Sakai Hiroyuki 酒井博幸

… Alternative Names

SAKAI Hiroyuki 酒井博幸

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Researcher Number	80281731
Other IDs
Affiliation (Current)	2022: 京都大学, 医生物学研究所, 准教授
Affiliation (based on the past Project Information) *help	2011 – 2013: 京都大学, ウイルス研究所, 准教授 1996 – 2004: 京都大学, ウイルス研究所, 助教授
Review Section/Research Field	Principal Investigator Biological Sciences / Virology / Virology Except Principal Investigator Virology
Keywords	Principal Investigator HPV / パピローマウイルス / ウイルス発がん / 子宮頚癌 / 転写因子 / テロメレース / 細胞周期 / 子宮頸癌 / ウイルス複製 / tumor virus … More / 細胞分化 / E2 / エイズ / HIV-1 / env / 蛋白質機能 / TM / テロメラーゼ / 腫瘍形成 / 抗ウイルス剤 / human papillomavirus / 重層上皮形成 / papillomavirus / cervical cancer / viral replication / ケラチノサイト / 皮膚モデル培養系 / 転写 / DNA複製 / keratinocyte / differentation / organotypic culture / transcription / DNA replication / がんウイルス / 過形成 / がん遺伝子 / 上皮組織 / 癌抑制遺伝子 / virus replication / viral oncology / hyperplasia … More Except Principal Investigator マウス白血病ウイルス / レトロウイルス / 抵抗性遺伝子 / Fv‐4 / 遺伝子治療 / マウス免疫不全ウイルス / Fv-4 / MAIDS / マウスレトロウイルス / 白血病ウイルス / フレンドウイルス / Fr-4 / ヌードマウス / Retroviurs / Murine Retrovirus / Resistant gene / FK506 / 日和見発癌 / 日和見感染 / opportunistic cancer / Retrovirus / Murine Leukemia Virus / Murine AIDS virus Less

Understandings of the HPV-induced tumorigenesis for developing anti-virus reagents.Principal Investigator
- Principal Investigator
  
  SAKAI Hiroyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kyoto University
Analysis of HPV regulatory gene function with organotypic culture of epithelial cells.Principal Investigator
- Principal Investigator
  
  SAKAI Hiroyuki
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
皮膚三次元培養モデルにおけるヒトパピローマウイルス複製機構の解析Principal Investigator
- Principal Investigator
  
  酒井博幸
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Functional analysis of HPV genes in keratinocyte organotypic culture system.Principal Investigator
- Principal Investigator
  
  SAKAI Hiroyuki
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
Studies on opportunistic oncogenesis in immunodeficient mouse by murine retroviruses.
- Principal Investigator
  
  ISHIMOTO Akinori
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  KYOTO UNIVERSITY
ケラチノサイト三次元培養系を用いたヒトパピローマウイルス遺伝子機能の解析Principal Investigator
- Principal Investigator
  
  酒井博幸
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
Functional interaction between gene expression and DNA replication of HPV lifecylePrincipal Investigator
- Principal Investigator
  
  SAKAI Hiroyuki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  KYOTO UNIVERSITY
HPV16E2蛋白の子宮頸癌細胞増殖阻害の分子機構の解明とその応用に向けての研究Principal Investigator
- Principal Investigator
  
  酒井博幸
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
HIVのTM蛋白質サイトプラスミック・ドメインの細胞特異的機能に関する研究Principal Investigator
- Principal Investigator
  
  酒井博幸
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Analysis of Fv-4 gene resistant to retrovirus infection
- Principal Investigator
  
  ISHIMOTO Akinori
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  KYOTO UNIVERSITY
レトロウイルス感染に抵抗性遺伝子Fv‐4の作用機構の解析
- Principal Investigator
  
  ISHIMOTO Akinori
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
エイズの遺伝子治療に有効な導入遺伝子開発の基礎的研究
- Principal Investigator
  
  石本秋稔
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
マウス免疫不全症ウイルスの病原性に関与する遺伝子とその発症機構の解析
- Principal Investigator
  
  石本秋稔
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kyoto University

All 2013 2012 2011 2003 2002 2001 2000

All Journal Article Presentation

[Journal Article] HPV18 E1^E4 is assembled into aggresome-like compartment and involved in sequestration of viral oncoproteins2013
- Author(s)
  Kajitani N., Satsuka A., Yoshida S. and Sakai H.
- Journal Title
  
