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HIRATSUKA Koichi  平塚 浩一

ORCIDConnect your ORCID iD *help
… Alternative Names

平塚 浩一  ヒラツカ コウイチ

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Researcher Number 80246917
Other IDs
External Links
Affiliation (Current) 2025: 日本大学, 松戸歯学部, 教授
Affiliation (based on the past Project Information) *help 2021 – 2023: 日本大学, 松戸歯学部, 教授
2014 – 2019: 日本大学, 松戸歯学部, 教授
2011 – 2013: 日本大学, 松戸歯学部, 准教授
2012: 日本大学, 歯学部, 准教授
2010: 日本大学, 松戸歯学部 … More
2001 – 2009: 日本大学, 松戸歯学部, 講師
1997 – 1999: 日本大学, 松戸歯学部, 助手
1993: 日本大学, 松戸歯学部, 助手 Less
Review Section/Research Field
Principal Investigator
Periodontology / Periodontal dentistry / 病態科学系歯学(含放射線系歯学) / Basic Section 57030:Conservative dentistry-related / Functional basic dentistry / Morphological basic dentistry
Except Principal Investigator
Surgical dentistry / Functional basic dentistry / Periodontology / Periodontal dentistry
Keywords
Principal Investigator
遺伝子発現 / 歯周病 / 細菌 / マイクロアレイ / 病原性 / 診断 / Porphyromonas gingivalis / クローニング / 微生物 / in vitro transcription … More / microarray / 口腔細菌 / 次世代シークエンス / 原核生物 / Red complex / 遺伝子 / ストレス / 核酸 / non-coding RNA / カンジダ / 光線力学治療 / Candida albicans / 抗菌的光線力学治療 / Candida albican / a-PDT / レーザー / LED / 抗菌的光線力学療法 / バイオテクノロジー / 病原細菌 / non-coding RNAs / 遺伝子解析 / red complex / 発現 / マーカー / gene expression / prokaryote / primer / RNA amplification / In vitro transcription / プライマー / RNA増幅 / environment / examination / transcriptome / pathogen / periodontal disease / チップ / 解析 / ヘミン / 蛍光標識 / リアルタイムPCR / 酸化ストレス / 増殖 / P. gingivalis / ポルフィロモナス ジンジバリス / 環境 / 検査 / トランスクリプトーム / NGS / 発現調節 / ncRNA / RNA / カタログ化 / 臨床サンプル / アレイ / 病態 / サブトラクション / cDNA / Streptococus mutans / 酸 / ストレス蛋白質 / Subtraction / Streptococcus mutans / 欠損株 / 接合 / エレクトロポレーション / 外膜タンパク質 … More
Except Principal Investigator
DNAマイクロアレイ / cDNA / interleukin-1β / HLA / レーザー / Porphyromonas gingivalis / インプラント周囲炎 / 歯周ポケット / 歯周炎 / 殺菌 / aPDT / 光 / PCNA / マイクロCT / 上皮化 / 創傷治癒促進 / 低出力レーザー治療 / 半導体レーザー / 高繰り返しパルス発振 / 抜歯窩 / 細菌 / 細胞 / LED / Pathway Analysis / GeneChip / synovial fibroblasts / temporomandibular joint / IL-1β / ヒト顎間接滑膜細胞 / 顎関節症 / out growth法 / interluekin-1β / GeneChip microarray / Pathway解析 / GeneChip解析 / ヒト顎関節滑膜細胞 / 顎関節 / Pathway analysis / CeneChip / 培養ヒト顎関節滑膜細胞 / 顎関節内障 / chemokine / transcutaneous immunization / nasal immunization / intestinal immune response / isolated lymphoid follicle / villus M cell / oral lichen planus / リンホトキシン / Id2 / NALT / 粘膜免疫 / サイトカイン / IgA抗体応答 / 腸管関連リンパ組織 / マイクロダイセクション / 口腔扁平苔癬 / ケモカイン / 経皮免疫 / 経鼻免疫 / 腸管免疫応答 / 孤立リンパ小節 / 絨毛M細胞 / 口腔扁平苔蘚 / Laser / Osteoblast / Gingival ligament / Gingival fibroblast / Gingival epithelium cell / Periodontal disease / DNA microarray / 蛍光標識 / 歯根膜 / エムドゲイン / 再生 / 病態 / トランスクリプトーム / 線維芽細胞 / 上皮細胞 / マイクロアレイ / Gene-Chip / cDNAマイクロアレイ / 低出力レーザー / 遺伝子発現 / 幹細胞 / 骨芽細胞 / 歯根膜細胞 / 歯肉線維芽細胞 / 歯肉上皮細胞 / 歯周病 / deficient mutant / subtruction / 遺伝子ライブラリー / 原核細胞 / クローニング / 差分化 / subtraction / 欠損株 / サブトラクション / マイクロストラクチャー / Er:YAGレーザー / a-PDT / 青色LED / 細胞増殖 / チタン / Er:YAG レーザー Less
  • Research Projects

