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OKADA TAROU  岡田 太郎

… Alternative Names

岡田 太郎  オカダ タロウ

OKADA Tarou  岡田 太郎

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Researcher Number 80304088
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-5183-9402
Affiliation (Current) 2025: 神戸大学, 医学研究科, 准教授
Affiliation (based on the past Project Information) *help 2022 – 2023: 神戸大学, 医学研究科, 准教授
2016 – 2020: 神戸大学, 医学研究科, 准教授
2014 – 2015: 神戸大学, 大学院医学研究科, 准教授
2012 – 2015: 神戸大学, 医学(系)研究科(研究院), 准教授
2011 – 2012: 神戸大学, 大学院・医学研究科, 准教授 … More
2008 – 2011: 神戸大学, 医学研究科, 准教授
2008: 神戸大学, 大学院・医学研究科, 准教授
2007: Kobe University, Graduate School of Medicine, Associate Professor
2006: 神戸大学, 医学系研究科, 助教授
2005: 神戸大学, 大学院医学系研究科, 助教授
2002 – 2004: 神戸大学, 大学院・医学系研究科, 講師
2001: 神戸大学, 大学院・医学系研究科, 助手
1998 – 2000: 神戸大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Biological pharmacy / Basic Section 44010:Cell biology-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / General medical chemistry / Functional biochemistry
Except Principal Investigator
Respiratory organ internal medicine / General medical chemistry / Pathological medical chemistry / Biological Sciences / Basic Section 49010:Pathological biochemistry-related … More / Medium-sized Section 48:Biomedical structure and function and related fields / Pathological medical chemistry / General medical chemistry / Functional biochemistry Less
Keywords
Principal Investigator
スフィンゴ脂質 / パーキンソン病 / スフィンゴシン1リン酸 / スフィンゴシン1-リン酸 / スフィンゴシンキナーゼ / S1P / S1P受容体 / α-シヌクレイン / エクソソーム / スフィンゴシン1-リン酸 … More / シグナル伝達 / Gqタンパク質 / シヌクレイノパチー / 神経変性疾患 / カテプシンD / 逆行性輸送 / リソソーム / αシヌクレイン / パルミトイル化 / スフィンゴシン1-リン酸受容体 / ガングリオシド / スフィンゴシン1リン酸受容体 / 神経伝達物質放出 / スフィンゴシン1リン酸 … More
Except Principal Investigator
スフィンゴシンキナーゼ / スフィンゴシン1リン酸 / 細胞内情報伝達 / S1P / エキソソーム / S1P受容体 / スフィンゴシン・キナーゼ / コリン燐脂質 / ADP-リボシル化因子 / G_<M2>アクチベーター / ホスホリパーゼD / パーキンソン病 / 気管支喘息 / 神経伝達物質 / グルタミン酸 / 海馬 / エンドソーム / マクロピノサイトーシス / ホスホイノシタイド / レビー小体 / αシヌクレイン / スフィンゴシン1燐酸 / 後期エンドソーム / LBPA / リゾビスフォスファチジン酸 / スフィンゴシン1リン酸 / bronchial asthma / lung fibroblast / sphingosine kinase / sphingosine 1-phosphate / 急性喘息モデル / 線維芽細胞 / ADP-ribosvlation factor / G-protein / G_<M2> activator / Phospholipase D / Signal transduction / 癌微細環境 / Met / 治療 / 気道リモデリング / 気道炎症 / 国際情報交換 / マウス / 卵白アルブミン / 樹状細胞 / IL-33 / IL-25 / TSLP / JTE013 / 喘息 / スフィンゴシン1リン酸受容体 / スフィンゴシン1燐酸(SIP) / GABA / 分子病態学 / goblet cells / IL-13 / ERK / mucin / Shingosine kinase / SlP受容体 / Sphingosine kinase / 粘液産生 / スフィンゴシン / 苔状線維 / 自発放出 / 核移行シグナル / 核排出シグナル / 生理活性 / 生体分子 / 脂質 / 酵素 / シグナル伝達 / イノシトール燐脂質 / スフィンゴシン1燐酸 / スフィンゴ脂質 / 小胞輸送 / 酵母ツーハイブリッド法 / PXドメイン / RPK118 / 初期エンドソーム / ADP―リボシル化因子 / ホスファチジルイノシトール4,5二リン酸 / ホスファチジルコリン / プロテイン・キナーゼC / ADPリボシル化因子 Less
  • Research Projects

