SHIMIZU Yasufumi 清水康史

Researcher Number	80242197
Other IDs
Affiliation (based on the past Project Information) *help	2009: 田園都市レディースクリニック, 不妊センター長 2006 – 2008: 東京医科歯科大学, 医学部附属病院, 講師 2002 – 2003: 東京医科歯科大学, 医学部附属病院, 講師 2002: Tokyo Medical & Dental University, Graduate School, Associate Professor, 大学院・医歯学総合研究科, 講師 2000 – 2001: 東京医科歯科大学, 医学部・附属病院, 講師 … More 2000: 東京医科歯科大学, 大学院・医歯学総合研究科, 講師 1998: 東京医科歯科大学, 医学部, 講師 1994 – 1998: 東京医科歯科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Obstetrics and gynecology Except Principal Investigator Obstetrics and gynecology
Keywords	Principal Investigator プロゲステロン / カルシウム / 受精能 / 精子 / progesterone / calcium / fertilizing ability / sperm / hyperactivation / 細胞内情報伝達系 … More / seminal plasma / capacitation / 精漿 / 細胞外基質 / 培養マウス胚盤胞 / H^+ exchanger / 胚盤胞 / レクチン / ITIM / H^+ exchamger / 胚細胞 / 子宮内膜 / H^+ antiporter / Na^+ / 細胞内pH / トロンビン / 着床 / matrix metalloproteinase / 浸潤 / extravillous trophoblast / 栄養膜細胞 / follicular fluid / prostaglandin / signal transduction / 卵胞液 / プロスタグランジン / 受精 / 自動精子分析装置 / 体外受精 / 生殖医学 … More Except Principal Investigator matrix metalloproteinase / 栄養膜細胞 / placenta / Protease-activating receptor / extravillous trophoblast / invasion / trouhoblast / thrombin receptor / thrombin / 脱落膜細胞 / 絨毛外栄養膜 / prothrombinase / protease-activated receptor / matriz metalloproteinase / 増殖と分化 / 胎盤 / protease-activating receptor / 絨毛外栄養膜細胞 / 浸潤 / 栄養膜 / トロンビンレセプター / トロンビン / Intracellular pH / Heparin-binding / Lectin affinity / Extracellular matrix / Fiboronectin / Ectoplacental cone cell / Trophoblast / Blastocyst / フィプロネクチン / 伸展・増殖・分化 / 一次栄養膜細胞 / 細胞内pH / ヘパリン結合物質 / レクチン結合性 / 細胞外基質 / フィブロネクチン / 外胎盤錐細胞 / 培養マウス胚盤胞 Less

Relationship between sperm fertilizing ability and intracellular signal transduction.Principal Investigator
- Principal Investigator
  
  KUBOTA Toshiro, SHIMIZU Yasufumi
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tokyo Medical and Dental University
A research on the role of thrombin receptors in trophoblast invasion
- Principal Investigator
  
  KOI Hideki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tokyo Medical & Dental University
Study of sperm fertilizing ability and intracellular calcium of spermPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Yasufumi
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tokyo Medical and Dental University
着床初期過程における栄養膜細胞と子宮内膜との相互作用に関する研究Principal Investigator
- Principal Investigator
  
  清水康史, 己斐秀樹
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tokyo Medical and Dental University
A Study of sperm fertilizing ability and intracellular calcium.Principal Investigator
- Principal Investigator
  
  SHIMIZU Yasufumi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tokyo Medical and Dental University
Preliminary studies about a symbiotic interaction of trophoblast with endometrium during implantation
- Principal Investigator
  
  ASO Takeshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  TOKYO MEDICAL AND DENTAL UNIVERSITY (TMDU)

All 2010 2009 2008 2007 2006 2004

All Journal Article Presentation

[Journal Article] 常位胎盤早期剥離に至った子宮腺筋症合併不妊症例2009
- Author(s)
  石川智則、原田竜也、清水康史、久保田俊郎
- Journal Title
  
  日本受精着床学会雑誌 26(1)
  