    (15 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (32 People)
  •  In vitro study on effects of antimicrobial photodynamic therapy against bacterial pathogenicityPrincipal Investigator

    • Principal Investigator
      平塚 浩一
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57030:Conservative dentistry-related
    • Research Institution
      Nihon University
  •  A study of the diagnostic markers for periodontal disease by the comprehensive gene expression analyses of red complex bacteriaPrincipal Investigator

    • Principal Investigator
      HIRATSUKA, Koichi
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontology
    • Research Institution
      Nihon University
  •  A bacterial non-coding RNAs search and the dynamics in serious periodontal diseasePrincipal Investigator

    • Principal Investigator
      HIRATSUKA, Koichi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontology
    • Research Institution
      Nihon University
  •  Development of phototherapy using lasers and LEDs for the treatment and prevention of periodontitis and peri-implantitis

    • Principal Investigator
      AOKI AKIRA
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontology
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of innovative treatment methods using light energy for periodontitis and peri-implantitis

    • Principal Investigator
      AOKI Akira
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  Categorization of the bacterial non-coding RNAs and development of the custom arrayPrincipal Investigator

    • Principal Investigator
      HIRATSUKA Koichi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Nihon University
  •  A development of the custom array for diagnoses to predict a risk of the periodontal-diseasePrincipal Investigator

    • Principal Investigator
      HIRATSUKA Koichi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Nihon University
  •  Development of diagnostics for direct monitoring the pathogenicity of oral bacterium in periodontal pocketsPrincipal Investigator

    • Principal Investigator
      HIRATSUKA Koichi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nihon University
  •  Comprehensive bioinformatics analysis of oral lichen planus

    • Principal Investigator
      OTAKE Shigeo
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Nihon University
  •  Gene expression profiling of IL-1β-stimulated synovial cells from TMJ using Gene Chip

    • Principal Investigator
      OGURA Naomi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Nihon University
  •  by using DNA microarray

    • Principal Investigator
      ABIKO Yoshimitsu
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nihon University
  •  Construction of the custom-made DNA chip for pathogenic diagnosis of bacteria related with periodontal diseasePrincipal Investigator

    • Principal Investigator
      HIRATSUKA Koichi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Nihon University
  •  ストレプトコッカスミュータンス酸ストレス蛋白質の遺伝子クローニングPrincipal Investigator

    • Principal Investigator
      平塚 浩一
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Nihon University
  •  A construction of cDNA library and categorization of genes by subtraction in prokaryote - A gene cloning of new known gene associated with pathogenic factors in P. gingivalis-

    • Principal Investigator
      ABIKO Yoshimitsu
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nihon University School of Dentistry at Matsudo
  •  P.gingivalis 40-kDa外膜タンパク質の生理的機能Principal Investigator

    • Principal Investigator
      平塚 浩一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Nihon University

All 2015 2014 2013 2012 2010 2008 2007 2005 2004 Other

All Journal Article Presentation Patent

  • [Journal Article] 歯周病治療におけるa-PDTの基礎研究の現状2015

    • Author(s)
      青木 章,竹内康雄,平塚 浩一,CHUI Chanthoeun,一ノ瀬顕子,上窪彩乃,和泉雄一
    • Journal Title

      歯科評論

      Volume: 75 Pages: 47-55

    • Data Source
      KAKENHI-PROJECT-25463212
  • [Journal Article] Antimicrobial effect of photodynamic therapy using high-power blue light-emitting diode and red-dye agent on Porphyromonas gingivalis.2013

    • Author(s)
      Chui C
    • Journal Title

      J Periodontal Res

      Volume: 10 Issue: 6 Pages: 1-10

    • DOI

      10.1111/jre.12055

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390497, KAKENHI-PROJECT-22592308, KAKENHI-PROJECT-25463212
  • [Journal Article] Gene expression profiling during growth in vitro using a custom-made Porphyromonas gingivalis gene array.2012

    • Author(s)
      Hiratsuka K
    • Journal Title

      Int J Oral-Med Sci

      Volume: 11 Pages: 141-150

    • NAID

      130003375166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592320
  • [Journal Article] Blue LED inhibits the growth of Porphyromonas gingivalis by suppressing the expression of genes associated with DNA replication and cell division.2012