    (20 results)
  • Research Products

    (64 results)
  • Co-Researchers

    (12 People)
  •  シヌクレイノパチーにおける細胞外αシヌクレインによる新規病変伝播機構の解明Principal Investigator

    • Principal Investigator
      岡田 太郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      Kobe University
  •  Involvement of S1P receptor signaling and exosome release on Parkinson's diseasePrincipal Investigator

    • Principal Investigator
      Okada Taro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Kobe University
  •  Analysis on pathogenesis of Parkinson's disease through S1P signaling

    • Principal Investigator
      Nakamura Shun-ichi
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      Kobe University
  •  Analysis of molecular mechanism underlying S1P signal-mediated exosome release

    • Principal Investigator
      Nakamura Shun-ichi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Kobe University
  •  Inhibition of S1P receptor signal transduction by extracellular alpha-synucleinPrincipal Investigator

    • Principal Investigator
      OKADA TARO
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kobe University
  •  Studies on the coupling mechanism between lysobisphosphatidic acid (LBPA) and S1P signaling

    • Principal Investigator
      Nakamura Shun-ichi
    • Project Period (FY)
      2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      Kobe University
  •  Regulation of cancer malignancy through the cargo sorting into exosomes

    • Principal Investigator
      NAKAMURA Shun-ichi
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kobe University
  •  S1P receptors on neuronal cells as a target of medicine for epilepsyPrincipal Investigator

    • Principal Investigator
      OKADA Taro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kobe University
  •  Role of sphingolipids in the respiratory immune system

    • Principal Investigator
      NISHIMURA Yoshihiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Kobe University
  •  Mechanism underlying the regulation of brain function through sphingosine kinase/S1P signaling

    • Principal Investigator
      NAKAMURA Shunichi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Kobe University
  •  The role of sphingosine kinases on the formation of neural network in dentate granule cells of hippocampusPrincipal Investigator

    • Principal Investigator
      OKADA Taro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Kobe University
  •  The control of airway mucus secretion via sphingosine signals

    • Principal Investigator
      NISHIMURA Yoshihiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Kobe University
  •  スフィンゴ脂質による神経伝達物質放出機構の解析

    • Principal Investigator
      中村 俊一
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  Studies on the mechanism of nucleo/cytoplasmic shuttling of sphingosine kinase

    • Principal Investigator
      NAKAMURA Shunichi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kobe University
  •  Research of sphingosine kinase modification in acute lung injury

    • Principal Investigator
      NISHIMURA Yoshihiro
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Kobe University
  •  スフィンゴシン1リン酸に結合する核内受容体の同定Principal Investigator

    • Principal Investigator
      岡田 太郎
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      Kobe University
  •  エンドソーム形成の分子メカニズムの解析

    • Principal Investigator
      中村 俊一
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      Kobe University
  •  低分子G蛋白質ARF依存性ホスホリパーゼDの活性化機構の解析

    • Principal Investigator
      NAKAMURA Shunichi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (B)
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  Studies on the mechanism of activation of phospholipase D

    • Principal Investigator
      NAKAMURA Shun-ichi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kobe University
  •  G_<M2>アクチベーターによるホスホリパーゼDの活性化機構に関する研究

    • Principal Investigator
      中村 俊一
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional biochemistry
    • Research Institution
      Kobe University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2005 Other

All Journal Article Presentation Book

  • [Book] 細胞工学2015

    • Author(s)
      梶本武利、岡田太郎、中村俊一
    • Total Pages
      5
    • Publisher
      秀潤社
    • Data Source
      KAKENHI-PROJECT-24590112
  • [Book] 細胞内外で機能するスフィンゴシン1リン酸(S1P)の役割2012

    • Author(s)
      岡田太郎、中村俊一
    • Publisher
      生化学
    • Data Source
      KAKENHI-PROJECT-21590309
  • [Journal Article] Extracellular <scp>α‐synuclein</scp> impairs sphingosine 1‐phosphate receptor type 3 (<scp>S1PR3</scp>)‐regulated lysosomal delivery of cathepsin D in <scp>HeLa</scp> cells2024

