Ota Yasuo 太田康男

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OTA Yasuo 太田康男

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Researcher Number	80292936
Other IDs
External Links
Affiliation (Current)	2025: 独立行政法人国立病院機構東埼玉病院(臨床研究部), 治験管理室, 院長 2025: 帝京大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2015 – 2017: 帝京大学, 医学部, 教授 2008 – 2013: Teikyo University, 医学部, 教授 2002 – 2006: The University of Tokyo, Faculty of Medicine, Research Associate, 医学部附属病院, 助手 1999 – 2001: 東京大学, 医学部・附属病院, 助手
Review Section/Research Field	Principal Investigator Infectious disease medicine / 膠原病・アレルギー・感染症内科学 / 内科学一般 / Biological Sciences
Keywords	Principal Investigator LPS / TLR4 / TLR / Cbl / 自然免疫 / mast cells / FcεRI / マスト細胞 / syk / cbl … More / MAPK / EGF / Grb2 / C.difficile / TLR5 / フラジェリン / CXCR4 / HIV / アストロサイト / cART / 骨密度 / LL motif / cellular localization / innate immunity / トラフィック / 細胞内輸送 / LLモチーフ / 細胞内分布 / histamine / FCεRI / TNF-α / PBL-2HC / F_<ce>RI / ヒスタミン / Ubiquitin / FcεRl / Syk / ユビキチン / プロトオンコジンCbl / 細胞内情報伝達 / EGF受容体 / tcdB / C. difficile / トレランス / CDI / MDP / NF-κB / 腸管上皮細胞 / 下痢症 / トキシンB / Clostridium difficile / 情報伝達 / SDI-α / エイズ脳症 / SDF-1α Less

Immunological activation and bone mineral loss in patients with HIVPrincipal Investigator
- Principal Investigator
  
  Ota Yasuo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Teikyo University
Regulation of intestinal epithelial cell activation by C. difficile lagellin and intestinal commensal bacteriaPrincipal Investigator
- Principal Investigator
  
  OTA Yasuo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Teikyo University
C.difficileフラジェリンが感染成立に果たす役割の研究Principal Investigator
- Principal Investigator
  
  OTA Yasuo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Teikyo University
Molecular mechanism of intracellular trafficking of TLR4Principal Investigator
- Principal Investigator
  
  OTA Yasuo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo
Molecular mechanisms in activation of mast cells through FcεRI anf Toll-like receptorPrincipal Investigator
- Principal Investigator
  
  OTA Yasuo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo
エイズ脳症の発症に関与する分子生物学的機序の解析Principal Investigator
- Principal Investigator
  
  太田康男
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
エイズ脳症の発症に関与する分子生物学的機序の解析Principal Investigator
- Principal Investigator
  
  太田康男
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
The role of the Cbl/Syk complex in FceRl-induced signaling cascade in mast cellsPrincipal Investigator
- Principal Investigator
  
  OTA Yasuo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
The function of p120^<cbl>, the product of c-cbl protooncogenePrincipal Investigator
- Principal Investigator
  
  OTA Yasuo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo

All 2017 2015 2013 2011 2010 2009 2008 2007 2006 2004 2003 Other

All Journal Article Presentation Other

[Journal Article] The Clinical Value of Cystatin C as a Marker of Renal Function in HIV Patients Receiving Dolutegravir.2017
- Author(s)
  Yoshino Y, Koga I, Seo K, Kitazawa T, Ota Y.
- Journal Title
  
  AIDS Res Hum Retroviruses.
  
  Volume: 33(11) Pages: 1080-1082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09582
[Journal Article] Duodenal Mycobacterium genavense infection in a patient with acquired immunodeficiency syndrome2013
- Author(s)
  Abe K, Yamamoto T, Ishii T, Kuyama Y, Koga I, Ota Y
- Journal Title
  
  Endoscopy
  
  Volume: 45 S2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591484
[Journal Article] Incidence of Clostridium difficile-associated diarrhea in patients using proton pump inhibitors : A Japanese study2013
- Author(s)
  Kitazawa T, Yoshino Y, Koga I, Isono A, Yamamoto T, Kuyama Y, Ota Y
- Journal Title
  
  Open Journal of Gastroenterology
  
  Volume: 3 Issue: 05 Pages: 276-280
- DOI
  10.4236/ojgas.2013.35047
- Data Source
  KAKENHI-PROJECT-23591484
[Journal Article] Changes in the Mean Platelet Volume Levels after Bloodstream Infection Have Prognostic Value2013
- Author(s)
  Kitazawa T, Yoshino Y, Tatsuno K, Ota Y, Yotsuyanagi H
- Journal Title
  
  Intern. Med.
  
