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TAUCHI Tetsuzo  田内 哲三

ORCIDConnect your ORCID iD *help
Researcher Number 80281377
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2009: 東京医大, 医学部, 准教授
2008: Tokyo Medical University, 医学部, 准教授
2001 – 2007: 東京医科大学, 医学部, 講師
1996 – 2000: 東京医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Hematology / Hematology
Keywords
Principal Investigator
BCR-ABL / G-quadruplex / 慢性骨髄性白血病 / アポトーシス / テロメラーゼ / テロメア / Targeted Therapy / Apoptosis / Telomerace / siRNA … More / 分子標的治療 / p38MAP Kinase / DNA damage / テロメスタチン / 優勢変異型hTERT / 分子標的療法 / テロメクーゼ / 分子標的遺伝 / cell cycle / apoptosis / telomerace / felomese / hTERT / 細胞同期 / G-guadruplex / 細胞周期 / Srcキナーゼ / Dasatinib / Auroraキナーゼ / DNA修復 / 耐性化 / CIS1 / 慢性骨髄性白血症 / 病態の分子機構 / 性能ドメイン / 機能ドメイン / シグナル伝達 Less
  • Research Projects

    (6 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (3 People)
  •  慢性骨髄性白血病におけるDNA修復エラーの分子病態と微少残存病変の制御の研究Principal Investigator

    • Principal Investigator
      田内 哲三
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Tokyo Medical University
  •  Holocular Targeted Therapy in hemabrogical neoplasm: Telomerase InhibitionPrincipal Investigator

    • Principal Investigator
      TAUCHI Tetsuzo
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Tokyo Medical University
  •  Development of molcular target therapy for.... telomerasePrincipal Investigator

    • Principal Investigator
      TAUCHI Tetsuzo
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Tokyo Medical University
  •  CIS1ノックアウトマウスを用いた慢性骨髄性白血病の病態の分子機構の解析Principal Investigator

    • Principal Investigator
      田内 哲三
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Hematology
    • Research Institution
      Tokyo Medical University
  •  BCR-ABL変異体を用いた慢性骨髄性白血病の病態の分子機構の解析Principal Investigator

    • Principal Investigator
      田内 哲三
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Hematology
    • Research Institution
      Tokyo Medical University
  •  BCR-ABL変異体を用いた機能ドメインの解析と細胞内分子との相互作用の研究Principal Investigator

    • Principal Investigator
      田内 哲三
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Hematology
    • Research Institution
      Tokyo Medical University

All 2008 2007 2006 2005 2004

All Journal Article Presentation

  • [Journal Article] Sustained complete cytogenetic remission in a patient with CHL after discontinuator of imatinib methylate2007

    • Author(s)
      Okebe S, Tauchi; T, et al.
    • Journal Title

      Int J Hematol 85-2

      Pages: 173-174

    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] Sustained complete cytogenetic remission in a patient with chronic myeloid leukemia after discontinuation of imatinib mesylate therapy.2007

    • Author(s)
      Okabe S, Tauchi T, et al.
    • Journal Title

      Int J Hematol. 85(2)

      Pages: 173-174

    • NAID

      10018553294

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] Identification and functional signiture of geros regulator by structurally signiture the ABL-〓2007

    • Author(s)
      Nonoda K, Tauchi T, et. al.
    • Journal Title

      Oncegene 26

      Pages: 4179-4188

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591140
  • [Journal Article] Rocurrent chromoso〓 abberation of 12〓15 in chronil idiop〓hic my〓fih〓 with 〓 Jeak 〓2007

    • Author(s)
      Ohyashiki K, Tauchi T, et. al.
    • Journal Title

      Levkema 21

      Pages: 1578-1580

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591140
  • [Journal Article] Identification and functional signature of genes regulated by structurally different ABL kinase inhibitors.2007

    • Author(s)
      Nunoda K, Tauchi T, et al.
    • Journal Title

      Oncogene. (Epub ahead of print)

      Pages: 8-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] Identification and functional signature of genes regulated by structoraly different ABL kinase inhibitors.2007

    • Author(s)
      Nunoda K, Tauchi T, et al.
    • Journal Title

      Oncogene (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] Identification and functional signature of genes regulated by structurally different ABL kinase inhibitor2007

    • Author(s)
      Nunoea k, Tauchi: T et al.
    • Journal Title

      Oncogene in press

    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] The second generation of BCR-ABL tycosine kinase inhibitors2006

    • Author(s)
      Tauchi T, Chyashiki K
    • Journal Title

      Int J Hematols 83・4

      Pages: 294-300

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] Stronnal-cell-derived factor-1/CXCL12-induced chemotasins of a T cell line involues intracellular signaling through Cbl and CS1-62006

