SHINTANI Yoshizumi 新谷良澄

… Alternative Names

新谷良澄シンタニヨシズミ

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Researcher Number	80261965
Affiliation (based on the past Project Information) *help	2009: 東京大学, 医学部附属病院, 講師 2008: 東京大学, 医学部・附属病院, 講師 2007: 東京大学, 医学部・附属病院, 助教 2002 – 2006: THE UNIVERSITY OF TOKYO, FACULTY OF MEDICINE, RESEARCH ASSOCIATE, 医学部附属病院, 助手 1995: 東京大学, 医学部(病), 助手
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator Biological Sciences / Gastroenterology / Gastroenterology
Keywords	Principal Investigator C型肝炎ウイルス / HCVコア蛋白質 / 糖尿病 / インシュリン抵抗性 / HCVコア蛋白 / 肝発癌 / 細胞周期 / コア蛋白 Except Principal Investigator トランスジェニックマウス / ミトコンドリア … More / C型肝炎ウイルス / core protein / ROS / コア蛋白 / 酸化ストレス / 肝発癌 / HCV / transgenic mouse / hepatocarcinogenesis / hepatitis C virus / 脂肪化 / インスリン抵抗性 / 脂質代謝 / 細胞内シグナル伝達 / nuclear receptor / Lipid metabolism / Insulin resistance / 核内レセプター / electron transfer system / proteomics / mitochondrion / 肝発がん / 電子伝達系 / プロテオミクス / alcohol / cytotoxic lymphocytes / steatosis / inflammation / transgenic mice / hepatocarcinogeneis / アルコール / 細胞障害性リンパ球 / 炎症 / 肝癌 / insulin resistance / retinoid X receptor / intracellular signal transduction / oxidative stress / アポリポ蛋白 / DNA障害 / β酸化 / AP-1 / MAPK / 肝細胞癌 / レチノイドX受容体 / 肺発がん / C型肝炎 / 予防薬 / マウスモデル Less

C型肝炎ウイルスによる肝発癌機構の解明:細胞内標的の探索と治療法の開発
- Principal Investigator
  
  小池和彦
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
C型肝炎ウイルスによる肝発癌機構の解明
- Principal Investigator
  
  小池和彦
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
C型肝炎ウイルスによる肝発癌機構の解明
- Principal Investigator
  
  KOIKE Kazuhiko
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Functional abnormality in the mitochondria and pathogenesis of chronic hepatitis C: relation to hepatocellular carcinoma
- Principal Investigator
  
  KOIKE Kazuhiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Regulation of hepatocarcinogenesis by using antagonists to retinoid X receptor alpha RXRalpha.
- Principal Investigator
  
  MORIYA Kyoji
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
C型肝炎における糖尿病多発機序の解明:ウイルス蛋白によるインシュリン抵抗性の発生Principal Investigator
- Principal Investigator
  
  新谷良澄
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Study on the mechanism of hepatocarcinogenesis in hepatitis C viral infection
- Principal Investigator
  
  KOIKE Kazuhiko
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
THE ROLES OF HEPATITIS C VIRUS AND INFLAMMATION IN THE PATHOGENESIS OF HEPATOCELLULAR CARCINOMA
- Principal Investigator
  
  KOIKE Kazuhiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  THE UNIVERSITY OF TOKYO
C型肝炎ウイルス蛋白の細胞周期進行作用とその肝発癌における役割Principal Investigator
- Principal Investigator
  
  新谷良澄
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo

All 2005 2004 2003 2002 2001 2000

All Journal Article

[Journal Article] Hepatitis C Virus Core Protein Exerts an Inhibitory Effect on Suppressor of Cytokine Signaling (SOCS)-1 Gene Expression.2005
- Author(s)
  Miyoshi H, Fujie H, Shintani Y, Tsutsumi T, Shinzawa S, Makuuchi M, Kokudo N, Matsuura Y, Suzuki T, Miyamura T, Moriya K, Koike K.
- Journal Title
  
