MATSUNAGA Toshiyuki 松永俊之

… Alternative Names

松永俊之マツナガトシユキ

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Researcher Number	80306274
Other IDs
Affiliation (Current)	2025: 岐阜薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 岐阜薬科大学, 薬学部, 教授 2008 – 2018: Gifu Pharmaceutical University, 薬学部, 准教授 2007: Gifu Pharmaceutical University, 薬学部, 講師 2003: 埼玉医大, 医学部, 助手 2002: 埼玉医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Pathological medical chemistry Except Principal Investigator Basic Section 47050:Environmental and natural pharmaceutical resources-related / Urology / Laboratory medicine
Keywords	Principal Investigator 抗がん剤耐性 / アルドケト還元酵素 / 抗がん剤耐性化 / 肺がん / プロスタグランジン代謝酵素 / 前立腺がん / 乳がん / 薬剤耐性 / 脂質代謝酵素 / 大腸がん … More / 肺癌 / 抗癌剤耐性 / シスプラチン / 過酸化脂質 / 抗癌剤 / 還元酵素 / 癌 / 酸化ストレス / 動脈硬化症 / 酸化 / リポタンパク質 / NADPH oxidase / 活性酸素 / 血管内皮細胞 / 糖化高密度リポタンパク … More Except Principal Investigator 植物性自然毒 / 抗がん剤耐性 / 難治がん / PC-3細胞 / LNCaP細胞 / エンザルタミド / ビカルタミド / フルタミド / 22Rv1細胞 / AKR1C3 / アルデヒド還元酵素 / 治療抵抗性 / 前立腺癌 / 心筋梗塞 / 高脂肪血症 / ＨＤＬ / リポたんぱく質 / 生活習慣病 / 走査プローブ顕微鏡 / 脂質代謝異常 / 動脈硬化症 / 生活習慣 / 脂質異常 / リポタンパク質 Less

A novel trial to develop adjuvant therapy for intractable cancers: utilization of phytotoxins
- Principal Investigator
  
  酒井英二
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Gifu Pharmaceutical University
プロスタグランジン代謝酵素阻害剤を主軸とした肺がん化学療法の開発Principal Investigator
- Principal Investigator
  
  松永俊之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Gifu Pharmaceutical University
Development of adjuvant for treatment of hormone-dependent cancers targeted to aldo-keto reductasesPrincipal Investigator
- Principal Investigator
  
  Matsunaga Toshiyuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Gifu Pharmaceutical University
Development of adjuvant for treatment of advanced colon cancer targeted to lipid-metabolizing enzymesPrincipal Investigator
- Principal Investigator
  
  Matsunaga Toshiyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Gifu Pharmaceutical University
Oxidative stress-related factor as a novel target for drug-resistant prostate cancer
- Principal Investigator
  
  Iguchi Kazuhiro
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Gifu Pharmaceutical University
Development of adjuvant therapy targeted to lipid-derived reactive aldehydes-metabolizing enzymesPrincipal Investigator
- Principal Investigator
  
  Matsunaga Toshiyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Gifu Pharmaceutical University
Relationship between high-density lipoprotein particles and dyslipidemia risk
- Principal Investigator
  
  TABUCHI Mari
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Rikkyo University
Elucidation of molecular mechanism for chemoresistance elicited by lipid peroxide-detoxifying enzymes.Principal Investigator
- Principal Investigator
  
  MATSUNAGA Toshiyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Gifu Pharmaceutical University
Elucidation of pathophysiological roles of oxidized high-density lipoprotein aimed at finding new diagnosis and treatment for vascular diseasesPrincipal Investigator
- Principal Investigator
  
  MATSUNAGA Toshiyuki
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Gifu Pharmaceutical University
糖化高密度リポタンパクは血管内皮細胞を動脈硬化へと導くか?Principal Investigator
- Principal Investigator
  
  松永俊之
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Saitama Medical University

[Journal Article] Availability of aldo-keto reductase 1C3 and ATP-binding cassette B1 as therapeutic targets for alleviating paclitaxel resistance in breast cancer MCF7 cells.2023
- Author(s)
  Matsunaga T, Horinouchi M, Saito H, Hisamatsu A, Iguchi K, Yoshino Y, Endo S, Ikari A.
- Journal Title
  
  J. Biochem.
  
  Volume: 173 Issue: 3 Pages: 167-175
- DOI
  10.1093/jb/mvac098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07033
[Journal Article] Development of cisplatin resistance in breast cancer MCF7 cells by up-regulating aldo-keto reductase 1C3 expression, glutathione synthesis and proteasomal proteolysis.2022
- Author(s)
  Kobayashi M, Yonezawa A, Takasawa H, Nagao Y, Iguchi K, Endo S, Ikari A, Matsunaga T.
- Journal Title
  
  J. Biochem.
  
  Volume: 171 Issue: 1 Pages: 97-108
- DOI
  10.1093/jb/mvab117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07033
[Journal Article] Significance of aldo-keto reductase 1C3 and ATP-binding cassette transporter B1 in gain of irinotecan resistance in colon cancer cells.2020
- Author(s)
  Matsunaga T, Okumura N, Saito H, Morikawa Y, Suenami K, Hisamatsu A, Endo S, Ikari A.
- Journal Title
  
  Chem Biol Interact.
  
  Volume: 332 Pages: 109295-109295
- DOI
  10.1016/j.cbi.2020.109295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07033
[Journal Article] Pathophysiological roles of autophagy and aldo-keto reductases in development of doxorubicin resistance in gastrointestinal cancer cells.2019
- Author(s)
  Matsunaga T, Kawabata S, Yanagihara Y, Kezuka C, Kato M, Morikawa Y, Endo S, Chen H, Iguchi K, Ikari A.
- Journal Title
  
  Chem. Biol. Interact.
  