  Pages: 252-254
- Data Source
  KAKENHI-PROJECT-18591796
[Journal Article] Identification of placental leucine aminopeptidase and triton-slowed aminopeptidase N in serum of pregnant women.2009
- Author(s)
  Kawai M, Araragi K, 清水康史, Hara Y
- Journal Title
  
  Clin Chim Acta. 400
  
  Pages: 37-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591796
[Journal Article] 当院における配偶者間人工授精(intrauterine insemination:IUI)の治療成績2009
- Author(s)
  岩田未菜、清水康史、吉木尚之、原田竜也、石川智則、宮坂尚幸、尾林聡、久保田俊郎
- Journal Title
  
  日本受精着床学会雑誌 26(1)
  
  Pages: 118-122
- Data Source
  KAKENHI-PROJECT-18591796
[Journal Article] 当院における配偶者間人工授精(intrauterine insemination : IUI)の治療成績2009
- Author(s)
  岩田未菜、清水康史、吉木尚之、原田竜也、石川智則、宮坂尚幸、尾林聡、久保田俊郎
- Journal Title
  
  日本受精着床学会雑誌 26
  
  Pages: 118-122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591796
[Journal Article] Identification of placental leucine aminopeptidase and triton-slowed aminopeptidase N in serum of pregnant women.2009
- Author(s)
  Kawai M, Araragi K, 清水康史, Hara Y
- Journal Title
  
  Clin Chim Acta 400
  
  Pages: 37-41
- Data Source
  KAKENHI-PROJECT-18591796
[Journal Article] 月経異常.症候別患者さんを上手に診るコツ2009
- Author(s)
  清水康史、久保田俊
- Journal Title
  
  JUNIOR 480
  
  Pages: 35-42
- Data Source
  KAKENHI-PROJECT-18591796
[Journal Article] Increase in the concentration of cytosolic-free calcium induced by human follicular fluid was decreased in single human spermatozoa with abnormal morphology.2008
- Author(s)
  Shimizu Y, Minagichi R, Ishikawa T, Harada T, Yoshiki N, Kubota T
- Journal Title
  
  Reproductive Medicine and Biology 7
  
  Pages: 143-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591796
[Journal Article] Increase in the concentration of cytosolic-free calcium induced by human follicular fluid was decreased in single human spermatozoa with abnormal morphology2008
- Author(s)
  Shimizu Y, Minagichi R, Ishikawa T, Harada T, Yoshiki N, Kubota T
- Journal Title
  
  Reproductive Medicine and Biology 7
  
  Pages: 143-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591796
[Journal Article] Increase in the concentration of cytosolic-free calcium induced by human follicular fluid was decreased in single human spermatozoon with abnormal morphology2008
- Author(s)
  清水康史, Minaguchi R, 石川智則, 原田竜也, Yoshiki N, 久保田俊郎
- Journal Title
  
  Reproductive Medicine and Biology 7
  
  Pages: 143-149
- NAID
  10023968469
- Data Source
  KAKENHI-PROJECT-18591796
[Journal Article] Methylat ion of the calcium channel-related gene, CACNA2D3, is freouent and a poor prognostic factor in gastric cancer.2008
- Author(s)
  Wanajo A, Sasaki A, Nagasaki H, Shimida S, Otubo T, Owaki S, Shimizu Y, Eishi Y, Kojima K, Nakajima Y, Kawano T, Yuasa Y, Akiyama Y
- Journal Title
  
  Gastroenterology 135
  
  Pages: 580-590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591796
[Journal Article] Methylation of the Calcium Channel-Related Gene, CACNA2D3, Is Frequent and a Poor Prognostic Factor in Gastric Cancer2008
- Author(s)
  Wanajo A, Sasaki A, Nagasaki H, Shimada S, Otsubo T, Owaki S, 清水康史, Eishi Y, Kojima K, Nakajima Y, Kawano T, Yuasa Y, Akiyama Y
- Journal Title
  
