Yoshida Akira 吉田明

… Alternative Names

吉田明ヨシダアキラ

YOSHIDA Akira 吉田明

吉田朗ヨシダアキラ

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Researcher Number	80252005
Other IDs
External Links
Affiliation (Current)	2025: 国際医療福祉大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2017 – 2019: 国際医療福祉大学, 医学部, 教授 2016: 国際医療福祉大学, 薬学部, 教授 2011: 福井大学, 医学部・附属病院, 講師 2005 – 2011: 福井大学, 医学部附属病院, 講師 1999 – 2001: 福井医科大学, 医学部, 助手 1994 – 1995: 福井医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Hematology / Hematology / Medical pharmacy Except Principal Investigator Hematology
Keywords	Principal Investigator アポトーシス / Apoptosis / 白血病細胞 / 白血病 / Survivin / Bcl-2 / HSP90阻害剤 / 抗アポトーシス分子 / Venetoclax / 静止期 … More / 幹細胞 / Mcl-1 / medical treatment / Leukemia / Survivin-3B / 治療 / AN34 / endonuclease / Caspase3 / AN-34 / Caspase 3 / エンドヌクレアーゼ / Caspase-3 / AP-ENDONUCLEASE / Endonuclease / Beclin-1 / ABT-737 / LC-II / オートファジー / 濾胞性リンパ腫 / プロテアーゼ / トポイソメラーゼ阻害剤 … More Except Principal Investigator 薬物動態的自己増強 / 薬理学 / 薬剤反応性 / temozolomide / P2RY5 / 5'-nucleotidase II / ara-CTP / Bcl-2 / Glutathione S-trans ferase μ / 薬学 / 内科 / 癌 / GSTM1 / イダルビシン / シタラビン / テーラーメイド治療 / ゲノム薬理学 / 薬剤耐性 / 白血病 Less

Molecular targeted therapy against leukemia stem cells via inhibition of anti-apoptotic proteinsPrincipal Investigator
- Principal Investigator
  
  Yoshida Akira
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  International University of Health and Welfare
Molecular mechanism of autophagy in follicular lymphoma cellsPrincipal Investigator
- Principal Investigator
  
  YOSHIDA Akira
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Fukui
Tailor-made therapy based on pharmacogenomic strategy for refractory leukemia due to multifactorial drug resistance
- Principal Investigator
  
  UEDA Takanori
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Fukui
Survivin-directed RNA interference is a potent suppressor of leukemia growthPrincipal Investigator
- Principal Investigator
  
  YOSHIDA Akira
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Fukui
Cloning of new endonuclease (AN34) involved in apoptosis.Principal Investigator
- Principal Investigator
  
  YOSHIDA Akira
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Fukui Medical University
抗腫瘍剤による白血病細胞のアポトーシスに関与するエンドヌクレアーゼの同定Principal Investigator
- Principal Investigator
  
  吉田朗
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  福井医科大学
トポイソメラーゼ阻害剤による白血病細胞のアポトーシス誘発機構の解明Principal Investigator
- Principal Investigator
  
  吉田明
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  福井医科大学

All 2019 2018 2017 2016 2012 2011 2010 2009 2007 2006 2005 2004

All Journal Article Presentation Book

[Book] 白血病・リンパ腫・骨髄腫-今日の診断と治療.第4版2011
- Author(s)
  吉田明, 上田孝典
- Publisher
  中外医薬社
- Data Source
  KAKENHI-PROJECT-21591196
[Book] 2.造血器腫瘍の治療.総論A化学療法剤.2011
- Author(s)
  吉田明,上田孝典
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-21591196
[Book] 分子標的治療5.ボルテゾミブ.2009
- Author(s)
  吉田明,上田孝典
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-21591196
[Journal Article] Bcl-2阻害剤ベネトクラクス(Venetoclax)の慢性リンパ性白血病および急性骨髄性白血病に対する優れた臨床効果2019
- Author(s)
  吉田　明
- Journal Title
  
  BIO Clinica
  
  Volume: 34(6) Pages: 97-100
- Data Source
  KAKENHI-PROJECT-16K08410
[Journal Article] YM155 exerts potent cytotoxic activity against quiescent (G0/G1) multiple myeloma and bortezomib resistant cells via inhibition of survivin and Mcl-12017
- Author(s)
 Ookura Miyuki、Fujii Tatsuya、Yagi Hideki、Ogawa Takuya、Kishi Shinji、Hosono Naoko、Shigemi Hiroko、Yamauchi Takahiro、Ueda Takanori、Yoshida Akira
- Journal Title
 