    • Author(s)
      Chui C
    • Journal Title

      Lasers Surg Med

      Volume: 44 Issue: 10 Pages: 856-864

    • DOI

      10.1002/lsm.22090

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390497, KAKENHI-PROJECT-22592308
  • [Journal Article] Gene expression profiling during growth in vitro using a custom-made Porphyromonas gingivalis gene array2012

    • Author(s)
      Hiratsuka K, Abiko Y
    • Journal Title

      Int J Oral-Med Sci

      Volume: 11(3) Pages: 141-150

    • NAID

      130003375166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592320
  • [Journal Article] Hemin-binding protein 35 (HBP35) plays an important role in bacteria-mammalian cells interactions in Porphyromonas gingivalis.2010

    • Author(s)
      Hiratsuka K, Kiyama-Kishikawa M, Abiko Y
    • Journal Title

      Microb Pathog 48(3-4)

      Pages: 116-123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592396
  • [Journal Article] Hemin-binding protein 35(HBP35)plays an important role in bacteria-mammalian cells interactions in Porphyromonas gingivalis2010

    • Author(s)
      Hiratsuka K
    • Journal Title

      Microb Pathog 48

      Pages: 116-123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592396
  • [Journal Article] Role of the hemin-binding protein 35 (HBP35) of Porphyromonas gingivalis in coaggregation.2008

    • Author(s)
      Hiratsuka K, Hayakawa M, Kiyama-Kishikawa M, Sasaki Y, Hirai T, Abiko Y
    • Journal Title

      Microb Pathog 44(4)

      Pages: 320-328

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592396
  • [Journal Article] Oligonucleotide array analysis of cyclic tension-responsive genes in human periodontal ligament fibroblasts.2007

    • Author(s)
      Yamashiro K, Myokai F, Hiratsuka K, Yamamoto T, Senoo K, Arai H, Nishimura F, Abiko Y, Takashiba S
    • Journal Title

      Int J Biochem & Cell Biol 39(5)

      Pages: 910-921

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592396
  • [Patent] プロモーター領域を付加したプライマー2005

    • Inventor(s)
      平塚 浩一, 安孫子 宜光, 岸川 道子
    • Industrial Property Rights Holder
      平塚 浩一, 安孫子 宜光, 岸川 道子
    • Filing Date
      2005-10-14
    • Data Source
      KAKENHI-PROJECT-16591867
  • [Patent] プロモーター領域を付加したプライマー2004

    • Inventor(s)
      平塚 浩一, 安孫子 宜光, 岸川 道子
    • Industrial Property Rights Holder
      平塚 浩一, 安孫子 宜光, 岸川 道子
    • Industrial Property Number
      2004-299976
    • Filing Date
      2004-10-14
    • Data Source
      KAKENHI-PROJECT-16591867
  • [Patent] プロモーター領域を付加したプライマー2004

    • Inventor(s)
      平塚浩一 他2名
    • Industrial Property Rights Holder
      CUBIC
    • Industrial Property Number
      2004-299976
    • Filing Date
      2004
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591867
  • [Presentation] Non-coding RNA in Porphyromonas gingivalis.2015

    • Author(s)
      Hiratsuka K, Abiko Y
    • Organizer
      93rd General Session & Exhibition of the IADR
    • Place of Presentation
      Hynes Convention Center, Boston, USA
    • Year and Date
      2015-03-14
    • Data Source
      KAKENHI-PROJECT-25463230
  • [Presentation] 歯周病治療におけるa-PDTの基礎研究の現状2015

    • Author(s)
      青木 章,竹内康雄,平塚浩一,CHUI Chanthoeun,一ノ瀬顕子,上窪彩乃,和泉雄一
    • Organizer
      第36回日本レーザー医学会
    • Place of Presentation
      栃木県総合文化センター(栃木県宇都宮市)
    • Year and Date
      2015-10-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-25463212
  • [Presentation] Porphyromonas gingivalisに対するBlue LEDとRose Bengalを併用した抗菌効果は酸素の存在により増強される2014

    • Author(s)
      上窪彩乃, 平塚浩一, 青木 章, 竹内康雄, 大川原直子,安孫子宜光, 和泉雄一
    • Organizer
      第57回秋季日本歯周病学会学術大会
    • Place of Presentation
      神戸国際展示場,神戸
    • Year and Date
      2014-10-19
    • Data Source
      KAKENHI-PROJECT-25463212
  • [Presentation] 抗菌光線力学療法がPorphyromonas gingivalisの増殖に及ぼす影響について2013