  Volume: 314 Pages: 108839-108839
- DOI
  10.1016/j.cbi.2019.108839
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08278
[Journal Article] Aldo-keto reductase 1B10 promotes development of cisplatin resistance in gastrointestinal cancer cells through down-regulating peroxisome proliferator-activated receptor-γ-dependent mechanism.2016
- Author(s)
  Matsunaga T, Suzuki A, Kezuka C, Okumura N, Iguchi K, Inoue I, Soda M, Endo S, El-Kabbani O, Hara A, Ikari A.
- Journal Title
  
  Chem Biol Interact.
  
  Volume: 25 Pages: 142-153
- DOI
  10.1016/j.cbi.2016.07.008
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10601
[Journal Article] Roles of aldo-keto reductases 1B10 and 1C3 and ATP-binding cassette transporter in docetaxel tolerance.2016
- Author(s)
  Matsunaga T, Saito H, Endo S, Iguchi K, Soda M, El-Kabbani O, Hara A, Ikari A.
- Journal Title
  
  Free Radic Res.
  
  Volume: 50 Issue: 12 Pages: 1296-1308
- DOI
  10.1080/10715762.2016.1236373
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10601
[Journal Article] Up-Regulation of Carbonyl Reductase 1 Renders Development of Doxorubicin Resistance in Human Gastrointestinal Cancers2015
- Author(s)
  Matsunaga T, Kezuka C, Morikawa Y, Suzuki A, Endo S, Iguchi K, Miura T, Nishinaka T, Terada T, El-Kabbani O, Hara A, Ikari A.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 38 Issue: 9 Pages: 1309-1319
- DOI
  10.1248/bpb.b15-00176
- NAID
  130005096989
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460068
[Journal Article] Acquisition of doxorubicin resistance facilitates migrating and invasive potentials of gastric cancer MKN45 cells through up-regulating aldo-keto reductase 1B10.2015
- Author(s)
  Morikawa Y, Kezuka C, Endo S, Ikari A, Soda M, Yamamura K, Toyooka N, El-Kabbani O, Hara A, Matsunaga T
- Journal Title
  
  Chem. Biol. Interact.
  
  Volume: 230 Pages: 30-39
- DOI
  10.1016/j.cbi.2015.02.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460068
[Journal Article] Induction of aldo-keto reductases (AKR1C1 and AKR1C3) abolishes the efficacy of daunorubicin chemotherapy for leukemic U937 cells.2014
- Author(s)
  Matsunaga T, Yamaguchi A, Morikawa Y, Kezuka C, Takazawa H, Endo S, El-Kabbani O, Tajima K, Ikari A, Hara A
- Journal Title
  
  Anticancer Drugs
  
  Volume: 25 Issue: 8 Pages: 868-877
- DOI
  10.1097/cad.0000000000000112
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460068
[Journal Article] Exposure to 9,10-phenanthrenequinone accelerates malignant progression of lung cancer cells through up-regulation of aldo-keto reductase 1B10.2014
- Author(s)
  Matsunaga T, Morikawa Y, Haga M, Endo S, Soda M, Yamamura K, El-Kabbani O, Tajima K, Ikari A, Hara A
- Journal Title
  
  Toxicol. Appl. Pharmacol.
  
  Volume: 278 Issue: 2 Pages: 180-189
- DOI
  10.1016/j.taap.2014.04.024
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460068
[Journal Article] Nitric oxide confers cisplatin resistance in human lung cancer cells through upregulation of aldo-keto reductase 1B10 and proteasome.2014
- Author(s)
  Matsunaga T, Yamaji Y, Tomokuni T, Morita H, Morikawa Y, Suzuki A, Yonezawa A, Endo S, Ikari A, Iguchi K, El-Kabbani O, Tajima K, Hara A
- Journal Title
  
  Free Radic. Res.
  
  Volume: 48 Issue: 11 Pages: 1371-1385
- DOI
  10.3109/10715762.2014.957694
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460068
[Journal Article] Sphingosine kinase 1 plays a role in the upregulation of CD44 expression through extracellular signal-regulated kinase signaling in human colon cancer cells2013
- Author(s)
  Kawahara S, Otsuji Y, Nakamura M, Murakami M, Murate T, Matsunaga T, Kanoh H, Seishima M, Banno Y, Hara A
- Journal Title
  
  Anticancer Drugs
  
  Volume: 24(5) Issue: 5 Pages: 473-83
- DOI
  10.1097/cad.0b013e32835f705f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590667, KAKENHI-PROJECT-24590185, KAKENHI-PROJECT-24590663, KAKENHI-PROJECT-25460068
[Journal Article] Synthesis and structure-activity relationship of 2-phenyliminochromene derivatives as inhibitors for AKR1B102013
- Author(s)
  Satoshi Endo, Dawei HU, Miho Suyama, Toshiyuki Matsunaga, Kenji Sugimoto, Yuji Matsuya, Ossama El-Kabbani, Kazuo Kuwata, Akira Hara, Yukio Kitade, Naoki Toyooka
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 21(21) Issue: 21 Pages: 6378-6384
- DOI
  10.1016/j.bmc.2013.08.059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370068, KAKENHI-PROJECT-24570180, KAKENHI-PROJECT-24790114, KAKENHI-PROJECT-25460068
[Journal Article] Substrate Specificity and Inhibitor Sensitivity of Rabbit 20α-Hydroxysteroid Dehydrogenase2013
- Author(s)
  Endo S, Arai Y, Hara A, Kitade Y, Bunai Y, El-Kabbani O, Matsunaga T.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 36 Issue: 9 Pages: 1514-1518
- DOI
  10.1248/bpb.b13-00342
- NAID
  130003361524
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460068
[Journal Article] Modulation of activity and inhibitor sensitivity of rabbit aldose reductase-like protein (AKR1B19) by oxidized glutathione and SH-reagents2013
- Author(s)
  Satoshi Endo
- Journal Title
  