 Oncotarget
 
 Volume: 8 Issue: 67 Pages: 111535-111550
- DOI
 10.18632/oncotarget.22871
- NAID
 120006469617
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-16K08409, KAKENHI-PROJECT-16K08410
[Journal Article] The combination of panobinostat with ponatinib synergistically overcomes imatinib-resistant CML cells.2016
- Author(s)
  Matsuda Y, Yamauchi T, Hosono N, Uzui K, Negoro E, Morinaga K, Nishi R, Yoshida A, Kimura S, Maekawa T, Ueda T
- Journal Title
  
  Cancer Sci.
  
  Volume: 107 Issue: 7 Pages: 1029-1038
- DOI
  10.1111/cas.12965
- NAID
  120005822784
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07171, KAKENHI-PROJECT-16K08410
[Journal Article] Marked upregulation of Survivin and Aurora-B kinase are associated with disease progression in the myelodysplastic syndromes2012
- Author(s)
  Yoshida A, Zokumasu K, Wano Y, Yamauchi T, Imamura S, Takagi K, Kishi S, Urasaki Y, Tohyama K, Ueda T
- Journal Title
  
  Haematologica
  
  Volume: 97 Issue: 9 Pages: 1372-1379
- DOI
  10.3324/haematol.2011.055681
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591196
[Journal Article] Camptothecin induces DNA strand breaks and is cytotoxic in stimulated normal lymphocytes.2011
- Author(s)
  Yamauchi, T., Yoshida, A., Ueda T
- Journal Title
  
  Oncol Rep
  
  Volume: 25 Pages: 347-352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591196
[Journal Article] Camptothecin induces DNA strand breaks and is cytotoxic in stimulated normal lymphocytes2011
- Author(s)
  Yamauchi T, Yoshida A, Ueda T
- Journal Title
  
  Oncol Rep
  
  Volume: 25(2) Issue: 2 Pages: 347-52
- DOI
  10.3892/or.2010.1100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591196
[Journal Article] Glutathione S-transferase M1 inhibits dexamethasone-induced apoptosis in association with the suppression of Bim through dual mechanisms in a lymphoblastic leukemia cell line2010
- Author(s)
  N.Hosono, S.Kishi, S.Iho, Y.Urasaki, A.Yoshida, H.Kurooka, Y.Yokota, T.Ueda
- Journal Title
  
  Cancer Sci 101(3)
  
  Pages: 767-773
- NAID
  10026589943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591102
[Journal Article] Glutathione S-transferase M1 inhibits dexamethasone-induced apoptosis in association with the suppression of Bim through dual mechanisms in a lymphoblastic leukemia cell line2010
- Author(s)
  N. Hosono, S. Kishi, S. Iho, Y. Urasaki, A. Yoshida, H. Kurooka, Y. Yokota, T. Ueda
- Journal Title
  
  Cancer Sci 101
  
  Pages: 767-773
- NAID
  10026589943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591102
[Journal Article] Glutathione S-transferase M1 inhibits dexamethasone-induced apoptosis in association with the suppression of Bim through dual mechanisms in a lymphoblastic leukemia cell line.2010
- Author(s)
  Hosono N, Kishi S, Iho S, Urasaki Y, Yoshida A, Kurooka H, Yokota Y, Ueda T.
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 767-73
- NAID
  10026589943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591196
[Journal Article] Glutathione S-transferase M1 inhibits dexamethasone-induced apoptosis in association with the suppression of Bim through dual mechanisms in a lymphoblastic leukemia cell line2010
- Author(s)
  Hosono, N., Kishi, S., Iho, S., Urasaki, Y., Yoshida, A., Kurooka, H., Yokota, Y., Ueda, T
- Journal Title
  
  Cancer Sci.
  