    • Author(s)
      Okabe S, Tauchi T, et al.
    • Journal Title

      Blood Cells Mol Dis 36・2

      Pages: 308-314

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] Stromal-cell-derived factor-1/CXCL12-induced chemotaxis of a T cell line involves intracellular cignelity through Cbl and Cbl-b2006

    • Author(s)
      Okebe S, Tauchi; T, et al.
    • Journal Title

      Blood Cells Mol Dis 36-2

      Pages: 308-314

    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] Telomerase inhibition with a novel G-guadaptor-interacting agent, telomestatin : in vitro and in vivo studies in acute leukemia2006

    • Author(s)
      Tauchi; T, Shin-ya k, et al.
    • Journal Title

      Oncogene 25-42

      Pages: 5719-5724

    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] Stromal-cell-derived factor-1/CXCL12-induced chemotaxis of a T cell line involves intracellular signaling through Cbl and Cbl-b.2006

    • Author(s)
      Okabe S, Tauchi T, et al.
    • Journal Title

      Blood Cells Mol Dis (in press)

    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin : in vitro and in vivo studies in acute leukemia.2006

    • Author(s)
      Tauchi T, Shin-ya K, et al.
    • Journal Title

      Oncogene. 25(42)

      Pages: 5719-5725

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] The second generation of BCR-ABL tyrosine kinase inhibitors.2006

    • Author(s)
      Tauchi T, Ohyashiki K
    • Journal Title

      Int J Hematol. 83(4)

      Pages: 294-300

    • NAID

      10017475375

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] Telomerase inhibition with a novel G-guadroples-interacting agent,telomestatin : in vitro and in vivo studies in acute leucemia2006

    • Author(s)
      Tauchi T, Shin-ya K, et al.
    • Journal Title

      Oncogene 25・42

      Pages: 5719-5725

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] The second generation of BCR-ABL tyrosine kinase inhibitor2006

    • Author(s)
      Tauchi: T, Ohyashik:k.
    • Journal Title

      Int J Hematol 83-4

      Pages: 294-300

    • NAID

      10017475375

    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin : in vitro and in vivo studies in acute leukemia2006

    • Author(s)
      Tauchi T, Shin-ya K, et al.
    • Journal Title

      Oncogene (in press)

    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] Stromal-cell-derived factor-1/CXCL12-induced chemotaxis of a T cell line involves intracellular signaling through Cbl and Cbl-b and their regulation by Src kinases and CD45.2006

    • Author(s)
      Okabe S, Tauchi T, et al.
    • Journal Title

      Blood Cells Mol Dis. 36(2)

      Pages: 308-314

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] Successful treatment with interferon-alpha in a case of acute myeloid leukemia with del(20q) following polycythemia vera.2005

    • Author(s)
      Sumi M, Tauchi T, et al.
    • Journal Title

      Rinsho Ketsueki 46 : 11

      Pages: 1208-1212

    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] Marked telomere fluctuation of leukocytes during graft-versus-host disease in allogeneic stem cell transplantation.2005

    • Author(s)
      Sashida G, Tauchi T, et al.
    • Journal Title

      Int J Mol Med 16 : 5

      Pages: 883-888

    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] Clinical usefulness of transcription-mediated amplification and hybridization protection assay in imatinib-treated chronic myelogenous leukemia patients2005

    • Author(s)
      Sumi M, Tauchi T, et al.
    • Journal Title

      Clin Lab Haematol 27 : 6

      Pages: 416-417

    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] A G-quadruplex-interactive agent, telomestatin, induces telomere shortening with apoptosis and enhances chemosensitivity in acute leukemia2004

    • Author(s)
      Sumi M, Tauchi T, Sashida G et al.
    • Journal Title

      International Journal of Oncology 24-6

      Pages: 1481-1487

    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] Imatinib mesylate in combination with other chemotherapeutic agents for chronic myelogenous leukemia2004

    • Author(s)
      Tauchi T, Ohyashiki K
    • Journal Title

      International Journal of Hematology 79・5

      Pages: 434-440

    • NAID

      10013149008

    • Data Source
      KAKENHI-PROJECT-16590965
  • [Journal Article] Molecular mechanisms of resistance of leukemia to imatinib2004

    • Author(s)
      Tauchi T, Ohyashiki K
    • Journal Title

      Leukemia Research 28 Suppl

    • Data Source
      KAKENHI-PROJECT-16590965
  • [Presentation] Combined effects of novel heat shock protein 90 inhibitor NVP-AUY922 and nilotinib against mutant forms of BCR-ABL.2008

    • Author(s)
      Tauchi T
    • Organizer
      50^<th> Annual Meeting of American Society of Hematology
    • Place of Presentation
      サンフランシスコ
    • Year and Date
      2008-12-08
    • Data Source
      KAKENHI-PROJECT-19591140
  • 1.  黒田 雅彦 (80251304)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  嶋本 隆司 (60317865)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  垣見 和宏 (80273358)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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