Saito Kuniaki 齋藤邦明

… Alternative Names

Researcher Number	80262765
Other IDs
External Links
Affiliation (Current)	2019: 藤田医科大学, 保健学研究科, 教授
Affiliation (based on the past Project Information) *help	2019: 藤田医科大学, 保健学研究科, 教授 2015 – 2018: 藤田保健衛生大学, 保健学研究科, 教授 2016 – 2017: 藤田保健衛生大学, 医療科学部, 教授 2016: 藤田保健衛生大学, 大学院・医療科学部, 教授 2010 – 2014: 京都大学, 医学(系)研究科(研究院), 教授 … More
Review Section/Research Field	Principal Investigator Laboratory medicine / Neurochemistry/Neuropharmacology / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Applied health science / Laboratory medicine / Applied health science Except Principal Investigator Laboratory medicine / Laboratory medicine / Orthopaedic surgery / Circulatory organs internal medicine … More
Keywords	Principal Investigator サイトカイン / AIDS / TNF-α / 脳神経疾患 / バイオマーカー / 痴呆 / ストレス / 抑うつ / 炎症 / 病態検査学 … More Except Principal Investigator Atherosclerosis / TNF-α / サイトカイン / ノックアウトマウス / Cytokine / Apoptosis / tumor necrosis factor-α / Macrophage / encephalomyocarditis virus / 高脂血症 / interferon-γ / knockout mice / 腫瘍 / 慢性関節リウマチ / VCAM-1 / ICAM-1 / 遺伝子解析 / バイオマーカー / IDO / interleukin-1 / マクロファージ / 動脈硬化 / プロテオミクス / トリプトファン代謝 / メタボロミクス / Bone marrow transplantation / Knockout mouse / MCP-1 / IL-6 / pre β HDL / viral myocarditis / GP88 / GP８８ / Soluble Fas / Lipoprotein (a), Lp (a) / Coronary heart disease / 自閉症 / Immunohistochemistry / rhabdomvosis / proteomics / リポ蛋白(a) / ＩＤＯ / 細胞内カルシウム / interleukin-6 / cell adhesion molecules / トランスジェニックマウス / 急性肝障害モデル / 多発性嚢胞腎 / 免疫組織化学 / Polymorphism / IFN-γ / rheumatoid arthritis / LPS / 塩分摂取 / アポリポ蛋白E / がん患者のストレス / MRI / SV2A / 表現型 / 慢性腎臓病 / 急性相反応 / 組織修復 / 臨床検査 / 再灌流障害 / ジェノタイプ / りん酸化タンパク質 / 遺伝型 / 網羅的解析 / retrovirus / allele number / ischemia / Migration / Apo A-IV / 可溶性L-selectin / プロテオーム / Lp(a) lipoprotein / Genotype / Lp(a)リポ蛋白 / レベチラセタム / Phenotype / ガラクトースアミン / ストレスホルモン / STAI / Proliferation / 骨髄移植 / 細胞増殖 / 構造変異性 / statin drugs / 多発性嚢胞腎症 / Knockout Mice / IgA / レトロウィルス / 制限酵素Kpn I / スタチン系薬剤 / 筋障害 / 好中球 / NF-κB / メタボローム / clinical test / うつ病 / アポ(a)表現型 / 臨床プロテオーム / 質量分析 / 制限酵素Swa I / progranulin / pre βHDL / 遺伝子多型性 / インターロイキン2 / NKT細胞免疫療法 / IDO2 / Apolipoprotein E / ウイルス心筋炎 / α-ガラクトシルセラミド / NE-κB / 生存率 / Acute phase reactant / Tissue repair / preβ HDL / 色彩映像 / Apolipoprotein(a) / 血管新生 / INF-α / Rheumatoid arthritis / アポトーシス / 遊走 / immunotherapy / 接着分子 / フェノタイプ / α- ガラクトシルセラミド / 慢性関節リウマチ(RA) / structural heterogeneity / soluble interleukin-2 receptor / POMS / 悪性リンパ腫 / リン酸化 / ウィルス心筋炎 / アポ(a) / 再灌流傷害 / Corobary heart disease / Angiogenesis / 環境因子 / 診断バイオマーカー / Endothelial cell / リアノジン受容体 / 横紋筋融解症 / Proteomics / ELISA / hyperlipidemia / スタチン製剤 / 血管内皮細胞 / 遊走及び増殖 / 接着因子 / 頸動脈内膜剥離術 / inflammatory cell infiltration / 頸動脈プラーク / オミックス解析 / セロトニントランスポーター / biomarker / 心筋虚血 / 増殖 / ケモカイン / トリプトファン / フローサイトメトリー / Lipid-free apolipoprotein / アポ(a)イソ型 / 脳血管障害学 / Fas蛋白 / ストレス緩和 / lymphocyte phenotypes / ＭＲＩ / 炎症細胞浸潤 / Coronary heart desease / reperfusion injury / cytokine / Lipid-free-free apolipoprotein / レトロウイルス / クロモグラニン / CPTII遺伝子 / Allele number / Hyperlipidemia / transgenic mice / TNF / 自閉症スペクトラム障害 / 糖尿病性腎症 / 疾患モデル / macrophage / 腫瘍免疫 / 慢性炎症 / インドールアミン酸素添加酵素 / アポA-IV / IL-1β / アポ(a)遺伝子型 / clinical proteome / 精神薬理学 / chemokines / FACS / Cytokines Less

糖尿病性腎症の代謝変容の解明とその改善を基軸とした発症・進展予防Ongoing
- Principal Investigator
  
  湯澤由紀夫
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Fujita Health University
周産期の栄養および代謝変容が母体、胎児に及ぼす影響Principal InvestigatorOngoing
- Principal Investigator
  
  齋藤邦明
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Fujita Health University
Development of the next-generation diagnosis method for depression by using byomakers based on pathophysiological mechanismOngoing
- Principal Investigator
  
  鍋島俊隆
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Fujita Health University
Analysis of carcinogenesis originated from chronic inflammation in malignant lymphomaOngoing
- Principal Investigator
  
  鶴見寿
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Gifu University
Tryptophan metabolic profile is effective for preemptive medicine in depression symptomsPrincipal Investigator
- Principal Investigator
  