  Volume: 52 Issue: 13 Pages: 1487-1493
- DOI
  10.2169/internalmedicine.52.9555
- NAID
  130003365698
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591484
[Journal Article] Pseudomonas putida bacteremia in adult patients : five case reports and a review of the literature2011
- Author(s)
  Yoshino Y、Kitazawa T、Kamimura M、Tatsuno K、Ota Y、Yotsuyanagi H
- Journal Title
  
  J Infect Chemother 17巻
  
  Pages: 278-282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591198
[Journal Article] わが国および帝京大学医学部附属病院におけるHIV感染症例の現状2010
- Author(s)
  太田康男
- Journal Title
  
  帝京医学雑誌
  
  Volume: 33 Pages: 219-224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591198
[Journal Article] Cryptococcal Pleuritis Containing a High Level of Adenosine Deaminase in a Patient with AIDS : A Case Report2010
- Author(s)
  Yoshino Y、Kitazawa T、Tatsuno K、Ota Y、Koike K
- Journal Title
  
  Respiration 79巻
  
  Pages: 153-156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591198
[Journal Article] わが国および帝京大学医学部附属病院におけるHIV感染症例の現状2010
- Author(s)
  太田康男、古賀一郎
- Journal Title
  
  帝京医学雑誌 33巻
  
  Pages: 219-224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591198
[Journal Article] An essential single amino acidof Toll-like receptor 4 that is pivotal for its signaltransduction and subcellular localization2009
- Author(s)
  Yanagimoto S、Tatsuno K、Okugawa S、Kitazawa T、Tsukada K、Koike K、KodamaT、Kimura S、Shibasaki Y、Ota Y
- Journal Title
  
  J.Biol Chem 284巻
  
  Pages: 3513-3520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591198
[Journal Article] Polymerase chain reaction assay for specific identification of Candida guilliermondii (Pichia guilliermondii)2009
- Author(s)
  Yamamura M、Makimura K、Fujisaki R、Satoh K、Kawakami S、Nishiya H、Ota Y
- Journal Title
  
  J Infect Chemother 15巻
  
  Pages: 214-218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591198
[Journal Article] Evaluation of a new rapid molecular diagnostic system for Plasmodium falciparum combined with DNA filter paper, loop-mediated isothermal amplification(LAMP) and melting curve analysis2009
- Author(s)
  Yamamura M、Makimura K、Ota Y
- Journal Title
  
  Jap.J.Infect.Dis 62巻
  
  Pages: 20-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591198
[Journal Article] Combined treatment with oral kanamycin and parenteral antibiotics for a case of persistent bacteremia and intestinal carriage with Campylobacter coli2008
- Author(s)
  Okada H、Kitazawa T、Harada S、Itoyama S、Hatakeyama S、Ota Y、Koike K
- Journal Title
  
  Intern Med 47巻
  
  Pages: 1363-1366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591198
[Journal Article] Relationship between initial dose of micafungin and its efficacy in patients with candidemia.2007
- Author(s)
  Ota Y, Tatsuno K, Okugawa S, Yanagimoto S, Kitazawa K, Fukushima A, Tsukada K, Koike K.
- Journal Title
  
  J Infect Chem. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] Relationship between initial dose of micafungin and its efficacy in patients with candidemia2007
- Author(s)
  太田康男
- Journal Title
  
  J Infect Chem. (印刷中)
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] Relationship between initiad dose of micafungin and its efficacy in patients with candidemia.2007
- Author(s)
  Ota Y, Tatsuno K, Okugawa S, Yanagimoto S, Uitazawa K
- Journal Title
  
  J Infect Chem (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] Relationship between initial dose of micafungin and its efficacy in patients with candidemia2007
- Author(s)
  太田, 康男
- Journal Title
  
  J Infect Chem. (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] A case of invasive central nervous system aspergillosis treated with micafungin with monitoring of micafungin concentrations in the cerebrosppinal fluid.2007
- Author(s)
  Okugawa, S., Ota, Y., Tatsun, K., Tsukada, K., Kishino, S., Koike, K.
- Journal Title
  