  Frontiers in Virology
  
  Volume: 4
- Data Source
  KAKENHI-PROJECT-23590540
[Journal Article] HPV18 E1^E4 is assembled into aggresome-like compartment and involved in sequestration of viral oncoproteins.2013
- Author(s)
  Kajitani N., Satsuka A., Yoshida S. and Sakai H.
- Journal Title
  
  Frontiers in Virology
  
  Volume: 4
- DOI
  10.3389/fmicb.2013.00251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590540
[Journal Article] Productive Lifecycle of Human Papillomaviruses that Depends Upon Squamous Epithelial Differentiation.2012
- Author(s)
  梶谷直子、佐塚文乃、川手章史、酒井博幸
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 3
- Data Source
  KAKENHI-PROJECT-23590540
[Journal Article] Productive lifecycle of human papillomavirus that depends upon squamous epithelial differentiation2012
- Author(s)
  Kajitani, N., Satsuka, A., Kawate, A., and Sakai, H.
- Journal Title
  
  Front. Microbiol
  
  Volume: 3 Pages: 152-152
- Data Source
  KAKENHI-PROJECT-23590540
[Journal Article] Productive lifecycle of human papillomaviruses that depends upon squamous epithelial differentiation.2012
- Author(s)
  Kajitani, N., Satsuka, A., Kawate, A., Sakai, H.
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 3, article 152 Pages: 1-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590540
[Journal Article] Downregulation of CD4 is required for maintenance of viral infectivity of HIV-1.2003
- Author(s)
  Tanaka, M., Ueno, T.Nakahara, T., Sasaki, K., Ishimoto, A., Sakai, H.
- Journal Title
  
  Virology 311
  
  Pages: 316-325
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214048
[Journal Article] Modulation of the cell division cycle by HPV18 E4.2002
- Author(s)
  Nakahara, T.Nishimura, A., Tanaka, M., Ueno, T., Ishimoto, A., Sakai, H.
- Journal Title
  
  J.Virol. 76
  
  Pages: 10914-10920
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214048
[Journal Article] Modification of virus infectivity by cytoplasmic tail of HIV-1 TM protein.2001
- Author(s)
  Iwatani, Y., Ueno, T., Nishimura, A., Zhang, X., Hattori, T., Ishimoto, A., Ito, M., Sakai, H.
- Journal Title
  
  Virus Res. 74
  
  Pages: 75-87
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214048
[Journal Article] Analysis of dominant-negative effects of mutant Env proteins of human immunodeficiency virus type 1.2001
- Author(s)
  Iwatani, Y., Kawano, K., Ueno, T., Tanaka, M., Ishimoto, A., Ito, M., Sakai, H.
- Journal Title
  
  Virology 286
  
  Pages: 453-53
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214048
[Journal Article] Mechanisms of human papillomavirus E2 mediated repression of viral oncogene expression and cervical cancer cell growth inhibition.2000
- Author(s)
  Nishimura, A., Ono, T., Ishimoto, A., Dowhanick, J.J., Frizzell, M.A., Howley, P.M., Sakai, H.
- Journal Title
  
  J.Virol. 74
  
  Pages: 3752-3760
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214048
[Journal Article] Functional association between the nef gene product and gag-pol region of HIV-1.2000
- Author(s)
  Ono, T., Iwatani, Y., Nishimura, A., Ishimoto, A, Sakai, H.
- Journal Title
  
  FEBS Letters 466
  
  Pages: 233-238
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214048
[Journal Article] Resistance to friend murine leukemia virus infection conferred by the Fv-4 gene is recessive but appears dominant from the effect of the immune system.2000
- Author(s)
  Zhang, F., Ya, L.T., Iwatani, Y., Higo, K., Suzuki, Y., Tanaka, M., Nakahara, T., Ono, T., Sakai, H., Kuribayashi, K., Ishimoto, A.
- Journal Title
  
