AKIYAMA Yosimitsu 秋山好光

… Alternative Names

秋山好光アキヤマヨシミツ

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Researcher Number	80262187
Other IDs
Affiliation (Current)	2025: 東京科学大学, 大学院医歯学総合研究科, 講師
Affiliation (based on the past Project Information) *help	2015 – 2024: 東京医科歯科大学, 大学院医歯学総合研究科, 講師 2012 – 2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 講師 2007 – 2011: Tokyo Medical and Dental University, Department of Molecular Oncology, lecturer 2009: Tokyo Medical and Dental University, 医歯学総合研究科, 講師 2006: Tokyo Medical and Dental University, Department of Molecular Oncology, Lecturer, 大学院医歯学総合研究科, 講師 … More 2003 – 2005: Tokyo Medical and Dental University, Department of Molecular Oncology, lecturer, 大学院・医歯学総合研究科, 講師 2000: 東京医科歯科大学, 大学院・医歯学総合研究科, 助手 1996 – 1999: 東京医科歯科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Human pathology / Basic Section 50020:Tumor diagnostics and therapeutics-related / Human pathology Except Principal Investigator Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Hygiene / Biological Sciences / Basic Section 55020:Digestive surgery-related / General surgery / Digestive surgery / Hygiene
Keywords	Principal Investigator メチル化 / 胃がん / エピジェネティクス / 大腸癌 / エピゲノム / ヒストン修飾 / CpGアイランド / 3p21 / 難治性消化器癌 / CpG … More / ヒストン / 分子病理 / 胃癌 / カルシウムチャンネル / TGF-βII型レセプター / 大腸腺腫内癌 / HNPCC / 腫瘍微小免疫環境 / 難治性がん / 腫瘍免疫環境 / 消化器癌 / 腫瘍免疫 / H3K9me3 / SETDB2 / SETDB1 / ヒストンメチル化 / 難治性癌 / クロマチン免疫沈降法 / SETドメイン / prognostic marker / methylation / gastric cancer / calcium channel / MSP / カルシウムチャネル / 予後 / 転写因子 / 組織多様性 / 組織内多様性 / プロモーター領域 / マイクロRNA / メチル化特異的PCR法 / メチル化特異的PCR / GATA5 / GATA4 / GATA転写因子 / CpG island / 未分化型がん / 大腸がん / 18q21 / LOH / p53 / APC / de novo癌 / Smad3 / TGF-β / (A)_<10>領域 / RER … More Except Principal Investigator ゲノム編集 / SOX2 / CDX2 / メチル化 / 胃がん / 難治性がん / 癌 / 生活習慣 / 多様性 / 分子サブタイプ / gastric cancer / 血球DNA / PDX1 / MUC6 / BMP-2 / 免疫疲弊 / CAR-T / RNA編集 / 免疫治療 / ゲノム医療 / ヒストン修飾 / 外科 / 転移 / トランスレーショナルリサーチ / 幹細胞 / 炎症 / Hath-1 / Notch / 分化 / 緑茶 / DNAメチル化 / エピジェネティクス / 転写因子 / 転写調節 / ホメオプロテイン / カルシウムチャンネル / 代謝異常 / 腫瘍微小環境 / シングルセル解析 / 多重ゲノム編集 / 複合免疫療法 / 膵癌 / 腫瘍関連線維芽細胞(CAF) / 免疫逃避 / 肝転移 / 播種転移 / 樹状細胞 / 細胞外基質 / エピゲノム制御 / 免疫抑制因子 / 同系統移植モデル / 免疫チェックポイント / 免疫抵抗性獲得 / 樹状細胞活性化 / オルガノイド / がん幹細胞 / サブタイプ / レンチウイルス / プレシジョンメディシン / 分子サブタイプ分類 / エキソンスキッピング / 高頻度変異 / クロマチンリモデリング / 腫瘍変異負荷 / DNA損傷 / ゲノム / 遺伝子 / クロマチン再構築 / クロマチン動的変動 / ゲノム編集技術 / シグナル伝達 / 再生医学 / がん予防 / 治療標的 / risk evaluation / biomarker / smoking / life style / DNA Methylation / エビジェネティクス / リスク評価 / 生体指標 / 喫煙 / apoptosis / Mucin / differentiation / 胆嚢がん / Sp1 / NFκB / DNMT3A / アポトーシス / ムチン / transcription / diet / methylation / homeoprotein / 腸上皮化生 / DNA / エストジェン受容体 / カルシュウムチャンネル遺伝子 / トランスジェニックマウス / ノックアウト / IQGAP2 / NOTCH / E-カドヘリン / マウスモデル / マイクロRNA / 実験動物モデル / hMLH1遺伝子 / 大腸がん / SOX2遺伝子 / 二次原発がん / PDX1遺伝子 / CDX2遺伝子 / 発生リスク / 生活習慣要因 / DNAメチルトランスフェラーゼ / エピジェネティック疫学 Less

Analysis of tumor microenvironmental alterations in refractory cancer based on histone modification changes and development of novel therapeutic strategiesPrincipal Investigator
- Principal Investigator
  
  秋山好光
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Tokyo Medical and Dental University
Development of advanced therapy for refractory cancer based on elucidation of in vivo diversity mechanisms
- Principal Investigator
  
  田中真二
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tokyo Medical and Dental University
In vivo comprehensive genome editing analysis to elucidate the mechanisms of cancer refractoriness for development of novel therapies
- Principal Investigator
  
  Tanaka Shinji
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Tokyo Medical and Dental University
Application of multiplex genome editing technology to the development of CAR-T therapy for refractory cancer subtypes
- Principal Investigator
  
  Tanaka Shinji
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Tokyo Medical and Dental University
Envolvement of abnormal of SETDB-related histone modification enzyme and tumor immune environment in gastrointestinal cancerPrincipal Investigator
- Principal Investigator
  
  Akiyama Yoshimitsu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Tokyo Medical and Dental University
Clarification of diversity mechanisms for innovation of refractory cancer treatment
- Principal Investigator
  
  Tanaka Shinji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Tokyo Medical and Dental University
Innovation of genome editing technology as the basis to develop molecular subtype panels of intractable cancer
- Principal Investigator
  
  Tanaka Shinji
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Tokyo Medical and Dental University
Develoment of advanced therapy targeting tumor heterogeneity in refractory cancers
- Principal Investigator
  
  TANAKA Shinji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  Tokyo Medical and Dental University
Molecular pathology of SET-related histone methyltransferase in refractory cancerPrincipal Investigator
- Principal Investigator
  
  Akiyama Yoshimitsu
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Medical and Dental University
Innovative treatment of refractory digestive cancers based on the stemness visualization system
- Principal Investigator
  
  Tanaka Shinji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Medical and Dental University
Epigenetic alterations and tumor heterogeneity in gastric cancersPrincipal Investigator
- Principal Investigator
  
  AKIYAMA Yoshimitsu
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Medical and Dental University
Clinicopathological significance and epigenetic alterations of miRNAs in gastric cancerPrincipal Investigator
- Principal Investigator
  
  AKIYAMA Yoshimitsu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Medical and Dental University
Epigenetic epidemiology of gastric cancer
- Principal Investigator
  
  YUASA Yasuhito
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Tokyo Medical and Dental University
Epigenetic alterations of GATA transcription factor genes in gastric cancersPrincipal Investigator
- Principal Investigator
  
  AKIYOSHI Yoshimitsu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Medical and Dental University
Establishment of epigenetic epidemiology
- Principal Investigator
  
  YUASA Yasuhito
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Tokyo Medical and Dental University
Relationship between surrogate markers including DNA methylation and lifestyle factors in gastric carcinogenesis
- Principal Investigator
  
  YUASA Yasuhito
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Methylation analysis of calcium channel-related genes in gastric cancerPrincipal Investigator
- Principal Investigator
  
  AKIYAMA Yoshimitsu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Medical and Dental University
Inflammation-caused abnormalities in gastric differentiation and molecular epidemiologic analysis of gastric cancer
- Principal Investigator
  
  YUASA Yasuhito
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Tokyo Medical and Dental University
消化器がんにおけるがん関連遺伝子の異常メチル化と臨床病理学的諸性状との関係Principal Investigator
- Principal Investigator
  
  秋山好光
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Medical and Dental University
Aberrant differentiation of the gastric epithelium after inflammation and molecular epidemiological analysis of gastric cancers
- Principal Investigator
  
  YUASA Yasuhito
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Tokyo Medical and Dental University
宿主・環境要因に着目した消化管がんの二次原発がん発生リスクに関する研究
- Principal Investigator
  
  YUASA Yasuhito
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
平坦陥凹型大腸癌における染色体18q21内の癌関連遺伝子解析とその発癌機構の解明Principal Investigator
- Principal Investigator
  
  秋山好光
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tokyo Medical and Dental University
発癌におけるTGF-βシグナル伝達系関連遺伝子の役割Principal Investigator
- Principal Investigator
  
  秋山好光
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Medical and Dental University
TGF-βレセプターの発癌における役割Principal Investigator
- Principal Investigator
  
  秋山好光
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Medical and Dental University

[Book] 疾患・病態検査・診断法の開発2017
- Author(s)
  秋山好光（分担）
- Total Pages
  489
- Publisher
  技術情報協会
- ISBN
  9784861046742
- Data Source
  KAKENHI-PROJECT-16K08647
[Book] 胃がん.がん生物学イラストレイテッド2011
- Author(s)
  湯浅保仁、秋山好光
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21590396
[Book] エピジェネティクスと電気泳動.改訂版-そこが知りたい電気泳動.大藤道衛編集2011
- Author(s)
  秋山好光
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21590396
[Book] バイオ実験誰もがつまずく失敗&ナットク解決法2008
- Author(s)
  秋山好光(共著)
- Total Pages
  236
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-19590340
[Journal Article] Loss of SFXN1 mitigates lipotoxicity and predicts poor outcome in non-viral hepatocellular carcinoma2023
- Author(s)
  Yagi K, Shimada S, Akiyama Y, Hatano M, Asano D, Ishikawa Y, Ueda H, Watanabe S, Akahoshi K, Ono H, Tanabe M, Tanaka S.
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 9449-9449
- DOI
  10.1038/s41598-023-36660-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19554, KAKENHI-PROJECT-23K27670
[Journal Article] RTP4 silencing provokes tumor-intrinsic resistance to immune checkpoint blockade in colorectal cancer2023
- Author(s)
  Yamamoto Yudai、Shimada Shu、Akiyama Yoshimitsu、Tsukihara Shu、Sugimoto Raizo、Kabashima Ayano、Tokunaga Masanori、Kinugasa Yusuke、Kawakami Yutaka、Tanaka Shinji
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: ND Issue: 6 Pages: 1-14
- DOI
  10.1007/s00535-023-01969-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03526, KAKENHI-PROJECT-20H03534, KAKENHI-PROJECT-22K19554, KAKENHI-PROJECT-23K27670
[Journal Article] Loss of KDM6B epigenetically confers resistance to lipotoxicity in nonalcoholic fatty liver disease?related HCC2023
- Author(s)
  Hatano M, Akiyama Y, Shimada S, Yagi K, Akahoshi K, Itoh M, Tanabe M, Ogawa Y, Tanaka S.
- Journal Title
  
  Hepatology Communications
  
  Volume: 7 Issue: 10
- DOI
  10.1097/hc9.0000000000000277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19554, KAKENHI-PROJECT-23K27670
[Journal Article] RRM1 is mediated by histone acetylation through gemcitabine resistance and contributes to invasiveness and ECM remodeling in pancreatic cancer2023
- Author(s)
  Ono Hiroaki、Murase Yoshiki、Yamashita Hironari、Kato Tomotaka、Asano Daisuke、Ishikawa Yoshiya、Watanabe Shuichi、Ueda Hiroki、Akahoshi Keiichi、Ogawa Kosuke、Kudo Atsushi、Akiyama Yoshimitsu、Tanaka Shinji、Tanabe Minoru
- Journal Title
  
  International Journal of Oncology
  
  Volume: 62 Issue: 4 Pages: 51-51
- DOI
  10.3892/ijo.2023.5499
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08769, KAKENHI-PROJECT-21K08793, KAKENHI-PROJECT-22K08708, KAKENHI-PROJECT-22K19554, KAKENHI-PROJECT-23K27670
[Journal Article] cGAS-STING signaling encourages immune cell overcoming of fibroblast barricades in pancreatic cancer2022
- Author(s)
  Kabashima A, Matsuo Y, Ito S, Akiyama Y, Ishii T, Shimada S, Masamune A, Tanabe M, Tanaka S
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 10466-10466
- DOI
  10.1038/s41598-022-14297-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19554, KAKENHI-PROJECT-20K17606
[Journal Article] Identification of a novel target of <scp>SETD1A</scp> histone methyltransferase and the clinical significance in pancreatic?cancer2022
- Author(s)
  Ishii Takeshi、Akiyama Yoshimitsu、Shimada Shu、Kabashima Ayano、Asano Daisuke、Watanabe Shuichi、Ishikawa Yoshiya、Ueda Hiroki、Akahoshi Keiichi、Ogawa Kosuke、Ono Hiroaki、Kudo Atsushi、Tanabe Minoru、Tanaka Shinji
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 2 Pages: 463-476
- DOI
  10.1111/cas.15615
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08708, KAKENHI-PROJECT-22K19554, KAKENHI-PROJECT-20H03526
[Journal Article] C646 inhibits G2/M cell cycle-related proteins and potentiates anti-tumor effects in pancreatic cancer.2021
- Author(s)
  Ono H, Kato T, Murase Y, Nakamura Y, Ishikawa Y, Watanabe S, Akahoshi K, Ogura T, Ogawa K, Daisuke Ban, Kudo A, Akiyama Y, Tanaka S, Ito H, Tanabe M.
- Journal Title
  
