Ihara Sayoko 伊原さよ子

… Alternative Names

伊原さよ子イハラサヨコ

IHARA Sayoko 伊原さよ子

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Researcher Number	80292788
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院農学生命科学研究科(農学部), 助教
Affiliation (based on the past Project Information) *help	2019 – 2023: 東京大学, 大学院農学生命科学研究科(農学部), 助教 2016: 東京大学, 大学院農学生命科学研究科, 助教 2011 – 2014: 東京大学, 農学生命科学研究科, 助教 2007 – 2010: The University of Tokyo, 大学院・農学生命科学研究科, 助教 2006: 東京大学, 大学院農学生命科学研究科, 助手 1998 – 2005: 東京大学, 大学院・農学生命科学研究科, 助手 2001: 東京大学, 大学院・農学生命科学研究科, 教授
Review Section/Research Field	Principal Investigator Applied biochemistry / Basic Section 45060:Applied anthropology-related / Basic Section 38030:Applied biochemistry-related / 応用微生物学・応用生物化学 Except Principal Investigator 応用微生物学・応用生物化学 / Biological Sciences / Basic Section 45020:Evolutionary biology-related / Functional biochemistry
Keywords	Principal Investigator アクチン / 細胞膜 / 細胞骨格 / 嗅覚受容体 / 細胞応答 / シグナル伝達 / 精油 / 遺伝子多型 / GPCR / 異所発現 … More / 重合 / 生体膜 / アクチ / 癌 / SWAP-70 / 分化因子 / 突起伸長 / PC12 / 神経突起伸長 / 神経成長因子 … More Except Principal Investigator PIP_3 / Rac / ラッフリング / PI3キナーゼ / 嗅覚受容体 / Gタンパク質 / GEF / 増殖因子 / ホスファチジルイノシトール3キナーゼ / ホスファチジルイノシトール / イノシトールリン脂質 / 細胞運動 / 細胞接着 / PIP3 / ErbB3 / シグナル伝達 / 悪性腫瘍 / 印環細胞がん / 分子進化 / 味覚受容体 / フェロモン / アフリカ獣類 / 多型 / アフリカ獣上目 / 遺伝子重複 / 化学感覚 / 遺伝子ファミリー / マウス / 匂い / 嗅覚 / 生理活性物質 / リガンド / 匂い物質 / cell motility / cell adhesion / G protein / cell polarity / plextrin / phosphatidylinositol / PI3 kinase / 細胞極性 / プレクストリン / P13キナーゼ / growth factors / signal transduction / Ruffling / PH domain / phosphoinositides / 核外輸送 / ラッフル膜 / GTPase促進活性因子 / グアニンヌクレオチド交換因子 / 核移行 / PHドメイン / phospholipase / MAP kinase / polyphosphoinositides / adapter / differentiation / cell response / phosphatidylinositol kinase / phospholipids / 分化因子 / 細胞分化 / 細胞増殖 / 細胞応答 / ホスホリパーゼ / MAPキナーゼ / イノシトールリン酸 / アダプター / 分化 / 組織応答 / ホシファテシジルイノシトールキナーゼ / リン脂質 / アダプタータンパク質 / 初期エンドソーム / ゴルジ体 / リサイクリング / Muc4 / SWAP-70 / ErbB2 / ムチン / PI3-キナーゼ / アクチン / 脱分化 / cAMP / スキルスがん / ホスファリジルイノシトール / p38MAPキナーゼ / 点変異 / P38MAPキナーゼ / 細胞間相互作用 Less

香りの知覚・生理効果の個人差に嗅覚受容体遺伝子多型が及ぼす影響Principal Investigator
- Principal Investigator
  
  伊原さよ子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 45060:Applied anthropology-related
- Research Institution
  The University of Tokyo
環境への適応を特徴づける哺乳類嗅覚受容体遺伝子の探索とその機能解析
- Principal Investigator
  
