Saito Kuniaki 齋藤邦明

… Alternative Names

Researcher Number	80262765
Other IDs
External Links
Affiliation (Current)	2021: 藤田医科大学, 保健学研究科, 教授
Affiliation (based on the past Project Information) *help	2018 – 2021: 藤田医科大学, 保健学研究科, 教授 2018: 藤田医科大学, 大学院・医療科学部, 教授 2016 – 2017: 藤田保健衛生大学, 医療科学部, 教授 2015 – 2017: 藤田保健衛生大学, 保健学研究科, 教授 2016: 藤田保健衛生大学, 大学院・医療科学部, 教授 … More
Review Section/Research Field	Principal Investigator Laboratory medicine / Neurochemistry/Neuropharmacology / Laboratory medicine / Applied health science / Applied health science / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields Except Principal Investigator Laboratory medicine / Laboratory medicine / Orthopaedic surgery / Circulatory organs internal medicine … More
Keywords	Principal Investigator サイトカイン / 脳神経疾患 / AIDS / TNF-α / 炎症 / 痴呆 / 抑うつ / ストレス / バイオマーカー / アポリポタンパク … More Except Principal Investigator Atherosclerosis / ノックアウトマウス / トリプトファン代謝 / サイトカイン / TNF-α / Cytokine / バイオマーカー / 遺伝子解析 / IDO / 腫瘍 / 慢性関節リウマチ / 高脂血症 / encephalomyocarditis virus / interferon-γ / tumor necrosis factor-α / interleukin-1 / knockout mice / Apoptosis / 動脈硬化 / マクロファージ / ICAM-1 / VCAM-1 / MCP-1 / Macrophage / Bone marrow transplantation / Knockout mouse / プロテオミクス / IDO2 / メタボロミクス / 骨髄移植 / 急性肝障害モデル / TNF / IL-6 / ガラクトースアミン / LPS / 生存率 / 色彩映像 / ストレス緩和 / ストレスホルモン / POMS / STAI / がん患者のストレス / クロモグラニン / IgA / スタチン製剤 / 筋障害 / 細胞内カルシウム / リアノジン受容体 / フローサイトメトリー / FACS / CPTII遺伝子 / 脳血管障害学 / ＩＤＯ / 頸動脈プラーク / 頸動脈内膜剥離術 / ＭＲＩ / MRI / インドールアミン酸素添加酵素 / α-ガラクトシルセラミド / NKT細胞免疫療法 / α- ガラクトシルセラミド / Lp(a)リポ蛋白 / アポ(a) / 構造変異性 / 表現型 / 遺伝型 / allele number / フェノタイプ / ジェノタイプ / アポ(a)遺伝子型 / アポ(a)表現型 / 制限酵素Kpn I / 制限酵素Swa I / Lp(a) lipoprotein / Apolipoprotein(a) / structural heterogeneity / Phenotype / Genotype / Allele number / リポ蛋白(a) / 急性相反応 / 免疫組織化学 / 組織修復 / 血管内皮細胞 / 遊走 / 増殖 / 血管新生 / 遊走及び増殖 / アポ(a)イソ型 / Lipoprotein (a), Lp (a) / Acute phase reactant / Immunohistochemistry / Tissue repair / Endothelial cell / Migration / Proliferation / Angiogenesis / レトロウィルス / インターロイキン2 / 可溶性L-selectin / 接着分子 / レトロウイルス / rheumatoid arthritis / soluble interleukin-2 receptor / lymphocyte phenotypes / retrovirus / immunotherapy / アポA-IV / 遺伝子多型性 / Apo A-IV / Polymorphism / Hyperlipidemia / ウイルス心筋炎 / ウィルス心筋炎 / interleukin-6 / IFN-γ / INF-α / IL-1β / viral myocarditis / cytokine / アポトーシス / Fas蛋白 / 慢性関節リウマチ(RA) / Rheumatoid arthritis / Soluble Fas / Lipid-free apolipoprotein / Coronary heart desease / pre β HDL / Coronary heart disease / ELISA / preβ HDL / Lipid-free-free apolipoprotein / Corobary heart disease / pre βHDL / アポリポ蛋白E / Apolipoprotein E / Knockout Mice / Cytokines / 再灌流傷害 / トランスジェニックマウス / NF-κB / 炎症細胞浸潤 / 接着因子 / ケモカイン / 心筋虚血 / 再灌流障害 / 好中球 / ischemia / reperfusion injury / transgenic mice / NE-κB / inflammatory cell infiltration / cell adhesion molecules / chemokines / proteomics / macrophage / Proteomics / 臨床プロテオーム / 臨床検査 / 質量分析 / プロテオーム / clinical proteome / biomarker / clinical test / スタチン系薬剤 / 横紋筋融解症 / hyperlipidemia / statin drugs / rhabdomvosis / 腫瘍免疫 / 細胞増殖 / 自閉症スペクトラム障害 / レベチラセタム / SV2A / 自閉症 / 悪性リンパ腫 / GP88 / progranulin / 悪性リンパ;腫 / ＴＮＦ / GP８８ / 慢性炎症 / 精神薬理学 / 診断バイオマーカー / うつ病 / セロトニントランスポーター / ユビキチン化 / MAGE-D1 / 慢性腎臓病 / リン酸化 / 多発性嚢胞腎 / 多発性嚢胞腎症 / メタボローム / 環境因子 / 塩分摂取 / オミックス解析 / りん酸化タンパク質 / 網羅的解析 / 炎症 / 免疫調節因子 / インドールアミン酸素添加酵素2 / 免疫機能 / 糖尿病性腎臓病 / メタボローム解析 / NMDA受容体 / NMDA受容体拮抗薬 / 糖尿病性腎症 / トリプトファン / キヌレニン / 疾患モデル / 特発性間質性肺炎 / 人工知能 / 敵対的生成ネットワーク / CT画像 / 病理画像 / 特発生間質性肺炎 / 深層学習 Less

Development of a new diagnostic technique for idiopathic interstitial pneumonia based on a synthesis of patient images
- Principal Investigator
  
  寺本篤司
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Fujita Health University
糖尿病性腎症の代謝変容の解明とその改善を基軸とした発症・進展予防
- Principal Investigator
  
  湯澤由紀夫
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Fujita Health University
Relationship between changes in amino acid metabolism during pregnancy and postpartum depression.Principal Investigator
- Principal Investigator
  
  Saito Kuniaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Fujita Health University
Analysis of carcinogenesis originated from chronic inflammation in malignant lymphoma
- Principal Investigator
  
  Tsurumi Hisashi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Gifu University
Development of the next-generation diagnosis method for depression by using byomakers based on pathophysiological mechanism
- Principal Investigator
  
  鍋島俊隆
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Fujita Health University
Lipopolysaccharide shock reveals the immune function of indoleamine 2,3-dioxygenase 2 through regulation of IL-6/stat3 signalling
- Principal Investigator
  
  Yamamoto Yasuko
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Laboratory medicine
- Research Institution
  Fujita Health University
Tryptophan metabolic profile is effective for preemptive medicine in depression symptomsPrincipal Investigator
- Principal Investigator
  
  Saito Kuniaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  Fujita Health University
Omics analysis applicable to preemptive medicine of chronic kidney disease -focusing on comprehensive analysis of phosphorylated proteins-
- Principal Investigator
  
  Nagao Shizuko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Fujita Health University
Increased serum GP88 (Progranulin) concentrations in rheumatoid arthritis.Principal Investigator
- Principal Investigator
  
  SAITO Kuniaki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Fujita Health University
  Kyoto University
Antitumor efficacies of indoleamine 2,3-dioxygenase 2 in lewis lung carcinoma mice model.
- Principal Investigator
  
  Yamamoto Yasuko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Fujita Health University
  Kyoto University
The role of synaptic vesicle protein 2A (SV2A) in the pathophysiology and treatment of Autism spectrum disorders
- Principal Investigator
  
  MORIYA Yuka
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Meijo University
The investigation of immune regulation by IDO in NKT cell-mediated immunotherapy
- Principal Investigator
  
  HOSHI Masato
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Laboratory medicine
- Research Institution
  Suzuka University of Medical Science
Increases in Tryptophan-kynurenine pathway metabolism following interferon-induced depressionPrincipal Investigator
- Principal Investigator
  
  SAITO KUNIAKI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kyoto University
Studies on thescale for stress induced emotional changesPrincipal Investigator
- Principal Investigator
  
  SAITO Kuniaki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied health science
- Research Institution
  Kyoto University
Role of indoleamine-2,3-dioxygenase in atherosclerotic carotid artery stenosis
- Principal Investigator
  
  SUYAMA Kazuhiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagasaki University
Screening and gene analysis for the protection from muscle damage by statin drugs
- Principal Investigator
  
  SEISHIMA Mitsuru
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
The pathophysiologic role of indoleamine 2, 3-dioxygenase in viral infectious diseasesPrincipal Investigator
- Principal Investigator
  
  SAITOU Kuniaki
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kyoto University
Development of device using color images to reduce stress in cancer and/or other chronic disease patients.
- Principal Investigator
  
  SAITO Yumi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Fundamental nursing
- Research Institution
  Kyoto University
Study on the mechanism of rhabdomyosis induced by statins and gene analysis of patients with rhalxiomyasis
- Principal Investigator
  
  TAKEMURA Masao, 和田久泰
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
Study on analytical system for the etiology of autoimmune disease using two-dimensional nano LC/MS
- Principal Investigator
  
  SEISHIMA Mitsuru
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
マウス骨髄移植技術を用いた肝不全発症機構の解明とその臨床応用に関する研究
- Principal Investigator
  
  YAMADA Yasuhiro
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Gifu University
The role of proinflammatory cytokines in the generation of myocardial ischemia/reperfusion injury
- Principal Investigator
  
  WADA Hisayasu
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Gifu University
Proteome analysis of human macrophage cells associated with atherosclerosis
- Principal Investigator
  
  FUJII Hidehiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
Study on the mechanism of atherosclerotic lesion formation using cytokine-knockout mouse
- Principal Investigator
  
  SEISHIMA Mitsuru
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
A mechanism of HIV-related dementia complex - relation between TNF-α and dementia -Principal Investigator
- Principal Investigator
  
  SAITO Kuniaki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Gifu University
The method for determination of serum lipid-free apolipoprotein concentration and its clinical application
- Principal Investigator
  
  SEISHIMA Mitsuru
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
A study of the role of cytokines in the development of atherosclerosis using double knockout mice
- Principal Investigator
  
  WADA Hisayasu, 藤井秀比古
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Gifu University
TNF-αノックアウトマウスを用いたエイズ痴呆コンプレックス発症機構に関する研究Principal Investigator
- Principal Investigator
  
  斉藤邦明
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Gifu University
The role of proinflammatory cytokines in the development and progression of viral myocarditis
- Principal Investigator
  
  WADA Hisayasu
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Gifu University
Significance of soluble Fas and its related cytokines in serum of rheumatoid arthritis patients.
- Principal Investigator
  
  TAKEUCHI Shoji
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Gifu University
脳神経系疾患における組織修復と各種アポタンパク合成との関係Principal Investigator
- Principal Investigator
  