  Scientific Reports, in press
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21627
[Journal Article] C646 inhibits G2/M cell cycle-related proteins and potentiates anti-tumoreffects in pancreatic cancer2021
- Author(s)
  Hiroaki Ono, Tomotaka Kato, Yoshiki Murase, Yutaro Nakamura, Yoshiya Ishikawa, Shuichi Watanabe, Keiichi Akahoshi, Toshiro Ogura, Kosuke Ogawa, Daisuke Ban, Atsushi Kudo, Yoshimitsu Akiyama, Shinji Tanaka, Hiromichi Ito, Minoru Tanabe
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 10078-10078
- DOI
  10.1038/s41598-021-89530-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06773, KAKENHI-PROJECT-20K21627, KAKENHI-PROJECT-19H01055, KAKENHI-PROJECT-21K08769, KAKENHI-PROJECT-21K08793
[Journal Article] Molecular and immunological paradigms of hepatocellular carcinoma: Special reference to therapeutic approaches2021
- Author(s)
  Kabashima A, Shimada S, Shimokawa M, Akiyama Y, Tanaka S.
- Journal Title
  
  Journal of Hepato-Biliary-Pancreatic Sciences
  
  Volume: 28 Issue: 1 Pages: 62-75
- DOI
  10.1002/jhbp.874
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21627, KAKENHI-PROJECT-19H01055, KAKENHI-PROJECT-20H03526, KAKENHI-PROJECT-20K17606
[Journal Article] C646 inhibits G2/M cell cycle-related proteins and potentiates anti-tumor effects in pancreatic cancer.2021
- Author(s)
  Ono H, Kato T, Murase Y, Nakamura Y, Ishikawa Y, Watanabe S, Akahoshi K, Ogura T, Ogawa K, Daisuke Ban, Kudo A, Akiyama Y, Tanaka S, Ito H, Tanabe M.
- Journal Title
  
  Scientific Reports, in press
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H01055
[Journal Article] Intrinsic activation of β-catenin signaling by CRISPR/Cas9-mediated exon skipping contributes to immune evasion in hepatocellular carcinoma2021
- Author(s)
  Akasu M, Shimada S, Kabashima A, Akiyama Y, Shimokawa M, Akahoshi K, Kudo A, Yamaoka S, Tanabe M, Tanaka S.
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 16732-16732
- DOI
  10.1038/s41598-021-96167-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21627, KAKENHI-PROJECT-19K18141, KAKENHI-PROJECT-19H01055, KAKENHI-PROJECT-20H03526, KAKENHI-PROJECT-21K16415, KAKENHI-PROJECT-20K17606
[Journal Article] Loss of ARID1A induces a stemness gene ALDH1A1 expression with histone acetylation in the malignant subtype of cholangiocarcinoma.2020
- Author(s)
  Yoshino J, Akiyama Y, Shimada S, Ogura T, Ogawa K, Ono H, Mitsunori Y, Ban D, Kudo A, Yamaoka S, Tanabe M, Tanaka S.
- Journal Title
  
  Carcinogenesis
  
  Volume: in press Issue: 6 Pages: 0000-0000
- DOI
  10.1093/carcin/bgz179
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H01055, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-18K19575, KAKENHI-PROJECT-20K21627, KAKENHI-PROJECT-20H03526
[Journal Article] ヒストン修飾2020
- Author(s)
  秋山好光
- Journal Title
  
  週刊医学のあゆみ
  
  Volume: 272 Pages: 10-16
- Data Source
  KAKENHI-PROJECT-16K08647
[Journal Article] A subset of diffuse-type gastric cancer is susceptible to mTOR inhibitors and checkpoint inhibitors2019
- Author(s)
  Fukamachi H、Kim SK、Koh J、Lee HS、Sasaki Y、Yamashita K、Nishikawaji T、Shimada S、Akiyama Y、Byeon SJ、Bae DH、Okuno K、Nakagawa M、Tanioka T、Inokuchi M、Kawachi H、Tsuchiya K、Kojima K、Tokino Takashi、Eishi Y、Kim YS、Kim WH、Yuasa Y、Tanaka S
- Journal Title
  
  Journal of Experimental & Clinical Cancer Research
  
  Volume: 38 Issue: 1 Pages: 127-127
- DOI
  10.1186/s13046-019-1121-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-18K19575, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-15K06832, KAKENHI-PROJECT-16H06279
[Journal Article] Asymmetric dimethylation at histone H3 arginine 2 by PRMT6 in gastric cancer progression.2019
- Author(s)
  Okuno K, Akiyama Y, Shimada S, Nakagawa M, Tanioka T, Inokuchi M, Yamaoka S, Kojima K, Tanaka S.
- Journal Title
  
  Carcinogenesis
  
  Volume: 40 Issue: 1 Pages: 15-26
- DOI
  10.1093/carcin/bgy147
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-18K19575, KAKENHI-PROJECT-16H02670
[Journal Article] 膵神経内分泌腫瘍におけるDAXX/ATRX異常とクロマチン修飾変化.2019
- Author(s)
  上田浩樹、秋山好光、田中真二.
- Journal Title
  
  肝胆膵
  
  Volume: 78 Pages: 39-46
- Data Source
  KAKENHI-PROJECT-16K08647
[Journal Article] Comprehensive molecular characterization of liver cancer and inheritance of the phenotypic traits during tumor recurrence.2019
- Author(s)
  Shimada S, Mogushi K, Akiyama Y, Furuyama T, Watanabe S, Ogura T, Ogawa K, Ono H, Mitsunori Y, Ban D, Kudo A, Arii S, Tanabe M, Wands JR, Tanaka S.
- Journal Title
  
  EBioMedicine
  
  Volume: 40 Pages: 457-470
- DOI
  10.1016/j.ebiom.2018.12.058
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-17K10689, KAKENHI-PROJECT-18K06198, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-18K19575, KAKENHI-PROJECT-16H02670
[Journal Article] Loss of KDM6A characterizes a poor prognostic subtype of human pancreatic cancer and potentiates HDAC inhibitor lethality2019
- Author(s)
  Watanabe S, Shimada S, Akiyama Y, Ishikawa Y, Ogura T, Ogawa K, Ono H, Mitsunori Y, Ban D, Kudo A, Yamaoka S, Tanabe M, Tanaka S.
- Journal Title
  
  International Journal of Cancer
  
  Volume: - Issue: 1 Pages: 192-205
- DOI
  10.1002/ijc.32072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19575, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-19H01055, KAKENHI-PROJECT-17K10689
[Journal Article] Upregulation of cancer-associated gene expression in activated fibroblasts in a mouse model of non-alcoholic steatohepatitis2019
- Author(s)
  Asakawa M, Itoh M, Suganami T, Sakai T, Kanai S, Shirakawa I, Yuan X, Hatayama T, Shimada S, Akiyama Y, Fujiu K, Inagaki Y, Manabe I, Yamaoka S, Yamada T, Tanaka S, Ogawa Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 9 Issue: 1 Pages: 19601-19601
- DOI
  10.1038/s41598-019-56039-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07143, KAKENHI-PROJECT-19K07475, KAKENHI-PROJECT-19K22627, KAKENHI-PUBLICLY-18H05039, KAKENHI-PROJECT-19H01054, KAKENHI-PROJECT-19H01055, KAKENHI-PROJECT-17H04166, KAKENHI-PROJECT-18H02859, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-17K01840, KAKENHI-PROJECT-18K19575
[Journal Article] Tumor suppressor functions of DAXX through histone H3.3/H3K9me3 pathway in pancreatic NETs.2018
- Author(s)
  Ueda H, Akiyama Y, Shimada S, Mogushi K, Serizawa M, Matsumura S, Mitsunori Y, Aihara A, Ban D, Ochiai T, Kudo A, Tanabe M, Tanaka S.
- Journal Title
  
  Endocr Relat Cancer
  
  Volume: 25(6) Issue: 6 Pages: 619-631
- DOI
  10.1530/erc-17-0328
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10653, KAKENHI-PROJECT-17K10689, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-18K19575, KAKENHI-PROJECT-15H04926
[Journal Article] Fatty Acid Binding Protein 4 (FABP4) Overexpression in Intratumoral Hepatic Stellate Cells within Hepatocellular Carcinoma with Metabolic Risk Factors2018
- Author(s)
  Chiyonobu Norimichi、Shimada Shu、Akiyama Yoshimitsu、Mogushi Kaoru、Itoh Michiko、Akahoshi Keiichi、Matsumura Satoshi、Ogawa Kosuke、Ono Hiroaki、Mitsunori Yusuke、Ban Daisuke、Kudo Atsushi、Arii Shigeki、Suganami Takayoshi、Yamaoka Shoji、Ogawa Yoshihiro、Tanabe Minoru、Tanaka Shinji
- Journal Title
  
  Am. J. Pathol.
  
  Volume: 188 Issue: 5 Pages: 1213-1224
- DOI
  10.1016/j.ajpath.2018.01.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0110, KAKENHI-PROJECT-16K08732, KAKENHI-PROJECT-17K10689, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-16H05171, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-16K10476, KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-18K06198, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-18K19575, KAKENHI-PUBLICLY-17H05500
[Journal Article] DEPDC5 deficiency contributes to resistance to leucine starvation via p62 accumulation in hepatocellular carcinoma2018
- Author(s)
  Mizuno Y, Shimada S, Akiyama Y, Watanabe S, Aida T, Ogawa K, Ono H, Mitsunori Y, Ban D, Kudo A, Arii S, Yamaoka S, Tanabe M, Tanaka S
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 106-106
- DOI
  10.1038/s41598-017-18323-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07085, KAKENHI-PROJECT-17K10689, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-15H04926, KAKENHI-PROJECT-18K19575
[Journal Article] Identification of selective inhibitors for diffuse-type gastric cancer cells by screening of annotated compounds in preclinical models.2018
- Author(s)
  Shimada S, Akiyama Y, Mogushi K, Ishigami-Yuasa M, Kagechika H, Nagasaki H, Fukamachi H, Yuasa Y, Tanaka S.
- Journal Title
  
  British Journal of Cancer
  
  Volume: - Issue: 7 Pages: 972-984
- DOI
  10.1038/s41416-018-0008-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-18K06572, KAKENHI-PROJECT-18K19575
[Journal Article] Meeting Report of the Fifth International Cancer Epigenetics Conference in Beijing, China, October 20162017
- Author(s)
  Gao D, Herman JG, Cui H, Jen J, Fuks F, Brock MV, Ushijima T, Croce C, Akiyama Y, Guo M.
- Journal Title
  
  Epigenomics
  
  Volume: 9 Issue: 7 Pages: 937-941
- DOI
  10.2217/epi-2017-0030
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08647
[Journal Article] ARID2 modulates DNA damage response in human hepatocellular carcinoma cells.2017
- Author(s)
  Oba A, Shimada S, Akiyama Y, Nishikawaji T, Mogushi K, Ito H, Matsumura S, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Asahara H, Kaida A, Miura M, Tanabe M, Tanaka S.
- Journal Title
  
  Journal of Hepatology
  
  Volume: in press Issue: 5 Pages: 942-951
- DOI
  10.1016/j.jhep.2016.12.026
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01484, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-15K19875, KAKENHI-PROJECT-26870175, KAKENHI-PROJECT-15K10035, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-16K10421, KAKENHI-PROJECT-17K10653, KAKENHI-PROJECT-17K10689, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-15H04926
[Journal Article] Acquired resistance with epigenetic alterations under long-term anti-angiogenic therapy for hepatocellular carcinoma.2017
- Author(s)
  Ohata Y, Akiyama Y, Shimada S, Mogushi K, Nakao K, Matsumura S, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Tanabe M, Tanaka S.
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: in press Issue: 6 Pages: 1155-1165
- DOI
  10.1158/1535-7163.mct-16-0728
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01484, KAKENHI-PROJECT-15H04926, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-15K19875, KAKENHI-PROJECT-26870175, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-16K10421, KAKENHI-PROJECT-17K10689, KAKENHI-PROJECT-16H02670
[Journal Article] Reduced expression of SET7/9, a histone mono-methyltransferase, is associated with gastric cancer progression.2016
- Author(s)
  Akiyama Y, Koda Y, Byeon S, Shimada S, Nishikawaji T, Sakamoto A, Chen Y, Kojima K, Kawano T, Eishi Y, Deng D, Kim WH, Zhu WG, Yuasa Y, Tanaka S.
- Journal Title
  
  Oncotarget
  
  Volume: 7(4) Issue: 4 Pages: 3966-3983
- DOI
  10.18632/oncotarget.6681
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01484, KAKENHI-PROJECT-25253081, KAKENHI-PROJECT-24590444, KAKENHI-PROJECT-16H02670
[Journal Article] CD73 as a therapeutic target for pancreatic neuroendocrine tumor stem cells.2016
- Author(s)
  Katsuta, E., Tanaka, S., Mogushi, K., Shimada, S., Akiyama, Y., Aihara, A., Matsumura, S., Mitsunori, Y., Ban, D., Ochiai, T., Kudo, A., Fukamachi, H., Tanaka, H., Nakayama, K., Arii, S., Tanabe, M.
- Journal Title
  
  Int. J. Oncol.
  
