SHIRAISHI ISAO 白石公

… Alternative Names

SHIRAISHI Isao 白石公

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Researcher Number	80295659
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Affiliation (Current)	2023: 国立研究開発法人国立循環器病研究センター, 病院, 客員研究員
Affiliation (based on the past Project Information) *help	2022 – 2023: 国立研究開発法人国立循環器病研究センター, 病院, 客員研究員 2019 – 2021: 国立研究開発法人国立循環器病研究センター, オープンイノベーションセンター, 部長 2020: 国立研究開発法人国立循環器病研究センター, オープンイノベーションセンター・教育推進部, 部長 2015 – 2017: 国立研究開発法人国立循環器病研究センター, 病院, 部長 2015: 国立循環器病研究センター, 病院, 部長 … More 2012 – 2014: 独立行政法人国立循環器病研究センター, 病院, 部長 2010 – 2011: 独立行政法人国立循環器病研究センター, 小児循環器部, 部長 2009: National Cardiovascular Center Research Institute, 小児循環器診療部, 部長 2008: 京都府立医科大学, 医学部附属病院, 講師 2008: National Cardiovascular Center Research Institute, 小児循環器診療部, 部長 2008: National Cardiovascular Center Research Institute, 小児循環器診療部, 部長 2003 – 2007: Kyoto Prefectural University of medicine, Graduate School of Medical Science, Assistant Professor, 医学研究科, 講師 2000 – 2002: 京都府立医科大学, 医学部, 講師 1997 – 1999: Kyoto Prefectural University of Medicine Accistant, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Pediatrics / Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics / Pediatrics / Basic Section 55030:Cardiovascular surgery-related / Medical systems / Biomedical engineering/Biomaterial science and engineering
Keywords	Principal Investigator Akt / 川崎病 / 抗SSA抗体 / 僧帽弁閉鎖不全 / 急性心不全 / 先天性心疾患 / PKB / 核移行 / アポトーシス / 遺伝子治療 … More / 心不全 / FAK / Rho / 心内膜炎 / 遺伝子異常 / 催奇形 / レチノイン酸 / 心臓形態形成 / 網羅的解析 / トランスクリプトーム / メタゲノム / 腱索断裂 / SSA抗体 / 乳児 / トランスクリプトーム解析 / DNA網羅的解析 / 僧帽弁腱索 / 僧帽弁検索断裂 / RNAトランスクリプトーム解析 / メタゲノム解析 / 僧帽弁腱索断裂 / cardiac hypertrophy / transgenic mouse / nuclear translocation / apoptosis / heart failure / 遺伝子導入 / 心筋細胞 / 生存シグナル / 心肥大 / トランスジェニックマウス / Nuclear Localization signal / Apoptosis / Gene Therapy / Heart Failure / 細胞内シグナル伝達 / 核移行シグナル / cardiac morphogenesis / small G protein / 筋原線維 / 低分子G蛋白質 / 心ループ / 先天性心奇形 / 心形態形成 / 低分子G蛋白 / extracellular matrix / knockout mouse / collagen III / gene targetting / collagen type III / ノックアウトマウス / 細胞外基質 / コラーゲンIII型 / mitral choral rupture / 循環器 / 小児科 / 臨床医学 / 心臟形態形成 / 遺伝子 / ファロー四徴症 / ファロー四徴 / 大血管転位 / 二次心臓領域 / 転写因子 / 催奇形性 / 心臓発生 … More Except Principal Investigator 先天性心疾患 / Flt-1 / VEGF / Flk-1 / 血管内皮細胞 / 肺上皮細胞 / Kawasaki disease / 動脈硬化 / 川崎病 / クロストーク / 肺血管形成 / 急性心不全 / 腱索断裂 / 乳児特発性僧帽弁腱索断裂 / TGF-β / SMAD4 / endoglin / SMAD / BMPシグナル / 遺伝性出血性末梢血管拡張症 / ACVRL1 / 成人先天性心臓外科 / 血流解析 / 成人先天性心疾患 / シグナル伝達 / 血管病 / 心血管発生 / embryo / mouse / lung / vasculogenesis / angiogenesis / 共焦点レーザー走査顕微鏡 / Angiogenesis / pulmonary vasculature / congenital heart disease / 間葉細胞 / 共焦点レーザー顕微鏡 / 肺 / 胎仔肺 / 血管新生 / 肺循環 / チアノーゼ性心疾患 / screening / athersclerosis / endothelial function / NO関連因子 / スクリーニング / 血管内皮機能 / Macrophage / Smooth muscle cell / High Cholesterol diet / Healed angitis / Animal model / Atherogenesis / 血管内膜肥厚 / 高脂血症 / 血管炎 / 高コレステロール血症 / 早発粥状硬化 / 冠動脈炎 / マクロファージ / 平滑筋細胞 / 高コレステロール食 / 治癒冠動脈炎 / 動物モデル / 異種情報の連携 / ベクトルシェーマ / 医療情報システム / コンピュータグラフィックス / 生体シミュレーション / 心不全 / 幹細胞 / 心筋細胞 / casase9 / caspase9 / FasL / 圧負荷 / 容量負荷 / アポトーシス / Flkk-1 Less