  斉藤邦明
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
Study on the role of Lp (a) as an acute phase reactant and on the effects on arterial endothelial and smooth muscle cells.
- Principal Investigator
  
  NOMA Akio
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
Basic studies of immunotherapy in relation to the serum soluble interleukin-2 receptor determination in patients with rheumatoid arthritis
- Principal Investigator
  
  TAKEUCHI Shoji
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Gifu University
Study on apo A-IV polymorphism in patients with hyperlipidemia.
- Principal Investigator
  
  SEISHIMA Mitsuru
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University
Study on structural heterogeneity of Lp(a) and its clinical significance.
- Principal Investigator
  
  MAKINO Kazuhiko
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gifu University

[Book] :Tumor Necrosis factor2014
- Author(s)
  Murakami Y, Imamura Y, Mitani S, Hoshi M, Arioka Y, Yamamoto Y, Seiyama A, Saito K.
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-23390149
[Book] Tumor Necrosis factor
- Author(s)
  Murakami Y, Imamura Y, Mitani S, Hoshi M, Arioka Y, Yamamoto Y, Seiyama A, Saito K
- Publisher
  Nova Science Publishers, Inc
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] Kynurenine 3-monooxygenase deficiency induces depression-like behavior via enhanced antagonism of α7 nicotinic acetylcholine receptors by kynurenic acid2021
- Author(s)
  Mori Yuko、Mouri Akihiro、Kunisawa Kazuo、Hirakawa Mami、Kubota Hisayoshi、Kosuge Aika、Niijima Moe、Hasegawa Masaya、Kurahashi Hitomi、Murakami Reiko、Hoshi Masato、Nakano Takashi、Fujigaki Suwako、Fujigaki Hidetsugu、Yamamoto Yasuko、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Behav Brain Res .
  
  Volume: 405 Pages: 113191-113191
- DOI
  10.1016/j.bbr.2021.113191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-20K07432, KAKENHI-PROJECT-20K07931, KAKENHI-PROJECT-18K19761
[Journal Article] Progranulin depletion inhibits proliferation via the transforming growth factor beta/SMAD family member 2 signaling axis in Kasumi-1 cells2021
- Author(s)
  Yabe Kuniaki、Yamamoto Yasuko、Takemura Masao、Hara Takeshi、Tsurumi Hisashi、Serrero Ginette、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Heliyon
  
  Volume: 7
- DOI
  10.1016/j.heliyon.2020.e05849
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-18K19761
[Journal Article] Serum Metabolic Profiles of the Tryptophan-Kynurenine Pathway in the high risk subjects of major depressive disorder2021
- Author(s)
  Sakurai Masashi、Yamamoto Yasuko、Kanayama Noriyo、Hasegawa Masaya、Mouri Akihiro、Takemura Masao、Matsunami Hidetoshi、Miyauchi Tomoya、Tokura Tatsuya、Kimura Hiroyuki、Ito Mikiko、Umemura Eri、(Boku) Aiji Sato、Nagashima Wataru、Tonoike Takashi、Kurita Kenichi、Ozaki Norio、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Pages: 1961-1961
- DOI
  10.1038/s41598-020-58806-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17108, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K10325, KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-18K19761
[Journal Article] Indoleamine-2,3-dioxygenase-1 is a molecular target for the protective activity of mood stabilizers against mania-like behavior induced by d-amphetamine2020
- Author(s)
  Tran Hai-Quyen、Shin Eun-Joo、Saito Kuniaki、Tran The-Vinh、Phan Dieu-Hien、Sharma Naveen、Kim Dae-Won、Choi Soo Young、Jeong Ji Hoon、Jang Choon-Gon、Cheong Jae Hoon、Nabeshima Toshitaka、Kim Hyoung-Chun
- Journal Title
  
  Food and Chemical Toxicology
  
  Volume: 136 Pages: 110986-110986
- DOI
  10.1016/j.fct.2019.110986
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252
[Journal Article] Lithium attenuates d‐amphetamine‐induced hyperlocomotor activity in mice via inhibition of interaction between cyclooxygenase‐2 and indoleamine‐2,3‐dioxygenase2020
- Author(s)
  Phan Dieu‐Hien、Shin Eun‐Joo、Jeong Ji Hoon、Tran Hai‐Quyen、Sharma Naveen、Nguyen Bao Trong、Jung Tae Woo、Nah Seung‐Yeol、Saito Kuniaki、Nabeshima Toshitaka、Kim Hyoung‐Chun
- Journal Title
  
  Clinical and Experimental Pharmacology and Physiology
  
  Volume: 47 Pages: 790-797
- DOI
  10.1111/1440-1681.13243
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252
[Journal Article] Kynurenine plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice2020
- Author(s)
  Tashita C, Hoshi M, Hirata A, Nakamoto K, Ando T, Hattori T, Yamamoto Y, Tezuka H, Tomita H, Hara A, Saito K.
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 26 Pages: 918-932
- DOI
  10.3748/wjg.v26.i9.918
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-19K07614, KAKENHI-PROJECT-19K08667, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-19K23873
[Journal Article] Altered kynurenine pathway metabolites in a mouse model of human attention-deficit hyperactivity/autism spectrum disorders: A potential new biological diagnostic marker2020
- Author(s)
  Murakami Y, Imamura Y, Saito K, Sakai D
- Journal Title
  
  scientific reports
  
  Volume: 10(1) Pages: 13182-13182
- DOI
  10.1038/s41598-020-60585-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08948, KAKENHI-PROJECT-19K06680, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-20K21587, KAKENHI-PROJECT-17H04364
[Journal Article] Kynurenine produced by indoleamine 2,3-dioxygenase 2 exacerbates acute liver injury by carbon tetrachloride in mice2020
- Author(s)
  Hoshi M, Osawa Y, Nakamoto K, Morita N, Yamamoto Y, Ando T, Tashita C, Nabeshima T, Saito K.
- Journal Title
  
  Toxicology
  
  Volume: 438 Pages: 152458-152458
- DOI
  10.1016/j.tox.2020.152458
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-20K07432, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-19K23873
[Journal Article] Changes in tryptophan metabolism during pregnancy and postpartum periods: Potential involvement in postpartum depressive symptoms2019
- Author(s)
  Teshigawara Tomoaki、Mouri Akihiro、Kubo Hisako、Nakamura Yukako、Shiino Tomoko、Okada Takashi、Morikawa Mako、Nabeshima Toshitaka、Ozaki Norio、Yamamoto Yasuko、Saito Kuniaki
- Journal Title
  
  Journal of Affective Disorders
  
  Volume: 255 Pages: 168-176
- DOI
  10.1016/j.jad.2019.05.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17K16375, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-16K10248
[Journal Article] 5-HT1A receptor agonist 8-OH-DPAT induces serotonergic behaviors in mice via interaction between PKCδ and p47phox2019
- Author(s)
  Tran Hai-Quyen、Shin Eun-Joo、Hoai Nguyen Bao-Chau、Phan Dieu-Hien、Kang Min-Ji、Jang Choon-Gon、Jeong Ji Hoon、Nah Seung-Yeol、Mouri Akihiro、Saito Kuniaki、Nabeshima Toshitaka、Kim Hyoung-Chun
- Journal Title
  
  Food and Chemical Toxicology
  
  Volume: 123 Pages: 125-141
- DOI
  10.1016/j.fct.2018.10.049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-17H04252
[Journal Article] Effect of antidepressant treatment on plasma levels of neuroinflammation‐associated molecules in patients with somatic symptom disorder with predominant pain around the orofacial region2019
- Author(s)
  Tomoya Miyauchia, Tatsuya Tokuraa,*, Hiroyuki Kimuraa, Mikiko Itob, Eri Umemurab, Aiji Sato (boku)c, Wataru Nagashimad, Takashi Tonoikee, Yasuko Yamamotof, Kuniaki Saitof,g, Kenichi Kuritab, Norio Ozaki
- Journal Title
  
  Human Psychopharmacology: Clinical and Experimental
  
  Volume: 34
- DOI
  10.1002/hup.2698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10325, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-19K17108
[Journal Article] Decline of Plasma Concentrations of Interleukin-18 in Severely Malnourished Patients with Anorexia Nervosa: Exploratory Analysis2019
- Author(s)
  Tanaka S, Oya-Ito T, Murakami Y, Saito K, Furuta S, Yu Y, Imaeda M, Kunimoto S, Ozaki N.
- Journal Title
  
  Nutrients
  
  Volume: 11(3) Pages: 540-540
- DOI
  10.3390/nu11030540
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K00851, KAKENHI-PROJECT-16K08948, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-16K10211
[Journal Article] Generalized pustular psoriasis from heterozygous IL36RN mutation developed after liver surgery2019
- Author(s)
  Fukushima H, Iwata Y, Numata, Saito K, Watanabe S, Kobayashi T, Sugiura K.
- Journal Title
  
  The Journal of Dermatology
  
  Volume: -
- DOI
  10.1111/1346-8138.14828
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08281, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-15H04886
[Journal Article] Indoleamine 2,3-dioxygenase 2 depletion suppresses tumor growth in a mouse model of Lewis lung carcinoma.2019
- Author(s)
  Yamasuge Wakana、Yamamoto Yasuko、Fujigaki Hidetsugu、Hoshi Masato、Nakamoto Kentaro、Kunisawa Kazuo、Mouri Akihiro、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Cancer Sci.
  
  Volume: 110 Pages: 3061-3067
- DOI
  10.1111/cas.14179
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K01969, KAKENHI-PROJECT-17K15785
[Journal Article] Chronic unpredictable mild stress-induced behavioral changes are coupled with dopaminergic hyperfunction and serotonergic hypofunction in mouse models of depression2019
- Author(s)
  Lu Qiaohui、Mouri Akihiro、Yang Yang、Kunisawa Kazuo、Teshigawara Tomoaki、Hirakawa Mami、Mori Yuko、Yamamoto Yasuko、Libo Zou、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 372 Pages: 112053-112053
- DOI
  10.1016/j.bbr.2019.112053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252
[Journal Article] Linking phencyclidine intoxication to the tryptophan-kynurenine pathway: Therapeutic implications for schizophrenia.2019
- Author(s)
  Fujigaki Hidetsugu、Mouri Akihiro、Yamamoto Yasuko、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Neurochem Int
  
  Volume: 125 Pages: 1-6
- DOI
  10.1016/j.neuint.2019.02.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K01969
[Journal Article] Alteration of specific cytokine expression patterns in patients with breast cancer2019
- Author(s)
  Kawaguchi K, Sakurai M, Yamamoto Y, Suzuki E, Tsuda M, Kataoka TR, Hirata M, Nishie M, Nojiri T, Kumazoe M, Saito K, Toi M.
- Journal Title
  
  Sci Rep
  
  Volume: 9 Pages: 2924-2924
- DOI
  10.1038/s41598-019-39476-9
- NAID
  120006578938
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07014, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H07222
[Journal Article] Selective and competitive inhibition of kynurenine aminotransferase 2 by glycyrrhizic acid and its analogues2019
- Author(s)
  Yoshida Yukihiro、Fujigaki Hidetsugu、Kato Koichi、Yamazaki Kyoka、Fujigaki Suwako、Kunisawa Kazuo、Yamamoto Yasuko、Mouri Akihiro、Oda Akifumi、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Pages: 10243-10243
- DOI
  10.1038/s41598-019-46666-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07490, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K01969, KAKENHI-PROJECT-17K08257
[Journal Article] Fatigue-induced decline in low-frequency common input to bilateral and unilateral plantar flexors during quiet standing2018
- Author(s)
  Watanabe Tatsunori、Saito Kotaro、Ishida Kazuto、Tanabe Shigeo、Nojima Ippei
- Journal Title
  
  Neurosci Letters
  
  Volume: 686 Pages: 193-197
- DOI
  10.1016/j.neulet.2018.09.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19761, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05880, KAKENHI-PROJECT-15H03044, KAKENHI-PROJECT-17H04748, KAKENHI-PROJECT-17J00700, KAKENHI-PROJECT-15KK0117
[Journal Article] Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes2018
- Author(s)
  A Sobue, N Ito, T Nagai, W Shan, K Hada, Nakajima A, Y Murakami, A Mouri, Y Yamamoto, T Nabeshima, K Saito, K Yamada
- Journal Title
  
  Glia.
  
