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YONEYAMA Hirohito  米山 弘人

ORCIDConnect your ORCID iD *help
… Alternative Names

米山 弘人  ヨネヤマ ヒロヒト

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Researcher Number 80294750
Other IDs
Affiliation (Current) 2025: 香川大学, 医学部, 協力研究員
Affiliation (based on the past Project Information) *help 2023: 香川大学, 医学部, 協力研究員
2019 – 2022: 香川大学, 医学部附属病院, 助教
2016 – 2018: 香川大学, 医学部, 助教
2010 – 2015: 香川大学, 医学部附属病院, 助教
1997 – 2000: Kagawa Medical University Dept.ofPhysiology 2, Assitant Professor, 医学部, 助手
Review Section/Research Field
Principal Investigator
Basic Section 59040:Nutrition science and health science-related / Laboratory medicine
Except Principal Investigator
Gastroenterology / General physiology / Basic Section 53010:Gastroenterology-related / Basic Section 52010:General internal medicine-related / Laboratory medicine
Keywords
Principal Investigator
マイクロRNA / 非アルコール性脂肪肝炎 / 非アルコール性脂肪性肝疾患 / 重症化予測 / 体組成計測 / マイクロアレイ / 内科 / 臨床 / 予後予測式 / 体組成 … More / エクソソーム / 予後予測 / NASH / NAFLD … More
Except Principal Investigator
肝細胞癌 / microRNA / マイクロRNA / EDCF / NO / ガレクチン9 / アポトーシス / Gal-9 / マイクロRNA / 転移性肝癌 / Galectin-9 / Galectin-9 microRNA / 胆管細胞癌 / エクソソーム / ガレクチン-9 / micro RNA / 自己免疫性肝疾患 / 原発性胆汁性胆管炎 / トランスレーショナルリサーチ / 分子生物学 / ガレクチン9 / 非アルコール性脂肪性肝炎 / Gal-9 / Gal-9 / apoptosis / hypertension / migration / angitensin / mast cell / superoxide / 高血圧 / 白血球接着・遊走 / アンギオテンシンII / 肥満細胞 / スーパーオキサイド / angina / isosobide dinitrate / nitroglycerin / EPR / ESR / oxygen relrease / hemoglohin / nitric oxide / 一酸化窒素 / 電子スピン共鳴 / 硝酸イソソルビド / ニトログリセリン / 狭心症 / 顕微分光 / 酸素放出 / ヘモグロビン / 一酸化窒素(NO) / 肝癌 / 細胞がん / 細胞周期 / 胃癌 / 胆のう癌 / 膵癌 / Cancer / Hepatocellular carcinoma / マイクロ RNA Less
  • Research Projects

    (10 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (24 People)
  •  Development of a method to predict the severity of nonalcoholic fatty liver disease by measuring body composition and microRNAPrincipal Investigator

    • Principal Investigator
      Yoneyama Hirohito
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Kagawa University
  •  Anti-tumor effect of Galectin-9 on metastatic hepatocellular carcinoma and its microRNA basis

    • Principal Investigator
      Masaki Tsutomu
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Kagawa University
  •  Prediction of prognosis targeting microRNAs in exosomes in primary biliary cholangitis

    • Principal Investigator
      Nomura Takako
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Kagawa University
  •  Development of a method to predict the severity of nonalcoholic fatty liver disease by exosomal microRNAPrincipal Investigator

    • Principal Investigator
      Yoneyama Hirohito
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Kagawa University
  •  Identification of microRNAs that regulate Galectin 9 to suppress nonalcoholic steatohepatitis progression

    • Principal Investigator
      Morishita Asahiro
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Kagawa University
  •  Basic study on treatment of hepatocellular carcinoma targetted of Gal-9 exosomes

    • Principal Investigator
      Masaki Tsutomu
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kagawa University
  •  Anti-tumor effect of galectin 9 in hepatocell carcinoma:Basic study

    • Principal Investigator
      masaki tsutomu
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kagawa University
  •  MicroRNAs as target molecular in metastatic liver cancer

    • Principal Investigator
      MASAKI Tsutomu
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kagawa University
  •  Endothelial function regulating migration of leukocytes to tissues

    • Principal Investigator
      KOSAKA Hiroaki
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General physiology
    • Research Institution
      Kagawa Medical University
  •  A new role of NO on the accelerating effect of oxygen supply to tissue

    • Principal Investigator
      KOSAKA Hiroaki
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      Kagawa Medical University
      Osaka University

All 2022 2021 2020 2019 2018 2017 2016 2015 2013

All Journal Article Presentation

  • [Journal Article] Identification of microRNA associated with the elimination of hepatitis C virus genotype 1b by direct‐acting antiviral therapies2021