  Volume: 48 Issue: 2 Pages: 657-669
- DOI
  10.3892/ijo.2015.3299
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06832, KAKENHI-PROJECT-15K10035, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-15K19875, KAKENHI-PROJECT-25253081, KAKENHI-PROJECT-15H04926, KAKENHI-PROJECT-25462082, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-26870175, KAKENHI-PROJECT-26462025
[Journal Article] Dominant Expression of DCLK1 in Human Pancreatic Cancer Stem Cells Accelerates Tumor Invasion and Metastasis.2016
- Author(s)
  Ito H, Tanaka S, Akiyama Y, Shimada S, Adikrisna R, Matsumura S, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Arii S, Yamaoka S, Tanabe M.
- Journal Title
  
  Plos One
  
  Volume: - Issue: 1 Pages: e0146564-e0146564
- DOI
  10.1371/journal.pone.0146564
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19875, KAKENHI-PROJECT-25462082, KAKENHI-PROJECT-25640060, KAKENHI-PUBLICLY-15H01484, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-15K15491
[Journal Article] CD73 as a therapeutic target for pancreatic neuroendocrine tumor stem cells.2016
- Author(s)
  Katsuta E, Tanaka S, Mogushi K, Shimada S, Akiyama Y, Aihara A, Matsumura S, Mitsunori Y, Ban D, Ochiai T, Kudo A, Fukamachi H, Tanaka H, Nakayama K, Arii S, Tanabe M.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 48 Issue: 9 Pages: 657-69
- DOI
  10.1007/s00535-015-1159-8
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01484, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-26870175
[Journal Article] Proteasome activity is required for the initiation of precancerous pancreatic lesions.2016
- Author(s)
  Furuyama T, Tanaka S, Shimada S, Akiyama Y, Matsumura S, Mitsunori Y, Aihara A, Ban D, Ochiai T, Kudo A, Fukamachi H, Arii S, Kawaguchi Y, Tanabe M.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 27044-27044
- DOI
  10.1038/srep27044
- NAID
  120006775931
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01484, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-15K19875, KAKENHI-PROJECT-16K10421
[Journal Article] Expression of connective tissue growth factor in the livers of non-viral hepatocellular carcinoma patients with metabolic risk factors.2016
- Author(s)
  Akahoshi K, Tanaka S, Mogushi K, Shimada S, Matsumura S, Akiyama Y, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Arii S, Tanabe M.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: [Epub ahead of print]
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25253081
[Journal Article] Overexpression of histone methyltransferase SETDB2 acts an oncogene in gastric cancer.2016
- Author(s)
  Nishikawaji T, Akiyama Y, Shimada S, Kojima K, Kawano T, Eishi Y, Yuasa Y, Tanaka S.
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 41 Pages: 67251-67265
- DOI
  10.18632/oncotarget.11625
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-16K08647
[Journal Article] Dominant expression of DCLK1 in human pancreatic cancer stem cells accelerates tumor invasion and metastasis.2016
- Author(s)
  Ito H, Tanaka S, Akiyama Y, Shimada S, Adikrisna R, Matsumura S, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Arii S, Yamaoka S, Tanabe M.
- Journal Title
  
  PloS One
  
  Volume: 11
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25253081
[Journal Article] DNA methylation in the exon 1 region and complex regulation of Twist1 expression in gastric cancer.2015
- Author(s)
  Sakamoto A, Akiyama Y, Shimada S, Zhu W-G, Yuasa Y, Tanaka S.
- Journal Title
  
  PloS One
  
  Volume: 10(12) Issue: 12 Pages: e0145630-e0145630
- DOI
  10.1371/journal.pone.0145630
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01484, KAKENHI-PROJECT-25253081, KAKENHI-PROJECT-24590444
[Journal Article] Epigenetic silencing of microRNA-373 to epithelial-mesenchymal transition in non-small cell lung cancer through IRAK2 and LAMP1 axes.2014
- Author(s)
  Seol HS, Akiyama Y, Shimada S, Lee HJ, Kim TI, Chun SM, Singh SR, Jang SJ.
- Journal Title
  
  Cancer Letters
  
  Volume: 353 Issue: 2 Pages: 232-241
- DOI
  10.1016/j.canlet.2014.07.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590444
[Journal Article] Jumonji domain-containing protein 2B silencing induces DNA damage response via STAT3 pathway in colorectal cancer.2014
- Author(s)
  Chen L, Fu L, Kong X, Xu J, Wang Z, Ma X, Akiyama Y, Chen Y, Fang J.
- Journal Title
  
  British Journal of Cancer
  
  Volume: 110 Issue: 4 Pages: 1014-1026
- DOI
  10.1038/bjc.2013.808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590444
[Journal Article] 胃がん2013
- Author(s)
  秋山好光
- Journal Title
  
  遺伝子MOOK [エピジェネティクスと病気]
  
  Volume: 25 Pages: 64-69
- Data Source
  KAKENHI-PROJECT-24590444
[Journal Article] Circulating microRNAs as biomarkers for early detection of diffuse-type gastric cancer using a mouse model2013
- Author(s)
  Rotkrua P, Shimada S, Mogushi, K, Akiyama Y, Tanaka H, Yuasa Y
- Journal Title
  
  Brit. J. Cancer
  
  Volume: 108 Issue: 4 Pages: 932-940
- DOI
  10.1038/bjc.2013.30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300342, KAKENHI-PROJECT-24590444, KAKENHI-PROJECT-24650609
[Journal Article] Methylation of SUV39H1 by SET7/9 results in heterochromatin relaxation and genome instability.2013
- Author(s)
  Wang D, Zhou J, Liu X, Lu D, Shen C, Du Y, Wei FZ, Song B, Lu X, Yu Y, Wang L, Zhao Y, Wang H, Yang Y, Akiyama Y, Zhang H, Zhu WG.
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America
  
  Volume: 110 Issue: 14 Pages: 5516-5521
- DOI
  10.1073/pnas.1216596110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590444
[Journal Article] Multiple-to-multiple relationships between microRNAs and target genes in gastric cancel2013
- Author(s)
  Hashimoto Y, et al.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 5 Pages: e62589-e62589
- DOI
  10.1371/journal.pone.0062589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J04240, KAKENHI-PROJECT-23300342, KAKENHI-PROJECT-24590444, KAKENHI-PROJECT-24650609
[Journal Article] マイクロRNA発現異常とがん2012
- Author(s)
  秋山好光、湯浅保仁
- Journal Title
  
  Medical Science Digest
  
  Volume: 38 Pages: 12-15
- Data Source
  KAKENHI-PROJECT-21590396
[Journal Article] IGF2 hypomethylation of blood leukocyte DNA is associated with gastric cancer risk2012
- Author(s)
  Yuasa Y, et al.
- Journal Title
  
  Int.J.Cancer
  
  Volume: (in press) Issue: 11 Pages: 2596-2603
- DOI
  10.1002/ijc.27554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300342, KAKENHI-PROJECT-24590444, KAKENHI-PROJECT-24650609
[Journal Article] スキルス胃癌マウスモデル研究の展望.2012
- Author(s)
  島田周、秋山好光、湯浅保仁
- Journal Title
  
  日本臨床
  
  Volume: 70 Pages: 1660-1665
- Data Source
  KAKENHI-PROJECT-24590444
[Journal Article] MicroRNA-126 Inhibits SOX2 Expression and Contributes to Gastric Carcinogenesis.2011
- Author(s)
  Otsubo T, Akiyama Y, Hashimoto Y, Shimada S, Goto K, Yuasa Y
- Journal Title
  
  PLoS One 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390169
[Journal Article] MiR-9 down-regulates CDX2 expression in gastric cancer cells.2011
- Author(s)
  Rotkrua P, Akiyama Y, Hashimoto Y, Otsubo T, Yuasa Y
- Journal Title
  
  Int.J.Cancer in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390169
[Journal Article] MicroRNA-126 inhibits SOX2 expression and contributes to gastric carcinogenesis2011
- Author(s)
  Otsubo T, Akiyama Y, Hashimoto Y, Shimada S, Goto K, Yuasa Y
- Journal Title
  
  PLoS One
  
  Volume: 6
- Data Source
  KAKENHI-PROJECT-21590396
[Journal Article] microRNA発現プロファイルの胃癌診断への応用2011
- Author(s)
  秋山好光
- Journal Title
  
  胃がんPerspective
  
  Volume: 4 Pages: 12-19
- Data Source
  KAKENHI-PROJECT-21590396
[Journal Article] MiR-9 downregulates CDX2 expression in gastric cancer cells2011
- Author(s)
  Rotkrua P, Akiyama Y, Hashimoto Y, Otsubo T, Yuasa Y
- Journal Title
  
  International Journal of Cancer
  
  Volume: 129 Pages: 2611-2620
- Data Source
  KAKENHI-PROJECT-21590396
[Journal Article] miRNAを利用した癌診断2011
- Author(s)
  秋山好光
- Journal Title
  
  医学のあゆみ
  
  Volume: 238 Pages: 560-565
- Data Source
  KAKENHI-PROJECT-21590396
[Journal Article] miR-212 is down-regulated and suppresses the methyl-CpG-binding protein MeCP2 in human gastric cancers2010
- Author(s)
  Wada R, Akiyama Y, Hashimoto Y, Fukamachi H, Yuasa Y
- Journal Title
  
  International Journal of Cancer
  
  Volume: 127
- Data Source
  KAKENHI-PROJECT-21590396
[Journal Article] miR-212 is downregulated and suppresses methyl-CpG-binding protein MeCP2 in human gastric cancer.2010
- Author(s)
  Wada R, Akiyama Y, Hashimoto Y, Fukamachi H, Yuasa Y
- Journal Title
  
  Int.J.Cancer 127
  
  Pages: 1106-1114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390169
[Journal Article] Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis.2010
- Author(s)
  Hashimoto Y, Akiyama Y, Otsubo T, Shimada S, Yuasa Y
- Journal Title
  
  Carcinogenesis 31
  
  Pages: 777-784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis.2010
- Author(s)
  Hashimoto Y, Akiyama Y, Otsubo T, Shimada S, Yuasa Y
- Journal Title
  
  Carcinogenesis 31
  
  Pages: 777-784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390169
[Journal Article] Methylation of GATA-4 and GATA-5 and development of sporadic gastric carcinomas2010
- Author(s)
  Wen XZ, Akiyama Y, Pan KF, Liu ZJ, LuZM, Zhou J, Gu LK, Dong CX, Zhu BD, Ji JF, You WC, Deng DJ
- Journal Title
  
  World Journal of Gastro-enterology
  
  Volume: 16 Pages: 1201-1208
- Data Source
  KAKENHI-PROJECT-21590396
[Journal Article] Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis2010
- Author(s)
  Hashimoto Y, Akiyama Y, Otsubo T, Shimada S, Yuasa Y
- Journal Title
  
  Carcinogenesis
  
  Volume: 31 Pages: 777-784
- Data Source
  KAKENHI-PROJECT-21590396
[Journal Article] microRNAを利用した癌診断2009
- Author(s)
  秋山好光、橋本裕、湯浅保仁
- Journal Title
  
  遺伝子医学 15
  
  Pages: 152-156
- Data Source
  KAKENHI-PROJECT-21590396
[Journal Article] DNA methylation status is inversely correlated with green tea intake and physical activity in gastric cancer patients2009
- Author(s)
  Yuasa Y, Nagasaki H, Akiyama Y, 他6名
- Journal Title
  
  International Journal of Cancer 124
  
  Pages: 2677-2682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590340
[Journal Article] DNA methylation status is inversely correlated with green tea intake and physical activity in gastric cancer patients.2009
- Author(s)
  Yuasa Y, Nagasaki H, Akiyama Y, Hashimoto Y, Takizawa T, Kojima K, Kawano T, Sugihara K, Imai K, Nakachi K
- Journal Title
  
  Int.J.Cancer 124
  
  Pages: 2677-2682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390169
[Journal Article] GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer.2009
- Author(s)
  Hellebrekers DMEI, Lentjes, MHFM, van den Bosch SM, Wouters AD, Daenen K, Melotte V, Smits KM, Partouns-Hendriks IEJM, Akiyama Y, Yuasa Y, Sanduleanu S, Khalid-de Bakker C, Jonkers D, Weijenberg MP, Louwagie J, van Criekinge W, Carvalho B, Meijer GA, Baylin SB, Herman JG, de Bruine AP & van Engeland M
- Journal Title
  
