presentation
  栃木県下野市(自治医科大学)
- Year and Date
  2013-11-22
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 特別講演「MDSの形態診断-特に特徴的な形態異常を的確に捉えることを目的に-」2013
- Author(s)
  通山薫
- Organizer
  日本検査血液学会静岡支部サーベイ報告会
- Place of Presentation
  静岡市(静岡赤十字病院)
- Year and Date
  2013-10-26
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 特別講演「MDSの形態診断」2013
- Author(s)
  通山薫
- Organizer
  第3回神奈川MDS研究会
- Place of Presentation
  横浜市(ホテルキャメロットジャパン)
- Year and Date
  2013-01-25
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] パネルディスカッション―血液の機能を探る「赤血球―全身への酸素の運搬役―」2012
- Author(s)
  通山薫
- Organizer
  第32回メディコピア教育講演シンポジウム
- Place of Presentation
  東京都(東京国際フォーラム)
- Year and Date
  2012-01-08
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 教育講演「骨髄不全症候群:再生不良性貧血とMDSの鑑別―内科の立場から―」2012
- Author(s)
  通山薫
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都市(国立京都国際会館)
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 特別講演「MDS診療の展望」2012
- Author(s)
  通山薫
- Organizer
  第2回MDS・分子標的療法研究会
- Place of Presentation
  東京都(フォーシーズンズホテル)
- Year and Date
  2012-06-29
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 特別講演「MDS---この難解な疾患の克服に向けて」2012
- Author(s)
  通山薫
- Organizer
  第22回群馬血液疾患研究会
- Place of Presentation
  前橋市(ロイヤルチェスター前橋)
- Year and Date
  2012-11-16
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 講演「MDSの最新情報」2012
- Author(s)
  通山薫
- Organizer
  第3回香川血液疾患フォーラム
- Place of Presentation
  高松市(JRホテルクレメント高松)
- Year and Date
  2012-10-26
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 血液の機能を探る「赤血球―全身への酸素の運搬役―」2012
- Author(s)
  通山薫
- Organizer
  第32回メディコピア教育講演シンポジウム(招待講演)
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 教育講演「骨髄異形成症候群―MDSの新規治療」2011
- Author(s)
  通山薫
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋市(名古屋国際会議場)
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 蛍光顕微鏡を用いた新たなDNA量解析法の試み　巨核球中のDNA ploidyの解析2011
- Author(s)
  大石徹, 中原貴子, 山本博美, 通山薫
- Organizer
  第12回日本検査血液学会学術集会
- Place of Presentation
  倉敷市
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] MDS－最近の話題2011
- Author(s)
  通山薫
- Organizer
  第12回東海難治性血液腫瘍研究会(招待講演)
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 蛍光顕微鏡を用いた新たなDNA量解析法の試み―巨核球中のDNA ploidyの解析2011
- Author(s)
  大石徹, 中原貴子, 山本博美, 通山薫
- Organizer
  第12回日本検査血液学会学術集会
- Place of Presentation
  倉敷市(川崎医療福祉大学)
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 骨髄異形成症候群―MDSの新規治療2011
- Author(s)
  通山薫
- Organizer
  第73回日本血液学会学術集会(招待講演)
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 教育講演「MDS---どのように診断し、どのように治療するか」2011
- Author(s)
  通山薫
- Organizer
  第29回日本血液学会北陸地方会
- Place of Presentation
  金沢市(石川県立中央病院健康教育館)
- Year and Date
  2011-07-23
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] MDS---どのように診断し、どのように治療するか2011
- Author(s)
  通山薫
- Organizer
  第29回日本血液学会北陸地方会(招待講演)
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] MDS－診断と治療の展望―2011
- Author(s)
  通山薫
- Organizer
  第22回臨床血液セミナー(招待講演)
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 特別講演「MDS-診断と治療の展望―」2011
- Author(s)
  通山薫
- Organizer
  第22回臨床血液セミナー
- Place of Presentation
  大阪市(北野病院)
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 大会長講演「MDSの過去、現在そして未来」2011
- Author(s)
  通山薫
- Organizer
  第12回日本検査血液学会
- Place of Presentation
  倉敷市(川崎医療福祉大学)
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] MDSの過去、現在そして未来2011
- Author(s)
  通山薫
- Organizer
  第12回日本検査血液学会学術集会(招待講演)
- Place of Presentation
  倉敷市
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 特別講演「MDS-最近の話題」2011
- Author(s)
  通山薫
- Organizer
  第12回東海難治性血液腫瘍研究会
- Place of Presentation
  名古屋市(名古屋東急ホテル)
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 難治性内科疾患の克服に向けて 8.特発性造血障害、特にMDSの診療と展望2010