  Volume: 66 Pages: 1034-1052
- DOI
  10.1002/glia.23299
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08948, KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-16K15201, KAKENHI-PROJECT-16K21080, KAKENHI-PROJECT-17H02220, KAKENHI-PROJECT-17H04031, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17K19483, KAKENHI-PROJECT-15H03086
[Journal Article] Sake lees extract improves hepatic lipid accumulation in high fat diet-fed mice.2018
- Author(s)
  Kubo H, Hoshi M, Matsumoto T, Irie M, Oura S, Tsutsumi H, Hata Y, Yamamoto Y, Saito K
- Journal Title
  
  Lipids Health Dis.
  
  Volume: 16(1) Pages: 106-106
- DOI
  10.1186/s12944-017-0501-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-15H03086
[Journal Article] Recurrent cutaneous Rosai-Dorfman disease.2018
- Author(s)
  Yoshimoto N, Iwata Y, Numata S, Saito K, Iwata T, Arima M, Shima H, Tahara S, Kuroda M, Sugiura K.
- Journal Title
  
  Eur J Dermatol
  
  Volume: 28 Pages: 562-563
- DOI
  10.1684/ejd.2018.3348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08281, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-15H04886
[Journal Article] Higher levels of progranulin in cerebrospinal fluid of patients with lymphoma and carcinoma with CNS metastasis.2018
- Author(s)
  Kimura Akio、Takemura Masao、Serrero Ginette、Yoshikura Nobuaki、Hayashi Yuichi、Saito Kuniaki、Inuzuka Takashi
- Journal Title
  
  J Neurooncol.
  
  Volume: 137 Pages: 455-462
- DOI
  10.1007/s11060-017-2742-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15445, KAKENHI-PROJECT-15H03086
[Journal Article] Excess maternal fructose consumption impairs hippocampal function in offspring via epigenetic modification of BDNF promoter2018
- Author(s)
  Yamazaki M, Yamada H, Munetsuna E, Ishikawa H, Mizuno G, Mukuda T, Mouri A, Nabeshima T, Saito K, Suzuki K, Hashimoto S, Ohashi K.
- Journal Title
  
  FASEB J
  
  Volume: 32 Pages: 2549-2562
- DOI
  10.1096/fj.201700783rr
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-18K17987, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17J10969, KAKENHI-PROJECT-15H03086
[Journal Article] PKCδ Knockout Mice Are Protected from Dextromethorphan-Induced Serotonergic Behaviors in Mice: Involvements of Downregulation of 5-HT1A Receptor and Upregulation of Nrf2-Dependent GSH Synthesis2018
- Author(s)
  Tran HQ, Lee Y, Shin EJ, Jang CG, Jeong JH, Mouri A, Saito K, Nabeshima T, Kim HC.
- Journal Title
  
  Molecular Neurobiology
  
  Volume: 印刷中 Pages: 7802-7821
- DOI
  10.1007/s12035-018-0938-7
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-17H04252
[Journal Article] IL-6 knockout mice are protected from cocaine-induced kindling behaviors; possible involvement of JAK2/STAT3 and PACAP signalings2018
- Author(s)
  Mai Huynh Nhu、Chung Yoon Hee、Shin Eun-Joo、Sharma Naveen、Jeong Ji Hoon、Jang Choon-Gon、Saito Kuniaki、Nabeshima Toshitaka、Reglodi Dora、Kim Hyoung-Chun
- Journal Title
  
  Food and Chemical Toxicology
  
  Volume: 116 Pages: 249-263
- DOI
  10.1016/j.fct.2018.04.031
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Journal Article] Lipopolysaccharide shock reveals the immune function of indoleamine 2,3-dioxygenase 2 through the regulation of IL-6/stat3 signalling.2018
- Author(s)
  Yamamoto Yasuko、Yamasuge Wakana、Imai Shinjiro、Kunisawa Kazuo、Hoshi Masato、Fujigaki Hidetsugu、Mouri Akihiro、Nabeshima Toshitaka、Saito Kuniaki
- Journal Title
  
  Sci Rep
  
  Volume: 8 Pages: 15917-15917
- DOI
  10.1038/s41598-018-34166-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01969, KAKENHI-PROJECT-18K19761, KAKENHI-PROJECT-17K15785, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-18K15377
[Journal Article] Association between naturally occurring anti-amyloid β autoantibodies and medial temporal lobe atrophy in Alzheimer's disease.2017
- Author(s)
  .Kimura A, Takemura M, Saito K, Yoshikura N, Hayashi Y, Inuzuka T.
- Journal Title
  
  J Neurol Neurosurg Psychiatry
  
  Volume: 88 Pages: 126-131
- DOI
  10.1136/jnnp-2016-313476
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-26461290, KAKENHI-PROJECT-26860664, KAKENHI-PROJECT-15K09337, KAKENHI-PROJECT-26460861
[Journal Article] Effect of water-immersion restraint stress on tryptophan catabolism through the kynurenine pathway in rat tissues2017
- Author(s)
  Ohta Y , Kubo H , Yashiro K , Ohashi K , Tsuzuki Y , Wada N , Yamamoto Y , Saito, K
- Journal Title
  
  JOURNAL OF PHYSIOLOGICAL SCIENCES
  
  Volume: 67 Pages: 361-372
- NAID
  40021176369
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03086
[Journal Article] Absence of kynurenine 3-monooxygenase reduces mortality of acute viral myocarditis2017
- Author(s)
  Kubo H, Hoshi M, Mouri A, Tashita C, Yamamoto Y, Nabeshima T, Saito K.
- Journal Title
  
  Immunol Lett.
  
  Volume: 181 Pages: 94-100
- DOI
  10.1016/j.imlet.2016.11.012
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-26460675, KAKENHI-PROJECT-26860376, KAKENHI-PROJECT-16K10195
[Journal Article] Association between increased serum GP88 (progranulin) concentrations and prognosis in patients with malignant lymphomas.2017
- Author(s)
  Yamamoto Y, Goto N, Takemura M, Yamasuge W, Yabe K, Takami T, Miyazaki T, Takeuchi T, Shiraki M, Shimizu M, Adachi S, Saito K, Shibata Y, Nakamura N, Hara T, Serrero G, Saito K, Tsurumi H.
- Journal Title
  
  Clin Chim Acta.
  
  Volume: 473 Pages: 139-146
- DOI
  10.1016/j.cca.2017.07.024
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09920, KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-15H03086
[Journal Article] ncreased cerebrospinal fluid progranulin correlates with interleukin-6 in the acute phase of neuromyelitis optica spectrum disorder.2017
- Author(s)
  Kimura A, Takemura M, Saito K, Serrero G, Yoshikura N, Hayashi Y, Inuzuka T.
- Journal Title
  
  J Neuroimmunol.
  
  Volume: 305 Pages: 175-181
- DOI
  10.1016/j.jneuroim.2017.01.006
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-26461290, KAKENHI-PROJECT-26860664, KAKENHI-PROJECT-15K09337, KAKENHI-PROJECT-26460861
[Journal Article] Kynurenine 3-monooxygenase is implicated inantidepressants-responsive depressive-like behaviors andmonoaminergic dysfunctions2017
- Author(s)
  Tashiro T , Murakami Y , Mouri A , Imamura Y, Nabeshima T, Yamamoto, Y , Saito, K
- Journal Title
  
  Behavioral Brain Research
  
  Volume: 317 Pages: 279-285
- DOI
  10.1016/j.bbr.2016.09.050
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-24592734, KAKENHI-PROJECT-26460240, KAKENHI-PROJECT-26460675, KAKENHI-PROJECT-26860368, KAKENHI-PROJECT-16K08948, KAKENHI-PROJECT-16K10195, KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-17H04364
[Journal Article] Serum concentrations of l-kynurenine predict clinical outcomes of patients with peripheral T-cell lymphoma, not otherwise specified2017
- Author(s)
  Shibata Y, Hara T, Matsumoto T, Nakamura N, Nakamura H, Ninomiya S, Kitagawa J, Goto N, Nannya Y, Ito H, Kito Y, Miyazaki T, Takeuchi T, Saito K, Seishima M, Takami T, Moriwaki H, Shimizu M, Tsurumi H.
- Journal Title
  
  Hematol Oncol.
  
  Volume: - Pages: 637-644
- DOI
  10.1002/hon.2318
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H06247, KAKENHI-PROJECT-16K19310, KAKENHI-PROJECT-15H03086
[Journal Article] Effect of water-immersion restraint stress on tryptophan catabolism through the kynurenine pathway in rat tissues2017
- Author(s)
  Ohta, Y ; Kubo, H ; Yashiro, K ; Ohashi, K ; Tsuzuki, Y ; Wada, N ; Yamamoto, Y ; Saito, K
- Journal Title
  
  JOURNAL OF PHYSIOLOGICAL SCIENCES 4.巻 67 5.発行年 2017
  
  Volume: 4 Pages: 361-372
- NAID
  40021176369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460675
[Journal Article] Effect of water-immersion restraint stress on tryptophan catabolism through the kynurenine pathway in rat tissues.2017
- Author(s)
  Ohta Y, Kubo H, Yashiro K, Ohashi K, Tsuzuki Y, Wada N, Yamamoto Y, Saito K.
- Journal Title
  
  J Physiol Sci.
  