  J Hepatol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Hepatitis C virus and diabetes : direct involvement of the virus in the development of insulin resistance.2004
- Author(s)
  Shintani Y, et al.
- Journal Title
  
  Gastroenterology 126
  
  Pages: 840-848
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390226
[Journal Article] Hepatitis C virus infection and diabetes : direct involvement of the virus in the develonment of insulin resistance2004
- Author(s)
  Shintani Y, Fujie H, Miyoshi H, Tsutsumi T, Tsukamoto K, Kimura S, Moriya K, Koike K.
- Journal Title
  
  Gastroenterology 126(3)
  
  Pages: 840-848
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Prevalence of measles, rubella, mumps, and varicella antibodies among healthcare workers in Japan2004
- Author(s)
  Hatakeyama S, Moriya K, Itoyama S, Nukui Y, Uchida M, Shintani Y, Morisawa Y, Kimura S.
- Journal Title
  
  Infection Control and Hospital Epidemiology 25(7)
  
  Pages: 591-594
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Methylation status of suppressor of cytokine sigasling-1 gene in hepatocellular carcinoma2004
- Author(s)
  Miyoshi H, Fujie H, Moriya K, Shintani Y, Tsutsumi T, Makuuchi M, Kimura S, Koike K.
- Journal Title
  
  J Gastroenterol 39(6)
  
  Pages: 563-569
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Methylation status of suppressor of cytokine signaling-1 gene in hepatocellular carcinoma.2004
- Author(s)
  Miyoshi H, Fujie H, Moriya K, Shintani Y, Tsutsumi T, Makuuchi M, Kimura S, Koike K.
- Journal Title
  
  Journal of Gastroenterology 39(6)
  
  Pages: 563-569
- NAID
  10013296326
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Hepatitis C and Diabetes Mellitus : what is the metabolic pathway?2004
- Author(s)
  Koike K, Fujie H, Shintani Y, Miyoshi H, Mariya K.
- Journal Title
  
  Gastroenterology 127
  
  Pages: 1280-1281
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390226
[Journal Article] Methylation status of suppressor of cytokine signaling-1 gene in hepatocellular carcinoma.2004
- Author(s)
  Miyoshi H, Fujie H, Mariya K, Shintani Y, Tsutsumi T, Makuuchi M, Kimura S, Koike K.
- Journal Title
  
  J Gastroenterol 39
  
  Pages: 563-569
- NAID
  10013296326
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390226
[Journal Article] Hepatitis C virus and diabetes : direct involvement of the virus in the development of insulin resistance.2004
- Author(s)
  Shintani Y
- Journal Title
  
  Gastroenterology 126
  
  Pages: 840-848
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Prevalence of measles, rubella, mumps, and varicella antibodies among healthcare workers in Japan2004
- Author(s)
  Hatakeyama S, Moriya K, Itoyama S, Nukui Y, Uchida M, Shintani Y, Morisawa Y, Kimura S.
- Journal Title
  
  Infect Control Hosp Epidemiol 25(7)
  
  Pages: 591-594
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Hepatitis C virus infection and diabetes : direct involvement of the virus in the development of insulin resistance.2004
- Author(s)
  Shintani Y, Fujie H, Miyoshi H, Tsutsumi T, Tsukamoto K, Kimura S, Moriya K, Koike K.
- Journal Title
  
  Gastraenterolagy. 126(3)
  
  Pages: 840-848
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Hepatitis C virus and diabetes : direct involvement of the virus in the development of insulin resistance.2004
- Author(s)
  Shintani Y, Fujie H, Miyoshi H, Tsutsumi T, Kimura S, Moriya K, Koike K.
- Journal Title
  
