ISHIHARA Shunji 石原俊治

Researcher Number	80263531
Other IDs
Affiliation (Current)	2025: 島根大学, 学術研究院医学・看護学系, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 島根大学, 学術研究院医学・看護学系, 教授 2018: 島根大学, 学術研究院医学・看護学系, 准教授 2008 – 2017: Shimane University, 医学部, 准教授 2003 – 2007: 島根大学, 医学部, 講師 2006: Shimane University, medicine, Assistant professor, 医学部, 助教授 2002: Shimane Medical University, Assistant Professor, 医学部, 講師 1998 – 2001: 島根医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Gastroenterology / Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 90130:Medical systems-related / Basic Section 57080:Social dentistry-related / Gastroenterology
Keywords	Principal Investigator 自然免疫 / MD-2 / IL-10 / 制御性B細胞 / 炎症性腸疾患 / クローン病 / innate immunity / Toll受容体 / H.pylori / アデノシン三リン酸 … More / Tollip / A20 / MyD88 / 潰瘍性大腸炎 / Toll-like receptor / 腸管免疫 / Ahr / Clec4a4 / 制御性好酸球 / 好酸球性胃腸炎 / 制御性T細胞 / 腸管粘膜透過性 / アデノシン三リン酸（ATP） / P2X7受容体 / Crohn病 / ATP / IRAK-M / negative feedback system / ネガティブフィードバック調整 / RAK-M / ネガティブフィードバック / Toll-like receptor 4 / Innate immunity / H.pylori感染 / toll-like receptor-4 / ヘリコバクタ・ピロリ / toll-like receptor 4 / H. pylori / ECL cell / H.pyvlori / TLR4 / H.Pylori / Toll like receptor / ＩＬ-10 / アポトーシス / クローン病モデルマウス / MF-кB / MF-κB / Tool受容体 / NF-κB / MFG-E8 / apoptosis / 萎縮性胃炎 / H.phylori / Fas ligand / Fas … More Except Principal Investigator Cdx2 / Barrett食道 / 好酸球性食道炎 / 胆汁酸 / アレルギー / TRAIL / Cdx 2 / Reg gene / COX-2 / Barrett's esophagus / methylation specific PCR / methylation / DNA / 腸管オルガノイド / 好酸球性胃腸炎 / ファイバープローブ / エオジノフィルペルオキダーゼ / ラマンプローブ / エオジノフィルペルオキシダーゼ / 非生検的診断法 / ラマン分光法 / oral bacteria / collagen binding protein / Streptcoccus mutans / 口腔内細菌叢 / Treponema forsythia / Streptococcus mutans / Neisseria / streptococcus mutans / 歯周病原因性菌 / 経皮感作 / 制御性B細胞（Breg) / MHG-E8 / 大腸癌治療 / 制御性B細胞（Breg） / IL-10 / MFG-E8 / 制御性B細胞 / 腸管免疫 / 腫瘍免疫 / invasion / apoptosis / Cholangiocarcinoma / cancer / 癌浸潤能 / アポトーシス / 胆道疾患 / 癌 / Hypoxia inducible factor / Mucin phenotype / Carcinogenesis / Barrett's cancer / Crystal violet色素内視鏡 / Fatty acid synthetase / hypoxia induible factor / Reggene / hypoxia inducible factor / ムチン形質 / 発癌 / Barrett腺癌 / dehydrocholic acid / cholic acid / bile acid / CdX2 / Dehydrocholic acid / Cholic acid / TGF-β1 / Colon mucosa / TGFβ1 / 大腸粘膜 / KLF4 / 食道炎 / リンパ球 / 胃酸 Less

A study regarding a novel anti-inflammatory eosinophil subset on pathogenesis of eosiophilic gastroenteritisPrincipal Investigator
- Principal Investigator
  
  石原俊治
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Shimane University
腸粘膜の透過性制御に着目したヒト腸管疑似モデルによる好酸球性胃腸炎の病態解明
- Principal Investigator
  
  大嶋直樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Shimane University
Analysis of B cell functions regulating intestinal mucosal permeability on the pathogenesis of Crohn's diseasePrincipal Investigator
- Principal Investigator
  
  Ishihara Shunji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Shimane University
Mechanism of eosinophilic esophagitis focusing on the immune response of the esophagus-skin interface via percutaneous sensitisation.
- Principal Investigator
  
  Oshima Naoki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Shimane University
A research for investigating the mechanism how highly pathogenic oral bacteria induces eosinophilic esophagitis.
- Principal Investigator
  
  Niibayashi Tomomi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Shimane University
Development of a low invasive and non-bioptic diagnostic technique for eosinophil esophagitis by Raman spectroscopy
- Principal Investigator
  
  Yamamoto Tatsuyuki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Shimane University
Elucidation of a novel mechanism leading regulatory B cells dysfunction of in Crohn's diseasePrincipal Investigator
- Principal Investigator
  
  Ishihara Shunji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Shimane University
Avoidance of milk fat globule-epidermal growth factor-8 (MFG-E8) tumor immunity via regulatory B cells and application of mechanism for colon cancer therapy
- Principal Investigator
  
  kawashima Kousaku
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Shimane University
Elucidation of the molecular mechanism of induction/activation of regulatory B cells and its application to regulation of intestinal inflammationPrincipal Investigator
- Principal Investigator
  
  Ishihara Shunji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Shimane University
Role of regulatory B cells in chronic intestinal inflammation: association with pathogenesis of Crohn's diseasePrincipal Investigator
- Principal Investigator
  
  ISHIHARA Shyunji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Shimane University
食道幹細胞を用いたバレット食道発生機序の解明
- Principal Investigator
  
  数森秀章
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Shimane University
Investigation regarding the role of MFG-E8 on NF-κB-dependent intestinal inflammation : Development of a new anti-inflammatory targeting MFG-E8Principal Investigator
- Principal Investigator
  
  ISHIHARA Shunji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Shimane University
食道幹細胞培養モデルを用いたバレット食道の発生機構の解明
- Principal Investigator
  
  KAZUMORI Hideaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Shimane University
Evaluation of the role of TRAIL induced cell migration and invasion in cholangioma cells
- Principal Investigator
  
  ISHIMURA Norihisa
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Shimane University
Role of negative regulators for Toll-like receptor-dependent signaling in gut innate immune systemPrincipal Investigator
- Principal Investigator
  
  ISHIHARA Shunji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Shimane University
Roles of growth factors and transcriptional factors in the pathophysiology of Barrett's esophagus and Barrett's carcinogenesis
- Principal Investigator
  
  AMANO Yuji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Shimane University
Establishment of Barrett's esophagus model using stem cell of esophagus
- Principal Investigator
  
  KAZUMORI Hideaki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Shimane University
Essential role of MD-2 in TLR4-dependent signaling during Helicobacter pylori- associated gastritisPrincipal Investigator
- Principal Investigator
  
  ISHIHARA Shunji
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Shimane University
  Shimane Medical University
Role of MD-2 in Tool-like receptor 4-dependent signaling in Helicobacter-pylori-associated gastritisPrincipal Investigator
- Principal Investigator
  
  ISHIHARA Shunji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Shimane Medical University
Methylation in the promoter of TGF-β1 gene in colon mucosaPrincipal Investigator
- Principal Investigator
  
  ISHIHARA Shunnji, 福田亮
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Shimane Medical University
ヘリコバクター胃炎における胃粘膜萎縮発生機序の解明-Fasを介したアポトーシスの関与-Principal Investigator
- Principal Investigator
  
  石原俊治
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Shimane Medical University

[Book] MFG-E8 and Inflammation:Anti-Inflammatory Role of MFG-E8 in the Intestinal Tract2014
- Author(s)
  Ishihara S, Kusunoki R, Kinoshita Y
- Publisher
  Springer Science+Business Media
- Data Source
  KAKENHI-PROJECT-26460970
[Book] Methods Mol Biol. :TGF-β detection and measurement in murine B cells: pros and cons of the different techniques2014
- Author(s)
  Mishima Y, Ishihara S, Hansen JJ, Kinoshita Y
- Publisher
  Human Press
- Data Source
  KAKENHI-PROJECT-26460970
[Journal Article] Gastric Metastasis from Salivary Duct Carcinoma Mimicking Scirrhous Gastric Cancer2024
- Author(s)
  Kishimoto Kenichi、Shibagaki Kotaro、Araki Asuka、Murakami Kotaro、Takahashi Yusuke、Kotani Satoshi、Oka Akihiko、Yazaki Tomotaka、Fukuba Nobuhiko、Mishima Yoshiyuki、Oshima Naoki、Kawashima Kousaku、Ishimura Norihisa、Kadota Kyuichi、Ishihara Shunji
- Journal Title
  
  Intern. Med.
  
  Volume: 63 Issue: 3 Pages: 373-378
- DOI
  10.2169/internalmedicine.1965-23
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2024-02-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08542
[Journal Article] Predictive Factors for Efficacy of Oral Tacrolimus Induction Therapy in Moderate to Severe Ulcerative Colitis Patients: Large Multicenter Retrospective Cohort Study2023
- Author(s)
  Oshima Naoki、Hiraoka Sakiko、Hayashi Ryohei、Takahashi Sakuma、Ishii Manabu、Hashimoto Shinichi、Yashima Kazuo、Igawa Shoko、Inokuchi Toshihiro、Ueno Yoshitaka、Inaba Tomoki、Matsumoto Hiroshi、Kawashima Kousaku、Takami Taro、Isomoto Hajime、Shiotani Akiko、Tanaka Shinji、Ishihara Shunji
- Journal Title
  
  Inflammatory Bowel Diseases
  
  Volume: in press Issue: 7 Pages: 1087-1093
- DOI
  10.1093/ibd/izad150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08542
[Journal Article] Development of In-situ Raman Diagnosis Technique of Eosinophil Esophagitis2023
- Author(s)
  Riki　Zakaria,　Bibin.B.　Andria,　Takumu　Watanabe, AnisaMaryani, Pradjna N.Paramitha, Yasmi P.Kuntana, Yukako Kusaka, Hemanth Noothalapati, Keita Iwasaki, Naoki Oshima, Kosuke Hashimoto, Hiroko Matsuyoshi, Shunji Ishihara, Tatsuyuki Yamamoto, Hidetoshi Sato
- Journal Title
  
  Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
  
  Volume: 285 Pages: 121804-121804
- DOI
  10.1016/j.saa.2022.121804
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04486, KAKENHI-PROJECT-21K18081, KAKENHI-PROJECT-22K08542
[Journal Article] Interim analysis of a multicenter registry study of COVID-19 patients with inflammatory bowel disease in Japan (J-COSMOS)2022
- Author(s)
  Nakase Hiroshi、Hayashi Yuki、Hirayama Daisuke、、Ishihara Shunji、et all、J-COSMOS group
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 57 Issue: 3 Pages: 174-184
- DOI
  10.1007/s00535-022-01851-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07961, KAKENHI-PROJECT-22K07978, KAKENHI-PROJECT-22K08019
[Journal Article] Long-lasting renal dysfunction following tacrolimus induction therapy in ulcerative colitis patients2022
- Author(s)
  Cha Na、Oshima Naoki、Kishimoto Kenichi、Kotani Satoshi、Okimoto Eiko、Yazaki Tomotaka、Sonoyama Hiroki、Oka Akihiko、Mishima Yoshiyuki、Shibagaki Kotaro、Tobita Hiroshi、Kawashima Kousaku、Ishimura Norihisa、Ishihara Shunji
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 70 Issue: 3 Pages: 297-303
- DOI
  10.3164/jcbn.21-139
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07961, KAKENHI-PROJECT-22K08542, KAKENHI-PROJECT-19K08907
[Journal Article] Heterotopic Gastric Mucosa in Middle Esophagus Complicated with Esophageal Ulcers2022
- Author(s)
  Kishimoto Kenichi、Shibagaki Kotaro、Nonomura Saya、Sumi Shohei、Fukuda Naoki、Takahashi Yusuke、Kotani Satoshi、Okimoto Eiko、Oshima Naoki、Kawashima Kousaku、Ishimura Norihisa、Ishihara Shunji
- Journal Title
  
  Intern. Med.
  