  Volume: 67(3) Pages: 361-372
- DOI
  10.1007/s12576-016-0467-y
- NAID
  40021176369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H07222, KAKENHI-PROJECT-15H03086
[Journal Article] Depressive symptoms as a side effect of Interferon-α therapy induced by induction of indoleamine 2,3-dioxygenase 12016
- Author(s)
  Murakami Y, Ishibashi T, Tomita E, Imamura Y, Tashiro T, Watcharanurak K, Nishikawa M, Takahashi Y, Takakura Y, Mitani S, Fujigaki H, Ohta Y, Kubo H, Mamiya T, Nabeshima T, Kim HC, Yamamoto Y, Saito K.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Pages: 1-12
- DOI
  10.1038/srep29920
- NAID
  120006323748
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-15H04100, KAKENHI-PROJECT-24592734, KAKENHI-PROJECT-26460240, KAKENHI-PROJECT-26460675, KAKENHI-PROJECT-26860368, KAKENHI-PROJECT-16K08948
[Journal Article] L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences2016
- Author(s)
  Fujigaki H, Yamamoto Y, Saito K
- Journal Title
  
  NEUROPHARMACOLOGY
  
  Volume: 印刷中 Pages: 264-274
- DOI
  10.1016/j.neuropharm.2016.01.011
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860379, KAKENHI-PROJECT-15H03086, KAKENHI-PROJECT-26460675
[Journal Article] Prognostic value of the combination of serum l-kynurenine level and indoleamine 2,3-dioxygenase mRNA expression in acute myeloid leukemia.2016
- Author(s)
  Hara T, Matsumoto T, Shibata Y, Nakamura N, Nakamura H, Ninomiya S, Kitagawa J, Nannya Y, Shimizu M, Ito H, Saito K, Tsurumi H.
- Journal Title
  
  Leuk Lymphoma.
  
  Volume: 13 Pages: 1-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03086
[Journal Article] L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences. Neuropharmacology.2016
- Author(s)
  Fujigaki H, Yamamoto Y, Saito K.
- Journal Title
  
  j.neuropharm.
  
  Volume: S0028-3908(16) Pages: 30011-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03086
[Journal Article] Effects of various phytochemicals on indoleamine 2,3-dioxygenase 1 activity: galanal is a novel, competitive inhibitor of the enzyme.2014
- Author(s)
  Yamamoto R, Yamamoto Y, Imai S, Fukutomi R, Ozawa Y, Abe M, Matuo Y, Saito K
- Journal Title
  
  PLoS One
  
  Volume: 12;9(2)
- DOI
  10.1371/journal.pone.0088789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] Indoleamine 2,3-dioxygenase 1 is upregulated in activated microglia in mice cerebellum during acute viral encephalitis.2014
- Author(s)
  Taguchi A, Niwa M, Hoshi M, Saito K, Masutani T, Hisamatsu K, Kobayashi K, Hatano Y, Tomita H, Hara A
- Journal Title
  
  Neurosci Lett.
  
  Volume: 3564 Pages: 120-5
- DOI
  10.1016/j.neulet.2014.01.051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890270, KAKENHI-PROJECT-26860376
[Journal Article] Induction of HBsAg-specific cytotoxic T lymphocytes can be up-regulated by the inhibition of indoleamine 2, 3-dioxygenase activity2014
- Author(s)
  Ito H, Ando T, Ando K, Ishikawa T, Saito K, Moriwaki H, Seishima M
- Journal Title
  
  Immunology
- DOI
  10.1111/imm.12274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24659361
[Journal Article] Kynurenine production mediated by indoleamine 2,3-dioxygenase aggravates liver injury in HBV-specific CTL-induced fulminant hepatitis2014
- Author(s)
  Ohtaki H, Ito H, Ando K, Ishikawa T, Hoshi M, Ando T, Takamatsu M, Hara A, Moriwaki H, Saito K, Seishima M
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: S0925-4439(14) Pages: 102-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890270
[Journal Article] Indoleamine 2,3-dioxygenase 1 is upregulated in activated microglia in mice cerebellum during acute viral encephalitis.2014
- Author(s)
  Taguchi A, Niwa M, Hoshi M, Saito K, Masutani T, Hisamatsu K, Kobayashi K, Hatano Y, Tomita H, Hara A.
- Journal Title
  
  Neurosci Lett
  
  Volume: 564 Pages: 120-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890270
[Journal Article] Kynurenine production mediated by indoleamine 2,3-dioxygenase aggravates liver injury in HBV-specific CTL-induced fulminant hepatitis2014
- Author(s)
  Ohtaki H, Ito H, Ando K, Ishikawa T, Hoshi M, Ando T, Takamatsu M, Hara A, Moriwaki H, Saito K, Seishima M
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1842(9) Pages: 1464-71
- DOI
  10.1016/j.bbadis.2014.04.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24659361, KAKENHI-PROJECT-26860376
[Journal Article] Effects of indoleamine 2,3-dioxygenase deficiency on high-fat diet-induced hepatic inflammation.2013
- Author(s)
  Nagano J, Shimizu M, Hara T, Shirakami Y, Kochi T, Nakamura N, Ohtaki H, Ito H, Tanaka T, Tsurumi H, Saito K, Seishima M, Moriwaki H
- Journal Title
  
  PLoS One
  
  Volume: 9;8(9)
- DOI
  10.1371/journal.pone.0073404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-25460987, KAKENHI-PROJECT-25460988
[Journal Article] [Indoleamine 2,3-dioxygenase 1 modulates the immuneresponse; the new therapeutic targets of this drug].2013
- Author(s)
  Yamamoto Y, Murakami Y, Hoshi M, Saito K.
- Journal Title
  
  Nihon Yakurigaku Zasshi
  
  Volume: 142(2) Pages: 85-8
- NAID
  10031190742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890270
[Journal Article] Remarkable role of indoleamine 2,3-dioxygenase and tryptophan metabolites in infectious diseases: potential role in macrophage-mediated inflammatory diseases.2013
- Author(s)
  Murakami Y, Hoshi M, Imamura Y, Arioka Y, Yamamoto Y, Saito K
- Journal Title
  
  Mediators of Inflammation
  
  Volume: 2013 Pages: 391984-391984
- DOI
  10.1155/2013/391984
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-23790621, KAKENHI-PROJECT-24592734, KAKENHI-PROJECT-24890270
[Journal Article] Acquired resistance of leukemic cells to AraC is associated with the upregulation of aldehyde dehydrogenase 1 family member A2.2013
- Author(s)
  Kawasoe M, Yamamoto Y, Okawa K, Funato T, Takeda M, Hara T, Tsurumi H, Moriwaki H, Arioka Y, Takemura M, Matsunami H, Markey SP, Saito K.
- Journal Title
  
  Exp Hematol.
  
  Volume: 41(7) Pages: 597-603
- DOI
  10.1016/j.exphem.2013.03.004
- NAID
  120005302084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] IDO1 plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice.2013
- Author(s)
  Takamatsu M, Hirata A, Ohtaki H, Hoshi M, Hatano Y, Tomita H, Kuno T, Saito K, Hara A
- Journal Title
  
  Journal of Immunology
  
  Volume: 15;191(6) Pages: 3057-3064
- DOI
  10.4049/jimmunol.1203306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24790381, KAKENHI-PROJECT-24890270
[Journal Article] IDO1 plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice.2013
- Author(s)
  Takamatsu M, Hirata A, Ohtaki H, Hoshi M, Hatano Y, Tomita H, Kuno T, Saito K, Hara A.
- Journal Title
  
  J Immunol
  
  Volume: 191(6) Pages: 3057-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890270
[Journal Article] Species and cell types difference in tryptophan metabolism2013
- Author(s)
  Murakami Y, Saito K
- Journal Title
  
  Int J Tryptophan Res
  
  Volume: 21;6 Pages: 47-54
- DOI
  10.4137/ijtr.s11558
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] Pre-administration of L-tryptophan improved ADR-induced early renal failure in mice.2012
- Author(s)
  Arioka Y
- Journal Title
  
  Life Sci.
  
  Volume: 59 Pages: 100-106
- DOI
  10.1016/j.lfs.2012.06.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390179, KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24890270
[Journal Article] Posttranslational modification of indoleamine 2, 3-dioxygenase2012
- Author(s)
  Fujigaki H, Seishima M, Saito K
- Journal Title
  
  Anal Bioanal Chem
  
  Volume: 403(7) Pages: 1777-82
- DOI
  10.1007/s00216-012-5946-2
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] -Epigallocatechin gallate inhibits the expression of indoleamine 2,3-dioxygenase in human colorectal cancer cells2012
- Author(s)
  Ogawa K, Hara T, Shimizu M, Nagano J, Ohno T, Hoshi M, Ito H, Tsurumi H, Saito K, Seishima M, Moriwaki H
- Journal Title
  
  Oncol Lett
  
  Volume: 4(3) Pages: 546-550
- URL
  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673646/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890270
[Journal Article] 遺伝子検査に有用なインターネット活用2012
- Author(s)
  齋藤邦明
- Journal Title
  
  Medical Technology
  
  Volume: 40 Pages: 1580-1580
- Data Source
  KAKENHI-PROJECT-23650417
[Journal Article] High susceptibility to lipopolysaccharide-induced lethal shock in encephalomyocarditis virus-infected mice2012
- Author(s)
  Ohtaki H
- Journal Title
  
  Sci Rep
  
  Volume: 2 Pages: 367-367
- DOI
  10.1038/srep00367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790787, KAKENHI-PROJECT-24890270
[Journal Article] 健康管理におけるオミックス解析の意義2012
- Author(s)
  村上由希、松尾雄志、齋藤邦明
- Journal Title
  
  医療と検査機器試薬
  
  Volume: 35 Pages: 331-334
- Data Source
  KAKENHI-PROJECT-23650417
[Journal Article] Epigallocatechin gallate inhibits the expression of indoleamine 2, 3-dioxygenase in human colorectal cancer cells2012
- Author(s)
  Ogawa K, Hara T, Shimizu M, Nagano J, Ohno T, Hoshi M, Ito H, Tsurumi H, Saito K, Seishima M, Moriwaki H
- Journal Title
  
  Oncol Lett
  
  Volume: 4(3) Pages: 546-550
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] Posttranslational modification of indoleamine 2,3-dioxygenase2012
- Author(s)
  Fujigaki H, Seishima M, Saito K
- Journal Title
  
  Anal Bioanal Chem
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] Suppression of azoxymethane-induced colonic preneoplastic lesions in rats by 1-methyltryptophan, an inhibitor of indoleamine 2,3-dioxygenase2012
- Author(s)
  Ogawa K, Hara T, Shimizu M, Ninomiya S, Nagano J, Sakai H, Hoshi M, Ito H, Tsurumi H, Saito K, Seishima M, Tanaka T, Moriwaki H
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Pages: 951-8
- DOI
  10.1111/j.1349-7006.2012.02237.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590838, KAKENHI-PROJECT-24890270
[Journal Article] L-tryptophan-kynurenine pathway metabolites regulate type I IFNs of acute viral myocarditis in mice2012
- Author(s)
  Hoshi M
- Journal Title
  
  J Immunol.
  