    • Author(s)
      Yoneyama H, Morishita A, Iwama H, Fujita K, Takahiro Masaki, Tani J, Tadokoro T, Nomura T, Sakamoto T, Oura K, Takuma K, Nakahara M, Mimura S, Deguchi A, Oryu M, Tsutsui K, Himoto T, Shimotohno K, Wakita T, Kobara H, Masaki T
    • Journal Title

      Journal of Gastroenterology and Hepatology

      Volume: 36 Issue: 4 Pages: 1126-1135

    • DOI

      10.1111/jgh.15224

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08342, KAKENHI-PROJECT-20K08369, KAKENHI-PROJECT-20K11531, KAKENHI-PROJECT-18K15786
  • [Journal Article] Association between microRNA-527 and glypican-3 in hepatocellular carcinoma2021

    • Author(s)
      Nomura K, Kitanaka A, Iwama H, Tani J, Nomura T, Nakahara M, Ohura K, Tadokoro T, Fujita K, Mimura S, Yoneyama H, Kobara H, Morishita A, Okano K, Suzuki Y, Tsutsi K, Himoto T, Masaki T
    • Journal Title

      Oncology Letters

      Volume: 21 Issue: 3 Pages: 229-229

    • DOI

      10.3892/ol.2021.12490

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07880, KAKENHI-PROJECT-20K11531
  • [Journal Article] Comprehensive analysis of circulating microRNAs as predictive biomarkers for sorafenib therapy outcome in hepatocellular carcinoma2020

    • Author(s)
      Kohno Tomoki、Morishita Asahiro、Iwama Hisakazu、Fujita Koji、Tani Joji、Takuma Kei、Nakahara Mai、Oura Kyoko、Tadokoro Tomoko、Nomura Takako、Yoneyama Hirohito、Kato Kiyohito、Okano Keiichi、Suzuki Yasuyuki、Nishiyama Akira、Himoto Takashi、Masaki Tsutomu
    • Journal Title

      Oncology Letters

      Volume: 20 Issue: 2 Pages: 1727-1733

    • DOI

      10.3892/ol.2020.11696

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K11531
  • [Journal Article] Fibrosis Staging Using Direct Serum Biomarkers is Influenced by Hepatitis Activity Grading in Hepatitis C Virus Infection.2018

    • Author(s)
      Fujita K, Kuroda N, Morishita A, Oura K, Tadokoro T, Nomura T, Yoneyama H, Arai T, Himoto T, Watanabe S, Masaki T.
    • Journal Title

      J Clin Med

      Volume: 7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09361
  • [Journal Article] Serum miRNAs Predicting Sustained HBs Antigen Reduction 48 Weeks after Pegylated Interferon Therapy in HBe Antigen-Negative Patients.2018

    • Author(s)
      Fujita K, Mimura S, Iwama H, Nakahara M, Oura K, Tadokoro T, Nomura T, Tani J, Yoneyama H, Morishita A, Oryu M, Himoto T, Nishitsuji H, Shimotohno K, Omata M, Masaki T.
    • Journal Title

      Int J Mol Sci

      Volume: 19(7)

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09361
  • [Journal Article] Galectin-9 ameliorates fulminant liver injury.2017

    • Author(s)
      Tadokoro T, Morishita A, Sakamoto T, Fujihara S, Fujita K, Mimura S, Oura K, Nomura T, Tani J, Yoneyama H, Iwama H, Himoto T, Niki T, Hirashima M, Masaki T
    • Journal Title

      Mol Med Rep

      Volume: 16(1) Issue: 1 Pages: 36-42

    • DOI

      10.3892/mmr.2017.6606

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09361
  • [Journal Article] icroRNA profile of hepatic epithelioid hemangioendothelioma: A case report.2017

    • Author(s)
      Morishita A, Iwama H, Yoneyama H, Sakamoto T, Fujita K, Nomura T, Tani J, Miyoshi H, Fujihara S, Nishiyama N, Kobara H, Mori H, Yamamoto N, Okano K, Suzuki Y, Ibuki E, Haba R, Himoto T, Masaki T.
    • Journal Title

      Oncol Lett

      Volume: 13(3) Issue: 3 Pages: 1655-1659

    • DOI

      10.3892/ol.2017.5643

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09361
  • [Journal Article] Galectin-9: An anticancer molecule for gallbladder carcinoma.2016

    • Author(s)
      Tadokoro T, Morishita A, Fujihara S, Iwama H, Niki T, Fujita K, Akashi E, Mimura S, Oura K, Sakamoto T, Nomura T, Tani J, Miyoshi H, Yoneyama H, Himoto T, Hirashima M, Masaki T.
    • Journal Title

      Int J Oncol

      Volume: 48 Issue: 3 Pages: 1165-1174

    • DOI

      10.3892/ijo.2016.3347

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460592, KAKENHI-PROJECT-16K09361
  • [Journal Article] Galectin-9: An anticancer molecule for gallbladder carcinoma2016