  Volume: 101(3) Pages: 767-773
- NAID
  10026589943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591196
[Journal Article] Intracellular cytarabine triphosphate production correlates to deoxycytidine kinase/cytosolic 5'-nucleotidaseIIexpression ratio in primary acute myeloid leukemia cells2009
- Author(s)
  T. Yamauchi, E. Negoro, S. Kishi, K. Takagi, A. Yoshida, Y. Urasaki, H. Iwasaki, T. Ueda
- Journal Title
  
  Biochem Pharmacol 77
  
  Pages: 1780-1786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591102
[Journal Article] Intracellular cytarabine triphosphate production correlates to deoxycytidine kinase/cytosolic 5'-nucleotidase II expression ratio in primary acute myeloid leukemia cells2009
- Author(s)
  T.Yamauchi, E.Negoro, S.Kishi, K.Takagi, A.Yoshida, Y.Urasaki, H.Iwasaki, T.Ueda
- Journal Title
  
  Biochemical Pharmacology 77
  
  Pages: 1780-1786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591102
[Journal Article] Intracellular cytarabine triphosphate production correlates to deoxycytidine kinase/cytosolic 5'-nucleotidase II expression ratio in primary acute myeloid leukemia cells2009
- Author(s)
  Yamauchi T, Negoro E, Kishi S, Takagi K, Yoshida A, Urasaki Y, Iwasaki H, Ueda T
- Journal Title
  
  Biochem Pharmacol
  
  Volume: 77(12) Pages: 1780-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591196
[Journal Article] GP7 induces internucleosomal DNA fragmentation independent of caspase activation and DNA fragmentation factor in NB4 cells.2007
- Author(s)
  Qi SN, Jing YX, Dong GX, Chen Y, Yoshida A, Ueda T.
- Journal Title
  
  Oncol Rep. 18(1)
  
  Pages: 273-277
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590986
[Journal Article] Combined low-dose cytarabine, melphalan and mitoxantrone for older patients with acute myeloid leukemia or high-risk myelodysplastic syndrome2007
- Author(s)
  T. Ymauchi, E. Negoro, H. Arai, S. Ikegaya, K. Takagi, H. Takemura, K. Inai, A. Yoshida, Y. Urasaki, H. Iwasaki, T. Ueda
- Journal Title
  
  Anticancer Res 27
  
  Pages: 2635-2639
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591102
[Journal Article] GP7 induces internucleosomal DNA fragmentation independent of caspase activation and DNA fragmentation factor in NB4 cells2007
- Author(s)
  Qi, SN, Sing, YX., Dong, GX., Chen, Y., Yoshida, A., Ueda, T
- Journal Title
  
  Oncol Rep 18(1)
  
  Pages: 273-277
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590986
[Journal Article] Inhibition of glutathione synthesis overcomes Bcl-2-mediated topoisomerase inhibitor resistance and induces nonapoptotic cell death viamitochondrial-independent pathway2006
- Author(s)
  Yoshida, A*., Takemura, H., Inoue, H., Miyashita, T., Ueda, T
- Journal Title
  
  Cancer Res 66
  
  Pages: 5772-5780
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590986
[Journal Article] Inhibition of glutathione synthesis overcomes Bcl-2-mediated topoisomerase inhibitor resistance and induces nonapoptotic cell death via mitochondrial-independent pathway.2006
- Author(s)
  Yoshida A^*, Takemura H, Inoue H, Miyashita T, Ueda T.
- Journal Title
  
  Cancer Res. 66
  
  Pages: 5772-5780
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590986
[Journal Article] Endonuclease activation and chromosomal DNA fragmentation during apoptosis in leukemia cells.2006
- Author(s)
  Yoshida A, Pommier Y, Ueda T.
- Journal Title
  
  Int J Hematol. 84
  
  Pages: 31-37
- NAID
  10020357669
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590986
[Journal Article] Endonuclease activation and chromosomal DNA fragmentation during apoptosis In leukemia cells2006
- Author(s)
  Yoshida, A., Pozmnier, Y., Ueda, T
- Journal Title
  
  Int J Hematol 84
  
  Pages: 31-37
- NAID
  10020357669
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590986
[Journal Article] L-carnitine inhibits apoptotic DNA fragmentation induced by a new spin-labeled derivative of podophyllotoxin via caspase-3 in Raji cells.2006
- Author(s)
  Qi SN, Zhang ZF, Wang ZY, Yoshida A, Ueda T.
- Journal Title
  
  Oncology Report 15(1)
  