  Volume: 188 Pages: 3980-3987
- DOI
  10.4049/jimmunol.1100997
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390179, KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-23790787, KAKENHI-PROJECT-24890270
[Journal Article] L-Tryptophan-kynurenine pathway metabolites regulate type I IFNs of acute viral myocarditis in mice2012
- Author(s)
  Hoshi M, Yamamoto Y, Saito K, 他4名
- Journal Title
  
  J Immunol
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149
[Journal Article] Studies on tissue and cellular distribution of indoleamine 2,3-dioxygenase 2: the absence of IDO1 upregulates IDO2 expression in the epididymis.2012
- Author(s)
  Fukunaga M, Yamamoto Y, Kawasoe M, Arioka Y, Murakami Y, Hoshi M, Saito K
- Journal Title
  
  J Histochem Cytochem.
  
  Volume: 60(11) Pages: 854-60
- DOI
  10.1369/0022155412458926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24890270
[Journal Article] Inhibition of increased indoleamine 2,3-dioxygenase activity attenuates Toxoplasma gondii replication in the lung during acute infection.2012
- Author(s)
  Murakami Y, Hoshi M, Hara A, Takemura M, Arioka Y, Yamamoto Y, Matsunami H, Funato T, Seishima M, Saito K
- Journal Title
  
  Cytokine.
  
  Volume: 59(2) Pages: 245-51
- DOI
  10.1016/j.cyto.2012.04.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390149, KAKENHI-PROJECT-24890270
[Journal Article] 遺伝子検査に有用なインターネット活用2012
- Author(s)
  斉藤邦明
- Journal Title
  
  Medical Technology
  
  Volume: 40 Pages: 1580-1580
- Data Source
  KAKENHI-PROJECT-23650417
[Journal Article] Indoleamine 2,3-dioxygenase in tumor tissue indicates prognosis in patients with diffuse large B-cell lymphoma treated with R-CHOP2011
- Author(s)
  Ninomiya S, Hara T, Saito K, 他13名
- Journal Title
  
  Ann Hematol
  
  Volume: 90(4) Pages: 409-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Indoleamine 2, 3-dioxygenase in tumor tissue indicates prognosis in patients with diffuse large B-cell lymphoma treated with R-CHOP2011
- Author(s)
  Ninomiya S, Hara T, Tsurumi H, Hoshi M, Kanemura N, Goto N, Kasahara S, Shimizu M, Ito H, Saito K, Hirose Y, Yamada T, Takahashi T, Seishima M, Takami T, Moriwaki H.
- Journal Title
  
  Ann Hematol.
  
  Volume: 90(4) Pages: 409-16
- DOI
  10.1007/s00277-010-1093-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Ability of IDO to attenuate liver injury in alpha-galactosylceramide-induced hepatitis model2011
- Author(s)
  Ito H, Hoshi M, Saito K, 他
- Journal Title
  
  J Immunol
  
  Volume: 185(8) Pages: 4554-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] L-tryptophan-mediated enhancement of susceptibility to nonalcoholic fatty liver disease is dependent on the mammalian target of rapamycin2011
- Author(s)
  Osawa Y, Kanamori H, Seki E, Hoshi M, Ohtaki H, Yasuda Y, Ito H, Suetsugu A, Nagaki M, Moriwaki H, Saito K, Seishima M
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 34800-34808
- DOI
  10.1074/jbc.m111.235473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J06850, KAKENHI-PROJECT-20390167, KAKENHI-PROJECT-21390179
[Journal Article] バイオリソース有効活用：RECHSにおける仕組みづくりの重要性2011
- Author(s)
  松尾雄志、松波英寿、竹村正男、齋藤邦明
- Journal Title
  
  臨床病理
  
  Volume: 59 Pages: 1124-1130
- Data Source
  KAKENHI-PROJECT-23650417
[Journal Article] Ability of IDO to attenuate liver in juryin alpha-galactosylceramide-in duced hepatitis model2010
- Author(s)
  Ito H, Hoshi M, Ohtaki H, Taguchi A, AndoK, Ishikawa T, Osawa Y, Hara A, Moriwaki H, Saito K, Seishima M.
- Journal Title
  
  J Immunol.
  
  Volume: 185(8) Pages: 4554-60
- DOI
  10.4049/jimmunol.0904173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Serum concentration of L-kynureninepredicts the clinical outcome of patientswith diffuse large B-cell lymphoma treated with R-CHOP2010
- Author(s)
  Yoshikawa T, Hara T, Tsurumi H, Goto N, Hoshi M, Kitagawa J, Kanemura N, Kasahara S, Ito H, Takemura M, Saito K, Seishima M, Takami T, Moriwaki H.
- Journal Title
  
  Eur J Haematol.
  
  Volume: 84(4) Pages: 304-309
- DOI
  10.1111/j.1600-0609.2009.01393.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] 映像選択システムを用いた感情・ストレスに対する色彩映像効果の解析2010
- Author(s)
  石山瑠理、齋藤ゆみ
- Journal Title
  
  健康科学(京都大学医学部保健学科紀要) 6巻
  
  Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390541
[Journal Article] The absence of IDO upregulates type I IFN production, resulting in suppression of viral replication in the retrovirus-infected mouse2010
- Author(s)
  Hoshi M, Saito K, Hara A, Taguchi A, OhtakiH, Tanaka R, Fujigaki H, Osawa Y, TakemuraM, Matsunami H, Ito H, Seishima M.
- Journal Title
  
  J Immunol.
  
  Volume: 185(6) Pages: 3305-12
- DOI
  10.4049/jimmunol.0901150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] 映像選択システムを用いた感情・ストレスに対する色彩映像効果の解析2010
- Author(s)
  石山瑠理, 齋藤ゆみ
- Journal Title
  
  健康科学 (京都大学医学部保健学科紀要) 6
  
  Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390541
[Journal Article] 好みの単色彩光による感情刺激効果2010
- Author(s)
  齋藤ゆみ、羅越、笹山哲、齋藤邦明、豊川博己
- Journal Title
  
  日本補完代替医療学会
  
  Volume: 7 Pages: 103-111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390541
[Journal Article] 好みの単色彩光による感情刺激効果2010
- Author(s)
  齋藤ゆみ、羅越、笹山哲、齋藤邦明、豊川博己
- Journal Title
  
  日本補完代替医療学会 7巻
  
  Pages: 103-111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390541
[Journal Article] The absence of IDO upregulates type I IFN production, resulting in suppression of viral replication in the retrovirus-infected mouse2010
- Author(s)
  Hoshi M, Saito K, 他10名
- Journal Title
  
  J Immunol
  
  Volume: 185(6) Pages: 3305-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Changes in serum tryptophan catabolism as an indicator of disease activity in adult T-cell leukemia/lymphoma2009
- Author(s)
  Hoshi M, Ito H, Fujigaki H, Takemura M, Takahashi T, Tomita E, Ohyama M, Tanaka R, Ohtaki H, Saito K, Seishima M.
- Journal Title
  
  LeukLymphoma.
  
  Volume: 50(8) Pages: 1372-1374
- DOI
  10.1080/10428190903045393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Marked increases in hippocampal neuron indoleamine 2, 3-dioxygenase via IFN-gamma-independent pathway following2009
- Author(s)
  Hoshi M, Saito K, Murakami, 他7名
- Journal Title
  
  Neurosci Res. 63
  
  Pages: 194-198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Statin-induced Ca2+release wasincreased in B lymphocytes in patients who showed elevated serum creatine kinase during statin treatment.2009
- Author(s)
  Hattori T, Saito K, Takemura M, Ito H, Ohta H, Wada H, Sei Y, Kawamura M,Seishima M.
- Journal Title
  
  J Atheroscler Thromb
  
  Volume: 16 Pages: 870-7
- URL
  https://www.jstage.jst.go.jp/browse/jat
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390179
[Journal Article] Marked increases in hippocampal neuron indoleamine 2, 3-dioxygenase via IFN-gamma-independent pathway following transient global ischemia in mouse2009
- Author(s)
  Hoshi M, Saito K, Murakami Y, Taguchi A, Fujigaki H, Tanaka R, Takemura M, Ito H, Hara A, Seishima M.
- Journal Title
  
  Neurosci Res.
  
  Volume: 63(3) Pages: 194-198
- DOI
  10.1016/j.neures.2008.12.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] Interaction between LPS-induced NO production and IDO activity in mouse peritoneal cells in the presence of activated Valpha14 NKT cells2009
- Author(s)
  Ohtaki H, Ito H, Ando K, Ishikawa T, HoshiM, Tanaka R, Osawa Y, Yokochi T, MoriwakiH, Saito K, Seishima M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 389(2) Pages: 229-34
- DOI
  10.1016/j.bbrc.2009.08.120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] 色彩映像の心理的効果-映像選択システムの併用による色彩映像の感情刺激効果の検討2008
- Author(s)
  齋藤ゆみ, 笹山哲
- Journal Title
  
  日本補完代替医療学会誌 5
  
  Pages: 225-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390541
[Journal Article] Localization and spatiotemporal expression of IDO following transient forebrain ischemia in gerbils.2008
- Author(s)
  Taguchi A, Hara A, Saito K, 他4名
- Journal Title
  
  Brain Res. 1217
  
  Pages: 78-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390167
[Journal Article] 色彩映像の心理的効果-映像選択システムの併用による色彩映像の感情刺激効果の検討2008
- Author(s)
  齋藤ゆみ、笹山哲、菅佐和子、池本正生
- Journal Title
  
  日本補完代替医療学会誌 5巻
  
  Pages: 225-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390541
[Journal Article] Nitration and inactivation of IDO by peroxynitrite.2006
- Author(s)
  Fujigaki H, Saito K, Lin F, Fujigaki S, Takahashi K, Martin BM, Chen CY, Masuda J, Kowalak J, Takikawa O, Seishima M, Markey SP.
- Journal Title
  
  The Journal of Immunology 176(1)
  
  Pages: 372-379
- Data Source
  KAKENHI-PROJECT-17390161
[Journal Article] The signal transducer and activator of trenscription 1α and interferon regulatory factor 1are not essential for the induction of indoleamine 2,3-dioxygenase by lipopolysaccharide : involvement of p38 mitogen-activated protein kinase and nuclear factor-κ B pathways, and synergistic effect of several proinflammatory cytokines.2006
- Author(s)
  Fujigaki H, Saito K, Fujigaki S, Takemura M, Sudo K, lshiguro H, Seishima M.
- Journal Title
  
  The Journal of Biochemistry 139(4)
  
  Pages: 655-662
- Data Source
  KAKENHI-PROJECT-18590525
[Journal Article] Nitration and inactivation of indoeamine 2,3-dioxygenase by peroxynitrite2006
- Author(s)
  Fujigaki H, Saito K, Seishima M他
- Journal Title
  
  J.Immunol 176
  
  Pages: 372-379
- Data Source
  KAKENHI-PROJECT-17390161
[Journal Article] The signal transducer and activity of transcription 1a and interferon regulatory factor 1 are not essential for the induction of indoleamine 2,3-dioxygenase by lipopolysaccharide2006
- Author(s)
  Fujigaki H, Saito K, Seishima M他
- Journal Title
  