Investigation of virus RNA analysis using FFPE specimens to clarify the pathogenesis of acute rupture of chodae tendineae of the mitral valve in infants
- Principal Investigator
  
  黒嵜健一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  National Cardiovascular Center Research Institute
Downstream genes of signaling pathways implicated in human cardiovascular diseases: in vivo significance and regulatory mechanisms
- Principal Investigator
  
  中川修
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  National Cardiovascular Center Research Institute
Development of Surgical Strategy in Adult Congenital Heart Disease based on Blood Flow Imaging
- Principal Investigator
  
  板谷慶一
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Nagoya City University
  Osaka Metropolitan University
  Osaka City University
Integrated analysis of pathgenesis of hereditary hemorrhagic telangiectasia
- Principal Investigator
  
  岩朝徹
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  National Cardiovascular Center Research Institute
Transcroiptome and Metagenome Analysis of Patients with Acute Rupture of Chordae Tendeneae of the Mitral Valve in InfantsPrincipal Investigator
- Principal Investigator
  
  白石公
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  National Cardiovascular Center Research Institute
Research on Pathogenesis of Acute Rupture of Chordae Tendinae of the Mitral Valve in Infants: Possible involvement of maternally derived anti-SSA antibodyPrincipal Investigator
- Principal Investigator
  
  Shiraishi Isao
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  National Cardiovascular Center Research Institute
Technological development of heart simulators to perform heart beats in real time and multi-touch deformation available for medical care of congenital heart diseases
- Principal Investigator
  
  Nakazawa Kazuo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  National Cardiovascular Center Research Institute
Technology development of the patient information database for the congenital heart disease for combining the different kind of information
- Principal Investigator
  
  IWATA Michiaki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical systems
- Research Institution
  National Cardiovascular Center Research Institute
Acute Rupture of Chordae Tendineae of the Mitral Valve in Infants -A Nationwide Survey in Japan Exploring a New SyndromePrincipal Investigator
- Principal Investigator
  
  SHIRAISHI Isao
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  National Cardiovascular Center Research Institute
Gene expression of the secondary heart field cells of mouse model of congenital heart disease induced by maternal administration of retinoic acidPrincipal Investigator
- Principal Investigator
  
  SHIRAISHI Isao
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  National Cardiovascular Center Research Institute
Analysis of apoptosis signal and stem cells in congenital heart disease model rats.
- Principal Investigator
  
  TOIYAMA Kentaro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
Gene analysis of mouse models of visceral heterotaxy syndrome and transposition of the great arteries induced by maternal administration of retinoic acidsPrincipal Investigator
- Principal Investigator
  
  SHIRAISHI Isao
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  National Cardiovascular Center Research Institute
  Kyoto Prefectural University of Medicine
肺毛細血管新生における血管内皮細胞と肺胞上皮細胞との情報伝達の解析
- Principal Investigator
  
  山元康敏
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
Cardioprotection with nuclear-targeted Akt/PKBPrincipal Investigator
- Principal Investigator
  
  SHIRAISHI Isao
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
Basic Research of Pulmonary Angiogenesis fir the Patients with Complicated Cyanotic Congenital Heart Diseases.
- Principal Investigator
  
  HAMAOKA Kenji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
Embryonic pulmonary vascular development during murine lung morphogenesis
- Principal Investigator
  
  HAMAOKA Kenji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of medicine
Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytesPrincipal Investigator
- Principal Investigator
  
  SHIRAISHI Isao
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
The screaning of endothelial function of young adult patients with Kawasaki disease history
- Principal Investigator
  
  SAKATA Koichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
Functional Analysis of small G protein during cardiac early morphogenesisPrincipal Investigator
- Principal Investigator
  
  SHIRAISHI Isao
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine
Investigation of collagen type III knockout mousePrincipal Investigator
- Principal Investigator
  
  SHIRAISHI Isao
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  School of Medicine, Kyoto Prefectural University of Medicine
Histlogical study about accerelation of atherogenesis in healed coronary angitis
- Principal Investigator
  
  ONOUCHI Zenshiro
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto Prefectural University of Medicine

[Book] 「循環器病学-基礎と臨床-」第9章2:「先天性心疾患における発生異常、病態生理、診断および治療」2010
- Author(s)
  白石公
- Total Pages
  43
- Publisher
  西村書店(分担執筆)
- Data Source
  KAKENHI-PROJECT-21591406
[Book] 先天性心疾患を理解するための臨床心臓発生学2007
- Author(s)
  編集執筆:山岸敬幸、白石公
- Total Pages
  227
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-19591215
[Book] 先天性心疾患を理解するための心臓発生学山岸敬幸 (編)2007
- Author(s)
  白石公
- Total Pages
  227
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-19591215
[Book] Annual Review 2007 循環器 I. 循環器の生物学 7. 肺血管形成の分子生物学2007
- Author(s)
  白石公, 山元康敏, 浅妻右子
- Total Pages
  9
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-18790728
[Book] 心臓血管発生研究会テキスト 7. 肺循環の発生2006
- Author(s)
  白石公, 山元康敏
- Total Pages
  6
- Publisher
  佐々木印刷有限会社
- Data Source
  KAKENHI-PROJECT-18790728
[Journal Article] 僧帽弁閉鎖不全2018
- Author(s)
  白石　公
- Journal Title
  