  Gastroenterology 126
  
  Pages: 840-848
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Prevalence of measles, rubella, mumps, and varicella antibodies among healthcare workers in Japan. International meeting2004
- Author(s)
  Hatakeyama S, Moriya K, Itoyama S, Nukui Y, Uchida M, Shintani Y, Morisawa Y, Kimura S
- Journal Title
  
  Infect Control Hosp Epidemiol. 25(7)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Hepatitis C virus infection and diabetes : direct involvement of the virus in the development of insulin resistance.2004
- Author(s)
  Shintani Y, Fujie H, Miyoshi H, Tsutsumi T, Tsukamoto K, Kimura S, Moriya K, Koike K.
- Journal Title
  
  Gastroenterology 126(3)
  
  Pages: 840-848
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Hepatitis C virus and diabetes : direct involvement of the virus in the development of insulin resistance.2004
- Author(s)
  Shintani Y, Fujie H, Miyoshi H, Tsutsumi T, Kimura S, Mariya K, Koike K.
- Journal Title
  
  Gastroenterology 126
  
  Pages: 840-848
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390226
[Journal Article] Methylation status of suppressor of cytokine signaling-1 gene in hepatocellular carcinoma.2004
- Author(s)
  Miyoshi H, Fujie H, Moriya K, Shintani Y, Tsutsumi T, Makuuchi M, Kimura S, Koike K.
- Journal Title
  
  J Gastroenterol. 39(6)
  
  Pages: 563-569
- NAID
  10013296326
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Hepatitis C virus and diabetes : direct involvement of the virus in the development of insulin resistance.2004
- Author(s)
  Shintani Y, et al.
- Journal Title
  
  Gastroenterology 126
  
  Pages: 840-848
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Serum lipid profile of patients with genotype 1b hepatitis C viral infection in Japan.2003
- Author(s)
  Moriya K, Shintani Y, Fujie H, Miyoshi H, Tsutsumi T, Yotsuyanagi H, Iino S, Kimura S, Koike K.
- Journal Title
  
  Hepatol Res. 25(4)
  
  Pages: 371-376
- NAID
  50000829733
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Hepatitis C virus core protein activates ERK and p38 MAPK in cooperation with ethanol in transgenic mice.2003
- Author(s)
  Tsutsumi T, Suzuki T, Moriya K, Shintani Y, Fujie H, Miyoshi H, Matsuura Y, Koike K, Miyamura T.
- Journal Title
  
  Hepatology 38(4)
  
  Pages: 820-828
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Serum lipid profile of patients with genotype 1b hepatitis C viral infection in Japan2003
- Author(s)
  Moriya K, Shintani Y, Fujie H, Miyoshi H, Tsutsumi T, Yotsuyanagi H, Iino S, Kimura S, Koike K.
- Journal Title
  
  Hepatology Research 25(4)
  
  Pages: 371-376
- NAID
  50000829733
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Hepatitis C virus core protein activates ERK and p38 MAPK in cooperation with ethanol in transgenic mice.2003
- Author(s)
  Tsutsumi T, Suzuki T, Moriya K, Shintani Y, Fujie H, Miyoshi H, Matsuura Y, Koike K, Miyamura T.
- Journal Title
  
  Hepatology. 88(4)
  
  Pages: 820-828
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590624
[Journal Article] Miyamura T. Hepatitis C virus core protein activates ERK and p38 MAPK in cooperation with ethanol in transgenic mice.2002
- Author(s)
  Tsutsumi T, Suzuki T, Moriya K, Shintani Y, Fujie H, Miyoshi H, Matsuura Y, Koike K
- Journal Title
  
  Hepatology 38
  
  Pages: 820-828
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Miyamura T. Intrahepatic cytokine expression and AP-1 activation in mice transgenic for hepatitis C virus core protein.2002
- Author(s)
  Tsutsumi T, Suzuki T, Moriya K, Yotsuyanagi H, Shintani Y, Fujie H, Matsuura Y, Kimura S, Koike K
- Journal Title
  