- Author(s)
  通山薫
- Organizer
  日本内科学会学術集会第38回内科学の展望
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2010-12-05
- Data Source
  KAKENHI-PROJECT-20590591
[Presentation] 難治性内科疾患の克服に向けて 8.特発性造血障害、特にMDSの診療と展望2010
- Author(s)
  通山薫
- Organizer
  日本内科学会学術集会第38回内科学の展望
- Place of Presentation
  国立京都国際会館
- Year and Date
  2010-12-05
- Data Source
  KAKENHI-PROJECT-20590591
[Presentation] 骨髄異形成症候群のWHO-2008分類2009
- Author(s)
  通山薫
- Organizer
  第58回日本医学検査学会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2009-08-01
- Data Source
  KAKENHI-PROJECT-20590591
[Presentation] 骨髄異形成症候群のWHO-2008分類2009
- Author(s)
  通山薫
- Organizer
  日本医学検査学会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2009-08-01
- Data Source
  KAKENHI-PROJECT-20590591
[Presentation] 骨髄異形成症候群由来細胞株MDS-Lに対するlenalidomideの影響2008
- Author(s)
  松岡亮仁、近藤敏範、辻岡貴之、中原貴子、栃木亜紀、田坂大象、通山薫
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-20590591
[Presentation] 骨髄異形成症候群の形態診断
- Author(s)
  通山　薫
- Organizer
  第11回骨髄病理研究会
- Place of Presentation
  川崎医科大学（倉敷）
- Invited
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 骨髄不全症候群：再生不良性貧血とMDSの鑑別―内科の立場から―
- Author(s)
  通山　薫
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  国立京都国際会館（京都）
- Invited
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] MDS診療の展望
- Author(s)
  通山　薫
- Organizer
  第2回MDS・分子標的療法研究会
- Place of Presentation
  フォーシーズンズホテル（東京）
- Invited
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] MDS---この難解な疾患の克服に向けて
- Author(s)
  通山　薫
- Organizer
  第22回群馬血液疾患研究会
- Place of Presentation
  ロイヤルチェスター前橋（前橋）
- Invited
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 骨髄異形成症候群の形態診断---骨髄判定を担うあなたのために
- Author(s)
  通山　薫
- Organizer
  第19回関甲信支部・首都圏支部合同血液検査研修会
- Place of Presentation
  獨協医科大学（栃木）
- Invited
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] MDSの形態診断～異形成をどのように捉えるか
- Author(s)
  通山　薫
- Organizer
  第9回Kyoto Hematology Forum
- Place of Presentation
  ウェスティン都ホテル京都（京都）
- Invited
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] MDSの形態診断－特に特徴的な形態異常を的確に捉えることを目的に－
- Author(s)
  通山　薫
- Organizer
  日本検査血液学会静岡支部　サーベイ報告会
- Place of Presentation
  静岡赤十字病院（静岡）
- Invited
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 骨髄異形成症候群（MDS）の形態的特徴から診断まで
- Author(s)
  通山　薫
- Organizer
  静岡県臨床衛生検査技師会第14回静岡血液フォーラム
- Place of Presentation
  市立静岡病院（静岡）
- Invited
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] MDSの形態診断
- Author(s)
  通山　薫
- Organizer
  第3回神奈川MDS研究会
- Place of Presentation
  ホテルキャメロットジャパン（横浜）
- Invited
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] MDSの診断と治療
- Author(s)
  通山　薫
- Organizer
  日本血液学会中四国地方会・教育セミナー
- Place of Presentation
  ザ・グランドパレス徳島（徳島）
- Invited
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 『白血病細胞の分化過程の解析と分化誘導の評価診断に関する研究』およびその後の進展 ― 血液形態学から骨髄異形成症候群へのアプローチ
- Author(s)
  通山　薫
- Organizer
  平成25年度　公益信託　臨床検査医学研究振興基金授賞式
- Place of Presentation
  東京ジョンブル（東京）
- Invited
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] MDSの形態診断
- Author(s)
  通山　薫
- Organizer
  第12回自治医大クリニカルヘマトロジーセミナー
- Place of Presentation
  自治医科大学（栃木）
- Invited
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 血球形態学への誘い（いざない）～そして骨髄像のプロフェッショナルへ～
- Author(s)
  通山　薫
- Organizer
  神奈川県臨床検査技師会血液研究班平成25年度研修会
- Place of Presentation
  かながわ労働プラザ（横浜）
- Invited
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] 骨髄異形成症候群の形態学的診断
- Author(s)
  通山　薫
- Organizer
  東京血液レジデント勉強会
- Place of Presentation
  コートヤード・マリオット銀座東武ホテル（東京）
- Invited
- Data Source
  KAKENHI-PROJECT-23590696
[Presentation] MDSの最新情報
- Author(s)
  通山　薫
- Organizer
  第3回香川血液疾患フォーラム
- Place of Presentation
  JRホテルクレメント高松（高松）
- Invited
- Data Source
  KAKENHI-PROJECT-23590696