  小児科診療
  
  Volume: 81 Pages: 355-356
- Data Source
  KAKENHI-PROJECT-15K09705
[Journal Article] 乳児特発性僧帽弁腱索断裂2015
- Author(s)
  白石　公
- Journal Title
  
  小児内科
  
  Volume: 小児疾患診療のための病態生理1. 改訂第5版 Pages: 259-262
- Data Source
  KAKENHI-PROJECT-15K09705
[Journal Article] 気がつかないと致死的な乳児特発性僧帽弁腱索断裂2015
- Author(s)
  白石　公
- Journal Title
  
  小児内科
  
  Volume: 47 Pages: 283-285
- Data Source
  KAKENHI-PROJECT-15K09705
[Journal Article] 乳児特発性僧帽弁腱索断裂2014
- Author(s)
  白石公
- Journal Title
  
  小児疾患診療のための病態生理1. 改訂第5版, 小児内科
  
  Volume: 46 Pages: 259-262
- Data Source
  KAKENHI-PROJECT-24591594
[Journal Article] Acute rupture of chordae tendineae of the mitral valve in infants: a nationwide survey in Japan exploring a new syndrome.2014
- Author(s)
  Shiraishi I, Nishimura K, Sakaguchi H, Abe T, Kitano M, Kurosaki K, Kato H, Nakanishi T, Yamagishi H, Sagawa K, Ikeda Y, Morisaki T, Hoashi T, Kagisaki K, Ichikawa H.
- Journal Title
  
  Circulation
  
  Volume: 130 Issue: 13 Pages: 1053-1061
- DOI
  10.1161/circulationaha.114.008592
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591594, KAKENHI-PROJECT-25293238
[Journal Article] 僧帽弁閉鎖不全2014
- Author(s)
  白石公
- Journal Title
  
  小児科診療 2014年増刊号小児の治療指針
  
  Volume: 77 Pages: 353-354
- Data Source
  KAKENHI-PROJECT-24591594
[Journal Article] 三次元心臓モデルのリアルタイム形状変形を実現するマルチタッチインタラクションシステムの技術開発2014
- Author(s)
  小山裕己, 五十嵐健夫, 井尻敬, 稲田慎, 黒嵜健一, 白石公, 中沢一雄
- Journal Title
  
  医療情報学
  
  Volume: 34(5) Pages: 221-232
- NAID
  130005148399
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25282138
[Journal Article] 乳児特発性僧帽弁腱索断裂による急性心不全2013
- Author(s)
  白石公、坂口平馬、北野正尚、黒嵜健一、池田義彦、帆足孝也、鍵崎康治、市川肇
- Journal Title
  
  循環器病研究の進歩
  
  Volume: 34 Pages: 52-57
- Data Source
  KAKENHI-PROJECT-24591594
[Journal Article] 特集クローズアップ新しい子どもの病気. 循環器疾患-最近注目されるようになった疾患 > 「乳児特発性僧帽弁腱索断裂」2013
- Author(s)
  白石　公
- Journal Title
  
  「小児内科」
  
  Volume: 45
- Data Source
  KAKENHI-PROJECT-24591594
[Journal Article] ＜最近注目されるようになった病気＞乳児特発性僧帽弁腱索断裂2013
- Author(s)
  白石　公
- Journal Title
  
  小児内科
  
  Volume: 45 Pages: 1117-1121
- Data Source
  KAKENHI-PROJECT-24591594
[Journal Article] Heterotaxy Syndrome-from Molecular Mechanisms to Clinical Features and Managements2012
- Author(s)
  Shiraishi I, Morishima M, Sanbe A, Ichikawa H
- Journal Title
  
  Circulation J
  
  Volume: 76(Invited Review) Pages: 1329-1330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591406
[Journal Article] Simulative operation on congenital heart disease using rubber-like urethane stereo-lithographic biomodels based on 3D datasets of multi-slice computed tomography.2010
- Author(s)
  Shiraishi I, Yamagishi M, Hamaoka K, Fukuzawa M, Yagihara T
- Journal Title
  
  Eur J Cardiothorac Surg. 37(2)
  
  Pages: 302-306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591406
[Journal Article] Linear shadows inside coronary arterial lesions on two-dimensional echocardio-grahpy in Kawasaki disease patients.2009
- Author(s)
  Hamaoka A, Niboshi A, Shiraishi I, Itoi T, Hamaoka K., et al.
- Journal Title
  
  J Cardiol. 53(3)
  
  Pages: 349-54
- NAID
  10025183702
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591406
[Journal Article] Intrapartum fetal heart rate monitoring in cases of congenital heart disease.2009
- Author(s)
  Ueda K, Ikeda T, Shiraishi I., et al.
- Journal Title
  
  Am J Obstet Gynecol. 201(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591406
[Journal Article] 肺の発生とVEGF2009
- Author(s)
  白石公,山元康敏,高松哲郎
- Journal Title
  
  分子呼吸器病
  
  Volume: 13 Pages: 86-91
- Data Source
  KAKENHI-PROJECT-21591406
[Journal Article] A neonate with the rupture of mitral chordae tendinae associated with maternal-derived anti-SSA antibody.2009
- Author(s)
  Hamaoka A, Shiraishi I, Yamagishi M, Hamaoka K.
- Journal Title
  