    • Author(s)
      Nishida Susumu、Matovelo Shubi Ambwene、Kajimoto Taketoshi、Nakamura Shun‐ichi、Okada Taro
    • Journal Title

      Genes to Cells

      Volume: 29 Issue: 3 Pages: 207-216

    • DOI

      10.1111/gtc.13093

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06206, KAKENHI-PROJECT-23K06360, KAKENHI-PROJECT-20K07289
  • [Journal Article] Identification of novel OCRL isoforms associated with phenotypic differences between Dent disease-2 and Lowe syndrome2021

    • Author(s)
      Sakakibara Nana、Ijuin Takeshi、Horinouchi Tomoko
    • Journal Title

      Nephrology Dialysis Transplantation

      Volume: 37 Issue: 2 Pages: 262-270

    • DOI

      10.1093/ndt/gfab274

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K15864, KAKENHI-PROJECT-22K06206
  • [Journal Article] Involvement of Receptor-Mediated S1P Signaling in EGF-Induced Macropinocytosis in COS7 Cells2020

    • Author(s)
      Shubi Ambwene Matovelo, Lifang Zhang, Nesma Nabil Ibrahim Mohamed, Taketoshi Kajimoto, Takeshi Ijuin, Taro Okada, Shun-Ichi Nakamura
    • Journal Title

      Kobe J Med Sci

      Volume: 66

    • NAID

      120006975791

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06657
  • [Journal Article] Involvement of receptor-mediated S1P signaling in EGF-induced macropinocytosis in COS7 cells2020

    • Author(s)
      Matovelo Shubi Ambwene, Zhang Lifang, Mohamed Nesma Nabil Ibrahim, Kajimoto Taketoshi, Ijuin Takeshi, Okada Taro, Nakamura Shun-ichi
    • Journal Title

      Kobe J Med Sci.

      Volume: 66

    • NAID

      120006975791

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02623
  • [Journal Article] Activation of atypical protein kinase C by sphingosine 1-phosphate revealed by an aPKC-specific activity reporter2019

    • Author(s)
      Kajimoto Taketoshi、Caliman Alisha D.、Tobias Irene S.、Okada Taro、Pilo Caila A.、Van An-Angela N.、Andrew McCammon J.、Nakamura Shun-ichi、Newton Alexandra C.
    • Journal Title

      Science Signaling

      Volume: 12 Issue: 562

    • DOI

      10.1126/scisignal.aat6662

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08594, KAKENHI-PROJECT-15KK0307, KAKENHI-PROJECT-18K06657, KAKENHI-PROJECT-18H02623, KAKENHI-PROJECT-18K19430
  • [Journal Article] Extracellular α-synuclein drives sphingosine 1-phosphate receptor subtype 1 out of lipid rafts, leading to impaired inhibitory G protein signaling.2018

    • Author(s)
      Badawy SMM, Okada T, Kajimoto T, Hirase M, Matovelo SA, Nakamura S, Yoshida D, Ijuin T, Nakamura SI.
    • Journal Title

      Journal of Biological Chemistry

      Volume: in press Issue: 21 Pages: 8208-8216

    • DOI

      10.1074/jbc.ra118.001986

    • NAID

      120006554634

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08585, KAKENHI-PROJECT-15K07930, KAKENHI-PROJECT-17K08594, KAKENHI-PROJECT-18K06657, KAKENHI-PROJECT-18K19430, KAKENHI-PROJECT-18H02623
  • [Journal Article] Involvement of Gβγ subunits of Gi protein coupled with S1P receptor on multivesicular endosomes in F-actin formation and cargo sorting into exosomes2018

    • Author(s)
      Kajimoto, T., Mohamed, N.N.I., Badawy, S.M.M., Matovelo, S.A., Hirase, M., Nakamura, S., Yoshida, D., Okada, T., Ijuin, T., Nakamura, S.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 293 Issue: 1 Pages: 245-253

    • DOI

      10.1074/jbc.m117.808733

    • NAID

      120006554633

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08594, KAKENHI-PROJECT-15K07930
  • [Journal Article] Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells2018

    • Author(s)
      Mohamed Nesma Nabil Ibrahim, Okada Taro, Kajimoto Taketoshi, Nakamura Shun-ichi
    • Journal Title

      Kobe J Med Sci.

