MUKAMOTO MASAFUMI 向本雅郁

… Alternative Names

MUKAMOTO Masafumi 向本雅郁

MUKAMOTO Masaya 向本雅郁

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Researcher Number	80231629
Other IDs
External Links
Affiliation (Current)	2025: 大阪公立大学, 大学院獣医学研究科 , 客員研究員
Affiliation (based on the past Project Information) *help	2023: 大阪公立大学, 大学院獣医学研究科, 客員研究員 2022: 大阪公立大学, 大学院獣医学研究科, 教授 2016 – 2021: 大阪府立大学, 生命環境科学研究科, 教授 2014: 大阪府立大学, 生命環境科学研究科, 教授 2013 – 2014: 大阪府立大学, 生命環境科学研究科(系), 教授 … More 2012: 大阪府立大学, 生命環境科学研究科(系), 准教授 2007 – 2011: Osaka Prefecture University, Graduate School of Life and Environmental Science, Associate Professor 2005 – 2006: Osaka Prefecture University, Graduate School of Life and Environmental Science, Associate Professor, 生命環境科学研究科, 助教授 2004: 大阪府立大学, 農学生命科学研究科, 助教授 2000: Graduate School of Agriculture and Biological Science, Osaka Prefecture University Assistant Professor, 農学生命科学研究科, 講師 1998 – 1999: 大阪府立大学, 農学部, 助手 Less
Review Section/Research Field	Principal Investigator Applied veterinary science / Basic Section 42020:Veterinary medical science-related / Veterinary medical science Except Principal Investigator Basic veterinary science/Basic zootechnical science / Laboratory animal science / Applied veterinary science
Keywords	Principal Investigator NetB / ウエルシュ菌 / septicum / 心不全 / 心臓 / 小腸上皮細胞 / 壊死性腸炎 / 毒素 / LMH / 受容体 … More / 鶏壊死性腸炎 / Clostridium / ニワトリ / 腸炎 / 細胞壊死毒素 / クロストリジウム / 鶏 / siRNA / ウェルシュ菌 / 二成分制御系 / 非定型β２毒素 / α毒素 / 炎症反応 / 腸管上皮細胞 / サイトカイン / 家きん / 病原因子 / 孔形成毒素 / heart failure / actin / GPI-anchored protein / raft / cholesterol / cytolethal toxin / 細胞傷害 / アクチン / GPIアンカー蛋白 / ラフト / コレステロール / 壊死毒 / 感染症 / 細菌毒素 / セプチカム / 悪性水腫 / chauvoei / 気腫疽 / ガス壊疽 … More Except Principal Investigator TGF-β / FGF / 遺伝解析 / MSM / BALB / linkage analysis / cataract / animal model / 皮質型白内障 / アポトーシス / EGF / TgE26 / IL-15 / Fas / 疾患モデル動物 / modifier aene / Ms mouse / c mouse / b cac mouse / CF#1 / Ms系マウス / c系マウス / 修飾遺伝子 / 遺伝性白内障 / CF-1系マウス / lens protein / ddY mouse / crystallin / 白内障 / ddY系マウス / 行動解析 / PCR-RFLP / apoptosis suppressor gene / tumor suppressor gene / oncogene / growth factor / apoptosis / cell proliferation / fetal kidney / maternal nephrectomy / vascular endothelial cell growth factor / epidermal growth factor / proliferating cell nuclear antigen / epidermal growth factor receptor / insulin like growth factor1 / 胎児腎臓 / EGFR / WT1 / p53 / アポトーシス抑制遺伝子 / 発癌遺伝子 / 癌抑制遺伝子 / 成長因子 / 細胞増殖 / 胎子腎臓 / 母体片側腎臓摘出 / IL-2 receptor β-chain / delayed implantation / granulated metrial gland cell / uterine NK cell / TNF-α / Fas抗原 / 免疫不全マウス / 細胞外基質レセプター / IL-2レセプター / 脱落膜細胞 / IL-2 ノックアウト / エレーマレセプターβ鎖 / asialo GM1 / IL-2レセプターβ鎖 / IL-2セクターβ鎖 / 着床遅延 / 顆粒性間膜腺細胞 / 子宮NK細胞 / 常染色体劣性遺伝 / 水晶体上皮細胞 / 熱ショック蛋白 / 水晶体上皮 / 水晶体破裂白内障 / 疾患モデルマウス / Bcar3 / 水晶体破裂 / 細胞増殖因子 / 眼内炎 Less