  Eur J Pediatr. 168(6
  
  Pages: 741-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591406
[Journal Article] 肺の発生とVEGF2009
- Author(s)
  白石公, 山元康敏, 高松哲郎
- Journal Title
  
  分子呼吸器病 13
  
  Pages: 86-91
- Data Source
  KAKENHI-PROJECT-19591215
[Journal Article] 第3の心筋原基としての心外膜前駆細胞(epicardium-derived progenitor cell)-多様な分化能と心筋再生の可能性-2008
- Author(s)
  白石公
- Journal Title
  
  日本小児循環器学会雑誌 24
  
  Pages: 615-619
- NAID
  10024844801
- Data Source
  KAKENHI-PROJECT-19591215
[Journal Article] 第3の心筋原基としての心外膜前駆細胞-多様な分化能と心筋再生の可能性-2008
- Author(s)
  白石公
- Journal Title
  
  日本小児循環器学会雑誌 24
  
  Pages: 615-619
- Data Source
  KAKENHI-PROJECT-19591215
[Journal Article] CT/MDCTの有用性と限界へのチャレンジ2008
- Author(s)
  白石公
- Journal Title
  
  Heart View 12
  
  Pages: 1188-1199
- Data Source
  KAKENHI-PROJECT-19591215
[Journal Article] 第3の心筋原基としての心外膜前駆細胞-多様な分化能と心筋再生の可能性-2008
- Author(s)
  白石公
- Journal Title
  
  日本小児循環器学会雑誌
  
  Volume: 24 Pages: 615-619
- Data Source
  KAKENHI-PROJECT-21591406
[Journal Article] 肺の発生とVEGF2008
- Author(s)
  白石公, 山元康敏, 高松哲郎
- Journal Title
  
  分子呼吸器病 13
  
  Pages: 86-91
- Data Source
  KAKENHI-PROJECT-19591215
[Journal Article] Detection of TUNEL-positive cardiomyocytes and c-kit-positive progenitor cells in children with congenital heart disease.2007
- Author(s)
  Sato H, Shiraishi I, Takamatsu T, Hamaoka K.
- Journal Title
  
  J Mol Cell Cardiol. 43
  
  Pages: 254-261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591215
[Journal Article] Duplication of the entire 22.9 Mb human chromosome 21 syntenic region on mouse chromosome 16 causes cardiovascular and gastrointestinal abnormalities.2007
- Author(s)
  Li Z, Yu T, Morishima M, Pao A, Laduca J, Conroy J, Nowak N, Matsui S, Shiraishi I, Yu YE.
- Journal Title
  
  Hum Mol Genet. 16(11)
  
  Pages: 1359-61
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] Regulation of embryonic lung vascular development by vascular endothelial growth factor receptors, Flk-1 and Flt-1.2007
- Author(s)
  Yamamoto Y, Shiraishi I, Dai P, Hamaoka K, Takamatsu T.
- Journal Title
  
  Anatomical Record 290
  
  Pages: 958-973
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591215
[Journal Article] 肺血管形成における分子生物学2007
- Author(s)
  白石公, 山元康敏, 浅妻右子
- Journal Title
  
  Annual Review 2007 2007(1)
  
  Pages: 37-47
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] Nuclear targeting of Akt antagonizes aspects of cardiomyocyte hypertrophy.2007
- Author(s)
  Tsujita Y, Muraski J, Shiraishi I, Kato T, Kajstura J, Anversa P, Sussman MA
- Journal Title
  
  Proc Nat1 Acad Sci U S A. 103・32
  
  Pages: 11946-11951
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] Duplication of the entire 22.9 Mb human chromosome 21 syntenic region on mouse chromosome 16 causes cardiovascular and gastrointestinal abnormalities.2007
- Author(s)
  Li Z, Yu T, Morishima M, Pao A, Laduca J, Conroy J, Nowak N, Matsui S, Shiraishi I, Yu YE
- Journal Title
  
  Hum Mol Genet. 16・11
  
  Pages: 1359-1366
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] Duplication of the entire 22.9 Mb human chromosome 21 syntenic region on mouse chromosome 16 causes cardiovascular and gastrointestinal abnorm alities.2007
- Author(s)
  Li Z, Yu T, Morishima M, Pao A, La Duca J, Conroy J, Nowak N, Matsui S, Shiraishi I, Yu E.
- Journal Title
  
  Hum Mol Genet. 16
  
  Pages: 1359-1366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591215
[Journal Article] レチノイン酸投与Right Isomerismモデルマウスでは異常肺胞-毛細血管形成を呈する2007
- Author(s)
  山元康敏, 白石公, 高松哲郎, 浜岡建城
- Journal Title
  
  日本小児科学会雑誌 111巻2号
- Data Source
  KAKENHI-PROJECT-18790728
[Journal Article] A case in a child of giant left-atrial myxoma associated with recurrent high fever and myxoma cells expressing interleukin-6.2006
- Author(s)
  Shiraishi I, Yamagishi M, Tanaka T, Hamaoka K, et al.
- Journal Title
  