      Volume: 25;63(4)

    • NAID

      120006471054

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02623
  • [Journal Article] DHHC5-mediated palmitoylation of S1P receptor subtype 1 determines G-protein coupling2017

    • Author(s)
      Badawy SMM, Okada T, Kajimoto T, Ijuin T, Nakamura SI.
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 16552-16552

    • DOI

      10.1038/s41598-017-16457-4

    • NAID

      120006380402

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08585, KAKENHI-PROJECT-17K08594, KAKENHI-PROJECT-15K07930
  • [Journal Article] Extracellular α-synuclein induces sphingosine 1-phosphate receptor subtype 1 uncoupled from inhibitory G-protein leaving β-arrestin signal intact.2017

    • Author(s)
      Zhang L, Okada T, Badawy SM, Hirai C, Kajimoto T, Nakamura SI.
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 44248-44248

    • DOI

      10.1038/srep44248

    • NAID

      120006380401

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460341, KAKENHI-PROJECT-15K07930
  • [Journal Article] Impairment of PDGF-induced chemotaxis by extracellular α-synuclein through selective inhibition of Rac1 activation2016

    • Author(s)
      Okada, T., Hirai, C., Badawy, S., Zhang, L., Kajimoto, T., Nakamura, SI.
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 37810-37810

    • DOI

      10.1038/srep37810

    • NAID

      120005898707

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460341, KAKENHI-PROJECT-15K07930
  • [Journal Article] High expression of Mcl-1L via the MEK-ERK-phospho-STAT3 (Ser727) pathway protects melanocytes and melanoma from UVB-induced apoptosis.2016

    • Author(s)
      Fukumoto-T, Iwasaki-T, Okada-T, Hashimoto-T, Moon-Y, Sakaguchi-M, Fukami-Y, Nishigori-C, Oka-M.
    • Journal Title

      Genes Cells.

      Volume: 21 Issue: 2 Pages: 185-199

    • DOI

      10.1111/gtc.12330

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07930, KAKENHI-PROJECT-15K19689, KAKENHI-PROJECT-26461692
  • [Journal Article] エキソソームの形成機構2015

    • Author(s)
      梶本武利、岡田太郎、中村俊一
    • Journal Title

      細胞工学

      Volume: 34 Pages: 168-173

    • Data Source
      KAKENHI-PROJECT-15K15066
  • [Journal Article] エキソソームの形成機構2015

    • Author(s)
      梶本武利、岡田太郎、中村俊一
    • Journal Title

      細胞工学

      Volume: 34 Pages: 168-173

    • Data Source
      KAKENHI-PROJECT-26670158
  • [Journal Article] Sphingosine kinases modulate the secretion of amyloid β precursor protein from SH-SY5Y neuroblastoma cells: the role of α-synuclein2014

    • Author(s)
      Jesko, H., Okada, T., Strosznajder, R. P., & Nakamura, S.
    • Journal Title

      Folia Neuropathol.

      Volume: 52 Pages: 70-78

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670158
  • [Journal Article] Sphingosine kinases modulate the secretion of amyloid β precursor protein from SH-SY5Y neuroblastoma cells: the role of α-synuclein.2014

    • Author(s)
      Jesko H, Okada T, Strosznajder RP, Nakamura S.
    • Journal Title

      Folia Neuropathol

      Volume: 52 Pages: 70-78

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24590112
  • [Journal Article] Ongoing activation of sphingosine 1-phosphate receptors mediates maturation of exosomal multivesicular endosomes.2013

    • Author(s)
      Taketoshi Kajimoto, Taro Okada, Satoshi Miya, Lifang Zhang, Shun-ichi Nakamura
    • Journal Title

      Nature Communications

      Volume: 4:2712 Issue: 1 Pages: 1-13

    • DOI

      10.1038/ncomms3712

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790293, KAKENHI-PROJECT-24590112
  • [Journal Article] 細胞内外で機能するスフィンゴシン1リン酸(S1P)の役割2012

