YONEYAMA Hirohito 米山弘人

Researcher Number	80294750
Other IDs
Affiliation (Current)	2022: 香川大学, 医学部, 協力研究員
Affiliation (based on the past Project Information) *help	2019 – 2021: 香川大学, 医学部附属病院, 助教 2016 – 2018: 香川大学, 医学部, 助教 2010 – 2015: 香川大学, 医学部附属病院, 助教 1997 – 2000: Kagawa Medical University Dept.ofPhysiology 2, Assitant Professor, 医学部, 助手
Review Section/Research Field	Principal Investigator Laboratory medicine / Basic Section 59040:Nutrition science and health science-related Except Principal Investigator Gastroenterology / General physiology / Laboratory medicine / Basic Section 52010:General internal medicine-related / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 非アルコール性脂肪性肝疾患 / 非アルコール性脂肪肝炎 / マイクロRNA / NAFLD / NASH / 予後予測 / エクソソーム / 体組成 / 予後予測式 / 臨床 … More / 内科 / マイクロアレイ / 体組成計測 / 重症化予測 … More Except Principal Investigator マイクロRNA / microRNA / 肝細胞癌 / 転移性肝癌 / マイクロＲＮＡ / Gal-9 / アポトーシス / ガレクチン9 / NO / EDCF / マイクロ RNA / Hepatocellular carcinoma / Cancer / 膵癌 / 胆のう癌 / 胃癌 / 細胞周期 / 細胞がん / 肝癌 / 一酸化窒素(NO) / ヘモグロビン / 酸素放出 / 顕微分光 / 狭心症 / ニトログリセリン / 硝酸イソソルビド / 電子スピン共鳴 / 一酸化窒素 / nitric oxide / hemoglohin / oxygen relrease / ESR / EPR / nitroglycerin / isosobide dinitrate / angina / スーパーオキサイド / 肥満細胞 / アンギオテンシンII / 白血球接着・遊走 / 高血圧 / superoxide / mast cell / angitensin / migration / hypertension / apoptosis / Ｇａｌ－９ / Ｇａｌ-9 / 非アルコール性脂肪性肝炎 / ガレクチン９ / 分子生物学 / トランスレーショナルリサーチ / 原発性胆汁性胆管炎 / 自己免疫性肝疾患 / micro RNA / ガレクチン-9 / エクソソーム / 胆管細胞癌 / Galectin-9 microRNA / Galectin-9 Less

Development of a method to predict the severity of nonalcoholic fatty liver disease by measuring body composition and microRNAPrincipal Investigator
- Principal Investigator
  
  米山弘人
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kagawa University
Anti-tumor effect of Galectin-9 on metastatic hepatocellular carcinoma and its microRNA basis
- Principal Investigator
  
  Masaki Tsutomu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kagawa University
Prediction of prognosis targeting microRNAs in exosomes in primary biliary cholangitis
- Principal Investigator
  
  Nomura Takako
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kagawa University
Development of a method to predict the severity of nonalcoholic fatty liver disease by exosomal microRNAPrincipal Investigator
- Principal Investigator
  
  Yoneyama Hirohito
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kagawa University
Identification of microRNAs that regulate Galectin 9 to suppress nonalcoholic steatohepatitis progression
- Principal Investigator
  
  Morishita Asahiro
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kagawa University
Basic study on treatment of hepatocellular carcinoma targetted of Gal-9 exosomes
- Principal Investigator
  
  Masaki Tsutomu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kagawa University
Anti-tumor effect of galectin 9 in hepatocell carcinoma:Basic study
- Principal Investigator
  
  masaki tsutomu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kagawa University
MicroRNAs as target molecular in metastatic liver cancer
- Principal Investigator
  
  MASAKI Tsutomu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kagawa University
Endothelial function regulating migration of leukocytes to tissues
- Principal Investigator
  
  KOSAKA Hiroaki
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  General physiology
- Research Institution
  Kagawa Medical University
A new role of NO on the accelerating effect of oxygen supply to tissue
- Principal Investigator
  
  KOSAKA Hiroaki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Kagawa Medical University
  Osaka University