  Saito Kuniaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  Fujita Health University
Omics analysis applicable to preemptive medicine of chronic kidney disease -focusing on comprehensive analysis of phosphorylated proteins-
- Principal Investigator
  
  Nagao Shizuko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Fujita Health University
Increased serum GP88 (Progranulin) concentrations in rheumatoid arthritis.Principal Investigator
- Principal Investigator
  
  SAITO Kuniaki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Fujita Health University
  Kyoto University
Antitumor efficacies of indoleamine 2,3-dioxygenase 2 in lewis lung carcinoma mice model.
- Principal Investigator
  
  Yamamoto Yasuko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Fujita Health University
  Kyoto University
The role of synaptic vesicle protein 2A (SV2A) in the pathophysiology and treatment of Autism spectrum disorders
- Principal Investigator
  
  MORIYA Yuka
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Meijo University
The investigation of immune regulation by IDO in NKT cell-mediated immunotherapy
- Principal Investigator
  
  HOSHI Masato
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity start-up
- Research Field
  
  Laboratory medicine
- Research Institution
  Suzuka University of Medical Science
Increases in Tryptophan-kynurenine pathway metabolism following interferon-induced depressionPrincipal Investigator
- Principal Investigator
  
  SAITO KUNIAKI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kyoto University
Studies on thescale for stress induced emotional changesPrincipal Investigator
- Principal Investigator
  
  SAITO Kuniaki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied health science
- Research Institution
  Kyoto University
Role of indoleamine-2,3-dioxygenase in atherosclerotic carotid artery stenosis
- Principal Investigator
  
  SUYAMA Kazuhiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagasaki University
Screening and gene analysis for the protection from muscle damage by statin drugs
- Principal Investigator
  
  SEISHIMA Mitsuru
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
The pathophysiologic role of indoleamine 2, 3-dioxygenase in viral infectious diseasesPrincipal Investigator
- Principal Investigator
  
  SAITOU Kuniaki
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kyoto University
Development of device using color images to reduce stress in cancer and/or other chronic disease patients.
- Principal Investigator
  
  SAITO Yumi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Fundamental nursing
- Research Institution
  Kyoto University
Study on the mechanism of rhabdomyosis induced by statins and gene analysis of patients with rhalxiomyasis
- Principal Investigator
  
  TAKEMURA Masao, 和田久泰
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
Study on analytical system for the etiology of autoimmune disease using two-dimensional nano LC/MS
- Principal Investigator
  
  SEISHIMA Mitsuru
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
マウス骨髄移植技術を用いた肝不全発症機構の解明とその臨床応用に関する研究
- Principal Investigator
  
  YAMADA Yasuhiro
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Gifu University
The role of proinflammatory cytokines in the generation of myocardial ischemia/reperfusion injury
- Principal Investigator
  
  WADA Hisayasu
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Gifu University
Proteome analysis of human macrophage cells associated with atherosclerosis
- Principal Investigator
  
  FUJII Hidehiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
Study on the mechanism of atherosclerotic lesion formation using cytokine-knockout mouse
- Principal Investigator
  
  SEISHIMA Mitsuru
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
A mechanism of HIV-related dementia complex - relation between TNF-α and dementia -Principal Investigator
- Principal Investigator
  
  SAITO Kuniaki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Gifu University
The method for determination of serum lipid-free apolipoprotein concentration and its clinical application
- Principal Investigator
  
  SEISHIMA Mitsuru
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
A study of the role of cytokines in the development of atherosclerosis using double knockout mice
- Principal Investigator
  
  WADA Hisayasu, 藤井秀比古
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Gifu University
TNF-αノックアウトマウスを用いたエイズ痴呆コンプレックス発症機構に関する研究Principal Investigator
- Principal Investigator
  
  斉藤邦明
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Gifu University
The role of proinflammatory cytokines in the development and progression of viral myocarditis
- Principal Investigator
  
  WADA Hisayasu
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Gifu University
Significance of soluble Fas and its related cytokines in serum of rheumatoid arthritis patients.
- Principal Investigator
  
  TAKEUCHI Shoji
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Gifu University
脳神経系疾患における組織修復と各種アポタンパク合成との関係Principal Investigator
- Principal Investigator
  
  斉藤邦明
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
Study on the role of Lp (a) as an acute phase reactant and on the effects on arterial endothelial and smooth muscle cells.
- Principal Investigator
  
  NOMA Akio
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
Basic studies of immunotherapy in relation to the serum soluble interleukin-2 receptor determination in patients with rheumatoid arthritis
- Principal Investigator
  
  TAKEUCHI Shoji
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Gifu University
Study on apo A-IV polymorphism in patients with hyperlipidemia.
- Principal Investigator
  
  SEISHIMA Mitsuru
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
Study on structural heterogeneity of Lp(a) and its clinical significance.
- Principal Investigator
  
  MAKINO Kazuhiko
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2006 Other

All Journal Article Presentation Book

[Book] :Tumor Necrosis factor2014
- Author(s)
  Murakami Y, Imamura Y, Mitani S, Hoshi M, Arioka Y, Yamamoto Y, Seiyama A, Saito K.
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-23390149
[Book] Tumor Necrosis factor
- Author(s)
  Murakami Y, Imamura Y, Mitani S, Hoshi M, Arioka Y, Yamamoto Y, Seiyama A, Saito K
- Publisher
  Nova Science Publishers, Inc
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] Systemic circulation and bone recruitment of osteoclast precursors tracked by using fluorescent imaging techniques2018
- Author(s)
  Sakata M, Ohigashi I, Takahama Y.
- Journal Title
  
  J Immunol.
  
  Volume: 200 Pages: 1382-1388
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08884, KAKENHI-PROJECT-15K21190, KAKENHI-PROJECT-15K06843, KAKENHI-PROJECT-26670486, KAKENHI-PROJECT-26670476, KAKENHI-PROJECT-25253032, KAKENHI-PROJECT-25670408, KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-23592615, KAKENHI-PROJECT-24591475, KAKENHI-PROJECT-24890270, KAKENHI-ORGANIZER-24111001
[Journal Article] Neurotrophic Phenylbutenoid Dimers Isolated from Zingiber purpureum Enhance Adult Hippocampal Neurogenesis in Olfactory Bulbectomized Mice.2018
- Author(s)
  Mishima T, Deshimaru M, Watanabe T, Kubota K, Kinoshita-Kawada M, Yuasa-Kawada J, Takasaki K, Uehara Y, Jinno S, Iwasaki K, Tsuboi Y
- Journal Title
  
  Neuroscience Lett.
  