  新村芳人
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 45020:Evolutionary biology-related
- Research Institution
  University of Miyazaki
Functional analysis of ectopically expressed olfactory receptorPrincipal Investigator
- Principal Investigator
  
  伊原さよ子
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38030:Applied biochemistry-related
- Research Institution
  The University of Tokyo
Identification of natural ligands for olfactory receptors and elucidation of biological function
- Principal Investigator
  
  Touhara Kazushige
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
The mechanism underlying the cell shape change mediated by an oligomerizing moleculePrincipal Investigator
- Principal Investigator
  
  IHARA Sayoko
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied biochemistry
- Research Institution
  The University of Tokyo
The molecular mechanism underlying the co-regulation of plasma membrane and F-actinPrincipal Investigator
- Principal Investigator
  
  IHARA Sayoko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied biochemistry
- Research Institution
  The University of Tokyo
細胞骨格・膜のダイナミズムにおけるSWAP-70の役割Principal Investigator
- Principal Investigator
  
  伊原さよ子
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  The University of Tokyo
がん細胞の分化・極性異常と生体膜シグナリング
- Principal Investigator
  
  福井泰久
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hoshi University
  The University of Tokyo
SWAP-70による癌化シグナルの解析とその応用Principal Investigator
- Principal Investigator
  
  伊原さよ子
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  The University of Tokyo
Studies on regulation of actin cytoskeleton by phosphatidylinositol-3 kinase and its application.
- Principal Investigator
  
  FUKUI Yasuhisa
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  The University of Tokyo
がんの発生発達に関わるイノシトールリン脂質情報伝達系の解析
- Principal Investigator
  
  FUKUI Yasuhisa
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Signal transduction to nucleus by phosphatidylinositol 3-kinase
- Principal Investigator
  
  FUKUI Yasuhisa
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  The University of Tokyo
新規神経細胞成長因子の検索とその性質の検討Principal Investigator
- Principal Investigator
  
  伊原さよ子
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  The University of Tokyo
Studies on signal transduction in generation and development of cancers.
- Principal Investigator
  
  FUKUI Yasuhisa
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2019 2016 2015 2013 2010 2009 2008 2006 2005

All Journal Article Presentation Book

[Book] Chemosensory Trasnduction2016
- Author(s)
  Touhara, K., Niimura, Y. and Ihara, S.
- Total Pages
  430
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-24227003
[Journal Article] Structural model for ligand binding and channel opening of an insect gustatory receptor.2022
- Author(s)
  Morinaga S, Nagata K, Ihara S, Yumita T, Niimura Y, Sato K, Touhara K
- Journal Title
  
  J Biol Chem
  
  Volume: 298 Issue: 11 Pages: 102573-102573
- DOI
  10.1016/j.jbc.2022.102573
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06359, KAKENHI-PROJECT-22K06341, KAKENHI-PROJECT-19H02531
[Journal Article] 香りのヒューメインな有効活用に向けた嗅覚基礎研究の進展2022
- Author(s)
  伊原さよ子、岡本雅子、白須未香、東原和成
- Journal Title
  
  アロマリサーチ
  
  Volume: 23 Pages: 3-8
- Data Source
  KAKENHI-PROJECT-19K05810
[Journal Article] Metabolism of odorant molecules in human nasal/oral cavity affects the odorant perception.2019
- Author(s)
  Ijichi C, Wakabayashi H, Sugiyama S, Ihara Y, Nogi Y, Nagashima A, Ihara S, Niimura Y, Shimizu Y, Kondo K, Touhara K
- Journal Title
  