1. TSUJIOKA Takayuki (50330551)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
2. TASAKA Taizo (80343309)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. SUEMORI Shin-ichiro (60330552)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. Kataoka Hiromi (80398049)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. Kitanaka Akira (70343308)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
6. 通山由美 (70362770)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. ITOH Mitsuru (00360272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 三上史哲 (80550392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 松村敬久 (10274391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 久原太助 (80457407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TANAKA Chisato

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. MORITA Hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. HARADA Yuka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 鈴木隆浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 下屋浩一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 加地弘明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 原田浩徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Toyama Kaoru 通山 薫

TOHYAMA Kaoru 通山 薫

通山 薫 トオヤマ カオル

Research Projects

Research Products

Co-Researchers

モデル細胞株のシングルセル解析による骨髄異形成症候群の急性白血病化機構の解明Principal Investigator

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抗CD38抗体による抗腫瘍効果の分子機構解明と新規併用療法の開発

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Strategy aiming at the inhibition of leukemic evolution of the myelodysplastic syndromes by the use of MDS-derived cell linesPrincipal Investigator

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Elucidation of the molecular pathogenesis of myeloproliferative neoplasms with CALR mutations for the development of novel therapeutic strategies.

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Molecular mechanisms of leukemic transformation of myelodysplastic syndromes.Principal Investigator

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Elucidation of immune response pattern dynamics using automated hematology analyzer scattergram data.

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Search for the molecules involved in leukemic transformation of myelodysplastic syndromesPrincipal Investigator

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Approach to the molecular mechanisms of hematopoietic dysplasia aiming at elucidation of the pathogenesis of myelodysplastic syndromesPrincipal Investigator

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Elucidation of the molecular mechanism leading to the dysplasia of blood cells in the myelodysplastic syndromesPrincipal Investigator

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DEVELOPMENT OF A NEW DETECTION METHOD OF THE MINIMAL RESIDUAL TUMOR CELLSPrincipal Investigator

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白血病・前白血病細胞の増殖機構と抗腫瘍剤およびサイトカインによるその制御の研究Principal Investigator

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[Book] 血液専門医テキスト（改訂第4版）2023

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[Book] 血液疾患最新の治療2020-20222019

Author(s)

Toyama Kaoru 通山薫

TOHYAMA Kaoru 通山薫

通山薫トオヤマカオル

[Book] 血液細胞アトラス　第6版2018

[Book] 最新ガイドライン準拠　血液疾患　診断・治療方針2015

[Book] スタンダード検査血液学　第3版2014