  Volume: 666 Pages: 96-101
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860678, KAKENHI-PROJECT-15K11324, KAKENHI-PROJECT-16K07003, KAKENHI-PROJECT-23593036, KAKENHI-PROJECT-24591680, KAKENHI-PROJECT-24890270, KAKENHI-PROJECT-21300215, KAKENHI-PROJECT-23592501, KAKENHI-PROJECT-22590029
[Journal Article] PKCδ Knockout Mice Are Protected from Dextromethorphan-Induced Serotonergic Behaviors in Mice: Involvements of Downregulation of 5-HT1A Receptor and Upregulation of Nrf2-Dependent GSH Synthesis2018
- Author(s)
  Tran HQ, Lee Y, Shin EJ, Jang CG, Jeong JH, Mouri A, Saito K, Nabeshima T, Kim HC.
- Journal Title
  
  Molecular Neurobiology
  
  Volume: 印刷中
- DOI
  10.1007/s12035-018-0938-7
- Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-17H04252
[Journal Article] Association between naturally occurring anti-amyloid β autoantibodies and medial temporal lobe atrophy in Alzheimer's disease.2017
- Author(s)
  .Kimura A, Takemura M, Saito K, Yoshikura N, Hayashi Y, Inuzuka T.
- Journal Title
  
  J Neurol Neurosurg Psychiatry
  
  Volume: 88 Pages: 126-131
- DOI
  10.1136/jnnp-2016-313476
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-26461290, KAKENHI-PROJECT-26860664, KAKENHI-PROJECT-15K09337, KAKENHI-PROJECT-26460861
[Journal Article] Effect of water-immersion restraint stress on tryptophan catabolism through the kynurenine pathway in rat tissues2017
- Author(s)
  Ohta Y , Kubo H , Yashiro K , Ohashi K , Tsuzuki Y , Wada N , Yamamoto Y , Saito, K
- Journal Title
  
  JOURNAL OF PHYSIOLOGICAL SCIENCES
  
  Volume: 67 Pages: 361-372
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03086
[Journal Article] Absence of kynurenine 3-monooxygenase reduces mortality of acute viral myocarditis in mice.2017
- Author(s)
  Kubo H, Hoshi M, Mouri A, Tashita C, Yamamoto Y, Nabeshima T, Saito K.
- Journal Title
  
  Immunol Lett.
  
  Volume: 181 Pages: 94-100
- DOI
  10.1016/j.imlet.2016.11.012
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-26460675, KAKENHI-PROJECT-26860376, KAKENHI-PROJECT-16K10195
[Journal Article] Association between increased serum GP88 (progranulin) concentrations and prognosis in patients with malignant lymphomas.2017
- Author(s)
  Yamamoto Y, Goto N, Takemura M, Yamasuge W, Yabe K, Takami T, Miyazaki T, Takeuchi T, Shiraki M, Shimizu M, Adachi S, Saito K, Shibata Y, Nakamura N, Hara T, Serrero G, Saito K, Tsurumi H.
- Journal Title
  
  Clin Chim Acta.
  
  Volume: 473 Pages: 139-146
- DOI
  10.1016/j.cca.2017.07.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09920, KAKENHI-PROJECT-17H07222
[Journal Article] Increased cerebrospinal fluid progranulin correlates with interleukin-6 in the acute phase of neuromyelitis optica spectrum disorder2017
- Author(s)
  Kimura A, Takemura M, Saito K, Serrero G, Yoshikura N, Hayashi Y, Inuzuka T.
- Journal Title
  
  J Neuroimmunol.
  
  Volume: 305 Pages: 175-181
- DOI
  10.1016/j.jneuroim.2017.01.006
- Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-26461290, KAKENHI-PROJECT-26860664, KAKENHI-PROJECT-15K09337, KAKENHI-PROJECT-26460861
[Journal Article] Kynurenine 3-monooxygenase is implicated in antidepressants-responsive depressive-like behaviors and onoaminergic dysfunctions.2017
- Author(s)
  Tashiro T , Murakami Y , Mouri A , Imamura Y, Nabeshima T, Yamamoto, Y , Saito, K
- Journal Title
  
  Behavioral Brain Research
  
  Volume: 317 Pages: 279-285
- DOI
  10.1016/j.bbr.2016.09.050
- Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-24592734, KAKENHI-PROJECT-26460240, KAKENHI-PROJECT-26460675, KAKENHI-PROJECT-26860368, KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-16K08948, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17H04364
[Journal Article] Effect of water-immersion restraint stress on tryptophan catabolism through the kynurenine pathway in rat tissues2017
- Author(s)
  Ohta, Y ; Kubo, H ; Yashiro, K ; Ohashi, K ; Tsuzuki, Y ; Wada, N ; Yamamoto, Y ; Saito, K
- Journal Title
  
  JOURNAL OF PHYSIOLOGICAL SCIENCES 4.巻 67 5.発行年 2017
  
  Volume: 4 Pages: 361-372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460675
[Journal Article] Depressive symptoms as a side effect of Interferon-α therapy induced by induction of indoleamine 2,3-dioxygenase 12016
- Author(s)
  Murakami Y, Ishibashi T, Tomita E, Imamura Y, Tashiro T, Watcharanurak K, Nishikawa M, Takahashi Y, Takakura Y, Mitani S, Fujigaki H, Ohta Y, Kubo H, Mamiya T, Nabeshima T, Kim HC, Yamamoto Y, Saito K.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Pages: 1-12
- DOI
  10.1038/srep29920
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-15H04100, KAKENHI-PROJECT-24592734, KAKENHI-PROJECT-26460240, KAKENHI-PROJECT-26460675, KAKENHI-PROJECT-26860368, KAKENHI-PROJECT-16K08948
[Journal Article] L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences2016
- Author(s)
  Fujigaki H, Yamamoto Y, Saito K
- Journal Title
  
  NEUROPHARMACOLOGY
  
  Volume: 印刷中 Pages: 264-274
- DOI
  10.1016/j.neuropharm.2016.01.011
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860379, KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-26460675
[Journal Article] Prognostic value of the combination of serum l-kynurenine level and indoleamine 2,3-dioxygenase mRNA expression in acute myeloid leukemia.2016
- Author(s)
  Hara T, Matsumoto T, Shibata Y, Nakamura N, Nakamura H, Ninomiya S, Kitagawa J, Nannya Y, Shimizu M, Ito H, Saito K, Tsurumi H.
- Journal Title
  
  Leuk Lymphoma.
  