    • Author(s)
      岡田太郎、中村俊一
    • Journal Title

      生化学

      Volume: 84 Pages: 92-101

    • NAID

      10030346307

    • Data Source
      KAKENHI-PROJECT-22390053
  • [Journal Article] Regulation of synaptic strength by sphingosine 1-phosphate in the hippocampus2010

    • Author(s)
      Kanno T, Nishizaki T, Proia RL, Kajimoto T, Jahangeer S, Okada T, Nakamura S
    • Journal Title

      Neuroscience

      Volume: 29 Pages: 973-80

    • Data Source
      KAKENHI-PROJECT-21590309
  • [Journal Article] Sphingosine kinase 1 regulates mucin production via ERK phosphorylation2010

    • Author(s)
      Kono Y, Nishiuma T, Okada T, Kobayashi K, Funada Y, Kotani Y, Jahangeer S, Nakamura S, Nishimura Y
    • Journal Title

      Pulm Pharmacol Ther

      Volume: 23(1) Pages: 36-42

    • NAID

      120003290046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590965
  • [Journal Article] Sphingosine kinase 1 regulates mucin production via ERK phosphorylation2010

    • Author(s)
      Kono Y, Nishiuma T, Okada T, Kobayashi K, Funada Y, Kotani Y, Jahangeer S, Nakamura S, Nishimura Y
    • Journal Title

      Pulm Pharmacol Ther

      Volume: 23 Pages: 36-42

    • NAID

      120003290046

    • Data Source
      KAKENHI-PROJECT-21590309
  • [Journal Article] Regulation of synaptic strength by sphingosine 1-phosphate in the hippocampus.2010

    • Author(s)
      Kanno, T., Nishizaki, T., Proia, R. L., Kajimoto, T., Jahangeer, S., Okada, T., & Nakamura, S.
    • Journal Title

      Neurosci

      Volume: 171 Pages: 973-980

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390053
  • [Journal Article] Sphingosine kinase 1 regulates mucin production via ERK phosphorylation2010

    • Author(s)
      Kono, Y., Nishiuma, T., Okada, T., Kobayashi, K., Funada, Y., Kotari, Y., Jahangeer, S., Nakamura S., Nishimura Y.
    • Journal Title

      Pulm.Pharmacol.Ther.

      Volume: 23 Pages: 36-42

    • NAID

      120003290046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390053
  • [Journal Article] Regulation of synaptic strength by sphingosine 1-phosphate in the hippocampus2010

    • Author(s)
      Kanno, T., Nishizaki, T., Proia, L., Kajimoto, T., Jahangeer, S., Okada., T., Nakamura, S
    • Journal Title

      Neuroscience

      Volume: 171 Pages: 7-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390053
  • [Journal Article] Sphingosine kinase 1 regulates mucin production via ERK phosphorylation2010

    • Author(s)
      Kono, Y., Nishiuma, T., Okada, T., Kobayashi, K., Funada, Y., Kotani, Y., Jahangeer, S., Nakamura, S., Nishimura, Y.
    • Journal Title

      Pulm.Pharmacol.Ther. 23

      Pages: 36-42

    • NAID

      120003290046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20022026
  • [Journal Article] Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system2009

    • Author(s)
      Okada, T., Kajimoto, T., Jahangeer, S., Nakamura, S.
    • Journal Title

      Cell. Signal 21

      Pages: 7-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590309
  • [Journal Article] Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system2009

    • Author(s)
      Okada T, Kajimoto T, Jahangeer S, Nakamura S
    • Journal Title

      Cell Signal

      Volume: 21 Pages: 7-13

    • Data Source
      KAKENHI-PROJECT-21590309
  • [Journal Article] Roles of extracellular and intracellular sphingosine 1-phosphate in cell migration2009

    • Author(s)
      Yu H, Okada T, Kobayashi M, Abo-Elmatty DM, Jahangeer S, Nakamura S
    • Journal Title

      Genes Cells

      Volume: 14 Pages: 597-605

    • Data Source
      KAKENHI-PROJECT-21590309
  • [Journal Article] CtBP1/BARS is an activator of phospholipase D1 necessary for agonist-induced macropinocytosis2009