  Volume: 61 Issue: 18 Pages: 2735-2740
- DOI
  10.2169/internalmedicine.8705-21
- NAID
  130008164558
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2022-09-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08542, KAKENHI-PROJECT-19K08907
[Journal Article] Induction of mucosal healing by intensive granulocyte/monocyte adsorptive apheresis (GMA) without use of corticosteroids in patients with ulcerative colitis: long-term remission maintenance after induction by GMA and efficacy of GMA re-treatment upon relapse2022
- Author(s)
  Fukuchi Takumi、Kawashima Kousaku、Koga Hideaki、Utsunomiya Ran、Sugiyama Kohei、Shimazu Keiji、Eguchi Takaaki、Ishihara Shunji
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 70 Issue: 2 Pages: 197-204
- DOI
  10.3164/jcbn.21-112
- NAID
  130008165962
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07961
[Journal Article] Low Fecal Calprotectin Predicts Histological Healing in Patients with Ulcerative Colitis with Endoscopic Remission and Leads to Prolonged Clinical Remission2022
- Author(s)
  Kawashima Kousaku、Oshima Naoki、Kishimoto Kenichi、Kataoka Masatoshi、Fukunaga Mai、Kotani Satoshi、Sonoyama Hiroki、Oka Akihiko、Mishima Yoshiyuki、Kazumori Hideaki、Ishikawa Noriyoshi、Araki Asuka、Ishihara Shunji
- Journal Title
  
  Inflammatory Bowel Diseases
  
  Volume: 29 Issue: 3 Pages: 359-366
- DOI
  10.1093/ibd/izac095
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07961, KAKENHI-PROJECT-22K08542, KAKENHI-PROJECT-19K08907
[Journal Article] The Simultaneous Onset of Pancreatitis and Colitis as Immune-related Adverse Events in a Patient Receiving Nivolumab Treatment for Renal Cell Carcinoma2022
- Author(s)
  Yazaki Tomotaka、Moriyama Ichiro、Tobita Hiroshi、Sonoyama Hiroki、Okimoto Eiko、Oka Akihiko、Mishima Yoshiyuki、Oshima Naoki、Shibagaki Kotaro、Kawashima Kousaku、Ishimura Norihisa、Nagami Taichi、Maruyama Riruke、Shiina Hiroaki、Ishihara Shunji
- Journal Title
  
  Intern. Med.
  
  Volume: 61 Issue: 10 Pages: 1485-1490
- DOI
  10.2169/internalmedicine.7911-21
- NAID
  130008114221
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2022-05-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08542, KAKENHI-PROJECT-19K08907
[Journal Article] Discontinuation of infliximab in patients with ulcerative colitis in remission (HAYABUSA)： a multicentre, open-label, randomised controlled trial.2021
- Author(s)
  Kobayashi T, Motoya S, Nakamura S, Yamamoto T, Nagahori M, Tanaka S, Hisamatsu T, Hirai F, Nakase H, Watanabe K, Matsumoto T, Tanaka M, Abe T, Suzuki Y, Watanabe M, Hibi T; HAYABUSA Study Group
- Journal Title
  
  Lancet Gastroenterol Hepatol.
  
  Volume: 6 Issue: 6 Pages: 429-437
- DOI
  10.1016/s2468-1253(21)00062-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-21K07961
[Journal Article] Genetic Background of Mesalamine-induced Fever and Diarrhea in Japanese Patients with Inflammatory Bowel Disease2021
- Author(s)
  Suzuki K, Kakuta Y, Naito T, Takagawa T, Hanai H, Araki H, Sasaki Y, Sakuraba H, Sasaki M, Hisamatsu T, Motoya S, Matsumoto T, Onodera M, Ishiguro Y, Nakase H, et al.
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: - Issue: 1 Pages: 21-31
- DOI
  10.1093/ibd/izab004
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02799, KAKENHI-PROJECT-18K15740, KAKENHI-PROJECT-21K07961, KAKENHI-PROJECT-20K08304
[Journal Article] Juvenile social defeat stress exposure favors in later onset of irritable bowel syndrome-like symptoms in male mice2021
- Author(s)
  Matsumoto Kenjiro、Takata Kana、Yamada Daisuke、Usuda Haruki、Wada Koichiro、Tada Maaya、Mishima Yoshiyuki、Ishihara Shunji、Horie Syunji、Saitoh Akiyoshi、Kato Shinichi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 16276-16276
- DOI
  10.1038/s41598-021-95916-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07109, KAKENHI-PROJECT-19H04032, KAKENHI-PROJECT-21K07961
[Journal Article] Primary Extragastrointestinal Stromal Tumor of Greater Omentum with Intraperitoneal Bleeding2021
- Author(s)
  Kataoka Masatoshi、Saitoh Tsukasa、Kawashima Kousaku、Yazaki Tomotaka、Sonoyama Hiroki、Okimoto Eiko、Oka Akihiko、Mishima Yoshiyuki、Mishiro Tsuyoshi、Oshima Naoki、Shibagaki Kotaro、Tobita Hiroshi、Moriyama Ichiro、Ishimura Norihisa、Nagase Mamiko、Hirahara Noriyuki、Tajima Yoshitsugu、Ishihara Shunji
- Journal Title
  
  Intern. Med.
  
  Volume: 60 Issue: 21 Pages: 3413-3419
- DOI
  10.2169/internalmedicine.6519-20
- NAID
  130008110287
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2021-11-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08907, KAKENHI-PROJECT-21K08753
[Journal Article] Enteric Microbiota-Mediated Serotonergic Signaling in Pathogenesis of Irritable Bowel Syndrome2021
- Author(s)
  Mishima Yoshiyuki、Ishihara Shunji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 19 Pages: 10235-10235
- DOI
  10.3390/ijms221910235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07961
[Journal Article] Intestinal-type gastric dysplasia in Helicobacter pylori-na?ve patients2021
- Author(s)
  Shibagaki Kotaro、Itawaki Ayako、Miyaoka Yoichi、Kishimoto Kenichi、Takahashi Yusuke、Kotani Satoshi、Mishiro Tsuyoshi、Oshima Naoki、Kawashima Kousaku、Ishimura Norihisa、Onuma Hideyuki、Nagasaki Makoto、Nagase Mamiko、Araki Asuka、Kadota Kyuichi、Kushima Ryoji、Ishihara Shunji
- Journal Title
  
  Virchows Archiv
  
  Volume: 480 Issue: 4 Pages: 783-792
- DOI
  10.1007/s00428-021-03237-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08907
[Journal Article] Differential gene expression analysis of dasatinib-induced colitis in a patient with chronic myeloid leukemia followed for 3?years: a case report2021
- Author(s)
  Oshima Naoki、Mishima Yoshiyuki、Shibagaki Kotaro、Kawashima Kousaku、Ishimura Norihisa、Ikejiri Fumiyoshi、Onishi Chie、Okada Takahiro、Inoue Masaya、Moriyama Ichiro、Suzumiya Junji、Kinoshita Yoshikazu、Ishihara Shunji
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 21 Issue: 1 Pages: 19-19
- DOI
  10.1186/s12876-020-01584-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09383, KAKENHI-PROJECT-18K07971, KAKENHI-PROJECT-19K08907
[Journal Article] Intermittent Purpura Development Associated with Leukocytoclastic Vasculitis Induced by Infliximab for Crohn's Disease2021
- Author(s)
  Kishimoto Kenichi、Kawashima Kousaku、Fukunaga Mai、Kotani Satoshi、Sonoyama Hiroki、Oka Akihiko、Mishima Yoshiyuki、Oshima Naoki、Ishimura Norihisa、Ishikawa Noriyoshi、Maruyama Riruke、Ishihara Shunji
- Journal Title
  
  Intern. Med.
  
  Volume: 60 Issue: 3 Pages: 385-389
- DOI
  10.2169/internalmedicine.5340-20
- NAID
  130007979732
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2021-02-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09383, KAKENHI-PROJECT-18K07971, KAKENHI-PROJECT-19K08907
[Journal Article] Detection and Quantification of Transforming Growth Factor-β1 Produced by Murine B Cells: Pros and Cons of Different Techniques2021
- Author(s)
  Mishima Yoshiyuki、Oka Akihiko、Ishihara Shunji
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 2270 Pages: 113-124
- DOI
  10.1007/978-1-0716-1237-8_7
- ISBN
  9781071612361, 9781071612378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07971
[Journal Article] Comparison of dapagliflozin and teneligliptin in nonalcoholic fatty liver disease patients without type 2 diabetes mellitus: a prospective randomized study2021
- Author(s)
  Tobita Hiroshi、Yazaki Tomotaka、Kataoka Masatoshi、Kotani Satoshi、Oka Akihiko、Mishiro Tsuyoshi、Oshima Naoki、Kawashima Kousaku、Ishimura Norihisa、Naora Kohji、Sato Shuichi、Ishihara Shunji
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 68 Issue: 2 Pages: 173-180
- DOI
  10.3164/jcbn.20-129
- NAID
  130007993437
- ISSN
  0912-0009, 1880-5086
- Year and Date
  2021-03-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08907
[Journal Article] Comorbid irritable bowel syndrome symptoms and headache have greater association with anxiety than depression2020
- Author(s)
  Kawashima Kousaku、Fukuba Nobuhiko、Uemura Yusuke、Ota Kuniko、Kazumori Hideaki、Sonoyama Hiroki、Oka Akihiko、Tada Yasumasa、Mishima Yoshiyuki、Oshima Naoki、Yuki Takafumi、Katsube Tomoko、Kinoshita Yoshikazu、Ishihara Shunji
- Journal Title
  
  Medicine
  
  Volume: 99 Issue: 47 Pages: e23059-e23059
- DOI
  10.1097/md.0000000000023059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08907, KAKENHI-PROJECT-17K09383
[Journal Article] Prevalence of functional dyspepsia-like symptoms in ulcerative colitis patients in clinical remission and overlap with irritable bowel syndrome-like symptoms2020
- Author(s)
  Kotani Satoshi、Fukuba Nobuhiko、Kawashima Kousaku、Mishima Yoshiyuki、Sonoyama Hiroki、Okimoto Eiko、Tada Yasumasa、Oka Akihiko、Tamagawa Yuji、Oshima Naoki、Mishiro Tsuyoshi、Tobita Hiroshi、Shibagaki Kotaro、Moriyama Ichiro、Ishimura Norihisa、Kushiyama Yoshinori、Fujishiro Hirofumi、Ishihara Shunji
- Journal Title
  
  Scandinavian Journal of Gastroenterology
  
  Volume: 55 Issue: 5 Pages: 560-564
- DOI
  10.1080/00365521.2020.1761998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08907, KAKENHI-PROJECT-19K23945, KAKENHI-PROJECT-17K09383
[Journal Article] Ten-year follow-up study of linear immunoglobulin A dermatosis complicated with ulcerative colitis2020
- Author(s)
  Sonoyama H, Mishima Y, Ishihara S, Oshima N, Moriyama I, Kawashima K, Chinuki Y, Morita E, Kinoshita Y
- Journal Title
  