  Volume: 13 Pages: 1-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03086
[Journal Article] L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences. Neuropharmacology.2016
- Author(s)
  Fujigaki H, Yamamoto Y, Saito K.
- Journal Title
  
  j.neuropharm.
  
  Volume: S0028-3908(16) Pages: 30011-9
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03086
[Journal Article] Effects of various phytochemicals on indoleamine 2,3-dioxygenase 1 activity: galanal is a novel, competitive inhibitor of the enzyme.2014
- Author(s)
  Yamamoto R, Yamamoto Y, Imai S, Fukutomi R, Ozawa Y, Abe M, Matuo Y, Saito K
- Journal Title
  
  PLoS One
  
  Volume: 12;9(2)
- DOI
  10.1371/journal.pone.0088789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] Indoleamine 2,3-dioxygenase 1 is upregulated in activated microglia in mice cerebellum during acute viral encephalitis.2014
- Author(s)
  Taguchi A, Niwa M, Hoshi M, Saito K, Masutani T, Hisamatsu K, Kobayashi K, Hatano Y, Tomita H, Hara A
- Journal Title
  
  Neurosci Lett.
  
  Volume: 3564 Pages: 120-5
- DOI
  10.1016/j.neulet.2014.01.051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890270, KAKENHI-PROJECT-26860376
[Journal Article] Induction of HBsAg-specific cytotoxic T lymphocytes can be up-regulated by the inhibition of indoleamine 2, 3-dioxygenase activity2014
- Author(s)
  Ito H, Ando T, Ando K, Ishikawa T, Saito K, Moriwaki H, Seishima M
- Journal Title
  
  Immunology
- DOI
  10.1111/imm.12274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24659361
[Journal Article] Oral Porphyromonas gingivalis translocates to liver and regulates hepatic glycogen synthesis through the Akt/GSK-3b signaling pathway.2014
- Author(s)
  Ohtaki H, Ito H, Ando K, Ishikawa T, Hoshi M, Ando T, Takamatsu M, Hara A, Moriwaki H, Saito K, Seishima M
- Journal Title
  
  Biochimica et Biophysica Acta
  
  Volume: S0925-4439(14) Pages: 102-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890270, KAKENHI-PROJECT-12J02846, KAKENHI-PROJECT-25460862, KAKENHI-PROJECT-25462918
[Journal Article] Kynurenine production mediated by indoleamine 2,3-dioxygenase aggravates liver injury in HBV-specific CTL-induced fulminant hepatitis.2014
- Author(s)
  Ohtaki H, Ito H, Ando K, Ishikawa T, Hoshi M, Ando T, Takamatsu M, Hara A, Moriwaki H, Saito K, Seishima M
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1842(9) Pages: 1464-71
- DOI
  10.1016/j.bbadis.2014.04.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24659361, KAKENHI-PROJECT-26860376
[Journal Article] Effects of indoleamine 2,3-dioxygenase deficiency on high-fat diet-induced hepatic inflammation.2013
- Author(s)
  Nagano J, Shimizu M, Hara T, Shirakami Y, Kochi T, Nakamura N, Ohtaki H, Ito H, Tanaka T, Tsurumi H, Saito K, Seishima M, Moriwaki H
- Journal Title
  
  PLoS One
  
  Volume: 9;8(9)
- DOI
  10.1371/journal.pone.0073404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-25460987, KAKENHI-PROJECT-25460988
[Journal Article] [Indoleamine 2,3-dioxygenase 1 modulates the immuneresponse; the new therapeutic targets of this drug].2013
- Author(s)
  Yamamoto Y, Murakami Y, Hoshi M, Saito K.
- Journal Title
  
  Nihon Yakurigaku Zasshi
  
  Volume: 142(2) Pages: 85-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890270
[Journal Article] Remarkable role of indoleamine 2,3-dioxygenase and tryptophan metabolites in infectious diseases : potential role in macrophage-mediated inflammatory diseases2013
- Author(s)
  Murakami Y, Hoshi M, Imamura Y, Arioka Y, Yamamoto Y, Saito K
- Journal Title
  
  Mediators of Inflammation
  
  Volume: 2013 Pages: 391984-391984
- DOI
  10.1155/2013/391984
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-23790621, KAKENHI-PROJECT-24592734, KAKENHI-PROJECT-24890270
[Journal Article] Acquired resistance of leukemic cells to AraC is associated with the upregulation of aldehyde dehydrogenase 1 family member A2.2013
- Author(s)
  Kawasoe M, Yamamoto Y, Okawa K, Funato T, Takeda M, Hara T, Tsurumi H, Moriwaki H, Arioka Y, Takemura M, Matsunami H, Markey SP, Saito K.
- Journal Title
  
  Exp Hematol.
  
  Volume: 41(7) Pages: 597-603
- DOI
  10.1016/j.exphem.2013.03.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] IDO1 plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice2013
- Author(s)
  Takamatsu M, Hirata A, Ohtaki H, Hoshi M, Hatano Y, Tomita H, Kuno T, Saito K, Hara A
- Journal Title
  
  Journal of Immunology
  
  Volume: 15;191(6) Pages: 3057-3064
- DOI
  10.4049/jimmunol.1203306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24790381, KAKENHI-PROJECT-24890270
[Journal Article] Species and cell types difference in tryptophan metabolism2013
- Author(s)
  Murakami Y, Saito K
- Journal Title
  
  Int J Tryptophan Res
  
  Volume: 21;6 Pages: 47-54
- DOI
  10.4137/ijtr.s11558
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] Pre-administration of L-tryptophan improved ADR-induced early renal failure in mice.2012
- Author(s)
  Arioka Y
- Journal Title
  
  Life Sci.
  