  Chemico-Biological Interactions
  
  Volume: 202 Issue: 1-3 Pages: 146-152
- DOI
  10.1016/j.cbi.2012.11.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570044, KAKENHI-PROJECT-22790074, KAKENHI-PROJECT-24790114
[Journal Article] Rabbit 3-hydroxyhexobarbital dehydrogenase is a NADPH-preferring reductase with broad substrate specificity for ketosteroids, prostaglandin D2, and other endogenous and xenobiotic carbonyl compounds2013
- Author(s)
  Satoshi Endo, Toshiyuki Matsunaga, Atsuko Matsumoto, Yuki Arai, Satoshi Ohno, Ossama El-Kabbani, Kazuo Tajima, Yukio Kitade, Yasuo Bunai, Shigeru Yamano, and Akira Hara
- Journal Title
  
  Biochem. Pharmacol.
  
  Volume: 86 Issue: 9 Pages: 1366-1375
- DOI
  10.1016/j.bcp.2013.08.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790114, KAKENHI-PROJECT-25460068
[Journal Article] Pathophysiological roles of aldo-keto reductases (AKR1C1 and AKR1C3) in development of cisplatin resistance in human colon cancers2012
- Author(s)
  Matsunaga T, Hojo A, Yamane Y, Endo S, El-Kabbani O, Hara A
- Journal Title
  
  Chem. Biol. Interact
  
  Volume: 202 Issue: 1-3 Pages: 234-242
- DOI
  10.1016/j.cbi.2012.09.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590102, KAKENHI-PROJECT-22790074
[Journal Article] Aldo-keto reductase 1B10 and its role in proliferation capacity of drug-resistant cancers2012
- Author(s)
  Matsunaga T, Wada Y, Endo S, Soda M, El-Kabbani O, Hara A
- Journal Title
  
  Front. Pharmacol
  
  Volume: 3 Pages: 5-11
- DOI
  10.3389/fphar.2012.00005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590102, KAKENHI-PROJECT-22790074
[Journal Article] Design, syn thesis and evaluation of caffeic ac id phenethyl ester-based inhibitors targeting a selectivity pocket in the active site of human aldo-keto reductase 1B102012
- Author(s)
  Midori Soda, Dawei Hu, Satoshi Endo, Mayuko Takemura, Jie Li, Ryogo Wa da, Syohei Ifuku, Hai-Tao Zhao, Oss ama El-Kabbani, Shozo Ohta, Keiko Y amamura, Naoki Toyooka, Akira Hara, and Toshiyuki Matsunaga
- Journal Title
  
  Eur. J. Med. Chem.
  
  Volume: 48 Pages: 321-329
- DOI
  10.1016/j.ejmech.2011.12.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790245, KAKENHI-PROJECT-22590102, KAKENHI-PROJECT-22790074
[Journal Article] Reduction of Cytotoxic <i>p</i>-Quinone Metabolites of <i>tert</i>-Butylhydroquinone by Human Aldo-keto Reductase (AKR) 1B102012
- Author(s)
  Matsunaga T.
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 27 Issue: 5 Pages: 553-558
- DOI
  10.2133/dmpk.DMPK-12-NT-012
- NAID
  130004463280
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790074
[Journal Article] Characterization of rabbit aldose reductase-like protein with 3b-hydroxysteroid dehydrogenase activity2012
- Author(s)
  Satoshi Endo
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 527 Issue: 1 Pages: 23-30
- DOI
  10.1016/j.abb.2012.07.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570044, KAKENHI-PROJECT-22790074
[Journal Article] Inhibition of Human Aldose Reductase-Like Protein (AKR1B10) by α- and γ-Mangostins, Major Components of Pericarps of Mangosteen2012
- Author(s)
  Soda M, Endo S
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 35 Issue: 11 Pages: 2075-2080
- DOI
  10.1248/bpb.b12-00538
- NAID
  130001872266
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590102, KAKENHI-PROJECT-22790074
[Journal Article] Structure ofthe His269Arg mutant of the rat aldose reductase-like protein AKR1B14 complexed with NADPH2012
- Author(s)
  Sundaram K、Endo S、Matsunaga T、Tanaka N、Hara A、El-Kabbani O
- Journal Title
  
  Acta.Crystallogr.Sect.F Struct.Biol.Cryst.Commun.
  
  Volume: 68巻 Issue: 4 Pages: 400-403
- DOI
  10.1107/s1744309112008810
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790074
[Journal Article] Reduction of cytotoxic p-quinone metabolites of tert-butylhydroquinone by human aldo-keto reductase (AKR) 1B102012
- Author(s)
  Matsunaga T、Endo S、Takemura M、Soda M、Yamamura K、Tajima K、Miura T、Terada T、El-Kabbani O、Hara A
- Journal Title
  