  Clin J Gastroenterol
  
  Volume: 13 Issue: 2 Pages: 164-169
- DOI
  10.1007/s12328-019-01047-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09383, KAKENHI-PROJECT-18K07971
[Journal Article] Prospective multicenter study of the esophageal triamcinolone acetonide‐filling method in patients with subcircumferential esophageal endoscopic submucosal dissection2020
- Author(s)
  Shibagaki Kotaro、Yuki Takafumi、Taniguchi Hideaki、Aimi Masahito、Miyaoka Yoichi、Yuki Mika、Ishimura Norihisa、Oshima Naoki、Mishiro Tsuyoshi、Tamagawa Yuji、Mikami Hironobu、Izumi Daisuke、Yamashita Noritsugu、Sato Shuichi、Ishihara Shunji、Kinoshita Yoshikazu
- Journal Title
  
  Digestive Endoscopy
  
  Volume: 32 Issue: 3 Pages: 355-363
- DOI
  10.1111/den.13496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08907, KAKENHI-PROJECT-19K23945
[Journal Article] Therapeutic options for Crohn's disease2020
- Author(s)
  Ishihara S, Mishima Y, Kawashima K
- Journal Title
  
  Shimane journal of medical science
  
  Volume: 37 Pages: 45-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09383
[Journal Article] Molecular Mechanisms of Microbiota-Mediated Pathology in Irritable Bowel Syndrome2020
- Author(s)
  Mishima Yoshiyuki、Ishihara Shunji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 22 Pages: 8664-8664
- DOI
  10.3390/ijms21228664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07971
[Journal Article] 【炎症性腸疾患の新規治療とその適応】炎症性腸疾患における新規治療の現状2020
- Author(s)
  石原　俊治，三島　義之，岡　　明彦，大嶋　直樹，川島　耕作
- Journal Title
  
  消化器・肝臓内科
  
  Volume: 8 Pages: 219-227
- Data Source
  KAKENHI-PROJECT-19K08907
[Journal Article] 【何をしている好酸球?好酸球性消化管疾患のメカニズム】好酸球性胃腸炎の病態・診断・治療2020
- Author(s)
  大嶋　直樹，石原　俊治
- Journal Title
  
  消化器病サイエンス
  
  Volume: 4 Pages: 99-102
- Data Source
  KAKENHI-PROJECT-19K08907
[Journal Article] Eosinophilic Granulomatosis with Polyangiitis Initially Diagnosed as Eosinophilic Gastroenteritis2020
- Author(s)
  Itawaki Ayako、Okada Mayumi、Kawashima Kousaku、Okimoto Eiko、Sonoyama Hiroki、Mishima Yoshiyuki、Oshima Naoki、Ishimura Norihisa、Moriyama Mayuko、Murakawa Yohko、Araki Asuka、Ishikawa Noriyoshi、Maruyama Riruke、Ishihara Shunji、Kinoshita Yoshikazu
- Journal Title
  
  Intern. Med.
  
  Volume: 59 Issue: 8 Pages: 1029-1033
- DOI
  10.2169/internalmedicine.3391-19
- NAID
  130007831687
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2020-04-15
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09383, KAKENHI-PROJECT-18K07939
[Journal Article] Expert opinions on the current therapeutic management of inflammatory bowel disease during the COVID-19 pandemic: Japan IBD COVID-19 taskforce, intractable diseases, the health and labor sciences research.2020
- Author(s)
  akase H, Matsumoto T, Matsuura M, Iijima H, Matsuoka K, Ohmiya N, Ishihara S, Hirai F, Wagatsuma K, Yokoyama Y, Hisamatsu T.
- Journal Title
  
  Digestion
  
  Volume: - Issue: 5 Pages: 1-9
- DOI
  10.1159/000510502
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02799, KAKENHI-PROJECT-18K07947, KAKENHI-PROJECT-18K07971
[Journal Article] Non-adherence to Medications in Pregnant Ulcerative Colitis Patients Contributes to Disease Flares and Adverse Pregnancy Outcomes2020
- Author(s)
  Watanabe C、Nagahori M、Fujii T、Yokoyama K、Yoshimura N、Kobayashi T、Yamagami H、Kitamura K、Takashi K、Nakamura S、Naganuma M、Ishihara S、Esaki M、Yonezawa M、Kunisaki R、Sakuraba A、Kuji N、Miura S、Hibi T、Suzuki Y、Hokari R
- Journal Title
  
  Digestive Diseases and Sciences
  
  Volume: 66 Issue: 2 Pages: 577-586
- DOI
  10.1007/s10620-020-06221-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07971
[Journal Article] 【今月のテーマ（総説）】ウステキヌマブによるクローン病の治療―有効性と安全性からみた位置付け―2019
- Author(s)
  石原俊治、川島耕作、木下芳一
- Journal Title
  
  日本消化器病学会雑誌
  
  Volume: 116 Pages: 216-223
- Data Source
  KAKENHI-PROJECT-18K07971
[Journal Article] Capabilities of fecal calprotectin and blood biomarkers as surrogate endoscopic markers according to ulcerative colitis disease type2019
- Author(s)
  Sonoyama H, Kawashima K, Ishihara S, Kotani S, Fukuba N, Oka A, Kusunoki R, Tada Y, Mishima Y, Oshima N, Moriyama I, Yuki T, Onishi K, Kinoshita Y
- Journal Title
  
  J Clin Biochem Nutr
  
  Volume: in press
- NAID
  130007641427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07971
[Journal Article] Interleukin-33 delays recovery of mucosal inflammation via downregulation of homeostatic ABCG5/8 in the colon2019
- Author(s)
  Mishima Yoshiyuki、Sonoyama Hiroki、Ishihara Shunji、Oshima Naoki、Moriyama Ichiro、Kawashima Kousaku、Kinoshita Yoshikazu
- Journal Title
  
  Laboratory Investigation
  
  Volume: 100 Issue: 3 Pages: 491-502
- DOI
  10.1038/s41374-019-0329-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09383, KAKENHI-PROJECT-18K07971
[Journal Article] Capabilities of fecal calprotectin and blood biomarkers as surrogate endoscopic markers according to ulcerative colitis disease type2019
- Author(s)
  Sonoyama H, Kawashima K, Ishihara S, Kotani S, Fukuba N, Oka A, Kusunoki R, Tada Y, Mishima Y, Oshima N, Moriyama I, Yuki T, Onishi K, Kinoshita Y
- Journal Title
  
  J Clin Biochem Nutr
  
  Volume: in press
- NAID
  130007641427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09383
[Journal Article] ウステキヌマブによるクローン病の治療―有効性と安全性からみた位置付け―2019
- Author(s)
  石原俊治、川島耕作、木下芳一
- Journal Title
  
  日本消化器病学会雑誌
  
  Volume: 116 Pages: 216-223
- NAID
  130007609036
- Data Source
  KAKENHI-PROJECT-17K09383
[Journal Article] Capabilities of fecal calprotectin and blood biomarkers as surrogate endoscopic markers according to ulcerative colitis disease type2019
- Author(s)
  Sonoyama Hiroki、Kawashima Kousaku、Ishihara Shunji、Kotani Satoshi、Fukuba Nobuhiko、Oka Akihiko、Kusunoki Ryusaku、Tada Yasumasa、Mishima Yoshiyuki、Oshima Naoki、Moriyama Ichiro、Yuki Takafumi、Onishi Koji、Kinoshita Yoshikazu
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 64 Issue: 3 Pages: 265-270
- DOI
  10.3164/jcbn.18-92
- NAID
  130007641427
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09383, KAKENHI-PROJECT-18K07971
[Journal Article] Irritable Bowel Syndrome-Like Symptoms in Ulcerative Colitis Patients in Clinical Remission: Association with Residual Colonic Inflammation2018
- Author(s)
  Ishihara Shunji、Kawashima Kousaku、Fukuba Nobuhiko、Tada Yasumasa、Kotani Satoshi、Mishima Yoshiyuki、Oshima Naoki、Kinoshita Yoshikazu
- Journal Title
  
  Digestion
  
  Volume: 99 Issue: 1 Pages: 46-51
- DOI
  10.1159/000494412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09383, KAKENHI-PROJECT-18K07971
[Journal Article] Serum amyloid A level correlated with endoscopic findings in patients with Crohn’s disease?Possible biomarker for evaluating mucosal healing2018
- Author(s)
  Ishihara Shunji、Tada Yasumasa、Kawashima Kousaku、Kataoka Masatoshi、Sonoyama Hiroki、Yamashita Noritsugu、Oka Akihiko、Kusunoki Ryusaku、Fukuba Nobuhiko、Mishima Yoshiyuki、Oshima Naoki、Moriyama Ichiro、Yuki Takafumi、Kinoshita Yoshikazu
- Journal Title
  
  Digestive and Liver Disease
  
  Volume: 50 Issue: 6 Pages: 553-558
- DOI
  10.1016/j.dld.2017.12.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09383, KAKENHI-PROJECT-18K07971
[Journal Article] Bile acids induce Delta-like 1 expression via Cdx2-dependent pathway in the development of Barrett's esophagus.2016
- Author(s)
  Tamagawa Y, Ishimura N, Uno G, Aimi M, Oshima N, Yuki T, Sato S, Ishihara S, Kinoshita Y
- Journal Title
  
  Laboratory Investigation
  
  Volume: 96 Issue: 3 Pages: 325-337
- DOI
  10.1038/labinvest.2015.137
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460937, KAKENHI-PROJECT-26460970
[Journal Article] Recent Progress in the Research of Eosinophilic Esophagitis and Gastroenteritis.2016
- Author(s)
  Kinoshita Y, Ishimura N, Oshima N, Mikami H, Okimoto E, Jiao DJ, Ishihara S.
- Journal Title
  
  Digestion
  
  Volume: 93 Issue: 1 Pages: 7-12
- DOI
  10.1159/000441668
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460937, KAKENHI-PROJECT-25460928, KAKENHI-PROJECT-15H04763, KAKENHI-PROJECT-26460970, KAKENHI-PROJECT-26870378
[Journal Article] Eosinophilic Esophagitis, Eosinophilic Gastroenteritis, and Eosinophilic Colitis: Common Mechanisms and Differences between East and West2016
- Author(s)
  Ishihara S, Kinoshita Y, Schoepfer A.
- Journal Title
  
  Inflammatory Intestinal Diseases
  
  Volume: 1 Issue: 2 Pages: 63-69
- DOI
  10.1159/000445131
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04763, KAKENHI-PROJECT-26460970
[Journal Article] Therapeutic Efficacy of pH-Dependent Release Formulation of Mesalazine on Active Ulcerative Colitis Resistant to Time-Dependent Release Formulation: Analysis of Fecal Calprotectin Concentration2016
- Author(s)
  Kawashima K, Ishihara S, Yuki T, Onishi K, Kushiyama Y, Fujishiro H, Miyaoka Y, Yuki M, Komazawa Y, Tanimura T, Sonoyama H, Tada Y, Kusunoki R, Oka A, Fukuba N, Oshima N, Moriyama I, Kinoshita Y
- Journal Title
  
  Biomed Res Int
  
  Volume: 2014 Pages: 342751-342751
- DOI
  10.1155/2014/342751
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460970
[Journal Article] Down-regulation of serotonin reuptake transporter gene expression in healing colonic mucosa in presence of remaining low grade inflammation in ulcerative colitis2016
- Author(s)
  Tada Y, Ishihara S, Kawashima K, Fukuba N, Sonoyama H, Kusunoki R, Oka A, Mishima Y, Oshima N, Moriyama I, Yuki T, Ishikawa N, Araki A, Harada Y, Maruyama R, Kinoshita Y
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 印刷中 Issue: 8 Pages: 1443-1452
- DOI
  10.1111/jgh.13268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460970
[Journal Article] Decreased Frequency of Intestinal Regulatory CD5+ B Cells in Colonic Inflammation2016
- Author(s)
  Mishima Y, Ishihara S, Oka A, Fukuba N, Oshima N, Sonoyama H, Yamashita N, Tada Y, Kusunoki R, Moriyama I, Yuki T, Kawashima K, Kinoshita Y
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 1 Pages: e0146191-e0146191
- DOI
  10.1371/journal.pone.0146191
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460970, KAKENHI-PROJECT-16K09282
[Journal Article] Fecal calprotectin level correlated with both endoscopic severity and disease extent in ulcerative colitis2016
- Author(s)
  Kawashima K, Ishihara S, Yuki T, Fukuba N, Oshima N, Kazumori H, Sonoyama H, Yamashita N, Tada Y, Kusunoki R, Oka A, Mishima Y, Moriyama I, Kinoshita Y
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 16 Issue: 1 Pages: 47-47
- DOI
  10.1186/s12876-016-0462-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460970
[Journal Article] Role of milk fat globule-epidermal growth factor 8 in colonic inflammation and carcinogenesis2015
- Author(s)
  Kusunoki R, Ishihara S, Tada Y, Oka A, Sonoyama H, Fukuba N, Oshima N, Moriyama I, Yuki T, Kawashima K, Ansary MM, Tajima Y, Maruyama R, Nabika T, Kinoshita Y
- Journal Title
  
  J Gastroenterol.
  