  Volume: 59 Pages: 100-106
- DOI
  10.1016/j.lfs.2012.06.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390179, KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24890270
[Journal Article] Posttranslational modification of indoleamine 2, 3-dioxygenase2012
- Author(s)
  Fujigaki H, Seishima M, Saito K
- Journal Title
  
  Anal Bioanal Chem
  
  Volume: 403(7) Pages: 1777-82
- DOI
  10.1007/s00216-012-5946-2
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] -Epigallocatechin gallate inhibits the expression of indoleamine 2,3-dioxygenase in human colorectal cancer cells2012
- Author(s)
  Ogawa K, Hara T, Shimizu M, Nagano J, Ohno T, Hoshi M, Ito H, Tsurumi H, Saito K, Seishima M, Moriwaki H
- Journal Title
  
  Oncol Lett
  
  Volume: 4(3) Pages: 546-550
- URL
  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673646/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890270
[Journal Article] 遺伝子検査に有用なインターネット活用2012
- Author(s)
  齋藤邦明
- Journal Title
  
  Medical Technology
  
  Volume: 40 Pages: 1580-1580
- Data Source
  KAKENHI-PROJECT-23650417
[Journal Article] High susceptibility to lipopolysaccharide-induced lethal shock in encephalomyocarditis virus-infected mice2012
- Author(s)
  Ohtaki H
- Journal Title
  
  Sci Rep
  
  Volume: 2 Pages: 367-367
- DOI
  10.1038/srep00367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790787, KAKENHI-PROJECT-24890270
[Journal Article] 健康管理におけるオミックス解析の意義2012
- Author(s)
  村上由希、松尾雄志、齋藤邦明
- Journal Title
  
  医療と検査機器試薬
  
  Volume: 35 Pages: 331-334
- Data Source
  KAKENHI-PROJECT-23650417
[Journal Article] Epigallocatechin gallate inhibits the expression of indoleamine 2, 3-dioxygenase in human colorectal cancer cells2012
- Author(s)
  Ogawa K, Hara T, Shimizu M, Nagano J, Ohno T, Hoshi M, Ito H, Tsurumi H, Saito K, Seishima M, Moriwaki H
- Journal Title
  
  Oncol Lett
  
  Volume: 4(3) Pages: 546-550
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] Posttranslational modification of indoleamine 2,3-dioxygenase2012
- Author(s)
  Fujigaki H, Seishima M, Saito K
- Journal Title
  
  Anal Bioanal Chem
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] Suppression of azoxymethane-induced colonic preneoplastic lesions in rats by 1-methyltryptophan, an inhibitor of indoleamine 2,3-dioxygenase2012
- Author(s)
  Ogawa K, Hara T, Shimizu M, Ninomiya S, Nagano J, Sakai H, Hoshi M, Ito H, Tsurumi H, Saito K, Seishima M, Tanaka T, Moriwaki H
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Pages: 951-8
- DOI
  10.1111/j.1349-7006.2012.02237.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590838, KAKENHI-PROJECT-24890270
[Journal Article] L-tryptophan-kynurenine pathway metabolites regulate type I IFNs of acute viral myocarditis in mice.2012
- Author(s)
  Hoshi M
- Journal Title
  
  J Immunol.
  
  Volume: 188 Pages: 3980-3987
- DOI
  10.4049/jimmunol.1100997
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390179, KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-23790787, KAKENHI-PROJECT-24890270
[Journal Article] L-Tryptophan-kynurenine pathway metabolites regulate type I IFNs of acute viral myocarditis in mice2012
- Author(s)
  Hoshi M, Yamamoto Y, Saito K, 他4名
- Journal Title
  
  J Immunol
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] Studies on tissue and cellular distribution of indoleamine 2,3-dioxygenase 2: the absence of IDO1 upregulates IDO2 expression in the epididymis2012
- Author(s)
  Fukunaga M, Yamamoto Y, Kawasoe M, Arioka Y, Murakami Y, Hoshi M, Saito K
- Journal Title
  
  J Histochem Cytochem.
  
  Volume: 60(11) Pages: 854-60
- DOI
  10.1369/0022155412458926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24890270
[Journal Article] Inhibition of increased indoleamine 2,3-dioxygenase activity attenuates Toxoplasma gondii replication in the lung during acute infection2012
- Author(s)
  Murakami Y, Hoshi M, Hara A, Takemura M, Arioka Y, Yamamoto Y, Matsunami H, Funato T, Seishima M, Saito K
- Journal Title
  
  Cytokine.
  
  Volume: 59(2) Pages: 245-51
- DOI
  10.1016/j.cyto.2012.04.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24890270
[Journal Article] 遺伝子検査に有用なインターネット活用2012
- Author(s)
  斉藤邦明
- Journal Title
  
  Medical Technology
  
  Volume: 40 Pages: 1580-1580
- Data Source
  KAKENHI-PROJECT-23650417
[Journal Article] Indoleamine 2,3-dioxygenase in tumor tissue indicates prognosis in patients with diffuse large B-cell lymphoma treated with R-CHOP2011
- Author(s)
  Ninomiya S, Hara T, Saito K, 他13名
- Journal Title
  
  Ann Hematol
  
  Volume: 90(4) Pages: 409-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Indoleamine 2, 3-dioxygenase in tumor tissue indicates prognosis in patients with diffuse large B-cell lymphoma treated with R-CHOP2011
- Author(s)
  Ninomiya S, Hara T, Tsurumi H, Hoshi M, Kanemura N, Goto N, Kasahara S, Shimizu M, Ito H, Saito K, Hirose Y, Yamada T, Takahashi T, Seishima M, Takami T, Moriwaki H.
- Journal Title
  
  Ann Hematol.
  