  Drug Metab. Pharmacokinet
  
  Volume: 27巻 Pages: 553-558
- NAID
  130004463280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790074
[Journal Article] Selective inhibition of human type-5 17β-hydroxysteroid dehydrogenase(AKR1C3) by bacchari n, a component of brazilian propolis2012
- Author(s)
  Satoshi Endo, Toshiyuki Matsunaga, Ayano Kanamori, Youko Otsuji, Hirok o Nagai, Krithika Sundaram, Ossama El-Kabbani, Naoki Toyooka, Shozo O hta and A kira
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 75 Issue: 4 Pages: 716-721
- DOI
  10.1021/np201002x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790245, KAKENHI-PROJECT-22590102, KAKENHI-PROJECT-22790074
[Journal Article] Method for Lipoproteins Using Bioformulated-Fiber Matrix Electrophoresis : Size of High-Density Lipoprotein Does Not Reflect Its Density Anal2011
- Author(s)
  Mari Tabuchi, Makoto Seo, Takayuki Inoue, Takeshi Ikeda, Akinori Kogure,Ikuo Inoue, Shigehiro Katayama, Toshiyuki Matsunaga, Akira Hara, and Tsugikazu Komoda
- Journal Title
  
  Chem
  
  Volume: 83 Issue: 3 Pages: 1131-1136
- DOI
  10.1021/ac102402c
- Data Source
  KAKENHI-PROJECT-23659310
[Journal Article] Roles of rat and human aldo-k eto reductases in metabolism of farne sol and geranylgeraniol2011
- Author(s)
  Satoshi Endo, Toshiyuki Matsunaga, Ch isato Ohta, Midori Soda, Ayano Kanam ori, Yukio Kitade, Satoshi Ohno, Kaz uo Tajima, Ossama El-Kabbani and Akir a Hara
- Journal Title
  
  Chem. Biol. Interact.
  
  Volume: 191 Issue: 1-3 Pages: 261-268
- DOI
  10.1016/j.cbi.2010.12.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790245, KAKENHI-PROJECT-22590102, KAKENHI-PROJECT-22790074
[Journal Article] Involvement of the aldo-keto reductase, AKR1B10, in mitomycin-c resistance through reactive oxygen speciesdependent mechanisms2011
- Author(s)
  Matsunaga T, Yamane Y
- Journal Title
  
  Anticancer Drugs
  
  Volume: 22 Issue: 5 Pages: 402-408
- DOI
  10.1097/cad.0b013e3283448df0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590102, KAKENHI-PROJECT-22790074
[Journal Article] Sele ctive Inhibition of the Tumor Marker Aldo-keto Reductase Family Member 1B1 0 by Oleanolic Acid2011
- Author(s)
  Mayuko Takemura, Satoshi Endo, Toshiy uki Matsunaga, Midori Soda, Hai-Tao Zhao, Ossama El-Kabbani, Kazuo Tajima, Munekazu Iimuma, and Akira Hara
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 74 Issue: 5 Pages: 1201-1206
- DOI
  10.1021/np200118q
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790245, KAKENHI-PROJECT-22590102, KAKENHI-PROJECT-22790074
[Journal Article] Nitric oxide mitigates apoptosis in human endothelial cells induced by 9, 10- phenanthrenequinone: Role of proteasomal function.2010
- Author(s)
  Toshiyuki Matsunaga, Marina Arakaki, Tetsuro Kamiya, Mariko Haga, Satoshi Endo, Ossama El-Kabbani, Akira Hara
- Journal Title
  
  Toxicology 268巻
  
  Pages: 191-197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790066
[Journal Article] -酸化窒素はフェナンスレンキノンによるヒト血管内皮細胞アポトーシスを減らす。-プロテアソーム機能の役割-2010
- Author(s)
  松永俊之
- Journal Title
  