  Eur J Pediatr. 165(5)
  
  Pages: 346-347
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] A case in a child of giant left-atrial myxoma associated with recurrent high fever and myxoma cells expressing interleukin-6.2006
- Author(s)
  Shiraishi I, Yamagishi M, Kato R, Okumura Y, Sato H, Tanaka T, Hamaoka K.
- Journal Title
  
  Eur J Pediatr. 165(5)
  
  Pages: 346-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] Nuclear targeting of Akt antagonizes aspects of cardiomyocyte hypertrophy.2006
- Author(s)
  Tsujita Y, Muraski J, Shiraishi I, Kato T, Kajstura J, Anversa P, Sussman MA.
- Journal Title
  
  Proc Natl Acad Sci U S A. 103(32)
  
  Pages: 11946-51
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] Teratogenic effects of bis-diamine on the developing cardiac conduction system.2006
- Author(s)
  Kise K, Nakagawa M, Okamoto N, Hanato T, Watanabe N, Nishijima S, Fujino H, Takeuchi Y, Shiraishi I
- Journal Title
  
  Birth Defects Res A Clin Mol Teratol. 73(8)
  
  Pages: 547-554
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] Stereolithographic biomodeling of congenital heart disease by multislice computed tomography imaging.2006
- Author(s)
  Shiraishi I, Kajiyama Y, Yamagishi M, Hamaoka K
- Journal Title
  
  Circulation 113・17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] Maternal Administration of Retinoic Acid Induced Abnormal Arrangement of Alveolar-Capillary Interface Associated with Complicated Heart Anomalies in Mouse Embryo2006
- Author(s)
  Yamamoto Y., Shiraishi I., Hamaoka K.
- Journal Title
  
  Ciculation Journal 70
  
  Pages: 474-474
- Data Source
  KAKENHI-PROJECT-18790728
[Journal Article] Stereolithgraphic biomodeling of congenital heart disease by using volumetric data obtained from multi-slice CT2006
- Author(s)
  Shiraishi I, Kajiyama Y, Yamagishi Hamaoka K
- Journal Title
  
  Circulation. 113(5)(in press)
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] Nuclear targeting of Akt antagonizes aspects of cardiomyocyte hypertrophy.2006
- Author(s)
  Tsujita Y, Muraski-J, Shiraishi I, Kato T, Kajstura J, Anversa P, Sussman MA.
- Journal Title
  
  Proc Natl Acad Sci U S A. 103(32)
  
  Pages: 11946-11951
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] レチノイン酸投与Right Isomerismモデルマウスでは異常肺胞-毛細血管形成を呈する2006
- Author(s)
  山元康敏, 白石公, 高松哲郎, 浜岡建城
- Journal Title
  
  日本小児循環器学会雑誌 22巻3号
  
  Pages: 303-303
- Data Source
  KAKENHI-PROJECT-18790728
[Journal Article] Maternal Administration of Retinoic Acid Induced Abnormal Arrangement of Alveolar-Capillary Interface Associated with Complicated Heart Anomalies in Mouse Embryo2006
- Author(s)
  Yamamoto Y., Shiraishi I., Takamatsu T., Hamaoka K.
- Journal Title
  
  Proceeding in The 12th WEINSTEIN Cardiovascular Development Conference
  
  Pages: 107-107
- Data Source
  KAKENHI-PROJECT-18790728
[Journal Article] A case in a child of giant left-atrial myxoma associated with recurrent high fever and myxoma cells expressing interleukin-6.2006
- Author(s)
  Shiraishi I, Yamagishi M, Kato R, Okumura Y, Sato H, Tanaka T, Hamaoka K
- Journal Title
  
  Eur J Pediatr. 165・5
  
  Pages: 346-347
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] Maternal Administration of Retinoic Acid Induced Abnormal Arrangement of Alveolar-Capillary Interface Associated with Complicated Heart Anomalies in Mouse Embryo2006
- Author(s)
  Yamamoto Y., Shiraishi I., Takamatsu T., Hamaoka K.
- Journal Title
  
  Proceeding in The 10th Molecular Cardiovascular Conference
  
  Pages: 180-180
- Data Source
  KAKENHI-PROJECT-18790728
[Journal Article] Images in cardiovascular medicine. Stereolithographic biomodeling of congenital heart disease by multislice computed tomography imaging.2006
- Author(s)
  Shiraishi I, Kajiyama Y, Yamagishi M, Hamaoka K.
- Journal Title
  
  Circulation. 113(17)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] マウス胎仔の肺毛細血管形成過程におけるVEGF-VEGFRシグナルの関与.2005
- Author(s)
  山元泰敏, 白石公, 高松哲郎, 浜岡建城
- Journal Title
  
  日本小児循環器学会雑誌 21
  
  Pages: 333-333
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591047
[Journal Article] Teratogenic effects of bis-diamine on the developing cardiac conduction system.2005
- Author(s)
  Kise K, Nakagawa M, Okamoto N, Hanato T, Watanabe N, Nishijima S, Fujino H, Takeuchi Y, Shiraishi I.
- Journal Title
  
  Birth Defects Res A Clin Mol Teratol. 73(8)
  