  Scand.J.Inf.Dis. (Published on line)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] Biphasic regulation of levofloxacin on lipopolysaccharide-induced IL-1β production.2007
- Author(s)
  Kitazawa T, Nakayama K, Okugawa S, Koike K, Shibasaki Y, Ota Y.
- Journal Title
  
  Life Sci 80
  
  Pages: 1572-1577
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] Dengue Hemorrhagic Shock and Disseminated Candidiasis.2007
- Author(s)
  Suzuki S, Kitazawa T, Ota Y, Okugawa S, Tsukada K, Nukui Y, Hatakeyama S, Yamaguchi D, Matsuse S, Ishii T, Matsubara T, Yamauchi C, Ota S, Yahagi N, Fukayama M, Koike K.
- Journal Title
  
  Intern Med (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] Expression and function of toll-kike receptors in human basophils.2006
- Author(s)
  Komiya, A., Nagase, H., Okugawa, S., Ota, Y., Suzukawa, M., Kawakami, A., Sekiya, T., Matsushima, K., Ohta, K., Hirai, K., Yamamoto, K., Yamaguchi, M.
- Journal Title
  
  Int Arch Allergy Immunol. 140 Suppl 1
  
  Pages: 23-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] Successful vancomycin desensitization with a combination of rapid and slow infusion methods.2006
- Author(s)
  Kitazawa, T., Ota, Y., Kada, N., Morisawa, Y., Yoshida, A., Koike, K., Kimura, S.
- Journal Title
  
  Intern Med. 45
  
  Pages: 317-321
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] Bacterial flagellin inhibits T cell receptor-mediated activation of T cells by inducing SOCS-1.2006
- Author(s)
  Okugawa, S., Tsukasa, K., Kitazawa, T., Koike, K., Kimura, S., Nagase, H., Hirai, K., Ota, Y.
- Journal Title
  
  Cell Microbiol. 8
  
  Pages: 1571-1580
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] Involvement of IRAK-M in Peptidoglycan-induced Tolerance in Macrophages.2004
- Author(s)
  Nakayama K, Okugawa S, Yanagimoto S, Kitazawa T, Tsukada K, Kawada M, Kimura S, Hiraib K, Takagaki Y, Ota Y.
- Journal Title
  
  J, Biol, Chem 2004, 279(8)
  
  Pages: 6629-6634
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591047
[Journal Article] Acute Hepatitis E with Elevated Creatine Phosphokinase.2003
- Author(s)
  Kitazawa T, Ota Y, Suzuki M, Morisawa Y, Shintani Y, Koike K, Kimura S.
- Journal Title
  
  Internal Med. 41
  
  Pages: 899-902
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591047
[Journal Article] Expression and Function of Toll-like Receptors in Eosinophils -Activation by the Toll-like receptor 7 Ligand R-848 -2003
- Author(s)
  Nagase H, Okugawa S, Ota Y, Yamaguchi M, Tomizawa H, Matsushima K, Ohta K, Yamamoto K, Hirai K.
- Journal Title
  
  J Immunol 171
  
  Pages: 3977-3982
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591047
[Journal Article] A patient with E.coli-induced pyelonephritis and sepsis who transiently exhibited symptoms associated with primary biliary cirrhosis.2003
- Author(s)
  Ohno N, Ota Y, Hatekeyama S, Yanagimoto S, Morisawa Y, Tsukada K, Koike K, Kimura S.
- Journal Title
  
  Internal Med 42(11)
  
  Pages: 114-118
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591047
[Journal Article] Janus Kinase 2 is involved in Lipopolysaccharide-Induced Activation of Macrophages.2003
- Author(s)
  Okugawa S, Ota Y, Kitazawa T, Nakayama K, Yanagimoto S, Tsukada K, Kawada M, Kimura S.
- Journal Title
  
  Am J Physiol Cell Physiol. 285
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591047
[Journal Article] Mitogen-activated protei kinases modulate chlamydial antigen-induced foam cell formation in macrophages.2003
- Author(s)
  Kitazawa T, Okugawa S, Nakayama K, Tsukada K, Kawada M, Yanagimoto S, Kimura S, Ota Y.
- Journal Title
  
  Atherosclerosis 4(2)
  