ウェルシュ菌産生壊死毒素(NetB)の鶏壊死性腸炎発症に関与する宿主側因子の特定Principal Investigator
- Principal Investigator
  
  向本雅郁
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Osaka Metropolitan University
Mechanisms of pathogenicities of virulence factors produced by Clostridium perfringens involved in the pathogenesis of chicken necrotic enteritis.Principal Investigator
- Principal Investigator
  
  MUKAMOTO Masafumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Osaka Prefecture University
Investigation of mechanisms of chicken necrotic enterlitis onset by Clostridium perfringens producing necrosis toxin (NetB)Principal Investigator
- Principal Investigator
  
  MUKAMOTO Masafumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Osaka Prefecture University
Development of new cataract model animals: A Study on the lens rupture and endophthalmitis suppression
- Principal Investigator
  
  OKADA Toshiya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Osaka Prefecture University
Investigation of pathogenic mechanisms of new pathogenic factor NetB from Clostridium perfringens that causes avian necrotic entelitis.Principal Investigator
- Principal Investigator
  
  MUKAMOTO Masafumi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied veterinary science
- Research Institution
  Osaka Prefecture University
Investigation of pathophysiologic mechanisms of acute cardiogenic shock by necrotizing toxins from gas gangrene bacilli.Principal Investigator
- Principal Investigator
  
  MUKAMOTO Masafumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied veterinary science
- Research Institution
  Osaka Prefecture University
Investigation of pathogenic manifestative mechanisms of necrotizing toxins from gas gangrene bacilli in malignant edema and blackleg.Principal Investigator
- Principal Investigator
  
  MUKAMOTO Masafumi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied veterinary science
- Research Institution
  Osaka Prefecture University
Characterization of CF-1 cataract mouse as a new animal model
- Principal Investigator
  
  OKADA Toshiya
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Osaka Prefecture University
Characterization of ddY cataract mouse as a new animal model
- Principal Investigator
  
  OKADA Toshiya
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied veterinary science
- Research Institution
  Osaka Prefecture University
Studies on the toxic action of cytolethal toxin from Clostridium septicum.Principal Investigator
- Principal Investigator
  
  MUKAMOTO Masafumi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied veterinary science
- Research Institution
  Osaka Prefecture University
Effects of maternal chronic uremia on the development of fetal kidney : expression of growth factors and genes
- Principal Investigator
  
  OKADA Toshiya
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Osaka Prefecture University
Immune Responses and Roles of Cytokines at the Feto-material Interface during Successful Pregnancy
- Principal Investigator
  
  KISO Yasuo
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Yamaguchi University

