YOSHIDA Kenji 吉田謙二

Researcher Number	80294122
Affiliation (based on the past Project Information) *help	2010 – 2012: 名城大学, 薬学部, 助教 1997 – 2002: 大阪大学, 微生物病研究所, 助手
Review Section/Research Field	Except Principal Investigator Immunology / General anatomy (including Histology/Embryology)
Keywords	Except Principal Investigator CD72 / CD100 / CD40 / セマフォリン / トランスジェニックマウス / Sema4A / T cell / SHP1 / T細胞 / LPS … More / B細胞 / 自己免疫 / シグナル伝達 / ノックアウトマウス / 副刺激分子 / LMP1 / EB-ウイルス / CD40リガンド / B cell / co-stimulatory molecules / 免疫 / 補助刺激分子 / Tim2 / 樹状細胞 / CD100 deficient mouse / semaphorin / CD40 signal / CD100欠損マウス / CD40シグナル / class switch / germinal center / autoimmunity / humoral immune response / CD40 ligand / 胚中心形成 / 体液性免疫反応 / クラススイッチ / 胚中心 / 体液性免疫 / 那須-ハコラ病 / 細胞分化・組織形成 / 精神疾患 / 脳内炎症 / プレキシン / 脳内ホメオスターシス / ミクログリア / 形態形成学 / 発生学 / マウス白血病ウイルス / CD4t欠損マウス / トランジェニックマウス / EBウイルス / 腫瘍免疫 / Bリンパ球 Less

Clarification on the role of semaphorin signal transduction mechanism regulating microglial function in brain homeostasis
- Principal Investigator
  
  YUKAWA Kazunori
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Meijo University
Positive and negative regulation of immune resonses through costimulatory interactions
- Principal Investigator
  
  KIKUTANI Hitoshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
リンパ球の正常及び異常増殖と副刺激シグナル
- Principal Investigator
  
  KIKUTANI Hitoshi
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
Regulation of immune responses and CD40 signal
- Principal Investigator
  
  KIKUTANI Hitoshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Immunology
- Research Institution
  Osaka University
Mechanisms of regulation of immune responses by CD40-CD40L interactions.
- Principal Investigator
  
  KIKUTANI Hitoshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University

All 2012 2011 2010

All Journal Article Presentation

[Journal Article] Scavenger receptors target glycolipids for natural killer T cell activation.2012
- Author(s)
  Stefan Freigang, Elise Landais, Victoria Zadorozhny, Lisa Kain, Kenji Yoshida, Yang Liu, Shenglou Deng, Wulf Palinski, Paul B. Savage, Albert Bendelac, Luc Teyton
- Journal Title
  
  J. Clin. Invest.
  
  Volume: 122 Pages: 3943-3954
- Data Source
  KAKENHI-PROJECT-22590195
[Journal Article] Ligand-receptor interaction between triterpenoids and the 11b-hydroxysteroid dehydrogenase type 2 (11bHSD2) enzyme predicts their toxic effects against tumorigenic r/m HM-SFME-1 cells.2011
- Author(s)
  Hideaki Yamaguchi, Tao Yu, Toshiro Noshita, Yumi Kidachi, Katsuyoshi Kamie, Kenji Yoshida, Tatsuo Akitaya, Hironori Umetsu and Kazuo Ryoyama
- Journal Title
  
  J Biol Chem.
  
  Volume: 286(42) Pages: 36888-36897
- Data Source
  KAKENHI-PROJECT-22590195
[Journal Article] Selective toxicity of glycyrrhetinic acid against tumorigenic r/m HM-SFME-1 cells is potentially attributed to downregulation of glutathione.2011
- Author(s)
  Hideaki Yamaguchi, Tao Yu, Yumi Kidachi, Tatsuo Akitaya, Kenji Yoshida, Katsuyoshi Kamie, Toshiro Noshita, Hironori Umetsu and Kazuo Ryoyama
- Journal Title
  
  Biochimie.
  
  Volume: 93 Pages: 1172-1178
- Data Source
  KAKENHI-PROJECT-22590195
[Journal Article] The diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinity.2010
- Author(s)
  Kenji Yoshida, Adam L. Corper, Rana Herro, Bana Jabri, Ian A. Wilson, and Luc Teyton
- Journal Title
  
  J. Clin. Invest.
  
  Volume: 120 (5) Pages: 1578-1590
- Data Source
  KAKENHI-PROJECT-22590195
[Journal Article] Deletion of Sema4D gene reduces intimal neovascularization and plaque growth in apolipoprotein E-deficient mice.2010
- Author(s)
  Yukawa K, Tanaka T, Kishino M, Yoshida K, Takeuchi N, et al.
- Journal Title
  
  International Journal of Molecular Medicine
  
  Volume: 26(1) Pages: 39-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590195
[Journal Article] Deletion of Sema4D gene reduces intimal neovascularization and plaque growth in apolipoprotein E-deficient mice. Int.2010
- Author(s)
  Kazunori Yukawa, Tetsuji Tanaka, Masanori Kishino, Kenji Yoshida, Noriko Takeuchi, Takuji Ito, Hyota Takamatsu, Hitoshi Kikutani, and Atsushi Kumanogoh
- Journal Title
  