  トキシコロジー 268
  
  Pages: 191-197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790066
[Presentation] ポリフェノールによる肺がんのパクリタキセル耐性抑制効果の検証2023
- Author(s)
  松村俊宏、遠藤智史、井口和弘、五十里彰、松永俊之
- Organizer
  第14回　岐阜薬科大学機能性健康食品研究講演会
- Data Source
  KAKENHI-PROJECT-23K06118
[Presentation] 消化器がん細胞の5-フルオロウラシル耐性獲得とアルドケト還元酵素の関連性2023
- Author(s)
  松村俊宏、柏木映理子、久松亜紀、井口和弘、遠藤智史、立松憲次郎、五十里彰、松永俊之
- Organizer
  第96回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K06118
[Presentation] エストロゲン存在下での乳がん細胞のシスプラチン耐性化におけるアルドケト還元酵素1C3、MAPキナーゼとAktの意義2022
- Author(s)
  長尾ゆきの、酒井優治、森川嘉文、久松亜紀、井口和弘、松永俊之
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07033
[Presentation] 17β-エストラジオール存在下における乳がん細胞のシスプラチン耐性獲得機序の解明　－アルドケト還元酵素とMAPキナーゼの意義－2021
- Author(s)
  長尾ゆきの，小林美緒，神保俊輔，井口和弘，遠藤智史，五十里彰，松永俊之
- Organizer
  第85回日本生化学会中部支部例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-20K07033
[Presentation] 乳がん細胞のタモキシフェン耐性獲得におけるアルドケト還元酵素1C3、グルタチオンとプロテアソームの意義2021
- Author(s)
  長尾ゆきの、米澤綾乃、鷹澤博明、久松亜紀、井口和弘、遠藤智史、五十里彰、松永俊之
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07033
[Presentation] アルドケト還元酵素とプロテアソーム阻害剤の併用による乳がん細胞のシスプラチン耐性克服効果2020
- Author(s)
  松永俊之、小林美緒、岩佐華、井口和弘、遠藤智史、五十里彰
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07033
[Presentation] 酸化ストレスに対する防御機構におけるアルドケト還元酵素1C3の意義　－グルタチオン代謝及びプロテアソーム機能との関連性－2020
- Author(s)
  小林美緒、岩佐華、長尾ゆきの、遠藤智史、五十里彰、松永俊之
- Organizer
  第84回日本生化学会中部支部例会
- Data Source
  KAKENHI-PROJECT-20K07033
[Presentation] 消化器癌細胞のドキソルビシン耐性化におけるオートファジーとアルドケト還元酵素の意義2019
- Author(s)
  松永俊之、川畑沙織、小林美緒、岩佐華、井口和弘、遠藤智史、五十里彰
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K08278
[Presentation] 乳癌細胞のシスプラチン耐性化におけるアルドケト還元酵素1C3とプロテアソームの意義2019
- Author(s)
  小林　美緒、土村　冴花、堀之内　美智、遠藤　智史、井口　和弘、五十里　彰、松永　俊之
- Organizer
  第83回日本生化学会中部支部例会
- Data Source
  KAKENHI-PROJECT-17K08278
[Presentation] 大腸がん細胞のイリノテカン耐性化におけるアルドケト還元酵素1C3とABCトランスポーターB1の意義2018
- Author(s)
  松永俊之、奥村奈央子、井口和弘、遠藤智史、五十里彰
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-15K10601
[Presentation] 大腸がん細胞のイリノテカン耐性化におけるアルドケト還元酵素1C3とABCトランスポーターB1の意義2018
- Author(s)
  松永　俊之、奥村　奈央子、井口　和弘、遠藤　智史、五十里　彰
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K08278
[Presentation] 前立腺癌の去勢抵抗性獲得における抗酸化酵素の発現変動とその意義2017
- Author(s)
  大久保沙知、井口和弘、松永俊之、加藤美咲、五十里彰
- Organizer
  第8回育薬・創薬研究センター教育フォーラム
- Place of Presentation
  岐阜薬科大学（岐阜）
- Data Source
  KAKENHI-PROJECT-15K10601
[Presentation] 乳癌細胞のパクリタキセル耐性化におけるアルドケト還元酵素1C3とABCトランスポーターB1の意義2017
- Author(s)
  堀之内　美智、松永　俊之、斎藤　晴陽、井口　和弘、遠藤　智史、五十里　彰
- Organizer
  2017年度生命科学系学会合同年次大会ConBio2017
- Data Source
  KAKENHI-PROJECT-17K08278
[Presentation] 前立腺癌細胞株における抗アンドロゲン剤の細胞増殖抑制作用への抗酸化酵素の関与2017
- Author(s)
  大久保　沙知、奥村　奈央子、山地　由紀子、堺　千紘、横山　聡、伊野　陽子、井口　和弘、五十里　彰、松永　俊之
- Organizer
  第63回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-17K08278
[Presentation] 前立腺癌細胞株における抗アンドロゲン剤の細胞増殖抑制作用への抗酸化酵素の関与2017
- Author(s)
  大久保沙知、奥村奈央子、山地由希子、堺千紘、横山聡、伊野陽子、井口和弘、五十里彰、松永俊之
- Organizer
  第63回日本薬学会東海支部大会
- Data Source
  KAKENHI-PROJECT-15K10601
[Presentation] 乳癌細胞のパクリタキセル耐性化におけるアルドケト還元酵素1C3とABCトランスポーターB1の意義2017
- Author(s)
  堀之内美智、松永俊之、斎藤晴陽、井口和弘、遠藤智史、五十里彰
- Organizer
  ConBio2017（2017年度生命科学系学会合同年次大会）
- Data Source
  KAKENHI-PROJECT-15K10601
[Presentation] ドセタキセル耐性癌細胞におけるアルドケト還元酵素とABCトランスポーターの高発現の意義2016
- Author(s)
  斎藤晴陽、松永俊之、奥村奈央子、鎌瀬今日子、井口和弘、遠藤智史、五十里彰
- Organizer
  第80回日本生化学会中部支部例会
- Place of Presentation
  三重大学（三重）
- Data Source
  KAKENHI-PROJECT-15K10601
[Presentation] 消化器癌の5-フルオロウラシル耐性化におけるアルドケト還元酵素の高発現2016
- Author(s)
  柏木映理子、松永俊之、川端沙織、井口和弘、遠藤智史、五十里彰
- Organizer
  第80回日本生化学会中部支部例会
- Place of Presentation
  三重大学（三重）
- Data Source
  KAKENHI-PROJECT-15K10601
[Presentation] 肺癌細胞のシスプラチン耐性化機序の解明　～一酸化窒素とアルドケト還元酵素の関与～.2015
- Author(s)
  山地　由希子、松永　俊之、加藤　美咲、森川　嘉文、井口　和弘、遠藤　智史、五十里　彰
- Organizer
  第61回日本薬学会東海支部大会
- Place of Presentation
  名古屋
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] 大腸癌細胞におけるマイトマイシンC代謝活性化へのアルドケト還元酵素1C3の関与2015
- Author(s)
  奥村　奈央子、松永　俊之、毛塚　ちひろ、山根　有未、遠藤　智史、五十里　彰
- Organizer
  第79回日本生化学会中部支部例会
- Place of Presentation
  松本
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] 肺癌細胞のシスプラチン耐性化機序の解明―一酸化窒素とアルドケト還元酵素の関与―2015
- Author(s)
  山地由希子、松永俊之、加藤美咲、森川嘉文、井口和弘、遠藤智史、五十里彰
- Organizer
  第61回日本薬学会東海支部大会
- Place of Presentation
  名古屋市立大学（名古屋）
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-15K10601
[Presentation] 消化器癌細胞のシスプラチン耐性化に伴うアルドケト還元酵素1B10とペルオキシソーム増殖剤応答性受容体γの発現変動2015
- Author(s)
  松永俊之、奥村奈央子、毛塚ちひろ、鈴木綾香、遠藤智史、井口和弘、五十里彰
- Organizer
  第88回日本生化学会大会　第38回日本分子生物学会年会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] 消化器癌細胞のシスプラチン耐性化に伴うアルドケト還元酵素1B10とペルオキシソーム増殖剤応答性受容体γの発現変動2015
- Author(s)
  松永俊之、奥村奈央子、毛塚ちひろ、鈴木綾香、遠藤智史、井口和弘、五十里彰