  Pages: 72-72
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591047
[Journal Article] Raf1 Plays a Pivotal Role in Lipopolysaccharide-Induced Activation of Dendritic Cells.2003
- Author(s)
  Nakayama K, Ota Y, Okugawa S, Ise N, Kitazawa T, Tsukada K, Kawada M, Yanagimoto S, Kimura S.
- Journal Title
  
  Biochem Biophys Res Commun. 308
  
  Pages: 353-360
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591047
[Presentation] 未治療男性HIV患者における骨密度低下の状況及び治療開始後の変化2017
- Author(s)
  吉野友祐, 三須恵太, 妹尾和憲, 古賀一郎, 北沢貴利, 太田康男
- Organizer
  日本エイズ学会
- Data Source
  KAKENHI-PROJECT-15K09582
[Presentation] The clinical value of cystatin C as a marker of renal function in HIV patients receiving dolutegravir.2017
- Author(s)
  Yusuke Yoshino, Keita Misu, Kazunori Seo, Ichiro Koga, Takatoshi Kitazawa, Yasuo Ota
- Organizer
  ID week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09582
[Presentation] The prevalence of bone loss and short term effect of anti-retroviral therapy on bone mineral density in male Japanese naïve patients with HIV.2017
- Author(s)
  Yusuke Yoshino, Keita Misu, Kazunori Seo, Ichiro Koga, Takatoshi Kitazawa, Yasuo Ota
- Organizer
  30th International Congress of Chemotherapy and Infection
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09582
[Presentation] 日本人HIV感染症患者におけるcART導入後の経過期間ごとの骨密度減少の推移2015
- Author(s)
  古賀一郎, 妹尾和憲, 北沢貴利, 太田康男
- Organizer
  第29回日本エイズ学会総会
- Place of Presentation
  東京ドームホテル（東京都文京区）
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-15K09582
[Presentation] Prevalence and risk factors for osteopenia and osteoporosis in male Japanese HIV patients2013
- Author(s)
  Ichiro Koga, Kazunori Seo, Yusuke Yoshino, Takatoshi Kitazawa, Yasuo Ota
- Organizer
  2nd Joint Meeting of the International Bone and Mineral society and The Japanese Society for Bone and Mineral Research
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-23591484
[Presentation] Clostridium Difficle Flagellin Activates Intestinal Epithelial Cells via Toll-like Receptor 52011
- Author(s)
  Yoshino Y、Kitazawa T、Ikeda M、Tatsuno K、Yanagimoto S、Okugawa S、Yotsuyanagi H、Ota Y
- Organizer
  13^<th> International Union Microbiological Societies
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-23591484
[Presentation] Does use of proton pump inhibitors increase incidence of Clostridium difficile-associated diarrhea?: a Japanese study2011
- Author(s)
  Kitazawa T、Yoshino Y、Yamamoto T、Kuyama Y、Ota Y
- Organizer
  The 51st Interscience Conference on Antimicrobial Agents and Chemotherapy
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-23591484
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1. 塚田訓久

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 川田真幹

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. OKUGAWA Shu (20376461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. 人見重美 (40292916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 北沢貴利

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ota Yasuo 太田 康男

OTA Yasuo 太田 康男

Research Projects

Research Products

Co-Researchers

Immunological activation and bone mineral loss in patients with HIVPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of intestinal epithelial cell activation by C. difficile lagellin and intestinal commensal bacteriaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

C.difficileフラジェリンが感染成立に果たす役割の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of intracellular trafficking of TLR4Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms in activation of mast cells through FcεRI anf Toll-like receptorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

エイズ脳症の発症に関与する分子生物学的機序の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

エイズ脳症の発症に関与する分子生物学的機序の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of the Cbl/Syk complex in FceRl-induced signaling cascade in mast cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The function of p120^<cbl>, the product of c-cbl protooncogenePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The Clinical Value of Cystatin C as a Marker of Renal Function in HIV Patients Receiving Dolutegravir.2017

Author(s)

Journal Title

Data Source

[Journal Article] Duodenal Mycobacterium genavense infection in a patient with acquired immunodeficiency syndrome2013

Author(s)

Journal Title

Data Source

[Journal Article] Incidence of Clostridium difficile-associated diarrhea in patients using proton pump inhibitors : A Japanese study2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Changes in the Mean Platelet Volume Levels after Bloodstream Infection Have Prognostic Value2013

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

Ota Yasuo 太田康男

OTA Yasuo 太田康男