  Clinical Cancer Res. 15
  
  Pages: 3990-3997
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer2009
- Author(s)
  Hellebrekers DMEI, Lentjes, MHFM, van den Bosch SM, Akiyama Y, 他18名
- Journal Title
  
  Clinical Cancer Research (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590340
[Journal Article] GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer.2009
- Author(s)
  Hellebrekers DMEI, Lentjes, MHFM, van den Bosch SM, Wouters AD, Daenen K, Melotte V, Smits KM, Partouns-Hendriks IEJM, Akiyama Y, Yuasa Y, Sanduleanu S, Khalid-de Bakker C, Jonkers D, Weijenberg MP, Louwagie J, van Criekinge W, Carvalho B, Meijer GA, Baylin SB, Herman JG, de Bruine AP, van Engeland M
- Journal Title
  
  Clinical Cancer Res. 15
  
  Pages: 3990-3997
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390169
[Journal Article] DNA methylation status is inversely correlated with green tea intake and physical activity in gastric cancer patients.2009
- Author(s)
  Yuasa Y, Nagasaki H, Akiyama Y, Hashimoto Y, Takizawa T, Kojima K, Kawano T, Sugihara K, Imai K, Nakachi K
- Journal Title
  
  Int. J. Cancer 124
  
  Pages: 2677-2682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] microRNA を利用した癌診断2009
- Author(s)
  秋山好光、橋本裕、湯浅保仁
- Journal Title
  
  遺伝子医学 15
  
  Pages: 152-156
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] microRNAを利用した癌診断2009
- Author(s)
  秋山好光、橋本裕、湯浅保仁
- Journal Title
  
  遺伝子医学
  
  Volume: MOOK15 Pages: 152-156
- Data Source
  KAKENHI-PROJECT-21590396
[Journal Article] GATA4 and GATA5are potential tumor suppressors andbiomarkers in colorectal cancer2009
- Author(s)
  Akiyama Y, Yuasa Y, Sanduleanu S, Khalid-de Bakker C, Jonkers D, Weijenberg MP, Louwagie J, van Criekinge W, CarvalhoB, Meijer GA, Baylin SB, Herman JG, deBru ne AP, van Engeland M
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 15 Pages: 3990-3997
- Data Source
  KAKENHI-PROJECT-21590396
[Journal Article] microRNAを利用した癌診断2009
- Author(s)
  秋山好光、橋本裕、湯浅保仁
- Journal Title
  
  遺伝子医学 15
  
  Pages: 152-156
- Data Source
  KAKENHI-PROJECT-20390169
[Journal Article] DNA methylation status is inversely correlated with green tea intake and physical activity in gastric cancer patients2009
- Author(s)
  Yuasa Y, Nagasaki H, Akiyama Y, Takizawa T, Kojima K, Kawano T, Sugihara K, Imai K, Nakachi K
- Journal Title
  
  International Journal of Cancer
  
  Volume: 124 Pages: 2677-2682
- Data Source
  KAKENHI-PROJECT-21590396
[Journal Article] IQGAP2 inactivation through aberrant promoter methylation and promotion of invasion in gastric cancer cells.2008
- Author(s)
  Jin S-H, Akiyama Y, et. al.
- Journal Title
  
  International Journal of Cancer 122
  
  Pages: 1040-1046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590340
[Journal Article] miRNA発現プロファイル解析による癌に診断への応用.2008
- Author(s)
  秋山好光, 湯浅保仁
- Journal Title
  
  実験医学 26
  
  Pages: 173-178
- Data Source
  KAKENHI-PROJECT-19590340
[Journal Article] IQGAP2 inactivation through aberrant promoter methylation and promotion of invasion in gastric cancer cells2008
- Author(s)
  Jin S-H, Akiyama Y, Fukamachi H, Yanagihara K, Akashi T & Yuasa Y
- Journal Title
  
  International Journal of Cancer 122
  
  Pages: 1040-1046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590340
[Journal Article] SOX2 is frequently down-regulated in gastric cancers and inhibits cell growth through cell cycle arrest and apoptosis.2008
- Author(s)
  Otsubo T, Akiyama Y, Yanagihara K, Yuasa Y
- Journal Title
  
  Brit. J. Cancer 98
  
  Pages: 824-831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] SOX2 is frequently down-regulated in gastric cancers and inhibits cell growth through cell cycle arrest and apoptosis2008
- Author(s)
  Otsubo T, Akiyama Y, Yanagihara K & Yuasa Y
- Journal Title
  
  British Journal of Cancer 98
  
  Pages: 824-831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590340
[Journal Article] IQGAP2 inactivation through aberrant promoter methylation and promotion of invasion in gastric cancer cells.2008
- Author(s)
  Jin S-H, Akiyama Y, Fukamachi H, Yanagihara K, Akashi T, Yuasa Y
- Journal Title
  
  Int. J. Cancer 122
  
  Pages: 1040-1046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] IQGAP2 inactivation through aberrant promoter methylation and promotion of invasion in gastric cancer cells.2008
- Author(s)
  Jin S-H, Akiyama Y, Fukamachi H, Yanagihara K, Akashi T, Yuasa Y
- Journal Title
  
  Int.J.Cancer 122
  
  Pages: 1040-1046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390169
[Journal Article] SOX2 is frequently downregulated in gastric cancers and inhibits cell growth through cell-cycle arrest and apoptosis.2008
- Author(s)
  Otsubo T, Akiyama Y, et. al.
- Journal Title
  
  Brotish Journal of Cancer 98
  
  Pages: 824-831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590340
[Journal Article] miRNA発現プロファイル解析による癌の診断への応用.2008
- Author(s)
  秋山好光, 湯浅保仁
- Journal Title
  
  実験医学 26
  
  Pages: 173-178
- Data Source
  KAKENHI-PROJECT-20390169
[Journal Article] Methylation of the calcium channel-related gene, CACNA2D3, is frequent and a poor prognostic factor in gastric cancer.2008
- Author(s)
  Wanajo A, Sasaki A, Nagasaki H, Shimada S, Otsubo T, Owaki S, Shimizu Y, Eishi Y, Kojima K, Nakajima Y, Kawano T, Yuasa Y, Akiyama Y
- Journal Title
  
  Gastroenterology 135
  
  Pages: 80-590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Methylation of the calcium channel-related gene, CACNA2D3, is frequent and a poor prognostic factor in gastric cancer2008
- Author(s)
  Wanajo A, Sasaki A, Nagasaki H, Shimada S, Otsubo T, Owaki S, Shimizu Y, Eishi Y, Kojima K, Nakajima Y, Kawano T, Yuasa Y & Akiyama Y
- Journal Title
  
  Gastroenterology 135
  
  Pages: 580-590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590340
[Journal Article] SOX2 is frequently down-regulated in gastric cancers and inhibits cell growth through cell cycle arrest and apoptosis.2008
- Author(s)
  Otsubo T, Akiyama Y, Yanagihara K, Yuasa Y
- Journal Title
  
  Brit.J.Cancer 98
  
  Pages: 824-831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390169
[Journal Article] miRNA発現プロファイル解析による癌に診断への応用2008
- Author(s)
  秋山好光, 湯浅保仁
- Journal Title
  
  実験医学 26
  
  Pages: 173-178
- Data Source
  KAKENHI-PROJECT-19590340
[Journal Article] Methylation of the calcium channel-related gene, CACNA2D3, is frequent and a poor prognostic factor in gastric cancer.2008
- Author(s)
  Wanajo A, Sasaki A, Nagasaki H, Shimada S, Otsubo T, Owaki S, Shimizu Y, Eishi Y, Kojima K, Nakajima Y, Kawano T, Yuasa Y, Akiyama Y
- Journal Title
  
  Gastroenterology 135
  
  Pages: 80-590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390169
[Journal Article] miRNA発現プロファイル解析による癌の診断への応用2008
- Author(s)
  秋山好光、湯浅保仁
- Journal Title
  
  実験医学 26
  
  Pages: 173-178
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Transciption factor SOX2 up-regulates stomach-specific pepsinogen A gene expression2007
- Author(s)
  Tani Y, Akiyama Y, Fukamachi H, Yanagihara K & Yuasa Y
- Journal Title
  
  Journal of Cancer Research and Clinical Oncology 133
  
  Pages: 263-269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590340
[Journal Article] Dual blockade of the Hedgehog and ERK1/2 pathways coordinately decreases proliferation and survival of cholangiocarcinoma cells2007
- Author(s)
  Jinawath A, Akiyama Y, Sripa B & Yuasa Y
- Journal Title
  
  Journal of Cancer Research and Clinical Oncology 133
  
  Pages: 271-278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590340
[Journal Article] Transcription factor SOX2 up-regulates stomach-specific pepsinogen A gene expression.2007
- Author(s)
  Tani Y, Akiyama Y, Fukamachi H, Yanagihara K, Yuasa Y
- Journal Title
  
  J. Cancer Res. Clin. Oncol. 133
  
  Pages: 263-269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Dual blockade of the Hedgehog and ERK1/2 pathways coordinately decreases proliferation and survival of cholangiocarcinoma cells.2007
- Author(s)
  Jinawath A, Akiyama Y, Sripa B, Yuasa Y
- Journal Title
  
  J. Cancer Res. Clin. Oncol. 133
  
  Pages: 271-278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Transcription factor SOX2 up-regulates stomach-specific pepsinogen Agene expression.2007
- Author(s)
  Tani Y, Akiyama Y, et. al.
- Journal Title
  
  Journal of Cancer Research and Clinical Oncology 133
  
  Pages: 263-269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590340
[Journal Article] Dual blockade of the Hedgehog and ERK1/2 pathways coordinately decreases proliferation and survival of cholangiocarcinoma cells.2007
- Author(s)
  Jinawath A, Akiyama Y, et. al.
- Journal Title
  
  Journal of Cancer Research and Clinical Oncology 133
  
  Pages: 271-278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590340
[Journal Article] Hath1 up-regulates gastric mucin genes in gastric cells.2006
- Author(s)
  Sekine A, Akiyama Y, Yanagihara K, Yuasa Y
- Journal Title
  
  Biochem. Biophys. Res. Commun. 344
  
  Pages: 1166-1171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Hypermethylation of the GATA gene family in esophageal cancer.2006
- Author(s)
  Guo M, House MG, Akiyama Y, Qi Y, Capagna DC, Harmon J, Baylin SB, Brock MV, Herman JG
- Journal Title
  
  Int. J. Cancer 119
  
  Pages: 2078-2083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Frequent epigenetic silencing of the bone morphogenetic protein 2 gene through methylation in gastric carcinomas.2006
- Author(s)
  Wen X-Z, Akiyama Y, Baylin SB, Yuasa Y
- Journal Title
  
  Oncogene 25
  
  Pages: 2666-2673
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Expression of phosphorylated ERK1/2 and homeodomain protein CDX2 in cholangiocarcinoma.2006
- Author(s)
  Jinawath A, Akiyama Y, Yuasa Y, Pairojkul C
- Journal Title
  
  J. Cancer Res. Clin. Oncol. 132
  
  Pages: 805-810
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Involvement of GATA-4/-5 transcription factors in ovarian carcinogenesis.2006
- Author(s)
  Wakana K, Akiyama Y, Aso T, Yuasa Y
- Journal Title
  
  Cancer Letters 241
  
  Pages: 281-288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Expression of homeodomain protein CDX2 in gallbladder carcinomas.2005
- Author(s)
  Wu XS, Akiyama Y, Igari T, Kawamura T, Hiranuma S, Shibata T, Tsuruta K, Koike M, Arii S, Yuasa Y
- Journal Title
  
  J. Cancer Res. Clin. Oncol. 131
  
  Pages: 271-278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Inactivation of the tissue inhibitor of metallortoteinases-2 gene by promoter hypermethylation in lymphoid malignancies.2005
- Author(s)
  Galm O, Suzuki H, Akiyama Y, Esteller M, Malcolm MV, Osieka R, Baylin SB, Herman JG
- Journal Title
  
  Oncogene 24
  
  Pages: 4799-4805
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Transcriptional regulation of the human DNA methyltransferase 3A and 3B genes by Sp3 and Sp1 zinc finger proteins.2005
- Author(s)
  Jinawath A, Miyake S, Yanagisawa Y, Akiyama Y, Yuasa Y
- Journal Title
  
  Biochemical J. 385
  
  Pages: 557-564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Relationship between CDX2 gene methylation and dietary factors in gastric cancer patients.2005
- Author(s)
  Yuasa Y, Nagasaki H, Akiyama Y, Sakai H, Nakajima T, Ohkura Y, Takizawa T, Koike M, Tani M, Iwai T, Sugihara K, Imai K, Nakachi K
- Journal Title
  