  Volume: Epub ahead of print
- Data Source
  KAKENHI-PROJECT-26460970
[Journal Article] Role of milk fat globule-epidermal growth factor 8 in colonic inflammation and carcinogenesis2015
- Author(s)
  Kusunoki R, Ishihara S, Tada Y, Oka A, Sonoyama H, Fukuba N, Oshima N, Moriyama I, Yuki T,Kawashima K, Ansary MM, Tajima Y, Maruyama R, Nabika T, Kinoshita Y
- Journal Title
  
  J Gastroenterol.
  
  Volume: 50 Issue: 8 Pages: 862-875
- DOI
  10.1007/s00535-014-1036-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460970, KAKENHI-PROJECT-25462112
[Journal Article] An open-label prospective randomized multicenter study of intensive versus weekly granulocyte and monocyte apheresis in active crohn's disease2015
- Author(s)
  Yoshimura N, Yokoyama Y, Matsuoka K, Takahashi H, Iwakiri R, Yamamoto T, Nakagawa T, Fukuchi T, Motoya S, Kunisaki R, Kato S, Hirai F, Ishiguro Y, Tanida S, Hiraoka S, Mitsuyama K, Ishihara S, Tanaka S, Otaka M, Osada T, Kagaya T, Suzuki Y, Nakase H, Hanai H, Watanabe K, Kashiwagi N, Hibi T
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 15 Issue: 1 Pages: 163-163
- DOI
  10.1186/s12876-015-0390-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460970
[Journal Article] Apoptotic cells ameliorate chronic intestinal inflammation by enhancing regulatory B cell function2014
- Author(s)
  Ansary Md. Mu, Ishihara S, Oka A, Kusunoki R, Oshima N, Yuki T, Kawashima K, Maegawa H, Kashiwagi N, Kinoshita Y
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 20 Issue: 12 Pages: 2308-2320
- DOI
  10.1097/mib.0000000000000240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460928, KAKENHI-PROJECT-26460970
[Journal Article] Prevalence of irritable bowel syndrome-like symptoms in ulcerative colitis patients with clinical and endoscopic evidence of remission: prospective multicenter study2014
- Author(s)
  Fukuba N, Ishihara S, Tada Y, Oshima N, Moriyama I, Yuki T, Kawashima K, Kushiyama Y, Fujishiro H, Kinoshita Y
- Journal Title
  
  Scand J Gastroenterol
  
  Volume: 49 Issue: 6 Pages: 674-680
- DOI
  10.3109/00365521.2014.898084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460970
[Journal Article] Role of regulatory B cells in chronic intestinal inflammation: association with pathogenesis of Crohn's disease2014
- Author(s)
  Oka A, Ishihara S, Mishima Y, Tada Y, Kusunoki R, Fukuba N, Yuki T, Kawashima K, Matsumoto S, Kinoshita Y
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 20 Issue: 2 Pages: 315-28
- DOI
  10.1097/01.mib.0000437983.14544.d5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590942, KAKENHI-PROJECT-25460928, KAKENHI-PROJECT-26460970
[Journal Article] Butyric acid attenuates intestinal inflammation in murine DSS-induced colitis model via milk fat globule-EGF factor 82013
- Author(s)
  Mishiro T, Kusunoki R, Otani A, Ansary M, Tongu M, Harashima N, Yamada T, Sato S, Amano Y, Itoh K, Ishihara S, Kinoshita Y
- Journal Title
  
  Lab Invest
  
  Volume: 93 Issue: 7 Pages: 834-43
- DOI
  10.1038/labinvest.2013.70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590942
[Journal Article] Development of diffuse alopecia with psoriasis-like eruption during the administration of infliximab for Crohn’s disease2013
- Author(s)
  Kawashima K, Ishihara S, Yamamoto A, Ohno Y, Fukuda K, Onishi K, Kinoshita Y
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 19 Issue: 3 Pages: E33-E34
- DOI
  10.1002/ibd.22922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590942
[Journal Article] Pathogenesis of irritable bowel syndrome - review regarding associated infection and immune activation2013
- Author(s)
  Ishihara S, Tada Y, Fukuba N, Oka A, Kusunoki R, Oshima N, Moriyama I, Yuki T, Kawashima K, Kinoshita Y
- Journal Title
  
  Digestion
  
  Volume: 87 Issue: 3 Pages: 204-11
- DOI
  10.1159/000350054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590942
[Journal Article] Successful use of maintenance infliximab for nephropathy in a patient with secondary amyloidosis complicating Crohn's disease2013
- Author(s)
  Tada Y, Ishihara S, Ito T, Matsui K, Sonoyama H, Oka A, Kusunoki R, Fukuba N, Mishima Y, Oshima N, Moriyama I, Yuki T, Kawashima K, Sato S, Adachi K, Ikeuchi H, Kinoshita Y
- Journal Title
  
  Intern Med
  
  Volume: 52 Pages: 1899-902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590942
[Journal Article] Ulcerative colitis associated with isolated unilateral hypoglossal nerve palsy2012
- Author(s)
  Kawashima K, Ishihara S, Doi K, Uemura Y, Ohno Y, Fukuda K, Onishi K, Tada Y, Oka A, Kusunoki R, Fukuba N, Yuki T, Kinoshita Y
- Journal Title
  
  Intern Med
  
  Volume: 51 Pages: 3135-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590942
[Journal Article] Intrarectal administration of milk fat globule epidermal growth factor-8 protein ameliorates murine experimental colitis2012
- Author(s)
  Otani A, Ishihara S, Aziz MM, Oshima N, Mishima Y, Moriyama I, Yuki T, Amano Y, Ansary MM, Kinoshita Y
- Journal Title
  
  Int J Mol Med
  
  Volume: 29 Pages: 349-56
- DOI
  10.3892/ijmm.2011.866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590942
[Journal Article] 炎症性腸疾患における制御性B 細胞の役割2012
- Author(s)
  岡明彦, 石原俊治, 木下芳一
- Journal Title
  
  G.I.Research
  
  Volume: 20 Pages: 479-485
- Data Source
  KAKENHI-PROJECT-23590942
[Journal Article] 炎症性腸疾患における制御性B細胞の役割2012
- Author(s)
  岡　明彦、石原俊治、木下芳一
- Journal Title
  
  G.I.Research
  
  Volume: 20 Pages: 479-485
- Data Source
  KAKENHI-PROJECT-23590942
[Journal Article] Roles of milk fat globule-epidermal growth factor 8 in intestinal inflammation2012
- Author(s)
  Kusunoki R, Ishihara S, Aziz M, Oka A, Tada Y, Kinoshita Y
- Journal Title
  
  Digestion
  
  Volume: 85 Issue: 2 Pages: 103-7
- DOI
  10.1159/000334679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590942
[Journal Article] Autophagy is required for toll-like receptor-mediated interleukin-8 production in intestinal epithelial cells2011
- Author(s)
  Li YY, Ishihara S, Aziz MM, Oka A, Kusunoki R, Tada Y, Yuki T, Amano Y, Ansary MU, Kinoshita Y
- Journal Title
  
  Int J Mol Med
  
  Volume: 27 Issue: 3 Pages: 337-44
- DOI
  10.3892/ijmm.2011.596
- Data Source
  KAKENHI-PROJECT-23590942
[Journal Article] Rare case of Takayasu's arteritis associated with Crohn's disease2011
- Author(s)
  Kusunoki R, Ishihara S, Sato M, Sumita Y, Mishima Y, Okada M, Tada Y, Oka A, Fukuba N, Oshima N, Moriyama I, Yuki T, Sato S, Amano Y, Murakawa Y, Kinoshita Y
- Journal Title
  
  Intern Med
  
  Volume: 50 Pages: 1581-5
- Data Source
  KAKENHI-PROJECT-23590942
[Journal Article] 制御性B 細胞からみたIBD 治療へのアプローチ2011
- Author(s)
  岡明彦, 石原俊治, 木下芳一
- Journal Title
  
  IBD Research
  
  Volume: 5 Pages: 259-64
- Data Source
  KAKENHI-PROJECT-23590942
[Journal Article] Autophagy is required for toll-like receptor-mediated interleukin-8 production in intestinal epithelial cells.2011
- Author(s)
  Li YY, Ishihara S, Aziz MM, Oka A, Kusunoki R, Tada Y, Yuki T, Amano Y, Ansary MU, Kinoshita Y
- Journal Title
  
  Int J Mol Med. 27
  
  Pages: 337-344
- Data Source
  KAKENHI-PROJECT-20590723
[Journal Article] Down-regulation of single immunoglobulin interleukin-1R-related molecule (SIGIRR)/TIR8 expression in intestinal epithelial cells during inflammation.2010
- Author(s)
  Kadota C, Ishihara S, et al
- Journal Title
  
  Clin Exp Immunol.
  
  Volume: 162 Pages: 348-361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590723
[Journal Article] A20 is an early responding negative regulator of Toll-like receptor 5 signalling in intestinal epithelial cells during inflammation.2010
- Author(s)
  Oshima N, Ishihara S, Rumi MA, Aziz MM, Mishima Y, Kadota C, Moriyama I, Ishimura N, Amano Y, Kinoshita Y
- Journal Title
  
  Clin Exp Immunol 159
  
  Pages: 185-198
- Data Source
  KAKENHI-PROJECT-20590723
[Journal Article] A20 is an early responding negative regulator of Toll-like receptor 5 signalling in intestinal epithelial cells during inflammation.2010
- Author(s)
  Oshima N, Ishihara S, et al
- Journal Title
  
  Clin Exp Immunol
  
  Volume: 159 Pages: 185-198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590723
[Journal Article] Decreased production of interleukin-10 and transforming growth factor-β in Toll-like receptor-activated intestinal B cells in SAMP1/Yit mice.2010
- Author(s)
  Mishima Y, Ishihara S, Aziz MM, Oka A, Kusunoki R, Otani A, Tada Y, Li YY, Moriyama I, Oshima N, Yuki T, Amano Y, Matsumoto S, Kinoshita Y
- Journal Title
  
  Immunology. 131
  
  Pages: 473-487
- Data Source
  KAKENHI-PROJECT-20590723
[Journal Article] Down-regulation of single immunoglobulin interleukin-1R-related molecule (SIGIRR)/TIR8 expression in intestinal epithelial cells during inflammation.2010
- Author(s)
  Kadota C, Ishihara S, Aziz MM, Rumi MA, Oshima N, Mishima Y, Moriyama I, Yuki T, Amano Y, Kinoshita Y
- Journal Title
  
  Clin Exp Immunol. 162
  
  Pages: 348-361
- Data Source
  KAKENHI-PROJECT-20590723
[Journal Article] Autophagy is required for toll-like receptor-mediated interleukin-8 production in intestinal epithelial cells2010
- Author(s)
  Li YY, Ishihara S, et al
- Journal Title
  
  Int J Mol Med.
  