All 2021 2020 2019 2018 2017 2016 2015 2013

All Journal Article Presentation

[Journal Article] Identification of microRNA associated with the elimination of hepatitis C virus genotype 1b by direct-acting antiviral therapies2021
- Author(s)
  Yoneyama H, Morishita A, Iwama H, Fujita K, Takahiro Masaki, Tani J, Tadokoro T, Nomura T, Sakamoto T, Oura K, Takuma K, Nakahara M, Mimura S, Deguchi A, Oryu M, Tsutsui K, Himoto T, Shimotohno K, Wakita T, Kobara H, Masaki T
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 36 Pages: 1126-1135
- DOI
  10.1111/jgh.15224
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08342, KAKENHI-PROJECT-20K08369, KAKENHI-PROJECT-20K11531, KAKENHI-PROJECT-18K15786
[Journal Article] Association between microRNA?527 and glypican?3 in hepatocellular carcinoma2021
- Author(s)
  Nomura K, Kitanaka A, Iwama H, Tani J, Nomura T, Nakahara M, Ohura K, Tadokoro T, Fujita K, Mimura S, Yoneyama H, Kobara H, Morishita A, Okano K, Suzuki Y, Tsutsi K, Himoto T, Masaki T
- Journal Title
  
  Oncology Letter
  
  Volume: 21 Pages: 229-229
- DOI
  10.3892/ol.2021.12490
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07880, KAKENHI-PROJECT-20K11531
[Journal Article] Comprehensive analysis of circulating microRNAs as predictive biomarkers for sorafenib therapy outcome in hepatocellular carcinoma2020
- Author(s)
  Kohno Tomoki、Morishita Asahiro、Iwama Hisakazu、Fujita Koji、Tani Joji、Takuma Kei、Nakahara Mai、Oura Kyoko、Tadokoro Tomoko、Nomura Takako、Yoneyama Hirohito、Kato Kiyohito、Okano Keiichi、Suzuki Yasuyuki、Nishiyama Akira、Himoto Takashi、Masaki Tsutomu
- Journal Title
  
  Oncology Letters
  
  Volume: 20 Pages: 1727-1733
- DOI
  10.3892/ol.2020.11696
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11531
[Journal Article] Fibrosis Staging Using Direct Serum Biomarkers is Influenced by Hepatitis Activity Grading in Hepatitis C Virus Infection.2018
- Author(s)
  Fujita K, Kuroda N, Morishita A, Oura K, Tadokoro T, Nomura T, Yoneyama H, Arai T, Himoto T, Watanabe S, Masaki T.
- Journal Title
  
  J Clin Med
  
  Volume: 7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] Serum miRNAs Predicting Sustained HBs Antigen Reduction 48 Weeks after Pegylated Interferon Therapy in HBe Antigen-Negative Patients.2018
- Author(s)
  Fujita K, Mimura S, Iwama H, Nakahara M, Oura K, Tadokoro T, Nomura T, Tani J, Yoneyama H, Morishita A, Oryu M, Himoto T, Nishitsuji H, Shimotohno K, Omata M, Masaki T.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 19(7)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] Galectin-9 ameliorates fulminant liver injury.2017
- Author(s)
  Tadokoro T, Morishita A, Sakamoto T, Fujihara S, Fujita K, Mimura S, Oura K, Nomura T, Tani J, Yoneyama H, Iwama H, Himoto T, Niki T, Hirashima M, Masaki T
- Journal Title
  
  Mol Med Rep
  
  Volume: 16(1) Pages: 36-42
- DOI
  10.3892/mmr.2017.6606
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] icroRNA profile of hepatic epithelioid hemangioendothelioma: A case report.2017
- Author(s)
  Morishita A, Iwama H, Yoneyama H, Sakamoto T, Fujita K, Nomura T, Tani J, Miyoshi H, Fujihara S, Nishiyama N, Kobara H, Mori H, Yamamoto N, Okano K, Suzuki Y, Ibuki E, Haba R, Himoto T, Masaki T.
- Journal Title
  
  Oncol Lett
  
  Volume: 13(3) Pages: 1655-1659
- DOI
  10.3892/ol.2017.5643
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09361
[Journal Article] Galectin-9: An anticancer molecule for gallbladder carcinoma.2016
- Author(s)
  Tadokoro T, Morishita A, Fujihara S, Iwama H, Niki T, Fujita K, Akashi E, Mimura S, Oura K, Sakamoto T, Nomura T, Tani J, Miyoshi H, Yoneyama H, Himoto T, Hirashima M, Masaki T.
- Journal Title
  
  Int J Oncol
  
  Volume: 48 Pages: 1165-1174
- DOI
  10.3892/ijo.2016.3347
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460592, KAKENHI-PROJECT-16K09361
[Journal Article] Galectin-9: An anticancer molecule for gallbladder carcinoma2016
- Author(s)
  Tadokoro T, Morishita A, Fujihara S, Iwama H, Niki T, Fujita K, Akashi E, Mimura S, Oura K, Sakamoto T, Nomura T, Tani J, Miyoshi H, Yoneyama H, Himoto T, Hirashima M, Masaki T
- Journal Title
  