  Gastroenterology 135
  
  Pages: 580-590
- Data Source
  KAKENHI-PROJECT-18591796
[Journal Article] Methylation of the calcium channel-related gene, CACNA2D3, is frequent and a poor prognostic factor in gastric cancer2008
- Author(s)
  Wanajo A, Sasaki A, Nagasaki H, Shimida S, Otubo T, Owaki S, Shimizu Y, Eishi Y, Kojima K, Nakajima Y, Kawano T, Yuasa Y, Akiyama Y
- Journal Title
  
  Gastroent erology 135
  
  Pages: 580-590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591796
[Journal Article] 体外受精、ICSIの適応.2007
- Author(s)
  清水康史、久保田俊郎
- Journal Title
  
  よくわかる臨床不妊症学(中外医学社)
  
  Pages: 118-124
- Data Source
  KAKENHI-PROJECT-18591796
[Journal Article] 不妊症例における腹腔鏡後の妊娠に関する検討2006
- Author(s)
  堀出由里、清水康史、原田竜也、己斐秀樹、尾林聰、坂本秀一、久保田俊郎、麻生武志、多田雅人
- Journal Title
  
  産婦人科の実際 55(7)
  
  Pages: 1175-1178
- Data Source
  KAKENHI-PROJECT-18591796
[Journal Article] Impaired hyperactivation of human sperm in patients with infertility.2004
- Author(s)
  Munire M, Shimizu Y, Sakata Y, Minaguchi R, Aso T.
- Journal Title
  
  J Med Dent Sci. 51(1)
  
  Pages: 99-104
- NAID
  110000076057
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12671583
[Presentation] 抗精子不動化抗体陽性女性の体外受精成績について2010
- Author(s)
  清水康史、村松裕崇、有地あかね、河村真紀子、依光毅、許山浩司、大原基弘、河村寿宏
- Organizer
  第55回日本生殖医学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-18591796
[Presentation] 抗精子不動化抗体陽性女性の妊娠転帰2010
- Author(s)
  清水康史、大原基弘、許山浩司、依光毅、河村寿宏
- Organizer
  第28回日本受精着床学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18591796
[Presentation] Relationship between the time interval from semen collection to sperm wash and IUT outcome2009
- Author(s)
  Y.Shimizu, T.Yorimitsu, H.Motoyama, M.Ohara, T.Kawamura
- Organizer
  65^<th> Annual Meeting of American Society of Reproductive Medicine
- Place of Presentation
  Atlanta, USA
- Year and Date
  2009-10-20
- Data Source
  KAKENHI-PROJECT-18591796
[Presentation] 子宮内膜症症例の体外受精における精子自動精子分析装置(CASA・SQA)の意義2008
- Author(s)
  原田竜也、清水康史、岩田未菜、石川智則、久保田俊郎
- Organizer
  第53回日本生殖医学会総会・学術講演会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-18591796
[Presentation] 体外受精における精子自動分析装置(CASA・SQA)の意義のついての検討2008
- Author(s)
  原田竜也、清水康史、岩田未菜、田島麻記子、石川智則、久保田俊郎
- Organizer
  第60回日本産科婦人科学会学術講演会
- Place of Presentation
  横浜
- Year and Date
  2008-04-13
- Data Source
  KAKENHI-PROJECT-18591796
[Presentation] 体外受精における精子自動精子分析装置(CASA・SQA)の意義についての検討2008
- Author(s)
  原田竜也、清水康史、岩田未菜、田島麻記子、石川智則、久保田俊郎
- Organizer
  第60回日本産科婦6人科学会学術講演会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18591796
[Presentation] 当院における配偶者間人工授精の治療成績2007
- Author(s)
  岩田未菜、清水康史、他
- Organizer
  第59回日本産科婦人科学会
- Place of Presentation
  京都
- Year and Date
  2007-04-16
- Data Source
  KAKENHI-PROJECT-18591796
[Presentation] 子宮腺筋症と不妊症の関連についての検討2007
- Author(s)
  石川智則、田島麻記子、原田竜也、吉木尚之、清水康史、久保田俊郎
- Organizer
  第11回産婦人科臨床フォーラム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18591796
[Presentation] 当院における配偶者間人工授精(AIH)の治療成績2007
- Author(s)
  岩田未菜、清水康史、原田竜也、石川智則、宮坂尚幸、尾林聰、久保田俊郎
- Organizer
  第25回日本受精着床学会総会・学術講演会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-18591796
[Presentation] Pregnancy Rates of Intrauterine Insemination (IUI)2007
- Author(s)
  岩田未菜, 清水康史, 原田竜也、石川智則、宮坂尚幸、尾林聡、久保田俊郎 Analysis of Factors Influencing
- Organizer
  第20回アジア・オセアニア産婦人科学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18591796
[Presentation] 当院における配偶者間人工授精(AIH)の治療成績2007
- Author(s)
  岩田未菜、清水康史、原田竜也、石川智則、宮坂尚幸、尾林聡、久保田俊郎
- Organizer
  第59回日本産科婦人科学会学術講演会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18591796
[Presentation] 重度の子宮腺筋症合併妊娠で生児を得た一例2006
- Author(s)
  清水康史、田島麻記子、久保田俊郎、麻生武志
- Organizer
  第58回日本産科婦人科学会学術講演会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18591796