  Pages: 547-54
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] A child case of acute right coronary obstruction due to catheter-induced coronary dissection : successful reperfusion without stenting.2005
- Author(s)
  Shiraishi I, Sawada T, Sato H, Hayano T, Tamiya H, Hamaoka K.
- Journal Title
  
  Pediatr Cardiol. 26(4)
  
  Pages: 473-476
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] Long-term changes in coronary artery aneurysms in patients with Kawasaki disease : comparison of therapeutic regimens.2005
- Author(s)
  Onouchi Z, Hamaoka K, Sakata K, Ozawa S, Shiraishi I, Itoii T, Kiyosawa N.
- Journal Title
  
  Circ J. 69(3)
  
  Pages: 265-72
- NAID
  110002696086
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] Long-term changes in coronary artery aneurysms in patients with Kawasaki disease : comparison of therapeutic regimens.2005
- Author(s)
  Onouchi Z, Hamaoka K, Sakata K, Ozawa S, Shiraishi I, Itoi T, Kiyosawa N
- Journal Title
  
  Circ J. 69(3)
  
  Pages: 265-272
- NAID
  110002696086
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] Successful dilatation of left pulmonary artery stenosis by stent implantation through a modified Blalock-Taussig shunt in an infant with pulmonary atresia and ventricular septal defect.2005
- Author(s)
  Tanaka T, Kawakita A, Shiraishi I, Yamagishi M, Itoi T, Hamaoka K.
- Journal Title
  
  Pediatr Cardiol. 26(5)
  
  Pages: 731-733
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] Teratogenic effects of bis-diamine on the developing cardiac conduction system.2005
- Author(s)
  Kise K, Nakagawa M, Fujino H, Takeuchi Y, Shiraishi I, et al.
- Journal Title
  
  Birth Defects Res A Clin Mol Teratol. 73(8)
  
  Pages: 547-554
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] Severe heart failure due to subacute effusive-constrictive pericarditis in a child.2005
- Author(s)
  Suita C, Shiraishi I, Tanaka T, Shuntoh K, Yamagishi M, Hamaoka K.
- Journal Title
  
  Pediatr Cardiol. 26(1)
  
  Pages: 101-103
- Data Source
  KAKENHI-PROJECT-17591106
[Journal Article] マワス胎仔の肺毛細血管形成週程におけるVEGF-VEGFRシグナルの関与.2005
- Author(s)
  山元康敏, 白石公, 高松哲郎, 浜岡建城
- Journal Title
  
  日本小児循環器学会雑誌 21
  
  Pages: 333-333
- Data Source
  KAKENHI-PROJECT-16591047
[Journal Article] A child case of acute right coronary obstruction due to catheter-induced coronary dissection : successful reperfusion without stenting.2004
- Author(s)
  Shiraishi, I., Hamaoka, K., et al.
- Journal Title
  