  Pages: 119-122
- Data Source
  KAKENHI-PROJECT-17590986
[Journal Article] Inhibition of glutathione synthesis overcomes Bcl-2-mediated topoisomerase inhibitor resistance and induces nonapoptotic cell death via mitochondrial-independent pathway.2006
- Author(s)
  Yoshida A, Takemura H, et al.
- Journal Title
  
  Cancer Research 66(11):
  
  Pages: 5772-80
- Data Source
  KAKENHI-PROJECT-17590986
[Journal Article] 抗アポトーシス分子Survivinと白血病2005
- Author(s)
  吉田明, 上田孝典
- Journal Title
  
  血液フロンティア 15(5)
  
  Pages: 94-99
- Data Source
  KAKENHI-PROJECT-17590986
[Journal Article] Endonuclease activation and chromosomal DNA fragmentation during apoptosis in leukemia cells.2004
- Author(s)
  Yoshida A, Ueda T, et al.
- Journal Title
  
  Int J Hematol. 4(1):
  
  Pages: 31-7
- NAID
  10020357669
- Data Source
  KAKENHI-PROJECT-17590986
[Presentation] 難治性多発性骨髄腫に対する新規治療法開発2019
- Author(s)
  吉田　明
- Organizer
  第9回国際医療福祉大学学会学術大会
- Data Source
  KAKENHI-PROJECT-16K08410
[Presentation] ベネトクラックスとMcl-1阻害剤の併用は多発性骨髄腫に対して優れた細胞障害効果を発揮する。2018
- Author(s)
  吉田明
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08410
[Presentation] Prediction for poor mobilization of PBSC in patients with hematological malignancy.2016
- Author(s)
  Kana Oiwa, Shinji Kishi, Rena Matsumoto, Hikaru Tsukasaki, Miyuki Ookura, Akira Yoshida, Takanori Ueda, Takahiro Yamauchi
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K08410
[Presentation] Survivin inhibitor YM155 exerts potent cytotoxicity against quiescent (G0/G1) myeloma cells.2016
- Author(s)
  Miyuki Ookura, Shinji Kishi, Takahiro Yamauchi, Takanori Ueda, Akira Yoshida
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K08410
[Presentation] The indolocarbazole derivative Go6976 suppresses the growth of leukemia cells with FLT3 mutations2012
- Author(s)
  Yoshida, A, Zokumasu, k., Ueda T
- Organizer
  American Association for Cancer Research Annual meeting 2012
- Place of Presentation
  Chicago Illinois, USA
- Year and Date
  2012-04-02
- Data Source
  KAKENHI-PROJECT-21591196
[Presentation] The indolocarbazole, Go6976, suppresses the growth of leukemia cells with FLT3 mutations2011
- Author(s)
  Yoshida A, Zokumasu K, Ueda T
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-21591196
[Presentation] Marked Upregulations of Survivin and Aurora-B Kinase Are Associated with Disease Progression in the Myelodysplastic Syndromes2011
- Author(s)
  Yoshida, A. Zokumasu K., Yamauchi, T., Takagi, K., Kishi, S., Urasaki, Y., Tohyama, K., Ueda T.
- Organizer
  53rd American Society of Hematology Annual meeting
- Place of Presentation
  San Diego CA, USA
- Year and Date
  2011-12-12
- Data Source
  KAKENHI-PROJECT-21591196
[Presentation] Marked upregulation of Survivin and Aurora-B kinase are associated with disease progression in the Myelodysplastic Syndromes2011
- Author(s)
  Yoshida, A
- Organizer
  The 2nd Japanese Society of Hematology International Symposium 2011
- Place of Presentation
  長崎
- Year and Date
  2011-04-23
- Data Source
  KAKENHI-PROJECT-21591196
[Presentation] Yoshida, A.Zokumasu K., Yamauchi, T., Takagi, K., Kishi, S., Urasaki, Y., Tohyama, K., Ueda T. : Marked Upregulations of Survivin and Aurora-B Kinase Are Associated with Disease Progression in the Myelodysplastic Syndromes2011
- Author(s)
  Yoshida A, Ueda T
- Organizer
  53rd American Society of Hematology Annual meeting
- Place of Presentation
  San Diego CA, USA
- Year and Date
  2011-12-05
- Data Source
  KAKENHI-PROJECT-21591196
[Presentation] Potent cytotoxic activity of Go6976 in FLT3-driven leukemic cells.2010
- Author(s)
  Yoshida A, Ueda T.
- Organizer
  第72回日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21591196
[Presentation] Potent cytotoxic activity of Go6976 in FLT3-driven leukemic cells2010
- Author(s)
  Yoshida A, Ueda T
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-21591196
[Presentation] ハイリスクMDSではSurvivinの著明な高発現が検出される2009
- Author(s)
  吉田明,田中沙季,山内高弘,高木和貴,岸愼治,浦崎芳正,通山薫,上田孝典
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2009-10-12
- Data Source
  KAKENHI-PROJECT-21591196
[Presentation] 白血病細胞株における解毒酵素GSTM1の発現による抗腫瘍効果の検討2007
- Author(s)
  細野菜穂子, 岸慎治, 浦崎芳正, 吉田明, 上田孝典, 伊保澄子
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-12
- Data Source
  KAKENHI-PROJECT-19591102
[Presentation] 造血器悪性腫瘍細胞株におけるAra-C耐性機序の網羅的解析2007
- Author(s)
  根来英樹, 浦崎芳正, 岸慎治, 山内高弘, 河合泰一, 吉田明, 岩崎博道, 上田孝典
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-12
- Data Source
  KAKENHI-PROJECT-19591102
[Presentation] Unique resistance mechanism to dexamethasone by Glutathione S-transferase Ml involving p38 MAPK and NF-kB pathways, possible Prognostic role for childhood ALL2007
- Author(s)
  N. Hosono, S. Kishi, S. Iho, Y. Urasaki, A. Yoshida, H. Kurooka, Y. Yokota, T. Ueda
- Organizer
  The 49th ASH Annual Meeting
- Place of Presentation
  Atlanta
- Year and Date
  2007-12-08
- Data Source
  KAKENHI-PROJECT-19591102
[Presentation] 原発性アミロイドーシスに対するメルファラン大量療法を中心とした治療開発2007
- Author(s)
  河合泰一, 酒巻一平, 根来英樹, 大槻希美, 木下圭一, 岸慎治, 山内高弘, 浦崎芳正, 吉田明, 岩崎博道, 津谷寛, 上田孝典
- Organizer
  第69回日本血液学会・第49回日本臨床血液学会合同総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-12
- Data Source
  KAKENHI-PROJECT-19591102