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸ポートアイランド（神戸）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K10601
[Presentation] フルタミド耐性前立腺癌細胞におけるアルドケト還元酵素の発現上昇とその意義.2015
- Author(s)
  加藤　美咲、松永　俊之、山地　由希子、井口　和弘、遠藤　智史、五十里　彰
- Organizer
  第79回日本生化学会中部支部例会
- Place of Presentation
  松本
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] 消化器癌細胞のドキソルビシン耐性獲得機序の解明　～オートファジーとアルドケト還元酵素の関与～2015
- Author(s)
  川畑　沙織、松永　俊之、柳原　裕司、森川　嘉文、毛塚　ちひろ、鈴木　綾香、柏木　映理子、遠藤　智史、五十里　彰
- Organizer
  第79回日本生化学会中部支部例会
- Place of Presentation
  松本
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] フルタミド耐性前立腺癌細胞におけるアルドケト還元酵素の発現上昇とその意義2015
- Author(s)
  加藤美咲、松永俊之、山地由希子、井口和弘、遠藤智史、五十里彰
- Organizer
  第79回日本生化学会中部支部例会
- Place of Presentation
  信州大学（松本）
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-15K10601
[Presentation] カルボニル還元酵素 CBR1 による消化器癌のドキソルビシン耐性獲得機序の解明.2014
- Author(s)
  毛塚　ちひろ、松永　俊之、鈴木　綾香、森川　嘉文、遠藤　智史、五十里　彰
- Organizer
  第78回　日本生化学会中部支部例会
- Place of Presentation
  名古屋
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] 大腸癌のドキソルビシン耐性化に伴うアルドケト還元酵素 1B10 と PPARγ の発現変動.2014
- Author(s)
  鈴木　綾香、松永　俊之、遠藤　智史、五十里　彰
- Organizer
  第78回　日本生化学会中部支部例会
- Place of Presentation
  名古屋
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] ドキソルビシン耐性化による消化器癌細胞の抗癌剤代謝・排泄能の亢進.2014
- Author(s)
  毛塚　ちひろ，松永　俊之，鈴木　綾香，鷹澤　博明，米澤　綾乃，遠藤　智史，五十里　彰
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2014
- Place of Presentation
  静岡
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] 乳癌細胞のタモキシフェン耐性化機序の解明～抗酸化能と異物代謝能の関与～.2014
- Author(s)
  米澤　綾乃、松永　俊之、鷹澤　博明、遠藤　智史、五十里　彰
- Organizer
  第78回　日本生化学会中部支部例会
- Place of Presentation
  名古屋
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] ウサギのアルドース還元酵素類似タンパクは3β-ヒドロキシステロイド脱水素酵素活性を示す2012
- Author(s)
  熊田翔、藤本愛理、遠藤智史、松永俊之、原明、田島和男、真野純一
- Organizer
  第76回日本生化学会中部支部例会
- Place of Presentation
  岡崎
- Year and Date
  2012-05-26
- Data Source
  KAKENHI-PROJECT-22790074
[Presentation] プロポリス成分baccharinによる前立腺・乳癌治療の創薬標的AKR1C3の選択的阻害2012
- Author(s)
  大辻陽子、永井寛子、金森綾野、遠藤智史、松永俊之、原明
- Organizer
  第76回日本生化学会中部支部例会
- Place of Presentation
  岡崎
- Year and Date
  2012-05-26
- Data Source
  KAKENHI-PROJECT-22790074
[Presentation] 大腸癌細胞のシスプラチン耐性獲得におけるアルドケト還元酵素の高発現の意義2012
- Author(s)
  北條杏季、松永俊之、山根有未、森田宏美、山口綾乃、遠藤智史、原明
- Organizer
  第76回日本生化学会中部支部例会
- Place of Presentation
  岡崎
- Year and Date
  2012-05-26
- Data Source
  KAKENHI-PROJECT-22790074
[Presentation] ブチルヒドロキシアニソールのキノン代謝物によるオートファジー細胞死の誘導2012
- Author(s)
  西山彩子、遠藤智史、曽田翠、竹村麻祐子、藤本愛理、松永俊之、田島和男、原明
- Organizer
  平成24年度日本薬学会東海支部例会
- Place of Presentation
  岐阜
- Year and Date
  2012-11-18
- Data Source
  KAKENHI-PROJECT-22790074
[Presentation] Pathophysiological roles of aldo-keto reductases (AKR1C1 and AKR1C3) in development of cisplatin resistance in human colon cancers2012
- Author(s)
  MatsunagaT、HojoA、YamaneY、EndoS、El-KabbaniO、HaraA
- Organizer
  16th International Symposium of Enzymology and Molecular Biology of Carbonyl Metabolism
- Place of Presentation
  ドイツ
- Data Source
  KAKENHI-PROJECT-22790074
[Presentation] Pathophysiological roles of aldo-keto reductases (AKR1C1 and AKR1C3) in development of cisplatin resistance in human colon cancers．2012
- Author(s)
  Matsunaga T.
- Organizer
  16th International Symposium of Enzymology and Molecular Biology of Carbonyl Metabolism
- Place of Presentation
  Germany
- Data Source
  KAKENHI-PROJECT-22790074
[Presentation] 肺癌細胞のシスプラチン耐性に対するアルドケト還元酵素1B10阻害剤の有用性2012
- Author(s)
  友國琢允、松永俊之、北條杏季、森川嘉文、遠藤智史、原明
- Organizer
  平成24年度日本薬学会東海支部例会
- Place of Presentation
  岐阜
- Year and Date
  2012-11-18
- Data Source
  KAKENHI-PROJECT-22790074
[Presentation] Modulation of activity and inhibitor sensitivity of rabbit aldose reductase-like protein by oxidized glutathione and SH-reagents2012
- Author(s)
  EndoS、KumadaS、FujimotoA、MatsunagaT、OhnoS、ManoJ、TajimaK、El-Ka bbaniO、HaraA
- Organizer
  16th International Symposium of Enzymology and Molecular Biology of Carbonyl Metabolism
- Place of Presentation
  ドイツ
- Data Source
  KAKENHI-PROJECT-22790074
[Presentation] 選択的AKR1B10阻害に基づく新規抗がん剤の開発研究(1)2011
- Author(s)
  胡大イ、李杰、和田亮吾、伊福翔平、曽田翠、竹村麻祐子、遠藤智史、松永俊之、原明、ZhaoHT、El-KabbaniO、豊岡尚樹
- Organizer
  平成23年度有機合成化学北陸セミナー
- Place of Presentation
  坂井
- Data Source
  KAKENHI-PROJECT-22790074
[Presentation] オキザリプラチン耐性大腸癌細胞におけるアルドケト還元酵素1B10発現と増殖能の関連性2011
- Author(s)
  和田康弘、松永俊之、飯田桂子、友國琢允、北條杏季、遠藤智史、坂野喜子、原明
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22790074
[Presentation] 大腸癌細胞のオキサリプラチン耐性におけるカルボニル還元酵素の意義2011
- Author(s)
  飯田桂子、松永俊之、和田康弘、北條杏季、遠藤智史、原明
- Organizer
  平成23年度日本薬学会東海支部例会