  Volume: 90(4) Pages: 409-16
- DOI
  10.1007/s00277-010-1093-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] L-tryptophan-mediated enhancement of susceptibility to nonalcoholic fatty liver disease is dependent on the mammalian target of rapamycin2011
- Author(s)
  Osawa Y, Kanamori H, Seki E, Hoshi M, Ohtaki H, Yasuda Y, Ito H, Suetsugu A, Nagaki M, Moriwaki H, Saito K, Seishima M
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 34800-34808
- DOI
  10.1074/jbc.m111.235473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J06850, KAKENHI-PROJECT-20390167, KAKENHI-PROJECT-21390179
[Journal Article] Ability of IDO to attenuate liver injury in alpha-galactosylceramide-induced hepatitis model2011
- Author(s)
  Ito H, Hoshi M, Saito K, 他
- Journal Title
  
  J Immunol
  
  Volume: 185(8) Pages: 4554-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] バイオリソース有効活用：RECHSにおける仕組みづくりの重要性2011
- Author(s)
  松尾雄志、松波英寿、竹村正男、齋藤邦明
- Journal Title
  
  臨床病理
  
  Volume: 59 Pages: 1124-1130
- Data Source
  KAKENHI-PROJECT-23650417
[Journal Article] Ability of IDO to attenuate liver in juryin alpha-galactosylceramide-in duced hepatitis model2010
- Author(s)
  Ito H, Hoshi M, Ohtaki H, Taguchi A, AndoK, Ishikawa T, Osawa Y, Hara A, Moriwaki H, Saito K, Seishima M.
- Journal Title
  
  J Immunol.
  
  Volume: 185(8) Pages: 4554-60
- DOI
  10.4049/jimmunol.0904173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Serum concentration of L-kynureninepredicts the clinical outcome of patientswith diffuse large B-cell lymphoma treated with R-CHOP2010
- Author(s)
  Yoshikawa T, Hara T, Tsurumi H, Goto N, Hoshi M, Kitagawa J, Kanemura N, Kasahara S, Ito H, Takemura M, Saito K, Seishima M, Takami T, Moriwaki H.
- Journal Title
  
  Eur J Haematol.
  
  Volume: 84(4) Pages: 304-309
- DOI
  10.1111/j.1600-0609.2009.01393.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] 映像選択システムを用いた感情・ストレスに対する色彩映像効果の解析2010
- Author(s)
  石山瑠理、齋藤ゆみ
- Journal Title
  
  健康科学(京都大学医学部保健学科紀要) 6巻
  
  Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390541
[Journal Article] The absence of IDO upregulates type I IFN production, resulting in suppression of viral replication in the retrovirus-infected mouse2010
- Author(s)
  Hoshi M, Saito K, Hara A, Taguchi A, OhtakiH, Tanaka R, Fujigaki H, Osawa Y, TakemuraM, Matsunami H, Ito H, Seishima M.
- Journal Title
  
  J Immunol.
  
  Volume: 185(6) Pages: 3305-12
- DOI
  10.4049/jimmunol.0901150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] 映像選択システムを用いた感情・ストレスに対する色彩映像効果の解析2010
- Author(s)
  石山瑠理, 齋藤ゆみ
- Journal Title
  
  健康科学 (京都大学医学部保健学科紀要) 6
  
  Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390541
[Journal Article] 好みの単色彩光による感情刺激効果2010
- Author(s)
  齋藤ゆみ、羅越、笹山哲、齋藤邦明、豊川博己
- Journal Title
  
  日本補完代替医療学会
  
  Volume: 7 Pages: 103-111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390541
[Journal Article] 好みの単色彩光による感情刺激効果2010
- Author(s)
  齋藤ゆみ、羅越、笹山哲、齋藤邦明、豊川博己
- Journal Title
  
  日本補完代替医療学会 7巻
  
  Pages: 103-111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390541
[Journal Article] The absence of IDO upregulates type I IFN production, resulting in suppression of viral replication in the retrovirus-infected mouse2010
- Author(s)
  Hoshi M, Saito K, 他10名
- Journal Title
  
  J Immunol
  
  Volume: 185(6) Pages: 3305-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Changes in serum tryptophan catabolism as an indicator of disease activity in adult T-cell leukemia/lymphoma2009
- Author(s)
  Hoshi M, Ito H, Fujigaki H, Takemura M, Takahashi T, Tomita E, Ohyama M, Tanaka R, Ohtaki H, Saito K, Seishima M.
- Journal Title
  
  LeukLymphoma.
  
  Volume: 50(8) Pages: 1372-1374
- DOI
  10.1080/10428190903045393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Marked increases in hippocampal neuron indoleamine 2, 3-dioxygenase via IFN-gamma-independent pathway following2009
- Author(s)
  Hoshi M, Saito K, Murakami, 他7名
- Journal Title
  
  Neurosci Res. 63
  
  Pages: 194-198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Statin-induced Ca2+release wasincreased in B lymphocytes in patients who showed elevated serum creatine kinase during statin treatment.2009
- Author(s)
  Hattori T, Saito K, Takemura M, Ito H, Ohta H, Wada H, Sei Y, Kawamura M,Seishima M.
- Journal Title
  
  J Atheroscler Thromb
  
  Volume: 16 Pages: 870-7
- URL
  https://www.jstage.jst.go.jp/browse/jat
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390179
[Journal Article] Marked increases in hippocampal neuron indoleamine 2, 3-dioxygenase via IFN-gamma-independent pathway following transient global ischemia in mouse2009
- Author(s)
  Hoshi M, Saito K, Murakami Y, Taguchi A, Fujigaki H, Tanaka R, Takemura M, Ito H, Hara A, Seishima M.
- Journal Title
  
  Neurosci Res.
  