    • Author(s)
      Haga, Y., Miwa, N., Jahangeer, S., Okada, T., Nakamura, S.
    • Journal Title

      EMBO J. 28

      Pages: 1197-1207

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20022026
  • [Journal Article] Roles of extracellular and intracellular sphingosine 1-phosphate in cell migration2009

    • Author(s)
      Yu, H., Okada, T., Kobayashi, M., Abo-Elmatty, D.M., Jahangeer, S., Nakamura, S.
    • Journal Title

      Genes Cells 14

      Pages: 597-605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20022026
  • [Journal Article] Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system2009

    • Author(s)
      Okada, T., Kajimoto, T., Jahangeer, S., & Nakamura, S.
    • Journal Title

      Cell. Signal. 21

      Pages: 7-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20022026
  • [Journal Article] CtBP1/BARS is an activator of phospholipase D1 necessary for agonist-induced macropinocytosis2009

    • Author(s)
      Haga Y, Miwa N, Jahangeer S, Okada T, Nakamura S
    • Journal Title

      EMBO J

      Volume: 28 Pages: 1197-207

    • Data Source
      KAKENHI-PROJECT-21590309
  • [Journal Article] Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model2008

    • Author(s)
      Nishiuma, T, Nishimura, Y, Okada, T, Kuramoto, E, Kotani, Y, Jahangeer, S, Nakamura, S
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590848
  • [Journal Article] Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model2008

    • Author(s)
      Nishiuma, T., Nishimura, Y., Okada, T., Kuramoto, E., Kotani, Y., Jahangeer, S., & Nakamura, S.
    • Journal Title

      Am. J. Physiol. Lung Cell. Mo1. Physiol. 294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590309
  • [Journal Article] Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model2008

    • Author(s)
      Nishiuma, T., Nishimura, Y., Okada, T., Kuramoto, E., Kotani, Y., Jahangeer, S., Nakamura, S.
    • Journal Title

      Am. J. Physiol. Lung Cell. Mol. Physiol. 294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590309
  • [Journal Article] Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model.2008

    • Author(s)
      Nishiuma T, Nishimura Y, Okada T, Kuramoto E, Kotani Y, Jahangeer S, Nakamura S
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590848
  • [Journal Article] Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model2008

    • Author(s)
      Nishiuma, T., Nishimura, Y., Okada, T., Kuramoto, E., Kotani, Y., Jahan geer, S., & Nakamura, S.
    • Journal Title

      Am. J. Physiol. Lung Cell. Mol. Physiol. 294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20022026
  • [Journal Article] Involvement of sphingosine-1-phosphate in glutamate secretion in hippocampal neurons2007

    • Author(s)
      Kajimoto, T., Okada, T., Yu, F., Goparaju, S. K., Jahangeer, S., Nakamura. S.
    • Journal Title

      Mol. Cell. Biol. 27

      Pages: 3429-3440

    • NAID

      10024355377

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590309
  • [Journal Article] Involvement of sphingosine-1-phosphate in glutamate secretion in hippocampal neurons2007

    • Author(s)
      Kajimoto, T., Okada, Y., Yu, H., Goparaju, S., Jahangeer, S. & Nakamura, S.
    • Journal Title

      Mol. Cell. Biol. 27

      Pages: 3429-3440

    • NAID

      10024355377

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590309
  • [Journal Article] Sphingosine kinase 1 regulates differentiation of human and mouse lung fibroblasts mediated by TGF{beta}12007

    • Author(s)
      Kono, Y., Nishiuma, T., Nishimura, Y., Kotani, Y., Okada, T., Nakamura, S., Yokoyama M.
    • Journal Title

      Am. J. Respir. Cell. Mol. Biol. 37

      Pages: 395-404

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590309
  • [Journal Article] Requirement of phospholipase D for ilimaquinone-induced Golgi membrane fragmentation2007

    • Author(s)
      Sonoda, H., Okada, T., Jahangeer, S., and Nakamura, S.
    • Journal Title

      J. Biol. Chem. 282

      Pages: 34085-34092

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590309
  • [Journal Article] Sphingosine kinase 1 regulates differentiation of human and mouse lung fibroblasts mediated by TGF-beta12007