1. KUBOTA Toshiro (50126223)

# of Collaborated Projects: 7 results

# of Collaborated Products: 17 results
2. KOI Hideki (20280969)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. ASO Takeshi (60093176)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
4. HARADA Tatsuya (80376748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
5. ISIKAWA Tomonori (50447489)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
6. OBAYASHI Satoshi (10262180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KAMATA Suusaku (80169606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 河村寿宏 (80262179)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 坂本秀一 (90242198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 中尾幸恵 (50301156)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 坂田優 (10334442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIMIZU Yasufumi 清水 康史

Research Projects

Research Products

Co-Researchers

Relationship between sperm fertilizing ability and intracellular signal transduction.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A research on the role of thrombin receptors in trophoblast invasion

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of sperm fertilizing ability and intracellular calcium of spermPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

着床初期過程における栄養膜細胞と子宮内膜との相互作用に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A Study of sperm fertilizing ability and intracellular calcium.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Preliminary studies about a symbiotic interaction of trophoblast with endometrium during implantation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 常位胎盤早期剥離に至った子宮腺筋症合併不妊症例2009

Author(s)

Journal Title

Data Source

[Journal Article] Identification of placental leucine aminopeptidase and triton-slowed aminopeptidase N in serum of pregnant women.2009

Author(s)

Journal Title

Data Source

[Journal Article] 当院における配偶者間人工授精(intrauterine insemination:IUI)の治療成績2009

Author(s)

Journal Title

Data Source

[Journal Article] 当院における配偶者間人工授精(intrauterine insemination : IUI)の治療成績2009

Author(s)

Journal Title

Data Source

[Journal Article] Identification of placental leucine aminopeptidase and triton-slowed aminopeptidase N in serum of pregnant women.2009

Author(s)

Journal Title

Data Source

[Journal Article] 月経異常.症候別患者さんを上手に診るコツ2009

Author(s)

Journal Title

Data Source

[Journal Article] Increase in the concentration of cytosolic-free calcium induced by human follicular fluid was decreased in single human spermatozoa with abnormal morphology.2008

Author(s)

Journal Title

Data Source

[Journal Article] Increase in the concentration of cytosolic-free calcium induced by human follicular fluid was decreased in single human spermatozoa with abnormal morphology2008

Author(s)

Journal Title

Data Source

[Journal Article] Increase in the concentration of cytosolic-free calcium induced by human follicular fluid was decreased in single human spermatozoon with abnormal morphology2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Methylat ion of the calcium channel-related gene, CACNA2D3, is freouent and a poor prognostic factor in gastric cancer.2008

Author(s)

Journal Title

SHIMIZU Yasufumi 清水康史