  J.Biochem. (In Press)
- Data Source
  KAKENHI-PROJECT-17390161
[Patent] 関節リューマチ患者における生物学的製剤の有効性の予測方法2013
- Inventor(s)
  斉藤邦明, 坪井彩, 山本康子
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Number
  2013-127092
- Filing Date
  2013-06-18
- Data Source
  KAKENHI-PROJECT-23390149
[Patent] 免疫抵抗性疾患耐性をもった動物の育種方法2010
- Inventor(s)
  斉藤邦明、市村直也
- Industrial Property Rights Holder
  斉藤邦明、成宮明
- Filing Date
  2010
- Data Source
  KAKENHI-PROJECT-20390167
[Presentation] Classification and Segmentation of Idiopathic Interstitial Pneumonia Using 3D U-Net2021
- Author(s)
  Nonoko Takeuchi, Atsushi Teramoto, Kazuyoshi Imaizumi, Kuniaki Saito, Hiroshi Fujita,
- Organizer
  IFMIA 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08060
[Presentation] 3D U-Netを用いたCT画像における特発性間質性肺炎の領域抽出及び鑑別2020
- Author(s)
  竹内野々子, 寺本篤司, 今泉和良, 齋藤邦明,藤田広志
- Organizer
  医用画像情報学会令和2年度秋季(第188回)大会
- Data Source
  KAKENHI-PROJECT-20K08060
[Presentation] End-to-End Model for Analysis of Idiopathic Interstitial Pneumonia Using 3D U-Net2020
- Author(s)
  Nonoko Takeuchi, Atsushi Teramoto, Kazuyoshi Imaizumi, Kuniaki Saito, Hiroshi Fujita,
- Organizer
  第76回日本放射線技術学会総会学術大会
- Data Source
  KAKENHI-PROJECT-20K08060
[Presentation] QPRTの欠損はキノリン酸によるドパミン作動性神経系における酸化ストレスを介した運動・認知機能障害を惹起する．2020
- Author(s)
  毛利彰宏、新島萌、勅使河原知明、國澤和生、窪田悠力、山本康子、齋藤邦明、鍋島俊隆
- Organizer
  第９３回日本薬理学会年会（2020.3.16-18横浜）
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] トリプトファン代謝酵素　indoleamine 2,3-dioxygenase 2欠損が脳内に及ぼす影響2020
- Author(s)
  石川雅樹、山本康子、齋藤邦明
- Organizer
  第60回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] 疾患バイオマーカーとしてのトリプトファン ― キヌレニン経路2020
- Author(s)
  山本康子、藤垣英嗣、齋藤邦明
- Organizer
  第67回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] トリプトファン-キヌレニン代謝を基軸とした創薬・診断薬開発～皮膚科免疫関連疾患を視野に入れて～2020
- Author(s)
  齋藤邦明
- Organizer
  第71回日本皮膚科学会中部支部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] Lipopolysaccharide injection triggers Indoleamine-2,3-dioxygenase1 and miR-874-3p interaction which leads to depression-like behavior in mouse．2019
- Author(s)
  Willy Jaya Suento, Kazuo Kunisawa, Bolati Wulaer, Tsubasa Iida, Aika Kosuge, Akihiro Mouri, Kuniaki Saito, Toshitaka Nabeshima
- Organizer
  AsCNP2019 (2019.10.11-13, 福岡)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] 糖尿病性腎症における代謝変容の役割の解明2019
- Author(s)
  高橋和男、坪井直毅、長尾静子、齋藤邦明、湯澤由紀夫
- Organizer
  第49回日本腎臓学会西部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08715
[Presentation] Alteration of Tryptophan-Kynurenine Metabolites in the Serum and Kidney in Diabetic Nephropathy2019
- Author(s)
  Shoko Matsushita,Kazuo Takahashi,Ryosuke Umeda,Naotake Tsuboi,Kazuki Nakajima,1 Aya Yoshimura,1 Kanako Kumamoto,1 Masanori Kugita,1 Hidetsugu Fujigaki,1 Akihiro Mouri,1 Yasuko Yamamoto,1 Toshitaka Nabeshima,Mitsutoshi Setou,Shizuko Nagao,Kuniaki Saito,Yukio Yuzawa
- Organizer
  Kidney Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08715
[Presentation] IDO1は社会的敗北ストレス下におけるストレス脆弱性を制御する/ IDO1 regulates vulnerability to social defeat stress.2019
- Author(s)
  國澤和生、毛利彰宏、小菅愛加、飯田翼、Wulaer Bolati、山本康子、齋藤邦明、鍋島俊隆：
- Organizer
  第42回日本神経科学大会第62回日本神経化学会大会合同大会（2019.7.25-28　新潟）
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] トリプトファン-キヌレニン代謝をターゲットとした創薬・診断薬開発2019
- Author(s)
  齋藤邦明
- Organizer
  第39回日本トリプトファン研究会学術集会（2019/12/14-15千葉）
- Invited
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] The deficit of quinolinic acid phosphoribosyltransferase induces hypolocomotion and cognitive impairment through impairment of dopaminergic neuronal function2019
- Author(s)
  Moe Niijima, Akihiro Mouri, Tomoaki Teshigawara, Kazuo Kunisawa, Hisayoshi Kubota, Mami Hirakawa, Yuko Mori, Masato Hoshi, Yasuko Yamamoto, Toshitaka Nabeshima, Kuniaki Saito
- Organizer
  AsCNP2019 (2019.10.11-13, 福岡)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] IDO1 regulates vulnerability to social defeat stress2019
- Author(s)
  國澤和生、毛利彰宏、小菅愛加、飯田翼、Wulaer Bolati、山本康子、齋藤邦明、鍋島俊隆
- Organizer
  NEURO2019（2019/7/25-28新潟）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] 2型糖尿病性腎症モデルラットにおける腎組織中キノリン酸の分布解析2019
- Author(s)
  松下祥子、高橋和男、吉村文、熊本海生航、伊藤辰将、坪井直毅、毛利彰宏3、山本　康子4、藤垣　英嗣4、中嶋和紀、釘田雅則、國澤和生、鍋島俊隆、齋藤邦明、瀬藤光利、長尾静子、湯澤由紀夫
- Organizer
  第62回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08715
[Presentation] Repeated social defeat stress induces depression-like behavior through the decrease of GLT-1 ubiquitination in the prefrontal cortex of mice．2019
- Author(s)
  Aika Kosuge, Kazuo Kunisawa, Tsubasa Iida, Bolati Wulaer, Willy Jaya Suento, Yasuko Yamamoto, Akihiro Mouri, Kuniaki Saito, Toshitaka Nabeshima
- Organizer
  AsCNP2019 (2019.10.11-13, 福岡)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Repeated social defeat stress induces microglial activation and myelin abnormality in the corpus callosum: a potential link to depression-like behavior.2019
- Author(s)
  Tsubasa Iida, Kazuo Kunisawa, Sei Saitoh, Aika Kosuge, Bolati Wulaer, Willy Jaya Suento, Yasuko Yamamoto, Akihiro Mouri, Kuniaki Saito and Toshitaka Nabeshima
- Organizer
  AsCNP2019 (2019.10.11-13, 福岡)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] The Role of Tryptophan Metabolism and Inflammation in Depression: The Target for Novel Diagnosis and Therapy藤2019
- Author(s)
  齋藤邦明
- Organizer
  藤田医科大学ブランディング事業国際シンポジウム（201910/14　名古屋）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] Involvement of Noradrenergic Function in the Behavioral Changes in MAGE-D1 KO Mice2019
- Author(s)
  毛利彰宏、平川茉実、渡辺研、國澤和生、森優子、窪田悠力、新島萌、山本康子、野田幸裕、鍋島俊隆、齋藤邦明
- Organizer
  NEURO2019（2019/7/25-28新潟）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] 慢性予測不能軽度ストレス負荷は側坐核のドパミン機能亢進と前頭皮質・海馬のセロトニン機能低下を伴ううつ様行動を惹起する2019
- Author(s)
  毛利彰宏、キョヘイル、ヤンヤン、國澤和生、勅使河原知明、平川茉実、森優子、山本康子、シュウリボ、鍋島俊隆、齋藤邦明
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] 人工知能を用いたストレス負荷マウスの表情評価.2019
- Author(s)
  多田遼矢，毛利彰宏，寺本篤司，國澤和生，山田あゆみ，長谷川眞也，倉橋仁美，浅野僚子，窪田悠力，新島萌，山本康子，齋藤邦明，鍋島俊隆
- Organizer
  日本生体医工学会東海支部大会（2019.10.26名古屋）
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] The role of tryptophan metabolism in major depressive disorder2019
- Author(s)
  Kazuo Kunisawa, Akihiro Mouri, Aika Kosuge, Tsubasa Iida, Bolati Wulaer, Yasuko Yamamoto, Kuniaki Saito, Toshitaka Nabeshima
- Organizer
  AsCNP2019 (2019.10.11-13, 福岡)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Deficiency of kynurenine 3-monooxygenase increases vulnerability to the PCP-induced behavioral abnormalities2019
- Author(s)
  Hisayoshi Kubota, Akihiro Mouri, Kazuo Kunisawa, Moe Niijima, Mami Hirakawa, Yuko Mori, Yasuko Yamamoto, Toshitaka Nabeshima, Kuniaki Saito
- Organizer
  AsCNP2019 (2019.10.11-13, 福岡)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Impaired neurogenesis in the dentate gyrus of adult ShatiKO mice2019
- Author(s)
  Bolati Wulaer, Kazuo Kunisawa, Willy Jaya Suento, Tsubasa Iida, Aika Kosuge, Atsumi Nitta, Akihiro Mouri, Kuniaki Saito Toshitaka Nabeshima
- Organizer
  AsCNP2019 (2019.10.11-13, 福岡)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Antidepressant effects of XJ-Et-8 in mice chronically exposed to corticosterone2019
- Author(s)
  Jiajing Shan, Akihiro Mouri, Yang Yang, Qiaohui Lu, Kazuo Kunisawa , Tomoaki Teshigawara , Mami Hirakawa , Yuko Mori , Yasuko Yamamoto , Zou Libo , Toshitaka Nabeshima, Kuniaki Saito,
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Lipopolysaccharide injection triggers Indoleamine-2,3-dioxygenase1 and miR-874-3p interaction which leads to depression-like behavior in mouse2019
- Author(s)
  Willy Jaya Suento, Kazuo Kunisawa, Bolati Wulaer, Tsubasa Iida, Aika Kosuge, Akihiro Mouri, Kuniaki Saito, Toshitaka Nabeshima
- Organizer
  AsCNP（2019/10/11-13福岡）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] Involvement of Noradrenergic Function in the Behavioral Changes in MAGE-D1 KO Mice.2019
- Author(s)
  毛利彰宏、平川茉実、渡辺研、國澤和生、森優子、窪田悠力、新島萌、山本康子、野田幸裕、鍋島俊隆、齋藤邦明
- Organizer
  第42回日本神経科学大会第62回日本神経化学会大会合同大会（2019.7.25-28　新潟）
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] トリプトファン代謝経路が抑うつに与える影響-基礎研究と臨床研究のクロストーク-、2019
- Author(s)
  毛利彰宏、國澤和生、窪田悠力、新島萌、森優子、勅使河原知明、藤垣英嗣、山本康子、尾崎紀夫、齋藤邦明、鍋島俊隆
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2019（2019.8.31東京）
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Development of biomarker for depression focused on serotonergic systems from animal models.2019
- Author(s)
  Akihiro Mouri, Kazuo Kunisawa, Hidetsugu Fujigaki, Yasuko Yamamoto, Kuniaki Saito, Toshitaka Nabeshima
- Organizer