  Chemical Senses
  
  Volume: 44 Issue: 7 Pages: 465-481
- DOI
  10.1093/chemse/bjz041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06359, KAKENHI-PROJECT-19K05810, KAKENHI-PROJECT-17K11353
[Journal Article] Ligand specificity and evolution of mammalian musk odor receptors: the effect of single receptor deletion on odor detection2016
- Author(s)
  Sato-Akuhara, N., Horio, N., Kato-Namba, A., Yoshikawa, K., Niimura, Y., Ihara, S., Shirasu, M.*, and Touhara, K.*
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 36 Issue: 16 Pages: 4482-4491
- DOI
  10.1523/jneurosci.3259-15.2016
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16J09029, KAKENHI-PROJECT-26850061, KAKENHI-PROJECT-24227003
[Journal Article] Scattering of MCF7 cells by heregulin beta-1 depends on the MEK and p38 MAP kinase pathway2013
- Author(s)
  Okoshi R, Shu CL, Ihara S, Fukui Y.
- Journal Title
  
  PLoS One
  
  Volume: 8 Pages: 53298-53298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580130
[Journal Article] Chemosensory signals and their receptors in the olfactory neural system2013
- Author(s)
  Ihara, S., Yoshikara, K. and Touhara, K.
- Journal Title
  
  Neuroscience
  
  Volume: 254 Pages: 45-60
- DOI
  10.1016/j.neuroscience.2013.08.063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24227003
[Journal Article] A mutant of SWAP-70. A phosphatidylinositoltrisphosphate binding protein, transforms mouse embryo fibroblasts, which is inhibited by sanguinarine2010
- Author(s)
  Y. Fukui, S. Ihara
- Journal Title
  
  PLoS One
  
  Volume: 5 Pages: 14180-14180
- Data Source
  KAKENHI-PROJECT-20580096
[Journal Article] Protein phosphatase type 1-interacting protein Ysw1 is involved in proper septin organization and prospore membrane formation during sporulation2009
- Author(s)
  M. Ishihara, Y. Suda, I. Inoue, T. Tanaka, T. Takahashi, X. D. Gao, Y. Fukui, S. Ihara, A. M. Neiman, H. Tachikawa
- Journal Title
  
  Eukaryot Cell
  
  Volume: 8 Pages: 1027-1037
- Data Source
  KAKENHI-PROJECT-20580096
[Journal Article] Protein phosphatase type 1-interacting protein Ysw1 is involved in proper septin organization and prospore membrane formation during sporulation2009
- Author(s)
  Ishihara M, et al.
- Journal Title
  
  Eukaryotic Cell 8
  
  Pages: 1027-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580096
[Journal Article] Direct binding of SWAP-70 to non-muscle actin is required for membrane ruffling2006
- Author(s)
  Ihara, S et al.
- Journal Title
  
  Journal of Cell Science 119
  
  Pages: 500-507
- Data Source
  KAKENHI-PROJECT-16780069
[Journal Article] Direct binding of SWAP-70 to non-muscle actin is required for membrane ruffling.2005
- Author(s)
  Ihara, S., et al.
- Journal Title
  