  Int J Oncol
  
  Volume: 48 Pages: 1165-1174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460998
[Journal Article] Galectin-9 suppresses the proliferation of gastric cancer cells in vitro2016
- Author(s)
  Takano J, Morishita A, Fujihara S, Iwama H, Kokado F, Fujikawa K, Fujita K, Chiyo T, Tadokoro T, Sakamoto T, Nomura T, Tani J, Miyoshi H, Yoneyama H, Kobara H, Mori H, Niki T, Hirashima M, Masaki T
- Journal Title
  
  Oncol Rep
  
  Volume: 35 Pages: 851-860
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460998
[Journal Article] Galectin-9 suppresses the proliferation of gastric cancer cells in vitro.2016
- Author(s)
  Takano J, Morishita A, Fujihara S, Iwama H, Kokado F, Fujikawa K, Fujita K, Chiyo T, Tadokoro T, Sakamoto T, Nomura T, Tani J, Miyoshi H, Yoneyama H, Kobara H, Mori H, Niki T, Hirashima M, Masaki T.
- Journal Title
  
  Oncol Rep
  
  Volume: 35 Pages: 851-60
- DOI
  10.3892/or.2015.4452
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460592, KAKENHI-PROJECT-16K09361
[Journal Article] Galectin-9 suppresses the growth of hepatocellular carcinoma via apoptosis in vitro and in vivo2015
- Author(s)
  Fujita K, Iwama H, Sakamoto T, Okura R, Kobayashi K, Takano J, Katsura A, Tatsuta M, Maeda E, Mimura S, Nomura T, Tani J, Miyoshi H, Morishita A, Yoneyama H, Yamana Y, Himoto T, Okano K, Suzuki Y, Niki T, Hirashima M, Masaki T
- Journal Title
  
  Int J Oncol
  
  Volume: 46 Pages: 2419-2430
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460998
[Journal Article] Galectin-9 suppresses the growth of hepatocellular carcinoma via apoptosis in vitro and in vivo.2015
- Author(s)
  Fujita K, Iwama H, Sakamoto T, Okura R, Kobayashi K, Takano J, Katsura A, Tatsuta M, Maeda E, Mimura S, Nomura T, Tani J, Miyoshi H, Morishita A, Yoneyama H, Yamana Y, Himoto T, Okano K, Suzuki Y, Niki T, Hirashima M, Masaki T.
- Journal Title
  
  Int J Oncol
  
  Volume: 46 Pages: 2419-2430
- DOI
  10.3892/ijo.2015.2941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460592, KAKENHI-PROJECT-25460998
[Journal Article] Galectin-9 prolongs the survival of septic mice by expanding tim-3-expressing natural killer T cells and PDCA-1+ CD11c+ macrophages.2013
- Author(s)
  Kadowaki T, Morishita A, Niki T, Hara J, Sato M, Tani J, Miyoshi H, Yoneyama H, Masaki T, Hattori T, Matsukawa A, Hirashima M.
- Journal Title
  