    • Author(s)
      上窪 彩乃,平塚 浩一,青木 章,竹内 康雄,安孫子 宣光,和泉 雄一
    • Organizer
      2013年度日本歯科保存学会秋季学術大会(第139回)
    • Place of Presentation
      秋田県秋田市秋田県総合生活文化会館(アトリオン)
    • Data Source
      KAKENHI-PROJECT-25463212
  • [Presentation] Effect of blue LED with Rose Bengal on Porphyromonas gingivalis2013

    • Author(s)
      Uekubo A, Hiratsuka K, Aoki A, Takeuchi Y, Abiko Y, Izumi Y
    • Organizer
      Penn Periodontal Conference 2013
    • Place of Presentation
      University of Pennsylvania, Philadelphia, USA
    • Data Source
      KAKENHI-PROJECT-25463212
  • [Presentation] A study of 16S rRNA for bacterial gene expression analysis2013

    • Author(s)
      Hiratsuka K, Abiko Y
    • Organizer
      第91回国際歯科学会
    • Place of Presentation
      アメリカ・シアトル.
    • Year and Date
      2013-03-22
    • Data Source
      KAKENHI-PROJECT-22592320
  • [Presentation] 歯科医学へのバイオインフォーマティクスの応用2008

    • Author(s)
      安孫子宜光・柴田恭子・平塚浩一・岡野総一郎
    • Organizer
      第21回日本歯科医学会総会
    • Place of Presentation
      神奈川(横浜)
    • Year and Date
      2008-11-16
    • Data Source
      KAKENHI-PROJECT-19592396
  • [Presentation] Novel roles of Ten-m/Odz3 in development of mandibular condylar cartilage.2008

    • Author(s)
      T. MURAKAMI, T. FUKUNAGA, N. TAKESHITA, K. HIRATSUKA, T. YAMASHIRO, Y. ABIKO, T. TAKANO-YAMAMOTO
    • Organizer
      IADR
    • Place of Presentation
      Toronto
    • Year and Date
      2008-02-04
    • Data Source
      KAKENHI-PROJECT-19592396
  • [Presentation] A study of 16S rRNA for bacterial gene expression analysis

    • Author(s)
      Hiratsuka K
    • Organizer
      第91回国際歯科学会
    • Place of Presentation
      アメリカ、シアトル
    • Data Source
      KAKENHI-PROJECT-22592320
  • [Presentation] The influence of oxygen in blue LED irradiation with Rose Bengal on the growth of Porphyromonas gingivalis

    • Author(s)
      Uekubo A, Hiratsuka K, Aoki A, Takeuchi Y, Abiko Y, Isumi Y
    • Organizer
      14th Congress of the World Federation for Laser Dentistry
    • Place of Presentation
      Paris, France
    • Year and Date
      2014-06-02 – 2014-06-04
    • Data Source
      KAKENHI-PROJECT-25463212
  • [Presentation] 環境ストレスに応答するP. gingivalis non-coding RNAの検索

    • Author(s)
      平塚 浩一
    • Organizer
      第55回歯科基礎医学会学術大会・総会
    • Place of Presentation
      岡山・岡山コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-25463230
  • 1.  ABIKO Yoshimitsu (70050086)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  KIYAMA Michiko (50256905)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  AOKI Akira (30302889)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 4.  KOBAYASHI Hiroaki (50396967)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  TAKEUCHI Yasuo (60396968)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 6.  AKIZUKI Tatsuya (50401378)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  MIZUTANI Koji (60451910)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  OHSHIMA Mitsuhiro (30194145)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  KOMAKI Motohiro (30401368)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  IWASAKI Kengo (40401351)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  TANIGUCHI Yoichi (30648093)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  OGURA Naomi (10152448)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  SCHWARZ Frank
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  SCULEAN Anton
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  YAMAGUCHI Yoko (00239922)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  ICHINOSE Shizuko (60014156)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  SHIROZA Teruaki (50271333)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SAITO Shigeno (60072394)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  OTAKE Shigeo (20050031)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  YAMAMOTO Masafumi (80210558)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  Tsuchida Sachio (90410422)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  名倉 英明 (80013960)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  SAWABE Masanori
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  EJIRI Kenichiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  OGITA Mayumi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  SATO Ikufumi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  TSUBOKAWA Masaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  EDUARD Carlos
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  ALEKSIC Verica
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  ALMEHDI Aslam
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  CHUI Chanthoeun
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  Coluzzi Donald J.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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