  Carcinogenesis 26
  
  Pages: 193-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] miR-212 is downregulated and suppresses methyl-CpG-binding protein MeCP2 in human gastric cancer.
- Author(s)
  Wada R, Akiyama Y, Hashimoto Y, Fukamachi H, Yuasa Y
- Journal Title
  
  Int. J. Cancer (in press.)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] 肝細胞癌におけるヒストンメチル化酵素SETDB1の癌促進因子としての影響2022
- Author(s)
  五十嵐陽介, 秋山好光, 丹治義明, 月原秀, 島田周, 新部彩乃, 池上徹, 田邊稔, 田中真二
- Organizer
  第33回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-20H03526
[Presentation] 膵癌におけるヒストンH3K4メチル化酵素SETD1A発現の臨床的及び生物学的意義2022
- Author(s)
  秋山好光, 島田周, 田邉稔, 田中真二.
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03526
[Presentation] CRISPR/Cas9システムを用いたエクソンスキッピングによるβ-cateninシグナルの内在性活性化が肝がん細胞の免疫回避に寄与する2022
- Author(s)
  島田周, 秋山好光, 田邉稔, 田中真二.
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03526
[Presentation] 肝臓外科からみた代謝関連肝癌の分子機序と治療戦略2021
- Author(s)
  田中真二、島田周、秋山好光、新部彩乃、波多野恵、下川雅弘、田邉稔、小川佳宏
- Organizer
  第7回肝臓と糖尿病・代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19H01055
[Presentation] 肝臓外科からみた代謝関連肝癌の分子機序と治療戦略2021
- Author(s)
  田中真二、島田周、秋山好光、新部彩乃、波多野恵、下川雅弘、田邉稔、小川佳宏
- Organizer
  第7回肝臓と糖尿病・代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21627
[Presentation] 肝細胞癌の分子生物学的免疫学的分類.2020
- Author(s)
  島田周、秋山好光、有井滋樹、田邉稔、田中真二
- Organizer
  第56 回日本肝癌研究会総会
- Data Source
  KAKENHI-PROJECT-20H03526
[Presentation] 胆管癌におけるARID1A 欠失はヒストンアセチル化を介して幹細胞遺伝子ALDH1A1 の発現亢進に働く.2020
- Author(s)
  秋山好光, 島田周, 田邉稔, 田中真二.
- Organizer
  第79 回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-20H03526
[Presentation] KDM6A 発現低下を特徴とする膵がん予後不良サブタイプにはHDAC 阻害剤が著効する.2020
- Author(s)
  島田周, 秋山好光, 田邉稔, 田中真二.
- Organizer
  第79 回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-20H03526
[Presentation] ARID1A欠失胆管癌における幹細胞遺伝子ALDH1A1の発現亢進とヒストン修飾変化の関与2020
- Author(s)
  秋山好光, 吉野潤, 島田周, 田邊稔, 田中真二.
- Organizer
  第22回日本肝がん分子標的治療研究会
- Data Source
  KAKENHI-PROJECT-20H03526
[Presentation] ゲノム医療・ゲノム編集時代におけるプレシジョン免疫複合療法WS-25-6（ワークショップ：基調講演）2019
- Author(s)
  田中真二、島田周、秋山好光、大庭篤志、渡辺秀一、奥野圭祐、水野裕貴、上田浩樹、吉野潤、菅原了子、小倉俊郎、小川康介、光法雄介、小野宏晃、伴大輔、工藤篤、大久保憲一、小嶋一幸、絹笠祐介、田邉稔
- Organizer
  第119回日本外科学会定期学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19575
[Presentation] 胃癌の増殖、進展におけるPRMT6高発現とヒストンH3アルギニンジメチル化の関与.2019
- Author(s)
  秋山好光, 奥野圭祐, 島田周, 田中真二.
- Organizer
  第13回日本エピジェネティクス研究会年会.
- Data Source
  KAKENHI-PROJECT-16K08647
[Presentation] プレシジョン・メディシンの外科学への応用　ゲノム医療・ゲノム編集時代におけるプレシジョン免疫複合療法.2019
- Author(s)
  田中真二, 島田周, 秋山好光, 大庭篤志, 渡辺秀一, 奥野圭祐, 水野裕貴, 上田浩樹, 吉野潤, 菅原了子, 小倉俊郎, 小川康介, 光法雄介, 小野宏晃, 伴大輔, 工藤篤, 大久保憲一, 小嶋一幸, 絹笠祐介, 田邉稔.
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K08647
[Presentation] 胃癌におけるヒストンアルギニンメチル化タンパク質PRMT6の高発現は予後と悪性度に関与する.2019
- Author(s)
  秋山好光, 島田周, 田中真二.
- Organizer
  第78回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08647
[Presentation] Overexpression of PRMT6 and histone H3 arginine 2 asymmetric dimethylation in gastric cancer2019
- Author(s)
  Akiyama Y, Okuno K, Shimada S, Tanaka S
- Organizer
  2019 Post-A3 Joint Symposium, Cancer Epigenetics and Cancer Stem Cell Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08647
[Presentation] 肝細胞癌の分子生物学的および免疫学的分類.2019
- Author(s)
  島田周, 秋山好光, 田中真二.
- Organizer
  第78回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08647
[Presentation] ゲノム医療・ゲノム編集時代におけるプレシジョン免疫複合療法WS-25-6（ワークショップ：基調講演）2019
- Author(s)
  田中真二、島田周、秋山好光、大庭篤志、渡辺秀一、奥野圭祐、水野裕貴、上田浩樹、吉野潤、菅原了子、小倉俊郎、小川康介、光法雄介、小野宏晃、伴大輔、工藤篤、大久保憲一、小嶋一幸、絹笠祐介、田邉稔
- Organizer
  第119回日本外科学会定期学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H01055
[Presentation] 膵内分泌腫瘍においてDAXX はヒストンH3.3/H3K9 トリメチル化を介して癌抑制因子として働く.2018
- Author(s)
  秋山好光, 島田周, 田邉稔, 田中真二.
- Organizer
  第77 回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08647
[Presentation] 肝細胞癌における高頻度変異および特異的免疫サブタイプの解明と免疫precision medicine への展開.2018
- Author(s)
  田中真二、大庭篤志、島田周、秋山好光、小川康介、小野宏晃、光法雄介、伴大輔、工藤篤、田邉稔.
- Organizer
  第73 回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-16K08647
[Presentation] 低分化型胃がんは、形成過程の異なる２つのクラスターに分類できる.2018
- Author(s)
  深町博史, 西川路武人, 島田周, 秋山好光, 湯浅保仁, 土屋輝一郎, 田中真二.
- Organizer
  第77 回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08647
[Presentation] メタボリック関連肝癌の腫瘍内星細胞におけるFABP4 発現亢進の意義.2018
- Author(s)
  島田周, 千代延記道, 秋山好光, 田中真二.
- Organizer
  第77 回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08647
[Presentation] Precision immunotherapy for hypermutator and immunogenic subtypes of hepatocellular carcinoma (Workshop)2018
- Author(s)
  Shinji Tanaka, Atsushi Oba, Shu Shimada, Yoshimitsu Akiyama, Kosuke Ogawa, Hiroaki Ono, Yusuke Mitsunori, Daisuke Ban, Atsushi Kudo, Shigeki Arii, Minoru Tanabe
- Organizer
  73rd General Meeting of the Japanese Society of Gastroenterological Surgery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02670
[Presentation] 肝細胞癌においてDEPDC5 不活化はｐ 62 発現上昇を介してロイシン欠乏に対する抵抗性の獲得に寄与する.2018
- Author(s)
  水野裕貴、島田　周、秋山好光、渡辺秀一、相田知海、小川康介、小野宏晃、光法雄介、伴　大輔、工藤　篤、山岡昇司、田中真二、田邉　稔.
- Organizer
  第77 回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08647
[Presentation] Precision immunotherapy for hypermutator and immunogenic subtypes of hepatocellular carcinoma (Workshop)2018
- Author(s)
  Shinji Tanaka, Atsushi Oba, Shu Shimada, Yoshimitsu Akiyama, Kosuke Ogawa, Hiroaki Ono, Yusuke Mitsunori, Daisuke Ban, Atsushi Kudo, Shigeki Arii, Minoru Tanabe
- Organizer
  73rd General Meeting of the Japanese Society of Gastroenterological Surgery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19575
[Presentation] ワークショップ「肝がん難治性サブタイプのゲノム編集解析とプレシジョン・メディシンによる治療戦略」2017
- Author(s)
  田中真二、大庭篤志、島田周、秋山好光、小川康介、小野宏晃、光法雄介、伴大輔、工藤篤、有井滋樹、田邉稔
- Organizer
  第56回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16H02670
[Presentation] Molecular mechanisms of SETDB2 histone methyltransferase overexpression in gastric cancer.2017
- Author(s)
  Akiyama Y, Nishikawaji T, Shimada S, Yuasa Y, Tanaka S
- Organizer
  第76回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-16K08647
[Presentation] 臨床で活用されているDNAメチル化診断技術とがんの早期発見・治療への期待2017
- Author(s)
  秋山好光
- Organizer
  がん早期診断の最新技術と実用化セミナー
- Data Source
  KAKENHI-PROJECT-16K08647
[Presentation] シンポジウム「肝胆膵がんの分子サブタイプと治療抵抗性解析によるprecision medicineの展開」2017
- Author(s)
  田中真二、島田周、秋山好光、松村聡、光法雄介、藍原有弘、落合高徳、伴大輔、工藤篤、有井滋樹、田邉稔
- Organizer
  第117回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16H02670
[Presentation] マウス胃がん細胞株を用いたTwist1発現における複合的なエピゲノム制御機構の解明2016
- Author(s)
  秋山好光、坂本鮎菜、島田周、湯浅保仁、田中真二.
- Organizer
  第10回日本エピジェネティクス研究会年会
- Place of Presentation
  千里ライフサイエンスセンター, 大阪
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-16K08647
[Presentation] 癌幹細胞のエピジェネティック変化と転移性および治療抵抗性獲得機序2016
- Author(s)
  田中真二、島田周、秋山好光
- Organizer
  第75回日本癌学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Data Source
  KAKENHI-PROJECT-16H02670
[Presentation] Expression changes of the histone methyltransferase genes, SETDB2, in gastric cancers2016
- Author(s)
  Akiyama Y, Nishikawaji T, Shimada S, Yuasa Y, Tanaka S.
- Organizer
  26th Seoul International Cancer Symposium
- Place of Presentation
  Seoul, 韓国
- Year and Date
  2016-06-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08647
[Presentation] Reduced expression of SET7/9, a histone mono-methyltransferase, is associated with gastric cancer progression2016
- Author(s)
  Akiyama Y, Nishikawaji T, Shimada S, Sakamoto A, Yuasa Y, Tanaka S.
- Organizer
  第75回日本癌学会総会
- Place of Presentation
  パシフィコ横浜, 横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K08647
[Presentation] シンポジウム：臨床検体のゲノム解析に基づいた遺伝子改変およびゲノム編集技術の臨床応用2016
- Author(s)
  田中真二、島田周、古山貴基、大庭篤志、茂櫛薫、秋山好光、水野裕貴、小川康介、深町博史、伊藤浩光、光法雄介、松村聡、藍原有弘、伴大輔、落合高徳、工藤篤、川口義弥、田邉稔
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  リーガロイヤルホテル大阪（大阪府、大阪市）
- Data Source
  KAKENHI-PROJECT-16H02670
[Presentation] Expression changes of the histone H3 lysine methyltransferase genes and their function in gastric cancer2016
- Author(s)
  Akiyama Y, Nishikawaji T, Shimada S, Deng D, Kim WH, Zhu WG, Yuasa Y, Tanaka S.
- Organizer
  5th International Cancer Epigenetics Meeting
- Place of Presentation
  Beijing, 中国
- Year and Date
  2016-10-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08647
[Presentation] 胃がんにおけるヒストンメチル化酵素SETDB2の標的遺伝子に対する発現制御機構2016
- Author(s)
  西川路武人, 秋山好光, 島田周, 湯浅保仁, 田中真二.
- Organizer
  第10回日本エピジェネティクス研究会年会
- Place of Presentation
  千里ライフサイエンスセンター, 大阪
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-16K08647
[Presentation] SETDB2 contributes to gastric cancer progression by deregulating the expression of tumor suppressor genes2016
- Author(s)
  Nishikawaji T, Akiyama Y, Shimada S, Yuasa Y, Tanaka S.
- Organizer
  第75回日本癌学会総会
- Place of Presentation
  パシフィコ横浜, 横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K08647
[Presentation] Reduced expression and its function of SET7/9, a histone methyltransferase gene, in gastric cancer2016
- Author(s)
  Akiyama Y, Nishikawaji T, Shimada S, Sakamoto A, Deng D, Kim WH, Zhu WG, Yuasa Y, Tanaka S.
- Organizer
  The 35th Sapporo International Cancer Symposium
- Place of Presentation
  ロイトン札幌, 札幌
- Year and Date
  2016-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08647
[Presentation] Identification of selective inhibitors of diffuse-type gastric cancer cells by screening of annotated compounds.2015
- Author(s)
  Shimada S, Akiyama Y, Fukamachi H, Yuasa Y, Tanaka S.
- Organizer
  第74回日本癌学会総会
- Place of Presentation
  名古屋国際会議場 (愛知県名古屋市)
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] Oncogenic roles of SETDB2, a histone methyltransferase, in human gastric carcinogenesis.2015
- Author(s)
  Nishikawaji T, Akiyama Y, Shimada S, Yuasa Y, Tanaka S.
- Organizer
  第74回日本癌学会総会
- Place of Presentation
  名古屋国際会議場 (愛知県名古屋市)
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] 胃がん細胞におけるヒストン修飾関連遺伝子SET7/9の発現調節機構の解析.2015
- Author(s)
  秋山好光、西川路武人、島田周、坂本鮎菜、湯浅保仁、田中真二.
- Organizer
  第9回日本エピジェネティクス研究会年会
- Place of Presentation
  東京一ツ橋学術総合センター (東京都千代田区)
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] Epigenetic regulation of Twist1 in diffuse-type gastric cancer cell lines of an E-cadherin/p53-deficient mouse model.2015
- Author(s)
  Sakamoto A, Shimada S, Akiyama Y, Yuasa Y, Tanaka S.
- Organizer
  第74回日本癌学会総会
- Place of Presentation
  名古屋国際会議場 (愛知県名古屋市)
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] ヒストンメチル化酵素SETDB2の胃がんにおける発現亢進とその標的遺伝子の同定.2015
- Author(s)
  西川路武人、秋山好光、島田周、湯浅保仁、田中真二.
- Organizer
  第9回日本エピジェネティクス研究会年会
- Place of Presentation
  東京一ツ橋学術総合センター (東京都千代田区)
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] Features of poorly-differentiated gastric tumor-initiating cells from patient-derived tumor xenograft tissues.2015
- Author(s)
  Fukamachi H, Shimada S, Akiyama Y, Yuasa Y, Tsuchiya K, Tanaka S.
- Organizer
  第74回日本癌学会総会
- Place of Presentation
  名古屋国際会議場 (愛知県名古屋市)
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] Transcriptional regulatory mechanism of SET7/9 in gastric cancer.2015
- Author(s)
  Akiyama Y, Koda Y, Nishikawaji N, Shimada S, Sakamoto A, Yuasa Y, Tanaka S.
- Organizer
  第74回日本癌学会総会
- Place of Presentation
  名古屋国際会議場 (愛知県名古屋市)
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] 生活習慣とエピジェネティクス2014
- Author(s)
  秋山好光
- Organizer
  エピジェネティック療法研究会第6回講演会
- Place of Presentation
  品川、東京
- Invited
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] 食事がエピジェネティクスに与える影響、及びがんとの関係2013
- Author(s)
  秋山好光
- Organizer
  第13回抗加齢医学の実際2013
- Place of Presentation
  品川、東京
- Invited
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] ヒストン修飾関連遺伝子SET7/9の胃がんにおける発現低下と機能解析.2013
- Author(s)
  秋山好光、甲田裕樹、西川路武人、島田周、Woo Ho Kim、Wei-Guo Zhu、湯浅保仁
- Organizer
  第7回日本エピジェネティクス研究会年会
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] 胃がんにおけるヒストンメチル化酵素SETDB2の異常と機能の解析.2013
- Author(s)
  西川路武人、秋山好光、島田周、湯浅保仁.
- Organizer
  第7回日本エピジェネティクス研究会年会
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] Frequent loss of SET7/9 protein and its clinicopathological significance in gastric carcinoma.2013
- Author(s)
  Akiyama Y, Koda Y, Nishikawaji T, Shimada S, Yuasa Y.
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] Loss of SET7, a histone H3K4 methyltransferase, and its function in gastric cancer.2012
- Author(s)
  Akiyama Y, Koda Y, Nishikawaji T, Shimada S, Yuasa Y.
- Organizer
  第71回日本癌学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] 胃がんにおけるヒストン修飾関連遺伝子SET7の異常とその機能解析.2012
- Author(s)
  秋山好光、甲田裕樹、橋本裕、湯浅保仁.
- Organizer
  第６回に本エピジェネティクス研究会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] Identification of circulating miRNA as biomarkers for early detection of diffuse-type gastric cancer using a mouse model.2012
- Author(s)
  Shimada S, Rotkrua P, Akiyama Y, Yuasa Y.
- Organizer
  第71回日本癌学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] Loss of SET7, a histone H3K4 methyltransferase, in gastric cancer.2012
- Author(s)
  Akiyama Y, Koda Y, Nishikawaji N, Shimada S, Zhu WG, Yuasa Y.
- Organizer
  The Third International Cancer Epigenetics Meeting
- Place of Presentation
  北京、中国
- Invited
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] 転写因子GATA4/5によるmiRNAの発現解析2011
- Author(s)
  秋山好光、鈴木裕介、橋本裕、甲田祐樹、芝紀代子、湯浅保仁
- Organizer
  第5回日本エピジェネティクス研究会年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] Target gene analysis of GATA4 and GATA5 transcription factors in gastric cancer cells2011
- Author(s)
  Akiyama Y, 他
- Organizer
  The 10^<th> Japan-Korea Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  東京
- Year and Date
  2011-02-15
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] Up-regulation of miRNAs by treatment with the chromatin-modifying drugs and identification of common target genes in gastric cancer cells2011
- Author(s)
  Hashimoto Y, Akiyama Y, Otsubo T, YuasaY
- Organizer
  NRF A3 Foresight Program IGCC2011
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] Mir-9 downregulates CDX2 expression in gastric cancer cells2011
- Author(s)
  Pichayanoot R, Akiyama Y, Hashimoto Y, Otsubo T, Yuasa Y
- Organizer
  NRF A3 Foresight Program IGCC2011
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] 胃がん細胞において脱メチル化剤処理により発現増加する複数のmiRNAとその共通の標的遺伝子の検出2011
- Author(s)
  橋本裕、秋山好光、湯浅保仁
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] 胃がん細胞における転写因子GATA4およびGATA5のmiRNA発現調節への関与2011