  Volume: 27 Pages: 337-344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590723
[Journal Article] Decreased production of interleukin-10 and transforming growth factor-β in Toll-like receptor-activated intestinal B cells in SAMP1/Yit mice.2010
- Author(s)
  Mishima Y, Ishihara S, et al
- Journal Title
  
  Immunology.
  
  Volume: 131 Pages: 473-487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590723
[Journal Article] Inflammatory bowel disease : review from the aspect of genetics.2009
- Author(s)
  Ishihara S, et al
- Journal Title
  
  J Gastroenterol. 44(11)
  
  Pages: 1098-1108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590723
[Journal Article] MFG-E8 attenuates intestinal inflammation in murine experimental colitis by modulating osteopontin-dependent alphavbeta3 integrin signaling.2009
- Author(s)
  Aziz MM, Ishihara S, Mishima Y, Oshima N, Moriyama I, Yuki T, Kadowaki Y, Rumi MA, Amano Y, Kinoshita Y.
- Journal Title
  
  J Immunol 182
  
  Pages: 7222-7232
- Data Source
  KAKENHI-PROJECT-20590723
[Journal Article] Alterations of peripheral blood CD5(+) B cells in inflammatory bowel disease.2009
- Author(s)
  Mishima Y, Ishihara S, Amano Y, Oshima N, Kadota C, Otani A, Moriyama I, Li YY, Aziz M, Kinoshita Y
- Journal Title
  
  Scandinavia Journal of Gastroenterology 44
  
  Pages: 172-179
- Data Source
  KAKENHI-PROJECT-20590723
[Journal Article] Irritable bowel syndrome and inflammatory bowel disease : infectious gastroenteritis-related disorders?2009
- Author(s)
  Ishihara S, Aziz M, Oshima N, Mishima Y, Imaoka H, Moriyama I, Kinoshita Y
- Journal Title
  
  Clin J Gastroenterol 2
  
  Pages: 9-16
- Data Source
  KAKENHI-PROJECT-20590723
[Journal Article] Inflammatory bowel disease : review from the aspect of genetics.2009
- Author(s)
  Ishihara S, Aziz MM, Yuki T, Kazumori H, Kinoshita Y
- Journal Title
  
  J Gastroenterol 44
  
  Pages: 1097-1108
- Data Source
  KAKENHI-PROJECT-20590723
[Journal Article] Prolactin induces MFG-E8 production in macrophages via transcription factor C/EBPβ-dependent pathway2008
- Author(s)
  Aziz MM, Ishihara S, et al
- Journal Title
  
  Apoptosis 13
  
  Pages: 609-620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590723
[Journal Article] Decoy oligodeoxynucleotide targeting activator protein-1(AP-1) attenuates intestinal inflammation in murine experimental colitis.2008
- Author(s)
  Moriyama I, Ishihara S, et al
- Journal Title
  
  Labolatory investigation
  
  Pages: 652-663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590723
[Journal Article] Decoy oligodeoxynucleotide targeting activator protein-1(AP-1) attenuates intestinal inflammation in murine experimental colitis.2008
- Author(s)
  Moriyama I, Ishihara S, Rumi MA, Aziz MD, Mishima Yo, Oshima N, Kadota C, Kadowaki Y, Amano Y, Kinoshita Y
- Journal Title
  
  Labolatory investigation 88
  
  Pages: 652-663
- Data Source
  KAKENHI-PROJECT-20590723
[Journal Article] Prolactin induces MFG-E8 production in macrophages via transcription factor C/EBPβ-dependent pathway.2008
- Author(s)
  Aziz MM, Ishihara S, Rumi MA, Mishima Yo, Oshima N, Kadota C, Moriyama I, Li YY, Rahman FB, Otani A, Oka A, Ishimura N, Kadowaki Y, Amano Y, Kinoshita Y
- Journal Title
  
  Apoptosis 13
  
  Pages: 609-620
- Data Source
  KAKENHI-PROJECT-20590723
[Journal Article] Abnormal liver function in Crohn's disease related to location of disease lesions.2008
- Author(s)
  Fruta K, Sato S, Miyake T, Okamoto E, Ishine J, Ishihara S, Amano Y, Adachi K, Kinoshita Y.
- Journal Title
  
  Inflamm Bowel Dis 14
  
  Pages: 138-139
- Data Source
  KAKENHI-PROJECT-20590723
[Journal Article] RNA polymerase II mediated transcription from the2006
- Author(s)
  Rumi MAK, Ishihara S, et al.
- Journal Title
  
  Biochem Biophys Res Commu 339
  
  Pages: 540-547
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590643
[Journal Article] Increased expression of midkine in the rat colon during healing of experimental colitis2006
- Author(s)
  Yuki T, Ishihara S, et al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 291
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590643
[Journal Article] Epithelial toll-like receptor 5 is constitutively localized in the mouse2006
- Author(s)
  Ortega-Cava CF, Ishihara S, et al.
- Journal Title
  
  Clin Vaccine Immunol 13
  
  Pages: 132-138
- Data Source
  KAKENHI-PROJECT-17590643
[Journal Article] Therapeutic targeting of toll-like receptors in gastrointestinal inflammation.2006
- Author(s)
  Ishihara S, Rumi MAK, et al.
- Journal Title
  
  Curr Pharm Des 12
  
  Pages: 4215-4228
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590643
[Journal Article] RNA polymerase II mediated transcription from the polymerase III promoters in short hairpin RNA expression vector2006
- Author(s)
  Rumi MAK, Ishihara S, et al.
- Journal Title
  
  Biochem Biophys Res Commun 339
  
  Pages: 540-547
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590643
[Journal Article] RNA polymerase II mediated transcription from the polymerase III2006
- Author(s)
  Rumi MAK, Ishihara S, et al.
- Journal Title
  
  Biochem Biophys Res Commu 339
  
  Pages: 540-547
- Data Source
  KAKENHI-PROJECT-17590643
[Journal Article] Epithelial toll-like receptor 5 is constitutively localized in the2006
- Author(s)
  Ortega-Cava CF, Ishihara S, et al.
- Journal Title
  
  Clin Vaccine Immunol 13
  
  Pages: 132-138
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590643
[Journal Article] Epithelial toll-like receptor 5 is constitutively localized in the mouse cecum and exhibits distinctive down-regulation during experimental colitis2006
- Author(s)
  Ortega-Cava CF, Ishihara S, et al.
- Journal Title
  
  Clin Vaccine Immunol 13
  
  Pages: 132-138
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590643
[Journal Article] Therapeutic targeting of toll-like receptors in gastrointestinal2006
- Author(s)
  Ishihara S, Rumi MAK, et al.
- Journal Title
  
  Curr Pharm Des 12
  
  Pages: 4215-4228
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590643
[Journal Article] Increased expression of midkine in the rat colon during healing of2006
- Author(s)
  Yuki T, Ishihara S, et al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 291
- Data Source
  KAKENHI-PROJECT-17590643
[Journal Article] Bile acids directly augment caudal-related homeobox gene Cdx22006
- Author(s)
  Kazumori H, Ishihara S, et al.
- Journal Title
  
  Gut 55
  
  Pages: 16-25
- Data Source
  KAKENHI-PROJECT-17590643
[Journal Article] Increased expression of midkine in the rat colon during2006
- Author(s)
  Yuki T, Ishihara S, et al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 291
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590643
[Journal Article] Bile acids directly augment caudal-related homeobox gene Cdx2 expression in esophageal keratinosytes in Barrett's epithelium2006
- Author(s)
  Kazumori H, Ishihara S, et al.
- Journal Title
  
  Gut 55
  
  Pages: 16-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590643
[Journal Article] Bile acids directly augment caudal-related homeobox gene2006
- Author(s)
  Kazumori H, Ishihara S, et al.
- Journal Title
  
  Gut 55
  
  Pages: 16-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590643
[Journal Article] Essential role of MD-2 in TLR4-dependent signaling2004
- Author(s)
  Ishihara S, et al.
- Journal Title
  
  J Immunol 173(2)
  
  Pages: 1406-1416
- Data Source
  KAKENHI-PROJECT-15590647
[Journal Article] Transforming growth factor a directly augments histidine decarboxylase and vesicular monoamine transporter 2 production in rat enterochromaffin-like cells2004
- Author(s)
  Kazumori H, Ishihara S, et al.
- Journal Title
  
  Am.J.Physiol Gastrointest Liver Physiol 286
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590647
[Journal Article] Effect of prostaglandins on the regulation of tumor2004
- Author(s)
  Ishihara S, et al.
- Journal Title
  
  Curr Med Chem Anti-Canc Agents. 4(4)
  
  Pages: 379-387
- Data Source
  KAKENHI-PROJECT-15590647
[Journal Article] Peroxisome proliferator-activated receptor γ-dependent and- independent growth inhibition of gastrointestinal tumor cells2004
- Author(s)
  Rumi MAK, Ishihara S, et al.
- Journal Title
  
  Genes to Cells 9(11)
  
  Pages: 1113-1123
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590647
[Journal Article] Essential role of MD-2 in TLR4-dependent signaling during Helicobacter pylori-associated gastritis2004
- Author(s)
  Ishihara S, Rumi MAK, et al.
- Journal Title
  
  The Journal of Immunology 173
  
  Pages: 1406-1416
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590647
[Journal Article] Barrett's esophagus with predominant intestinal metaplasia correlates with superficial cyclo-oxygemase-2 expression, increased proliferation and reduced apoptosis : changes that are partially reversed by non-steroidal anti-inflammatory drugs usage2004
- Author(s)
  Amano Y, Ishihara S, et al.
- Journal Title
  
  Aliment Pharm Therapeutics 20(7)
  
  Pages: 793-802
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590647
[Journal Article] Essential role of MD-2 in TLR4-dependent2004
- Author(s)
  Ishihara S, et al.
- Journal Title
  
  The Journal of Immunology 173
  
  Pages: 1406-1416
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590647
[Journal Article] Strategic compartmentalization of tall-like receptor 4 in the mouse gut2003
- Author(s)
  Ortega-Cava CF, Ishihara S, et al.
- Journal Title
  
  The Journal of immunology 170(8)
  
  Pages: 3977-3985
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590647
[Journal Article] MFG-E8 attenuates intestinal inflammation in murine experimental colitis by modulating osteopontin-dependent a_vβ_3-integrin signaling.
- Author(s)
  Aziz MM, Ishihara S, et al
- Journal Title
  
