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Kozono Haruo  小園 晴生

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… Alternative Names

小園 晴生  コゾノ ハルオ

KOZONO Haruo  小園 晴生

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Researcher Number 80287482
Other IDs
Affiliation (Current) 2025: 北海道大学, 遺伝子病制御研究所, 客員研究員
Affiliation (based on the past Project Information) *help 2023: 東京理科大学, 研究推進機構生命医科学研究所, 准教授
2002 – 2003: 東京理科大学, 生命科学研究所, 助教授
1998 – 1999: 東京理科大学, 生命科学研究所, 助教授
Review Section/Research Field
Principal Investigator
Basic Section 49070:Immunology-related / Immunology / Biophysics
Keywords
Principal Investigator
MHC / TCR / アンタゴニスト / アゴニスト / CD / DSC / class II MHC / 制御性T細胞 / ユビキチン / antagonist … More / agonist / fluctuation / affinity / Stability / Peptide / アンダゴニスト / ゆらぎ / アフィニティ / 安定性 / ペプチド / folding / entropy / enthalpy / peptide exchange / 熱測定 / 酸性小胞 / 熱安定性 / ペプチド交換 / フォールディング / エントロピー / エンタルピー / ピプチド交換 Less
  • Research Projects

    (3 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (4 People)
  •  Analysis of regulatory T cells induced by ubiquitination of Class II MHC moleculesPrincipal Investigator

    • Principal Investigator
      小園 晴生
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Tokyo University of Science
  •  MHC/peptides stability and T cell activation-Biophysical bases of synapse formationPrincipal Investigator

    • Principal Investigator
      KOZONO Haruo
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      TOKYO UNIVERSITY OF SCIENCE
  •  Biophysical studies of TCR and their ligands, and interactions of them.Principal Investigator

    • Principal Investigator
      KOZONO Haruo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biophysics
    • Research Institution
      Science University of Tokyo

All 2023

All Journal Article Presentation

  • [Journal Article] Elucidation of binding mechanism, affinity and complex structure between mWT1 tumor-associated antigen peptide and HLA-A*24:022023

    • Author(s)
      Bekker GJ, Numoto N, Kawasaki M, Hayashi T, Yabuno S, Kozono Y, Shimizu T, Kozono H, Ito N, Oda M, Kamiya N
    • Journal Title

      Protein Science

      Volume: 32 Issue: 10

    • DOI

      10.1002/pro.4775

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K06600
  • [Journal Article] Ubiquitination of Major Histocompatibility Complex II Changes Its Immunological Recognition Structure2023

    • Author(s)
      Kozono Y, Kuramochi M, Sasaki YC, Kozono H
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 24 Issue: 23 Pages: 17083-17083

    • DOI

      10.3390/ijms242317083

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K06600, KAKENHI-PROJECT-23K26511
  • [Presentation] Preferential Induction of Regulatory T Cells by Ubiquitinated MHC II2023

    • Author(s)
      Yuko Kozono, Bicheng Fan, Satoshi Ueha, Haruo Kozono
    • Organizer
      日本免疫学会
    • Data Source
      KAKENHI-PROJECT-23K06600
  • 1.  NAKAMURA Haruki (80134485)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  FURUKAWA Koji (00297631)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  AZUMA Takachika (00028234)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  ODA Masayuki (20318231)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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