  Virology 304
  
  Pages: 415-424
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Increase in the concentration of carbon 18 monounsaturated fatty acids in the liver with hepatitis C : analysis in transgenic mice and humans.2001
- Author(s)
  Moriya K, Todoroki T, Tsutsumi T, Fujie H, Shintani Y, Miyoshi H, Ishibashi K, Takayama T, Makuuchi M, Watanabe K, Miyamura T, Kimura S, Koike K.
- Journal Title
  
  Biophys Biochem Res Commun 281
  
  Pages: 1207-1212
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Oxidative stress in the absence of inflammation in a mouse model for hepatitis C virus-associated hepatocellular carcinogenesis.2001
- Author(s)
  Moriya K, Nakagawa K, Santa T, Shintani Y, Fujie H, Miyoshi H, Tsutsumi T, Miyazawa T, Ishibashi K, Horie T, Imai K, Miyamura T, Kimura S, Koike K.
- Journal Title
  
  Cancer Res 61
  
  Pages: 4365-4370
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Frequent β-catenin aberration in human hepatocellular carcinoma.2001
- Author(s)
  Fujie H, Moriya K, Shintani Y, Tsutsumi T, Takayama T, Makuuchi M, Kimura S, Koike K.
- Journal Title
  
  Hepatol Res 20
  
  Pages: 39-51
- NAID
  10009899927
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214018
[Journal Article] Virological analysis of non-B, non-C hepatocellular carcinoma in Japan : frequent involvement of hepatitis B virus2000
- Author(s)
  Yotsuyanagi H, Shintani Y, Moriya K, Fujie H, Tsutsumi T, Kato T, Nishioka K, Takayama T, Makuuchi M, Iino S, Kimura S, Koike K.
- Journal Title
  
  J Infect Dis 181
  
  Pages: 1920-1928
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214018

1. KOIKE Kazuhiko (80240703)

# of Collaborated Projects: 8 results

# of Collaborated Products: 21 results
2. MORIYA Kyoji (00272550)

# of Collaborated Projects: 5 results

# of Collaborated Products: 21 results
3. 三好秀征 (00401042)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
4. FUJIE Hajime (90332577)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
5. 四柳宏 (30251234)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TSUTSUMI Takeya

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results

SHINTANI Yoshizumi 新谷 良澄

新谷 良澄 シンタニ ヨシズミ

Research Projects

Research Products

Co-Researchers

C型肝炎ウイルスによる肝発癌機構の解明:細胞内標的の探索と治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

C型肝炎ウイルスによる肝発癌機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

C型肝炎ウイルスによる肝発癌機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional abnormality in the mitochondria and pathogenesis of chronic hepatitis C: relation to hepatocellular carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of hepatocarcinogenesis by using antagonists to retinoid X receptor alpha RXRalpha.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

C型肝炎における糖尿病多発機序の解明:ウイルス蛋白によるインシュリン抵抗性の発生Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the mechanism of hepatocarcinogenesis in hepatitis C viral infection

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

THE ROLES OF HEPATITIS C VIRUS AND INFLAMMATION IN THE PATHOGENESIS OF HEPATOCELLULAR CARCINOMA

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

C型肝炎ウイルス蛋白の細胞周期進行作用とその肝発癌における役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Hepatitis C Virus Core Protein Exerts an Inhibitory Effect on Suppressor of Cytokine Signaling (SOCS)-1 Gene Expression.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Hepatitis C virus and diabetes : direct involvement of the virus in the development of insulin resistance.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Hepatitis C virus infection and diabetes : direct involvement of the virus in the develonment of insulin resistance2004

Author(s)

Journal Title

Data Source

[Journal Article] Prevalence of measles, rubella, mumps, and varicella antibodies among healthcare workers in Japan2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Methylation status of suppressor of cytokine sigasling-1 gene in hepatocellular carcinoma2004

Author(s)

SHINTANI Yoshizumi 新谷良澄

新谷良澄シンタニヨシズミ