  J Immunol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] 胆管空腸吻合部狭窄に対するBAE-ERCP下治療後無再発期間に関するCOX比例ハザードモデル解析2023
- Author(s)
  尾上　正樹　　福庭　暢彦　　兒玉　康秀　　古谷　聡史　　園山　浩紀　　岡　　明彦　　三島　義之　　大嶋　直樹　　柴垣広太郎　　森山　一郎　　川島　耕作　　石村　典久　　石原　俊治
- Organizer
  第106回日本消化器内視鏡学会総会
- Data Source
  KAKENHI-PROJECT-22K08542
[Presentation] 胃切除後症例における経皮内視鏡的胃瘻・十二指腸瘻造設術の成績2023
- Author(s)
  川島　耕作　　大西　浩二　　尾上　正樹　　岸本　健一　　高橋　佑典　　古谷　聡史　　福庭　暢彦　　大嶋　直樹　　石村　典久　　石原　俊治
- Organizer
  第27回PEG・在宅医療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08542
[Presentation] IPMN術後に残膵癌、多発肝転移をきたした一例2023
- Author(s)
  原　　拓史　　福庭　暢彦　　岸本　健一　　兒玉　康秀　　尾上　正樹　　大嶋　直樹　　川島　耕作　　柴垣広太郎　　石村　典久　　石原　俊治　　古田晃一朗
- Organizer
  第131回日本消化器内視鏡学会中国支部例会
- Data Source
  KAKENHI-PROJECT-22K08542
[Presentation] 胃転移を来したT細胞リンパ腫の2例～内視鏡所見の検討～2023
- Author(s)
  大屋　　聡　　三島　義之　　田中　晋作　　片岡　祐俊　　尾上　正樹　　岡　　明彦　　柴垣広太郎　　大嶋　直樹　　川島　耕作　　石村　典久　　石原　俊治
- Organizer
  第131回日本消化器内視鏡学会中国支部例会
- Data Source
  KAKENHI-PROJECT-22K08542
[Presentation] 難治性潰瘍性大腸炎に対する経口タクロリムス療法のベストユースを再考する―中四国地区多施設共同研究の結果を踏まえて―2023
- Author(s)
  大嶋　直樹　　平岡佐規子　　林　　亮平　　高橋　索真　　石井　　学　　橋本　真一　　八島　一夫　　井川　翔子　　井口　俊博　　上野　義隆　　稲葉　知己　　松本　啓志　　川島　耕作　　高見　太郎　　磯本　　一　　塩谷　昭子　　田中　信治　　石原　俊治
- Organizer
  第20回日本消化管学会総会学術集会
- Data Source
  KAKENHI-PROJECT-22K08542
[Presentation] microRNAを用いた好酸球性食道炎の新規バイオマーカーの探索2022
- Author(s)
  大嶋　直樹　　石村　典久　　石原　俊治
- Organizer
  第108回日本消化器病学会総会(東京）
- Data Source
  KAKENHI-PROJECT-19K08907
[Presentation] microRNAを用いた好酸球性食道炎の新規バイオマーカーの探索2022
- Author(s)
  大嶋　直樹　　石村　典久　　石原　俊治
- Organizer
  第108回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-22K08542
[Presentation] 高齢潰瘍性大腸炎患者に対するタクロリムス投与における腎機能障害の検討2021
- Author(s)
  大嶋　直樹、川島　耕作、石原　俊治
- Organizer
  第107回日本消化器病学会総会、東京
- Data Source
  KAKENHI-PROJECT-18K07971
[Presentation] 実臨床における難治性潰瘍性大腸炎に対するウステキヌマブの治療成績2021
- Author(s)
  川島　耕作　　大嶋　直樹　　岡　　明彦　　三島　義之　　石原　俊治
- Organizer
  第115回日本消化器病学会中国支部例会
- Data Source
  KAKENHI-PROJECT-21K07961
[Presentation] 好酸球性食道炎の治療後経過に関する検討2021
- Author(s)
  石村　典久，沖本　英子，三代　　剛，大嶋　直樹，川島　耕作，石原　俊治
- Organizer
  第17回日本消化管学会総会学術集会
- Data Source
  KAKENHI-PROJECT-19K08907
[Presentation] 高齢潰瘍性大腸炎患者に対するタクロリムス投与における腎機能障害の検討2021
- Author(s)
  大嶋　直樹　　川島　耕作　　石原　俊治
- Organizer
  第107回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-21K07961
[Presentation] 潰瘍性大腸炎の治療目標は組織学的治癒か？－長期臨床的寛解維持予測における内視鏡的完全治癒と組織学的治癒の比較検討－2020
- Author(s)
  岡　　明彦，川島　耕作，園山　浩紀，三島　義之，石原　俊治
- Organizer
  第113回日本消化器病学会中国支部例会
- Data Source
  KAKENHI-PROJECT-17K09383
[Presentation] 潰瘍性大腸炎の治療目標は組織学的治癒か？－長期臨床的寛解維持予測における内視鏡的完全治癒と組織学的治癒の比較検討－2020
- Author(s)
  岡　　明彦、川島　耕作、園山　浩紀、三島　義之、石原　俊治
- Organizer
  第113回日本消化器病学会中国支部例会、山口
- Data Source
  KAKENHI-PROJECT-18K07971
[Presentation] 炎症性腸疾患患者における頭痛・不安・うつ症状の頻度調査：症例対照研究2020
- Author(s)
  福永　真衣，川島　耕作，片岡　祐俊，古谷　聡史，岡　　明彦　，三島　義之，大嶋　直樹，石原　俊治
- Organizer
  第62回日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-17K09383
[Presentation] 感染後過敏性腸症候群におけるTLR9の関与の検討2020
- Author(s)
  三島義之，古谷聡史，川島耕作，石原俊治
- Organizer
  第16回日本消化管学会総会学術集会
- Data Source
  KAKENHI-PROJECT-18K07971
[Presentation] JAK阻害薬トファシチニブによる下肢深部静脈血栓症・肺動脈血栓症を来した潰瘍性大腸炎の1例2020
- Author(s)
  岡　　明彦，川島　耕作，岸本　健一，古谷　聡史，三島　義之，大嶋　直樹，石原　俊治，亀井　史佳，大嶋　丈史，田邊　一明
- Organizer
  第123回日本内科学会中国地方会
- Data Source
  KAKENHI-PROJECT-17K09383
[Presentation] 感染後過敏性腸症候群におけるTLR9の関与の検討2020
- Author(s)
  三島義之，古谷聡史，川島耕作，石原俊治
- Organizer
  第16回日本消化管学会総会学術集会
- Data Source
  KAKENHI-PROJECT-17K09383
[Presentation] Interleukin-33 delays recovery of mucosal inflammation by down-reguation of ABCG5/8 in colon2019
- Author(s)
  Mishima Y, Sonoyama H, Ishihara S, Oshima N, Moriyama I, Kawashima K, Kinoshita Y
- Organizer
  DDW2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07971
[Presentation] 便中カルプロテクチン低値は臨床的内視鏡的寛解潰瘍性大腸炎の組織学的寛解を同定し，長期的な臨床的寛解維持を予測する2019
- Author(s)
  川島耕作，石原俊治，木下芳一
- Organizer
  JDDW2019
- Data Source
  KAKENHI-PROJECT-17K09383
[Presentation] microRNAの網羅的解析を用いた好酸球性食道炎のバイオマーカーの探索2019
- Author(s)
  大嶋直樹、石村典久、石原俊治
- Organizer
  第97回日本消化器内視鏡学会総会
- Data Source
  KAKENHI-PROJECT-19K08907
[Presentation] Interleukin-33 delays recovery of mucosal inflammation by down-reguation of ABCG5/8 in colon2019
- Author(s)
  Mishima Y, Sonoyama H, Ishihara S, Oshima N, Moriyama I, Kawashima K, Kinoshita Y
- Organizer
  DDW2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09383
[Presentation] 潰瘍性大腸炎の病型別にみた粘膜治療評価における各種バイオマーカーの有用性と問題点2019
- Author(s)
  園山浩紀，川島耕作，石原俊治，古谷聡史，三島義之，大嶋直樹，森山一郎，木下芳一
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17K09383
[Presentation] 潰瘍性大腸炎の病型別にみた粘膜治療評価における各種バイオマーカーの有用性と問題点2019
- Author(s)
  Shibagaki K, Yuki T, Taniguchi H, Kotani S, Ishimura N, Ishihara S
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18K07971
[Presentation] 便中カルプロテクチン低値は臨床的内視鏡的寛解潰瘍性大腸炎の組織学的寛解を同定し，長期的な臨床的寛解維持を予測する2019
- Author(s)
  川島耕作，石原俊治，木下芳一
- Organizer
  JDDW2019
- Data Source
  KAKENHI-PROJECT-18K07971
[Presentation] 組織学的所見に基づいた臨床的寛解潰瘍性大腸炎患者における過敏性腸症候群様症状の頻度に関する検討2018
- Author(s)
  川島耕作、石原俊治、福庭暢彦、片岡祐俊、山下詔嗣、園山浩紀、多田育賢、楠龍策、三島義之、大嶋直樹、結城崇史、木下芳一
- Organizer
  。第104回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17K09383
[Presentation] pH依存型メサラジン放出調節製剤投与後に心筋炎を発症した潰瘍性大腸炎の1例.2018
- Author(s)
  川島耕作、石原俊治、加藤輝士、片岡祐俊、古谷聡史、園山浩紀、三島義之、大嶋直樹、木下芳一
- Organizer
  第9回日本炎症性腸疾患学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07971
[Presentation] pH依存型メサラジン放出調節製剤投与後に心筋炎を発症した潰瘍性大腸炎の1例2018
- Author(s)
  川島耕作、石原俊治、加藤輝士、片岡祐俊、古谷聡史、園山浩紀、三島義之、大嶋直樹、木下芳一
- Organizer
  第9回日本炎症性腸疾患学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09383
[Presentation] 組織学的所見に基づいた臨床的寛解潰瘍性大腸炎患者における過敏性腸症候群様症状の頻度に関する検討2018
- Author(s)
  川島耕作、石原俊治、福庭暢彦、片岡祐俊、山下詔嗣、園山浩紀、多田育賢、楠龍策、三島義之、大嶋直樹、結城崇史、木下芳一
- Organizer
  第104回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18K07971
[Presentation] Epidermaldifferentiation complex protein involucrin is down-regukated in eosinophikic esophagitis2016
- Author(s)
  Oshima N, Ishihara S, Fukuba N, Kawashima K, Ishimura N, Kinoshita Y
- Organizer
  Asian pacific Digestive Week 2016
- Place of Presentation
  Kobe Convention Center, Hyogo, Japan
- Year and Date
  2016-11-02
- Data Source
  KAKENHI-PROJECT-26460970
[Presentation] Presistent decrease in colonic regulatory CD5+ B cell pissibly associated with pathogenesis of inflammatory bowel disease2016
- Author(s)
  Mishima Y, Ishihara S, Oka A, Fukuba N, Oshima N, Sonoyama H, Yamashita N, Tada Y, kusunoki R, Moriyama I, yuki T, Kawashima K, Kinoshita Y
- Organizer
  The 4th Annual Meeting of Asian Organization for Crohn's & Colitis
- Place of Presentation
  Kyoto International Conference Center, Kyoto, Japan
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-26460970
[Presentation] Psychological state of subjects with irritable bowel syndrome and headache: annual health check-up survey results2015
- Author(s)
  Kawashima K, Ishihara S, Uemura Y, Kazumori H, Katsube T, Sonoyama H, Tada Y, Kusunoki R, Oka A, Fukuba N, Oshima N, Yuki T, Kinoshita Y
- Organizer
  Digestive Disease Week 2015
- Place of Presentation
  Washington, USA
- Year and Date
  2015-05-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460970
[Presentation] Apoptotic neutrophils ameliorate intestinal inflammation2015
- Author(s)
  Ishihara S, Kawashima K, Sonoyama H, Tada Y, Oka A, Kusunoki R, Fukuna N, Oshima N, Moriyama I, Yuki T, Maegawa H, Kashiwagi N, Kinoshita Y
- Organizer
  10th Congress of European European Crohn's Colitis Organisation（ECCO）
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2015-02-20
- Data Source
  KAKENHI-PROJECT-26460970
[Presentation] Serum amyloid A level correlated with endoscopic findings in patients with Crohn's disease-possible biomarker for evaluating mucosal healing2015
- Author(s)
  Tada Y, Ishihara S, Sonoyama H, Oka A, Fukuba N, Oshima N, Moriyama I, Yuki T, Kawashima K, Kinoshita Y
- Organizer
  10th Congress of European European Crohn's Colitis Organisation（ECCO）
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2015-02-20
- Data Source
  KAKENHI-PROJECT-26460970
[Presentation] Matrix Metalloproteinase-3 Concentration Correlates with Clinical and Endoscopic Evidence of Ulcerative Colitis2015
- Author(s)
  Kawashima K, Ishihara S, Sonoyama H, Tada Y, Oka A, Kusunoki R, Fukuba N, Oshima N, Moriyama I, Yuki T, Kinoshita Y
- Organizer
  10th Congress of European European Crohn's Colitis Organisation（ECCO）
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2015-02-20
- Data Source
  KAKENHI-PROJECT-26460970
[Presentation] 腸管炎症におけるIL-33の役割2015
- Author(s)
  園山　浩紀、大嶋　直樹、石原　俊治、山下　詔嗣、多田　育賢、岡　　明彦、福庭　暢彦、森山　一郎、結城　崇史、川島　耕作、木下　芳一
- Organizer
  第11回日本消化管学会総会学術集会
- Place of Presentation
  京王プラザホテル（東京）
- Year and Date
  2015-02-13
- Data Source
  KAKENHI-PROJECT-26460970
[Presentation] Fecal calprotectin concentration correlated with both endoscopic severity and disease extent in ulcerative colitis: Analysis of sum of Mayo endoscopic subscore for five colon segments2015
- Author(s)
  Kawashima K, Ishihara S, Yuki T, Sonoyama H, Tada Y, Oka A, Kusunoki R, Fukuba N, Oshima N, Moriyama I, Kinoshita Y
- Organizer
  Digestive Disease Week 2015
- Place of Presentation
  Washington, USA
- Year and Date
  2015-05-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460970
[Presentation] ワークショップ：腸疾患病態研究の進歩－免疫と腸内環境－；制御性B細胞による腸管免疫の機能維持とその破綻による腸炎発症機序の検討2014
- Author(s)
  岡　　明彦、石原　俊治、木下　芳一
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京国際フォーラム（東京）
- Year and Date
  2014-04-26
- Data Source
  KAKENHI-PROJECT-26460970
[Presentation] Research Forum：炎症性腸疾患の病態と診断2014
- Author(s)
  川島　耕作、石原　俊治　　結城　崇史、園山　浩紀、多田　育賢、岡　　明彦、楠　　龍策、福庭　暢彦、大嶋　直樹、木下　芳一
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京国際フォーラム（東京）
- Year and Date
  2014-04-23
- Data Source
  KAKENHI-PROJECT-26460970
[Presentation] Eelevated matrix metalloproteinase-3 Levels in serum correlated with Crohn's disease severity: efficacy as clinical biomarker2013
- Author(s)
  Kawashima K, Ishihara S, Sonoyama H, Tada Y, Oka A, Kusunoki R, Fukuba N, Oshima N, Moriyama I, Yuki T, Kinoshita Y
- Organizer
  United European Gastroenterology Week (UEGW)
- Place of Presentation
  Berlin (International Congress Centrum (ICC Berlin)), Germany
- Year and Date
  2013-10-15
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] Susceptibility for colitis-associated cancer development in SAMP1/Yit mice2013
- Author(s)
  Ishihara S Tada Y, Fukuba N, Sonoyama H, Oka A, Kusunoki R, Oshima N, Moriyama I, Yuki T, Kawashima K, Kushiyama Y, Fujishiro H, Kinoshita Y
- Organizer
  United European Gastroenterology Week (UEGW)
- Place of Presentation
  Berlin (International Congress Centrum (ICC Berlin)), Germany
- Year and Date
  2013-10-16
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] Down-regulation of serotonin reuptake transporter gene expression in colonic mucosa during inflammation and healing phases of inflammatory bowel disease2012
- Author(s)
  Tada Y, Ishihara S, Kinoshita Y
- Organizer
  United European Gastroenterology Week (UEGW)
- Place of Presentation
  Amsterdam (Amsterdam RAI), Netherlands
- Year and Date
  2012-10-23
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] Regulatory role of CD19highCD1dhigh B cells in intestinal inflammation: association with pathogenesis of Crohn's disease2012
- Author(s)
  Oka A, Ishihara S, Sonoyama H, Tada Y, A.U. Mesbah, Fukuba N, Moriyama I, Yuki T, Kawashima K, Kinoshita Y
- Organizer
  United European Gastroenterology Week (UEGW)
- Place of Presentation
  Amsterdam (Amsterdam RAI), Netherlands
- Year and Date
  2012-10-22
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] Effects of pH-dependent release formulation of mesalazine on active ulcerative colitis resistant to time-dependent release formulation of mesalazine2012
- Author(s)
  Kawashima K, Ishihara S, Oka A, Fukuba N, Ryusaku K, Tada Y, Tamagawa Y, Yuki T, Moriyama I, Yuki T, Kinoshita Y
- Organizer
  United European Gastroenterology Week (UEGW)
- Place of Presentation
  Amsterdam (Amsterdam RAI), Netherlands
- Year and Date
  2012-10-23
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] クローン病モデルマウスのＴ細胞に対する制御性Ｂ細胞の影響2011
- Author(s)
  ○岡明彦、石原俊治、多田育賢、楠龍策、福庭暢彦、森山一郎、結城崇史、天野祐二、木下芳一
- Organizer
  第53回日本消化器病学会大会
- Place of Presentation
  福岡国際センター他（福岡市）
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] ノックアウトマウスを用いたMFG-E8の腸管炎症制御の機能解析と治療への応用2011
- Author(s)
  楠龍策, 石原俊治, 結城崇史, 木下芳一
- Organizer
  第7回消化管学会総会学術集会
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] ノックアウトマウスを用いたMFG-E8の腸管炎症制御の機能解析と治療への応用2011
- Author(s)
  楠龍策, 石原俊治, 他
- Organizer
  第7回消化管学会総会学術集会
- Place of Presentation