  Journal of Cell Science 119
  
  Pages: 500-507
- Data Source
  KAKENHI-PROJECT-17014015
[Presentation] 昆虫味覚受容体のリガンド結合様式および活性化機構の立体構造モデル2024
- Author(s)
  森永敏史、永田宏次、伊原さよ子、新村芳人、佐藤幸治、東原和成
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-19K05810
[Presentation] 酢酸イソアミルの香り知覚に寄与するヒト嗅覚受容体の同定2024
- Author(s)
  伊原さよ子、新村芳人、白須未香、岡本雅子、小川芳幸、高山文博、東原和成
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-19K05810
[Presentation] 酢酸イソアミルの香り知覚に関わる嗅覚受容体の解析2024
- Author(s)
  伊原さよ子
- Organizer
  第9回ケモビ研究会
- Data Source
  KAKENHI-PROJECT-23K05950
[Presentation] 酢酸イソアミルの香り知覚に寄与するヒト嗅覚受容体の同定2024
- Author(s)
  伊原さよ子、新村芳人、白須未香、岡本雅子、小川芳幸、高山文博、東原和成
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K05950
[Presentation] 酢酸イソアミルの匂い知覚に影響するヒト嗅覚受容体遺伝子多型2023
- Author(s)
  伊原さよ子、新村芳人、白須未香、岡本雅子、小川芳幸、高山文博、東原和成
- Organizer
  日本味と匂学会第57回大会
- Data Source
  KAKENHI-PROJECT-19K05810
[Presentation] 酢酸イソアミルの匂い知覚に影響するヒト嗅覚受容体遺伝子多型2023
- Author(s)
  伊原さよ子、新村芳人、白須未香、岡本雅子、小川芳幸、高山文博、東原和成
- Organizer
  日本味と匂学会第57回大会
- Data Source
  KAKENHI-PROJECT-23K05950
[Presentation] Effects of single olfactory receptor deletion on odor preference2016
- Author(s)
  Horio, N., Yoshikawa, K., Yoshihara, Y., and Touhara, K.
- Organizer
  17th International Symposium on Olfaction and Taste
- Place of Presentation
  横浜パシフィコ（神奈川県横浜市）
- Year and Date
  2016-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24227003
[Presentation] Structure-activity relationship and evolution of musk odor receptors in mammals2015
- Author(s)
  佐藤成見、白須未香、加藤綾、吉川敬一、新村芳人、伊原さよ子、東原和成
- Organizer
  Association for Chemoreception Sciences (AChemS) 37th Annual Meeting
- Place of Presentation
  Florida, U.S.A.
- Year and Date
  2015-04-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24227003
[Presentation] ムスク香を感知する嗅覚受容体の匂い応答性と進化2015
- Author(s)
  佐藤成見、白須未香、新村芳人、伊原さよ子、東原和成
- Organizer
  日本味と匂学会第49回大会
- Place of Presentation
  じゅうろくプラザ（岐阜県・岐阜市）
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-24227003
[Presentation] Rac1結合タンパク質DEF6の機能解析2008
- Author(s)
  加勢優子、高原有未、岡努、福井泰久、伊原さよ子
- Organizer
  日本分子生物学会、日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-20580096
[Presentation] Rap1 activation is required for DEF6-mediated cell shape change2008
- Author(s)
  Yuko Kase, Tsutomu Oka, Yasuhisa Fukui, Sayoko Ihara
- Organizer
  日本細胞生物学会大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-06-30
- Data Source
  KAKENHI-PROJECT-20580096

1. FUKUI Yasuhisa (00181248)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. Niimura Yoshihito (90396979)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. NAGATA Satoshi (40246682)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Touhara Kazushige (00280925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. Horio Nao (80726448)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 黒崎知博 (50178125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Yoshikawa Keiichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. Takai Yoshiki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Abe Takayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Sato Narumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. Kaneko Shoji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ihara Sayoko 伊原 さよ子

伊原 さよ子 イハラ サヨコ

IHARA Sayoko 伊原 さよ子

Research Projects

Research Products

Co-Researchers

香りの知覚・生理効果の個人差に嗅覚受容体遺伝子多型が及ぼす影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

環境への適応を特徴づける哺乳類嗅覚受容体遺伝子の探索とその機能解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of ectopically expressed olfactory receptorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of natural ligands for olfactory receptors and elucidation of biological function

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanism underlying the cell shape change mediated by an oligomerizing moleculePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The molecular mechanism underlying the co-regulation of plasma membrane and F-actinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

細胞骨格・膜のダイナミズムにおけるSWAP-70の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

がん細胞の分化・極性異常と生体膜シグナリング

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

SWAP-70による癌化シグナルの解析とその応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on regulation of actin cytoskeleton by phosphatidylinositol-3 kinase and its application.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

がんの発生発達に関わるイノシトールリン脂質情報伝達系の解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Signal transduction to nucleus by phosphatidylinositol 3-kinase

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規神経細胞成長因子の検索とその性質の検討Principal Investigator

Principal Investigator

Ihara Sayoko 伊原さよ子

伊原さよ子イハラサヨコ

IHARA Sayoko 伊原さよ子