  Pediatr.Cardiol. 5
  
  Pages: 781-787
- Data Source
  KAKENHI-PROJECT-16591047
[Presentation] 過去のFFPE切片からを用いたRNAトランスクリプトーム解析および高感度in situ hybridization法による乳児特発性僧帽弁腱索断裂の病態および病原微生物の検討2021
- Author(s)
  白井学、白石公
- Organizer
  第57回日本小児循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08290
[Presentation] 乳児特発性僧帽弁腱索断裂の臨床的特徴2018
- Author(s)
  白石　公
- Organizer
  第24回日本SIDS・乳幼児突然死予防学会学術集会　特別講演
- Invited
- Data Source
  KAKENHI-PROJECT-15K09705
[Presentation] 血行動態表示付き先天性心疾患のシェーマ作成支援Webアプリケーションの開発2016
- Author(s)
  毛受久実，田中実里，上田雄太，大星直樹，稲田慎，中沢一雄，黒嵜健一，白石公
- Organizer
  電子情報通信学会関西支部学生会　第21回学生研究発表講演会
- Place of Presentation
  兵庫県立大学姫路工学キャンパス（兵庫県・姫路市）
- Year and Date
  2016-03-01
- Data Source
  KAKENHI-PROJECT-25282138
[Presentation] EDUCATION / SIMULATION AND TECHNOLOGY / INNOVATIONS AND ADMINISTRATION2016
- Author(s)
  K. Kurosaki, I. Shiraishi , M. Iwata , R. Haraguchi , K. Nakazawa
- Organizer
  the 8th World Congress on Pediatric Intensive and Critical Care
- Place of Presentation
  Toronto, Canada
- Year and Date
  2016-06-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25282138
[Presentation] 先天性心疾患を対象としたシェーマ作成支援Webアプリケーション -ユーザインタフェースに関する考察-2015
- Author(s)
  高平愛斗，岩田倫明，黒嵜健一，白石公，中沢一雄，大星直樹
- Organizer
  情報処理学会グループウェアとネットワークサービス研究会
- Place of Presentation
  東京
- Year and Date
  2015-03-12
- Data Source
  KAKENHI-PROJECT-25750193
[Presentation] 先天性心疾患に伴う大血管構築異常の形態シミュレーション：心エコー画像を用いた3次元コンピューターグラフィックスの作成2015
- Author(s)
  黒嵜健一,原口亮,岩田倫明,中沢一雄,神崎歩,白石公
- Organizer
  第51回日本小児循環器学会総会・学術集会
- Place of Presentation
  ホテル日航大阪（東京都・港区）
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-25282138
[Presentation] 先天性心疾患の心臓レプリカの機能を補完しコンシューマレベルのコンピュータで実用可能なマルチタッチブラウザ2015
- Author(s)
  中沢一雄，小山裕己，中島一崇，井尻敬，稲田慎，黒嵜健一，白石公，五十嵐健夫
- Organizer
  第63回日本心臓病学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2015-09-18
- Invited
- Data Source
  KAKENHI-PROJECT-25282138
[Presentation] 先天性心疾患心臓の形状抽出と心臓レプリカを想定したマルチタッチブラウザ開発2015
- Author(s)
  中沢一雄，井尻敬，小山裕己，中島一崇，五十嵐健夫，稲田慎，原口亮，奈良崎大士，岩田倫明，芦原貴司，神崎歩，黒嵜健一，坂口平馬，市川肇，白石公
- Organizer
  第51回日本小児循環器学会総会・学術集会
- Place of Presentation
  ホテル日航大阪（東京都・港区）
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-25282138
[Presentation] 三次元モデルを用いた先天性心疾患における心臓内血流の可視化2015
- Author(s)
  田中実里，毛受久実，上田雄太，井尻敬，稲田慎，黒嵜健一，白石公，中沢一雄，大星直樹
- Organizer
  第35回医療情報学連合大会（第16回医療情報学会学術大会）
- Place of Presentation
  沖縄コンベンションセンター（沖縄県・宜野湾市）
- Year and Date
  2015-11-01
- Data Source
  KAKENHI-PROJECT-25282138
[Presentation] A New Application of Automatic Illustration System for Better Understanding of Complex Congenital Heart Diseases2014
- Author(s)
  Kenichi Kurosaki, Heima Sakaguchi, Michiaki Iwata, Ryo Haraguchi, Kazuo Nakazawa, Isao Shiraishi
- Organizer
  The 78th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-25282138
[Presentation] 遠隔医療における多職種コミュニケーションツールとしての新しいシェーマシステムの試み2014
- Author(s)
  黒嵜健一，坂口平馬，岩田倫明，原口亮，中沢一雄，吉松淳，白石公
- Organizer
  第50回日本小児循環器学会総会・学術集会
- Place of Presentation
  岡山
- Year and Date
  2014-07-03
- Data Source
  KAKENHI-PROJECT-25750193
[Presentation] Technological Development of Heart Simulators for Various Computer Platforms in the Medical and Health-care Fields2014
- Author(s)
  Kazuo Nakazawa, Shin Inada, Ryo Haraguchi, Takashi Ashihara, Isao Shiraishi, Ken-ichi Kurosaki, Suzu Kanzaki, Takeo Igarashi, Takashi Ijiri, Yuki Koyama, Takanori Ikeda
- Organizer
  The 78th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-25282138
[Presentation] 先天性心疾患を対象とした異種情報を統合可能とするベクトルシェーマシステムの開発2014
- Author(s)
  岩田倫明，原口亮，黒嵜健一，稲田慎，白石公，桑田成規，中沢一雄
- Organizer
  電子情報通信学会 MEとバイオサイバネティクス研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25282138
[Presentation] 先天性心疾患を対象としたシェーマ作成支援Webアプリケーションの開発2014
- Author(s)
  高平愛斗，岩田倫明，黒嵜健一，白石公，中沢一雄，大星直樹
- Organizer
  第34回医療情報学連合大会
- Place of Presentation
  千葉
- Year and Date
  2014-11-07
- Data Source
  KAKENHI-PROJECT-25750193
[Presentation] 異種情報を結合可能とするベクトルシェーマシステムの導入及び評価2014
- Author(s)
  岩田倫明，黒嵜健一，白石公，桑田成規，中沢一雄
- Organizer
  第34回医療情報学連合大会
- Place of Presentation
  千葉
- Year and Date
  2014-11-07
- Data Source
  KAKENHI-PROJECT-25750193
[Presentation] 先天性心疾患を対象としたベクトルシェーマシステムの病院情報システムへの導入2013
- Author(s)
  岩田倫明，原口亮，谷昇子，黒嵜健一，稲田慎，白石公，桑田成規，中沢一雄
- Organizer
  第33回医療情報学連合大会（第14回日本医療情報学会学術大会）
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25282138
[Presentation] タブレットＰＣによるマルチタッチインタラクションを活用した先天性心疾患のための診療支援システム2013
- Author(s)
  中沢一雄，小山裕己，五十嵐健夫，井尻敬，稲田慎，谷昇子，岩田倫明，奈良﨑大士，原口亮，桑田成規，神崎歩，黒嵜健一，白石公
- Organizer
  第33回医療情報学連合大会（第14回日本医療情報学会学術大会）
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25282138
[Presentation] Histopathological Features of Massive Mitral Regurgitation due to Rupture of Chordae Tendineae in Infants: Nationwide Survey in Japan2013
- Author(s)
  Shiraishi I
- Organizer
  第77回日本循環器学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24591594
[Presentation] 乳児特発性僧帽弁腱策断裂の腱索病理組織所見の検討-全国調査の結果から2013
- Author(s)
  白石公
- Organizer
  第49回日本小児循環器学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591594
[Presentation] Maternal Administration of Retinoic Acid Induces Wide Variety of Complicated Congenital Heart Disease in Mice Embryos2010
- Author(s)
  白石公
- Organizer
  第74回日本循環器学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2010-03-07
- Data Source
  KAKENHI-PROJECT-21591406
[Presentation] Current Topics of Cardiac Embryology for Congenital Heart Disease2009
- Author(s)
  Shiraishi I
- Organizer
  第5回China-Korea-Japan Pediatric Heart Forum
- Place of Presentation
  Beijing
- Data Source
  KAKENHI-PROJECT-21591406
[Presentation] Current topics on cardiac embryology for congenital heart disease2009
- Author(s)
  Shiraishi I
- Organizer
  The 5^<th> China-Korea-Japan Pediatric Heart Forum
- Place of Presentation
  Beijing
- Data Source
  KAKENHI-PROJECT-21591406
[Presentation] DiGeorge syndrome-like outflow tract phenotype induced by maternal administration with retinoic acid and its gene profiles2008
- Author(s)
  Shiraishi I, Moroshima M Sanbe A, Hamaoka K.
- Organizer
  Weinstein Cardiovascular Development Conference 2009
- Place of Presentation
  Houston, Texas, USA
- Data Source
  KAKENHI-PROJECT-19591215
[Presentation] DiGeorge Syndrome-Like Outflow Tract Phenotype Induced by Maternal Administration with Retinoic Acid2007
- Author(s)
  Shiraishi I, Moroshima M, Sanbe A, Hamaoka K
- Organizer
  Weinstein Cardiovascular Development Conference
- Place of Presentation
  Indianapolis
- Data Source
  KAKENHI-PROJECT-19591215
[Presentation]2007
- Author(s)
  Shiraishi I, Morishima M, Sanbe A, Hamaoka K.
- Organizer
  Weinstein Cardiovascular Development Conference
- Place of Presentation
  Indianapolis, USA
- Data Source
  KAKENHI-PROJECT-19591215
[Presentation] 先天性心疾患を対象とした異種情報を結合可能とするベクトルシェーマシステムの開発
- Author(s)
  岩田倫明，原口亮，黒嵜健一，白石公，桑田成規，中沢一雄
- Organizer
  電子情報通信学会 MEとバイオサイバネティクス研究会
- Place of Presentation
  玉川大学
- Data Source
  KAKENHI-PROJECT-25750193
[Presentation] 手で触れることのできるシミュレーターの開発：複雑先天性心疾患の３次元診断, 外科手術シミュレーション, 医学教育の向上をめざした精密心臓レプリカとその応用
- Author(s)
  白石公
- Organizer
  第50回日本小児循環器学会総会・学術集会
- Place of Presentation
  岡山コンベンションセンター（岡山市北区）
- Year and Date
  2014-07-03 – 2014-07-05
- Data Source
  KAKENHI-PROJECT-25282138
[Presentation] 先天性心疾患を対象としたベクトルシェーマシステムの病院情報システムへの導入
- Author(s)
  岩田　倫明，原口　亮，谷　昇子，黒嵜　健一，稲田　慎，白石　公，桑田　成規，中沢　一雄
- Organizer
  第33回医療情報学連合大会
- Place of Presentation
  神戸ファションマート
- Data Source
  KAKENHI-PROJECT-25750193
[Presentation] Clinical and Histopathologic Features of Acute Rupture of Mitral Chordae Tendinae in Infants
- Author(s)
  Shiraishi, I.
- Organizer
  European Society of `cardiology 2013
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-24591594