- Author(s)
  秋山好光、鈴木裕介、橋本裕、甲田祐樹、芝紀代子、湯浅保仁
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] Target gene analysis of GATA4 and GATA5 transcription factors in gastric cancer cells2011
- Author(s)
  Akiyama Y, Nagasaki H, Yuasa Y
- Organizer
  The 10th Japan-Korea Joint Symposium on Cancer and Ageing
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] Epigenetic alterations of GATA4 and GATA5 transcription factors in gastric cancers2011
- Author(s)
  Akiyama Y, Nagasaki H, Yuasa Y
- Organizer
  NRF A3 Foresight Program IGCC2011
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] Epigenetic alterations of GATA4 and GATA5 transcription factors in gastric cancers2011
- Author(s)
  Akiyama Y, 他
- Organizer
  IGCC 2011-9^<th> International Gastric Cancer Congress
- Place of Presentation
  Seoul, Korea
- Year and Date
  2011-04-21
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] 胃癌におけるhistoneH3K4 methyltransferase SET7の変化と機能の解析2011
- Author(s)
  甲田祐樹、秋山好光、橋本裕、大坪武史、芝紀代子、湯浅保仁
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] GATA4 and GATA5 transcription factors regulate miRNAs in gastric cancer cells2011
- Author(s)
  Akiyama Y, 他
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] Target gene analysis of GATA4 and GATA5 transcription factors in gastric cancer cells2011
- Author(s)
  Akiyama Y, 他
- Organizer
  The 10^<th> japan-Korea Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  東京
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] The target gene analyses of GATA4/5 transcription factors in gastric cancer.2010
- Author(s)
  秋山好光, 他
- Organizer
  第4回日本エピジェネティクス研究会年会
- Place of Presentation
  鳥取
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] 胃がん細胞における転写因子GATA4とGATA.5転写因子の標的遺伝子の解析2010
- Author(s)
  秋山好光, 他
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] Targetgene analysis of GATA4/5 transcriptionfactors in gastric cancers2010
- Author(s)
  Akiyama Y, Nagasaki H, Yuasa Y
- Organizer
  The 5th Asian Epigenomics Meeting & A3 Symposium 2010
- Place of Presentation
  Jeju, Korea
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] Target gene analysis of GATA4 and GATA5 transcription factors in gastric cancer cells.2010
- Author(s)
  Akiyama Y, 他
- Organizer
  NSFC A3 Foresight Program 2010 Seminar
- Place of Presentation
  Beijing, 中国
- Year and Date
  2010-10-18
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] Epigenetic epidemiology of gastric cancer.2010
- Author(s)
  Yuasa Y, Hashimoto Y, Nagasaki H, Akiyama Y, Kojima K, Oze I, Matsuo K, Imai K, Nakachi K
- Organizer
  International Workshop, at Radiation Effect Research Foundation.
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] The target gene analyses of GATA4/5 transcription factors in gastric cancer.2010
- Author(s)
  秋山好光, 他
- Organizer
  第4回日本エピジェネティクス研究会年会
- Place of Presentation
  鳥取
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] Epigenetic epidemiology of gastric cancer.2010
- Author(s)
  Yuasa Y, Hashimoto Y, Nagasaki H, Akiyama Y, Kojima K, Oze I, Matsuo K, Imai K, Nakachi K
- Organizer
  The 5th Asian Epigenomics Meeting & A3 Symposium 2010
- Place of Presentation
  Jeju, Korea.
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] Epigenetic epidemiology of gastric cancer.2010
- Author(s)
  Yuasa Y, Nagasaki H, Akiyama Y, Kojima K, Oze I, Matsuo K, Imai K, Nakachi K
- Organizer
  JSPS A3 Foresight Program 2010 Seminar-Epigenetic Signatures in Gastric Carcinogenesis
- Place of Presentation
  葉山
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] Hypermethylation of GATA4 and GATA5 transcription factor genes and loss of their functions in gastric cancers.2010
- Author(s)
  Akiyama Y, 他
- Organizer
  The Second International Cancer Epigenetics Symposium
- Place of Presentation
  Beijing, 中国
- Year and Date
  2010-10-17
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] Hypermethylation of GATA4 and GATA5 transcription factor genes and loss of their functions in gastric cancers.2010
- Author(s)
  Akiyama Y, 他
- Organizer
  The Second International Cancer Epigenetics Symposium
- Place of Presentation
  Beijin, 中国
- Year and Date
  2010-10-17
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] MicroRNA-126 inhibits SOX2 expression in gastric cancer cells2010
- Author(s)
  Otsubo T, Akiyama Y, Hashimoto Y, Yuasa Y
- Organizer
  101^<st> AACR Annual Meeting
- Place of Presentation
  Washington DC
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] Target gene analysis of GATA4 and GATA5 transcription factors in gastric cancer cells.2010
- Author(s)
  Akiyama Y, 他
- Organizer
  NSFC A3 Foresight Program 2010 Seminar
- Place of Presentation
  Beijin, 中国
- Year and Date
  2010-10-18
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] Target gene analysis of GATA4/5 transcription factors in gastric cancers.2010
- Author(s)
  Akiyama Y, 他
- Organizer
  The 5th Asian Epigenomics Meeting & A3Symposium 2010
- Place of Presentation
  Jeju Island, 韓国
- Year and Date
  2010-06-21
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] Hypermethylation of GATA4 and GATA5 transcription factor genes and loss of their functions in gastric cancers2010
- Author(s)
  Akiyama Y, Nagasaki H, Yuasa Y
- Organizer
  The Second International Cancer Epigenetics Symposium
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] Methylation of GATA4 and GATAS transcription factor genes in gastric cancers.2010
- Author(s)
  Akiyama Y, 他
- Organizer
  101^<st> AACR Annual Meeting
- Place of Presentation
  Washington DC, 米国
- Year and Date
  2010-04-18
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] 胃がんにおけるmiRNAクラスターの発現とメチル化の解析2010
- Author(s)
  橋本裕、秋山好光、大坪武史、湯浅保仁
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] Methylation of GATA4 and GATA5 transcription factor genes in gastric cancers.2010
- Author(s)
  Akiyama Y, 他
- Organizer
  101^<St> AACR Annual Meeting
- Place of Presentation
  Washington DC, 米国
- Year and Date
  2010-04-18
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] マイクロRNA-126はSOX2発現を抑制し胃がん発症に関わる2010
- Author(s)
  大坪武史、秋山好光、橋本裕、湯浅保仁
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] Target gene analysis of GATA4/5 transcription factors in gastric cancers.2010
- Author(s)
  Akiyama Y, 他
- Organizer
  The 5th Asian Epigenomics Meeting & A3Symposium2010
- Place of Presentation
  Jeju Island韓国
- Year and Date
  2010-06-21
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] The target gene analyses of GATA4/5 transcription factors in gastric cancer2010
- Author(s)
  秋山好光、長崎弘美、湯浅保仁
- Organizer
  第4回日本エピジェネティクス研究会年会
- Place of Presentation
  鳥取
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] 胃がん細胞におけ+る転写因子GATA4とGATA5転写因子の標的遺伝子の解析2010
- Author(s)
  秋山好光, 他
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] Relationship between the methylation state of blood leukocyte DNA and carcinogenesis.2010
- Author(s)
  湯浅保仁、長崎弘美、秋山好光、尾瀬功、松尾恵太郎
- Organizer
  第4回日本エピジェネティクス研究会年会
- Place of Presentation
  鳥取
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] Epigenetic inactivation of the miR-9 genes in gastric carcinogenesis through CDX2 deregulation2010
- Author(s)
  Pichayanoot R, Akiyama Y, Hashimoto Y, Yuasa Y
- Organizer
  The 5th Asian Epigenomics Meeting & A3 Symposium 2010
- Place of Presentation
  Jeju, Korea
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] Methylation of GATA4 and GATA5 transcription factor genes in gastric cancers2010
- Author(s)
  Akiyama Y, Nagasaki H, Kawamoto A, Herman JG, Baylin SB, Yuasa Y
- Organizer
  101^<st> AACR Annual Meeting
- Place of Presentation
  Washington DC
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] 胃がんにおける転写関連遺伝子GATA4/5のメチル化異常と機能解析2009
- Author(s)
  秋山好光、長崎弘美、湯浅保仁
- Organizer
  第3回日本エピジェネティクス研究会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] Tnvolvement of epigenetically silenced microRNA-181c in gastric carcinogenesis2009
- Author(s)
  Akiyama Y, 他
- Organizer
  9^<th> Korea-Japan Symposium on Cancer and Ageing Research
- Place of Presentation
  Damvang, 韓国
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] 胃がんにおける転写関連遺伝子GATA4/5のメチル化異常と機能解析2009
- Author(s)
  秋山好光, 他
- Organizer
  第3回日本エピジェネティクス研究会年会
- Place of Presentation
  東京
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] 胃がん発症におけるGATA4とGATA5転写因子の役割2009
- Author(s)
  秋山好光, 他
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] CpGアイランドメチル化によるmiRNA-181cの胃がんにおけるエピジェネティックな発現低下2009
- Author(s)
  橋本裕、秋山好光、大坪武史、島田周、湯浅保仁
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] 胃がんにおける転写関連遺伝子GATA4/5のメチル化異常と機能解析2009
- Author(s)
  秋山好光, 他
- Organizer
  第3回日本エピジェネティクス研究会年会
- Place of Presentation
  東京
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] 胃がん発症におけるGATA4とGATA5転写因子の役割2009
- Author(s)
  秋山好光、長崎弘美、湯浅保仁
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590396
[Presentation] 胃がんのエピジェネティック疫学2009
- Author(s)
  湯浅保仁、長崎弘美、秋山好光、小嶋一幸、松尾恵太郎、今井一枝、中地敬
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] Involvement of epigenetically silenced microRNA-181c in gastriccarcinogenesis.2009
- Author(s)
  Akiyama Y, 他.
- Organizer
  9^<th> Korea-Japan Symposium on Cancer and Ageing Research.
- Place of Presentation
  Damyang, 韓国
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] 胃がんのエピジェネティック疫学2009
- Author(s)
  湯浅保仁、長崎弘美、秋山好光、小嶋一幸、松尾恵太郎、今井一枝、中地敬
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] 胃がん発症におけるGATA4とGATA5転写因子の役割2009
- Author(s)
  秋山好光, 他
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] 胃がん発症における電位依存性カルシウムチャンネル関連遺伝子のメチル化2008
- Author(s)
  秋山好光、他
- Organizer
  第2回日本エピジェネティクス研究会年会
- Place of Presentation
  三島
- Year and Date
  2008-05-10
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] 胃がん細胞における転写因子GATA5の標的遺伝子の解析2008
- Author(s)
  秋山好光, 他
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] Promoter hyper methylation of the calcium channel-related gene, CACNA2D3, is frequent and an independently poor prognostic factor in gastric carcinomas2008
- Author(s)
  Akiyama Y, 他
- Organizer
  AACR 99th Annual Meeting 2008
- Place of Presentation
  San Diego, 米国
- Year and Date
  2008-04-15
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] DNA methylation status is inversely correlated with green tea intake and physical activity in gastric cancer patients.2008
- Author(s)
  湯浅保仁, 長崎弘美, 秋山好光, 今井一枝, 中地敬
- Organizer
  Northeastern Asian Symposium on "Cancer Epigenetics"
- Place of Presentation
  Jeju Island, Korea
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] 胃がん発症における電位依存性カルシウムチャンネル関連遺伝子のメチル化.2008
- Author(s)
  秋山好光, 他.
- Organizer
  第2回日本エピジェネティクス研究会年会
- Place of Presentation
  三島
- Year and Date
  2008-05-10
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] Promoter hypermethylation of the calcium channel-related gene, CACNA2D3, is frequent and an independently poor prognostic factor in gastric carcinomas.2008
- Author(s)
  Akiyama Y, 他.
- Organizer
  AACR 99th Annual Meeting 2008
- Place of Presentation
  San Diego, 米国
- Year and Date
  2008-04-15
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] 胃がん細胞におけるIQGAP2遺伝子のメチル化によるサイレンシングと浸潤能の亢進2008
- Author(s)
  湯浅保仁、金順花、深町博史、秋山好光
- Organizer
  第9回日本がん分子疫学研究会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] DNA methylation status is inversely correlated with green tea intake and physical activity in gastric cancer patients.2008
- Author(s)
  Yuasa Y, Nagasaki H, Akiyama Y, Imai K, Nakachi K.
- Organizer
  Northeastern Asian Symposium on "Cancer Epigenetics"
- Place of Presentation
  Jeju Island, Korea
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] 胃がんにおける転写関連遺伝子GATA4/5のメチル化異常と機能解析.2008
- Author(s)
  秋山好光, 他.
- Organizer
  BMB2008 第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] 胃がん細胞における転写因子GAIA5の標的遺伝子の解析2008
- Author(s)
  秋山好光, 他
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] 胃がん細胞における転写因子GATA5の標的遺伝子の解析.2008
- Author(s)
  秋山好光, 他.
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] 胃がん発症における電位依存性カルシウムチャンネル関連遺伝子のメチル化2008
- Author(s)
  秋山好光, 他
- Organizer
  第2回日本エピジェネティクス研究会年会
- Place of Presentation
  三島
- Year and Date
  2008-05-10
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] Promoter hypermethylation of the calcium channel-related gene, CACNA2D3, is frequent and an independently poor prognostic factor in gastric carcinomas.2008
- Author(s)
  Akiyama Y, 他.
- Organizer
  AACR 99th Annual Meeting
- Place of Presentation
  San Diego, 米国
- Year and Date
  2008-04-15
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] 胃がん細胞における転写因子GATA5の標的遺伝子の解析2008
- Author(s)
  秋山好光, 他.
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] 胃のがん化におけるDNAメチル化とマイクロRNAの関与2008
- Author(s)
  湯浅保仁、長崎弘美、橋本裕、秋山好光、今井一枝、中地敬
- Organizer
  第2回日本エピジェネティクス研究会年会
- Place of Presentation
  三島
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] 胃がん発症における電位依存性カルシウムチャンネル関連遺伝子のメチル化2008
- Author(s)
  秋山好光, 他.
- Organizer
  第2回日本エピジェネティクス研究会年会
- Place of Presentation
  三島
- Year and Date
  2008-05-10
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] 胃がんにおける転写関連遺伝子GATA4/5のメチル化異常と機能解析2008
- Author(s)
  秋山好光, 他
- Organizer
  BMB2008第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] 胃がん細胞におけるIQGAP2遺伝子のメチル化によるサイレンシングと浸潤能の亢進2008
- Author(s)
  湯浅保仁、金順花、深町博史、秋山好光
- Organizer
  第9回日本がん分子疫学研究会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20390169
[Presentation] 胃のがん化におけるDNAメチル化とマイクロRNAの関与.2008
- Author(s)
  湯浅保仁、長崎弘美、橋本裕、秋山好光、今井一枝、中地敬
- Organizer
  第2回日本エピジェネティクス研究会年会
- Place of Presentation
  三島
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] GATA4 and GATA5 transcription factor genes were frequently silenced by methylation in gastric cancer2007
- Author(s)
  Akiyama Y, Nagasaki H, Kawamoto A, Yuasa Y
- Organizer
  The 8th Korea-Japan Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] GATA4 and GATA5 transcription factor genes were frequently silenced by methylation in gastric cancer2007
- Author(s)
  Akiyama Y, Nagasaki H, Kawamoto A, Yuasa Y
- Organizer
  The 8th Korea-Japan Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390178
[Presentation] 転写因子GATA-5の遺伝子プロモーター領域の解析2007
- Author(s)
  秋山好光, 他
- Organizer