  福岡
- Year and Date
  2011-02-18
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] 制御性Ｂ細胞による腸管免疫抑制機構とその破綻による腸炎発症機序の解明-クローン病モデルマウスの病態解析からの知見とその応用-2011
- Author(s)
  ○岡明彦、石原俊治、木下芳一
- Organizer
  第53回日本消化器病学会大会:シンポジウム"消化器疾患と免疫"
- Place of Presentation
  福岡国際センター他（福岡市）
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] Intestinal inflammation down-regulates SIGIRR/TIR8 expression in epithelial cells by inhibiting SP1-mediated pathway2010
- Author(s)
  Kadota C, Ishihara S, et al
- Organizer
  Digestive Disease Week
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] Decreased production of IL-10 in TLR9-activated peripheral blood B cells in inflammatory bowel disease2010
- Author(s)
  Oka A, Ishihara S, et al
- Organizer
  Digestive Disease Week
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] Crosstalk between TLR5 and Notch1 signaling in epithelial cells during intestinal inflammation.2010
- Author(s)
  Yuki T, Ishihara S, Aziz MM, Mishima Y, Oshima N, Otani A, Oka A, Kusunoki R, Tada Y, Moriyama I, Yoshikazu K
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] 腸管炎症におけるNotch-1とTLR5シグナルの相互作用に関する検討2010
- Author(s)
  結城崇史, 石原俊治, 他
- Organizer
  第96回日本消化器病学会総会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] Chron病モデルマウスの病態における腸管B細胞の機能異常に関する検討2010
- Author(s)
  岡明彦, 石原俊治, 三島義之, 多田育賢, 楠龍策, 大谷文, 森山一郎, 結城崇史, 天野祐二, 木下芳一
- Organizer
  第52回日本消化器病学会大会
- Place of Presentation
  横浜
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] 炎症性腸疾患患者の末梢血B細胞におけるIL-10産生能に関する検討2010
- Author(s)
  岡明彦, 石原俊治, 三島義之, 多田育賢, 楠龍策, 大谷文, 森山一郎, 結城崇史, 天野祐二, 木下芳一
- Organizer
  第96回日本消化器病学会総会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] Intestinal inflammation down-regulates SIGIRR/TIR8 expression in epithelial cells by inhibiting SP1-mediated pathway.2010
- Author(s)
  Kadota C, Ishihara S, Mishima Y, Oshima N, Oka A, Kusunoki R, Tada Y, Moriyama I, Yuki T, Kinoshita Y
- Organizer
  Digestive Disease Week.
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] 炎症性腸疾患の腸管粘膜局所におけるMFG-E8の発現に関する検討2010
- Author(s)
  多田育賢, 石原俊治, 楠龍策, 大谷文, 三島義之, 大嶋直樹, 森山一郎, 結城崇史, 天野祐二, 木下芳一
- Organizer
  第52回日本消化器病学会大会
- Place of Presentation
  横浜
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] 腸管炎症におけるNotch-1とTLR5シグナルの相互作用に関する検討。2010
- Author(s)
  結城崇史, 石原俊治, 多田育賢, 楠龍策, 大谷文, 三島義之, 天野祐二, 木下芳一
- Organizer
  第96回日本消化器病学会総会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] Crosstalk between TLR5 and Notch1 signaling in epithelial cells during intestinal inflammation2010
- Author(s)
  Yuki T, Ishihara S, et al
- Organizer
  Digestive Disease Week
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] Decreased production of IL-10 in TLR9-activated peripheral blood B cells in inflammatory bowel disease.2010
- Author(s)
  Oka A, Ishihara S, Mishima Y, Oshima N, Kusunoki R, Tada Y, Moriyama I, Yuki T, Kinoshita Y
- Organizer
  Digestive Disease Week.
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] 炎症性腸疾患の末梢血CD5陽性B細胞の解析2009
- Author(s)
  三島義之, 石原俊治, 大谷文, 天野祐二, 木下芳一
- Organizer
  第5回日本消化管学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] 精製MFG-E8蛋白の経肛門的投与による実験腸炎抑制の試み2009
- Author(s)
  大谷文、石原俊治, 大嶋直樹、三島義之、岡明彦、楠龍策、森山一郎、天野祐二、木下芳一
- Organizer
  第95回日本消化器病学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] Intrarectal administration of MFG-E8 protein ameliorates murine experimental colitis by inhibiting NF-κB activation in intestinal epithelial cells.2009
- Author(s)
  Oshima N, Ishihara S, Kadota C, Oka A, Kusunoki R, Moriyama I, AmanoY, Kinoshita Y
- Organizer
  Digestive Disease Week 2009
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] クローン病モデルマウスにおけるIL-10産生腸管制御性B細胞に関する検討2009
- Author(s)
  三島義之, 石原俊治, 木下芳一
- Organizer
  第51回日本消化器病学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] Crosstalk between Notch and toll signaling in murine colitis.2009
- Author(s)
  Ishihara S, Aziz M, Mishima Y, Oshima N, Otani A, Oka A, Kusunoki R, Moriyama I, Ishimura M, Li YY, Amano Y, Kinoshita Y
- Organizer
  Digestive Disease Week 2009
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] Decreased production of IL-10 and TGF-β in TLR-activated intestinal B cells in SAMP1/Yit mice.2009
- Author(s)
  Mishima Y, Ishihara S, Aziz M, Oshima N, Otani A, Oka A, Kusunoki R, Moriyama I, Amano Y, Kinoshita Y
- Organizer
  Digestive Disease Week 2009
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] クローン病モデルマウスにおけるIL-10産生B細胞に関する検討2009
- Author(s)
  三島義之, 石原俊治, 楠龍策、岡明彦, 大谷文, 大嶋直樹, 森山一郎, 天野祐二, 木下芳一
- Organizer
  第95回日本消化器病学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] Intestinal CD5^+ B cells produce IL-10 and TGF-β via Toll-like receptor-mediated signaling.2008
- Author(s)
  Mishima Y, Ishihara S, Aziz MM, Rumi MAK, Oshima N, Kadota C, Moriyama I, Li YY, Ohtani A, Oka A, Kadowaki Y, Amano Y, Kinoshita Y
- Organizer
  Digestive Disease Week 2008
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] Milk fat globule EGF-8 attenuates intestinal inflammation in murine experimental colitis via inhibition of NF-κB activation.2008
- Author(s)
  Ishihara S, Aziz M, Rumi MA, Oshima N, Mishima Y, Kadota C, Otani A, Oka A, Norihisa I, Moriyama I, Kadowaki Y, Amano Y, Kinoshita Y
- Organizer
  Digestive Disease Week 2008
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] 下部消化管の炎症と機能相関をめぐって消化管上皮の自然免疫応答におけるA20発現の意義2008
- Author(s)
  大嶋直樹, 石原俊治, 木下芳一, パネルディスカッション
- Organizer
  第50回日本消化器病学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] 消化管粘膜におけるIL-10、TGF-beta産生B細胞に関する検討2008
- Author(s)
  三島義之, 石原俊治, 岡明彦, 大谷文, 大嶋直樹, 角田力, 森山一郎, 天野祐二, 木下芳一
- Organizer
  第50回日本消化器病学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] A20 is an early responsive negative regulator of Toll-like receptor signaling in intestinal epithelial cells during inflammation.2008
- Author(s)
  Oshima N, Ishihara S, Rumi MAK, Aziz MM, Mishima Yo, Kadota C, Moriyama I, Ohtani A, Oka A, Li YY, Kadowaki Y, AmanoY, Kinoshita Y
- Organizer
  Digestive Disease Week 2008
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-20590723
[Presentation] 活動期潰瘍性大腸炎に対するpH依存性メサラジン製剤の治療効果
- Author(s)
  川島耕作，石原俊治，結城崇史，他
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル（東京都）
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] Susceptibility for colitis-associated cancer development in SAMP1/Yit mice
- Author(s)
  Ishihara S Tada Y, Fukuba N, Sonoyama H, Oka A, Kusunoki R, Oshima N, Moriyama I, Yuki T, Kawashima K, Kushiyama Y, Fujishiro H, Kinoshita Y
- Organizer
  United European Gastroenterology Week (UEGW)
- Place of Presentation
  Messe Berlin (Berlin, Germany)
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] Regulatory role of CD19highCD1dhigh B cells in intestinal inflammation: association with pathogenesis of Crohn’s disease
- Author(s)
  Oka A, Ishihara S, Sonoyama H, et al
- Organizer
  United European Gastroenterology Week (UEGW)
- Place of Presentation
  Amsterdam, The Netherlands
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] Televated matrix metalloproteinase-3 Levels in serum correlated with Crohn’s disease severity: efficacy as clinical biomarker
- Author(s)
  Kawashima K, Ishihara S, Sonoyama H, Tada Y, Oka A, Kusunoki R, Fukuba N, Oshima N, Moriyama I, Yuki T, Kinoshita Y
- Organizer
  United European Gastroenterology Week (UEGW)
- Place of Presentation
  Messe Berlin (Berlin, Germany)
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] Down-regulation of serotonin reuptake transporter gene expression in colonic mucosa during inflammation and healing phases of inflammatory bowel disease
- Author(s)
  Tada Y, Ishihara S, Kinoshita Y
- Organizer
  United European Gastroenterology Week (UEGW)
- Place of Presentation
  Amsterdam, The Netherlands
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] Elevated serum pancreatic enzymes in inflammatory bowel disease associated with clinical parameters
- Author(s)
  Sonoyama H, Kawashima K, Ishihara S, Tada Y, Oka A, Kusunoki R, Fukuba N, Oshima N, Moriyama I, Yuki T, Kinoshita Y
- Organizer
  The 1 st Annual Meeting of Asian Organization for Crohn’s & Colitis
- Place of Presentation
  Hotel Laforet Tokyo（Tokyo, Japan）
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] MFG-E8の大腸炎症および発癌への関与
- Author(s)
  楠　龍策，石原俊治，多田育賢，他
- Organizer
  第54回日本消化器病学会大会
- Place of Presentation
  神戸国際展示場（神戸市）
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] 寛解期潰瘍性大腸炎患者IBS様症状と内視鏡像についての多施設共同研究
- Author(s)
  福庭暢彦，石原俊治，多田育賢，他
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル（東京都）
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] 潰瘍性大腸炎患者における血清マトリックスメタロプロテイナーゼ-3の疾患活動性マーカーとしての有用性の検討
- Author(s)
  川島耕作，石原俊治，園山浩紀，多田育賢，岡　明彦，楠　龍策，福庭暢彦，大嶋直樹，結城崇史，木下芳一
- Organizer
  第21回日本消化器関連学会週間　JDD 2013
- Place of Presentation
  ｸﾞﾗﾝﾄﾞプリンスホテル新高輪（東京）
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] シンポジウム14　腸管炎症におけるserotonin reuptake transporterの遺伝子発現と機能性消化管障害の病態への関与
- Author(s)
  多田育賢，石原俊治，木下芳一
- Organizer
  54回日本消化器病学会大会
- Place of Presentation
  神戸国際展示場（神戸市）
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] Role of milk fat globule-epidermal growth factor 8 in intestinal inflammation and carcinogenesis
- Author(s)
  Kusunoki R, Ishihara S, Sonoyama H, et al
- Organizer
  United European Gastroenterology Week (UEGW)
- Place of Presentation
  Amsterdam, The Netherlands
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] Role of milk fat globule-epidermal growth factor 8 during Citrobacter rodentium-induced colitis in mice
- Author(s)
  Oshima N, Ishihara S, Sonoyama H, Tada Y, Oka A, Kusunoki R, Fukuba N, Moriyama I, Yuki T, Kawashima K, Ansary MM, Kinoshita Y
- Organizer
  United European Gastroenterology Week (UEGW)
- Place of Presentation
  Messe Berlin (Berlin, Germany)
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] 難治性潰瘍性大腸炎に対するタクロリムスによる寛解導入治療症例の経過
- Author(s)
  結城崇史，石原俊治，多田育賢，他
- Organizer
  第54回日本消化器病学会大会
- Place of Presentation
  神戸国際展示場（神戸市）
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] Expression profiles of angiogenesis- and inflammation-related genes in colonic mucosa of ulcerative colitis in remission - comparison with narrow-band imaging magnifying colonoscopy findings
- Author(s)
  Yuki T, Ishihara S, Sonoyama H, et al
- Organizer
  United European Gastroenterology Week (UEGW)
- Place of Presentation
  Amsterdam, The Netherlands
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] Effects of pH-dependent release formulation of mesalazine on active ulcerative colitis resistant to time-dependent release formulation of mesalazine.
- Author(s)
  Kawashima K, Ishihara S, Oka A, et al
- Organizer
  United European Gastroenterology Week (UEGW)
- Place of Presentation
  Amsterdam, The Netherlands
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] 制御性B細胞による腸炎抑制効果　制御生T細胞非依存的な抑制機構の検討
- Author(s)
  岡　明彦，石原俊治，多田育賢，他
- Organizer
  第54回日本消化器病学会大会
- Place of Presentation
  神戸国際展示場（神戸市）
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] Prevalence of irritable bowel syndrome-like symptoms in ulcerative colitis patients with clinical and endoscopic evidence of remission: prospective multicenter study
- Author(s)
  Fukuba N, Ishihara S Tada Y, Sonoyama H, Oka A, Kusunoki R, Oshima N, Moriyama I, Yuki T, Kawashima K, Kushiyama Y, Fujishiro H, Kinoshita Y
- Organizer
  United European Gastroenterology Week (UEGW)
- Place of Presentation
  Messe Berlin (Berlin, Germany)
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] 炎症性腸疾患の膵酵素異常についての臨床的検討
- Author(s)
  園山浩紀，川島耕作，石原俊治，多田育賢，岡　明彦，楠　龍策，福庭暢彦，大嶋直樹，森山一郎，結城崇史，木下芳一
- Organizer
  第21回日本消化器関連学会週間（JDD 2013）
- Place of Presentation
  ｸﾞﾗﾝﾄﾞプリンスホテル新高輪（東京）
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] 緩解期潰瘍性大腸炎粘膜におけるNBI拡大所見と局所炎症所見および血管新生因子の対比
- Author(s)
  結城崇史，石原俊治，多田育賢，他
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル（東京都）
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] Milk fat globule-epidermal growth factor 8 accelerates angiogenesis-related gene expression in colonic mucosa during regenerating phase of colitis
- Author(s)
  Tada Y, Ishihara S, Kusunoki R, Fukuba N, Sonoyama H, Oka A, Moriyama I, Yuki T, Kawashima K, Ansary MM, Kinoshita Y
- Organizer
  United European Gastroenterology Week (UEGW)
- Place of Presentation
  Messe Berlin (Berlin, Germany)
- Data Source
  KAKENHI-PROJECT-23590942
[Presentation] 潰瘍性大腸炎の大腸粘膜におけるセロトニン取り込みトランスポーターの発現に関する検討
- Author(s)
  多田育賢，石原俊治，楠　龍策，他
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル（東京都）
- Data Source
  KAKENHI-PROJECT-23590942