  AsCNP2019 (2019.10.11-13, 福岡)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] トリプトファン代謝経路が抑うつに与える影響-基礎研究と臨床研究のクロストーク-2019
- Author(s)
  毛利彰宏、國澤和生、窪田悠力、新島萌、森優子、勅使河原知明、藤垣英嗣、山本康子、尾崎紀夫、齋藤邦明、鍋島俊隆
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2019（2019/8/31東京）
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] IDO1は社会的敗北ストレス下におけるストレス脆弱性を制御する2019
- Author(s)
  國澤和生毛利彰宏小菅愛加飯田翼 Wulaer Bolati 山本康子齋藤邦明鍋島俊隆
- Organizer
  第42回日本神経科学大会第62回日本神経化学会大会合同大会（2019/7/24-27新潟）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] 感染症におけるオミックス解析の応用2019
- Author(s)
  齋藤邦明
- Organizer
  第60回日本臨床ウイルス学会（2019/5/25名古屋）
- Invited
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] Kynurenine 3-monooxygenase regulates expression of depression-like behavior via enhanced antagonism of α7 nicotinic acetylcholine receptor by kynurenic acid. AsCNP2019 (2019.10.11-13, 福岡)2019
- Author(s)
  Akihiro Mouri, Yuko Mori, Kazuo Kunisawa, Mami Hirakawa, Tomoaki Teshigawara, Hisayoshi Kubota, Moe Niijima, Hidetsugu Fujigaki, Yasuko Yamamoto, Toshitaka Nabeshima, Kuniaki Saito
- Organizer
  AsCNP2019 (2019.10.11-13, 福岡)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Involvement of kynurenine 3-monooxygenase in the vulnerability to the PCP-induced behavioral abnormalities2018
- Author(s)
  Hisayoshi Kubota, Akihiro Mouri, Kazuo Kunisawa, Moe Niijima, Tomoaki Teshigawara, Mami Hirakawa, Yuko Mori, Yasuko Yamamoto, Toshitaka Nabeshima ,Kuniaki Saito
- Organizer
  WCP2018 Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] Prostaglandin E receptor subtype EP1 deficiency elicits AD/HD-like behavior correlated with a dysfunction of dopamine D1 receptor-ERK signaling in the prefrontal cortex2018
- Author(s)
  Akihiro Mouri,Tomoyuki Furuyashiki, Kazuo Kunisawa, Yasuko Yamamoto, Kiyofumi Yamada, Yukihiro Noda, Kuniaki Saito, Shu Narumiya, Toshitaka Nabeshima
- Organizer
  WCP2018 Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] 薬学研究が支える臨床化学精神疾患モデル動物研究からのバイオマーカー研究　薬学・医学から臨床化学へのトランスレーショナル研究2018
- Author(s)
  毛利彰宏, 國澤和生, 山本康子, 齋藤邦明, 鍋島俊隆
- Organizer
  第５８回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] Lipopolysaccharide shock reveals the immune function of indoleamine 2, 3-dioxygenase 2 through regulation of IL-6/STAT3 signalling.2018
- Author(s)
  1.Yasuko Yamamoto, Wakana Yamasuge, Shinjiro Imai, Kazuo Kunisawa, Masato Hoshi, Hidetsugu Fujigaki, Akihiro Mouri, Toshitaka Nabeshima, Kuniaki Saito.
- Organizer
  15th International Society for Tryptophan Research Conference.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07222
[Presentation] Exposure to valproic acid during pregnancy induces autism endophenotypes in the male offspring2018
- Author(s)
  Mami HIrakawa, Akihiro Mouri, Kazuo Kunisawa, Yuko Mori, Moe Niijima ,Hisayoki Kubota, Tomoaki Teshigawara, Hidetsugu Fujigaki, Toshitaka Nabeshima, Kuniaki Saito
- Organizer
  WCP2018 Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] DEVELOPMENT OF ANIMAL MODELS AND BIOMARKER FOR DEPRESSION FOCUSED ON SEROTONERGIC SYSTEMS2018
- Author(s)
  Akihiro Mouri1, Kazuo Kunisawa2, Hidetsugu Fujigaki, Yasuko Yamamoto, Kuniaki Saito, Toshitaka Nabeshima
- Organizer
  15th International Society for Tryptophan Research (ISTRY) Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Development of kynurenine aminotransferase II inhibitor screening assay.2018
- Author(s)
  2.Kyoka Yamazaki, Hidetsugu Fujigaki, Yukihiro Yoshida, Yasuko Yamamoto, Toshitaka Nabeshima, Kuniaki Saito.
- Organizer
  15th International Society for Tryptophan Research Conference.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07222
[Presentation] NGSを用いた小脳変性マウスのExome解析および原因遺伝子候補の神経栄養因子との関連　脳機能改善素材開発試験の応用を目指して2018
- Author(s)
  別府秀彦, 稲垣秀人, 西井一宏, 新里昌功, 千原猛, 毛利彰宏, 齋藤邦明, 高橋久英, 倉橋浩樹
- Organizer
  第１６回日本機能性食品医用学会
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] 酵素反応を用いたキノリン酸測定法の開発2018
- Author(s)
  山崎杏佳, 藤垣英嗣, 吉田幸弘, 木村文香, 山本康子, 齋藤邦明
- Organizer
  第５８回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] Development of animal models and biomarker for depression focused on serotonergic systems2018
- Author(s)
  Akihiro Mouri, Kazuo Kunisawa, Hidetsugu Fujigaki, Yasuko Yamamoto , Kuniaki Saito, Toshitaka Nabeshima
- Organizer
  15th International Society for Tryptophan Research (ISTRY) Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] Repeated social defeat induces social interaction deficits associated with the alteration of kynurenine pathway activity in the prefrontal cortex2018
- Author(s)
  Kazuo Kunisawa, Akihiro Mouri, Aika Kosuge, Tsubasa Iida, Yasuko Yamamoto, Kuniaki Saito, Toshitaka Nabeshima
- Organizer
  WCP2018 Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] ストレス(モデル)と分子うつ病発症におけるトリプトファン代謝の関与2018
- Author(s)
  國澤和生, 毛利彰宏, 山本康子, 齋藤邦明, 鍋島俊隆
- Organizer
  第34回日本ストレス学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] 神経精神疾患の病態メカニズムに基づく新たな治療分子標的トリプトファン代謝に注目したうつ病病態解明と診断・治療薬戦略2018
- Author(s)
  毛利彰宏, 國澤和生, 山本康子, 藤垣英嗣, 齋藤邦明, 鍋島俊隆
- Organizer
  第２８回日本臨床精神神経薬理学会・第４８回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] Involvement of kynurenine pathway in behavioral impairments in the offspring induced by the prenatal poly I: C injection2018
- Author(s)
  Moe Niijima, Akihiro Mouri, Tomoaki Teshigawara, Kazuo Kunisawa, Hisayoshi Kubota, Mami Hirakawa, Yuko Mori, Masato Hoshi, Toshitaka Nabeshima, Kuniaki Saito
- Organizer
  WCP2018 Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] 10年後の臨床化学を考える診断薬開発の未来　求められる先制診断システム2018
- Author(s)
  齋藤邦明
- Organizer
  第５８回日本臨床化学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] MAGE-D1 REGULATES EXPRESSION OF DEPRESSION-LIKE BEHAVIOR THROUGH SEROTONIN TRANSPORTER UBIQUITYLATION2018
- Author(s)
  Akihiro Mouri, Kazuo Kunisawa, Mami Hirakawa, Yuko Mori, Ken Watanabe, Hidetsugu Fujigaki, Yasuko Yamamoto, Yukihiro Noda, Kuniaki Saito, Toshitaka Nabeshima
- Organizer
  15th International Society for Tryptophan Research (ISTRY) Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Kynurenine 3-monooxygenase is essential for de novo biosynthesis of NAD+.2018
- Author(s)
  3.Yukihiro Yoshida, Hidetsugu Fujigaki, Yasuko Yamamoto, Kyoka Yamazaki, Fumika Kimura, Hisako Kubo, Tsutomu Fukuwatari, Toshitaka Nabeshima, Kuniaki Saito.
- Organizer
  15th International Society for Tryptophan Research Conference.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07222
[Presentation] Prostaglandin E receptor subtype EP1 deficiency elicits AD/HD-like behavior correlated with a dysfunction of dopamine D1 receptor-ERK signaling in the prefrontal cortex2018
- Author(s)
  Akihiro Mouri, Tomoyuki Furuyashiki, Kazuo Kunisawa, Yasuko Yamamoto, Kiyofumi Yamada, Yukihiro Noda, Kuniaki Saito, Shu Narumiya, TOshitaka Nabeshima
- Organizer
  WCP2018 Kyoto
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] うつ病発症におけるトリプトファン代謝の関与2018
- Author(s)
  國澤和生、毛利彰宏、山本康子、齋藤邦明、鍋島俊隆
- Organizer
  第３４回日本ストレス学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] 糖尿病モデルマウスにおけるキヌレニン経路代謝物の腎組織イメージング質量分析2018
- Author(s)
  松下祥子, 高橋和男, 伊藤辰将, 山本康子, 藤垣英嗣, 毛利彰宏, 中嶋和紀, 尾之内高慶, 辰川英樹, 釘田雅則, 長尾静子, 人見清隆, 齋藤邦明, 瀬藤光利, 湯澤由紀夫
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19761
[Presentation] 酵素法を用いたキヌレニン定量法の開発．2017
- Author(s)
  吉田幸弘、藤垣英嗣、山本康子、齋藤邦明
- Organizer
  第57回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] Kynurenine 3-monooxygenase遺伝子R452C変異解析の基礎的検討．2017
- Author(s)
  藤垣英嗣、吉田幸弘、山本康子、齋藤邦明
- Organizer
  第57回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] Depressive symptoms and L-Tryptophan -Kynurenine pathway metabolism focus on neuro-inflammation.2017
- Author(s)
  Kuniaki Saito
- Organizer
  The 5th Congress of Asian College pof Neuropsychopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] 酵素法を用いたキヌレニン定量法の開発．2017
- Author(s)
  吉田幸弘、藤垣英嗣、山本康子、齋藤邦明
- Organizer
  第57回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H07222
[Presentation] RA患者の血中インフリキシマブ濃度測定の意義2017
- Author(s)
  竹村正男、佐藤正夫、伊藤弘養、　清島　満、齋藤邦明
- Organizer
  第64回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] 先制医療の実現のために～次世代創薬・診断薬開発～2017
- Author(s)
  齋藤邦明
- Organizer
  臨床検査薬協会・技術委員会総会
- Place of Presentation
  ヒューリックカンファレンスルーム(東京
- Invited
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] Depressive symptoms and L-Tryptophan -Kynurenine pathway metabolism focus on neuro-inflammation.2017
- Author(s)
  Kuniaki Saito
- Organizer
  The 5th Congress of Asian College pof Neuropsychopharmacology( 2017.4.27-29, Indonesia)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04252