  Crit Care
  
  Volume: 17(6)
- DOI
  10.1186/cc13147
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23256004, KAKENHI-PROJECT-25460998
[Presentation] DAA治療によるウイルス排除後にも肝炎が持続あるいは再燃するC型肝炎患者の血清マイクロRNAの解析2020
- Author(s)
  米山弘人、岩間和久、森下朝洋、谷丈二、野村貴子、藤田浩二、田所智子、大浦杏子、三村志麻、中原麻衣、琢磨慧、坂本鉄平、出口章広、樋本尚志、正木勉
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-20K11531
[Presentation] 生体電気インピーダンス法を用いた体組成計測によるNAFLD/NASHの肝線維化進展および治療効果予測2019
- Author(s)
  米山弘人、森下朝洋、谷丈二、野村貴子、坂本鉄平、藤田浩二、田所智子、大浦杏子、中原麻衣、琢磨慧、出口章広、樋本尚志、正木勉
- Organizer
  第４３回日本肝臓学会西部会
- Data Source
  KAKENHI-PROJECT-17K08984
[Presentation] Assessment of the progression of liver fibrosis by body comparison analysis by bioelectrical impedance analysis2019
- Author(s)
  Hirohito Yoneyama, Asahiro Morishita, Takako Nomura, Teppei Sakamoto, Koji Fujita, Shima, Mimura, Tomoko Tadokoro, Kyoko Oura, Mai Nakahara, Kei Takuma, Joji Tani, Akihiro Deguchi, Takashi Himoto, Tsutomu Masaki
- Organizer
  The Asian Pacific Association for the Study of the Liver
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08984
[Presentation] Assessment of the progression of liver fibrosis by body comparison analysis by bioelectrical impedance analysis2019
- Author(s)
  Hirohito Yoneyama, Asahiro Morishita , Joji Tani, Takako Nomura, Teppei Sakamoto, Koji Fujita, Shima Mimura, Tomoko Tadokoro, Kyoko Oura, Mai Nakahara, Kei Takuma, Akihiro Deguchi, Takashi Himoto, Tsutomu MASAKI
- Organizer
  APASL STC 2019 TOKYO
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08984
[Presentation] miR-762はDAA治療経過中のゲノタイプ1型HCV排除に際して血清中に増加する2018
- Author(s)
  米山弘人、森下朝洋、藤田浩二、野村貴子、坂本鉄平、田所智子、大浦杏子、谷　丈二、出口章広、樋本尚志、三村志麻、正木　勉
- Organizer
  第22回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-16K09361
[Presentation] C型肝炎起因性肝細胞癌におけるバイオマーカーとしての血清miR-125a-5pの有用性2018
- Author(s)
  大浦杏子、田所智子、藤田浩二、三村志麻、坂本鉄平、野村貴子、森下朝洋、米山弘人、正木　勉
- Organizer
  第22回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-16K09361
[Presentation] Serum Concentration of Galectin-9 Correlates to Liver Fibrosis.2017
- Author(s)
  Fujita K, Morishita A, Yoneyama H, Niki T, Nishimoto N, Himoto T, Masaki T.
- Organizer
  APASL STC 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09361
[Presentation] 胆管細胞癌におけるガレクチン-9 による増殖抑制効果の検討2015
- Author(s)
  小林聖幸、藤田浩二、大倉亮一、山下拓磨、西岡智子、谷　丈二、三好久昭、坂本鉄平、藤森崇行、加藤清仁、鎌田英紀、森下朝洋、米山弘人、正木　勉
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  熊本市
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25460998
[Presentation] 劇症肝炎におけるガレクチン-9の有効性について2015
- Author(s)
  田所智子、森下朝洋、米山弘人、三好久昭、谷　丈二、野村貴子、坂本鉄平、藤田浩二、三村志麻、明石瑛美子、大浦杏子、正木　勉
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  熊本市
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-25460998

1. MASAKI Tsutomu (30335848)

# of Collaborated Projects: 8 results

# of Collaborated Products: 23 results
2. IWAMA Hisakazu (20398035)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
3. Morishita Asahiro (60423430)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
4. Nomura Takako (70645415)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
5. 藤田浩二 (50749421)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
6. TANI Joji (00596075)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
7. HIMOTO Takashi (20325343)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
8. KOSAKA Hiroaki (60158897)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 小原英幹 (10612476)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
10. 坂本鉄平 (30769328)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. DEGUCHI Akihiro (30380174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SUZUKI Yasuyuki (40304092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MIYOSHI Hisaaki (40592316)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
14. HIRASHIMA Mitsuomi (70109700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
15. SEIYAMA Akitoshi (70206605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. FUJII Shigemoto (00325333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. YAMAMOTO Akira (70314911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 森宏仁 (20568844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
19. 仁木敏朗 (40558508)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
20. 田所智子 (50813177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 大浦杏子 (80834639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. MASAKI Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 脇田隆字

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 北中明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 服部俊夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YONEYAMA Hirohito 米山 弘人

Research Projects

Research Products

Co-Researchers

Development of a method to predict the severity of nonalcoholic fatty liver disease by measuring body composition and microRNAPrincipal Investigator

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Development of a method to predict the severity of nonalcoholic fatty liver disease by exosomal microRNAPrincipal Investigator

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[Journal Article] Identification of microRNA associated with the elimination of hepatitis C virus genotype 1b by direct-acting antiviral therapies2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association between microRNA?527 and glypican?3 in hepatocellular carcinoma2021

Author(s)

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DOI

Data Source

[Journal Article] Comprehensive analysis of circulating microRNAs as predictive biomarkers for sorafenib therapy outcome in hepatocellular carcinoma2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fibrosis Staging Using Direct Serum Biomarkers is Influenced by Hepatitis Activity Grading in Hepatitis C Virus Infection.2018

Author(s)

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Data Source

[Journal Article] Serum miRNAs Predicting Sustained HBs Antigen Reduction 48 Weeks after Pegylated Interferon Therapy in HBe Antigen-Negative Patients.2018

Author(s)

Journal Title

Data Source

[Journal Article] Galectin-9 ameliorates fulminant liver injury.2017

YONEYAMA Hirohito 米山弘人