All 2021 2017 2016 2014 2013 2011 2010 2008 2007 2005 2004

All Journal Article Presentation Book

[Book] 微生物胞子2011
- Author(s)
  向本雅郁
- Total Pages
  370
- Publisher
  株式会社サイエンスフォーラム
- Data Source
  KAKENHI-PROJECT-21580379
[Book] 微生物胞子(渡部一仁、土戸哲明、坂上吉一編)2011
- Author(s)
  向本雅郁
- Total Pages
  370
- Publisher
  サイエンスフォーラム
- Data Source
  KAKENHI-PROJECT-21580379
[Book] 第52回毒素シンポジウム予稿集(ISSN 1344-9346) 「Clostridium septicum α毒素の新規結合分子の同定」(P64-68)2005
- Author(s)
  向本雅郁
- Total Pages
  178
- Publisher
  第52回毒素シンポジウム世話人神尾好是
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580256
[Book] 第52回毒素シンポジウム予稿集(ISSN 1344-9346) Clostridium septicum α毒素の新規結合分子の同定(P64〜P68)2005
- Author(s)
  向本雅郁
- Total Pages
  178
- Publisher
  第52回毒素シンポジウム世話人神尾好是
- Data Source
  KAKENHI-PROJECT-16580256
[Book] 第53回毒素シンポジウム予稿集(ISSN 1344-9346) 「Clostridium septicum α毒素のpore形成機構の解析」(P16-20)2004
- Author(s)
  向本雅郁
- Total Pages
  158
- Publisher
  第51回毒素シンポジウム世話人平山壽哉
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580256
[Journal Article] The cytotoxicity and molecular mechanisms of the <i>Clostridium perfringens</i> NetB toxin2021
- Author(s)
  Akm Azharul Islam, Mitsuki Nakatani, Takayuki Nakajima, Tomoko Kohda, Masafumi Mukamoto
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 83 Issue: 2 Pages: 187-194
- DOI
  10.1292/jvms.20-0623
- NAID
  130007990717
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06387
[Journal Article] Analysis of tryptophan-rich region in Clostridium septicum alpha-toxin involved with binding to glycosylphosphatidylinositol-anchored proteins.2013
- Author(s)
  Mukamoto M, Kimura R., Hang'ombe M.B., Kohda T., Kozaki S.
- Journal Title
  
  Microbiol Immunol
  
  Volume: 57 Issue: 3 Pages: 163-169
- DOI
  10.1111/1348-0421.12017
- NAID
  40019615121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580449
[Journal Article] Characterization of the D/C mosaic neurotoxin produced by Clostridium botulinum associated with bovine botulism in Japan2010
- Author(s)
  Nakamura K, Kohda T, Umeda K, Yamamoto H, Mukamoto M, Kozaki S
- Journal Title
  
  Vet. Microbiol.
  
  Volume: 140 Pages: 147-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580379
[Journal Article] Idenficatioofthe receptor-binding sites in the carboxyl-terminal half of the heavy chain of botulinum neurotoxin types C and D.2008
- Author(s)
  Tsukamoto, K., Kozai, Y., Ihara, H., Kohda, T, Mukamoto, M., Tsuji, T., Kozaki, S.
- Journal Title
  
  Micro. Pathog 44
  
  Pages: 484-493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580361
[Journal Article] Effect of pH on the conformation nd biological activity of Clostridium septicum alpha-toxin, a pore-forming hemolysin2007
- Author(s)
  Hang' ombe B.M., Kohda, T., Mukamoto, M., Kozaki S.
- Journal Title
  