    • Author(s)
      Tadokoro T, Morishita A, Fujihara S, Iwama H, Niki T, Fujita K, Akashi E, Mimura S, Oura K, Sakamoto T, Nomura T, Tani J, Miyoshi H, Yoneyama H, Himoto T, Hirashima M, Masaki T
    • Journal Title

      Int J Oncol

      Volume: 48 Pages: 1165-1174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460998
  • [Journal Article] Galectin-9 suppresses the proliferation of gastric cancer cells in vitro2016

    • Author(s)
      Takano J, Morishita A, Fujihara S, Iwama H, Kokado F, Fujikawa K, Fujita K, Chiyo T, Tadokoro T, Sakamoto T, Nomura T, Tani J, Miyoshi H, Yoneyama H, Kobara H, Mori H, Niki T, Hirashima M, Masaki T
    • Journal Title

      Oncol Rep

      Volume: 35 Pages: 851-860

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460998
  • [Journal Article] Galectin-9 suppresses the proliferation of gastric cancer cells in vitro.2016

    • Author(s)
      Takano J, Morishita A, Fujihara S, Iwama H, Kokado F, Fujikawa K, Fujita K, Chiyo T, Tadokoro T, Sakamoto T, Nomura T, Tani J, Miyoshi H, Yoneyama H, Kobara H, Mori H, Niki T, Hirashima M, Masaki T.
    • Journal Title

      Oncol Rep

      Volume: 35 Issue: 2 Pages: 851-860

    • DOI

      10.3892/or.2015.4452

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460592, KAKENHI-PROJECT-16K09361
  • [Journal Article] Galectin-9 suppresses the growth of hepatocellular carcinoma via apoptosis in vitro and in vivo2015

    • Author(s)
      Fujita K, Iwama H, Sakamoto T, Okura R, Kobayashi K, Takano J, Katsura A, Tatsuta M, Maeda E, Mimura S, Nomura T, Tani J, Miyoshi H, Morishita A, Yoneyama H, Yamana Y, Himoto T, Okano K, Suzuki Y, Niki T, Hirashima M, Masaki T
    • Journal Title

      Int J Oncol

      Volume: 46 Pages: 2419-2430

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460998
  • [Journal Article] Galectin-9 suppresses the growth of hepatocellular carcinoma via apoptosis in vitro and in vivo.2015

    • Author(s)
      Fujita K, Iwama H, Sakamoto T, Okura R, Kobayashi K, Takano J, Katsura A, Tatsuta M, Maeda E, Mimura S, Nomura T, Tani J, Miyoshi H, Morishita A, Yoneyama H, Yamana Y, Himoto T, Okano K, Suzuki Y, Niki T, Hirashima M, Masaki T.
    • Journal Title

      Int J Oncol.

      Volume: 46 Issue: 6 Pages: 2419-2430

    • DOI

      10.3892/ijo.2015.2941

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460592, KAKENHI-PROJECT-25460998
  • [Journal Article] Galectin-9 prolongs the survival of septic mice by expanding Tim-3-expressing natural killer T cells and PDCA-1+ CD11c+ macrophages2013

    • Author(s)
      Kadowaki T, Morishita A, Niki T, Hara J, Sato M, Tani J, Miyoshi H, Yoneyama H, Masaki T, Hattori T, Matsukawa A, Hirashima M.
    • Journal Title

      Crit Care

      Volume: 17(6) Issue: 6

    • DOI

      10.1186/cc13147

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23256004, KAKENHI-PROJECT-25460998
  • [Presentation] Prediction of Liver Fibrosis and Carcinogenesis by Body Comparison Analysis by Bioelectrical Impedance Analysis2022

    • Author(s)
      Hirohito Yoneyama, Toshiaki Nakatsu, Naohito Uchida, Yuuko Bandou, Asahiro Morishita , Joji Tani, Koji Fujita, Takako Nomura, Teppei Sakamoto, Shima Mimura, Tomoko Tadokoro, Kyoko Oura, Mai Nakahara, Kei Takuma, Akihiro Deguchi, Takashi Himoto, Tsutomu Masaki
    • Organizer
      The Asian Pacific Association for the Study of the Liver: APASL Oncology 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K11531
  • [Presentation] DAA治療によるウイルス排除後にも肝炎が持続あるいは再燃するC型肝炎患者の血清マイクロRNAの解析2020

    • Author(s)
      米山弘人、岩間和久、森下朝洋、谷丈二、野村貴子、藤田浩二、田所智子、大浦杏子、三村志麻、中原麻衣、琢磨慧、坂本鉄平、出口章広、樋本尚志、正木勉
    • Organizer
      第106回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-20K11531
  • [Presentation] 生体電気インピーダンス法を用いた体組成計測によるNAFLD/NASHの肝線維化進展および治療効果予測2019