1. OSHIMA Naoki (10403461)

# of Collaborated Projects: 4 results

# of Collaborated Products: 17 results
2. KAZUMORI Hideaki (20332786)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 三島義之 (30397864)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
4. 岡明彦 (80600600)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. YOSHIKAZU Kinoshita (30243306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. AMANO Yuji (80284032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ISHIMURA Norihisa (40346383)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. kawashima Kousaku (10609267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
9. Niibayashi Tomomi (50529675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Yamamoto Tatsuyuki (60230570)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 足立経一 (50192969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 福田亮 (50208972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. モハマドルミ (00379687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 臼田春樹 (30707667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 和田孝一郎 (90263467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 佐藤英俊 (10300873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. SUZUKI Hiromu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. NAKASE Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. NOOTHALAPATI Hemanth

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 渡辺守

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 松本健次郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ISHIHARA Shunji 石原 俊治

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A study regarding a novel anti-inflammatory eosinophil subset on pathogenesis of eosiophilic gastroenteritisPrincipal Investigator

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Analysis of B cell functions regulating intestinal mucosal permeability on the pathogenesis of Crohn's diseasePrincipal Investigator

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Elucidation of a novel mechanism leading regulatory B cells dysfunction of in Crohn's diseasePrincipal Investigator

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Elucidation of the molecular mechanism of induction/activation of regulatory B cells and its application to regulation of intestinal inflammationPrincipal Investigator

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Role of regulatory B cells in chronic intestinal inflammation: association with pathogenesis of Crohn's diseasePrincipal Investigator

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Investigation regarding the role of MFG-E8 on NF-κB-dependent intestinal inflammation : Development of a new anti-inflammatory targeting MFG-E8Principal Investigator

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ISHIHARA Shunji 石原俊治