  Am. J. Anim. Vet. Sci. 2
  
  Pages: 46-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580361
[Presentation] Clostridium perfringens β2毒素の性状解析2017
- Author(s)
  友居瑞栄、幸田知子、向本雅郁
- Organizer
  第160回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08026
[Presentation] 壊死性腸炎起因菌が産生する異なる分子量のNetBと病原性の関連について2016
- Author(s)
  早瀬保奈実、竹中重雄、幸田知子、向本雅郁
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  日本大学生物資源科学部
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-16K08026
[Presentation] 鶏壊死性腸炎原因菌(C. perfringens)が産生する孔形成毒素NetBの細胞傷害機構の解析2014
- Author(s)
  中谷光輝、幸田知子、向本雅郁
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24580449
[Presentation] Clostridium septicumα毒素による心原性ショックのボウタイ生理機構の解明2010
- Author(s)
  向本雅郁、小崎俊司
- Organizer
  第57回トキシンシンポジウム
- Place of Presentation
  滋賀県長浜ロイヤルホテル
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-21580379
[Presentation] Clostridium septicumα毒素による心原性ショックの病態生理機構の解明2010
- Author(s)
  向本雅郁、松村朋恵、幸田知子、小崎俊司
- Organizer
  第57回トキシンシンポジウム
- Place of Presentation
  長浜市
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-21580379
[Presentation] Function analysis of synaptotagmin II as a receptor for Clostridium botulinum type B2008
- Author(s)
  Kohda, T., .Ida, T. Ihara, H., Mukamoto, M., Kozaki, S.
- Organizer
  第8回あわじしま感染症・免疫フォーラム
- Place of Presentation
  淡路島
- Year and Date
  2008-09-08
- Data Source
  KAKENHI-PROJECT-19580361
[Presentation] Character-ization of Clostrtidium botulinum D/C mosaic neurotoxin associated with bovine botul in Japan2008
- Author(s)
  Nakamura, K., Kohda, T., Yamamoto, H., Mukamoto, M., Kozaki, S.
- Organizer
  The 45th Interagency Botulism esearch Coordinating Cmmitte Meting(IBRCC2008)
- Place of Presentation
  philadelphia, USA
- Year and Date
  2008-09-15
- Data Source
  KAKENHI-PROJECT-19580361
[Presentation] 牛ボツリヌス症由来菌神経毒素に特異的な抗原部位の検索と迅速診断法の確立2007
- Author(s)
  幸田知子, 中村佳司, 向本雅郁, 小崎俊司
- Organizer
  第60回日本細菌学会関西支部会
- Place of Presentation
  大阪
- Year and Date
  2007-11-10
- Data Source
  KAKENHI-PROJECT-19580361
[Presentation] 牛ボツリヌス症分離菌株産生毒素の性状解析2007
- Author(s)
  中村佳司, 幸田知子, 向本雅郁, 小崎俊司
- Organizer
  第54回毒素シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2007-09-05
- Data Source
  KAKENHI-PROJECT-19580361

1. OKADA Toshiya (00169111)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. KOZAKI Shunji (10109895)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
3. MATSUYAMA Satoshi (10254442)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. NAKAGAWA Hiroshi (60336807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KONDO Tomohiro (40585238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KISO Yasuo (10142374)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YAMATE Jyoji (50150115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MAKITA Takashi (90035105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KANNAN Yukiko (80264810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MUKAMOTO MASAFUMI 向本 雅郁

MUKAMOTO Masafumi 向本 雅郁

MUKAMOTO Masaya 向本 雅郁

Research Projects

Research Products

Co-Researchers

ウェルシュ菌産生壊死毒素(NetB)の鶏壊死性腸炎発症に関与する宿主側因子の特定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of pathogenicities of virulence factors produced by Clostridium perfringens involved in the pathogenesis of chicken necrotic enteritis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of mechanisms of chicken necrotic enterlitis onset by Clostridium perfringens producing necrosis toxin (NetB)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new cataract model animals: A Study on the lens rupture and endophthalmitis suppression

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of pathogenic mechanisms of new pathogenic factor NetB from Clostridium perfringens that causes avian necrotic entelitis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of pathophysiologic mechanisms of acute cardiogenic shock by necrotizing toxins from gas gangrene bacilli.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of pathogenic manifestative mechanisms of necrotizing toxins from gas gangrene bacilli in malignant edema and blackleg.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization of CF-1 cataract mouse as a new animal model

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization of ddY cataract mouse as a new animal model

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the toxic action of cytolethal toxin from Clostridium septicum.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of maternal chronic uremia on the development of fetal kidney : expression of growth factors and genes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immune Responses and Roles of Cytokines at the Feto-material Interface during Successful Pregnancy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 微生物胞子2011

Author(s)

MUKAMOTO MASAFUMI 向本雅郁

MUKAMOTO Masafumi 向本雅郁

MUKAMOTO Masaya 向本雅郁