    • Author(s)
      Kono, Y, Nishiuma, T, Nishimura, Y, Kotani, Y, Okada, T, Nakamura, S, Yokoyama, M
    • Journal Title

      Am J Respir Cell Mol Biol 37

      Pages: 395-404

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590848
  • [Journal Article] Requirement of phospholipase D for ilimaquinone-induced Golgi membrane fragmentation2007

    • Author(s)
      Sonoda, H., Okada, T., Jahangeer, S., Nakamura, S.
    • Journal Title

      J. Biol. Chem. 282

      Pages: 34085-34092

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590309
  • [Journal Article] Sphingosine kinase 1 regulates differentiation of human and mouse lung fibroblasts mediated by TGF-beta12007

    • Author(s)
      Kono Y, Nishiuma T, Nishimura Y, Kotani Y, Okada T, Nakamura S, Yokoyama M.
    • Journal Title

      Am J Respir Cell Mol Biol 37

      Pages: 395-404

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590848
  • [Journal Article] Protein kinase D-mediated phosphorylation and nuclear export of sphingosine kinase 22007

    • Author(s)
      Ding, G., Sonoda, H., Yu, H., Kajimoto, T., Goparaju, S. K., Jahangeer, S., Okada, T., Nakamura, S.
    • Journal Title

      J. Biol. Chem. 282

      Pages: 27493-27502

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590309
  • [Journal Article] Protein kinase D-mediated phosphorylation and nuclear export of sphingosine kinase 22007

    • Author(s)
      Ding G, Sonoda H, Yu H, Kajimoto T, Goparaju SK, Jahangeer S, Okada T, Nakamura S.
    • Journal Title

      J. Biol. Chem. 282

      Pages: 27493-27502

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590309
  • [Journal Article] Involvement of N-terminal-extended form of sphingosine kinase 2 in Serum-dependent regulation of cell proliferation and apoptosis2005

    • Author(s)
      岡田 太郎
    • Journal Title

      The Journal of Biological Chemistry 280

      Pages: 36318-36325

    • Data Source
      KAKENHI-PROJECT-16770098
  • [Presentation] SphK1/S1P受容体系はエンドソームからTGNへのCI-M6PRの逆行輸送に寄与することでライソゾーム酵素Cathepsin Dの活性を制御する2023

    • Author(s)
      西田晋,中村俊一,岡田太郎
    • Organizer
      第96回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-22K06206
  • [Presentation] 細胞外α-シヌクレインによるスフィンゴシン-1-リン酸受容体の阻害とその影響2022

    • Author(s)
      岡田太郎
    • Organizer
      第15回セラミド研究会・第16回スフィンゴテラピィ研究会合同学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K06206
  • [Presentation] Regulation of multivesicular body maturation by S1P signaling2013

    • Author(s)
      Nakamura, S., Kajimoto, T., Miya, S., Zhang, L., and Okada, T.
    • Organizer
      8th Sphingo-therapy conference
    • Place of Presentation
      Yamanakaonsen-Kajikaso Royal Hotel
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590112
  • [Presentation] Sphingolipid signaling and neuronal function2011

    • Author(s)
      Nakamura, S., Fukai, E., Miya, S., Jesko, H., & Okada, T.
    • Organizer
      52nd International Conference onthe Bioscience of Lipids
    • Place of Presentation
      Warsaw, Poland
    • Year and Date
      2011-09-02
    • Data Source
      KAKENHI-PROJECT-22390053
  • [Presentation] Sphingolipid signaling and neuronal function2011

    • Author(s)
      Nakamura, S., Fukai, E., Miya, S., Jesko, H., Okada, T.
    • Organizer
      52^<nd> International Conference on the Bioscience of Lipids
    • Place of Presentation
      ワルシャワ(ポーランド)(招待講演)
    • Year and Date
      2011-08-03
    • Data Source
      KAKENHI-PROJECT-22390053
  • [Presentation] Nakamura, S., Fukai, E., Jesko, H., & Okada, T.2010

    • Author(s)
      Nakamura, S., Fukai, E., Jesko, H., & Okada, T.
    • Organizer
      第83回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-22390053
  • [Presentation] スフィンゴシン1リン酸による神経伝達物質放出の調節2009