  J. Mol. Med.
  
  Volume: 26 (1) Pages: 39-44
- Data Source
  KAKENHI-PROJECT-22590195
[Presentation] Molecular mechanism of semaphorin-induced cell death in postnatal tissue remodeling.2011
- Author(s)
  Takuji Ito, Tao Bai, Kenji Yoshida, Noriko Takeuchi, Hyota Takamatsu, Hitoshi Kikutani, Atsushi Kumanogoh, and Kazunori Yukawa
- Organizer
  第88回日本生理学学会
- Place of Presentation
  横浜
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22590195
[Presentation] Sema4D controls mouse postnatal vaginal development by inducing epithelial cell apoptosis through estrogen-dependent Sema4D and Plexin-B1 receptor activation.2011
- Author(s)
  Takuji Ito, Tao Bai, Tetsuji Tanaka, Takashi Ueyama, Kenji Yoshida, Noriko Takeuchi, Hyota Takamatsu, Hitoshi Kikutani, Atsushi Kumanogoh, andKazunori Yukawa
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22590195
[Presentation] Sema4D/CD100 deficiency leads to superior performance in mouse motor beha2011
- Author(s)
  Ito T, Yoshida K, Takeuchi N, Yukawa K
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, DC,米国
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PROJECT-22590195
[Presentation] Sema4D/CD100 deficiency leads to superior performance in mouse motor behavior.2011
- Author(s)
  Takuji Ito, Kenji Yoshida, Noriko Takeuchi, and Kazunori Yukawa
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, DC, 米国
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PROJECT-22590195
[Presentation] Molecular pathogenesis of central diabetes insipidus in a rat strain.2011
- Author(s)
  Noriko Takeuchi, Takuji Ito, Kenji Yoshida, and Kazunori Yukawa
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, DC, 米国
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-22590195
[Presentation] 新規尿崩症モデルにおけるバソプレシン刺激応答性.2011
- Author(s)
  青山栄里子、平川奈津美、松本信香、城正士、伊藤卓治、竹内典子、吉田謙二、湯川和典
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22590195
[Presentation] Novel mode of action of semaphorin 4D in tissue remodeling of mouse female genital organ2010
- Author(s)
  Ito T, (10人中1番目), Yoshida K, (5番目), Takeuchi N, (6番目), Yukawa K, (10番目)
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22590195
[Presentation] Mechanism of postnatal tissue remodeling induced by Sema4D/CD100 in mice.2010
- Author(s)
  Takuji Ito, Tao Bai, Tetsuji Tanaka, Takashi Ueyama, Kenji Yoshida, Noriko Takeuchi, Hyota Takamatsu, Hitoshi Kikutani, Atsushi Kumanogoh, and Kazunori Yukawa
- Organizer
  第87回日本生理学会
- Place of Presentation
  盛岡
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-22590195
[Presentation] Novel mode of action of semaphorin 4D in tissue remodeling of mouse female genital organ.2010
- Author(s)
  Takuji Ito, Tao Bai, Tetsuji Tanaka, Takashi Ueyama, Kenji Yoshida, Noriko Takeuchi, Hyota Takamatsu, Hitoshi Kikutani, Atsushi Kumanogoh, and Kazunori Yukawa
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22590195
[Presentation] Sema4D/CD100 deficiency leads to superior performance in mouse motor behavior.2010
- Author(s)
  Takuji Ito, Tao Bai, Tetsuji Tanaka, Kenji Yoshida, Noriko Takeuchi, Hitoshi Kikutani, Atsushi Kumanogoh, and Kazunori Yukawa
- Organizer
  第33回日本神経科学会
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-22590195
[Presentation] Effect of position beta57 of the diabetogenic MHC Class II molecule I-Ag7 on T cell repertoire and function.2010
- Author(s)
  Kenji Yoshida, Adam L. Corper, Bana Jabri, Ian A. Wilson and Luc Teyton
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-22590195

1. KIKUTANI Hitoshi (80161412)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. KUMANOGOH Atsushi (10294125)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. YASUI Teruhito (60283074)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. YUKAWA Kazunori (20301434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
5. TAKEUCHI Noriko (80076728)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results

YOSHIDA Kenji 吉田 謙二

Research Projects

Research Products

Co-Researchers

Clarification on the role of semaphorin signal transduction mechanism regulating microglial function in brain homeostasis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Positive and negative regulation of immune resonses through costimulatory interactions

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

リンパ球の正常及び異常増殖と副刺激シグナル

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Regulation of immune responses and CD40 signal

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of regulation of immune responses by CD40-CD40L interactions.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Scavenger receptors target glycolipids for natural killer T cell activation.2012

Author(s)

Journal Title

Data Source

[Journal Article] Ligand-receptor interaction between triterpenoids and the 11b-hydroxysteroid dehydrogenase type 2 (11bHSD2) enzyme predicts their toxic effects against tumorigenic r/m HM-SFME-1 cells.2011

Author(s)

Journal Title

Data Source

[Journal Article] Selective toxicity of glycyrrhetinic acid against tumorigenic r/m HM-SFME-1 cells is potentially attributed to downregulation of glutathione.2011

Author(s)

Journal Title

Data Source

[Journal Article] The diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinity.2010

Author(s)

Journal Title

Data Source

[Journal Article] Deletion of Sema4D gene reduces intimal neovascularization and plaque growth in apolipoprotein E-deficient mice.2010

Author(s)

Journal Title

Data Source

[Journal Article] Deletion of Sema4D gene reduces intimal neovascularization and plaque growth in apolipoprotein E-deficient mice. Int.2010

Author(s)

Journal Title

Data Source

[Presentation] Molecular mechanism of semaphorin-induced cell death in postnatal tissue remodeling.2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Sema4D controls mouse postnatal vaginal development by inducing epithelial cell apoptosis through estrogen-dependent Sema4D and Plexin-B1 receptor activation.2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Sema4D/CD100 deficiency leads to superior performance in mouse motor beha2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Sema4D/CD100 deficiency leads to superior performance in mouse motor behavior.2011

Author(s)

Organizer

Place of Presentation

Year and Date

YOSHIDA Kenji 吉田謙二