[Presentation] Kynurenine aminotransferase 2を用いたキヌレニン測定法の開発．2017
- Author(s)
  吉田幸弘、藤垣英嗣、山﨑杏佳、山本康子、齋藤邦明
- Organizer
  第38回日本トリプトファン研究会学術集
- Data Source
  KAKENHI-PROJECT-17H07222
[Presentation] 脳神経疾患における治療標的としてのトリプトファン-キヌレニン代謝酵素2017
- Author(s)
  齋藤邦明
- Organizer
  第23回脳の医学・生物学研究会
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] Kynurenine aminotransferase 2を用いたキヌレニン測定法の開発．2017
- Author(s)
  吉田幸弘、藤垣英嗣、山﨑杏佳、山本康子、齋藤邦明
- Organizer
  第38回日本トリプトファン研究会学術集
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] Kynurenine 3-monooxygenase遺伝子R452C変異解析の基礎的検討．2017
- Author(s)
  藤垣英嗣、吉田幸弘、山本康子、齋藤邦明
- Organizer
  第57回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-17H07222
[Presentation] アストログリアにおけるMHCIの発現とその行動学的・神経病理学的影響2017
- Author(s)
  祖父江顕,伊藤教道,羽田和弘,中島晶,村上由希,毛利彰宏,山本康子,鍋島俊隆,齋藤邦明,永井拓,山田清文
- Organizer
  第39回日本生物学的精神医学会・第47回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] 周産期における抑うつにおけるユビキチン化セロトニントランスポーターの変化2016
- Author(s)
  毛利彰宏、椎野智子、勅使河原知明、山本康子、野田幸裕、尾崎紀夫、齋藤邦明、鍋島俊隆　「
- Organizer
  第56回日本臨床化学会学術大会
- Place of Presentation
  熊本県民交流館パレア(熊本）
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] 周産期における抑うつにおけるトリプトファン代謝関連分子の変化2016
- Author(s)
  勅使河原知明、久保緋紗子、毛利彰宏、鍋島俊隆、尾崎紀夫、山本康子、齋藤邦明
- Organizer
  第56回日本臨床化学会学術大会
- Place of Presentation
  熊本県民交流館パレア(熊本）
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] 周産期における抑うつにおけるトリプトファン代謝関連分子の変化2016
- Author(s)
  勅使河原知明、久保緋紗子、毛利彰宏、鍋島俊隆、尾崎紀夫、山本康子、齋藤邦明
- Organizer
  第56回日本臨床化学会学術大会
- Place of Presentation
  熊本県民交流館パレア(熊本）
- Data Source
  KAKENHI-PROJECT-26460675
[Presentation] 健常時からの暦年的バイオバンクの活用 -代謝変容に着目したバイオマーカー検索-2015
- Author(s)
  斉藤邦明
- Organizer
  第55回日本臨床化学会年次学術集会
- Place of Presentation
  大阪大学コンベンションセンター（吹田市）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] 先制医療を実現するためのバイオバンク2015
- Author(s)
  斉藤邦明
- Organizer
  第62回日本臨床検査医学会学術集会
- Place of Presentation
  長良川国際会議場（岐阜）
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] 先制医療実現のために　ー不健康を科学するー2015
- Author(s)
  斉藤邦明
- Organizer
  日本健康科学会第31回学術集会・次期学術集会長講演
- Place of Presentation
  ホテルグランドヒル市ヶ谷（東京）
- Year and Date
  2015-08-21
- Invited
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] Increased serum GP88(progranulin) concentration in rheumatoid arthritis.2015
- Author(s)
  Yamamoto　Y, Saito K
- Organizer
  IFCC Paris
- Place of Presentation
  Le Palais des Congres de paris(France)
- Year and Date
  2015-06-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670278
[Presentation] RA患者におけるバイオマーカー GP88の検討2015
- Author(s)
  竹村正男、佐藤正夫、山本康子、斎藤邦明
- Organizer
  第27回中部リウマチ学会
- Place of Presentation
  ウインクあいち（名古屋市）
- Year and Date
  2015-09-04
- Data Source
  KAKENHI-PROJECT-26670278
[Presentation] The role of L-tryptophan metabolism via indoleamine 2,3-dioxygenase on cytokine-induced depressive symptoms2015
- Author(s)
  Saito K
- Organizer
  ISTRY conference Symposium Pathology III
- Place of Presentation
  Grand Rapids（ USA）
- Year and Date
  2015-09-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03086
[Presentation] 関節リウマチ症例における血清Progranulinの測定2015
- Author(s)
  山本康子, 竹村正男, 佐藤正夫, 斉藤邦明
- Organizer
  第55回日本臨床化学会
- Place of Presentation
  大阪大学コンベンションセンター（吹田市）
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-26670278
[Presentation] Recent advances of biomarker discovery in biological fluids by using Mass Spectrometry2013
- Author(s)
  Saito,K
- Organizer
  8th International Conference of Clinical Laboratory Automation
- Place of Presentation
  Seoul, Korea(招待講演)
- Data Source
  KAKENHI-PROJECT-23650417
[Presentation] Labdane-type diterpene, constituent from myoga which are traditional Japanese food inhibit enzyme activity and gene expression of indoleamine 2,3-dioxygenase 12013
- Author(s)
  S Imai, R Yamamoto, Y Yamamoto, Y Katayanagi, R Fukutomi, M Abe, Y Ozawa, K Saito
- Organizer
  15thInternational Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-23390149
[Presentation] 免疫調節因子インドールアミン 2,3-ジオキシゲナーゼ1の新規阻害剤探索：フィトケミカルを中心として2013
- Author(s)
  山本梨絵, 山本康子, 今井伸二郎, 松尾雄志, 小澤好夫, 阿部雅子, 福富竜太, 斉藤邦明
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23390149
[Presentation] 免疫調節因子インドールアミン 2, 3-ジオキシゲナーゼ1の新規阻害剤探索 : フィトケミカルを中心として2013
- Author(s)
  山本梨絵, 山本康子, 今井伸二郎, 松尾雄志, 小澤好夫, 阿部雅子, 福富竜太, 斉藤邦明
- Organizer
  第36回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23390149
[Presentation] 疾患メタボローム・疾患プロテオミクス解析2013
- Author(s)
  斉藤邦明
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-23390149
[Presentation] Recent advances of biomarker discovery in biological fluids by using Mass Spec trometry2013
- Author(s)
  Saito, K
- Organizer
  8th International Conference of Clinica l Laboratory Automation
- Place of Presentation
  Seoul, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-23390149
[Presentation] Labdane-type diterpene, constituent from myoga which are traditional Japanese food inhibit enzyme activity and gene expression of in doleamine 2, 3-dioxygenase 12013
- Author(s)
  Imai, R Yamamoto, Y Yamamoto, Y Katayan agi, R Fukutomi, M Abe, Y Ozawa, K Saito
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-23390149
[Presentation] Is the measurement of Ca2+-release inCD19+ B cells stimulated by statin useful for prediction of muscle damage as a side effect?2012
- Author(s)
  Mori I, Hattori T, Osawa Y, Kanamori H, Kajita K, Morita H, Ishizuka T, Saito K, Ito H, Seishima M
- Organizer
  第44回日本動脈硬化学会総会・学術集会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-21390179
[Presentation] Recent advances of biomarker discovery in biological fluids by using Mass Spectrometry2012
- Author(s)
  Saito K
- Organizer
  8th International Conference of Clinical Laboratory Automation
- Place of Presentation
  Seoul, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-23390149
[Presentation] Recent advances of biomarker discovery in biological fluids by using Mass Spectrometry2012
- Author(s)
  Saito K
- Organizer
  8th International Conference of Clinical Laboratory Automation
- Place of Presentation
  Seoul, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-23650417
[Presentation] 高脂血症治療剤による培養細胞に対するCa^<2+>放出効果の基礎的検討2010
- Author(s)
  服部高幸、竹村正男、太田浩敏、大澤陽介、金森寛充、伊藤弘康、斎藤邦明、清島満
- Organizer
  第49回日本臨床検査医学会東海・北陸支部総会第320回日本臨床化学会東海北陸支部例会連合大会
- Place of Presentation
  名古屋市
- Year and Date
  2010-03-14
- Data Source
  KAKENHI-PROJECT-21390179
[Presentation] Ca2+releasing effect of stains on human CD19+primary B cells.2010
- Author(s)
  Hattori T, Saito K, Takemura M, Ito H, Ohta H, Wada H, Sei Y, Kawamura M, Seishima M
- Organizer
  第42回日本動脈硬化学会総会・学術集会
- Place of Presentation
  岐阜市
- Year and Date
  2010-06-15
- Data Source
  KAKENHI-PROJECT-21390179
[Presentation] Ca^<2+> releasing effect of statins on human CD19+ primary B cells2010
- Author(s)
  Hattori T, Saito K, Takemura M, Ito H, Ohta H, Wada H, Sei Y, Kawamura M, Seishima M
- Organizer
  第42回日本動脈硬化学会総会・学術集会
- Place of Presentation
  岐阜市
- Year and Date
  2010-06-15
- Data Source
  KAKENHI-PROJECT-21390179
[Presentation] 高脂血症治療剤による培養細胞に対するCa2+放出効果の基礎的検討2010
- Author(s)
  服部高幸、竹村正男、太田浩敏、大澤陽介、金森寛充、伊藤弘康、斎藤邦明、清島満
- Organizer
  第49回日本臨床検査医学会東海・北陸支部総会第320回日本臨床化学会東海・北陸支部例会連合大会
- Place of Presentation
  名古屋
- Year and Date
  2010-03-14
- Data Source
  KAKENHI-PROJECT-21390179

1. SEISHIMA Mitsuru (10171315)

# of Collaborated Projects: 17 results

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Saito Kuniaki 齋藤 邦明

SAITOU Kuniaki 齋藤 邦明

SAITO Kuniaki 斉藤 邦明

斉藤 邦明 サイトウ クニアキ

齋藤 邦昭 サイトウ クニアキ

齋藤 邦明 サイトウ クニアキ

SAITOH Kunio 斎藤 邦明

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Relationship between changes in amino acid metabolism during pregnancy and postpartum depression.Principal Investigator

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Tryptophan metabolic profile is effective for preemptive medicine in depression symptomsPrincipal Investigator

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Increased serum GP88 (Progranulin) concentrations in rheumatoid arthritis.Principal Investigator

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Increases in Tryptophan-kynurenine pathway metabolism following interferon-induced depressionPrincipal Investigator

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Studies on thescale for stress induced emotional changesPrincipal Investigator

Saito Kuniaki 齋藤邦明

SAITOU Kuniaki 齋藤邦明

SAITO Kuniaki 斉藤邦明

斉藤邦明サイトウクニアキ

齋藤邦昭サイトウクニアキ

齋藤邦明サイトウクニアキ

SAITOH Kunio 斎藤邦明