  Volume: 63(3) Pages: 194-198
- DOI
  10.1016/j.neures.2008.12.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Interaction between LPS-induced NO production and IDO activity in mouse peritoneal cells in the presence of activated Valpha14 NKT cells2009
- Author(s)
  Ohtaki H, Ito H, Ando K, Ishikawa T, HoshiM, Tanaka R, Osawa Y, Yokochi T, MoriwakiH, Saito K, Seishima M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 389(2) Pages: 229-34
- DOI
  10.1016/j.bbrc.2009.08.120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] 色彩映像の心理的効果-映像選択システムの併用による色彩映像の感情刺激効果の検討2008
- Author(s)
  齋藤ゆみ, 笹山哲
- Journal Title
  
  日本補完代替医療学会誌 5
  
  Pages: 225-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390541
[Journal Article] Localization and spatiotemporal expression of IDO following transient forebrain ischemia in gerbils.2008
- Author(s)
  Taguchi A, Hara A, Saito K, 他4名
- Journal Title
  
  Brain Res. 1217
  
  Pages: 78-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] 色彩映像の心理的効果-映像選択システムの併用による色彩映像の感情刺激効果の検討2008
- Author(s)
  齋藤ゆみ、笹山哲、菅佐和子、池本正生
- Journal Title
  
  日本補完代替医療学会誌 5巻
  
  Pages: 225-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390541
[Journal Article] Nitration and inactivation of IDO by peroxynitrite.2006
- Author(s)
  Fujigaki H, Saito K, Lin F, Fujigaki S, Takahashi K, Martin BM, Chen CY, Masuda J, Kowalak J, Takikawa O, Seishima M, Markey SP.
- Journal Title
  
  The Journal of Immunology 176(1)
  
  Pages: 372-379
- Data Source
  KAKENHI-PROJECT-17390161
[Journal Article] The signal transducer and activator of trenscription 1α and interferon regulatory factor 1are not essential for the induction of indoleamine 2,3-dioxygenase by lipopolysaccharide : involvement of p38 mitogen-activated protein kinase and nuclear factor-κ B pathways, and synergistic effect of several proinflammatory cytokines.2006
- Author(s)
  Fujigaki H, Saito K, Fujigaki S, Takemura M, Sudo K, lshiguro H, Seishima M.
- Journal Title
  
  The Journal of Biochemistry 139(4)
  
  Pages: 655-662
- Data Source
  KAKENHI-PROJECT-18590525
[Journal Article] Nitration and inactivation of indoeamine 2,3-dioxygenase by peroxynitrite2006
- Author(s)
  Fujigaki H, Saito K, Seishima M他
- Journal Title
  
  J.Immunol 176
  
  Pages: 372-379
- Data Source
  KAKENHI-PROJECT-17390161
[Journal Article] The signal transducer and activity of transcription 1a and interferon regulatory factor 1 are not essential for the induction of indoleamine 2,3-dioxygenase by lipopolysaccharide2006
- Author(s)
  Fujigaki H, Saito K, Seishima M他
- Journal Title
  