  第1回日本エピジェネティクス研究会年会
- Place of Presentation
  大阪
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] Frequent methylation of GATA4 and GATA5 transcription factor genes in gastric cancer2007
- Author(s)
  Akiyama Y, et. al.
- Organizer
  66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390178
[Presentation] Frequent methylation of GATA4 and GATA5 transcription. factor genes in gastric cancer.2007
- Author(s)
  秋山好光、他
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] 胃がんにおけるメチル化異常とエピジェネティクス疫学.2007
- Author(s)
  湯浅保仁, 長崎弘美, 秋山好光, 今井一枝, 中地敬
- Organizer
  第14回日本がん予防学会・第8回日本がん分子疫学研究会・第30回日本がん疫学研究会合同大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] IQGAP2 inactivation through aberrant promoter methylation and promotion of invasion in gastric cancer cells.2007
- Author(s)
  Jin S-H, Akiyama Y, 他
- Organizer
  The 8th Korea-Japan Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] Expression analysis of microRNA in gastric cancer2007
- Author(s)
  和田りえ、秋山好光、深町博史、湯浅保仁
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] Frequent methylation of GATA4 and GATA5 transcription. factor genes in gastric cancer2007
- Author(s)
  秋山好光、長崎弘美、河本絢子、湯浅保仁
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] Sox2, epigenetically silenced in gastric cancers, inhibits growth through cell cycle arrest and apoptosis2007
- Author(s)
  Otsubo T, Akiyama Y, Yanagihara K, Yuasa Y
- Organizer
  The 8th Korea-Japan Joint Symposium on Cancer and Ageing Researc
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] Sox2 inhibits growth of gastric epithelial cell lines through cell cycle arrest and apoptosis2007
- Author(s)
  Otsubo T, Akiyama Y, Yuasa Y.
- Organizer
  AACR (American Association for Cancer research) 97th Annual Meeting
- Place of Presentation
  Los Angeles,米国
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] 転写因子GATA-5の遺伝子プロモーター領域の解析2007
- Author(s)
  秋山好光、大脇秀一、湯浅保仁
- Organizer
  第1回日本エピジェネティクス研究会年会
- Place of Presentation
  大阪
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] 転写因子GATA-5の遺伝子プロモーター領域の解析.2007
- Author(s)
  秋山好光、他
- Organizer
  第1回日本エピジェネティクス研究会年会
- Place of Presentation
  大阪
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] GATA4 and GATA5 transcription factor genes were frequently silenced by methylation in gastric cancer2007
- Author(s)
  Akiyama Y, 他
- Organizer
  The 8^<th> Korea-Japan Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] Sox2, epigenetically silenced in gastric cancers, inhibits growth through cell cycle arrest and apoptosis2007
- Author(s)
  Otsubo T, Akiyama Y, Yanagihara K, Yuasa Y
- Organizer
  The 8th Korea-Japan Joint Svmnosium on Cancer and Ageing Research
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-18390178
[Presentation] 転写因子GATA-5の遺伝子プロモーター領域の解析2007
- Author(s)
  秋山好光、大脇秀一、湯浅保仁
- Organizer
  第1回日本エピジェネティクス研究会年会
- Place of Presentation
  大阪
- Year and Date
  2007-06-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390178
[Presentation] Loss of transcription factor GATA-4/-5 by hypermethylation correlated with progression of gastric carcinomas.2007
- Author(s)
  Wen X-Y、Akiyama Y, 他
- Organizer
  AACR 97th Annual Meeting
- Place of Presentation
  Los Angeles,米国
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] Hypermethylation of GATA4 and GATA5 transcription factor genes in gastric cancer2007
- Author(s)
  Akiyama Y, 他
- Organizer
  The 12^<th> Korea-Japan Cancer Research Workshop
- Place of Presentation
  札幌
- Year and Date
  2007-12-02
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] Hypermethylation of GATA4 and GATA5 transcription factor genes in gastric cancer.2007
- Author(s)
  Akiyama Y, Yuasa Y.
- Organizer
  The 12th Korea-Japan Cancer Research Workshop
- Place of Presentation
  札幌
- Year and Date
  2007-12-22
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] Frequent methylation of GATA4 and GATA5 transcription factor genes in gastric cancer2007
- Author(s)
  秋山好光, 他
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] Hypermethylation of GATA4 and GATA5 transcription factor genes in gastric cancer.2007
- Author(s)
  Akiyama Y, Yuasa Y
- Organizer
  The 12th Korea-Japan Cancer Research Workshop
- Place of Presentation
  札幌
- Year and Date
  2007-12-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390178
[Presentation] 胃がんにおける転写関連遺伝子GATA4/5のメチル化の解析.2007
- Author(s)
  秋山好光、他
- Organizer
  第14回日本がん予防学会・第8回日本がん分子疫学研究会・第30回日本がん疫学研究会合同大会
- Place of Presentation
  東京
- Year and Date
  2007-07-13
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] 胃がんにおける転写関連遺伝子GATA4/5のメチル化の解析2007
- Author(s)
  秋山好光, 他
- Organizer
  第14回日本がん予防学会・第8回日本がん分子疫学研究会・第30回日本がん疫学研究会合同大会
- Place of Presentation
  東京
- Year and Date
  2007-07-13
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] GATA4 and transcription factor genes were frequently silenced by methylation in gastric cancer2007
- Author(s)
  Akiyama Y, Nagasaki H, Kawamoto A, Yuasa Y
- Organizer
  The 8th Korea-Japan Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-18390178
[Presentation] GATA4 and GATA5 transcription factor genes were frequently silenced by methylation in gastric cancer2007
- Author(s)
  Akiyama Y, et. al.
- Organizer
  The 8th Korea-Japan Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  Gifu, Japan
- Year and Date
  2007-08-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390178
[Presentation] 転写固子GATA-5の遺伝子プロモーター領域の解析.2007
- Author(s)
  秋山好光、大脇秀一、湯浅保仁
- Organizer
  第1回日本エピジェネティクス研究会年会
- Place of Presentation
  大阪
- Year and Date
  2007-06-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390178
[Presentation] Relationship between DNA methylation and epidemiological factors in gastric cancer patients.2007
- Author(s)
  湯浅保仁, 長崎弘美, 秋山好光, 今井一枝, 中地敬
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] Epigenetic silencing of SOX2 by DNA methylation in gastric cancers.2007
- Author(s)
  大坪武史、秋山好光、湯浅保仁.
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] 胃がんにおけるメチル化異常と疫学的因子との関連..2007
- Author(s)
  湯浅保仁, 長崎弘美, 秋山好光, 今井一枝, 中地敬
- Organizer
  第1回日本エピジェネティクス研究会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] Sox2 inhibits growth of gastric epithelial cell lines through cell cycle arrest and apoptosis.2007
- Author(s)
  Otsubo T, Akiyama Y. Yuasa Y.
- Organizer
  AACR (American Association for Cancer research)97th Annual Meeting
- Place of Presentation
  Los Angeles,米国
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] Sox2, epigentically silenced in gastric cancers, inhibits growth through cell cycle arrest and apoptosis2007
- Author(s)
  Otsubo T, Akiyama Y, Yanagihara K, Yuasa Y
- Organizer
  The 8th Korea-Japan Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390178
[Presentation] Relationship between DNA methylation and epidemiological factors in gastric cancer patients.2007
- Author(s)
  湯浅保仁、長崎弘美、秋山好光、他
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] Sox2 inhibits growth of gastric epithelial cell lines through cell cycle arrest and apoptosis2007
- Author(s)
  Otsubo T, Akiyama Y, Yuasa Y.
- Organizer
  AACR (American Association for Cancer research) 97th Annual Meeting
- Place of Presentation
  Los Angeles,米国
- Data Source
  KAKENHI-PROJECT-18390178
[Presentation] 胃がんにおけるメチル化異常とエピジェネティクス疫学.2007
- Author(s)
  湯浅保仁、長崎弘美、秋山好光、他
- Organizer
  第14回日本がん予防学会・第8回日本がん分子疫学研究会・第30回日本がん疫学研究会合同大会
- Place of Presentation
  東京
- Year and Date
  2007-07-13
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] 胃がんにおける転写関連遺伝子GATA4/5のメチル化の解析2007
- Author(s)
  秋山好光、長崎弘美、河本絢子、湯浅保仁
- Organizer
  第14回日本がん予防学会・第8回日本がん分子疫学研究会・第30回日本がん疫学研究会合同大会
- Place of Presentation
  東京
- Year and Date
  2007-07-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390178
[Presentation] 胃がんにおける転写関連遺伝子GATA4/5のメチル化の解析2007
- Author(s)
  秋山好光、長崎弘美、河本絢子、湯浅保仁
- Organizer
  第14回日本がん予防学会・第8回日本がん分子疫学研究会・第30回日本がん疫学研究会合同大会
- Place of Presentation
  東京
- Year and Date
  2007-07-13
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] Epigenetic silencing of SOX2 by DNA methylation in gastric cancers2007
- Author(s)
  大坪武史、秋山好光、湯浅保仁
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] IQGAP2 inactivation through aberrant promoter methylation and promotion of invasion in gastric cancer cells2007
- Author(s)
  Jin S-H, Akiyama Y, Fukamachi H, Yanagihara K, Akashi T, Yuasa Y
- Organizer
  The 8th Korea-Japan Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390178
[Presentation] Loss of transcription factor GA TA-4/-5 by hypermethylation correlated with progression of gastric carcinomas2007
- Author(s)
  Wen X-Y, Akiyama Y, 他
- Organizer
  AACR 97^<th> Annual Meeting
- Place of Presentation
  Los Angeles, 米国
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] Hypermethylation of GATA4 and GATA5 transcription factor genes in gastric cancer.2007
- Author(s)
  Akiyama Y, Yuasa Y
- Organizer
  The 12th Korea-Japan Cancer Research Workshop
- Place of Presentation
  札幌
- Year and Date
  2007-12-22
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] Expression-analysis of microRNA in gastric cancer.2007
- Author(s)
  和田りえ、秋山好光、他
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] Epigenetic silencing of SOX2 by DNA methylation in gastric cancers2007
- Author(s)
  大坪武史、秋山好光、湯浅保仁
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390178
[Presentation] Frequent methylation of GATA4 and GATA5 transcription. factor genes in gastric cancer2007
- Author(s)
  秋山好光、長崎弘美、河本絢子、湯浅保仁
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18390178
[Presentation] Frequent methylation of GATA4 and GATA5 transcription factor genes in gastric cancer2007
- Author(s)
  秋山好光、長崎弘美、河本絢子、湯浅保仁
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390178
[Presentation] Expression analysis of microRNA in gastric cancer2007
- Author(s)
  和田りえ、秋山好光、深町博史、湯浅保仁
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390178
[Presentation] Sox2 inhibits growth of gastric epithelial cell lines through cell cycle arrest and apoptosis2007
- Author(s)
  Otsubo T, Akiyama Y, Yuasa Y.
- Organizer
  AACR (American Association for Cancer research) 97th Annual Meeting
- Place of Presentation
  Los Angeles, 米国
- Year and Date
  2007-04-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390178
[Presentation] Sox2, epigenetically silenced in gastric cancers, inhibits growth through cell cycle arrest and apoptosis.2007
- Author(s)
  Otsubo T, Akiyama Y, 他
- Organizer
  The 8th Korea-Japan Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] GATA4 and GATA5 transcription factor genes were frequently silenced by methylation in gastric cancer.2007
- Author(s)
  Akiyama Y、他
- Organizer
  The 8th Korea-Japan Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-19590340
[Presentation] IQGAP2 inactivation through aberrant promoter methylation and promotion of invasion in gastric cancer cells2007
- Author(s)
  Jin S-H, Akiyama Y, Fukamachi H, Yanagihara K, Akashi T, Yuasa Y
- Organizer
  The 8th Korea-Japan Joint Symposium on Cancer and Ageing Researc
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] From Genes to Molecular Epidemiology2006
- Author(s)
  Yuasa Y, Nagasaki H, Akiyama Y, Imai K, Nakachi K.
- Organizer
  EUROPEAN ENVIRONMENTAL MUTAGEN SOCIETY 36 Annual Meeting
- Place of Presentation
  Praha
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] 胃がんにおけるNotchシグナルとその下流転写因子Hath-1の機能解析.2006
- Author(s)
  湯浅保仁, 関根亜希子, 柳原五吉, 秋山好光
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] 胃がんにおけるBMP-2遺伝子のメチル化の解析2006
- Author(s)
  湯浅保仁, 文賢子, 秋山好光
- Organizer
  第76回日本衛生学会総会
- Place of Presentation
  山口
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] エピジェネティック疫学の現状と予防への応用.2005
- Author(s)
  湯浅保仁, 秋山好光, 今井一枝
- Organizer
  第64回日本癌学会総会シンポジウム
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] Expression changes of Twist1 in diffuse-type gastric cancer cell line of an E-cadherin/p53 deficient mouse model.
- Author(s)
  Sakamoto A, Shimada S, Akiyama Y, Yuasa Y.
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] Epigenetic involvement in a mouse model of E-cadherin/p53-deficient diffuse-type gastric cancer.
- Author(s)
  Shimada S, Akiyama Y, Fukamachi H, Yuasa Y.
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] Altered expression of the histone methyltransferase genes in gastric cancer.
- Author(s)
  Akiyama Y, Koda Y, Nishikawaji T, Shimada S, Deng D, Kim WH, Zhu WG, Yuasa Y.
- Organizer
  4th International Cancer Epigenetics Meeting.
- Place of Presentation
  Yangzhou, China
- Year and Date
  2014-10-17 – 2014-10-20
- Invited
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] Alterations of SETDB2, a histone methyltransferase, in gastric cancers.
- Author(s)
  Nishikawaji T, Akiyama Y, Shimada S, Yuasa Y．
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] Identification of selective inhibitors of muose diffuse-type gastric cancer cells by screening a library of known drugs.
- Author(s)
  Shimada S, Akiyama Y, Fukamachi H, Yuasa Y。
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] Functional analyses of SETDB2, a histone methyltransferase, in gastric cancers.
- Author(s)
  Nishikawaji T, Akiyama Y, Shimada S, Yuasa Y.
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] Function and expression of Twist1 in diffuse-type gastric cancer cell lines of an E-cadherin/p53-deficient mouse model.
- Author(s)
  Sakamoto A, Shimada S, Akiyama Y, Yuasa Y.
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] 胃がんにおけるヒストン修飾関連遺伝子SET7/9の標的遺伝子の解析
- Author(s)
  秋山好光、甲田裕樹、西川路武人、島田周、Woo Ho Kim、Wei-Guo Zhu、湯浅保仁.
- Organizer
  第8回日本エピジェネティクス研究会年会
- Place of Presentation
  東京
- Year and Date
  2014-05-25 – 2014-05-27
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] 胃がんにおけるヒストンメチル化酵素SETDB2発現亢進の役割.
- Author(s)
  西川路武人、秋山好光、島田周、湯浅保仁.
- Organizer
  第8回日本エピジェネティクス研究会年会
- Place of Presentation
  東京
- Year and Date
  2014-05-25 – 2014-05-27
- Data Source
  KAKENHI-PROJECT-24590444
[Presentation] Loss of SET7/9, a histone methyltransferase, in gastric cancers.
- Author(s)
  Akiyama Y, Koda Y, Nishikawaji T, Shimada S, Yuasa Y.
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24590444