- Place of Presentation
  名古屋
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-22790074
[Presentation] 選択的AKR1B10阻害に基づく新規抗がん剤の開発研究(2)2011
- Author(s)
  胡大イ、李杰、松谷裕二、杉本健士、遠藤智史、松永俊之、原明、El-Kabbani O、豊岡尚樹
- Organizer
  平成23年度有機合成化学北陸セミナー
- Place of Presentation
  坂井
- Data Source
  KAKENHI-PROJECT-22790074
[Presentation] Design, synthesis and evaluation of caffeic acid phenethyl ester-based inhibitors targeting a selectivity pocket in the active site of human aldo-keto reductase (AKR) 1B102011
- Author(s)
  EndoS、MatsunagaT、SodaM、TakemuraM、HuD、LiJ、WadaR、IfukuS、ToyookaN、ZhaoHT、El-KabbaniO
- Organizer
  8th AFMC International Medicinal Chemistry Symposium
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790074
[Presentation] マイトマイシンC耐性大腸癌細胞におけるアルドケト還元酵素1B10の発現量の増加2010
- Author(s)
  山根有未、松永俊之、飯田桂子、遠藤智史、原明
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22790074
[Presentation] マイトマイシンC耐性大腸癌細胞におけるアルドケト還元酵素1B10の発現量の増加2010
- Author(s)
  山根有未、松永俊之、飯田桂子、遠藤智史、原明
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22790074
[Presentation] 動脈硬化発症機序における酸化HDLの意義の解明2008
- Author(s)
  松永俊之
- Organizer
  第54回日本薬学会東海支部総会・大会
- Place of Presentation
  名古屋市立大学薬学部
- Year and Date
  2008-07-05
- Data Source
  KAKENHI-PROJECT-19790066
[Presentation] 動脈硬化発症機序における酸化HDLの意義の解明2008
- Author(s)
  松永俊之
- Organizer
  第54回日本薬学会東海支部総会・大会
- Place of Presentation
  愛知
- Year and Date
  2008-07-05
- Data Source
  KAKENHI-PROJECT-19790066
[Presentation] 酸化高密度リポタンパクによる血管内皮細胞毒性に対する炎症性マーカーの抑制効果2008
- Author(s)
  井上由佳梨、松永俊之、新垣麻理奈、原明
- Organizer
  第81回日本生化学会大会第31回日本分子生物学会年会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19790066
[Presentation] C-reactive proteinおよびSerum amyloid Aと酸化リポタンパク質の結合2007
- Author(s)
  松永俊之、井上由佳梨、三井田孝、菰田二一、原明
- Organizer
  第53回日本薬学会東海支部総会・大会
- Place of Presentation
  愛知
- Year and Date
  2007-07-07
- Data Source
  KAKENHI-PROJECT-19790066
[Presentation] C-reactive proteinおよびSerum amyloid Aと酸化リポタンパク質の結合2007
- Author(s)
  松永俊之
- Organizer
  第53回日本薬学会東海支部総会・大会
- Place of Presentation
  名城大学薬学部
- Year and Date
  2007-07-07
- Data Source
  KAKENHI-PROJECT-19790066
[Presentation] 2-Phenyliminochromene誘導体の癌マーカーAKR1B10阻害活性に関する構造活性相関
- Author(s)
  陶山美穂、遠藤智史、松永俊之、胡大イ、杉本健士、松谷裕二、豊岡尚樹、桑田一夫、原明
- Organizer
  第41回構造活性相関シンポジウム
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] tert-ブチルヒドロキノン代謝物の細胞毒性と防御機構
- Author(s)
  遠藤　智史、陶山　美穂、西山　彩子、藤本　愛理、松永　俊之、原　明、東　華岳、田島　和男
- Organizer
  第77回日本生化学会中部支部例会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] ウサギ20α-ヒドロキシステロイド脱水素酵素 (AKR1C5) の基質特異性と阻害剤感受性
- Author(s)
  遠藤　智史、荒井　裕貴、松永　俊之、原　明、北出　幸夫
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] ドキソルビシン耐性化による胃癌細胞の転移・浸潤能の亢進
- Author(s)
  森川　嘉文、毛塚　ちひろ、下馬塲　俊、遠藤　智史、松永　俊之
- Organizer
  平成25年度日本薬学会東海支部例会
- Place of Presentation
  鈴鹿
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] ドキソルビシン代謝酵素の発現上昇による胃癌細胞の抗癌剤耐性化
- Author(s)
  毛塚　ちひろ、松永　俊之、森川　嘉文、遠藤　智史、五十里　彰、原　明
- Organizer
  日本酸化ストレス学会東海支部　第2回学術集会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] 肺癌細胞のシスプラチン耐性における一酸化窒素の意義
- Author(s)
  山地　由希子、松永　俊之、森川　嘉文、友國　琢允、加藤　美咲、遠藤　智史、五十里　彰、原　明
- Organizer
  日本酸化ストレス学会東海支部　第2回学術集会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] ダウノルビシン処理した白血病細胞におけるアルドケト還元酵素の発現上昇の意義
- Author(s)
  松永　俊之、山口　綾乃、鷹澤　博明、森川　嘉文、遠藤　智史、原　明
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] ウサギの3-hydroxyhexobarbital dehydrogenaseはketosteroids、prostaglandin D2、その他のカルボニル化合物に広い特異性を示す還元酵素である.
- Author(s)
  原　明、遠藤　智史、山野　茂、松本　淳子、荒井　裕貴、松永　俊之
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] 酸化型グルタチオン及びSH試薬によるアルドース還元酵素類似酵素(AKR1B19) の活性・阻害剤感受性の変化
- Author(s)
  藤本　愛理、遠藤　智史、熊田　翔、松永　俊之、原　明、大野　敏
- Organizer
  第77回日本生化学会中部支部例会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] ヒト大腸癌細胞のドキソルビシン抵抗性におけるアルドケト還元酵素の意義
- Author(s)
  森川　嘉文、小笠原　慎人、鈴木　綾香、遠藤　智史、松永　俊之
- Organizer
  第77回日本生化学会中部支部例会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] シスプラチン耐性前立腺癌細胞におけるアルドケト還元酵素の発現上昇とその意義
- Author(s)
  森田　宏美、森川　嘉文、米澤　綾乃、遠藤　智史、松永　俊之
- Organizer
  第77回日本生化学会中部支部例会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] 大腸癌のドキソルビシン耐性化に伴うオートファジー誘導とアルドケト還元酵素の関連性
- Author(s)
  柳原　裕司、森川　嘉文、遠藤　智史、松永　俊之
- Organizer
  第59回日本薬学会東海支部総会・大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] カルボニル還元酵素阻害活性を有するフラボノイドの構造活性相関
- Author(s)
  荒井　裕貴、遠藤　智史、宮城　菜未希、松永　俊之
- Organizer
  平成25年度日本薬学会東海支部例会
- Place of Presentation
  鈴鹿
- Data Source
  KAKENHI-PROJECT-25460068
[Presentation] アルドケト還元酵素AKR1B10高発現による消化器癌細胞のドキソルビシン感受性の低下.
- Author(s)
  松永　俊之、毛塚　ちひろ、鈴木　綾香、森川　嘉文、遠藤　智史、五十里　彰
- Organizer
  第86回　日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25460068