    • Author(s)
      中村俊一、岡田太郎
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Year and Date
      2009-09-18
    • Data Source
      KAKENHI-PROJECT-20022026
  • [Presentation] Sphingosine 1-phosphate in physiology and pathology in the brain2009

    • Author(s)
      Nakamura, S. and Okada, T.
    • Organizer
      9th International Congress of the Polish Neuroscience Society in Warsow
    • Place of Presentation
      Poland
    • Data Source
      KAKENHI-PROJECT-21590309
  • [Presentation] スフィンゴシンキナーゼ2によるエキソソーム放出の調節2008

    • Author(s)
      中村俊一、岡田太郎
    • Organizer
      第3回スフィンゴテラピィ(STC)研究会
    • Place of Presentation
      大山(鳥取)
    • Year and Date
      2008-04-18
    • Data Source
      KAKENHI-PROJECT-20022026
  • [Presentation] スフィンゴシンキナーゼ2によるエキソソーム放出の調節2008

    • Author(s)
      中村俊一, 岡田太郎
    • Organizer
      第3回スフィンゴテラピイ(STC)研究会
    • Place of Presentation
      鳥取
    • Data Source
      KAKENHI-PROJECT-19590309
  • [Presentation] スフィンゴシンキナーゼ2によるエキソソーム放出の調節2008

    • Author(s)
      中村俊一, 岡田太郎
    • Organizer
      第3回スフィンゴテラピィ(STC)研究会
    • Place of Presentation
      大山(鳥取)
    • Year and Date
      2008-07-18
    • Data Source
      KAKENHI-PROJECT-19590309
  • [Presentation] Sphingosine Kinase(SPHK)1 Regulates Differentiation of Lung Fibroblasts Mediated by Transforming Growth Factor (TGF) beta12007

    • Author(s)
      Kono Y, Nishiuma T, Nishimura Y, Okada T, Kobayashi K, Funada Y, Kotani Y, Nakamura S, Yokoyama M
    • Organizer
      米国胸部疾患学会(American Thoracic Society)
    • Place of Presentation
      San Francisco, CA, USA
    • Year and Date
      2007-05-21
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590848
  • [Presentation] Effect of sphingosine kinase on IL-13 induced goblet cell metaplasia2007

    • Author(s)
      Kono, Y, Nishiuma, T, Nishimura, Y, Okada, T, Kobayashi, K, Funada, Y, Kotani, Y, Nakamura, S, Yokoyama, M
    • Organizer
      Asian Pacific Society of Respirology
    • Place of Presentation
      Gold Coast, Australia
    • Year and Date
      2007-12-04
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590848
  • [Presentation] Sphingosine Kinase(SPHK)1 Regulates Differentiation of Lung Fibroblasts Mediated by Transforming Growth Factor(TGF)betal2007

    • Author(s)
      Kono, Y, Nishiuma, T, Nishimura, Y, Okada, T, Kobayashi, K, Funada, Y, Kotani, Y, Nakamura, S, Yokoyama, M
    • Organizer
      American Thoracic Society
    • Place of Presentation
      San Francisco, CA, USA
    • Year and Date
      2007-05-21
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590848
  • [Presentation] Ongoing activation of sphingosine 1-phosphate receptors mediates maturation of exosomal multivesicular endosomes

    • Author(s)
      梶本武利、岡田太郎、宮聡志、張麗芳、中村俊一
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-26670158
  • 1.  NAKAMURA Shunichi (40155833)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 32 results
  • 2.  MIWA Noriko (50202354)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  KAJIMOTO Taketoshi (00509953)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 10 results
  • 4.  NISHIMURA Yoshihiro (20291453)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 8 results
  • 5.  JAHANGEER Saleem (80314475)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 6.  KOTANI Yoshikazu (90403287)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 7.  KOBAYASHI Kazuyuki (50403275)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 8.  NISHIUMA Teruaki (10379414)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 9.  伊集院 壮 (00361626)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 10.  FUNADA Yasuhiro (60437465)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  HIRATA Kenichi (20283880)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  榊原 菜々
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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