1. Tanaka Shinji (30253420)

# of Collaborated Projects: 10 results

# of Collaborated Products: 60 results
2. SHIMADA Shu (20609705)

# of Collaborated Projects: 10 results

# of Collaborated Products: 49 results
3. YUASA Yasuhito (80111558)

# of Collaborated Projects: 6 results

# of Collaborated Products: 75 results
4. FUKAMACHI Hiroshi (70134450)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
5. MORI Masaki (70190999)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. 新部彩乃 (20445448)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
7. TAKIZAWA Touichiro (80323674)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
8. SUGIHARA Kenichi (10171167)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
9. IMAI Kazue (80260230)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
10. KAWANO Tatsuyuki (00186115)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
11. 三宅智 (00332346)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 波多野恵 (50867992)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. NAKAMURA Noriaki (10372442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. AIHARA Arihiro (90451939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. 岩井武尚 (90111591)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 江石義信 (70151959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 大倉康男 (30312284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 熊谷二朗 (80280973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 丸山和夫 (90165944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. Itoh Michiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. AIDA Tomomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 時野隆至

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 落合匠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 工藤篤

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
25. 田辺稔

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
26. 菅波孝祥

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 小野宏晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. 小川康介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 山岡昇司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

AKIYAMA Yosimitsu 秋山 好光

秋山 好光 アキヤマ ヨシミツ

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Co-Researchers

Analysis of tumor microenvironmental alterations in refractory cancer based on histone modification changes and development of novel therapeutic strategiesPrincipal Investigator

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Envolvement of abnormal of SETDB-related histone modification enzyme and tumor immune environment in gastrointestinal cancerPrincipal Investigator

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Molecular pathology of SET-related histone methyltransferase in refractory cancerPrincipal Investigator

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Epigenetic alterations and tumor heterogeneity in gastric cancersPrincipal Investigator

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Clinicopathological significance and epigenetic alterations of miRNAs in gastric cancerPrincipal Investigator

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Epigenetic alterations of GATA transcription factor genes in gastric cancersPrincipal Investigator

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AKIYAMA Yosimitsu 秋山好光

秋山好光アキヤマヨシミツ