1. Iguchi Kazuhiro (10295545)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
2. TABUCHI Mari (60380086)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. SEO Makoto (10406473)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 酒井英二 (90235101)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ENDO Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
6. 原明

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. EL-KABBANI Ossama

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 村手隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 桑田一夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MATSUNAGA Toshiyuki 松永 俊之

松永 俊之 マツナガ トシユキ

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A novel trial to develop adjuvant therapy for intractable cancers: utilization of phytotoxins

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プロスタグランジン代謝酵素阻害剤を主軸とした肺がん化学療法の開発Principal Investigator

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Development of adjuvant for treatment of hormone-dependent cancers targeted to aldo-keto reductasesPrincipal Investigator

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Development of adjuvant for treatment of advanced colon cancer targeted to lipid-metabolizing enzymesPrincipal Investigator

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Oxidative stress-related factor as a novel target for drug-resistant prostate cancer

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Development of adjuvant therapy targeted to lipid-derived reactive aldehydes-metabolizing enzymesPrincipal Investigator

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Relationship between high-density lipoprotein particles and dyslipidemia risk

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Elucidation of molecular mechanism for chemoresistance elicited by lipid peroxide-detoxifying enzymes.Principal Investigator

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Elucidation of pathophysiological roles of oxidized high-density lipoprotein aimed at finding new diagnosis and treatment for vascular diseasesPrincipal Investigator

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糖化高密度リポタンパクは血管内皮細胞を動脈硬化へと導くか?Principal Investigator

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[Journal Article] Availability of aldo-keto reductase 1C3 and ATP-binding cassette B1 as therapeutic targets for alleviating paclitaxel resistance in breast cancer MCF7 cells.2023

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[Journal Article] Development of cisplatin resistance in breast cancer MCF7 cells by up-regulating aldo-keto reductase 1C3 expression, glutathione synthesis and proteasomal proteolysis.2022

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[Journal Article] Significance of aldo-keto reductase 1C3 and ATP-binding cassette transporter B1 in gain of irinotecan resistance in colon cancer cells.2020

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MATSUNAGA Toshiyuki 松永俊之

松永俊之マツナガトシユキ