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MIZUNO Hideaki  水野 秀昭

ORCIDConnect your ORCID iD *help
… Alternative Names

水野 英昭  ミズノ ヒデアキ

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Researcher Number 80301779
Affiliation (based on the past Project Information) *help 2009: 細胞機能探索技術開発チーム, 専門職研究員
2005 – 2009: 独立行政法人理化学研究所, 細胞機能探索技術開発チーム, 専門職研究員
2003: 独立行政法人理化学研究所, 細胞機能探索技術開発チーム, 専門職研究員
2000 – 2002: Lab for Cell Function Dynamics, Laboratory Staff Scientist, The Institute of Physical and Chemical Research, RIKEN, 細胞機能探索技術開発チーム, 研究員
2000: 理化学研究所, 細胞機能端探索技術開発チーム, 研究員
Review Section/Research Field
Except Principal Investigator
Biological Sciences / Living organism molecular science / Biophysics
Keywords
Except Principal Investigator
RFP / pericam / GFP / 蛍光タンパク質 / circularly-permuted GFP / バイオイメージング / カルモデュリン / Ca^<2+>センサー / cameleon / Bioimaging … More / Fluorescent Protein / in vitro mutagenesis / random mutagenesis / calmodulin / Ca^<2+> indicator / 蛍光偏光度測定 / プレートイメージアナライザー / レーザー走査顕微鏡 / カルシウムイメージング / 試験管内進化 / ランダム変異導入 / 神経前駆細胞 / 蛍光イメージング / 膜電位 / レシオイメージング / 細胞周期 / 蛍光蛋白質 / Red Fluorescent Protein / Green Fluorescent Protein / 蛍光エネルギー移動 / 1分子イメージング / エバネセント / 2光子励起 / サファイア / FRET / 落射蛍光顕微鏡 / イメージング / カルシウム / YFP / Kaede / photoconversion / 層流 / チロシンリン酸化 / EGF / 発色団 / プロテインキナーゼC / グリア細胞 / インテグリン / シナプス形成 / ヒユサンゴ / Digital Micromirror Device Less
  • Research Projects

    (4 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (10 People)
  •  Photomodulatable fluorescent proteins

    • Principal Investigator
      ATSUSHI Miywaki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      The Institute of Physical and Chemical Research
  •  New approaches for imaging and controlling the molecules of life.

    • Principal Investigator
      MIYAWAKI Atsushi
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  cameleon1分子イメージングによる局所的カルシウム動態の解析

    • Principal Investigator
      MIYAWAKI Atsushi
    • Project Period (FY)
      1999 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Imaging of Synamics of Cellular Functions using GFP-based probes

    • Principal Investigator
      MIYAWAKI Atsushi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Biophysics
    • Research Institution
      The Institute of Physical and Chemical Research, RIKEN

All 2009 2008 2007 2006 2005

All Journal Article Presentation Book Patent

  • [Book] Adv. Biochem. Eng. Biotechnol.(Engineering fluorescent proteins., 95)2005

    • Author(s)
      Miyawaki A, Nagai T, Mizuno H.
    • Data Source
      KAKENHI-PROJECT-17017039
  • [Journal Article] The E1 mechanism in photo-induced β-elimination reactions for green-to red conversion of fluorescent proteins2009

    • Author(s)
      Tsutsui H, Shimizu H, Mizuno H, Nukina N, Furuta T, Miyawaki A.
    • Journal Title

      Chemistry & Biology 16

      Pages: 1140-1147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017039
  • [Journal Article] The E1 mechanism in photo-induced β-elimination reactions for green-to red conversion of fluorescent proteins.2009

    • Author(s)
      Tsutsui H, Shimizu H, Mizuno H, Nukina N, Furuta T, Miyawaki A.
    • Journal Title

      Chemistry & Biology 16

      Pages: 1140-1147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017039
  • [Journal Article] Light-dependent regulation of structural flexibility in a photochromic fluorescent protein,2008

    • Author(s)
      Mizuno H., et. al.
    • Journal Title

      Proc Natl Acad Sci U S A. (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18310150
  • [Journal Article] Two-photon dual-color imaging using fluorescent proteins.2008

    • Author(s)
      Kawano H, Kogure T, Abe Y, Mizuno H, Miyawaki A.
    • Journal Title

      Nat Methods. 5(5)

      Pages: 373-374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017039
  • [Journal Article] Light-dependent regulation of structural flexibility in a photochromic fluorescent protein.2008

    • Author(s)
      Mizuno H., et. al.
    • Journal Title

      Proc Natl Acad Sci U S A. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18310150
  • [Journal Article] Light-dependent regulation of structural flexibility in a photochromic fluorescent protein2008

    • Author(s)
      Mizuno H, Kumar Mal T, Walchli M, Kikuchi A, Fukano T, Ando R, Jeyakanthan J, Taka J, Shiro Y, Ikura M, Miyawaki A.
    • Journal Title

      Proc. Natl. Acad. Sci. USA. 105

      Pages: 9927-9932

    • Data Source
      KAKENHI-PROJECT-17017039
  • [Journal Article] Highlighted generation of fluorescence signals using simultaneous two-color irradiation on Dronpa mutants2007

    • Author(s)
      Ando R, Flors C, Mizuno H, Hofkens J, Miyawaki A
    • Journal Title

      Biophysical J. 92

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017039
  • [Journal Article] Concatenation of Cyan and Yellow Fluorescent Proteins for Efficient Resonance Energy Transfer.2006

    • Author(s)
      Shimozono S; Hosoi H; Mizuno H; Fukano T; Tahara T; Miyawaki A.
    • Journal Title

      Biochemistry 45

      Pages: 6267-6271

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017039
  • [Journal Article] Reversible single-molecule photoswitching in the GFP-like fluorescent protein Dronpa.2005

    • Author(s)
      Habuchi S, Ando R, Dedecker P, Verheijen W, Mizuno H, Miyawaki A, Hofkens J.
    • Journal Title

      Proc.Natl.Acad.Sci.USA. 102巻

      Pages: 9551-9516

    • Data Source
      KAKENHI-PROJECT-17017039
  • [Journal Article] Engineering fluorescent proteins.2005

    • Author(s)
      Miyawaki A, Nagai T, Mizuno H.
    • Journal Title

      Adv.Biochem.Eng.Biotechnol. 95巻

      Pages: 1-15

    • Data Source
      KAKENHI-PROJECT-17017039
  • [Patent] 蛍光蛋白質2005

    • Inventor(s)
      宮脇敦史、安藤亮子、水野秀昭
    • Industrial Property Rights Holder
      理化学研究所
    • Filing Date
      2005-05-20
    • Data Source
      KAKENHI-PROJECT-17017039
  • [Presentation] New fluorescent probes and new perspectives in bioscience2008

    • Author(s)
      Miyawaki A., Sakaue-Sawano A., Ando R., Mizuno H., Kogure T., Kurokawa H., Sugiyama M., Sugimura K.
    • Organizer
      Focus on Microscopy 2008
    • Year and Date
      2008-04-14
    • Data Source
      KAKENHI-PROJECT-17017039
  • 1.  MIYAWAKI Atsushi (80251445)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 10 results
  • 2.  TSUTSUI Hidekazu (30392038)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 3.  HAMA Hiroshi (30261796)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  NAGAI Takeharu (20311350)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  FUKANO Takashi (80373364)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 6.  SHIMOZONO Satoshi (40391982)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  MIYAUCHI Takayuki (00392142)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  河野 弘幸 (10332256)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  IBATA Keiji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  VETRIVEL Lakshmanan
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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