1. HAMAOKA Kenji (60189602)

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2. KUROSAKI Kenichi (40561460)

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3. SHIRAI Manabu (70294121)

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5. Nakazawa Kazuo (50198058)

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6. IWATA Michiaki (30631296)

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28. TAKAMATSU Tetsuro (40154900)

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47. 石川泰輔 (60708692)

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SHIRAISHI ISAO 白石 公

SHIRAISHI Isao 白石 公

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Transcroiptome and Metagenome Analysis of Patients with Acute Rupture of Chordae Tendeneae of the Mitral Valve in InfantsPrincipal Investigator

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Research on Pathogenesis of Acute Rupture of Chordae Tendinae of the Mitral Valve in Infants: Possible involvement of maternally derived anti-SSA antibodyPrincipal Investigator

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Acute Rupture of Chordae Tendineae of the Mitral Valve in Infants -A Nationwide Survey in Japan Exploring a New SyndromePrincipal Investigator

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Gene expression of the secondary heart field cells of mouse model of congenital heart disease induced by maternal administration of retinoic acidPrincipal Investigator

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Gene analysis of mouse models of visceral heterotaxy syndrome and transposition of the great arteries induced by maternal administration of retinoic acidsPrincipal Investigator

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Cardioprotection with nuclear-targeted Akt/PKBPrincipal Investigator

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SHIRAISHI ISAO 白石公

SHIRAISHI Isao 白石公

[Book] 先天性心疾患を理解するための心臓発生学山岸敬幸 (編)2007