    • Author(s)
      米山弘人、森下朝洋、谷丈二、野村貴子、坂本鉄平、藤田浩二、田所智子、大浦杏子、中原麻衣、琢磨慧、出口章広、樋本尚志、正木勉
    • Organizer
      第43回日本肝臓学会西部会
    • Data Source
      KAKENHI-PROJECT-17K08984
  • [Presentation] Assessment of the progression of liver fibrosis by body comparison analysis by bioelectrical impedance analysis2019

    • Author(s)
      Hirohito Yoneyama, Asahiro Morishita, Takako Nomura, Teppei Sakamoto, Koji Fujita, Shima, Mimura, Tomoko Tadokoro, Kyoko Oura, Mai Nakahara, Kei Takuma, Joji Tani, Akihiro Deguchi, Takashi Himoto, Tsutomu Masaki
    • Organizer
      The Asian Pacific Association for the Study of the Liver
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08984
  • [Presentation] Assessment of the progression of liver fibrosis by body comparison analysis by bioelectrical impedance analysis2019

    • Author(s)
      Hirohito Yoneyama, Asahiro Morishita , Joji Tani, Takako Nomura, Teppei Sakamoto, Koji Fujita, Shima Mimura, Tomoko Tadokoro, Kyoko Oura, Mai Nakahara, Kei Takuma, Akihiro Deguchi, Takashi Himoto, Tsutomu MASAKI
    • Organizer
      APASL STC 2019 TOKYO
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08984
  • [Presentation] miR-762はDAA治療経過中のゲノタイプ1型HCV排除に際して血清中に増加する2018

    • Author(s)
      米山弘人、森下朝洋、藤田浩二、野村貴子、坂本鉄平、田所智子、大浦杏子、谷 丈二、出口章広、樋本尚志、三村志麻、正木 勉
    • Organizer
      第22回日本肝臓学会大会
    • Data Source
      KAKENHI-PROJECT-16K09361
  • [Presentation] C型肝炎起因性肝細胞癌におけるバイオマーカーとしての血清miR-125a-5pの有用性2018

    • Author(s)
      大浦杏子、田所智子、藤田浩二、三村志麻、坂本鉄平、野村貴子、森下朝洋、米山弘人、正木 勉
    • Organizer
      第22回日本肝臓学会大会
    • Data Source
      KAKENHI-PROJECT-16K09361
  • [Presentation] Serum Concentration of Galectin-9 Correlates to Liver Fibrosis.2017

    • Author(s)
      Fujita K, Morishita A, Yoneyama H, Niki T, Nishimoto N, Himoto T, Masaki T.
    • Organizer
      APASL STC 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09361
  • [Presentation] 胆管細胞癌におけるガレクチン-9 による増殖抑制効果の検討2015

    • Author(s)
      小林聖幸、藤田浩二、大倉亮一、山下拓磨、西岡智子、谷 丈二、三好久昭、坂本鉄平、藤森崇行、加藤清仁、鎌田英紀、森下朝洋、米山弘人、正木 勉
    • Organizer
      第51回日本肝臓学会総会
    • Place of Presentation
      熊本市
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-25460998
  • [Presentation] 劇症肝炎におけるガレクチン-9の有効性について2015

    • Author(s)
      田所智子、森下朝洋、米山弘人、三好久昭、谷 丈二、野村貴子、坂本鉄平、藤田浩二、三村志麻、明石瑛美子、大浦杏子、正木 勉
    • Organizer
      第51回日本肝臓学会総会
    • Place of Presentation
      熊本市
    • Year and Date
      2015-05-22
    • Data Source
      KAKENHI-PROJECT-25460998
  • 1.  MASAKI Tsutomu (30335848)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 18 results
  • 2.  IWAMA Hisakazu (20398035)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 5 results
  • 3.  Morishita Asahiro (60423430)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 7 results
  • 4.  Nomura Takako (70645415)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 5.  藤田 浩二 (50749421)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 7 results
  • 6.  TANI Joji (00596075)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 7.  HIMOTO Takashi (20325343)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 8.  KOSAKA Hiroaki (60158897)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  小原 英幹 (10612476)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 10.  坂本 鉄平 (30769328)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  DEGUCHI Akihiro (30380174)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  SUZUKI Yasuyuki (40304092)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  MIYOSHI Hisaaki (40592316)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 14.  HIRASHIMA Mitsuomi (70109700)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 15.  SEIYAMA Akitoshi (70206605)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  FUJII Shigemoto (00325333)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  YAMAMOTO Akira (70314911)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  森 宏仁 (20568844)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 19.  仁木 敏朗 (40558508)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 20.  田所 智子 (50813177)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  大浦 杏子 (80834639)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  MASAKI Takahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  北中 明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  服部 俊夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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