  J.Biochem. (In Press)
- Data Source
  KAKENHI-PROJECT-17390161
[Presentation] 先制医療の実現のために～次世代創薬・診断薬開発～2017
- Author(s)
  齋藤邦明
- Organizer
  臨床検査薬協会・技術委員会総会
- Place of Presentation
  ヒューリックカンファレンスルーム(東京
- Invited
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] Depressive symptoms and L-Tryptophan -Kynurenine pathway metabolism focus on neuro-inflammation.2017
- Author(s)
  Kuniaki Saito
- Organizer
  The 5th Congress of Asian College pof Neuropsychopharmacology( 2017.4.27-29, Indonesia)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] 周産期における抑うつにおけるユビキチン化セロトニントランスポーターの変化2016
- Author(s)
  毛利彰宏、椎野智子、勅使河原知明、山本康子、野田幸裕、尾崎紀夫、齋藤邦明、鍋島俊隆　「
- Organizer
  第56回日本臨床化学会学術大会
- Place of Presentation
  熊本県民交流館パレア(熊本）
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] 周産期における抑うつにおけるトリプトファン代謝関連分子の変化2016
- Author(s)
  勅使河原知明、久保緋紗子、毛利彰宏、鍋島俊隆、尾崎紀夫、山本康子、齋藤邦明
- Organizer
  第56回日本臨床化学会学術大会
- Place of Presentation
  熊本県民交流館パレア(熊本）
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] 周産期における抑うつにおけるトリプトファン代謝関連分子の変化2016
- Author(s)
  勅使河原知明、久保緋紗子、毛利彰宏、鍋島俊隆、尾崎紀夫、山本康子、齋藤邦明
- Organizer
  第56回日本臨床化学会学術大会
- Place of Presentation
  熊本県民交流館パレア(熊本）
- Data Source
  KAKENHI-PROJECT-26460675
[Presentation] 健常時からの暦年的バイオバンクの活用 -代謝変容に着目したバイオマーカー検索-2015
- Author(s)
  斉藤邦明
- Organizer
  第55回日本臨床化学会年次学術集会
- Place of Presentation
  大阪大学コンベンションセンター（吹田市）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] 先制医療を実現するためのバイオバンク2015
- Author(s)
  斉藤邦明
- Organizer
  第62回日本臨床検査医学会学術集会
- Place of Presentation
  長良川国際会議場（岐阜）
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] 先制医療実現のために　ー不健康を科学するー2015
- Author(s)
  斉藤邦明
- Organizer
  日本健康科学会第31回学術集会・次期学術集会長講演
- Place of Presentation
  ホテルグランドヒル市ヶ谷（東京）
- Year and Date
  2015-08-21
- Invited
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] Increased serum GP88(progranulin) concentration in rheumatoid arthritis.2015
- Author(s)
  Yamamoto　Y, Saito K
- Organizer
  IFCC Paris
- Place of Presentation
  Le Palais des Congres de paris(France)
- Year and Date
  2015-06-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670278
[Presentation] RA患者におけるバイオマーカー GP88の検討2015
- Author(s)
  竹村正男、佐藤正夫、山本康子、斎藤邦明
- Organizer
  第27回中部リウマチ学会
- Place of Presentation
  ウインクあいち（名古屋市）
- Year and Date
  2015-09-04
- Data Source
  KAKENHI-PROJECT-26670278
[Presentation] The role of L-tryptophan metabolism via indoleamine 2,3-dioxygenase on cytokine-induced depressive symptoms2015
- Author(s)
  Saito K
- Organizer
  ISTRY conference Symposium Pathology III
- Place of Presentation
  Grand Rapids（ USA）
- Year and Date
  2015-09-16
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] 関節リウマチ症例における血清Progranulinの測定2015
- Author(s)
  山本康子, 竹村正男, 佐藤正夫, 斉藤邦明
- Organizer
  第55回日本臨床化学会
- Place of Presentation
  大阪大学コンベンションセンター（吹田市）
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-26670278
[Presentation] Recent advances of biomarker discovery in biological fluids by using Mass Spectrometry2013
- Author(s)
  Saito,K
- Organizer
  8th International Conference of Clinical Laboratory Automation
- Place of Presentation
  Seoul, Korea(招待講演)
- Data Source
  KAKENHI-PROJECT-23650417
[Presentation] Labdane-type diterpene, constituent from myoga which are traditional Japanese food inhibit enzyme activity and gene expression of indoleamine 2,3-dioxygenase 12013
- Author(s)
  S Imai, R Yamamoto, Y Yamamoto, Y Katayanagi, R Fukutomi, M Abe, Y Ozawa, K Saito
- Organizer
  15thInternational Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-23390149
[Presentation] 免疫調節因子インドールアミン 2,3-ジオキシゲナーゼ1の新規阻害剤探索：フィトケミカルを中心として2013
- Author(s)
  山本梨絵, 山本康子, 今井伸二郎, 松尾雄志, 小澤好夫, 阿部雅子, 福富竜太, 斉藤邦明
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23390149
[Presentation] 免疫調節因子インドールアミン 2, 3-ジオキシゲナーゼ1の新規阻害剤探索 : フィトケミカルを中心として2013
- Author(s)
  山本梨絵, 山本康子, 今井伸二郎, 松尾雄志, 小澤好夫, 阿部雅子, 福富竜太, 斉藤邦明
- Organizer
  第36回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23390149
[Presentation] 疾患メタボローム・疾患プロテオミクス解析2013
- Author(s)
  斉藤邦明
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-23390149
[Presentation] Recent advances of biomarker discovery in biological fluids by using Mass Spec trometry2013
- Author(s)
  Saito, K
- Organizer
  8th International Conference of Clinica l Laboratory Automation
- Place of Presentation
  Seoul, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-23390149
[Presentation] Labdane-type diterpene, constituent from myoga which are traditional Japanese food inhibit enzyme activity and gene expression of in doleamine 2, 3-dioxygenase 12013
- Author(s)
  Imai, R Yamamoto, Y Yamamoto, Y Katayan agi, R Fukutomi, M Abe, Y Ozawa, K Saito
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-23390149
[Presentation] Is the measurement of Ca2+-release inCD19+ B cells stimulated by statin useful for prediction of muscle damage as a side effect?2012
- Author(s)
  Mori I, Hattori T, Osawa Y, Kanamori H, Kajita K, Morita H, Ishizuka T, Saito K, Ito H, Seishima M
- Organizer
  第44回日本動脈硬化学会総会・学術集会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-21390179
[Presentation] Recent advances of biomarker discovery in biological fluids by using Mass Spectrometry2012
- Author(s)
  Saito K
- Organizer
  8th International Conference of Clinical Laboratory Automation
- Place of Presentation
  Seoul, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-23390149
[Presentation] Recent advances of biomarker discovery in biological fluids by using Mass Spectrometry2012
- Author(s)
  Saito K
- Organizer
  8th International Conference of Clinical Laboratory Automation
- Place of Presentation
  Seoul, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-23650417
[Presentation] 高脂血症治療剤による培養細胞に対するCa^<2+>放出効果の基礎的検討2010
- Author(s)
  服部高幸、竹村正男、太田浩敏、大澤陽介、金森寛充、伊藤弘康、斎藤邦明、清島満
- Organizer
  第49回日本臨床検査医学会東海・北陸支部総会第320回日本臨床化学会東海北陸支部例会連合大会
- Place of Presentation
  名古屋市
- Year and Date
  2010-03-14
- Data Source
  KAKENHI-PROJECT-21390179
[Presentation] Ca2+releasing effect of stains on human CD19+primary B cells.2010
- Author(s)
  Hattori T, Saito K, Takemura M, Ito H, Ohta H, Wada H, Sei Y, Kawamura M, Seishima M
- Organizer
  第42回日本動脈硬化学会総会・学術集会
- Place of Presentation
  岐阜市
- Year and Date
  2010-06-15
- Data Source
  KAKENHI-PROJECT-21390179
[Presentation] 高脂血症治療剤による培養細胞に対するCa2+放出効果の基礎的検討2010
- Author(s)
  服部高幸、竹村正男、太田浩敏、大澤陽介、金森寛充、伊藤弘康、斎藤邦明、清島満
- Organizer
  第49回日本臨床検査医学会東海・北陸支部総会第320回日本臨床化学会東海・北陸支部例会連合大会
- Place of Presentation
  名古屋
- Year and Date
  2010-03-14
- Data Source
  KAKENHI-PROJECT-21390179

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Saito Kuniaki 齋藤 邦明

SAITOU Kuniaki 齋藤 邦明

SAITO Kuniaki 斉藤 邦明

斉藤 邦明 サイトウ クニアキ

齋藤 邦昭 サイトウ クニアキ

齋藤 邦明 サイトウ クニアキ

SAITOH Kunio 斎藤 邦明

Research Projects

Research Products

Co-Researchers

糖尿病性腎症の代謝変容の解明とその改善を基軸とした発症・進展予防Ongoing

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周産期の栄養および代謝変容が母体、胎児に及ぼす影響Principal InvestigatorOngoing

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Development of the next-generation diagnosis method for depression by using byomakers based on pathophysiological mechanismOngoing

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Analysis of carcinogenesis originated from chronic inflammation in malignant lymphomaOngoing

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Tryptophan metabolic profile is effective for preemptive medicine in depression symptomsPrincipal Investigator

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Increased serum GP88 (Progranulin) concentrations in rheumatoid arthritis.Principal Investigator

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Increases in Tryptophan-kynurenine pathway metabolism following interferon-induced depressionPrincipal Investigator

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Studies on thescale for stress induced emotional changesPrincipal Investigator

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Saito Kuniaki 齋藤邦明

SAITOU Kuniaki 齋藤邦明

SAITO Kuniaki 斉藤邦明

斉藤邦明サイトウクニアキ

齋藤邦昭サイトウクニアキ

齋藤邦明サイトウクニアキ

SAITOH Kunio 斎藤邦明