1. UEDA Takanori (40160171)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
2. YAMAUCHI Takahiro (90291377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. KISHI Shinji (30334816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
4. 前川平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 八木秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yoshida Akira 吉田 明

吉田 明 ヨシダ アキラ

YOSHIDA Akira 吉田 明

吉田 朗 ヨシダ アキラ

Research Projects

Research Products

Co-Researchers

Molecular targeted therapy against leukemia stem cells via inhibition of anti-apoptotic proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of autophagy in follicular lymphoma cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Tailor-made therapy based on pharmacogenomic strategy for refractory leukemia due to multifactorial drug resistance

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Survivin-directed RNA interference is a potent suppressor of leukemia growthPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cloning of new endonuclease (AN34) involved in apoptosis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

抗腫瘍剤による白血病細胞のアポトーシスに関与するエンドヌクレアーゼの同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

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トポイソメラーゼ阻害剤による白血病細胞のアポトーシス誘発機構の解明Principal Investigator

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[Book] 白血病・リンパ腫・骨髄腫-今日の診断と治療.第4版2011

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[Book] 2.造血器腫瘍の治療.総論A化学療法剤.2011

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[Book] 分子標的治療5.ボルテゾミブ.2009

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[Journal Article] Bcl-2阻害剤ベネトクラクス(Venetoclax)の慢性リンパ性白血病および急性骨髄性白血病に対する優れた臨床効果2019

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[Journal Article] YM155 exerts potent cytotoxic activity against quiescent (G<sub>0</sub>/G<sub>1</sub>) multiple myeloma and bortezomib resistant cells <i>via</i> inhibition of survivin and Mcl-12017

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NAID

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[Journal Article] The combination of panobinostat with ponatinib synergistically overcomes imatinib-resistant CML cells.2016

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NAID

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[Journal Article] Marked upregulation of Survivin and Aurora-B kinase are associated with disease progression in the myelodysplastic syndromes2012

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Yoshida Akira 吉田明

吉田明ヨシダアキラ

YOSHIDA Akira 吉田明

吉田朗ヨシダアキラ