  J.Virol. 74
  
  Pages: 6193-6197
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13214048
[Presentation] Human papillomavirus (HPV) E1^E4はaggresomeを形成する．2013
- Author(s)
  梶谷直子、酒井博幸
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590540
[Presentation] HPV E1^E4はアグリソームを形成しウイルス因子のタンパク量制御に関与する．2013
- Author(s)
  梶谷直子、酒井博幸
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590540
[Presentation] Human papillomavirus (HPV) E1^E4はaggresomeを形成する2013
- Author(s)
  梶谷直子,酒井博幸
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590540
[Presentation] HPV E1^E4はアグリソームを形成しウイルス因子のタンパク量制御に関与する2013
- Author(s)
  梶谷直子,酒井博幸
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590540
[Presentation] HPV 18E1^E4の新規機能の探索2012
- Author(s)
  梶谷直子,川手章史,酒井博幸
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590540
[Presentation] HPV 18E1^E4の新規機能の探索2012
- Author(s)
  梶谷直子、川手章史、酒井博幸
- Organizer
  第60回　日本ウイルス学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590540
[Presentation] HPV 18E1^E4の新規機能の探索：ビメンチンとの相互作用2012
- Author(s)
  梶谷直子、川手章史、酒井博幸
- Organizer
  第71回　日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590540
[Presentation] HPV 18E1^E4の新規機能の探索:ビメンチンとの相互作用2012
- Author(s)
  梶谷直子,川手章史,酒井博幸
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590540
[Presentation] HPVゲノムの複製メカニズムの解析2011
- Author(s)
  佐塚文乃,梶谷直子,川手章史,酒井博幸
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590540
[Presentation] Analysis of HPV genome replication2011
- Author(s)
  佐塚文乃,梶谷直子,川手章史,酒井博幸
- Organizer
  International Union of Microbiological Societies Congresses 2011
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-23590540
[Presentation] Identification of a function of Human papillomavirus 18 E1^E42011
- Author(s)
  梶谷直子,佐塚文乃,川手章史,酒井博幸
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590540
[Presentation] HPV 18 E1^E4, a viral gene product encoded by the early gene region of HPV genome, interacts with vimentin intermediate filaments in vitro and in vivo2011
- Author(s)
  梶谷直子,佐塚文乃,川手章史,酒井博幸
- Organizer
  International Union of Microbiological Societies Congresses 2011
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-23590540
[Presentation] HPV ゲノムの複製メカニズムの解析.2011
- Author(s)
  佐塚文乃、梶谷直子、川手章史、酒井博幸
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590540
[Presentation] HPV 18 E1^E4, a viral gene product encoded by the early gene region of HPV genome, interacts with vimentin intermediate filaments in vitro and in vivo.2011
- Author(s)
  梶谷直子、佐塚文乃、川手章史、酒井博幸
- Organizer
  International Union of Microbiological Societies Congresses 2011
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-23590540
[Presentation] Identification of a function of Human papillomavirus 18 E1^E4.2011
- Author(s)
  梶谷直子、佐塚文乃、川手章史、酒井博幸
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590540
[Presentation] Analysis of HPV genome replication.2011
- Author(s)
  佐塚文乃、梶谷直子、川手章史、酒井博幸
- Organizer
  International Union of Microbiological Societies Congresses 2011
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-23590540

1. ISHIMOTO Akinori (50073127)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
2. 柳川伸一 (70183978)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 前田道之 (20027329)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 日合弘 (10073131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Sakai Hiroyuki 酒井 博幸

SAKAI Hiroyuki 酒井 博幸

Research Projects

Research Products

Co-Researchers

Understandings of the HPV-induced tumorigenesis for developing anti-virus reagents.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of HPV regulatory gene function with organotypic culture of epithelial cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

皮膚三次元培養モデルにおけるヒトパピローマウイルス複製機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of HPV genes in keratinocyte organotypic culture system.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Studies on opportunistic oncogenesis in immunodeficient mouse by murine retroviruses.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ケラチノサイト三次元培養系を用いたヒトパピローマウイルス遺伝子機能の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Functional interaction between gene expression and DNA replication of HPV lifecylePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HPV16E2蛋白の子宮頸癌細胞増殖阻害の分子機構の解明とその応用に向けての研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

HIVのTM蛋白質サイトプラスミック・ドメインの細胞特異的機能に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Analysis of Fv-4 gene resistant to retrovirus infection

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

レトロウイルス感染に抵抗性遺伝子Fv‐4の作用機構の解析

Principal Investigator

Project Period (FY)

Research Category

Research Institution

エイズの遺伝子治療に有効な導入遺伝子開発の基礎的研究

Principal Investigator

Project Period (FY)

Research Category

Research Institution

マウス免疫不全症ウイルスの病原性に関与する遺伝子とその発症機構の解析

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] HPV18 E1^E4 is assembled into aggresome-like compartment and involved in sequestration of viral oncoproteins2013

Author(s)

Journal Title

Sakai Hiroyuki 酒井博幸

SAKAI Hiroyuki 酒井博幸